Digital Commons Network^™

Two Men Who Invented Genetics, Michael Dietrich

Dartmouth Scholarship

A review of two books:\r\nThe Man Who Invented the Chromosome: a Life of Cyril Darlington by Oren Solomon Harman, 2004 and\r\nGeorge Beadle, and Uncommon Farmer: The Emergence of Genetics in the 20th Century, 2003 by Paul Berg and Maxine Singer.

Discovering Cell Mechanisms: The Creation Of Modern Cell Biology, Michael Dietrich

Dartmouth Scholarship

Review of Discovering Cell Mechanisms: The Creation ofModern Cell Biology. Cambridge Studies in Philosophy and Biology. By William Bechtel. Cambridge and New York: Cam-bridge University Press. xii 323 p; ill.; index. ISBN: 052181247X. 2006.

Knowing When To Draw The Line: Designing More Informative Ecological Experiments, Kathryn L. Cottingham, Jay T. Lennon, Bryan L. Brown

Dartmouth Scholarship

Linear regression and analysis of variance (ANOVA) are two of the most widely used statistical techniques in ecology. Regression quantitatively describes the relationship between a response variable and one or more continuous independent variables, while ANOVA determines whether a response variable differs among discrete values of the independent variable(s). Designing experiments with discrete factors is straightforward because ANOVA is the only option, but what is the best way to design experiments involving continuous factors? Should ecologists prefer experiments with few treatments and many replicates analyzed with ANOVA, or experiments with many treatments and few replicates per treatment analyzed with regression? …

Interleukin-17/Interleukin-17 Receptor-Mediated Signaling Is Important For Generation Of An Optimal Polymorphonuclear Response Against Toxoplasma Gondii Infection, Michelle N. Kelly, Jay K. Kolls, Kyle Happel, Joseph D. Schwartzman

Dartmouth Scholarship

We investigated the role of interleukin-17 (IL-17)/IL-17 receptor (IL-17R)-mediated signaling in the protective immunity against Toxoplasma gondii. IL-17R−/− mice developed a normal adaptive immunity against the parasite. However, increased mortality in the knockout animals can be attributed to a defect in the migration of polymorphonuclear leukocytes to infected sites during early infection.

Knowledge-Based Fault Detection Using Time-Frequency Analysis, Venkata S. Vongala

LSU Master's Theses

This work studies a fault detection method which analyzes sensor data for changes in their characteristics to detect the occurrence of faults in a dynamic system. The test system considered in this research is a Boeing-747 aircraft system and the faults considered are the actuator faults in the aircraft. The method is an alternative to conventional fault detection method and does not rely on analytical mathematical models but acquires knowledge about the system through experiments. In this work, we test the concept that the energy distribution of resolution than the windowed Fourier transform. Verification of the proposed methodology is carried …

Urban Yellow Fever Diffusion Patterns And The Role Of Micro-Environmental Factors In Disease Dissemination: A Temporal-Spatial Analysis Of The Memphis Epidemic Of 1878, William Brennan Arden

LSU Master's Theses

Most investigations that examine diffusion of disease through urban areas give relatively scant attention to the 'micro-environment.' Employing the many methods of macro-environmental analysis, most studies do not attempt to identify street-level or even residence-level temporal-spatial patterns of disease diffusion. As a result, the mechanisms that lead to diffusion on such small scales are left relatively undefined. There is no doubt that cumulatively these small-scale mechanisms contribute to the diffusion of disease over the urban environment. However, the level of contribution and the specific details of their dynamics remain unclear. This thesis investigated some of these unexplored areas by presenting …

Performance Based Switching Control For Single Input Linear Time Invariant Systems, Lalitha Srigouri Devarakonda

LSU Master's Theses

In the present research, we propose a new control strategy to improve the performance of a linear time invariant single input system. We consider a performance index that is dependent only on the controlled variable and try to improve it over that obtained when using a stable state feedback control. Since the control law depends on the performance of the controlled variable, we call it Performance Based Switching Control (PBSC). Switching between two state feedbacks is used to achieve this improvement in performance. The switching strategy combines the best features of both strategies. The switching surface is actually composed of …

Changing Face: The Evolution Of Chinese Women's Dress And Appearance, Xiaolan Wang

LSU Master's Theses

Women’s dress and appearance can reflect a lot about a civilized society. It is influenced by many factors as well. The dress and appearance of contemporary Chinese women have not been studied much by mass communication researchers. This paper, however, explored the factors that influence the development and evolution of contemporary Chinese women’s dress and appearance. It traced back from Dynastic China to Republican China and then to Mao’s red China to examine the historical and political influences imposed on the dress and appearance of Chinese women. Then, it used in-depth interviews to find out factors that influence women’s dress …

Effects Of Mental Rotation, Visual Aids And Training On Inspection Performance During Airport Baggage Inspection, Sunil Addepalli

LSU Master's Theses

Since 9/11, airport security has become an area of critical national security. The current study investigates the effect of mental rotation training and the presence of visual decision aids on inspection performance. Forty-eight participants were divided into two groups (Group A and Group B) of twenty-four each. Each group was provided with training on visual inspection, baggage screening and on using the software simulation of airport baggage inspection. Participants had to identify from images any object that cannot be allowed on a passenger plane and register a response by clicking one of the buttons, “Threat” or “No Threat”. Participants in …

Full Circle, Elizabeth Cowhig

LSU Master's Theses

My paintings are a result of a mainly intuitive process that evolves out of the combination of shape, color, and texture and originates from personal ideologies involving health phobias and religious beliefs. The imagery in the paintings is of biological origin, cells that fill up with matter, dense spheres that recall cancerous build up, the compositions and colors are inspired by Italian Renaissance paintings. The tangible is inserted into the realm of the ethereal.

The Battle Of New Orleans, Gregory Morris Thomas

LSU Master's Theses

America was not prepared for the War of 1812. The army and navy were so small they could not oppose Britain directly. American strategy in the first year called for the seizure of Canada. Multiple expeditions were complete failures resulting in military defeats and political embarrassment for President Madison. During the second year of the war there were more defeats for American forces, but some victories. These successes came mainly against Indians allied with the British along the frontier. The third and final year of the war started ominously. With Napoleons first abdication the wars in Europe seemed over, allowing …

The Role Of Calisto/Clindor/Theogenes In Tony Kushner's Adaptation Of The Illusion By Pierre Corneille A Production Thesis In Acting, Preston E. Davis

LSU Master's Theses

The role of Calisto/Clindor/Theogenes in Tony Kushner's adaptation of The Illusion by Pierre Corneille was selected as a thesis project in the fall semester, 2004. This thesis is a written record of the actor's interpretation of the character. The thesis includes a Character Analysis, Four Column Score of the Role and Personal notes on the role.

Comparing Calf Sex Ratio And Semen Sex Ratio Determined By Conventional Pcr, Tara Marie Taylor

LSU Master's Theses

Thirty-nine ejaculates from 8 Holstein bulls were collected. Straws of semen (n=750) were distributed among dairies in three states. Ten straws per ejaculate were sent to Louisiana State University (LSU) Dairy Improvement Center for conventional polymerase chain reaction (PCR) analysis. Spermatozoal DNA was extracted and PCR analysis was done using one primer set amplifying a single copy 125 base pair (bp) section of the Bos taurus factor IX (Christmas factor) precursor (found on the X chromosome) and another primer set amplifying a single copy section of the Bos taurus sex determining region Y protein (SRY) gene (found on the Y …

The 17 Kda Protein In Photosystem Ii, Purification And Interaction With The Photosystem, Glen Meades

LSU Master's Theses

The structural association of the spinach 17 kDa protein of photosystem II with other extrinsic and membrane-bound components of the photosystem was investigated by labeling the 17 kDa protein with the amino group-specific reagent N-hydrosuccinimidobiotin both on intact photosystem II membranes and free in solution. Following isolation of the biotinylated molecules, the modified 17 kDa protein was allowed to rebind at various molar ratios to photosystem II membranes lacking the 17 kDa protein. Differential binding of the biotinylated proteins compared to unmodified 17 kDa protein indicates steric or ionic interference due to added biotin moieties, impeding physical contact or shielding …

Experimental Investigation Of Stick-Slip Behavior In Granular Materials, Lynne E. Roussel

LSU Master's Theses

The mechanical behavior of granular materials is highly dependent on the arrangement of particles, particle groups, and associated pore spaces. Changes in the internal structure due to large deformation may cause changes in the mechanical behavior. The changes include: particle sliding, rolling, and interaction; shear band formation; and fabric anisotropy. During those changes, stick-slip behavior may take place between the granular particles. The objective of the thesis is to study the factors that influence the stick-slip behavior of granular materials. The influence of particle size, uniformity, confining pressure, density, and strain rate are investigated in this thesis. A series of …

The Effect Of Dietary Phosphorus Level And Phytase Supplementation On Growth Performance, Bone Breaking Strength, And Phosphorus Excretion In Broilers, Syrena Powell

LSU Master's Theses

This research was conducted to determine the effects of feeding different P levels with and without phytase supplementation on broiler growth performance, bone breaking strength (BBS), and P excretion. An experiment with 4 trials was conducted with 7,840 Ross x Ross straight run broilers. For each trial, 1,960 broilers were allotted on d 0 to 4 treatments with 7 replications per treatment with 70 broilers per replication. The broilers were fed a 4 period feeding program consisting of starter (0 to 14 d), grower (14 to 32 d), finisher (32 to 41 d), and withdrawal (41 to 50 d) periods. …

The Importance Of Size And Shape In Imprinted Polymers, Jason Campbell

LSU Master's Theses

The existence of shape selectivity in non-covalent molecularly imprinted polymers has been proven using molecular probes. A series of amines varying with different structural motifs and secondary amines with different sized side chains were imprinted, and binding evaluated by HPLC for each amine on polymers imprinted with similar amines. Trends in the binding relationships revealed two major contributions of cavity structure on selectivity afforded by molecularly imprinted polymers (MIPs). First, sterics play a dominant role in cases where a molecules structure is too big too fit into an imprinted site formed from a smaller template molecule. Second, molecular structures that …

Geologic Variability And Holocene Sedimentary Record On The Northern Gulf Of Mexico Inner To Mid-Continental Shelf, Triniti A. Dufrene

LSU Master's Theses

Sidescan Sonar, chirp sonar sub-bottom profiles, and grab samples were collected on the north-central Gulf of Mexico continental shelf as part of an interdisciplinary study mapping juvenile red snapper habitat. Demarcation of essential fish habitat for juvenile red snapper (Lutjanus campechansis) in the Gulf of Mexico is considered critical for effective management of this valuable species. The first goal of this study was to map and describe the geology of this region. The second goal was to attempt to relate variations in geology to juvenile red snapper abundance and distribution. Sidescan mosaics were created for ten polygons, ranging in size …

Sacred Trust: The Voluntary Removal And Reburial Of Human Remains From A Historic Cemetery In Louisiana, Christian Williamson

LSU Master's Theses

Members of the Randolph family, a prominent plantation family that has lived in Louisiana since the late eighteenth century, contacted a team of anthropologists from Louisiana State University to help recover thirteen individuals from St. Mary’s Cemetery in Bayou Goula, Louisiana. The cemetery had been abandoned since 1970, its graves overgrown with weeds and desecrated by vandals. Of the thirteen individuals recovered, three sets of remains did not have associated grave markers. These three were taken back to the lab and analyzed using standard forensic procedures. Documentary research on the history of the cemetery, the once associated church, and the …

Modification Of Ct Quality Assurance Phantom For Pet/Ct Alignment And Pet Resolution, Prashanth K. Nookala

LSU Master's Theses

Radiotherapy treatment planning utilizing PET and CT is rapidly gaining acceptance in oncology. A limiting factor of the dual modality is the PET/CT alignment. A small error in PET/CT alignment may result in giving large doses of radiation to healthy tissues as a result of poor treatment planning. For this purpose, regular quality assurance testing of PET/CT must be performed. Separate QA procedures and phantoms have been developed for the two different modalities. In particular, many existing phantoms cannot be used for both modalities, which is a requirement for evaluating PET/CT alignment. Our goal is to evaluate several existing phantom …

Neural Stem Cells As A Delivery Vector For Chemokine Expression In The Central Nervous System, Mark Winston Stalder

LSU Master's Theses

Increased expression of cytokines and chemokines in the central nervous system (CNS) is closely associated with the development of retroviral-induced neurological diseases such as HIV-associated dementia, as well as other neuropathologies such as Alzheimer’s Disease and Multiple Sclerosis. The specific functions of many of these pro-inflammatory factors have yet to be elucidated in the disease process, and it is unclear whether the nature of their effects is protective, pathogenic, or both. Additionally, current models of chemokine function have inherent limitations, with direct injection resulting in a brief response that doesn’t accurately represent the effects of chronic production, and transgenic mice …

Object Tracking Using Log-Polar Transformation, Saikiran Sri Thunuguntla

LSU Master's Theses

In this thesis, we use log-polar transform to solve object tracking. Object tracking in video sequences is a fundamental problem in computer vision. Even though object tracking is being studied extensively, still some challenges need to be addressed, such as appearance variations, large scale and rotation variations, and occlusion. We implemented a novel tracking algorithm which works robustly in the presence of large scale changes, rotation, occlusion, illumination changes, perspective transformations and some appearance changes. Log-polar transformation is used to achieve robustness to scale and rotation. Our object tracking approach is based on template matching technique. Template matching is based …

Spotted Sea Trout (Cynoscion Nebulosus) And Pinfish (Lagodon Rhomboides) Dietary Analysis According To Habitat Type, Micah Russell

LSU Master's Theses

The diets of a transitory fish (spotted sea trout, Cynoscion nebulosus) and a fish with presumed greater site-fidelity (pinfish, Lagodon rhomboides) were analyzed with respect to habitat. Sampling occurred in Barataria Bay, Louisiana between May 2003 and May 2004. Spotted sea trout were caught using gillnets, and pinfish were caught using baited fish traps. Each gear was used on three habitats: mud bottom, oyster shell, and marsh edge. In addition, sampling for spotted sea trout was repeated at three locations along a salinity gradient. A total of 175 spotted sea trout stomachs and 137 pinfish stomachs were examined. Seventeen prey …

Mining Picmet: 1997-2005 Papers Help You Track Management Of Technology Developments, Alan L. Porter, Robert J. Watts, Timothy R. Anderson

Engineering and Technology Management Faculty Publications and Presentations

PICMET is providing the abstracts from 1997 -- 2005 to enable you to "mine" the contents of these four conferences. This enables you to overview activity in the field of Management of Technology (MOT) and to identify specific research of interest.

Measuring The Changing Capabilities Of Computer Display Projectors Using Tfdea, Supachart Iamratanakul, Timothy R. Anderson, Lane Inman

Engineering and Technology Management Faculty Publications and Presentations

This paper applies technological forecasting using data envelopment analysis (TFDEA) to computer display projector (CDP) technology. The objective is to analyze the technological change CDP products. The results indicate that the rate of technological change for CDP technology is accelerating, which is consistent with an understanding of the industry. A methodological issue of infeasibility is described and methods for dealing with it are presented. Future work may extend to examine over additional years and product releases.

Flexibility – Examining An Underappreciated Motivation For Outsourcing With An Optimization Model In A Small E-Product Manufacturer, Asser Fayed, Timothy R. Anderson, David Fenwick

Engineering and Technology Management Faculty Publications and Presentations

Technology outsourcing has recently become a politically sensitive issue with proponents emphasizing longterm economic growth opportunities, and opponents pointing out immediate job losses. The underlying reason for outsourcing is often assumed to be the availability of cheaper labor outside the USA but this overlooks the possibility that companies may simply be seeking greater labor flexibility outside of US state and federal labor laws. This paper quantitatively tests a software company’s motivation to secure a flexible and adaptable labor pool. Although production lines located at multiple sites provide great flexibility for scheduling and costs because each site has its own local …

Do Maps Guide The Way To Npd Success? Theoretical And Practical Aspects Of Knowledge Mapping In Product Development, Antonie J, Jetter

Engineering and Technology Management Faculty Publications and Presentations

New product development success largely depends on the ability to combine newly acquired information on customer demands and technological options with knowledge that exists within the company. Project organization and high employee turnover, however, make it difficult to be informed about what knowledge is available within the company and to access it successfully. Knowledge maps, a popular concept in present knowledge management, offer a possible solution by ?guiding the way to knowledge?. Their purpose, structure and content varies greatly, as does their ability to capture different aspects of knowledge. This paper investigates the theoretical basis of different types of knowledge …

Methods For Correcting Topographically Induced Radiometric Distortion On Landsat Thematic Mapper Images For Land Cover Classification, David Michael Rosen

Geography Masters Research Papers

Satellite imagery is commonly used to study land-use, land-cover change in mountainous areas. Classification of land-cover types is particularly difficult in this type of terrain because topography affects the spectral response of surface features. Several techniques have been developed to help compensate for this topographic effect and to increase classification accuracy.

The purpose of this study is to compare topographic correction methods to determine which produces the most accurate results. Method 1 does not use any topographic correction, serving as a control. Method 2 is based on the Lambertian model, and uses topographical data as variables in an equation. Method …

Identification Of Recql1 As A Holliday Junction Processing Enzyme In Human Cell Lines, Gary Leroy, Robert Carroll, Saw Kyin, Masayuki Seki, Michael D. Cole

Dartmouth Scholarship

Homologous recombination provides an effective way to repair DNA double-strand breaks (DSBs) and is required for genetic recombination. During the process of homologous recombination, a heteroduplex DNA structure, or a ‘Holliday junction’ (HJ), is formed. The movement, or branch migration, of this junction is necessary for recombination to proceed correctly. In prokaryotes, the RecQ protein or the RuvA/RuvB protein complex can promote ATP-dependent branch migration of Holliday junctions. Much less is known about the processing of Holliday junctions in eukaryotes. Here, we identify RecQL1 as a predominant ATP-dependent, HJ branch migrator present in human nuclear extracts. A reduction in the …

Silencing Of Retrotransposons In Dictyostelium By Dna Methylation And Rnai, Markus Kuhlmann, Branimira E. Borisova, Markus Kaller, Pontus Larsson, Dirk Stach, Jianbo Na, Ludwig Eichinger, Frank Lyko, Victor Ambros, Fredrik Soderbom, Christian Hammann, Wolfgang Nellen

Dartmouth Scholarship

We have identified a DNA methyltransferase of the Dnmt2 family in Dictyostelium that was denominated DnmA. Expression of the dnmA gene is downregulated during the developmental cycle. Overall DNA methylation in Dictyostelium is ∼0.2% of the cytosine residues, which indicates its restriction to a limited set of genomic loci. Bisulfite sequencing of specific sites revealed that DnmA is responsible for methylation of mostly asymmetric C-residues in the retrotransposons DIRS-1 and Skipper. Disruption of the gene resulted in a loss of methylation and in increased transcription and mobilization of Skipper. Skipper transcription was also upregulated in strains that had genes encoding …