Digital Commons Network^™

Scattering Of Low Coherence Radiation And Applications, G. Popescu, A. Dogariu

Faculty Bibliography 2000s

In an effort to understand complex scattering phenomena, characteristics of optical waves such as polarization, angular spectrum, and temporal coherence have been extensively studied. In this article we will review several applications where the coherence properties of broad-band radiation offer unique sensing and diagnostic capabilities.

Evidence For The Regulatory Role Of The N-Terminal Helix Of Secretory Phospholipase A(2) From Studies On Native And Chimeric Proteins, Shan Qin, Abhay H. Pande, Kathleen N. Nemec, Xiaomei He, Suren A. Tatulian

Faculty Bibliography 2000s

The phospholipase A(2) (PLA(2)) enzymes are activated by binding to phospholipid membranes. Although the N-terminal alpha-helix of group I/II PLA(2)s plays an important role in the productive mode membrane binding of the enzymes, its role in the structural aspects of membrane-induced activation of PLA(2)s is not well understood. In order to elucidate membrane-induced conformational changes in the N-terminal helix and in the rest of the PLA(2), we have created semisynthetic human group IB PLA(2) in which the N-terminal decapeptide is joined with the C-13-labeled fragment, as well as a chimeric protein containing the N-terminal decapeptide from human group IIA PLA(2) …

Fluorescent Nanoparticle Probes For Cancer Imaging, Swadeshmukul Santra, Debamitra Dutta, Glenn A. Walter, Brij M. Moudgil

Faculty Bibliography 2000s

Optical imaging technique has strong potential for sensitive cancer diagnosis, particularly at the early stage of cancer development. This is a sensitive, non-invasive, non-ionizing (clinically safe) and relatively inexpensive technique. Cancer imaging with optical technique however greatly relies upon the use of sensitive and stable optical probes. Unlike the traditional organic fluorescent probes, fluorescent nanoparticle probes such as dye-doped nanoparticles and quantum dots (Qdots) are bright and photostable. Fluorescent nanoparticle probes are shown to be very effective for sensitive cancer imaging with greater success in the cellular level. However, cancer imaging in an in vivo setup has been recently realized. …

Fluorene-Based Fluorescent Probes With High Two-Photon Action Cross-Sections For Biological Multiphoton Imaging Applications, Katherine J. Schafer-Hales, Kevin D. Belfield, Sheng Yao, Peter K. Frederiksen, Joel M. Hales, Pappachan E. Kolattukudy

Faculty Bibliography 2000s

Two-photon fluorescence microscopy is a powerful tool for the study of dynamic cellular processes and live-cell imaging. Many commercially available fluorescent probes have been used in multiphoton-based imaging studies despite exhibiting relatively low two-photon absorption cross-section values in the tunability range of ultrafast Ti:sapphire lasers commonly used in multiphoton microscopy imaging. Furthermore, available fluorophores may be plagued with low fluorescence quantum yield and/or photoinstability (i.e., photobleaching) on exposure to the high peak power and photon density provided by the ultrafast laser source. To address the demand for better performing dyes, we prepare fluorophores tailored for multiphoton imaging. These fluorophores are …

Discrete Wave Propagation In Quadratically Nonlinear Media, Robert Iwanow

Electronic Theses and Dissertations

Discrete models are used in describing various microscopic phenomena in many branches of science, ranging from biology through chemistry to physics. Arrays of evanescently coupled, equally spaced, identical waveguides are prime examples of optical structures in which discrete dynamics can be easily observed and investigated. As a result of discretization, these structures exhibit unique diffraction properties with no analogy in continuous systems. Recently nonlinear discrete optics has attracted a growing interest, triggered by the observation of discrete solitons in AlGaAs waveguide arrays reported by Eisenberg et al. in 1998. So far, the following experiments involved systems with third order nonlinearities. …

The Effects Of A Single Exercise Bout On Plasma Leptin Concentration In Obese Males, George Kyriazis

Electronic Theses and Dissertations

Recent findings suggest that leptin may be regulated in response to abrupt changes in energy homeostasis. Therefore, it is conceivable that transient changes in energy balance induced by exercise may also regulate leptin synthesis and secretion. As such, we hypothesized that acute increases energy expenditure (i.e. exercise), may regulate leptin concentrations in obese individuals. Fifteen healthy obese males underwent either a single exercise session of moderate intensity (58.4 % ± 4.0 of VO2max) for 60 min (n=8), or served as controls (n=7). The exercise session elicited an energy expenditure of 567±80 Kcal. No significant changes in plasma leptin (pre 23.5± …

Effects Of Reduced Ras And Volume On Anaerobic Zone Performance For A Septic Wastewater Biological Phosphorous Removal System, Daniel Magro

Electronic Theses and Dissertations

Enhanced Biological Phosphorous Removal (EBPR) performance was found to be adequate with reduced Return Activated Sludge (RAS) flows (50% of available RAS) to the anaerobic tank and smaller than typical anaerobic zone volume (1.08 hours hydraulic retention time or HRT). Three identical parallel biological nutrient removal (BNR) pilot plants were fed with strong, highly fermented (160 mg/L VFAs), domestic/industrial wastewater from a full scale wastewater treatment facility (WWTF). The pilot plants were operated at 100%, 50%, 40% and 25% RAS (percent of available RAS) flows to the anaerobic tank with the remaining RAS to the anoxic tank. In addition, varying …

Compressed Pattern Matching For Text And Images, Tao Tao

Electronic Theses and Dissertations

The amount of information that we are dealing with today is being generated at an ever-increasing rate. On one hand, data compression is needed to efficiently store, organize the data and transport the data over the limited-bandwidth network. On the other hand, efficient information retrieval is needed to speedily find the relevant information from this huge mass of data using available resources. The compressed pattern matching problem can be stated as: given the compressed format of a text or an image and a pattern string or a pattern image, report the occurrence(s) of the pattern in the text or image …

Couple Play As A Predictor Of Couple Bonding, Physical Health And Emotional Health, Linda Vanderbleek

Electronic Theses and Dissertations

Traditional couple counseling research focused on why people end relationships, with research only recently addressing what factors contribute to relationship satisfaction and stability. Yet, throughout this research, minimal attention has been paid to the role of play in couple counseling. The research available on play in couple counseling had varied definitions of couple play and was not based on current couple counseling theory. The research and anecdotal data on couple play proposed a strong relationship between couple play and the factors that predict successful, long-term couple relationships, individual physical health and emotional health. This study applied current couple counseling theory …

Perceptions Of Research Administrators On The Value Of Certification, Thomas Joseph Roberts

Electronic Theses and Dissertations

The purpose of this study was to determine the perceived value of certification to research administration professionals and demographic characteristics. This study sought to determine whether those who have attained the Certificate in Research Administration (CRA) perceive a benefit to their careers and why most research administrators do not attempt certification. The primary research question studied is concerned with the relationship between perceived value of the CRA to research administration professionals and demographic characteristics. The survey instrument, Research Administrator Survey, was electronically distributed to 277 research administrators based in the Southeast region of the National Council of University Research Administrators …

Ritual, Myth, And Symbol In The Field Of Nuclear Posturing, Sean Noah Walsh

Electronic Theses and Dissertations

Since their inception, the actual use of nuclear weapons in conflict is extremely limited. There have been only two documented occurrences which were committed exclusively by the United States. By contrast, however, state posturing with nuclear weapons occurs with regularity transcending historical situations, national wealth, military power, or even the actual possession of nuclear weapons. Rationalist arguments that depict nuclear posturing as a means of deterrence appear insufficient given its tendency to unbalance perceptions of equilibrium, and the public nature in which it occurs. Instead, I examine nuclear posturing by the United States during the Cold War as a form …

Empirical Modeling Of A Marijuana Expectancy Memory Network In Children As A Function Of Age And Marijuana Use, Jacqueline Alfonso

Electronic Theses and Dissertations

The present investigation modeled the expectancy memory organization and likely memory activation patterns of marijuana expectancies of children across age and marijuana use. The first phase of the study surveyed 142 children to obtain their first associate to marijuana use. From their responses, the Marijuana Expectancy Inventory for Children and Adolescents (MEICA) was developed. The second phase of the study administered the MEICA to a second sample of 392 children to model marijuana expectancy organization and probable memory activation paths of marijuana users versus never-users. Results indicated that irrespective of age, adolescents who have used marijuana tend to emphasize positive-negative …

The Development Of A Fuzzy Model To Quantify Training Andeducational Factors And The Resulting Impact On Student Successand Lear, Chandre Butler

Electronic Theses and Dissertations

The utilization of fuzzy mathematical modeling for quantification of the quality of training and educational delivery is an innovative application that can result in measurable and repeatable results. This research was designed to apply proven quantification techniques and Industrial Engineering methodologies to a nontraditional environment. The outcomes of this research provide the foundation, initial steps and preliminary validation for the development of a systematic fuzzy theoretical model to be applied for the quantification of various areas within training and education delivery. The test bed for this methodology is Orange County Public School system, the twelfth largest school district in the …

Messenger Rna Profiling: A Prototype Method For Body Fluidand Tissue Identification, Jane Juusola

Electronic Theses and Dissertations

Conventional methods of body fluid identification use labor-intensive, technologically diverse techniques that are performed in a series, not parallel, manner and are costly in terms of time and sample. Furthermore, for some frequently encountered body fluids, such as saliva or vaginal secretions, no confirmatory technique exists. Terminally differentiated cells, such as blood lymphocytes or epithelial cells lining the oral cavity, have a unique pattern of gene expression, which is evinced by the presence and relative abundance of specific mRNA species. If the type and abundance of mRNAs can be determined in a stain or tissue sample recovered at the crime …

Non-Silicon Microfabricated Nanostructured Chemical Sensors For Electric Nose Application, Jianwei Gong

Electronic Theses and Dissertations

A systematic investigation has been performed for "Electric Nose", a system that can identify gas samples and detect their concentrations by combining sensor array and data processing technologies. Non-silicon based microfabricatition has been developed for micro-electro-mechanical-system (MEMS) based gas sensors. Novel sensors have been designed, fabricated and tested. Nanocrystalline semiconductor metal oxide (SMO) materials include SnO2, WO3 and In2O3 have been studied for gas sensing applications. Different doping material such as copper, silver, platinum and indium are studied in order to achieve better selectivity for different targeting toxic gases including hydrogen, carbon monoxide, hydrogen sulfide etc. Fundamental issues like sensitivity, …

Synthesis, Characterizations, And Evaluation Of New Reactive Two-Photon Absorbing Dyes For Two-Photon Excited Fluorescence Imaging Applications, Katherine J. Hales

Electronic Theses and Dissertations

Recent, cooperative advances in chemistry, biology, computing, photophysics, optics, and microelectronics have resulted in extraordinary developments in the biological sciences, resulting in the emergence of a novel area termed 'biophotonics'. The integrative and interdisciplinary nature of biophotonics cuts across virtually all disciplines, extending the frontiers of basic cellular, molecular, and biology research through the clinical and pharmaceutical industries. This holds true for the development and application of the novel imaging modality utilizing multiphoton absorption and its extraordinary contribution to recent advances in bioimaging. Intimately involved in the revolution of nonlinear bioimaging has been the development of optical probes for probing …

The Science And Religion Dialogue: Are Philosophical Foundations Necessary?, Michael Ventimiglia

Philosophy, Theology and Religious Studies Faculty Publications

William James is well-known for arguing that different words which describe the same practical state of affairs are, in fact, equivalent in meaning. This theory of meaning is one important strain of American pragmatism, the movement which remains America’s primary philosophical contribution to intellectual history, and it invites us to consider a unique perspective on the contemporary dialogue between science and religion. Specifically, it raises the question of the necessity of philosophical foundations when there is practical agreement.

This paper argues that when practical agreement can be reached there are certain purposes for which philosophical foundations can be strategically ignored. …

Reforming Child Protection: A Public Health Perspective, Marsha Garrison

Faculty Scholarship

No abstract provided.

Febrile Seizures. From Molecular Biology To Clinical Practice, Mohamad A. Mikati, Amal C. Rahi

Neurosciences

Febrile seizures occur between the age of 3 months and 5 years with a temperature of 38 degrees C or higher, and are either simple or complex. Eight gene loci have been identified to be associated with certain cases of autosomal dominant familial febrile seizures, and 12 genes have been associated with some of the familial epilepsy syndromes that can start with febrile seizures. The mutations and the protein products are known for only some of these 20 genes. The risk of recurrence of convulsions in a further febrile illness is on average 30%, and of developing epilepsy is on …

Book Review

Journal of Criminal Law and Criminology

No abstract provided.

Consciousness Eclipsed: Jacques Loeb, Ivan P. Pavlov, And The Rise Of Reductionistic Biology After 1900, R. Greenspan, B. Baars

CCRG Papers

No abstract provided.

The Role Of Consciousness In Memory, S. Franklin, B. Baars, U. Ramamurthy, M. Ventura

CCRG Papers

No abstract provided.

Medicare Should, But Cannot, Consider Cost: Legal Impediments To Sound Policy, Jacqueline R. Fox

Faculty Publications

No abstract provided.

Influence Of Oxygen Microenvironment On Microfluidic Glucose Sensor Performance, Chang-Soo Kim, Jongwon Park

Electrical and Computer Engineering Faculty Research & Creative Works

We propose a novel method to overcome significant problems of baseline drift and sensitivity degradation in amperometric biosensors based on oxidase enzyme reactions. A novel glucose microsensor with a built-in electrochemical oxygen manipulation microsystem is introduced to demonstrate three novel functionalities; one-point in situ self-calibration (zero-point), broadening of dynamic range and increase in sensitivity. The influence of electrochemically generated oxygen microenvironment on the sensor output within a fluidic structure is investigated.

A Comparison Of Pso And Backpropagation For Training Rbf Neural Networks For Identification Of A Power System With Statcom, Salman Mohagheghi, Ganesh K. Venayagamoorthy, Yamille Del Valle, Ronald G. Harley

Electrical and Computer Engineering Faculty Research & Creative Works

Backpropagation algorithm is the most commonly used algorithm for training artificial neural networks. While being a straightforward procedure, it suffers from extensive computations, relatively slow convergence speed and possible divergence for certain conditions. The efficiency of this method as the training algorithm of a radial basis function neural network (RBFN) is compared with that of particle swarm optimization, for neural network based identification of a small power system with a static compensator. The comparison of the two methods is based on the convergence speed and robustness of each method.

Rich Mesic Forests: Edaphic And Physiographic Drivers Of Community Variation In Western Massachusetts, J. Bellemare, G. Motzkin, D. R. Foster

Biological Sciences: Faculty Publications

Rich Mesic Forest, a Northeastern variant of the species-rich Mixed Mesophytic Forest association of eastern North America, is an Acer saccharum-dominated forest type typically associated with calcareous bedrock and nutrient-rich, mull soils. Rich Mesic Forest (RMF) is a priority for conservation in the Northeast due to its limited areal extent, high plant species richness, and numerous rare taxa, yet the community characteristics and environmental correlates of this forest type are incompletely understood. This study undertook a quantitative classification of RMF of the northeastern edge of the Berkshire Plateau in western Massachusetts. Cluster analysis of data from ten sites identified two …

A General Recurrent Neural Network Approach To Model Genetic Regulatory Networks, Xiao Hu, Anne M. Maglia, Donald C. Wunsch

Biological Sciences Faculty Research & Creative Works

There is an urgent need for tools to unravel the complex interactions and functionalities of genes. As such, there has been much interest in reverse-engineering genetic regulatory networks from time series gene expression data. We use an artificial neural network to model the dynamics of complicated gene networks and to learn their parameters. The positive and negative regulations of genes are defined by a weight matrix, and different genes are allowed to have different decaying time constants. We demonstrate the effectiveness of the method by recreating the SOS DNA Repair network of Escherichia coli bacterium, previously discovered through experimental data.

2005 Lynn University Women's Softball Media Guide, Lynn University Athletics

Athletics Media Guides

The 2005 Lynn University Softball Media Guide is a production of the Lynn University Office of Sports Information.

A Survey Of Herpetofaunal Diversity In A Longleaf Pine Forest Ecosystem, Jeffrey D. Camper

Journal of the South Carolina Academy of Science

No abstract provided.

Punishment And Rehabilitation Views Of Social Work Majors And Non-Social Work Students: An Exploratory Study, Eric G. Lambert, Sudershan Pasupuleti, Reva I. Allen

Journal of the South Carolina Academy of Science

No abstract provided.