Digital Commons Network^™

Post-Translational Regulation Of Adipose Differentiation-Related Protein By The Ubiquitin/Proteasome Pathway, John Tansey

Chemistry Faculty Scholarship

Adipose differentiation-related protein (ADRP) is localized to lipid droplets in most mammalian cells. ADRP, proposed to regulate
fatty acid mobilization and lipid droplet formation, is linked to lipid accumulation in foam cells of human atherosclerotic
lesions. In this report, we show that ADRP protein accumulates in Chinese hamster ovary fibroblastic cells cultured in the
presence of oleic acid but is destabilized when fatty acid sources are removed from culture serum. The latter effect was blocked
by the proteasome inhibitor MG132, whereas inhibitors of other proteolytic processes were ineffective. Pulse-chase experiments
confirmed that ADRP degradation is inhibited by MG132. Conditions that …

Current, August 22, 2005, University Of Missouri-St. Louis

Current (2000s)

No abstract provided.

The Murray Ledger And Times, August 22, 2005, The Murray Ledger And Times

The Murray Ledger & Times

No abstract provided.

Portable Probes To Measure Electrical Conductivity And Soil Quality In The Field, S.L. Arnold, John W. Doran, James S. Schepers, Brian J. Wienhold, Daniel Ginting, Brigid Amos, S. Gomes

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

Soil electrical conductivity (EC) is a useful indicator in managing agricultural systems, but tools for convenient and inexpensive measurements in the field are generally lacking. Handheld conductivity probes were designed to evaluate in-field naturally occurring and human-induced total soluble electrolyte levels in soil and water. The probes were used to survey and monitor EC in the field and to assess soil and water quality as related to environmental stability and sustainable food production. A pencil-sized 16-cm probe (PP) was connected to a handheld Hanna (DiST WP 4) conductivity meter, resulting in an economical, compact, and easy to use device. The …

Bjc Today

BJC Today

No abstract provided.

Lanthorn, Vol. 40, No. 02, August 22, 2005, Grand Valley State University

Volume 40, July 14, 2005 - June 15, 2006

Lanthorn is Grand Valley State's student newspaper, published from 1968 to the present.

August 22, 2005, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.

Computing The Total Sample Size When Group Sizes Are Not Fixed, Mithat Gonen

Memorial Sloan-Kettering Cancer Center, Dept. of Epidemiology & Biostatistics Working Paper Series

This article is concerned with computing the total sample size required for a two-sample comparison when the sizes of the two groups to be compared cannot be fixed in advance. This is frequently encountered when group membership depends on a variable which is observable only after the subject is enrolled to the study, such as a genetic or a biological marker. The most common way of circumventing this problem is assuming a fixed number for the prevalence of the condition that will determine the group membership and compute the required sample size conditionally. In this article this practice is formalized …

Day 3: Friday, 19 August 2005: Section 7 Consultation, Susan Linner, Leslie Elwood, Steve Culver

Endangered Species Act Congressional Field Tour (August 17-19)

10 pages (includes color illustrations and map).

Contains references.

Day 3: Friday, 19 August 2005: Habitat Conservation Plans, Susan Linner, Anne Ruggles, Anne Winans

Endangered Species Act Congressional Field Tour (August 17-19)

5 pages (includes illustration).

Contains references.

Survival Point Estimate Prediction In Matched And Non-Matched Case-Control Subsample Designed Studies, Annette M. Molinaro, Mark J. Van Der Laan, Dan H. Moore, Karla Kerlikowske

U.C. Berkeley Division of Biostatistics Working Paper Series

Providing information about the risk of disease and clinical factors that may increase or decrease a patient's risk of disease is standard medical practice. Although case-control studies can provide evidence of strong associations between diseases and risk factors, clinicians need to be able to communicate to patients the age-specific risks of disease over a defined time interval for a set of risk factors.

An estimate of absolute risk cannot be determined from case-control studies because cases are generally chosen from a population whose size is not known (necessary for calculation of absolute risk) and where duration of follow-up is not …

Red Rock Desert Learning Center: The Vision, Red Rock Desert Learning Center

Oliver Ranch Project

To instill stewardship and respect by increasing knowledge and understanding of the Mojave Desert ecosystems and cultures through a unique experiential discovery program.

Two Regions In Peru Legalize Coca-Leaf Cultivation, Ladb Staff

NotiSur

No abstract provided.

Mechanisms Underlying The Production Of Carapace Vibrations And Associated Waterborne Sounds In The American Lobster, Homarus Americanus, Winsor H. Watson Iii, Heidi Pye Henninger

Jackson Estuarine Laboratory

American lobsters produce carapace vibrations, which also lead to waterborne acoustic signals, by simultaneously contracting the antagonistic remotor and promotor muscles located at the base of the second antenna. These vibrations have a mean frequency of 183.1 Hz (range 87–261 Hz), range in duration from 68 to 1720 ms (mean 277.1 ms) and lead to waterborne sounds of similar frequencies. Lobsters most often produce these signals using only one pair of muscles at a time and alternate between the muscles of the left and right antennae when making a series of vibrations. Occasionally, they vibrate their carapace by simultaneously contracting …

Day 2: Thursday, 18 August 2005: Colorado Native Aquatic Species Restoration Program, Dave Schnoor

Endangered Species Act Congressional Field Tour (August 17-19)

6 pages (includes illustrations).

Contains one reference.

Day 2: Thursday, 18 August 2005: Upper Colorado River Endangered Fish Recovery Program, Bob Muth, Tom Pitts, Dan Luecke

Endangered Species Act Congressional Field Tour (August 17-19)

58 pages (includes illustrations and maps).

Contains references.

Day 2: Thursday, 18 August 2005: Canada Lynx Reintroduction, Gary Skiba, Rob Edward, Bonnie Kline

Endangered Species Act Congressional Field Tour (August 17-19)

5 pages (includes some color illustrations and maps).

Contains references.

Smith V. Mullarkey

Colorado Supreme Court Records and Briefs Collection

No abstract provided.

Crosslinked Chitosan: Its Physical Properties And The Effects Of Matrix Stiffness On Chondrocyte Cell Morphology And Proliferation, Anuradha Subramanian, Hsin-Yi Lin

Papers in Biotechnology

Chitosan [<(1-4)-2 amino-2-deoxy-d-glucose], the natural polyaminosaccharide derived from N-deacetylation of chitin [<(1-4)-2 acetamide-2-deoxy-d-glucose], has been shown to possess attractive biological and cell interactive properties. Recently chitosan and chitosan analogs have also been shown to support the growth and continued function of chondrocytes. In the present study, chitosan substrates are crosslinked with a func-tional diepoxide (1,4 butanediol diglycidyl ether) to alter its mechanical property, and the viability and proliferation of the canine articular chondrocytes seeded on the crosslinked surface are further assayed. Of interest is the impact of substrate stiffness on the growth and proliferation of articular canine chondrocytes. Cross linked scaffolds were also sub-jected to degradation by chitosanase to examine the impact of cross linking on enzyme- assisted degradation. The hydrophilicity and compression modulus of the crosslinked sur-faces were measured via contact-angle measurements and compression tests, respec-tively. Scanning electron microscopy (SEM) and fluorescent staining were used to ob-serve the proliferation and morphology of chondrocyte cells on noncrosslinked and crosslinked surfaces. The crosslinked chitosan was found to be nontoxic to chondrocytes and more hydrophilic. Its compression modulus and stiffness increased, which may im-prove the scaffold resistance to wear and in vivo shrinkage once implanted. The in-creased stiffness also seemed to serve as an additional mechanical stimulus to promote chondrocyte growth and proliferation. The cell morphology on crosslinked scaffolds seen by SEM and fluorescent stain was the typical chondrocytic rounded shape. The method proposed provides a nontoxic way to increase the mechanical strength of the chitosan scaffolds.

Animal Virus Replication And Rnai-Mediated Antiviral Silencing In Caenorhabditis Elegans, R. Lu, M. Maduro, F. Li, H. W. Li, G. Broitman-Maduro, W. X. Li, S. W. Ding

Faculty Publications

The worm Caenorhabditis elegans is a model system for studying many aspects of biology, including host responses to bacterial pathogens, but it is not known to support replication of any virus. Plants and insects encode multiple Dicer enzymes that recognize distinct precursors of small RNAs and may act cooperatively. However, it is not known whether the single Dicer of worms and mammals is able to initiate the small RNA-guided RNA interference (RNAi) antiviral immunity as occurs in plants and insects. Here we show complete replication of the Flock house virus (FHV) bipartite, plus-strand RNA genome in C. elegans. We show …

Central Florida Future, Vol. 38 No. 01, August 18, 2005

Central Florida Future

Proposed football stadium entrenched in debate between north and south: Residents continue to request change in location to avoid traffic problems in neighborhoods surrounding campus; Welcome back: as the new academic year begins so does the quest of many students to find enrichment both academically and socially; Planning for future important choice for college students: When it comes to retirement it's never a bad idea to get started early; Freshmen link with campus leaders: SGA President kicks off a week of field trips fun for new freshmen students; Aruban murder suspect wears UCF shirt on TV.

The George-Anne, Georgia Southern University

The George-Anne

• Bomb Destroyed Inside Local Apartment
• Campus News
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• Opinion
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• Variety
• Roll Call

Electronic Transport Imaging In A Multiwire Sno2 Chemical Field-Effect Transistor Device, Sergei V. Kalinin, J. Shin, S. Jesse, D. Geohegan, A. P. Baddorf, Y. Lilach, M. Moskovits, A. Kolmakov

Publications

The electronic transport and the sensing performance of an individual SnO₂ crossed-nanowires device in a three-terminal field-effect transistor configuration were investigated using a combination of macroscopic transport measurements and scanning surface-potential microscopy (SSPM). The structure of the device was determined using both scanning electron- and atomic force microscopy data. The SSPM images of two crossed one-dimensional nanostructures, simulating a prototypical nanowire network sensors, exhibit large dc potential drops at the crossed-wire junction and at the contacts, identifying them as the primary electroactive elements in the circuit. The gas sensitivity of this device was comparable to those of sensors formed …

Day 1: Wednesday, 17 August 2005: Introduction, Mark Squillace

Endangered Species Act Congressional Field Tour (August 17-19)

5 pages.

Contains references.

Day 1: Wednesday, 17 August 2005: Science And The Esa, Joy Nicholopoulos, William Lewis

Endangered Species Act Congressional Field Tour (August 17-19)

43 pages (includes illustrations and map).

Contains references.

Day 1: Wednesday, 17 August 2005: Biodiversity And Critical Habitat, Charles Bedford, Federico Cheever, Tim Sullivan

Endangered Species Act Congressional Field Tour (August 17-19)

6 pages (includes color illustration).

Contains references.

Antitrypanosomal, Antileishmanial, And Antimalarial Activities Of Quaternary Arylalkylammonium 2-Amino-4-Chlorophenyl Phenyl Sulfides, A New Class Of Trypanothione Reductase Inhibitor, And Of N-Acyl Derivatives Of 2-Amino-4-Chlorophenyl Phenyl Sulfide, Seheli Parveen, M. O. Faruk Khan, Susan E. Austin, Simon L. Croft, Vanessa Yardley, Peter Rock, Kenneth T. Douglas

Pharmaceutical Science and Research

Quaternization of the nitrogen atom of 2-amino-4-chlorophenyl phenyl sulfide analogues of chlorpromazine improved inhibition ∼40-fold (3′,4′-dichlorobenzyl-[5-chloro-2-phenylsulfan- ylphenylamino)-propyl]-dimethylammonium chloride inhibited trypanothione reductase from Trypanosoma cruzi with a linear competitive Ki value of 1.7 ( 0.2 µM). Molecular modelling explained docking orientations and energies by: (i) involvement of the Z-site hydrophobic pocket (roughly bounded by F396′, P398′, and L399′), (ii) ionic interactions for the cationic nitrogen with Glu-466′ or -467′. A series of N-acyl-2-amino-4-chlorophenyl sulfides showed mixed inhibition (Ki, Ki′ ) 11.3-42.8 µM). The quaternized analogues of the 2-chlorophenyl phenylsulfides had strong antitrypanosomal and antileishmanial activity in vitro against T. bruceirhodesiense STIB900, …

Ua3/9/5 Conservation Reserve Enhancement Program (Crep), Wku President's Office

WKU Administration Documents

Talking points used by WKU president Gary Ransdell regarding WKU's partnering with Conservation Reserve Enhancement Program.

Migration Ecology And Distribution Of King Eiders, Laura Marie Phillips

Biological Sciences

Alaskan-breeding king eiders (Somateria spectabilis) disperse from nesting areas on the Arctic Coastal Plain and move through the Beaufort Sea to wing molt and winter locations in remote areas of the Bering Sea. Knowledge of king eider distribution outside the breeding period is critical to provide regulatory agencies with opportunities to minimize potential negative impacts of resource development. To characterize the nonbreeding distribution of king eiders, we collected location data of 60 individuals over two years from satellite telemetry. During post-breeding migration, male king eiders had much broader use areas in the Alaskan Beaufort Sea than female eiders. Chronology of …

Breeding Ecology Of White-Winged Scoters On The Yukon Flats, Alaska, David Elliot Safine

Biological Sciences

Breeding bird surveys indicate a long-term decline in the numbers of scoters (Melanitta sp.) in North America. My objectives were to estimate survival of nests, ducklings, and adult female White-winged Scoters (Melanitta fusca) breeding on the Yukon Flats National Wildlife Refuge, Alaska, 2002-2004, within their primary breeding range. I measured habitat variables at nest sites and random sites in the study area to characterize nest habitat selection, and investigated breeding incidence with a laboratory analysis of circulating concentrations of the plasma yolk precursors vitellogenin (VTG) and very-low density lipoprotein (VLDL). The low hen and nest survival rates I observed combined …