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Exploring Marine Biotoxins Using Analytical Techniques Based On Mass Spectrometry, Mónica Fernández Amandi

Theses

The impact of phycotoxins on human and animal health is of important concern for worldwide authorities and the scientific community. Domoic acid (DA) is a neurotoxin produced by phytoplankton {Pseudonitzchia spp.). It enters the food chain through the consumption of shellfish that feed on toxic diatoms. DA has been responsible for several outbreaks affecting humans and animals all around the world. Yessotoxin (YTX) is produced by dinoflagellate species {Protoceratiuni reticulatum) which are globally distributed. Its toxicity is low when ingested orally. However, the co-extraction of YTX with diarrhetic shellfish poisoning (DSP) toxins, derives false positives when the mouse bioassay is …

Representing Children In Families, Bruce A. Green, Annette R. Appell

Faculty Scholarship

No abstract provided.

Catalog Denison University 2005-2006

Denison University Catalogs

Denison University Course Catalog 2005-2006

Medical Symptoms Associated With Tobacco Smoking With And Without Marijuana Abuse Among Crack Cocaine-Dependent Patients., Ashwin A. Patkar, Vikas Batra, Paolo Mannelli, Sarah Evers-Casey, Michael J. Vergare, Frank T. Leone

Department of Psychiatry and Human Behavior Faculty Papers

Despite the widespread use of tobacco and marijuana by cocaine abusers, it remains unclear whether combined tobacco and marijuana smoking is more harmful than tobacco smoking alone in cocaine abusers. We investigated the differences in medical symptoms reported among 34 crack cocaine abusers who did not smoke tobacco or marijuana (C), 86 crack cocaine abusers who also smoked tobacco (C + T), and 48 crack abusers who smoked both tobacco and marijuana (C + T + M). Medical symptoms were recorded using a 134-item self-report instrument (MILCOM), and drug use was assessed using the Addiction Severity Index (ASI). After controlling …

Demonstration Of Toxicity To Fish And To Mammalian Cells By Pfiesteria Species: Comparison Of Assay Methods And Strains, Joann M. Burkholder, Andrew S. Gordon, Peter D. Moeller, J. Mac Law, Kathryn J. Coyne, Alan J. Lewitus, John S. Ramsdell, Harold G. Marshall, Nora J. Deamer, S. Craig Cary, Jason W. Kempton, Steven L. Morton, Parke A. Rublee

Biological Sciences Faculty Publications

Toxicity and its detection in the dinoflagellate fish predators Pfiesteria piscicida and Pfiesteria shumwayae depend on the strain and the use of reliable assays. Two assays, standardized fish bioassays (SFBs) with juvenile fish and fish microassays (FMAs) with larval fish, were compared for their utility to detect toxic Pfiesteria. The comparison included strains with confirmed toxicity, negative controls (noninducible Pfiesteria strains and a related nontoxic cryptoperidiniopsoid dinoflagellate), and P. shumwayae strain CCMP2089, which previously had been reported as nontoxic. SFBs, standardized by using toxic Pfiesteria (coupled with tests confirming Pfiesteria toxin) and conditions conducive to toxicity expression, reliably detected …

Mechanical Properties Of The Integument Of The Common Gartersnake, Thamnophis Sirtalis (Serpentes: Colubridae), Gabriel Rivera, Alan H. Savitzky, Jeffrey A. Hinkley

Biological Sciences Faculty Publications

The evolution of the ophidian feeding mechanism has involved substantial morphological restructuring associated with the ability to ingest relatively large prey. Previous studies examining the morphological consequences of macrophagy have concentrated on modifications of the skull and cephalic musculature. Although it is evident that macrophagy requires highly compliant skin, the mechanical properties of the ophidian integument have received limited attention, particularly in the context of feeding. We examined mechanical properties of skin along the body axis in Thamnophis sirtalis (Colubridae). Data were collected from tensile tests and were analyzed using a multivariate analysis of variance (MANOVA) and post-hoc multiple comparison …

The Many Faces Of Overcriminalization: From Morals And Mattress Tags To Overfederalization, Sara Sun Beale

Faculty Scholarship

No abstract provided.

Recoupment: Apples, Oranges And Fruit Basket Turnover, David G. Epstein

Law Faculty Publications

fiscal years and deducted the overpayment from its payments to H during that year. The fiscal year 2000 was also the year that H filed for Chapter 11. H filed an adversary proceeding against US contending that the deductions within four months before H's bankruptcy filing were voidable preferential transfers and that US's deductions after the bankruptcy filing were in violation of the automatic stay. The bankruptcy judge, the district court judge, and a unanimous appellate court panel looked to the law of recoupment to hold that US's reduction of payments was neither a preferential transfer nor a violation of …

Coffee To Go! Modeling Thermoclines In Multivariable Calculus, Andrea Bruder, Brynja R. Kohler

Mathematics and Statistics Faculty Publications

While mathematical modeling is an integral process in applied mathematics, students rarely encounter genuine modeling opportunities in their calculus courses. Here we introduce a laboratory experience as a natural starting point for calculus students to investigate multivariable functions. A layered system of coffee and milk serves as a physical model for temperature gradients in lakes or the atmosphere, where temperature depends on both a temporal and spatial variable. Students create, observe, and collect temperature data of their own, graph the data, and develop mathematical models to fit the data. We require students to write a report about their findings. This …

Student Expression In The Age Of Columbine: Securing Safety And Protecting First Amendment Rights, David L. Hudson Jr.

Law Faculty Scholarship

"Student Expression in the Age of Columbine" is one in an ongoing series of First Reports, published by the First Amendment Center, on major First Amendment issues of our time.

Recoupment: Apples, Oranges And Fruit Basket Turnover, David G. Epstein, Jonathan A. Nockels

SMU Law Review

No abstract provided.

Jury Of Our Peers: An Unfulfilled Constitutional Promise, Robert C. Walters, Michael D. Marin, Mark Curriden

SMU Law Review

No abstract provided.

A Troubling Equation In Contracts For Government Funded Scientific Research: "Sensitive But Unclassified" = Secret But Unconstitutional, Leslie Gielow Jacobs

McGeorge School of Law Scholarly Articles

No abstract provided.

Ab Initio : A New Concept In Engineering Education, A History Of The Design, Creation And Implementation Of A New School Of Engineering In Richmond, Virginia (1990-2000), Henry A. Mcgee Jr.

VCU University History Books

Dr. Henry A. McGee, Jr., Founding Dean Emeritus of the School of Engineering at Virginia Commonwealth University, chronicles the history of the School of Engineering through his term as Founding Dean, 1994–1999. McGee details the process of creating a program aimed to balance innovation and entrepreneurship.

A Legal Framework For Preventing Cardiovascular Diseases, Wendy Collins Perdue

Law Faculty Publications

Cardiovascular diseases are major contributors to death, disability, disparities, and reduced quality of life in the United States. Successful prevention and control of these diseases requires a comprehensive approach applied across multiple public health settings and in all life stages. Individual lifestyle and behavior change, as well as the broader social, environmental, and policy changes that enable healthy lifestyles, are necessary. Legal strategies can be powerful tools in this endeavor. This review presents seven such strategies applicable at the federal, state, and local levels that can be employed by healthcare providers, public health practitioners, legislators, and other policymakers. They include …

U.S.A. & France: I Love You ~ Neither Do I, Dirk Chatelain, Patti Vannoy, Rachael Seravalli, Kevin Abourezk, Erin Hilsabeck, Laura Schreier, Alyssa Schukar

College of Journalism and Mass Communications: Student Media

The Reporting
The Relationship by Dirk Chatelain
The History by Patti Vannoy
The American Inparis by Dirk Chatelain
The Expats by Rachael Seravalli
The Native Love by Kevin Abourezk
The Parisian Wild West by Kevin Abourezk
The Montauban by Kevin Abourezk
The Tourists by Erin Hilsabeck
The Art Capital by Erin Hilsabeck
The Famous Book Store by Laura Schreier
The Images by Alyssa Schukar
The Pop Culture by Laura Schreier
The Small Screen by Rachael Seravalli
The Veil Debate by Patti Vannoy
The Immigrants by Dirk Chatelain
The Rights Of Women by Patti Vannoy
The European Leader by Erin Hilsabeck …

Ethnicity And Gender Related Differences In Extended Intraesophageal Ph Monitoring Parameters In Infants: A Retrospective Study, Dena Nazer, Ronald Thomas, Vasundhara Tolia

Wayne State University Associated BioMed Central Scholarship

Abstract

Background

Gastroesophageal reflux disease (GERD) is believed to be more common in adult males as compared to females. It also has been shown in adults to be more common in Caucasians. We wanted to determine ethnicity and gender related differences for extended pH monitoring parameters in infancy.

Methods

Extended pH monitoring data (EPM) from infants <1 year of age were reviewed. Results were classified in two groups, as control and Gastroesophageal reflux disease (GERD) group based on the reflux index (RI). The GERD group had RI of equal to or more than 5% of total monitoring period. The parameters of RI, total number of episodes of pH < 4, and the number of episodes with pH < 4 lasting more than 5 minutes were compared by genders and by ethnic groups, Caucasians and African American (AA).

Results

There were 569 infants, 388 controls, 181 with GERD (320 males, 249 females; 165 Caucasians, 375 AA). No statistical difference in EPM parameters was detected between genders in both groups. However, Caucasian infants had a significantly higher incidence of GERD than AA infants …

Correlation Of Same-Visit Hba1c Test With Laboratory-Based Measurements: A Metronet Study, Kendra L. Schwartz, Joseph C. Monsur, Monina G. Bartoces, Patricia A. West, Anne Neale

Wayne State University Associated BioMed Central Scholarship

Abstract

Background

Glycated hemoglobin (HbA1c) results vary by analytical method. Use of same-visit HbA1c testing methodology holds the promise of more efficient patient care, and improved diabetes management. Our objective was to test the feasibility of introducing a same-visit HbA1c methodology into busy family practice centers (FPC) and to calculate the correlation between the same-visit HbA1c test and the laboratory method that the clinical site was currently using for HbA1c testing.

Methods

Consecutive diabetic patients 18 years of age and older having blood samples drawn for routine laboratory analysis of HbA1c were asked to provide a capillary blood sample for …

Dean Lindsey Cowen Business Law Lecture: Justified Monopolies: Regulating Pharmaceuticals And Telecommunications, Richard A. Epstein

Case Western Reserve Law Review

No abstract provided.

Undergraduate Catalog 2005-2006, University Of North Florida

UNF Course Catalogs

No abstract provided.

Strategic Management For Economic Development: Remaking The Singapore 'Model', Caroline Yeoh, Wilfred Pow Ngee How

Research Collection Lee Kong Chian School Of Business

The dynamics of international economic competition have far-reaching policy implications for both developing and developed countries. Established industrial and trade policy regimes in most countries are under tremendous strain, and this applies even to the dynamic Newly Industrialising Economies (NIEs). The outward-oriented development strategies of the Asian NIEs, which once seemed unbeatable, have run up against protectionist barriers in the developed countries, and increasingly, against competitive pressures from other up and coming developing countries. Governments in these NIEs have had to re-examine accustomed policies and strategies, and search for alternative strategies and programs, in order to re-position their economies for …

Residual Life Distributions From Component Degradation Signals: A Bayesian Approach, Nagi Gebraeel, Mark Lawley, Rong Li, Jennifer Ryan

Research Collection Lee Kong Chian School Of Business

No abstract provided.

Helicobacter Pylori Infection In Havana, Cuba. Prevalence And Caga Status Of The Strains, Beatriz Gutiérrez, Teresita Vidal, Carlos Ernesto Valmaña, Christine Camou-Juncas, Adriana Santos, Françis Mégraud, Nery González, Ibrahim Leonard, Rolando Martínez, Osvaldo Díaz-Canel, Manuel Paniagua, María Del Pilar Escobar, George L. Mendz

Medical Papers and Journal Articles

There is a great paucity of information about Helicobacter pylori infection in the countries of the Caribbean basin. Almost no studies have been performed to determine the prevalence, antibiotic resistance or virulence factors of the bacterium. To measure the prevalence of H. pylori infection among patients attending endoscopy in three clinics in Havana, Cuba, to evaluate clarithromycin resistance, and to determine the cagA status of the strains obtained. Endoscopy was performed and biopsies were obtained from 117 successive patients attending the Institute of Oncology, the Institute of Gastroenterology, and the Calixto Garcia Hospital in Havana, Cuba. Biopsies were maintained at …

The Presence Of Plasmodium Falciparum Gametocytes In Human Blood Increases The Gravidity Of Anopheles Gambiae Mosquitoes, Heather M. Ferguson, Louis C. Gouagna, Peter Obare, Andrew F. Read, Hamza Babiker, John Githure, John C. Beier

All Peer-Reviewed Publications

We conducted a field study in an area of endemic malaria transmission in western Kenya to determine whether mosquitoes that feed on gametocyte-infected blood but do not become infected have reduced or enhanced fecundity in comparison to mosquitoes fed on uninfected blood. Fifteen paired membrane-feeding experiments were conducted in which two strains of Anopheles gambiae mosquitoes were simultaneously fed on either Plasmodium falciparum-infected blood from children or uninfected control blood from adults. The presence of noninfecting gametocytes in blood increased the probability that An. gambiae would produce eggs after one blood meal by sixfold (odds ratio for control relative to …

Prime-Boost Vaccination With Plasmid And Adenovirus Gene Vaccines Control Her2/Neu+ Metastatic Breast Cancer In Mice, Xiaoyan Wang, Jian-Ping Wang, Xiao-Mei Rao, Janet E Price, Heshan S Zhou, Lawrence B Lachman

Faculty, Staff and Student Publications

INTRODUCTION: Once metastasis has occurred, the possibility of completely curing breast cancer is unlikely, particularly for the 30 to 40% of cancers overexpressing the gene for HER2/neu. A vaccine targeting p185, the protein product of the HER2/neu gene, could have therapeutic application by controlling the growth and metastasis of highly aggressive HER2/neu+ cells. The purpose of this study was to determine the effectiveness of two gene vaccines targeting HER2/neu in preventive and therapeutic tumor models.

METHODS: The mouse breast cancer cell line A2L2, which expresses the gene for rat HER2/neu and hence p185, was injected into the mammary fat pad …

Predatory Mites Associated With Tetranychus Evansi Baker & Pritchard (Acari: Tetranychidae) On Native Solanaceous Plants Of Coastal Pernambuco State, Brazil, Alexsandra A. Rosa, Manoel G.C. Gondim, Komi K.M. Fiaboe, Gilberto J. De Moraes, Knapp Markus

All Peer-Reviewed Publications

The occurrence of the tomato red spider mite (Tetranychus evansi Baker & Pritchard) and predatory mites on four of the most abundant native solanaceous plants in coastal Pernambuco, Brazil, was evaluated. Monthly samples were collected from mid September 2002 to late May 2003 in Aliança, Carpina, Camaragibe, Goiana, Igarassu and Recife. A total of 5,485 mites of more than 27 species were found, of which the most common were the phytophagous species T. evansi and Brevipalpus phoenicis (Geijskes) (Tenuipalpidae), and the predaceous species Asca sp. (Ascidae), Phytoseius guianensis De Leon and Paraphytoseius orientalis (Narayanan, Kaur & Ghai) (both Phytoseiidae). Negative …

Dunks And Drunks: Depictions Of Drug And Alcohol Use Among High School Athletes In Film, Peter S. Finley, Laura L. Finley

Essays in Education

Mediated portrayals of student-athletes can provide strong role models for realworld student-athletes. This research explored the images of student-athletes in sportrelated films regarding depictions of drug and alcohol use. A content analysis of six sport-related films released between 1994 and 2000 was conducted 1) to address whether such films accurately depicted drug and alcohol use among student-athletes and 2) to consider how these presentations might impact viewers who are, themselves, high school student-athletes. Results suggested that the films reinforced the notion that student-athletes are supposed to experiment with drugs and alcohol as a part of the social role relative to …

Certified Registered Nurse Anesthetist Performance And Perceptions: Use Of A Handheld, Computerized, Decision Making Aid During Critical Events In A High-Fidelity Human Simulation Environment, Vicki C. Coopmans

Theses and Dissertations

With the increasing focus on patient safety and human error, understanding how practitioners make decisions during critical incidents is important. Despite the move towards evidence-based practice, research shows that much decision making is based on intuition and heuristics (“rules of thumb”). The purpose of this study was to examine and evaluate the methodologic feasibility of a strategy for comparing traditional cognition versus the use of algorithms programmed on a personal digital assistant (FDA) in the management of unanticipated critical events by certified registered nurse anesthetists (CRNAs).

A combined qualitative-quantitative methodology was utilized. The quantitative element consists of a pilot study …

Quality Laboratory Services – Is It Related To Personal Credentials?, Maria Dannessa Delost

Theses and Dissertations

Performance on proficiency test (PT) surveys provides an objective and consistent evaluation of laboratory quality. The goal of the study, a retrospective review of existing PT results (2003) from six clinical laboratories in northeastern Ohio and western Pennsylvania was to determine the relationship of PT performance to the personnel credentials of the laboratory testing personnel. Predictor variables included the practitioner's major area of study, degree, certification and years of laboratory experience.

The study group consisted of 174 testing personnel and 11,689 proficiency-testing results, of which 11,233 were valid and included in the study. Of the 11,233 results, there were 11,120 …

Notes--Experiences At The James Iredell Papers, Donna E. Kelly

Documentary Editing: Journal of the Association for Documentary Editing (1979–2011)

I would like to give you a little background on how I came to be in documentary editing. I've loved history ever since fifth grade. Then in the summer after eighth grade my father and I took a genealogy class. I decided to research my great-great-grandfather, who served as a captain in the Civil War. For the research I went to the State Archives. Once there, I was enamored with it all. On my sixteenth birthday all I wanted to do was to spend the day researching at the Archives in Raleigh. I declared that "I'm gonna work there some …