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2004

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Preparation And Evaluation Of Ocular Inserts Containing Norfloxacin, M. Venkateshwar Rao, Somashekar Shyale Jan 2004

Preparation And Evaluation Of Ocular Inserts Containing Norfloxacin, M. Venkateshwar Rao, Somashekar Shyale

Turkish Journal of Medical Sciences

Norfloxacin is a poorly water soluble drug, and to improve its solubility it was complexed with b-cyclodextrin (BCD). Several ocular patches/inserts of norfloxacin-b-cyclodextrin were prepared in hydroxypropyl methyl cellulose (HPMC) matrix. The influence of rate controlling membranes made of ethyl cellulose (EC) alone and in combination with polyvinyl pyrrolidone K30 (PVP K30) in different proportions on drug release kinetics was studied. The data were subjected to regression analysis. Various physical characteristics of the films were evaluated. In vitro release studies were carried out in a fabricated flow through cell. All the films prepared were found to be uniform in thickness, …


Common Anorectal Conditions, Pravin J. Gupta Jan 2004

Common Anorectal Conditions, Pravin J. Gupta

Turkish Journal of Medical Sciences

No abstract provided.