Digital Commons Network^™

Bioethical Malpractice: Risk And Responsibility In Human Research, Barbara A. Noah

Faculty Scholarship

This Article provides an overview of Institutional Review Board (IRB) operations, reviews the sources of regulatory guidance, and examines the weaknesses of the existing system for the protection of human research subjects. It then discusses the scant case law relating to IRB negligence in the protection of human research subjects and explores some hypothetical circumstances under which it may be appropriate to hold a board accountable for injuries to clinical trial participants. Finally, this Article considers the potential consequences of expanded IRB liability, concluding that tort lawsometimes may serve an important function as a catalyst to regulatory reform when professional …

African American Mothers & Daughters: Socialization, Distance, & Conflict, Kaavonia Hinton

Teaching & Learning Faculty Publications

The black women's literary tradition began in a conscious effort to create a space for black women's writing and to illustrate a distinction between black women's reality and the realities of others (Christian 348–359). The literature within the tradition is influenced by how black women perceive themselves and the world around them. As a result, identity is an important part of African-American women's literature (Hooper 74–81). Race, class, gender, and sexuality are all components of one's identity and are critical in the formation of one's lived experiences (Crenshaw 357–383). Family, from its structure to the function of specific members within …

Description Of A Program For Social Language Intervention: “If You Can Have A Conversation, You Can Have A Relationship, Lee Robinson, Bonnie Brinton, Martin Fujiki

Faculty Publications

Adolescents with impaired language comprehension and formulation skills often experience difficulty keeping up with the linguistic and social demands of peer interaction. This clinical exchange describes an individualized treatment program designed to increase the conversational skill of an adolescent male with language impairment. Treatment focused on increasing awareness of the listener’s needs and on balancing the exchange of conversational turns. Clinical performance, parent report, and client report were used to assess outcomes.

Microstructure Studies In Surfacant Systems, Vivek Agarwal

Open Access Dissertations

Microstructures in two mixed surfactants systems that show novel transformations as a function of composition and temperature have been explored. Indirect imaging methods like Small Angle Neutron Scattering (SANS) along with direct imaging methods like Cryogenic Transmission Electron Microscopy (Cryo-TEM) and recently developed Freeze Fracture Direct Imaging (FFDD have been used extensively to characterize and identify the changes in the microstructures in the mixed surfactant systems as a function of composition, temperature and external force fields.

As water is added to a solution of an anionic surfactant, AOT (2 ethylhexyl sodium sulfosuccinate) and a zwitterionic surfactant, lecithin (phosphatidylcholine) in isooctane, …

Insertion Of Genes And Operons Into The Escherichia Coli Genome Through Targeted Recombination, Dennis Coss

Graduate Theses, Dissertations, and Problem Reports (ETD)

A method whereby DNA sequences of varying size may be accurately inserted into pre-determined locations within the Escherichia coli genome was developed. Using a binary vector system that takes advantage of either the E. coli RecET enzyme tandem or bacteriophage lambda's Redalphabeta recombinatory proteins, this method has the benefits of being both inducible and self-degrading, thereby offering a level of control to the experimenter as well as alleviating any problems that may be associated with leaving residual DNA in the bacterium. To demonstrate the usability of this system, two antibiotic resistance genes, as well as the pyrroloquinoline quinone (pqq) and …

American Fatherhood Types: The Good, The Bad, And The Uninterested, Loren Marks, Rob Palkovitz

Faculty Publications

This paper presents four contemporary types of American manhood: (a) the new, involved father, (b) the good provider, (c) the deadbeat dad, and (d) the paternity-free man. These four types are compared, contrasted, and contextualized with related data from the classic Middletown studies of the 1920s and 1930s. The significance and implications of the trend toward paternity-free manhood are discussed, and directions for future research are suggested.

Thermodynamic Consequences Of Dna Base Modifications And Ligand-Dna Interactions., Rachel Hutchins Graves

All ETDs from UAB

The thermodynamic effects of alterations of the DNA duplex by DNA base modifications or ligand binding are investigated by a combination of spectrophotometric and calorimetric methods. Examination of the effects of substituent modification on the DNA binding energetics of the anticancer agent AAC (Y-[2-(dimethylamino)ethyl]-9-aminoacridine-4-carboxamide) indicated that DNA binding affinities and energetics were enhanced upon substitution at the C5 position on the chromophore of the drug with a variety of chemical groups. A correlation between enthalpies of DNA binding and anticancer activity was evident.The impacts of DNA base modifications, including cytosine arabinoside, deaminated cytosine, and abasic sites, on the thermodynamics of …

Threatened Fishes Of The World: Iotichthys Phlegethontis Cope, 1874 (Cyprinidae), Joseph H. Hanks, Mark C. Belk

Faculty Publications

Common name: least chub.

Predicting Dynamics Of Aggregate Loafing Behavior In Glaucous-Winged Gulls (Larus Glaucescens) At A Washington Colony, Shandelle M. Henson, James L. Hayward, Christina M. Burden, Clara J. Logan, Joseph G. Galusha

Faculty Publications

Seabirds move throughout the day in changing, patchy environments as they engage in various behaviors. We studied the diurnal abundance dynamics of Glaucous-winged Gulls (Larus glaucescens) in a habitat patch dedicated to loafing in the Strait of Juan de Fuca, Washington. We constructed three differential equation models as alternative hypotheses and then used model selection techniques to choose the one that most accurately described the system. We validated the model on an independent data set, made a priori model predictions, and conducted a field test of the predictions. Clear dynamic patterns emerged in the abundance of loafing gulls, even though …

Do Rhinoceros Auklet, Cerorhinca Monocerata, Fledglings Fly To The Sea From Their Natal Burrows?, James L. Hayward, Jere K. Clayburn

Faculty Publications

The mode of departure of Rhinoceros Auklet fledglings from their nest burrows has remained uncertain. Both walk-down and fly-down hypotheses have been proposed. Here we use the unique geography of Protection Island, Washington, to evaluate the fly-down hypothesis. Some fledglings raised on Protection Island do appear to walk to the water, but our results suggest that many of the island's fledgling Rhinoceros Auklets fly to the sea.

Marijuana And Intentions To Use Condoms: Applying The Theory Of Planned Behavior., Albert D. Butts

All ETDs from UAB

No abstract provided.

Variability In The Expression Of Hd Mrna In Mice: Causes And Consequences., Karen T. Dixon

All ETDs from UAB

No abstract provided.

Differential Signaling To Src Family Kinases By Specific Isoforms Of Fibroblast Growth Factor Receptor-1., Jessica Samit Greendorfer

All ETDs from UAB

No abstract provided.

The Effects Of Strong Shocks On Transmembrane Potential, Action Potential Duration, And Intracellular Calcium., Anand N. Iyer

All ETDs from UAB

No abstract provided.

The Roles Of Perlecan In Tumor Growth And Angiogenesis., Xinnong Jiang

All ETDs from UAB

No abstract provided.

Mammalian Cilia In Development And Disease., Patrick D. Taulman

All ETDs from UAB

No abstract provided.

Inhibition Of Hdm2 Oncogene Expression As A Novel Approach To The Treatment Of Glioblastoma Multiforme., Gautam Prasad

All ETDs from UAB

No abstract provided.

The Role Of The Fas System In Bone Turnover., Xiaojun Wu

All ETDs from UAB

No abstract provided.

The Role Of The Transcription Factors Pax5 And E47 In Early Lymphopoiesis., Claudiu Vasile Cotta

All ETDs from UAB

No abstract provided.

Regulating The Vascular Functions Of Nitric Oxide: Novel Roles For The Red Blood Cell In Health And Disease., Jack H. Crawford

All ETDs from UAB

No abstract provided.

Expression And Physiological Significance Of Amiloride-Sensitive Sodium Channels In The Retina., Laura M. Brockway

All ETDs from UAB

No abstract provided.

Modulation Of Endothelial Cell Function By Oxidized Lipids., Erin K. Arnold

All ETDs from UAB

No abstract provided.

Effects Of Transcription On Chromosome Domain Behavior And Characterization Of Transcription-Induced Domain Barriers To Supercoil Diffusion In The Salmonella Typhimurium Chromosome., Shuang Deng

All ETDs from UAB

No abstract provided.

Characterization Of Novel Melanoma-Associated Antigens., Pintusorn Hansakul

All ETDs from UAB

No abstract provided.

Anger And Depression In The Father Relationship., Christopher L. Lucas

All ETDs from UAB

No abstract provided.

Inflammation, Extracellular Matrix Remodeling, And In Vivo Function During Acute And Chronic Cardiac Volume Overload In Rats., Thomas D. Ryan

All ETDs from UAB

No abstract provided.

Mechanism Of Translation Termination In Eukaryotes., Joe Salas-Marco

All ETDs from UAB

No abstract provided.

Middle Infrared Optoelectronic Absorption Systems For Monitoring Physiological Glucose Solutions., W Blake Martin

All ETDs from UAB

No abstract provided.

Perceived Psychosocial Stressors And Social Support Systems Of African American Adolescent Mothers Of At Risk Infants., Shelia Marie Powell Marable

All ETDs from UAB

No abstract provided.

Hyposialylation Of The Ss1 Integrin Subunit Stimulates The Activity Of Myeloid Fibronectin And Vascular Cell Adhesion Molecule-1 Receptors., Alexis Christy Mcbrayer

All ETDs from UAB

No abstract provided.