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Articles 2701 - 2730 of 10405
Full-Text Articles in Entire DC Network
Ideological Criticism Of The Social Construction Of Gay Advertising, Dawn M. Cripe
Ideological Criticism Of The Social Construction Of Gay Advertising, Dawn M. Cripe
Student Work
Mainstream advertising in the gay media has become more prevalent in the past few years as marketers discovered an untapped source of profits. This study examined mainstream advertising in the gay media and its ability to connect with its targeted audience as a diverse consumer group. The study looked through the lens of Berger and Luckmann’s (1966) theory of The Social Construction of Reality and the ideological perspective that gays and lesbians are an oppressed group. The objective of the study was to determine whether or not these advertisements presented a worldview that reinforced stereotypes of gays and lesbians in …
The Magnolia Warbler Dendroica Magnolia On Unaka Mountain, Unicoi County, Tn: Possible Breeding And Habitat Analysis., Kevin Patrick Elam
The Magnolia Warbler Dendroica Magnolia On Unaka Mountain, Unicoi County, Tn: Possible Breeding And Habitat Analysis., Kevin Patrick Elam
Electronic Theses and Dissertations
The chief purpose of this study is to provide information on the habitat and breeding information of Magnolia Warblers on Unaka Mountain. Magnolia Warblers breed in Canada and the Northeastern United States. There are no current breeding records for this species in Tennessee.
For the habitat analysis, trees were identified on individual subplots. Shrubs were analyzed using the point-intercept method. Most of the major tree and shrub species were different than those found in Maine, which is a major breeding region for this species. Therefore, it's the structure of the habitat that is important for nesting. Fledglings were seen, giving …
August 2004 Commencement Program, Bowling Green State University
August 2004 Commencement Program, Bowling Green State University
Commencement Programs
No abstract provided.
The Characterization Of The Expression Of Bog25 And 7a5 In Normal And Cancerous Bladder, Prostate And Breast Cell Lines, Katerine Vanasek
The Characterization Of The Expression Of Bog25 And 7a5 In Normal And Cancerous Bladder, Prostate And Breast Cell Lines, Katerine Vanasek
Theses and Dissertations
The BOG25 family proteins, BOG25 and 7a5, contain domains of the EH- Network family of endocytosis, intracellular sorting and cell fate determination proteins as well as a C-terminal death domain that may play an important role in apoptosis. No other known proteins contain the same domain combinations which makes this family unique. The normal physiological roles of the BOG25 family of proteins are currently unknown, and this is the first study of the possible role of BOG25 and 7a5 in cancer. Additionally, this study is the first to confirm the transcription of mRNA for 7a5, the putative protein identified as …
Cons, Ex-Cons And Odinism Across Cultural And National Borders: Why Attempt To Procure Knowledge And Dare We Not?, Lene T. Vallestad
Cons, Ex-Cons And Odinism Across Cultural And National Borders: Why Attempt To Procure Knowledge And Dare We Not?, Lene T. Vallestad
Theses and Dissertations
The occurrence of right-wing extremism is becoming more prominent in the social landscape of Western European countries, including Norway, and in the United States. Amongst these movements one will find groups that base and justify their racist behavior in religious beliefs. Odinism, a pre-Christian, Norse neopagan faith, has merged racist beliefs and violent behavior with religious creed and ideology, and is a prime example of these right-wing religions.
During the 1990s Odinism emerged as one of the most dynamic trends within the extreme right-wing milieu in the U.S. and Western Europe. The popularity of Odinism today is connected to the …
2004 August, Office Of Communications & Marketing, Morehead State University.
2004 August, Office Of Communications & Marketing, Morehead State University.
Morehead State Press Release Archive, 1961 to the Present
Morehead State University press releases for August of 2004.
A Comparison Of Moth Diversity And Abundance Along An Altitudinal Gradient In Monteverde, Costa Rica, August 2004, Katie Swartz
A Comparison Of Moth Diversity And Abundance Along An Altitudinal Gradient In Monteverde, Costa Rica, August 2004, Katie Swartz
Monteverde Institute: Tropical Ecology and Conservation
Costa Rica has high moth (Lepidoptera) diversity, with relatively little known about its distribution (Hanson 2000). Insects tend to decrease in richness and abundance along an altitudinal gradient (Brehm and Fiedler 2003). Lepidopterans are important indicators of environmental health, important herbivores, vital prey species, and a large draw for the country’s main source of income, ecotourists. The purpose of this study was to compare moth diversity and abundance at varying altitudes. Moths were trapped using an ultra violet light and a sheet at three different altitudes (1530 m, 1639 m, and 1759 m) over six nights between July 26th and …
The San Diego River: A Natural, Historic, And Recreational Resource, John H. Minan
The San Diego River: A Natural, Historic, And Recreational Resource, John H. Minan
San Diego Law Review
The purpose of this Article is to briefly consider the historical importance of the San Diego River, to examine the water quality challenges impacting the River today, and to analyze the principal regulatory programs administered by the Regional Board to meet these challenges. The author's premise is that the water quality of the River is essential to its functional integrity and future.
The Babbler Volume 84 (2004-2005), Lipscomb University
The Babbler Volume 84 (2004-2005), Lipscomb University
The Babbler (Student Newspaper)
The 2004-2005 volume of Lipscomb University's The Babbler student newspaper, which ran from August 2004–April 2005. It had 28 issues, including a special "Freshman Orientation Edition." Issues 13 and 27 were special "Bison Basketball Preview" and "Graduation Edition" issues, respectively. Issues 11 and 20 are misnumbered as 10 and 19 respectively.
Hsp27 Anti-Sense Oligonucleotides Sensitize The Microtubular Cytoskeleton Of Chinese Hamster Ovary Cells Grown At Low Ph To 42 Degrees C-Induced Reorganization, Michael T. Hargis, C. W. Storck, Eric Wickstrom, Leonid A. Yakubov, Dennis B. Leeper, Ronald A. Coss
Hsp27 Anti-Sense Oligonucleotides Sensitize The Microtubular Cytoskeleton Of Chinese Hamster Ovary Cells Grown At Low Ph To 42 Degrees C-Induced Reorganization, Michael T. Hargis, C. W. Storck, Eric Wickstrom, Leonid A. Yakubov, Dennis B. Leeper, Ronald A. Coss
Department of Biochemistry and Molecular Biology Faculty Papers
Chinese hamster ovary (CHO) cells maintained in vitro at pH 6.7 were used to model cells in the acidic environment of tumours. CHO cells grown at pH 6.7 develop thermotolerance during 42 degrees C heating at pH 6.7 and their cytoskeletal systems are resistant to 42 degrees C-induced perinuclear collapse. Hsp27 levels are elevated in cells grown at pH 6.7 and are further induced during 42 degrees C heating, while Hsp70 levels remain low or undetectable, suggesting that Hsp27 is responsible for some of the novel characteristics of these cells. An anti-sense oligonucleotide strategy was used to test the importance …
Use Of 16s Rrna, 23s Rrna, And Gyrb Gene Sequence Analysis To Determine Phylogenetic Relationships Of Bacillus Cereus Group Microorganisms, Sergei G. Bavykin, Yuri P. Lysov, Vladimir Zakhariev, John J. Kelly, Joany Jackman, David A. Stahl, Alexey Cherni
Use Of 16s Rrna, 23s Rrna, And Gyrb Gene Sequence Analysis To Determine Phylogenetic Relationships Of Bacillus Cereus Group Microorganisms, Sergei G. Bavykin, Yuri P. Lysov, Vladimir Zakhariev, John J. Kelly, Joany Jackman, David A. Stahl, Alexey Cherni
Biology: Faculty Publications and Other Works
In order to determine if variations in rRNA sequence could be used for discrimination of the members of the Bacillus cereus group, we analyzed 183 16S rRNA and 74 23S rRNA sequences for all species in the B. cereus group. We also analyzed 30 gyrB sequences for B. cereus group strains with published 16S rRNA sequences. Our findings indicated that the three most common species of the B. cereus group, B. cereus, Bacillus thuringiensis, and Bacillus mycoides, were each heterogeneous in all three gene sequences, while all analyzed strains of Bacillus anthracis were found to be homogeneous. Based on analysis …
Sexually Dimorphic Effects Of Prenatal Stress On Cognition, Hormonal Responses, And Central Neurotransmitters, Rachel E. Bowman, Neil J. Maclusky, Yessenia Sarmiento, Maya Frankfurt, Marisa Gordon, Victoria N. Luine
Sexually Dimorphic Effects Of Prenatal Stress On Cognition, Hormonal Responses, And Central Neurotransmitters, Rachel E. Bowman, Neil J. Maclusky, Yessenia Sarmiento, Maya Frankfurt, Marisa Gordon, Victoria N. Luine
Psychology Faculty Publications
Exposure to stress during gestation results in physiological and behavioral alterations that persist into adulthood. This study examined the effects of prenatal stress on the postnatal expression of sexually differentiated cognitive, hormonal, and neurochemical profiles in male and female rats. Pregnant dams were subjected to restraint stress three times daily for 45 min during d 14-21 of pregnancy. The offspring of control and prenatally stressed dams were tested for anxiety-related and cognitive behaviors, stress and gonadal steroid hormone levels, as well as monoamines and metabolite levels in selected brain regions. Postnatal testosterone levels (measured at 1 and 5 d) did …
Stereotypical Perceptions Of The Communication Behaviors Of Gay Males, Daniel W. Brewster
Stereotypical Perceptions Of The Communication Behaviors Of Gay Males, Daniel W. Brewster
Graduate Theses, Dissertations, and Problem Reports (ETD)
This study examined the stereotypical communication behaviors of gay males. The study examined the associations of assertiveness, responsiveness, homonegativity and biological sex. Participants were 359 (195 men, 164 women) students. Participants provided responses to questions about verbal and nonverbal behaviors for known gay individuals and individuals perceived to be gay. The participants then completed the Assertiveness-Responsiveness Measure (Richmond & McCroskey, 1990) in a self-report and observer-report, and the Modern Homonegativity Scale (Morrison & Morrison, 2002). Results indicated some of the more predominant responses to verbal and nonverbal behaviors are inconsistent with the prevalent societal perceptions of homosexuality. Significant associations between …
Instructor On Demand: Can Online Delivery Of Lectures Promote Learning Achievement?, Rebecca Ann Martindale
Instructor On Demand: Can Online Delivery Of Lectures Promote Learning Achievement?, Rebecca Ann Martindale
Graduate Theses and Dissertations
Reported enrollments of students taking online courses in institutes of higher learning in the 2000-01 academic years were estimated at 3.077 million, according to the U.S. Department of Education’s National Center for Educational Statistics (NCES). Dramatic enrollment increases have led to a need for research that involves both the comparison of learning achievement based on delivery mediums, and student attitudes concerning alternative delivery methods. This study compared the learning achievement of students when the deliveries of course lectures were presented both in-class and online, as well as measured attitudes of students concerning delivery mediums. Both types of lectures were presented …
Influence Of A Three-Week Wildlife Education Curriculum On Knowledge And Attitudes Of South Carolina's Marlboro County High School Ninth And Tenth-Grade Biology Students, Diane M. Krishon
Graduate Theses, Dissertations, and Problem Reports (ETD)
The purpose of this study was to assess the influence of a three-week wildlife education curriculum on knowledge and attitudes of ninth and tenth-grade biology students in South Carolina. A three-week wildlife curriculum was incorporated into three high school biology classes in the same semester. The students were pre-tested and post-tested for knowledge and attitudes. The results indicate that the three-week curriculum had a positive influence on knowledge but did not influence wildlife attitudes. However, a substantial correlation occurred between the post-test attitude and knowledge scores, indicating that as students' knowledge increased, their attitudes towards wildlife and environmental education became …
Demography And Genetic Structure Of An Allegheny Woodrat Population In Northcentral West Virginia, Mary Elizabeth Manjerovic
Demography And Genetic Structure Of An Allegheny Woodrat Population In Northcentral West Virginia, Mary Elizabeth Manjerovic
Graduate Theses, Dissertations, and Problem Reports (ETD)
The Allegheny woodrat (Neotoma magister) occurs throughout the Appalachian Mountains forming isolated colonies in rock outcrops, cliffs, and caves. In the past 20--30 years, populations along the northern and western peripheries of the range have experienced drastic declines. There have been suggested reasons for this decline but a lack of long-term data has prevented application of specific management actions. In recent years, there has been more insight into population structure, gene flow, and relatedness among colonies. The objectives of my study were to examine these factors at a localized level to further assist with future management decisions.;Using data collected over …
Nutrient Remobilization During Development And Senescence Of Petunia X Hybrida Floral Organs, Karyn L. Smith
Nutrient Remobilization During Development And Senescence Of Petunia X Hybrida Floral Organs, Karyn L. Smith
Graduate Theses, Dissertations, and Problem Reports (ETD)
Fresh weight, dry weight, and macronutrient content of corollas, ovaries, and styles were measured during the development and senescence of several wild-type and transgenic Petunia x hybrida plants. Flowers of age-related senescence exhibited growth, maintenance, and senescence phases during development. Flowers terminated by pollination-induced senescence exhibited only growth and senescence phases. Fresh and dry weight of Mitchell, V26, and SAG12-IPT corollas followed patterns previously observed in climacteric flowers. SAG12-IPT, a cytokinin overproducing plant, exhibited a prolonged maintenance phase compared to V26. A temporary increase in fresh weight, dry weight, and macronutrients of Mitchell corollas occurred at the expected onset of …
Axial Ligand Binding Equilibria As Probes Of The Effective Steric Bulk Of Substituted Tetraarylporphyrins, Michael Craig Thomas
Axial Ligand Binding Equilibria As Probes Of The Effective Steric Bulk Of Substituted Tetraarylporphyrins, Michael Craig Thomas
Graduate Theses, Dissertations, and Problem Reports (ETD)
Equilibrium constants and thermodynamic data are reported for coordination of various axial ligands to the zinc(II) complexes of tetra( p-tolyl)porphyrin, tetra(3,5-bis(biphenylmethoxy)phenyl)porphyrin, tetra(2,6-(perfluorobenzoxy)phenyl)porphyrin, and tetra(2,6-di(methoxy)phenyl)porphyrin in toluene at 25.0°C. With respect to coordination of a planar ligand to a zinc(II) porphyrin, the equilibrium constant varied with the identity of the meso-substituent in the order 3,5-bis-(biphenylmethoxy)phenyl > p-tolyl > 2,6-(perfluorobenzoxy)phenyl >> 2,6-di-(methoxy)phenyl. With respect to coordination of a non-planar ligand to a zinc(II) porphyrin, the order was 3,5-bis(biphenylmethoxy)phenyl > p-tolyl >> 2,6-(perfluorobenzoxy)phenyl ≈ 2,6-di(methoxy)phenyl. Thermodynamic data for the coordination of 3- and 4-phenylpyridine to zinc tetra(2,6-di(methoxy)phenyl) porphyrin show a greater loss of entropy than for the coordination …
Synchronization Of Spatiotemporal Patterns And Modeling Disease Spreading Using Excitable Media, Jianxia Cui
Synchronization Of Spatiotemporal Patterns And Modeling Disease Spreading Using Excitable Media, Jianxia Cui
Graduate Theses, Dissertations, and Problem Reports (ETD)
Studies of the photosensitive Belousov-Zhabotinsky (BZ) reaction are reviewed and the essential features of excitable media are described. The synchronization of two distributed Belousov-Zhabotinsky systems is experimentally and theoretically investigated. Symmetric local coupling of the systems is made possible with the use of a video camera-projector scheme. The spatial disorder of the coupled systems, with random initial configurations of spirals, gradually decreases until a final state is attained, which corresponds to a synchronized state with a single spiral in each system. The experimental observations are compared with numerical simulations of two identical Oregonator models with symmetric local coupling, and a …
Mechanism Of Action Of Nsc3852, A Breast Cancer Differentiation Agent, Anna Martirosyan
Mechanism Of Action Of Nsc3852, A Breast Cancer Differentiation Agent, Anna Martirosyan
Graduate Theses, Dissertations, and Problem Reports (ETD)
The development of tumor cell differentiation agents is new initiative in cancer treatment research. The goal of this project was to identify breast cancer differentiation agents by screening quinoline ring-containing compounds obtained form National Cancer Institute Compound Library. Of six differentiation-inducing quinolines NSC3852 was chosen as a "lead" compound. Our results demonstrate that NSC3852 is an inhibitor of HDAC activity in HeLa and MCF-7 cells nuclear extracts. NSC3852 caused superoxide generation in MCF-7 cells in a NADPH oxidase-dependent fashion, and NSC3852-induced oxidative stress led to the shift in a redox potential of the cells to a more oxidized state. This …
Estimating Net Photosynthesis And Productivity Of A Loblolly Pine Forest Grown With Carbon Dioxide Enrichment, Clint J. Springer
Estimating Net Photosynthesis And Productivity Of A Loblolly Pine Forest Grown With Carbon Dioxide Enrichment, Clint J. Springer
Graduate Theses, Dissertations, and Problem Reports (ETD)
I examined the long-term effects of elevated CO2 on the leaf chemistry and photosynthesis of four species growing in the understory and two species growing in the overstory at the Duke Forest FACE experiment. I then used these measurements to parameterize a process based forest productivity model, PnET-II, in order to model the net primary productivity of the portions of the forest growing under ambient and elevated CO2. Finally, I performed a greenhouse study that examined the effects of elevated CO 2 and water availability on the growth and biomass allocation of loblolly pine seedlings from four distinct geographic locations. …
Rna Analysis As A Method To Determine The Age Of A Biological Sample, Stacey E. Anderson
Rna Analysis As A Method To Determine The Age Of A Biological Sample, Stacey E. Anderson
Graduate Theses, Dissertations, and Problem Reports (ETD)
DNA analysis by Polymerase Chain Reaction (PCR) allows for the unambiguous identification of the person from whom a biological sample was derived but provides no information about when the sample was deposited. The ability to determine the age of blood or a biological sample would be of significant benefit to the forensic science community. This would provide a temporal linkage between the blood of the perpetuator and the commission of a crime or it could be used to exclude evidence that does not correspond to the time a crime was committed. It was hypothesized that ex vivo RNA decay was …
Effects Of Artificial Neural Network Speed-Based Inputs On Heavy-Duty Vehicle Emissions Prediction, Nastaran Hashemi
Effects Of Artificial Neural Network Speed-Based Inputs On Heavy-Duty Vehicle Emissions Prediction, Nastaran Hashemi
Graduate Theses, Dissertations, and Problem Reports (ETD)
The PM split study was performed in Southern California on thirty-four heavy-duty diesel vehicles using the West Virginia University Transportable Heavy-Duty Vehicle Emissions Testing Laboratories to gather emissions data of these vehicles. The data obtained from six vehicles in the 1985--2001 model year and 33,000--80,000 lb weight range exercised through three different cycles were selected in this thesis. To predict the instantaneous levels of oxides of nitrogen (NOx), carbon dioxide (CO2), hydrocarbons (HC) and carbon monoxide (CO), an Artificial Neural Network (ANN) was used. Axle speed, torque, their rates of change over different time periods and two other variables as …
Smoking And Dose-Dependent Early Effects Of Nicotine On Bone Mechanical Properties And Histology, Daniel Shaw Porter
Smoking And Dose-Dependent Early Effects Of Nicotine On Bone Mechanical Properties And Histology, Daniel Shaw Porter
Graduate Theses, Dissertations, and Problem Reports (ETD)
The objective was to study the effects of nicotine and cigarette smoke on mechanical properties of cortical bone. Experiments were conducted for 5 weeks with New Zealand White Rabbits. The first experiment of 18 rabbits studied the effect of nicotine levels delivered via a nicotine patch (5.25, 10.5, 21 ng/ml), measured by different mechanical tests, porosity, and composition. There was no significant difference between the control and the treatment groups.;The second experiment of 22 rabbits studied the effects of nicotine delivered via a nicotine patch (10.5 ng/ml) and via a smoking chamber on fracture toughness and porosity. The rabbits exposed …
Developing The Portability Indices And The Portable Code Generator, Gregory E. Mundy
Developing The Portability Indices And The Portable Code Generator, Gregory E. Mundy
Graduate Theses, Dissertations, and Problem Reports (ETD)
Portability is recognized as a highly desirable characteristic of contemporary software design. However, research in the area has not been forthcoming in recent years and much of the work related to the field is ad hoc and speculative at best.;This study attempted to establish a framework for deriving a probabilistic measure of software portability that may be useful in aiding developers to make key design decisions that will result in some quantifiable level of portability while minimizing the cost of incorporating portable design into the software production process.;The research also explored the potential portability benefits that may be derived from …
Translation, Adaptation And Validation Of An Instrument To Evaluate Hiv/Aids Knowledge And Attitudes For Use With Salvadorian High School Students, Carlos Salvador Zometa Iii
Translation, Adaptation And Validation Of An Instrument To Evaluate Hiv/Aids Knowledge And Attitudes For Use With Salvadorian High School Students, Carlos Salvador Zometa Iii
USF Tampa Graduate Theses and Dissertations
This study translated, cross-culturally adapted and validated an instrument's scores for use in public high schools in San Salvador, El Salvador. The original instrument consisted of items developed by the Centers for Disease Control and Prevention (CDC) to assess HIV/AIDS knowledge and five dimensions of attitudes (Abstinence, Peer-pressure, Condom use, Drug use, and Threat of HIV) in grades 7 to 12 in the United States. Items were translated into Spanish using the back-translation method. The instrument was cross-culturally adapted using guidelines proposed by Guillemin, Bombardier, and Beaton (1993). A cross-culturally equivalent version of the original instrument was obtained using three …
It's A Small World After All: Making The Case For The Extraterritorial Application Of The National Environmental Policy Act, Browne C. Lewis
It's A Small World After All: Making The Case For The Extraterritorial Application Of The National Environmental Policy Act, Browne C. Lewis
Cardozo Law Review
No abstract provided.
Spectroscopic And X-Ray Crystallographic Characterization Of Bestatin Bound To The Aminopeptidase From Aeromonas (Vibrio) Proteolytica, Carin C. Stamper, David L. Bienvenue, Brian Bennett, Dagmar Ringe, Gregory A. Petsko, Richard C. Holz
Spectroscopic And X-Ray Crystallographic Characterization Of Bestatin Bound To The Aminopeptidase From Aeromonas (Vibrio) Proteolytica, Carin C. Stamper, David L. Bienvenue, Brian Bennett, Dagmar Ringe, Gregory A. Petsko, Richard C. Holz
Physics Faculty Research and Publications
Binding of the competitive, slow-binding inhibitor bestatin ([(2S,3R)-3-amino-2-hydroxy-4-phenylbutanoy]-leucine) to the aminopeptidase from Aeromonas proteolytica (AAP) was examined by both spectroscopic and crystallographic methods. Electronic absorption spectra of the catalytically competent [Co_(AAP)], [CoCo(AAP)], and [ZnCo(AAP)] enzymes recorded in the presence of bestatin revealed that both of the divalent metal ions in AAP are involved in binding bestatin. The electron paramagnetic resonance (EPR) spectrum of the [CoCo(AAP)]−bestatin complex exhibited no observable perpendicular- or parallel-mode signal. These data indicate that the two CoII ions in AAP are antiferromagnetically coupled yielding an S = 0 ground state and suggest …
Diet, Physical Activity, And Television Viewing In Relation To The Body Weight Status Of West Virginia Adolescents, Kimberly M. Morris
Diet, Physical Activity, And Television Viewing In Relation To The Body Weight Status Of West Virginia Adolescents, Kimberly M. Morris
Graduate Theses, Dissertations, and Problem Reports (ETD)
Context. The obesity epidemic is now threatening youth. Yet little is known regarding the factors associated with adolescent weight status.;Objective. To determine whether dietary intakes, physical activity, and hours spent viewing television are related to the body weight status of West Virginia adolescents.;Design, setting, and participants. This descriptive study included survey, diet recall, and body mass index data from 1,036, 14--20 year olds attending West Virginia high schools during the years 2002 to 2003.;Results. Overweight students consumed less kilocalories (∼378) (P < .001), less servings of total grains (P < .01) and a greater percentage of their energy from protein (P = .01). A significantly less amount of overweight students reported participating in strengthening/toning physical activities on three or more days of the week (P < .01).;Conclusion. Overweight adolescents within the state of West Virginia appear more likely to restrict their energy intake rather than exercise to lose weight. Thus, public health intervention strategies to help these students reach a healthy weight while maintaining adequate nutrition are imperative.
Ctp Synthase And Transporter Function In Coxiella Burnetii, Jeffrey D. Miller
Ctp Synthase And Transporter Function In Coxiella Burnetii, Jeffrey D. Miller
Graduate Theses, Dissertations, and Problem Reports (ETD)
Coxiella burnetii is a gram negative, obligate intracellular parasite that can only replicate in the acidified environment of a phagosome. Like other intracellular parasites, C. burnetii depends on the host cell for many of the substrates required for growth, such as amino acids. It had been observed that avirulent C. burnetii Nine Mile strain (Phase II) organisms in BHK-21 fibroblasts displayed improved growth when extracellular cytidine was introduced to infected cultures. This improved growth was not observed in wild type organisms in the same cell system. This observation, coupled with early enzyme activity studies, suggested that Phase II organisms had …