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January 12, 2004 Reporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.

Volume 41, Number 18: January 09, 2004, University Of North Dakota

University Letter Archive

No abstract provided.

The Inkwell, Armstrong Atlantic State University

The Inkwell

No abstract provided.

Decreased Shedding Of Escherichia Coli O157:H7 By Cattle Following Vaccination With Type Iii Secreted Proteins, Andrew A. Potter, Sandra Klashinsky, Yuling Li, Elizabeth Frey, Hugh Townsend, Dragan Rogan, Galen E. Erickson, Susanne Hinkley, Terry J. Klopfenstein, Rodney A. Moxley, David R. Smith, B. Brett Finlay

School of Veterinary and Biomedical Sciences: Faculty Publications

Cattle are an important reservoir of Escherichia coli O157:H7 leading to contamination of food and water, and subsequent human disease. This pathogen colonizes its hosts by producing several proteins such as Tir and EspA that are secreted by a type III secretion system. These proteins play a role in colonization of the intestine, suggesting that they might be useful targets for the development of a vaccine to reduce levels of this organism in cattle. Vaccination of cattle with proteins secreted by E. coli O157:H7 significantly reduced the numbers of bacteria shed in feces, the numbers of animals that shed, and …

Quantum: Research, Scholarship & Creative Works At The University Of New Mexico, 2004, Office Of The Vice President For Research

Office of the Vice President for Research

No abstract provided.

Cvm Annual Report 2004, College Of Veterinary Medicine, University Of The Philippines Los Baños

CVM Reports

No abstract provided.

The Equation, Winter 2004, College Of Science And Mathematics, Wright State University

College of Science and Mathematics Newsletters

This 6 page newsletter discusses various happenings within the College of Science and Mathematics. It begins with a letter from the dean, and continues on with news, events, alumni news, and other community news.

Estimating The True Prevalence Of Mycobacterium Bovis In Hunter-Harvested White-Tailed Deer In Michigan, Daniel J. O’Brien, Stephen M. Schmitt, Dale E. Berry, Scott D. Fitzgerald, Jolene R. Vanneste, Timothy J. Lyon, Diane Magsig, Jean S. Fierke, Thomas M. Cooley, Laura S. Zwick, Bruce V. Thomsen

Michigan Bovine Tuberculosis Bibliography and Database

Apparent prevalence, although useful as a consistent index, may underestimate the true prevalence of disease. In Michigan, the ability to estimate the true prevalence of bovine tuberculosis (TB; caused by Mycobacterium bovis) in free-ranging white-tailed deer (Odocoileus virginianus) will become increasingly important to accurately assess progress towards eradication. Our objectives were threefold: to estimate the true prevalence of M. bovis in free-ranging deer in Michigan, to evaluate the effectiveness of existing TB surveillance methods, and to indirectly assess whether TB epidemiologic data from captive cervid herds can be meaningfully extrapolated to free-ranging populations. The study population consisted …

Synapsis: Philadelphia Campus (2004), Philadelphia College Of Osteopathic Medicine

All Yearbooks

This yearbook includes AIDS Walk, Bridging the Gaps, West Philadelphia Health Fair, Heart Walk, Blood Drives, Halloween, Follies, Football, DO Day on the Hill, Parties, Spring Formal, Prom, Clubs, A Capella, American College Of Osteopathic Family Practitioners, ACOFP, American Holistic Medical Association, AHMA, Asian Medical and Health Association, AMHA, American Medical Student Association, AMSA, American Medical Women's Association, AMWA, American Medical Association, AMA, Biomedical Sciences, Business in Medicine, Christian Medical Association, Cycling, Emergency Medicine, Internal Medicine, Jewish Physician's Network, Kappa Sigma Phi, KSPh, (ΚΣΦ), Lesbian Gay Bisexual Transgender People in Medicine and Allies, Martial Arts, Men's Rugby, Obstetrics & Gynecology, …

Download Full Pdf Issue-Jefferson Translations, Vol. 2, No. 1, Fall/Winter 2004-2005

Jefferson Translations

This issue includes an article on Jefferson's Heart Failure center, a highlight on Dr. Eckhart of Translational Medicine, faculty news and awards, a report on strong outcomes for liver transport team, the latest in asthma research and a master's program in human investigation.

Progress Notes, Lehigh Valley Health Network

Progress Notes

No abstract provided.

Hepp Report: Infectious Diseases In Corrections, Vol. 7 No. 1, Hiv & Hepatitis Education Prison Project

Infectious Diseases in Corrections Report (IDCR)

No abstract provided.

In Vivo Targeting Of Antigens To Maturing Dendritic Cells Via The Dec-205 Receptor Improves T Cell Vaccination, Laura C. Bonifaz, David P. Bonnyay, Anna Charalambous

Publications

The prevention and treatment of prevalent infectious diseases and tumors should benefit from improvements in the induction of antigen-specific T cell immunity. To assess the potential of antigen targeting to dendritic cells to improve immunity, we incorporated ovalbumin protein into a monoclonal antibody to the DEC-205 receptor, an endocytic receptor that is abundant on these cells in lymphoid tissues. Simultaneously, we injected agonistic α-CD40 antibody to mature the dendritic cells. We found that a single low dose of antibody-conjugated ovalbumin initiated immunity from the naive CD4⁺ and CD8⁺ T cell repertoire. Unexpectedly, the αDEC-205 antigen conjugates, given s.c., …

Antimicrobial And Spermicidal Activity Of Hydrogen Peroxide And Nonoxynol-9 Based Gel Preparations, Paul E. Grimmett

Theses, Dissertations and Capstones

Eighty gel formulations were prepared using five buffer systems (0.01M citrate, 0.02M citrate, 0.01M tartrate, 0.02M tartrate, and 0.01M citrate/0.01M tartrate), four hydrogen peroxide (H2O2) concentrations (0%, 0.3%, 0.9%, and 1.2%), and four nonoxynol-9 (N-9) concentrations (0%, 1%, 1.5%, and 2%). The eighty gel formulations were then tested for physio-chemical properties (viscosity and pH), antimicrobial effectiveness (Minimum Inhibitory Concentration Assay) against Candida albicans, Escherichia coli, and Streptococcus agalactiae, and finally, spermicidal effectiveness (Sander Cramer Assay). The gel formulation that contained the best combination of physio-chemical, antimicrobial, and spermicidal properties was a 0.01M citrate buffered hydrogel, which contained 0.9% H2O2 and …

Severe Acute Respiratory Syndrome : Description, Epidemiology, And Control Measures, Jorge E. Galva

International Journal of Global Health and Health Disparities

Severe Acute Respiratory Syndrome (hereinafter SARS) is the first severe and readily transmissible new disease to emerge in the 21st century 1. The presence of this infectious agent was first recognized in early November 2002 in the province of Guangdong in the People's Republic of China. SARS rapidly spread from there to other parts of the world, notably Southeast Asia and Canada. According to data compiled in August 2003, altogether 8,422 cases occurred in 29 countries. The most severely affected countries were China (including the Special Administrative Region of Hong Kong and Taiwan), Canada, Singapore and Vietnam, all of which …

Epidemiologic And Environmental Investigation Of A Recreational Water Outbreak Caused By Two Genotypes Of Cryptosporidium Parvum In Ohio In 2000, Els Mathieu, Deborah A. Levy, Fran Veverka, Mary-Kay Parrish, John Sarisky, Nancy Shapiro, Stephanie Johnston, Thomas Handzel, Allen Hightower, Lihua Xiao, Yeuk-Mui Lee, Steve York, Michael Arrowood, Robin Lee, Jeffrey L. Jones

Journal Articles: Epidemiology

In August 2000, the Ohio Department of Health requested assistance to investigate a cryptosporidiosis outbreak with more than 700 clinical case-patients. An epidemiologic and environmental investigation was conducted. Stool specimens, pool water, and sand filter samples were analyzed. A community-based case-control study showed that the main risk factor was swimming in pool A (odds ratio [OR] = 42, 95% confidence interval [CI] = 12.3-144.9). This was supported by results of polymerase chain reaction (PCR) analysis, which showed the presence of both the human and bovine genotypes of Cryptosporidium parvum in case-patients and samples from the filter of pool A. A …

Did A Severe Flood In The Midwest Cause An Increase In The Incidence Of Gastrointestinal Symptoms?, Timothy J. Wade, Sukhminder K. Sandhu, Deborah A. Levy, Sherline Lee, Mark W. Lechevallier, Louis Katz, John M. Colford

Journal Articles: Epidemiology

Severe flooding occurred in the midwestern United States in 2001. Since November 2000, coincidentally, data on gastrointestinal symptoms had been collected for a drinking water intervention study in a community along the Mississippi River that was affected by the flood. After the flood had subsided, the authors asked these subjects (n = 1,110) about their contact with floodwater. The objectives of this investigation were to determine whether rates of gastrointestinal illness were elevated during the flood and whether contact with floodwater was associated with increased risk of gastrointestinal illness. An increase in the incidence of gastrointestinal symptoms during the flood …

Geographic Dynamics Of Viral Encephalitis In Thailand, Timothy Jensen Henrich

Yale Medicine Thesis Digital Library

No abstract provided.

Molecular Typing Of Mycobacterial Isolates Cultured From The Tissue Of Inflammatory Bowel Disease (Crohn's Disease) Patients, Leanne M. Adams

Electronic Theses and Dissertations

The role of Mycobacterium avium subsp paratuberculosis (MAP) in the etiology and pathogenesis of inflammatory bowel disease (IBD) including Crohn's Disease (CD), has been investigated. The fastidious characteristics and cross reactivity of MAP with other members in Mycobacteria have produced significant challenges in their detection and identification. In this two year pilot study, an array of three PCR molecular assays based on the detection of sequences from the16S rRNA, IS1245, and IS900 genes, belonging to members of the MAC, have been developed and optimized into a common protocol to be used as a rapid and accurate diagnostic tool regarding M. …

Analysis Of Common Tick Species Collected From The Chattanooga-Hamilton Region Of Tennessee And The Correlation To Reported Cases Of Tick-Borne Diseases, Astrid Von-Walter

Capstone Research Projects

Amblyomma americanum, Dermacentor variabilis, Ixodes scapularis, and Rhipicephalus sanguineus are three-host ticks commonly found in the Chattanooga-Hamilton region of Tennessee. The first three species are medically important because they are known to transmit Ehrlichiosis, Rocky Mountain spotted fever, and Lyme disease, respectively. Rhipicephalus is not known to vector any pathogens infecting humans; therefore, not clinically significant. The focus of this study was to correlate the population of A. americanum, D. variabilis, and I. scapularis in the Chattanooga region to reported cases of tick -borne diseases. There was a direct relationship between the frequency of D. variabilis and the reported cases …

College Of Osteopathic Medicine Program Overview, Nova Southeastern University

Health Professions Divisions Course Catalogs and Course Descriptions

No abstract provided.

Fourth Annual Symposium In Virology, John Owens

John Owens: Speeches and Appearances

What a pleasure it is to take part in welcoming you to this Fourth Annual Symposium in Virology. Such a tremendous program lies ahead! And how pleased and proud we are that this year's symposium is a special tribute to our colleague Dr. James Van Etten, Professor of Plant Pathology in our Institute of Agriculture and Natural Resources here at the University of Nebraska-Lincoln, who last-year was elected to membership in the National Academy of Sciences.

Dihydrofolate Reductase Mutations In Plasmodium Vivax From Indonesia And Therapeutic Response To Sulfadoxine Plus Pyrimethamine, Michele D. Hastings, Kathryn M. Porter, Jason D. Maguire, Ika Susanti, Winni Kania, Michael J. Bangs, Carol Hopkins Sibley, J. Kevin Baird

United States Navy: Publications

Background. The target enzyme of pyrimethamine is dihydrofolate reductase (DHFR), but little is known about allelic variants of dhfr in Plasmodium vivax populations. Still less is known about associations between specific alleles and the failure of sulfadoxine/pyrimethamine (S/P) to clear the erythrocytic stages of P. vivax in vivo.

Methods. We studied P. vivax dhfr mutations in 24 patients who received S/P therapy in Papua or Central Java, Indonesia, and we measured the resistance of the alleles in vitro in a dhfr yeast expression assay.

Results. Fourteen (58%) of 24 patients had an inadequate therapeutic response. Two of 6 alleles that …

Hepatocellular Carcinoma In The Woodchuck Model Of Hepatitis B Virus Infection, Bud C. Tennant, Ilia A. Toshkov, Simon F. Peek, James R. Jacob, Stephan Menne, William E. Hornbuckle, Raymond D. Schinazi, Brent E. Korba, Paul J. Cote, John L. Gerin

United States Department of Veterans Affairs: Publications

The Eastern woodchuck (Marmota monax) harbors a DNA virus (Woodchuck hepatitis virus [WHV]) that is similar in structure and replicative life cycle to the human hepatitis B virus (HBV). Like HBV, WHV infects the liver and can cause acute and chronic hepatitis. Furthermore, chronic WHV infection in woodchucks usually leads to development of hepatocellular carcinoma (HCC) within the first 2–4 years of life. The woodchuck model has been important in the preclinical evaluation of safety and efficacy of the antiviral drugs now in use for treatment of HBV infection and continues to serve as an important, predictive model …

Program Booklet, Allen K. Lanham, Christine Derrickson, Peggy Manley

Elizabeth I: Program Booklet

The program booklet for the "Elizabeth I: Ruler and Legend" exhibit at Booth Library.

The Impact Of Hiv-Associated Neuropsychological Impairment On Everyday Functioning, Robert K. Heaton, Thomas D. Marcotte, Monica Rivera-Mindt, Joseph Sadek, David J. Moore, Heather Bentley, J Allen Mccutchan, Carla Reicks, Igor Grant, The Hnrc Group

Psychology Faculty Publications

HIV-1 infection can be associated with neuropsychological (NP) deficits ranging from subtle to severe. The purpose of this study was to evaluate the functional, or “real-world” impact of HIV-associated NP impairment in a group of 267 HIV-infected participants. All participants received comprehensive NP, neuromedical, and standardized functional evaluations that included laboratory measures of shopping, cooking, financial management, medication management and vocational abilities. Compared to NP-normal participants, those with NP impairment performed significantly worse on all laboratory measures of everyday functioning. Multivariate analyses revealed that the NP ability domains of Abstraction/Executive Function, Learning, Attention/Working Memory and Verbal abilities most strongly and …

Fighting Medicare Fraud In Long-Term Care Hospitals-Within-Hospitals: Oig Documents Ongoing Failures While Industry Groups Complain, Susan E. Cancelosi

Law Faculty Research Publications

No abstract provided.

Apoptosis And Porcine Reproductive And Respiratory Syndrome Virus, Laura C. Miller, James M. Fox

Roman L. Hruska U.S. Meat Animal Research Center: Reports

Despite numerous studies examining the possible induction of apoptosis in porcine reproductive and respiratory syndrome virus (PRRSV)-infected cells, it remains unclear if PRRSV infection results in direct apoptotic induction. There is clear evidence that apoptotic cells are present in tissues from PRRSV-infected pigs. However, many of these studies have failed to show that the apoptotic cells are infected with PRRSV. This has led some investigators to propose that ‘‘bystander’’ cells, not infected cells, become apoptotic during PRRSV infection by a yet undetermined mechanism. Studies examining the induction of the apoptotic gene expression response to PRRSV infection are needed to determine …

Beta-2-Microglobulin Haplotypes In U.S. Beef Cattle And Association With Failure Of Passive Transfer In Newborn Calves, Michael L. Clawson, Michael P. Heaton, Carol G. Chitko-Mckown, James M. Fox, Timothy P. L. Smith, Warren M. Snelling, John W. Keele, William W. Laegreid

Roman L. Hruska U.S. Meat Animal Research Center: Reports

Failure of passive transfer (FPT) is a condition in which neonates do not acquire protective serum levels of maternal antibodies. A principal component of antibody transport is the neonatal receptor for the Fc portion of immunoglobulin, a heterodimer of a MHC-1 alpha-chain homolog (FCGRT) and beta- 2-microglobulin (B2M). Previously, two FCGRT haplotypes were associated with differences in immunoglobulin G (IgG) passive transfer in cattle (Laegreid et al. (2002) Mamm Genome 13, 704–710). The present study had two objectives: first, to characterize the B2M haplotype structure in a diverse group of U.S. beef cattle, and second, to evaluate those haplotypes for …

Research At Nebraska, 2003-2004 Report, University Of Nebraska-Lincoln

Office of Research and Economic Development: Publications

This publication is a snapshot of the fiscal year’s activities. To read more stories about research and creativity at Nebraska, visit the online edition at http://research.unl.edu/news/04-ORG-005_AR_Final.pdf. Additional multimedia are available for many stories.