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Population Pharmacokinetics Of Cyclosporine In Heart And Lung Transplant Patients, Gautam Baheti

Open Access Master's Theses

Pharmacokinetics involves the analysis of plasma concentration and time data to obtain models that summarize the absorption, distribution and elimination parameters of a drug. The population approach to pharmacokinetics involves the estimation of mean pharmacokinetic parameters and their variability within the population.

Cyclosporine is a widely used immunosuppressive agent, and its pharmacokinetic parameters are characterized by a large variation in blood concentrations after oral or intravenous administration. Cyclosporine being a narrow therapeutic index drug is associated with significant consequences if the drug is present in 'sub-therapeutic' or 'supra-therapeutic' concentration. Optimization of therapy is challenging owing to variable pharmacokinetic parameters and …

An Analysis Of A Spatial Relationship Between Homeownership And Crime: A Case Of The North End Of Providence, Rhode Island, Masatoshi Nakahata

Open Access Master's Theses

This research project examines the spatial relationship between homeownership and crime. The first chapter states the Problem Statement, Objective and Significance of the study, and Organization of the study.

The second chapter discusses previous literature related to the study. The four related fields of the literature discussed are, 1) urban neighborhood and crime, 2) built-social environment of urban neighborhood and crime, 3) homeownership and built social environment of urban neighborhood, and 4) homeownership and crime in urban neighborhoods.

The third chapter inventories the existing conditions of the North End. It begins with the historical context of the North End. Then, …

Downtown Attleboro, Massachusetts Urban Design Study, Scott Mcpartlin

Open Access Master's Theses

No abstract provided.

A Redevelopment Plan For The Monastery In Cumberland, Rhode Island, Craig S. Pereira

Open Access Master's Theses

This research project proposes a plan for the redevelopment of the Monastery in Cumberland, Rhode Island. The study will detail the history and cultural value of the site to the people of Cumberland, Rhode Island. The environmental setting will be defined and evaluated to determine environmental constraints to development through Geographic Information System (GIS) mapping and a site survey of existing conditions. The site will also be evaluated through the perspective of land use regulations, political issues, and trends in programs for the preservation/ protection of open space.

A major consideration in the development of this plan was the Town …

An Analysis Of Development Impact Fees Prepared For The City Of Warwick, Jonathan J. Reiner

Open Access Master's Theses

This research project was written to for the City of Warwick using methodology found in: A Practitioner's Guide to Development Impact Fees by James C. Nicholas, Arthur C. Nelson, and Julian C. Juergensmeyer; Development Impact Fees Edited by Arthur C. Nelson, The Calculation of Proportionate-Share Impact Fees by James C. Nicholas, Development Impact published by the Urban Land Institute, the North Kingstown and South Kingston Development Impact Fee Reports and many other local and national sources as identified in the bibliography. This report is in conformance with the Rhode Island Development Fee Act (RI General Laws Chapter 45 §22.4).

This …

Prototypes: The Modern Retail Industry In Suburban Communities, Benjamin Paul Hartley

Open Access Master's Theses

The implementation of the "prototype", large or small, has become the de facto strategy for national and regional corporations to compete in today's retail market. The prototype, in terms of retail development, refers to the creation of a single building and site design that is to be applied, with the smallest amount of variation possible, each time a new store is constructed. Almost universally, the building is square and utilitarian, the entrance faces the street, large parking areas are located between the entrance and street and perhaps to the side, and a loading area is placed in the back. The …

Town Of Hopkinton 2003 Affordable Housing Plan: An Analysis Of Affordable Housing Needs And A Plan For Creating Affordable Housing, Adopted By The Hopkinton Town Council 11/03, Jason King

Open Access Master's Theses

This plan was commissioned by the Planning Department of the Town of Hopkinton, Rhode Island in 2004. Its purpose was to study the affordable housing situation in Hopkinton and make recommendations that would increase the quantity of affordable housing in the town through the introduction of new regulatory and planning policies.

If followed the plan would lead to the creation of: 1) a Mandatory lnclusionary Zoning Ordinance, 2) an Affordable Housing Foundation, 3) an Affordable Housing Trust Fund, 4) a policy of using local discretionary funds for affordable housing programs, 5) a commitment to contract a private non-profit housing organization …

Annual Report Uta Library For The Combined Years Of 2002-2003 And 2003-2004, University Of Texas At Arlington Library

UTA Libraries Staff Publications - Archive

The purpose of the UTA Library Annual Report is to document and communicate the significant accomplishments, initiatives, and contributions of The University of Texas at Arlington Library and their staff. The Annual Report also recognizes the important contributions of the Libraries' donors.

88th Annual Meeting, 2004. Secretary's Report And Financial Statement, Academy Editors

Journal of the Arkansas Academy of Science

No abstract provided.

Tailwater Recovery Systems For Irrigation: Benefit/Cost Analysis And Water Resource Conservation Technique In Northeast Arkansas, Jennifer L. Bouldin, Nate A. Bickford, H. B. Stroud, G. S. Guha

Journal of the Arkansas Academy of Science

Water, one of the earth's most vital resources, is particularly significant in the Arkansas Delta agricultural landscape. While both surface and groundwater are extremely important, 94% of the 26.9 billion L (7.1 billion gal) of water pumped daily from the Alluvial Aquifer is used for agricultural purposes. This common property is subsequently being depleted and sustainable conservation methods are being pursued. State and federal incentive programs encourage the use of a tailwater recovery system in agricultural irrigation. With the use of a complete recovery system, benefits include not only government incentives for wetland habitat, but reduced groundwater use and decreased …

Additions To The Aquatic Diptera (Chaoboridae, Chironomidae, Tabanidae, Tipulidae) Fauna Of The White River National Wildlife Refuge, Arkansas, Stephen W. Chordas Iii, Patrick L. Hudson, Eric G. Chapman

Journal of the Arkansas Academy of Science

The dipteran fauna of Arkansas is generally poorly known. A previous study of the Aquatic macroinvertebrates of the White River National Wildlife Refuge, the largest refuge in Arkansas, reported only 12 diptera taxa out of 219 taxa collected (Chordas et al., 1996). Most of the dipterans from this study were identified only to the family level. The family Chironomidae is a large, diverse group and was predicted to be much more diverse in the refuge than indicated by previous studies. In this study, Chironomidae were targeted, with other aquatic or semiaquatic dipterans also retained, in collections designed to better define …

Journal Of The Arkansas Academy Of Science - Volume 58 2004, Academy Editors

Journal of the Arkansas Academy of Science

No abstract provided.

Impact Of Black Shale Weathering On Sediment Quality, G. M. Ogendi, R. E. Hannigan, Jerry L. Farris, D. Smith

Journal of the Arkansas Academy of Science

Weathering of black shales leads to elevated metal concentrations in both surface water and stream sediments. In spite of the recent focus on black shales, few data exist on the ecological impacts of this process particularly on aquatic organisms. The key objective of this study was to determine the impact of trace metal concentrations in sediments upon aquatic organisms. To achieve the above objective, stream sediment samples were collected from streams draining black shale and limestone (used as a reference stream) lithologies located in central Arkansas between June 2003 and January 2004. Trace metal concentrations were measured by the dynamic …

Human Rabies Post-Exposure Treatment In Arkansas, 1994-2000, D. Blake Sasse

Journal of the Arkansas Academy of Science

The Arkansas Department of Health recorded 118 incidents where humans in Arkansas were treated following exposure to confirmed rabid animals from 1994-2000. Domestic species accounted for 64% of incidents and 76% of total human exposures with the ratio of human exposures per rabid animal 17 times higher for domestic animals than wild animals. Records of 218 cases of human exposure to potentially rabid wild animals during this period were also examined to determine method of contact. While 72% of cases involving raccoons (Procyon lotor), skunks (Mephitis mephitis and Spilogale putorius), and foxes (Urocyon cinereoargenteus and Vulpes vulpes) were initiated by …

Parasites (Coccidia, Trematoda, Nematoda) From Selected Bats Of Arkansas, Chris T. Mcallister, Steve J. Upton, Charles R. Bursey

Journal of the Arkansas Academy of Science

No abstract provided.

Not Separate But Still Unequal: Disparities, Invisibility And Bias In Access And Quality Of Health Care In Michigan, Kelly Kammeraad

McNair Scholars Journal

Current research points to race and ethnicity as predictive of disparities in access and quality of health care. A 2002 Institute of Medicine Study found that African-American patients tend not to receive the same type of care as White patients, even when controlling for socioeconomic status. Self-reported perceptions of racial bias within the patient provider relationship, from the patient’s perspective, are analyzed to uncover the subtle ways perceptions of differential treatment based on racial bias work to create barriers or perpetuate disparities in health outcomes for African-American breast cancer survivors in Michigan.

Gender And Empowerment: Contemporary Lakota Women Of Rosebud, Christina G. Mello

McNair Scholars Journal

Western-European stereotypes still permeate Plains Indian culture suggesting that women were passive and subjugated while men were dominant warriors. This research challenges those stereotypes through exploration of origin and spirituality accounts, kinship organization, historical impact, contemporary and traditional issues, and through first hand ethnographic research of the Sicangu Nation of Lakota people in regards to gender roles. Using feminist critique and reflexive theoretical approaches, information was collected through participant observation and interviews with Sicangu people in 2004. By focusing on how Lakota women have empowered themselves, this research illustrates how women were and continue to be respected, influential members of …

Investigating The Relationship Between Parenting Styles And Delinquent Behavior, Danielle J. Terry

McNair Scholars Journal

Although numerous studies have examined the connection between delinquent behavior and parenting styles in children and adolescents, limited research has been done to determine if there is an ongoing relationship between these variables in the college population. This study included 38 college students and examined the relationship between parenting styles; families studied were authoritative, authoritarian, indulgent, and uninvolved. It was predicted that authoritarian parenting practices would be highly correlated with delinquent behavior, particularly for students with a difficult temperament and low family cohesion.

Psychopaths In The Courtroom: A Preliminary Report On Judicial Sentencing For Violent Offenses, John Traxler

McNair Scholars Journal

Every day, judges are faced with making decisions about a defendant’s potential risk as it relates to setting bail, sentencing, and a variety of other contexts. In making these decisions, judges must balance issues of fairness and protection of the individual rights of the accused with protection of society from dangerous predators who may commit future acts of physical or sexual violence. As professionals who are not specifically trained in violence assessment, judges must rely on others, including probation agents, attorneys, and expert witnesses, for information to assist in their decision-making. Through expert witnesses and up-to-date training of criminal justice …

Pulmonary Infiltrates During Chemotherapy-Induced Febrile Neutropenia: Incidence, Patterns And Outcomes, N. Gangat, M.A.A. Khan, M. Mujib, Mohammad Khurshid

Section of Haematology/Oncology

OBJECTIVE: To analyze the incidence, etiologies, radiographic patterns, and clinical outcomes of adult leukemics with prolonged febrile neutropenia and pneumonia.
METHODS: A retrospective study was conducted at a tertiary care hospital. The medical records of adult patients with acute myeloid leukemia diagnosed between January 1989 and June 2000 and undergoing induction chemotherapy were included. Only the patients who presented with a pulmonary infiltrate, secondary leukemia (e.g., transformed chronic myeloid leukemia underlying myelodysplastic syndrome, or disease following alkylating agent therapy) were included and those developing infiltrates following consolidation chemotherapy were excluded.
RESULTS: A total of 124 patients were admitted …

Sleep Hygiene And Sleep Quality In Italian And American Adolescents, Monique K. Lebourgeois, Flavia Giannotti, Flavia Cortesi, Amy Wolfson, John R. Harsh

Faculty Publications

This study investigated cross-cultural differences in adolescent sleep hygiene and sleep quality. Participants were 1348 students (655 males; 693 females) aged 12-17 years from public school systems in Rome, Italy (n = 776) and Southern Mississippi (n = 572). Participants completed the Adolescent Sleep-Wake Scale and the Adolescent Sleep Hygiene Scale. Reported sleep hygiene and sleep quality were significantly better for Italian than American adolescents. A moderate linear relationship was observed between sleep hygiene and sleep quality in both samples (Italians: R =.40; Americans: R =.46). Separate hierarchical multiple regression analyses showed that sleep hygiene accounted for significant variance in …

Division By Blood: Examining A History Of Political And Racial Clashes Underlying American Indian Identity, Barbara Anne Henderson

Graduate Student Theses, Dissertations, & Professional Papers

No abstract provided.

The Knight Volume 14: Issue 8, Nova Southeastern University

Student Newspapers

No abstract provided.

The Death Penalty--An Obstacle To The "War Against Terrorism"?, Thomas M. Mcdonnell

Vanderbilt Journal of Transnational Law

September 11 seared our collective memory perhaps even more vividly than December 7, 1941, and has evoked a natural demand both for retribution and for measures to keep us safe. Given the existing statutory and judicial authority for capital punishment, the U.S. Government has to confront the issue whether to seek the death penalty against those who are linked to the suicide attacks or to the organization that sponsored them or both. Meting out the death penalty to international terrorists involves difficult moral, legal, and policy questions. The September 11 crimes were not only domestic crimes, but also international ones. …

Enhancing The Legitimacy Of The World Trade Organization, Andrea Greisberger

Vanderbilt Journal of Transnational Law

The World Trade Organization (WTO) has faced harsh criticism from developing nations in recent years. Many developing nations feel that the promises they received when they joined the WTO have not been fulfilled. These nations feel that wealthy, industrialized nations like the United States and the members of the European Union are the only ones that have benefited from the organization. Moreover, they feel that these developed nations have benefited at their expense through the WTO's dispute settlement process. Many improvements to the WTO have been proposed. However, the one that seems the most able to help developing nations, the …

Return To Europe? The Czech Republic And The Eu's Influence On Its Treatment Of Roma, Matthew D. Marden

Vanderbilt Journal of Transnational Law

The Czech Republic has faced much criticism in the past fifteen years for the treatment of its Romani minority community. The European Union has successfully applied informal, non-legal means of pressuring the Czech Republic into making some changes necessary to improve living conditions for Roma. With the Czech Republic's recent accession to the European Union, legal human rights institutions will likely play a larger role in ensuring that the Czech Republic continues to improve conditions for Czech Roma. The Author uses a case brought by a group of Roma at the European Court of Human Rights to demonstrate the potential …

The Lives Of Animals, The Lives Of Prisoners, And The Revelations Of Abu Ghraib, Charles H. Brower, Ii

Vanderbilt Journal of Transnational Law

In this Article, Professor Brower suggests that the images depicting inhuman treatment of detainees at the Abu Ghraib prison contain timely lessons about the function and the importance of legal personality. To illustrate this thesis, the Author first identifies animals as a population condemned to an existence bereft of the protections that accompany legal personality. Next, the Author describes the chilling similarities between the treatment of animals and the treatment of prisoners in Iraq and in the so-called "Global War on Terror." Finally, the Author discusses three potential lessons for a nation widely perceived to have retreated from its commitment …

Lipid-Lowering Effects Of Ethyl 2-Phenacyl-3-Aryl-1h-Pyrrole- 4-Carboxylates In Rodents, Justin M. Holub, Kathy O'Toole-Colin, Adam Getzel, Anthony Argenti, Michael A. Evans, Daniel C. Smith, Gerard A. Dalglish, Shahzad Rifat, Donna L. Wilson, Brett M, Taylor, Ulander Miott, Josephine Glersaye, Kam Suet Lam, Bryan J. Mccranor, Joshua D. Berkowitz, Robert B. Miller, John R. Lukens, Keith Krumpe, John T. Gupton, Bruce S. Burnham

Chemistry Faculty Publications

A series of substituted 2-phenacyl-3-phenyl-1H-pyrrole-4-carboxylates were prepared from substituted acetophenones in 6 steps. The final condensations between a chloroenal and an aminoketone were carried out under neutral conditions in parallel to yield the series listed below. Selected pyrrole derivatives proved to be potent hypolipidemic agents lowering serum triglyceride concentrations in CF-1 male mice after 14 days of I.P. administration. One agent orally lowered serum cholesterol in Sprague-Dawley male rats at 2mg/kg/day after 14 days. The agents demonstrated a lowering of mouse serum LDL- cholesterol levels and selected compounds showed an elevation of serum HDL-cholesterol levels. The cholesterol concentrations in the …

Physiological And Psychological Mediators Of Ethnic Group Differences In Laboratory Pain Sensitivity., Leanne Renee Cianfrini

All ETDs from UAB

No abstract provided.

Molecular Epidemiology And Characterization Of Macrolide And Fluoroquinolone Resistance In Streptococcus Pneumoniae., Crystal N. Johnson

All ETDs from UAB

No abstract provided.