Digital Commons Network^™

Electroporation And Electrophoresis System And Method For Achieving Molecular Penetration Into Cells In Vivo, Richard Heller, Richard Gilbert, Mark J. Jaroszeski, Loree C. Heller, Melinda L. Lucas

USF Patents

The electroporation system and method combine pulses having different characteristics for delivering molecules to cells in vivo. The pulses include a high-intensity pulse for inducing electroporation and a low-intensity pulse to induce electrophoretic molecule movement within an interstitial space, molecule adherence to a cell membrane, and electrophoretic movement of the molecule through the permeabilized membrane. The use of a high-intensity and a low-intensity pulse achieves improved delivery; reduction of intensity and/or duration of pulses for inducing electroporation; and decreased muscle stimulation, tissue damage, and patient discomfort.

Treatment Of Breast Cancer, Delbert Miles, Elena Goun, Elena Goun, Krasnych Pertrovna, Krasnych Pertrovna, Pimenova Valentinovna, Solodnikov Yurjevich, Solodnikov Yyrjevitsh

UCF Patents

Compounds of the class of 4-oxo-butenoic acid derivatives are disclosed along with the surprising use property of these compounds as a anti-tumor agents in humans against breast carcinoma, which include: 2-(N'-Fluoren-9-ylidene-hydrazino)-5,5-dimethyl-4-oxo-hex-2-enoic acid methyl ester (OF-06), 1-(2,4-Dimethyl-phenyl)-2,4-dihydroxy-3-4-methyl-benzoyl)-5-oxo-2,5-dihydro-1H-pyrrole-2-carboxylic acid methyl ester (1F-07), 4-(4-Methoxy-phenyl)-2,4-dioxo-3-(phenyl-hydrazono)-butyric acid (3F-10), 4-(4-Chloro-phenyl)-2,4-dioxo-3-(phenyl-hydrazono)-butyric acid ethyl ester (3F-11), 2-Hydroxy-4-oxo-4-(2,3,5,6-tetrafluoro-4-methoxy-phenyl)-but-2-enoic acid (3F-15), and 4,4-Dihydroxy-5-4-methyl-benzoyl)-2-phenyl-2,4-dihydro-pyrazol-3-one (3F-16) as well as some novel derivatives of these compounds claimed (see Table 2). The invention also encompasses a class of the compounds with the novel property of anti-tumor activity against human breast cancer, which includes the following compounds 4-(4-Ethoxy-phenyl)-2-(N'-fluoren-9-ylidene-hydrazino)-2-hydroxy-4-oxo-butyric acid methyl ester (OF-13); 2-{N'-[1-(4-Chloro-phenyl)-ethylidene]-hydrazino}-4-oxo-4-phenyl-but-2-enoic acid methyl …

The Bg News March 30, 2004, Bowling Green State University

BG News (Student Newspaper)

The BGSU campus student newspaper. March 30, 2004. Volume 94-Issue 123.

Executive Committee - Agenda, 3/30/2004, Academic Senate

Academic Senate Agendas

No abstract provided.

Multimedia And Interactive Components In Converged Media, Amanda L. Welch

USF Tampa Graduate Theses and Dissertations

A content analysis of news Web sites reveals how many multimedia and interactive components both converged and non-converged media organizations include on their Web presence. The sample included four news Web sites considered to be highly converged with their print and broadcast counterparts (TBO.com, chicagotribune.com, DallasNews.com, and Azcentral.com), one newspaper Web site not affiliated with a broadcast media organization (buffalonews.com), and one broadcast news Web site not affiliated with a print news organization (kfmb.com). A multimedia and interactivity score was given to each Web site based on the quantity of these components each site used. Both kfmb.com (a non-converged organization) …

Arbiter, March 29, Students Of Boise State University

Student Newspapers

No abstract provided.

Covering Up 30 Years Of Radioactive And Hazardous Waste: Mixed Waste Landfill From U.S. Department Of Energy/Sandia National Laboratories, Citizen Action (Through New Mexico Community Foundation), Sue Dayton

Citizen Action (through New Mexico Community Foundation)

Comments submitted to the NMED regarding the Class 3 Permit Modification/Corrective Measures Study for the Mixed Waste Landfill.

This research was completed money allocated during Round 4 of the Citizens’ Monitoring and Technical Assessment Fund (MTA Fund). Clark University was named conservator of these works.

If you have any questions or concerns please contact us at [email protected]

The Statesman, V. 47, I. 45, State University Of New York At Stony Brook

Stony Brook Statesman-Sucolian

v. 47, i. 45

The Probe, Issue 232 – March/April 2004

The Probe: Newsletter of the National Animal Damage Control Association

• NADCA President, Art Smith, arranged a meeting of NADCA members who were attending the 21st Vertebrate Pest Conference in Visalia, CA on March 2, 2004.
• The California Nuisance Wildlife Control Operators Association (CNWCOA) has joined Urban Wildlife Management, Inc. and its President, Alan Merrifield in a civil rights lawsuit against the State of California.
• Proceedings Available FROM THE WILDLIFE DAMAGE MANAGEMENT WORKING GROUP, THE WILDLIFE SOCIETY: 10th WILDLIFE DAMAGE MANAGEMENT CONFERENCE, K. A. Fagerstone & G. W. Witmer, Editors; THE 9th WILDLIFE DAMAGE MANAGEMENT CONFERENCE, M. C. Brittingham, J. Kays, and R. McPeake, Editors
• NADCA Addresses …

Dermatology For The Practicing Allergist: Tinea Pedis And Its Complications, Muhannad Al Hasan, S. Matthew Fitzgerald, Mahnaz Saoudian, Guha Krishnaswamy

ETSU Faculty Works

Tinea pedis is a chronic fungal infection of the feet, very often observed in patients who are immuno-suppressed or have diabetes mellitus. The practicing allergist may be called upon to treat this disease for various reasons. Sometimes tinea infection may be mistaken for atopic dermatitis or allergic eczema. In other patients, tinea pedis may complicate allergy and asthma and may contribute to refractory atopic disease. Patients with recurrent cellulitis may be referred to the allergist/immunologist for an immune evaluation and discovered to have tinea pedis as a predisposing factor. From a molecular standpoint, superficial fungal infections may induce a type2 …

March 29, 2004 Reporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.

Hawks' Herald - March 29, 2004, Roger Williams University

Hawk's Herald

No abstract provided.

Feminist Author And Activist To Speak At Unh, Erika Mantz

Media Relations

No abstract provided.

The Bg News March 29, 2004, Bowling Green State University

BG News (Student Newspaper)

The BGSU campus student newspaper. March 29, 2004. Volume 94-Issue 122.

Coyote Depredation Management: Current Methods And Research Needs, Brian R. Mitchell, Michael M. Jaeger, Reginald H. Barrett

United States Department of Agriculture Wildlife Services: Staff Publications

This paper examines the severity of livestock depredation by coyotes (Canis latrans), reviews evidence implicating breeding (or “alpha”) coyotes in the majority of incidents, evaluates currently used depredation control techniques, and suggests directions for future research. Nonlethal control ranges from varied animal husbandry practices to coyote behavioral modification or sterilization. These methods show significant promise but have not been proven effective in controlled experiments. Therefore, many livestock producers rely on lethal control, and most employ nonselective strategies aimed at local population reduction. Sometimes this approach is effective; other times it is not. This strategy can fail because the …

Central Florida Future, Vol. 36 No. 53, March 29, 2004

Central Florida Future

Activities board sets its sights on Chappelle - if it can afford him; Plants face last stand: Arboretum Greenhouse could fall this week; Watergate symposium brings famous reporter; Campus club rallies for gay marriage.

Ammonia Flux At The Air/Water Interface Of Tampa Bay, Constance Anne Mizak

USF Tampa Graduate Theses and Dissertations

An ammonia emissions inventory discovered that 90% of the ammonia emitted from Pinellas, Hillsborough, and Polk counties, originated from the latter two counties. This finding is significant and suggests that a substantial portion of the ammonia deposited to Tampa Bay is transported with easterly air masses.

Ammonia and ammonium concentrations at the coastal Gandy Bridge site were seasonally and diurnally consistent, but the rural Sydney site showed greater variability. It was determined that wind direction was the most influential parameter affecting the Gandy Bridge site, which supports the hypothesis that an advection of ammonia from the east is a major …

Mostly Music: Mar. 28, 2004, Mostly Music Staff

Mostly Music

Carl Ratner, Matthew Agnew, Jane Kenas-Heller

Efficacy Of Aircraft Landing Lights In Stimulating Avoidance Behavior In Birds, Bradley F. Blackwell, Glen E. Burnhardt

United States Department of Agriculture Wildlife Services: Staff Publications

Aircraft collisions with wildlife (primarily birds) are costly in terms of injury or loss of human life, loss of the animals involved, damage to property and business, and the use of lethal control of wildlife at airports worldwide. One potential nonlethal technique to reduce bird–aircraft collisions—pulsed white and wavelength-specific aircraft-mounted light—has been considered for nearly 3 decades, but the efficacy of the technique has not been evaluated quantitatively. We tested the hypothesis that during daylight, captive birds exposed to an approaching ground-based vehicle exhibiting pulsing 250-W white aircraft landing lights would initiate avoidance behavior more quickly than birds experiencing an …

Washington University Record, March 26, 2004

Washington University Record

No abstract provided.

The Tiger Vol. 97 Issue 20 2004-03-26, Clemson University

Tiger Newspapers

No abstract provided.

The Bison, March 26, 2004

The Bison Newspapers

No abstract provided.

Volume 41, Number 29: March 26, 2004, University Of North Dakota

University Letter Archive

No abstract provided.

The Bg News March 26, 2004, Bowling Green State University

BG News (Student Newspaper)

The BGSU campus student newspaper. March 26, 2004. Volume 94-Issue 121.

Crusader, March, 26, 2004, College Of The Holy Cross

Student Newspapers

The student newspaper for the College of the Holy Cross in Worcester, Massachusetts. Articles include coverage of campus events and issues, sports, editorials and special features.

Proximate Cues For Ovarian Recrudescence And Ovulation In The Brown Treesnake (Boiga Irregularis) Under Laboratory Conditions, Tom Mathies, Elizabeth A. Franklin, Lowell A. Miller

United States Department of Agriculture Wildlife Services: Staff Publications

The reproductive biology of the brown treesnake (Boiga irregularis), an invasive tropical species known primarily for the extensive ecological damage it has caused on the island of Guam (Savidge 1987), is poorly understood. This is not for lack of sampling effort by researchers-it is simply because reproduction apparently occurs in all months of the year (Rodda et al. 1999) and periodic sampling in such systems cannot detect the phenology of major reproductive events (e.g., ovarian recrudescence, ovulation, oviposition) and other important life history attributes (e.g., frequency of reproduction). In such systems, repeated observations of individuals may be the …

Judicial Recognition Of The Interests Of Animals - A New Tort, David Favre

ExpressO

This article seeks to explore a simple but profound question. How should our legal system deal with the claims of animals for protection against harms inflicted by humans? Rather than a comparative rights analysis as used by some writers, this article will use the non-comparative approach based upon an interest analysis. The short answer is that our legal system can and should do what it always has done, balance the interests of competing individuals in a public policy context, always seeking to strike an ethically appropriate balance. It will be shown that the legislative branch of our government presently promotes …

March 2004 - Advisory Council Meeting

ALEC Committee Minutes

No abstract provided.

The Four Hundred And Twenty-First Report Of The Curricular Affairs Committee Resubmitted With Statement On Transfer Of 100 Level Writing Courses, University Of Rhode Island Faculty Senate

Faculty Senate Bills

No abstract provided.

Rotunda - Vol 83, No 21 - March 25, 2004, Longwood University

Rotunda

No abstract provided.