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Thurston Cable Construction And/Or Freemont Comp. V. Labor Commission Of Utah And Kirk S. Demille : Reply Brief, Utah Court Of Appeals

Utah Court of Appeals Briefs (1996–2006)

REPLY BRIEF OF APPELLANTS Appeal from the Utah Labor Commission.

David Beazer V. Jenee Hatton Farnsworth, State Of Utah And Office Of Recovery Services : Brief Of Appellee, Utah Court Of Appeals

Utah Court of Appeals Briefs (1996–2006)

BRIEF OF APPELLEE

APPEAL FROM THE DECREE OF DIVORCE THIRD JUDICIAL DISTRICT COURT, SALT LAKE COUNTY STATE OF UTAH, JUDGE JOSEPH C. FRATTO

The Boundaries Of Human Rights Jurisdiction In Europe, Dinah Shelton

Duke Journal of Comparative & International Law

No abstract provided.

Estimation Of Cumulative Incidence Functions In Competing Risks Studies Under An Order Restriction, Hammou El Barmi, Subhash C. Kochar, Hari Mukerjee, Francisco J. Samaniego

Mathematics and Statistics Faculty Publications and Presentations

In the competing risks problem an important role is played by the cumulative incidence function (CIF), whose value at time t is the probability of failure by time t for a particular type of failure in the presence of other risks. Its estimation and asymptotic distribution theory have been studied by many. In some cases there are reasons to believe that the CIFs due to two types of failure are order restricted. Several procedures have appeared in the literature for testing for such orders. In this paper we initiate the study of estimation of two CIFs subject to a type …

State Of Utah V. Ivan Larsen : Brief Of Appellant, Utah Court Of Appeals

Utah Court of Appeals Briefs (1996–2006)

No abstract provided.

Angiotensin Ii Enhances Adenylyl Cyclase Signaling Via Ca2+/Calmodulin. Gq-Gs Cross-Talk Regulates Collagen Production In Cardiac Fibroblasts, Rennolds S. Ostrom, Jennifer E. Naugle, Miki Hase, Caroline Gregorian, James S. Swaney, Paul A. Insel, Laurence L. Brunton, J. Gary Meszaros

Pharmacy Faculty Articles and Research

Cardiac fibroblasts regulate formation of extracellular matrix in the heart, playing key roles in cardiac remodeling and hypertrophy. In this study, we sought to characterize cross-talk between Gq and Gs signaling pathways and its impact on modulating collagen synthesis by cardiac fibroblasts. Angiotensin II (ANG II) activates cell proliferation and collagen synthesis but also potentiates cyclic AMP (cAMP) production stimulated by β-adrenergic receptors (β-AR). The potentiation of β-AR-stimulated cAMP production by ANG II is reduced by phospholipase C inhibition and enhanced by overexpression of Gq. Ionomycin and thapsigargin increased intracellular Ca2+ levels and potentiated isoproterenol- and forskolin-stimulated cAMP production, whereas …

University Of Central Florida Ir 3-Year Fact Book - Ay 2000-2001 Through Ay 2002-2003, University Of Central Florida

Historical Fact Book and Enrollment

Historical fact book and enrollment data for the University of Central Florida.

Lim Kinase 1 Is Essential For The Invasive Growth Of Prostate Epithelial Cells - Implications In Prostate Cancer, Monica Davila, Andra R. Frost, William E. Grizzle, Ratna Chakrabarti

Faculty Bibliography 2000s

Mammalian LIM kinase 1 (LIMK1) is involved in reorganization of actin cytoskeleton through inactivating phosphorylation of the ADF family protein cofilin, which depolymerizes actin filaments. Maintenance of the actin dynamics in an ordered fashion is essential for stabilization of cell shape or promotion of cell motility depending on the cell type. These are the two key phenomena that may become altered during acquisition of the metastatic phenotype by cancer cells. Here we show that LIMK1 is overexpressed in prostate tumors and in prostate cancer cell lines, that the concentration of phosphorylated cofilin is higher in metastatic prostate cancer cells, and …

Sulfolipid Deficiency Does Not Affect The Virulence Of Mycobacterium Tuberculosis H37rv In Mice And Guinea Pigs, Cécile Rousseau, Oliver C. Turner, Erik Rush, Yann Bordat, Tatiana D. Sirakova, Pappachan E. Kolattukudy, Shannon Ritter, Ian M. Orme, Brigitte Gicquel, Mary Jackson

Faculty Bibliography 2000s

Lipids that are found only in the cell envelope of pathogenic mycobacteria, such as those containing multiple methyl-branched fatty acids, have long been thought to play a role in pathogenesis. Among these complex lipids, sulfolipids have been the most extensively studied over the last 50 years. The numerous biological effects exhibited by purified sulfolipids on phagocytic cells led to the idea that these molecules are probably important virulence factors facilitating the intracellular survival of Mycobacterium tuberculosis. However, definitive evidence to support this concept has been lacking. The recent construction of an isogenic sulfolipid-deficient mutant of M. tuberculosis H37Rv (Sirakova et …

Coherence Properties Near Interfaces Of Random Media, A. Apostol, A. Dogariu

Faculty Bibliography 2000s

The spatial coherence theory of optical fields radiated by statistically homogeneous, infinite, planar sources does not account for detailed surface characteristics. However, coherence properties change with the angular distribution of the intensity radiated from such a source, which, in turn, depends on the physical properties of the sample. We show that second-order correlations of the optical field measured at several wavelengths away from the surface of a highly inhomogeneous medium relate to the statistical characteristics of the interface.

The Role Of Geometric Constraints In Amphiphilic Self-Assembly: A Brownian Dynamics Study, Geuorgui K. Bourov, Aniket Bhattacharya

Faculty Bibliography 2000s

We use a stochastic molecular dynamics simulation method to investigate the effect of optimal head group area in amphiphilic self-assembly. For a fixed tail geometry, we choose several sizes of the effective head group area and carry out a detailed study of how this affects the critical micelle concentration (CMC), the cluster distribution, and the shape of micelles for different concentrations and temperature. We find that with an increase of the effective head group area, the CMC is attained at a larger concentration of the free chains at all temperatures. Likewise, for a given concentration, amphiphiles with the larger effective …

Use Of Population Viability Analysis And Reserve Selection Algorithms In Regional Conservation Plans, Carlos Carroll, Reed F. Noss, Paul C. Paquet, Nathan H. Schumaker

Faculty Bibliography 2000s

Current reserve selection algorithms have difficulty evaluating connectivity and other factors necessary to conserve wide-ranging species in developing landscapes. Conversely, population viability analyses may incorporate detailed demographic data, but often lack sufficient spatial detail or are limited to too few taxa to be relevant to regional conservation plans. We developed a regional conservation plan for mammalian carnivores in the Rocky Mountain region using both a reserve selection algorithm (SITES) and, a spatially explicit population model (PATCH). The spatially explicit population model informed reserve selection and network design by producing data on the locations of population sources, the degree of threat …

Characterization Of A Novel And Specific Inhibitor For The Pro-Apoptotic Protease Omi/Htra2, Lucia Cilenti, Younghee Lee, Sibylle Hess, Srinivasa Srinivasula, Kwon Moo Parrk, Daniela Junqueira, Hedvika Davis, Joseph V. Bonventre, Emad S. Alnemri, Antonis S. Zervos

Faculty Bibliography 2000s

Omi/HtrA2 is a mammalian serine protease with high homology to bacterial HtrA chaperones. Omi/HtrA2 is localized in mitochondria and is released to the cytoplasm in response to apoptotic stimuli. Omi/HtrA2 induces cell death in a caspase-dependent manner by interacting with the inhibitor of apoptosis protein as well as in a caspase-independent manner that relies on its protease activity. We describe the identification and characterization of a novel compound as a specific inhibitor of the proteolytic activity of Omi/HtrA2. This compound (ucf-101) was isolated in a high throughput screening of a combinatorial library using bacterially made Omi-(134-458) protease and fluorescein-casein as …

Biochemical Function Of Msl5 (Pks8 Plus Pks17) In Mycobacterium Tuberculosis H37rv: Biosynthesis Of Monomethyl Branched Unsaturated Fatty Acids, Vinod S. Dubey, Tatiana D. Sirakova, Michael H. Cynamon, Pappachan E. Kolattukudy

Faculty Bibliography 2000s

We show that the disruption of one of the mycocerosic acid synthase (mas)-like genes, msl5 (pks8 plus pks17) in Mycobacterium tuberculosis H37Rv generates a mutant incapable of producing monomethyl branched unsaturated C-16 to C-20 fatty acids that are minor constituents of acyltrehaloses and sulfolipids. The msl5 mutation did not cause any significant change in the acyl lipid composition and also did not affect growth in culture, in mouse alveolar macrophage cell line MH-S, or in the murine lung.

Potential Involvement Of Extracellular Signal-Regulated Kinase 1 And 2 In Encystation Of A Primitive Eukaryote, Giardia Lamblia - Stage-Specific Activation And Intracellular Localization, John G. Ellis Iv, Monica Davila, Ratna Chakrabarti

Faculty Bibliography 2000s

Mitogen-activated protein kinase (MAPK) pathways are major signaling systems by which eukaryotic cells convert environmental cues to intracellular events such as proliferation and differentiation. We have identified Giardia lamblia homologues of two members of the MAPK family ERK1 and ERK2. Functional characterization of giardial ERK1 and ERK2 revealed that both kinases were expressed in trophozoites and encysting cells as 44- and 41-kDa polypeptides, respectively, and were catalytically active. Analysis of the kinetic parameters of the recombinant proteins showed that ERK2 is similar to5 times more efficient than ERK1 in phosphorylating myelin basic protein as a substrate, although the phosphorylating efficiency …

A General Paradigm To Model Reaction-Based Biogeochemical Processes In Batch Systems, Yilin Fang, Gour-Tsyh Yeh, William D. Burgos

Faculty Bibliography 2000s

[1] This paper presents the development and illustration of a numerical model of reaction-based geochemical and biochemical processes with mixed equilibrium and kinetic reactions. The objective is to provide a general paradigm for modeling reactive chemicals in batch systems, with expectations that it is applicable to reactive chemical transport problems. The unique aspects of the paradigm are to simultaneously (1) facilitate the segregation (isolation) of linearly independent kinetic reactions and thus enable the formulation and parameterization of individual rates one reaction by one reaction when linearly dependent kinetic reactions are absent, (2) enable the inclusion of virtually any type of …

A Chloroplast Transgenic Approach To Hyper-Express And Purify Human Serum Albumin, A Protein Highly Susceptible To Proteolytic Degradation, Alicia Fernández-San Millán, Angel Mingo-Castel, Michael Miller, Henry Daniell

Faculty Bibliography 2000s

Human Serum Albumin (HSA) accounts for 60% of the total protein in blood serum and it is the most widely used intravenous protein in a number of human therapies. HSA, however, is currently extracted only from blood because of a lack of commercially feasible recombinant expression systems. HSA is highly susceptible to proteolytic degradation in recombinant systems and is expensive to purify Expression of HSA in transgenic chloroplasts using Shine-Dalgarno sequence (SD), which usually facilitates hyper-expression of transgenes, resulted only in 0.02% HSA in total protein (tp). Modification of HSA regulatory sequences using chloroplast untranslated regions (UTRs) resulted in hyper-expression …

Discrete Vector Solitons In Two-Dimensional Nonlinear Waveguide Arrays: Solutions, Stability, And Dynamics, J. Hudock, P. G. Kevrekidis, B. A. Malomed, Demetrios N. Christodoulides

Faculty Bibliography 2000s

We identify and investigate bimodal (vector) solitons in models of square-lattice arrays of nonlinear optical waveguides. These vector self-localized states are, in fact, self-induced channels in a nonlinear photonic-crystal matrix. Such two-dimensional discrete vector solitons are possible in waveguide arrays in which each element carries two light beams that are either orthogonally polarized or have different carrier wavelengths. Estimates of the physical parameters necessary to support such soliton solutions in waveguide arrays are given. Using Newton relaxation methods, we obtain stationary vector-soliton solutions, and examine their stability through the computation of linearized eigenvalues for small perturbations. Our results may also …

Body Image Among Older, Rural, African-American Women With Type 2 Diabetes, Leslie Sue Lieberman, Claudia K. Probart, Nancy E. Schoenberg

Faculty Bibliography 2000s

Type 2 diabetes and obesity co-occur in high prevalence among African-American women. The positive value placed on large body size has both historic and contemporary biosocial relevance. The maintenance of weight at medically recommended levels is a cornerstone of both prevention and treatment of Type 2 diabetes. This study of overweight, elderly, rural African-American women with 7 pe 2 diabetes found they generally preferred smaller body sizes compared to previous studies. Normal to slim body images as presented in a photographic array were selected as being more attractive, less likely to have diabetes and hypertension, healthier and to be more …

Hexagonal Lattice Of 10-Nm Magnetic Dots, L. Malkinski, R. E. Camley, Z. Celinski, T. A. Winningham, S. G. Whipple, K. Douglas

Faculty Bibliography 2000s

We have grown precisely ordered and precisely located arrays of ultra-small magnetic dots. The nanofabrication process is based on the use of a protein crystal etch mask which is used to create a hexagonal lattice of holes in Si substrates. An assembly of (Fe/Pd)(4) dots with the average dot size of 10 nm in diameter, 6.5 nm height, and an average separation between dot centers of 22 nm was grown using molecular-beam epitaxy. The dot locations are determined by the biological mask that is used to create ordered arrays of similar to4 nm deep holes in Si. Fe/Pd multilayers (1 …

Identification And Initial Characterization Of Three Novel Cyclin-Related Proteins Of The Human Malaria Parasite Plasmodium Falciparum, Anaïs Merckx, Karine Le Roche, Marie-Paule Nivez, Dominique Dorin, Pietro Alano, Gustavo J. Gutierrez, Angel R. Nebreda, Dean Goldring, Christina Whittle, Shelly Patterson, Debopam Chakrabarti, Christian Doerig

Faculty Bibliography 2000s

The molecular mechanisms regulating cell proliferation and development during the life cycle of malaria parasites remain to be elucidated. The peculiarities of the cell cycle organization during Plasmodium falciparum schizogony suggest that the modalities of cell cycle control in this organism may differ from those in other eukaryotes. Indeed, existing data concerning Plasmodium cell cycle regulators such as cyclin-dependent kinases reveal structural and functional properties that are divergent from those of their homologues in other systems. The work presented here lies in the context of the exploitation of the recently available P. falciparum genome sequence toward the characterization of putative …

Cloning Of Hbsag-Encoded Genes In Different Vectors And Their Expression In Eukaryotic Cells, Shan Qin, Hong Tang, Lian-San Zhao, Fang He, Yong Lin, Li Liu, Xiao-Mei He

Faculty Bibliography 2000s

AIM: To compare the efficiency of different plasmids as DNA vectors by cloning three HBsAg-encoded genes into two eukaryotic expression vectors, pRc/CMV and pSG5UTPL/Flag, and to express HBsAg S, MS, and LS proteins in SP2/0 cells, and to establish monoclone SP2/0 cell strains that are capable of expressing S or S2S proteins stably. METHODS: Segments of S, preS2-S, preS1-preS2-S genes of Hepatitis B virus were amplified by routine PCR and preS1-S fragment was amplified by Over-Lap Extension PCR. The amplified segments were cleaved with restricted endonuclease Hind III/Not I followed by ligation with pRc/CMV, or BamHI/EcoR I followed by ligation …

Attenuation Of Mycobacterium Tuberculosis By Disruption Of A Mas-Like Gene Or A Chalcone Synthase-Like Gene, Which Causes Deficiency In Dimycocerosyl Phthiocerol Synthesis, Tatiana D. Sirakova, Vinod S. Dubey, Michael H. Cynamon, Pappachan E. Kolattukudy

Faculty Bibliography 2000s

Tuberculosis is one of the leading preventable causes of death. Emergence of drug-resistant tuberculosis makes the discovery of new targets for antimyrobacterial drugs critical. The unique mycobacterial cell wall lipids are known to play an important role in pathogenesis, and therefore the genes responsible for their biosynthesis offer potential new targets. To assess the possible role of some of the genes potentially involved in cell wall lipid synthesis, we disrupted a mas-like gene, msl7, and a chalcone synthase-like gene, pks10, with phage-mediated delivery of the disruption construct, in which the target gene was disrupted by replacement of an internal segment …

The Largest Open Reading Frame (Pks12) In The Mycobacterium Tuberculosis Genome Is Involved In Pathogenesis And Dimycocerosyl Phthiocerol Synthesis, Tatianna D. Sirakova, Vinod S. Dubey, Hwa-Jung Kim, Michael H. Cynamon, Pappachan E. Kolattukudy

Faculty Bibliography 2000s

The cell wall lipids in Mycobacterium tuberculosis are probably involved in pathogenesis. The largest open reading frame in the genome of M. tuberculosis H37Rv, pks12, is unique in that it encodes two sets of domains needed to produce fatty acids. Apks12-disrupted mutant was produced, and disruption was confirmed by both PCR analysis and Southern blotting. Sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) analysis showed that a 430-kDa protein band present in the wild type was missing in the mutant. Matrix-assisted laser desorption ionization-time of flight mass spectrometry (MS) and liquid chromatography (LC)-MS analysis of tryptic peptides showed that 54 peptides distributed …

H. Wayne Huizenga School Of Business And Entrepreneurship 2003-2004 Catalog, Nova Southeastern University

Huizenga Postgraduate Course Catalogs

No abstract provided.

Psyc 649.01: Attachment And Attachment Disorders, Paul S. Silverman

University of Montana Course Syllabi

No abstract provided.

Psyc 536.01: Advanced Child And Adolescent Psychological Disorders, Paul S. Silverman

University of Montana Course Syllabi

No abstract provided.

Psyc 330.01: Abnormal Psychology, Jennifer D. Gottlieb

University of Montana Course Syllabi

No abstract provided.

Psyc 270.01: Fundamentals Of Biological Psychology, Stuart Hall

University of Montana Course Syllabi

No abstract provided.

Phar 644.01: Fundamentals Of Immunotoxicology, David M. Shepherd

University of Montana Course Syllabi

No abstract provided.