Digital Commons Network^™

Plasma Membrane Topology Of Syncytial Domains Of Herpes Simplex Virus Type 1 Glycoprotein K (Gk): The Ul20 Protein Enables Cell Surface Localization Of Gk But Not Gk-Mediated Cell-To-Cell Fusion, Timothy P. Foster, Xavier Alvarez, Konstantin G. Kousoulas

Faculty Publications

Most spontaneously occurring mutations that cause extensive herpes simplex virus type 1 (HSV-1)-induced cell fusion are single amino acid changes within glycoprotein K (gK). Despite the strong genetic association of gK with virus-induced cell fusion, its direct involvement in cellular membrane fusion has been controversial, largely due to previously unsuccessful efforts to detect gK expression on virion and cellular surfaces. Recently, we showed that gK is expressed on HSV-1 virions and functioned in virus entry (T. P. Foster, G. V. Rybachuk, and K. G. Kousoulas, J. Virol. 75:12431-12438, 2001). To determine whether gK is expressed on cellular surfaces, as well …

Natural Bovine Lentiviral Type 1 Infection In Holstein Dairy Cattle. I. Clinical, Serological, And Pathological Observations, T. G. Snider, B. F. Jenny, P. G. Hoyt, K. S. Coats, K. F. Graves, C. R. Cooper, R. W. Storts, D. G. Luther

Faculty Publications

Clinical, serological, and pathological abnormalities observed in Holstein cows naturally infected with bovine lentivirus 1 bovine immunodeficiency virus (BIV) and other infections were progressive and most commonly associated with weight loss, lymphoid system deficiency, and behavioral changes. Clinical evidence of meningoencephalitis was dullness, stupor, and occasional head or nose pressing postures. The polymerase chain reactions associated the BIV provirus with the lesions in the central nervous system and lymphoid tissues. Multiple concurrent infections developed in retrovirally infected cows undergoing normal stresses associated with parturition and lactation. A major functional correlate of the lymphoreticular alterations was the development of multiple secondary …

Allelic Heterogeneity In Line-1 Retrotransposition Activity, Sheila M. Lutz, Bethaney J. Vincent, Haig H. Kazazian, Mark A. Batzer, John V. Moran

Faculty Publications

De novo LINE-1 (long interspersed element-1, or L1) retrotransposition events are responsible for ∼1/1,000 disease-causing mutations in humans. Previously, L1.2 was identified as the likely progenitor of a mutagenic insertion in the factor VIII gene in a patient with hemophilia A. It subsequently was shown to be one of a small number of active L1s in the human genome. Here, we demonstrate that L1.2 is present at an intermediate insertion allele frequency in worldwide human populations and that common alleles (L1.2A and L1.2B) exhibit an ∼16-fold difference in their ability to retrotranspose in cultured human HeLa cells. Chimera analysis revealed …

Haplotypes In The Dystrophin Dna Segment Point To A Mosaic Origin Of Modern Human Diversity, Ewa Ziȩtkiewicz, Vania Yotova, Dominik Gehl, Tina Wambach, Isabel Arrieta, Mark Batzer, David E.C. Cole, Peter Hechtman, Feige Kaplan, David Modiano, Jean Paul Moisan, Roman Michalski, Damian Labuda

Faculty Publications

Although Africa has played a central role in human evolutionary history, certain studies have suggested that not all contemporary human genetic diversity is of recent African origin. We investigated 35 simple polymorphic sites and one Tn microsatellite in an 8-kb segment of the dystrophin gene. We found 86 haplotypes in 1,343 chromosomes from around the world. Although a classical out-of-Africa topology was observed in trees based on the variant frequencies, the tree of haplotype sequences reveals three lineages accounting for present-day diversity. The proportion of new recombinants and the diversity of the Tn microsatellite were used to estimate the age …

Effect Of Horn Fly (Haematobia Irritans) Control On Growth And Reproduction Of Beef Heifers, S. M. Derouen, L. D. Foil, A. J. Mackay, D. E. Franke, D. W. Sanson, W. E. Wyatt

Faculty Publications

The influence of horn fly control with commercially available ear tags was studied on beef replacement heifers (n = 670) for growth and reproductive performance. The study was conducted at five sites in Louisiana over 3 yr. Heifers used were yearling replacement females that were exposed to fertile bulls during a limited spring breeding season that coincided with the horn fly season. In mid to late May of each year, heifers were randomly assigned to one of two horn fly treatments: untreated and treated for horn fly control. The trial continued each year until September or October at the end …

L'Avocat : 2003, Louisiana State University Law Center

L’Avocat : The Louisiana State University Law Center Yearbooks

No abstract provided.

Strangers To The Constitution?: Resident Aliens, Military Tribunals, And The Laws Of War, Adeno Addis

Valparaiso University Law Review

No abstract provided.

Ethical, Legal, And Social Issues In Genetic Testing For Complex Genetic Diseases, Lori Andrews, Erin Shaugnessy Zuiker

Valparaiso University Law Review

No abstract provided.

When The Open Road Is Closed To Juveniles: The Constitutionality Of Juvenile Curfew Laws And The Inconsistencies Among The Courts, Cheri L. Lichtensteiger Baden

Valparaiso University Law Review

No abstract provided.

The Medical Necessity Defense And De Minimis Protection For Patients Who Would Benefit From Using Marijuana For Medical Purposes: A Proposal To Establish Comprehensive Protection Under Federal Drug Laws, Ronald Timothy Flether

Valparaiso University Law Review

No abstract provided.

Reverse Age Discrimination Under The Age Discrimination In Employment Act: Protecting All Members Of The Protected Class, Kelly J. Hartzler

Valparaiso University Law Review

No abstract provided.

The "Art" Of Inheritance: A Proposal For Legislation Requiring Proof Of Parental Intent Before Posthumously Conceived Children Can Inherit From A Deceased Parent's Estate, Melissa B. Vegter

Valparaiso University Law Review

No abstract provided.

Land And Liberation: Lessons For The Creation Of Effective Land Reform Policy In South Africa, Hasani Claxton

Michigan Journal of Race and Law

Based upon the premise that land reform is essential to creating socio-economic equality, easing racial tensions and stemming the tide of violence in South Africa, this note will provide suggestions for effective land reform policy. To accomplish this, this Note will examine the paths taken by several other transitional African governments in land reform policy. It will attempt to extract practical lessons from their experiences and apply them towards the development of effective land redistribution policy in South Africa. Part I of this note will provide a historical overview of colonialism and land law in Africa. Part II will examine …

Regulating Target Marketing And Other Race-Based Advertising Practices, Ross D. Petty, Anne-Marie G. Harris, Toni Broaddus, William M. Boyd Iii

Michigan Journal of Race and Law

Recognizing the significant role that advertising plays in American life, this article examines the phenomenon of race-based targeted marketing as a contributing factor to the racial tension of our media age and evaluates the role of government regulation in preventing the dissemination of racist messages through advertising. In Part I, the article first looks at the evolution of "mass" marketing into today's standard use of targeted marketing techniques, and especially how those techniques can sometimes have racist effects. In Part II, the article discusses both measurable and esoteric harms of cultural racism. Part III examines existing laws designed to regulate …

Power, Possibility And Choice: The Racial Identity Of Transracially Adopted Children, Twila L. Perry

Michigan Journal of Race and Law

Review of The Ethics of Transracial Adoption by Hawley Fogg-Davis

Bête Noire: How Race-Based Policing Threatens National Security, Lenese C. Herbert

Michigan Journal of Race and Law

This Article asserts that race-based policing, enabled and exacerbated by race-blind judicial review, creates an ire with a purpose that promises, especially after September 11, to make us all less safe. The illegitimate marginalization of American citizens aggravates an already alienated population and primes them for cooperation with those who seek to harm the United States. Race-based policing guts the expectation of fair-dealing, legitimacy, and justice in the criminal justice system, creating marginalized populations, especially of African Americans. Lack of judicial redress in the face of such policing irrevocably stains already beleaguered African Americans (and others so policed) as inferior …

Breaking The Camel's Back: A Consideration Of Mitigatory Criminal Defenses And Racism-Related Mental Illness, Camille A. Nelson

Michigan Journal of Race and Law

This article will examine the concept of racist words, symbols, and actions that are used as weapons to "ambush, terrorize, wound, humiliate, and degrade,” as psychological and physiological violence. The implications of such violence are relevant to several affirmative defenses and, indeed, to the initial formulation of mens rea. The historical and contextual legacy that is intentionally invoked by the utilization of racialized violence is what separates the racial epithet or racially violent symbolism from other distressing insults and slurs. While First Amendment protection extends to offensive or insulting speech, the mental and physical sequelae of such speech, even absent …

Utb/Tsc Commencement – Winter 2003, University Of Texas At Brownsville, Texas Southmost College

Brownsville Archives - Legacy Commencement Programs

No abstract provided.

The Failure Of Aviation Safety In New Zealand: An Examination Of New Zealand's Implementation Of Its International Obligations Under Annex 13 Of The Chicago Convention On International Civil Aviation, Samantha Sharif

Journal of Air Law and Commerce

No abstract provided.

Ninth Circuit Holds The General Aviation Revitalization Act Is Immediately Appealable Under The Collateral Order Doctrine: Estate Of Kennedy V. Bell Helicopter Textron, Inc., Carter Boisvert

Journal of Air Law and Commerce

No abstract provided.

Utb-Tsc Executive Summary - Faculty Satisfaction Survey, University Of Texas At Brownsville And Texas Southmost College. Faculty Senate.

UTB/TSC Faculty Senate Administrative Documents

No abstract provided.

Synthesis Of Montiporynes A And B, Traci Jenelle Speed

Honors Theses

This thesis reports the first complete synthesis of monriporynes A and B. isomeric diacetylenes that bear α, β unsaturated ketone functionalities. Recently isolated from the stony coral Montipora sp. these compounds are reported to possess in vitro cytotoxic activity against several human solid tumor cells. We have synthesized both isomers in three simple steps. In the first step, l-iodononyne was prepared by reacting 1-nonyne with N-iodosuccinimide and a catalytic amount of silver nitrate. This iodoalkyne was then coupled with propargyl alcohol using copper iodide as the catalyst to give 2,4dodecadiynyl alcohol. Finally, the diacetylenic alcohol was subjected to the Swern …

Quantitative Analysis Of Diepoxybutane Damage Within The Chicken Β-Globin Domain, André M. Pilon

Honors Theses

In industrial polymer and synthetic rubber production facilities, workers are exposed to 1,3-butadiene. This compound is converted in vivo to 1,2,3,4-diepoxybutane (DEB) and has been linked to increased incidences of cancer in these individuals. Carcinogenesis has been attributed to formation of DEB induced DNA interstrand cross-links. Previous studies have demonstrated that DEB cross-links deoxyguanosine residues within 5'-GNC sequences in synthetic DNA, in restriction fragments, and in defined sequence nucleosomes. The current study utilized the polymerase chain reaction (PCR) to examine DEB damage frequencies within nuclear genes, found within "open" regions of chromatin, as compared to regions of unexpressed sequence that …

Personal And Interpersonal Predictors Of Worry In Male And Female High School Students, Barbara Anne Davis

Masters Theses

This study identified which among several factors would best predict the tendency to worry in male and female adolescents. The potential predictors were divided into two different categories: personal and interpersonal factors. Personal factors included perfectionism, self-consciousness, and locus of control. Interpersonal factors included parental attachment, parenting style, and peer attachment.

Participants in the study completed several scales that measured the predictors. The data were then analyzed to determine the relative contribution of each factor in predicting worry, and to specify the factors that best predict worry. Gender differences in worry levels and in how the factors predicted worry were …

The Effects Of Practice With Decodable Texts On The Reading Fluency Of Low-Achieving First Grade Children, Nicole Forsythe

Masters Theses

This study examined the effect of a reading intervention using practice with decodable text on the reading fluency skills of four struggling first grade students. Participants received guided practice reading short decodable books twice a week for seven weeks. Pre and post-test standardized word reading scores were obtained using the Test of Word Reading Efficiency (TOWRE). Word reading fluency was assessed after each session by a list of words from the decodable texts. Results showed a marked improvement in each participant's fluency score, with all four participants at least doubling their baseline fluency as measured by words read accurately per …

Individual Phonological Awareness Training For Speech/Language Impaired First Graders, Sarah Weaver

Masters Theses

The purpose of the present study is to determine the effects of individual phonological awareness and phonics training emphasizing auditory, motoric, and alphabetic properties of phonemes with 3 children who did not make substantial gains following classroom phonological awareness intervention. Subjects were enrolled in the first grade and exhibited speech and/or language impairments. The individual phonological awareness program contained 3 parts: (1) phonological awareness, (2) phoneme-grapheme correspondence, and (3) decoding and spelling and employed a single subject multiple probe baseline across behaviors design. Results indicated that individual treatment was successful for teaching phonological awareness, phoneme-grapheme correspondence, and decoding and spelling. …

The Use Of Silence As A Political Rhetorical Strategy, Timothy J. Anderson

Masters Theses

Existing research on the rhetorical strategies of politicians has mainly focused on the speeches, appearances, and debates of political figures. Yet the absence of a clear response when expected, or silence, is a significant and frequently utilized rhetorical strategy. More directly, Erickson and Schmidt (1982) posit that, even though it is important to study, the topic of political silence has only received meager attention. Various politicians including President Clinton and California Congressman Gary Condit have both used political silence as responses to situations, and each instance had a different outcome. The focus of this study is on how the strategy …

Understanding Reflection, David Michael Moutray

Masters Theses

understanding reflection is a collection of poems which examines reflection both as an element of memory and self-image. The thirty-six poems represent devices and conventions employed by Philip Larkin, Donald Justice, Kamala Das, and Adrienne Rich. The style and voice mastered by these four poets served as an inspiring force in my creative efforts. The thesis introduction examines the voices of these poets and their influence on my work -- particularly in respect to my exploration of sexual, cultural and familial tensions.

The introductory essay, in essence, introduces my progression through reflection. Throughout the course of my progression, Larkin and …

Impact Of Service Delivery Model, Presenting Problem, And Consultee Characteristics On Teachers’ Preference For Academic And Behavioral Remediation, Kathy Wilson

Masters Theses

This study examined teachers' preferences for academic and behavioral remediation. Specifically, the impact of service delivery model (traditional or flexible), type of presenting problem (academic or behavioral), and selected consultee characteristics (age, years of experience, grade level taught, years at current school, and level of teacher education) on teacher preferences was investigated. Individuals completed a demographic information sheet and an analog study. The survey consisted of two hypothetical scenarios of two different students found within the classroom. The first scenario described a student who only exhibited behavioral/emotional issues. The second scenario described a student who presented with only academic issues. …

The Relationship Between Thigh Muscle Size And 1rm Squat Strength Among Bodybuilders, Powerlifters, And Olympic Weightlifters, James Dinaso

Masters Theses

The purpose of this study was to determine if a significant difference exists in the relationship between measures of muscle size and strength among elite bodybuilders, powerlifters, and Olympic weightlifters. Fifteen male subjects between the ages of 16 and 48 years participated in the study. All three subject groups, Olympic weightlifters (OWL, n=5), powerlifters (PL, n=5), and bodybuilders (BB, n=5), were highly trained and currently involved in competition training. All test subjects were of similar body weight and weighed between 76-96 kilograms. Measures of body weight, body composition (bioelectrical impedence), shoulder width, thigh circumference (proximal, distal, and mid-thigh), and thigh …