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Articles 5821 - 5850 of 8705
Full-Text Articles in Entire DC Network
Ethanol Consumption Decreases The Synthesis Of The Mannose 6-Phosphatelinsulin-Like Growth Factor Ii Receptor But Does Not Decrease Its Messenger Rna, James Haorah, Richard Macdonald, Julie A. Stoner, Terrence M. Donohue, Jr.
Ethanol Consumption Decreases The Synthesis Of The Mannose 6-Phosphatelinsulin-Like Growth Factor Ii Receptor But Does Not Decrease Its Messenger Rna, James Haorah, Richard Macdonald, Julie A. Stoner, Terrence M. Donohue, Jr.
United States Public Health Resources
The mannose 6-phosphatelinsulin-like growth factor I1 receptor (M6P/IGF-IIR) is a protein that facilitates the transport of acid hydrolases into the lysosome. We have shown that chronic ethanol consumption lowers the M6P/IGF-IIR content in rat hepatocytes. Here, we determined the steady-state level of mRNA encoding M6P/IGF-IIR, as well as the rate of receptor synthesis, to ascertain whether the ethanol-elicited reduction in receptor protein content is related to changes in either or both of these parameters. Rats were pair-fed the normal carbohydrate (NC) or low carbohydrate high-fat (LC) liquid diets containing either ethanol or isocaloric maltose-dextrin for 7-8 weeks. RNA was isolated …
Impaired Receptor-Mediated Endocytosis By The Asialoglycoprotein Receptor In Ethanol-Fed Mice: Implications For Studying The Role Of This Receptor In Alcoholic Apoptosis, Shana R. Dalton, Robert L. Wiegert, Cheryl R. Baldwin, Karen M. Kassel, Carol A. Casey
Impaired Receptor-Mediated Endocytosis By The Asialoglycoprotein Receptor In Ethanol-Fed Mice: Implications For Studying The Role Of This Receptor In Alcoholic Apoptosis, Shana R. Dalton, Robert L. Wiegert, Cheryl R. Baldwin, Karen M. Kassel, Carol A. Casey
United States Public Health Resources
During receptor-mediated endocytosis (RME), extracellular molecules are internalized after being recognized and bound to specific cell surface receptors. In previous studies of the asialoglycoprotein receptor (ASGPR) in rats, we showed that ethanol impairs RME at multiple ASGPR sites. Ethanol administration has been shown to increase apoptosis, and we demonstrated increased sensitization to apoptotic induction in hepatocytes from ethanol-fed rats. Although a physiological role for the ASGPR has not been identified, investigators have shown its involvement in the uptake/clearance of apoptotic cells in vitvo. This suggests a potential role for the ASGPR in the removal of apoptotic cells, and the recent …
Chronic Ethanol Consumption Impairs Receptor-Mediated Endocytosis Of Maa-Modified Albumin By Liver Endothelial Cells, Michael J. Duryee, Lynell W. Klassen, Thomas L. Freeman, Monte S. Willis, Dean J. Tuma, Geoffrey M. Thiele
Chronic Ethanol Consumption Impairs Receptor-Mediated Endocytosis Of Maa-Modified Albumin By Liver Endothelial Cells, Michael J. Duryee, Lynell W. Klassen, Thomas L. Freeman, Monte S. Willis, Dean J. Tuma, Geoffrey M. Thiele
United States Public Health Resources
Alcoholic liver disease has been associated with abnormalities in receptor-mediated endocytosis (RME) which results in abnormal degradation of metabolically altered proteins. Model systems using formaldehyde-modified albumin (f-Alb) have shown an impairment in RME following chronic alcohol consumption utilizing both in situ perfused rat livers and isolated rat liver endothelial cells (LECs). The discovery that alcohol metabolite derived aldehydes can modify proteins prompted a study to determine if malondialdehyde– acetaldehyde-modified albumin (MAA-Alb) would be degraded similar to that reported for f-Alb, and whether ethanol-fed rats would demonstrate an impaired RME with respect to this ligand which occurs as a consequence of …
Vulcan Historical Review 7 (Complete Issue), Vulcan Historical Review Staff
Vulcan Historical Review 7 (Complete Issue), Vulcan Historical Review Staff
Vulcan Historical Review
No abstract provided.
The Us Army And Women Soldiers: 1917-1945, Pamela E. Jones
The Us Army And Women Soldiers: 1917-1945, Pamela E. Jones
Vulcan Historical Review
pp. 53-74
Washington University Magazine, Spring 2003
Washington University Magazine, Spring 2003
Washington University Magazine
No abstract provided.
Undergraduate Catalog - The School Year 2002-2003, Prairie View A&M University
Undergraduate Catalog - The School Year 2002-2003, Prairie View A&M University
Undergraduate Catalog
No abstract provided.
Prevalence Of Chronic Wasting Disease And Bovine Tuberculosis In Free-Ranging Deer And Elk In South Dakota, Christopher N. Jacques, Jonathan A. Jenks, Allen L. Jenny, Steven L. Griffin
Prevalence Of Chronic Wasting Disease And Bovine Tuberculosis In Free-Ranging Deer And Elk In South Dakota, Christopher N. Jacques, Jonathan A. Jenks, Allen L. Jenny, Steven L. Griffin
Michigan Bovine Tuberculosis Bibliography and Database
Heads of hunter-harvested deer and elk were collected throughout South Dakota (USA) and within established chronic wasting disease (CWD) surveillance areas from 1997–2002 to determine infection with CWD and bovine tuberculosis (TB). We used immunohistochemistry to detect CWD-infected individuals among 1,672 deer and elk sampled via geographically targeted surveillance. A total of 537 elk (Cervus elaphus nelsoni), 813 white-tailed deer (Odocoileus virginianus), and 322 mule deer (O. hemionus) was sampled for CWD. Estimated overall prevalence and associated confidence intervals (95%) in white-tailed deer was 0.001% (0–0.007%). Similarly, estimated overall prevalence in elk and mule …
Mycobacterial Diseases In Wildlife, Gary Witmer, Thomas J. Deliberto, Kurt C. Vercauteren, Peter Butchko
Mycobacterial Diseases In Wildlife, Gary Witmer, Thomas J. Deliberto, Kurt C. Vercauteren, Peter Butchko
Michigan Bovine Tuberculosis Bibliography and Database
Mycobacterium infections occur in numerous wildlife species worldwide and this bacterial genus can also cause disease in humans and livestock. Two Mycobacterium species and one subspecies that infect wildlife are important from a wildlife damage management perspective. Mycobacterium avium, avian tuberculosis, is a ubiquitous and cosmopolitan disease of wild and domestic birds. Wild and domestic ruminants are host to M. avium paratuberculosis, also known as Johne’s disease. Finally, Mycobaterium bovis, bovine tuberculosis, is primarily associated with domestic and wild bovines and ungulates, but also infects many other species of mammals. Eradicating these diseases from wildlife populations is …
Mycobacterial Diseases In Wildlife, Gary W. Witmer, Thomas J. Deliberto, Kurt C. Vercauteren, Peter Butchko
Mycobacterial Diseases In Wildlife, Gary W. Witmer, Thomas J. Deliberto, Kurt C. Vercauteren, Peter Butchko
Michigan Bovine Tuberculosis Bibliography and Database
Mycobacterium infections occur in numerous wildlife species worldwide and this bacterial genus can also cause disease in humans and livestock. Two Mycobacterium species and one subspecies that infect wildlife are important from a wildlife damage management perspective. Mycobacterium avium, avian tuberculosis, is a ubiquitous and cosmopolitan disease of wild and domestic birds. Wild and domestic ruminants are host to M. avium paratuberculosis, also known as Johne’s disease. Finally, Mycobaterium bovis, bovine tuberculosis, is primarily associated with domestic and wild bovines and ungulates, but also infects many other species of mammals. Eradicating these diseases from wildlife populations is …
Aei News, Volume 1, Number 4, 2003, Asia-Europe Institute University Of Malaya
Aei News, Volume 1, Number 4, 2003, Asia-Europe Institute University Of Malaya
Archival Material (2000s)
No abstract provided.
Growth And Carcass Characteristics In Wether Lambs Of A Crossbred Dam Line, A. M. Van Heelsum, R. M. Lewis, M. H. Davies, W. Haresign
Growth And Carcass Characteristics In Wether Lambs Of A Crossbred Dam Line, A. M. Van Heelsum, R. M. Lewis, M. H. Davies, W. Haresign
Department of Animal Science: Faculty Publications
While crossing of specialized sire and dam breeds can be biologically efficient overall, a by-product is produced in the form of (crossbred) males of the dam line that are unwanted for breeding. In the UK sheep indusiru, most commercial females are first crosses between males of 'longwool' crossing sire breeds, predominantly the Biuefaced Leicester, and females of hill breeds. Genetic improvement of carcass quality in longwool breeds would benefit the surplus F1males as well asfilter through to tile terminal sire cross lambs produced by the F1ewes. As afirst step, this paper aims to describe thegrowth and …
The Changing Purposes Of Criminal Punishment: A Retrospective On The Last Century And Some Thoughts About The Next, Albert Alschuler
The Changing Purposes Of Criminal Punishment: A Retrospective On The Last Century And Some Thoughts About The Next, Albert Alschuler
Articles
No abstract provided.
Journals As A Feminist Playground, Mary Anne Case
The 'Necessary' History Of Property And Liberty, Richard A. Epstein
The 'Necessary' History Of Property And Liberty, Richard A. Epstein
Articles
No abstract provided.
Should Legal Rules Be Used To Redistribute Income?, David A. Weisbach
Should Legal Rules Be Used To Redistribute Income?, David A. Weisbach
Articles
No abstract provided.
Social Norms From Close-Knit Groups To Loose-Knit Groups, Lior Strahilevitz
Social Norms From Close-Knit Groups To Loose-Knit Groups, Lior Strahilevitz
Articles
No abstract provided.
The Empirical Side Of Law And Economics, William M. Landes
The Empirical Side Of Law And Economics, William M. Landes
Articles
No abstract provided.
Accommodating Emergencies, Eric A. Posner, Adrian Vermeule
Accommodating Emergencies, Eric A. Posner, Adrian Vermeule
Articles
No abstract provided.
Why Was Lochner Wrong, David A. Strauss
Natural Human Rights: The Perspective Of The Ius Commune, Richard H. Helmholz
Natural Human Rights: The Perspective Of The Ius Commune, Richard H. Helmholz
Articles
No abstract provided.
Christopher St. German And The Law Of Custom, Richard H. Helmholz
Christopher St. German And The Law Of Custom, Richard H. Helmholz
Articles
No abstract provided.
Indefinitely Renewable Copyright, Richard A. Posner, William M. Landes
Indefinitely Renewable Copyright, Richard A. Posner, William M. Landes
Articles
No abstract provided.
Constitutional Cases 2002: An Overview, Patrick J. Monahan, Nadine Blum
Constitutional Cases 2002: An Overview, Patrick J. Monahan, Nadine Blum
The Supreme Court Law Review: Osgoode’s Annual Constitutional Cases Conference
No abstract provided.
Shorebird Management During The Non-Breeding Season - An Overview Of Needs, Opportunities, And Management Concepts, Brian A. Harrington
Shorebird Management During The Non-Breeding Season - An Overview Of Needs, Opportunities, And Management Concepts, Brian A. Harrington
Wader Study Group Bulletin
No abstract provided.
Wader Studies For The 21st Century - Supporting International Conservation, Tony Fox
Wader Studies For The 21st Century - Supporting International Conservation, Tony Fox
Wader Study Group Bulletin
No abstract provided.
Cross-Seasonal And Cross-Disciplinary Studies Of Migratory Shorebirds, Silke Nebel, David B. Lank
Cross-Seasonal And Cross-Disciplinary Studies Of Migratory Shorebirds, Silke Nebel, David B. Lank
Wader Study Group Bulletin
No abstract provided.
Fitness, Demographic Rates And Managing The Coast For Wader Populations, John D. Goss-Custard
Fitness, Demographic Rates And Managing The Coast For Wader Populations, John D. Goss-Custard
Wader Study Group Bulletin
No abstract provided.
A Deep Structure Connection: Child Labor And The World Trade Organization, Sara Ann Dillion
A Deep Structure Connection: Child Labor And The World Trade Organization, Sara Ann Dillion
ILSA Journal of International & Comparative Law
I would like to begin my remarks by making two utterly contradictory statements with regard to the relationship, as I see it, between the global phenomenon of child labor, and the World Trade Organization (WTO).
The Hidden Cost Of Free Trade: The Impact Of United States World Trade Organization Obligations On United States Environmental Law Sovereignty, George Cavros
ILSA Journal of International & Comparative Law
It is well settled that international trade is an integral part of an ever- growing interdependent world economy.