Digital Commons Network^™

Creating An Online Tutorial And Pathfinder, Peter A. Hook

Articles by Maurer Faculty

Mr Hook explores the educational potential of Web-based tutorials and pathfinders. He discusses how the multimedia environment can effectively reach a broad range of learner types, explaining how the disciplines of infor- mation architecture and information visualization can contribute to designing a successful tutorial and pathfinder.

Effects Of High -Dose Chemotherapy On The Bone Marrow Microenvironment, Brett Matthew Hall

Graduate Theses, Dissertations, and Problem Reports (ETD)

The bone marrow microenvironment composed in part of stromal cells provides the niche in which normal hematopoiesis occurs. Hematopoiesis generates cellular components of the immune system and blood through proliferation and differentiation of multipotent hematopoietic stem cells (HSC). In preparation for bone marrow transplantation, radiation or chemotherapy treatment temporarily disrupts the balance of hematopoiesis as many HSC and progenitor cells are destroyed. Following treatment cessation, transplanted HSC and progenitor cells migrate, or "home", back to the bone marrow microenvironment and initiate productive hematopoiesis. While the mechanism of bone marrow homing is not completely understood, several soluble factors and adhesion molecules …

The Study Of Glucose-6-Phosphate Dehydrogenase (G6pd) Gene Regulation In Hepg2 Cells By Glucose Induction And The Study Of G6pd Mrna Localization By Fluorescent In Situ Hybridization (Fish)., Brian Nelson Griffith

Graduate Theses, Dissertations, and Problem Reports (ETD)

HepG2 cells were used as a model system to study the regulation of glucose-6- phosphate dehydrogenase (G6PD). Regulation of hepatic G6PD expression involves changes in the amount of G6PD pre-mRNA in the nucleus in the absence of changes in the transcription rate of the gene. G6PD expression is increased in HepG2 cells incubated with increasing glucose concentrations. G6PD mRNA is increased 3- to 4- fold by incubation in 25 mM glucose, as compared to 0 mM glucose. To determine the cis-acting element involved in this regulation, HepG2 cells were stably transfected with G6PD genomic DNA composed of exons 7 through …

Like A Bridge Over Colored Water: A Mathematical Review Of The Rainbow Bridge: Rainbows In Art, Myth, And Science, John A. Adam

Mathematics & Statistics Faculty Publications

Commenting on a recent book, the author discusses various views of the rainbow: its role in culture, its scientific description, and its mathematical theory.

Bringing Online Learning To Campus: The Hybridization Of Teaching And Learning At Brigham Young University, Gregory L. Waddoups, Scott L. Howell

Faculty Publications

The primary purpose of Brigham Young University (BYU) is to provide students with a combination of sacred and secular education often described as the BYU experience. Achieving this purpose is challenged by the rapid growth in Church membership and an enrollment cap of 30,000 students. To address these challenges, BYU sponsors the use of technology to bridge the gap between the increased Church membership and the number of students allowed under the enrollment caps. This institutional case study shows how these challenges have influenced the hybridization of teaching and learning for on campus (resident) and off campus (distance) students. It …

When Voluntary, Incentive-Based Controls Fail: Structuring A Regulatory Response To Agricultural Nonpoint Source Water Pollution, Douglas R. Williams

All Faculty Scholarship

This article is part of the Symposium, Sustainable Agriculture: Food for the Future. Recognizing that, to date, farms had largely escaped regulation under the Clean Water Act, and that agricultural nonpoint source pollution is a leading contributor to impaired water quality, this article advocates for a regulatory response to such pollution. It considers existing programs to control nonpoint source pollution and demonstrates that they are inadequate. The article makes three recommendations: (1) an increased federal regulatory presence is needed; (2) the costs of implementing nonpoint source controls should be distributed in a pragmatic way that recognizes the extraordinary organizational presence …

The National Wildlife Refuge System And The Hallmarks Of Modern Organic Legislation, Robert L. Fischman

Articles by Maurer Faculty

This article explores the origins and precise meaning of the term "organic act," which is widely used in public land law. The evolution in the meaning of the term reflects larger shifts in the role of legislation in public resource management. The article illustrates this with an analysis of the 1997 Refuge Improvement Act, a substantial revision of the charter for the Refuge System and the first major statute governing public land management enacted since the 1970s.

The Refuge System's "dominant use" regime is an important model for sustainable resource management. The article describes this regime in the context of …

A Lesson For Conservation From Pollution Control Law: Cooperative Federalism For Recovery Under The Endangered Species Act, Robert L. Fischman, Jaelith Hall-Rivera

Articles by Maurer Faculty

No abstract provided.

Introduction To Written Symposium On Public Health And International Law, David P. Fidler

Articles by Maurer Faculty

No abstract provided.

Bioterrorism, Public Health, And International Law, David P. Fidler

Articles by Maurer Faculty

No abstract provided.

Part 1: Structure, Stability And Reactivity Of Small Biologically-Active Organosulfur Compounds. Part 2: Generation Of Reactive Oxygen Species In The Enzymatic Reduction Of Chromium(Vi) And Arsenic(V) And Its Implications In Metal-Induced Carcinogenesis., Oluwarotimi Odunayo Olojo

Graduate Theses, Dissertations, and Problem Reports (ETD)

Structure, stability, kinetics and mechanisms of oxidation of some important organosulfur compounds (2-aminoethanethiolsulfuric acid, 4-methyl-3-thiosemicarbazide and thionicotinamide) have been investigated by using UV-VIS, NMR, stopped-flow, and qualitative analysis. Results obtained showed that oxidation occurs mainly at the reactive sulfur center of the molecules via successive addition of oxygen atoms. The oxidation of thionicotinamide, an important xenobiotic, gave different oxygenated products, depending on the oxidizing power of the oxidant used. The sulfinic acid of thionicotinamide is stable with mild oxidizing agents while stronger oxidants desulfurize the molecule to yield sulfate as observed with other organosulfur compounds studied. Mechanism of oxidation leading …

Gene Expression During Skeletal Muscle Development: Effect Of In Ovo Igf-1 Administration On Broiler Embryogenesis And Postnatal Myogenesis In The Mouse., Jennifer Jo Richter

Graduate Theses, Dissertations, and Problem Reports (ETD)

The Myogenic Regulatory Factor family (MRFs) is a family of transcription factors that plays a key role in the development of skeletal muscle. MRFs include Myo D, myf-5, myogenin, and MRF-4. Myo D and myf-5 are genes expressed during myoblast proliferation, whereas myogenin and MRF-4 are expressed during myotube formation and differentiation. Insulin-Like Growth Factor 1 (IGF-1) controls muscle development both embryonically and during postnatal growth and repair by inducing myoblast proliferation and muscle hypertrophy. We determined the mRNA expression patterns of the MRFs during muscle development of the chicken and the effect of recombinant human IGF-1 (rhIGF-1) on these …

Building The Beaver And Lake Erie Canal: The Politics Of Public Improvements In Pennsylvania, 1783-1845., William David Mccarthy

Graduate Theses, Dissertations, and Problem Reports (ETD)

Patterns of commerce and settlement in colonial America were shaped by watercourses and portages. Road building skills were primitive and boating represented the most effective means of moving bulk freight and passengers. Traders and frontiersmen leading the advance of European settlement into the Appalachian Mountains therefore adopted the shortest crossings between watersheds. Natural conditions in Pennsylvania did not promote an orderly advance westward and produced isolated clusters of settlement around Philadelphia and Pittsburgh, with small and widespread settlements in Northwest Pennsylvania. State leaders were hard pressed to define the limits of Pennsylvania until the end of the eighteenth century, and …

Land Use, Environmental Quality And Public Policy: Interactions And Implications For Agricultural Sustainability., Ramkumar Bendapudi

Graduate Theses, Dissertations, and Problem Reports (ETD)

Population growth, combined with economic growth have been primary causes of urban sprawl and increased pressure on natural resources. Urban development often adversely affects land, water and air quality. Although not considered a threat to the nation's food production, land development and urbanization are critical issues because they can lead to fragmentation of agricultural and forest lands, loss of prime farmland, wildlife habitat and other resources, additional infrastructure costs for communities and regional authorities, and competition for water. These losses raise concerns about sustainability of land and agriculture. Various state-sponsored programs such as Purchase of Developmental Rights and Transfer of …

The Impact Of A Language Learning Context On Chinese Students Learning English., Saundra Enany Faris

Graduate Theses, Dissertations, and Problem Reports (ETD)

The purpose of this study was to examine English language acquisition in four ESL children whose native country is China. Each of the four children was considered individually and holistically through case study methodology, and some comparisons across children were considered. A second purpose of this study was to look holistically at the instructional strategies used to support language acquisition for each of these students. In addition, this research investigated the perceptions of the four Chinese ESL students regarding strategies and instructional methods used to facilitate English language acquisition at one or two elementary schools in a rural state in …

The Significance Of Metallothionein Isoform 3 Gene Expression In Human Prostate Cancer., Rana Dutta

Graduate Theses, Dissertations, and Problem Reports (ETD)

Since the expression of the brain specific metallothionein isoform, MT-3, was shown to be expressed in many, but not all prostate cancers, this gene was transfected into the commonly utilized prostate tumor cell line, PC-3, to study the consequence of MT-3 expression on growth rate and resistance to chemotherapeutic agents. PC-3 cells were stably transfected with MT-3 or MT-1E under control of the constitutive CMV promoter. The levels of MT-3 protein for the 5 overexpressing clones had an average level of 8.3 ng MT-3 per μg protein as assessed by quantitative immunodot blot analysis, and three were picked for further …

The Relationship Between West Virginia School Principals' Self-Perceived Brain Hemispheric Cognitive Styles/Leadership Styles And Identified Schools Of Excellence., James Perry Varner

Graduate Theses, Dissertations, and Problem Reports (ETD)

The purpose of this study was to identify the predominant self-perceived brain hemispheric cognitive styles and leadership styles of principals of schools identified as a West Virginia School of Excellence and to compare these with principals of schools that have not been identified as a West Virginia School of Excellence. The following research questions provided the focus for this study: Is there a difference between West Virginia principals of schools identified as a West Virginia School of Excellence and principals of schools not identified as a School of Excellence who perceive themselves as: (1) Right brain hemispheric cognitive style and …

Identifying And Comparing Misconceptions Held By American And Russian University Students In Mechanics, Alexandra Sokolova

Dissertations and Theses @ UNI

This paper reports on a study of misconceptions held by undergraduate students completing an introductory physics course at the University of Northern Iowa and first-year undergraduate students taking a mechanics course at the Herzen State Pedagogical University of Russia. Existence of misconceptions in mechanics among Russian and American students was investigated prior to instruction and at the completion of the one-semester course. Different teaching approaches were used to introduce the students to mechanics. An activity-based approach was emphasized at UNI and a traditional lecture-lab approach was used at Herzen University. The emphasis of the study was placed on identifying misconceptions …

Does Literature Work As Social Science? The Case Of George Orwell, Richard A. Epstein

University of Colorado Law Review

No abstract provided.

The National Energy Policy: Assessing Energy Policy Changes, Gary C. Bryner

University of Colorado Law Review

No abstract provided.

Sustaining Geographies Of Hope: Cultural Resources On Public Lands, Sandra B. Zellmer

University of Colorado Law Review

No abstract provided.

The Rio Grande Silvery Minnow And The Endangered Species Act, Sean O'Connor

University of Colorado Law Review

No abstract provided.

An End To Gene Patents? The Human Genome Project Versus The United States Patent And Trademark Office's 1999 Utility Guidelines, Mary Breen Smith

University of Colorado Law Review

No abstract provided.

Activism Is Not A Four-Letter Word, Rebecca L. Brown

University of Colorado Law Review

No abstract provided.

Effect Of Tio₂-Mediated Photocatalytic Degradation On The Toxicity Of Orange Ii, Arnaud Eric Nicolas Goutard

Dissertations and Theses @ UNI

C.I. Acid Orange 7 (15510) is the sodium salt of p-[(2-hydroxy-1-naphtalenyl)azo] benzenesulfonic acid. This azo dye is commonly known as Orange II and has been used to dye soaps, shoes, wood and paper (Ramchandani et al., 1994). In the United States and Europe, this dye is not allowed in foodstuffs. The purpose of this study is to investigate the efficiency of a TiO2-mediated photocatalytic oxidation process to degrade Orange II and to determine if Orange II is cytotoxic to certain types of cells. The role of UV radiation and TiO2 particles were examined, as well as the importance of oxygen …

The Effects Of An Interactive Computerized Multimedia Tutorial On Knowledge Gain In Modular Fixturing Design Concepts, Veekit O'Charoen

Dissertations and Theses @ UNI

This study was designed to compare student knowledge gain from learning modular fixturing design concepts by computer tutorial versus traditional lecture. The use of computer tutorial to support engineering and technology classroom instructions has been a major issue for many studies. The undergraduate curricula in engineering and technology are becoming increasingly complex due to the today's modern wide variety of manufacturing processes. The concept of modular fixturing in tool design course is one of the technical competencies which most industries would like graduates to be able to apply their knowledge to real-world problems and situations.

An interactive computerized multimedia tutorial …

A Simulation Program For Electronics Skill Knowledge Instruction At A Selected Community College In Taiwan, Hung-Jen Chen

Dissertations and Theses @ UNI

Since computers came into existence, simulations have been associated with it as the two inseparable media, simulations and computers, have had a mutually beneficial effect. With the advent of the flexible microcomputer, simulation has been widely used. In recent years, computer technology has infiltrated every sector in society, especially the educational system and industrial operations where simulations are essential for satisfying both instructional and industrial needs. Simulation effectiveness research has been mixed in both the educational system and industries. Therefore, it is still necessary to evaluate how effective computer simulation is as an instructional method or strategy.

This study was …

Étude Préliminaire De La Friction Des Planchers Recouverts De Matière Grasse, André Massicotte, François Quirion

Rapports de recherche scientifique

Au cours des cinq dernières années, les chutes par glissades ont été la cause de plus de 32000 cas de lésions professionnelles au Québec. Ce type d’accidents est généralement associé à une mauvaise résistance au glissement des planchers, particulièrement dans les services alimentaires où les planchers sont exposés à la matière grasse.

De juin à novembre 2001, QInc a réalisé une étude préliminaire visant à évaluer l’impact de l’entretien et de l’encrassement sur la résistance au glissement des planchers de grès exposés à la matière grasse et à l’usure depuis plusieurs années.

Une procédure a été mise au point afin …

Comparaison De L'Implantation D'Une Démarche D'Ergonomie Participative Et D'Outils D'Analyse Du Travail Destinés Aux Tâches Variées Dans Deux Entreprises Au Contexte Différent, Marie St-Vincent, Chantal Tellier, Denise Chicoine, Marie Laberge

Rapports de recherche scientifique

L’étude présente les résultats d’implantation d’une démarche participative visant l’analyse de tâches variées dans deux entreprises au contexte différent : l’une au contexte favorable à cette approche (usine 2), l’autre au contexte peu favorable (usine 1). Dans les deux entreprises, la structure d’intervention était basée sur un groupe d’ergonomie formé d’opérateurs et de spécialistes techniques; ce comité était encadré tout au long de l’intervention par des ergonomes et chapeauté par un comité de suivi, constitué de représentants de la direction et du syndicat.

Le projet a été réalisé en fonction de quatre objectifs :

1. transformer des situations de travail à …

La Pratique D'Intervention En Santé, En Sécurité Et En Ergonomie Dans Des Projets De Conception : Étude D'Un Cas De Conception D'Une Usine, Fernande Lamonde, Philippe Beaufort, Jean-Guy Richard

Rapports de recherche scientifique

Ce rapport s’adresse à ceux qui, dans les entreprises, firmes de consultants ou autres, sont impliqués dans la gestion ou interviennent directement en SST et en ergonomie : les directions d’entreprise, les responsables des méthodes et de la production, les chargés de projet (ingénieurs, informaticiens, architectes) de même que les préventionnistes et les ergonomes eux-mêmes.

Il relate la démarche originale qui a été mise en place pour intégrer la SST et l’ergonomie dans un projet de conception d’une usine réalisé au Québec de 1996 à 2002. Cette démarche a été reconstituée en analysant l’activité des deux préventionnistes et de l’ergonome …