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Articles 48931 - 48960 of 55115
Full-Text Articles in Entire DC Network
B2b Portal: Web-Enable Fulfillment System, Oi Ching Wong
B2b Portal: Web-Enable Fulfillment System, Oi Ching Wong
Student Works (2000-2009)
The Web-enable fulfillment system is basically a web site that enables suppliers to automate and structure the order fulfillment process to help ensure that products and services meet or exceed customer’s exact requirements including quality, quantity and specifications. The intelligence of the system will be the server where all calculations and business rules are applies. Business-to-business (B2B) e-Commerce implies that both the sellers and buyers are business corporation. Purchase order is used as the system default as the business partners rarely use credit card for payment. Therefore, the order fulfillment process begins when an approved order is routed to the …
Teucrium Polium Inhibits Nerve Conduction And Carrageenan Induced Inflammation In The Rat Skin, Jumah Shakhanbeh, O. Adigüzel
Teucrium Polium Inhibits Nerve Conduction And Carrageenan Induced Inflammation In The Rat Skin, Jumah Shakhanbeh, O. Adigüzel
Turkish Journal of Medical Sciences
The effects of acute and chronic perineural treatment of the rat saphenous nerve with Teucrium polium (L.) extract on the conduction property of primary afferent nerve fibers and carrageenan-induced skin inflammation were studied. Direct application of 2.0% T. polium extract to the nerve trunk caused immediate complete inhibition of compound action potentials (CAPs) of all types of primary afferent nerve fibers. Partial recovery of CAPs was seen in up to 37.5% of Aab-fibers, 30.4% of Ad-fibers and 32.4% for C-fibers over one hour after removal of the extract. Fifteen to twenty days after a single perineural application of 2% T. …
The Antioxidant Activity Of The Leaves Of Cydonia Vulgaris, Ali̇ Yildirim, Müni̇r Oktay, Vahi̇t Bi̇laloğlu
The Antioxidant Activity Of The Leaves Of Cydonia Vulgaris, Ali̇ Yildirim, Müni̇r Oktay, Vahi̇t Bi̇laloğlu
Turkish Journal of Medical Sciences
The antioxidant activities of water, ethanol, and ether extracts of the leaves of Cydonia vulgaris Pers. were determined by the thiocyanate method. The antioxidant activity of water extract was increased with the increasing amount of extract (200 µg-1000µg) added to the linoleic acid emulsion. Ether extract was the most effective antioxidant among the extracts. Like antioxidant activity, the reducing power of water extract was concentration dependent. However, ethanol extract was the highest in reducing power, and ether extract was the lowest. The results obtained in the present study indicate that the leaves of Cydonia vulgaris are a potential source of …
A Relation Between The Apolipoprotein E Genotypes And Microalbuminuria In Type 2 Diabetes Mellitus, Ersi̇n Akarsu, İbrahi̇m Pi̇ri̇m, İlyas Çapoğlu, Hasan Kaya, Güngör Akçay, Necdet Ünüvar
A Relation Between The Apolipoprotein E Genotypes And Microalbuminuria In Type 2 Diabetes Mellitus, Ersi̇n Akarsu, İbrahi̇m Pi̇ri̇m, İlyas Çapoğlu, Hasan Kaya, Güngör Akçay, Necdet Ünüvar
Turkish Journal of Medical Sciences
Various relations between apolipoprotein E (apo E) and diabetic nephropathy have been reported. In this study, the question of whether there is any relation between apo E genotypes and microalbuminuria in patients with type-2 diabetes mellitus was examined. Twenty-one male and 25 female patients, with ages the range of 37-62 years (mean 51.7±7.5) with type-2 diabetes mellitus were studied. The apo E genotypes were determined by PCR amplification of the 227 bp region followed by CfoI digestion to release specific band patterns. While 24 patients had microalbuminuria (microalbuminuria group), 22 patients had normoalbuminuria (normoalbuminuria group). The patients with microalbuminuria had …
Expression Of The 8 Kda Heat Shock Protein (Ubiquitin) In Psoriasis, İbrahi̇m Pi̇ri̇m, Teoman Erdem, Necmetti̇n Akdeni̇z, Yaşar Nuri̇ Şahi̇n
Expression Of The 8 Kda Heat Shock Protein (Ubiquitin) In Psoriasis, İbrahi̇m Pi̇ri̇m, Teoman Erdem, Necmetti̇n Akdeni̇z, Yaşar Nuri̇ Şahi̇n
Turkish Journal of Medical Sciences
The 8kDa protein (ubiquitin) is a member of the small heat shock protein (hsb) family. Ubiquitin may additionally be involved in the pathogenesis of various diseases. Intracellular accumulation of ubiquitin has been detected in patients with neurodegenerative disease, brain ischemia, cancer, rheumatoid arthritis and haemodialysis. Sixteen biopsy samples from patients with psoriasis who were treated by PUVA and the same samples from these patients before PUVA treatment were investigated by immunohistochemistry on formalin-fixed paraffin- embedded tissue sections, using anti-ubiquitin antibody. In psoriatic epidermis, ubiquitin was mostly expressed in basal layers with a cytoplasmic staining pattern. Various cells of the dermis …
Pulmonary Infections Due To Legionella Pneumophila In Immunocompromised Patients, Demet Kaya, Si̇nan Ergi̇nel, Muzaffer Meti̇ntaş, Zeki̇ Üstüner, İrfan Uçgun, Necla Özdemi̇r
Pulmonary Infections Due To Legionella Pneumophila In Immunocompromised Patients, Demet Kaya, Si̇nan Ergi̇nel, Muzaffer Meti̇ntaş, Zeki̇ Üstüner, İrfan Uçgun, Necla Özdemi̇r
Turkish Journal of Medical Sciences
The numbers of immunocom-promised individuals increase as programmes for organ transplantation and chemotherapy of malignant disease advance. Pulmonary infections, which progress rapidly, are one of the major clinical problems in these groups. This study was designed to evaluate the microbiology of pneumonia in immunocompromised patients and to determine the role of Legionella pneumophila. Immunocompromised patients receiving antineoplastic chemotherapy, diagnosed as pneumonia with clinical and radiographic findings and routine laboratory tests were included in the study. For microbiological diagnosis, expectorated sputum was cultured for L. pneumophila. In addition to standard bacterial, fungal and mycobacterial media, specimens were examined microscopically. Direct flourescent …
Perioperative Oral Supplement With Immunonutrients In Gastrointestinal Cancer Patients, Ni̇hal Zeki̇ye Erdem, İ. Hakan Kulaçoğlu, Mehtap Akci̇l Temel, Ahmet Çinar Yasti, Nuri̇ Aydin Kama, Nazan Bozkurt
Perioperative Oral Supplement With Immunonutrients In Gastrointestinal Cancer Patients, Ni̇hal Zeki̇ye Erdem, İ. Hakan Kulaçoğlu, Mehtap Akci̇l Temel, Ahmet Çinar Yasti, Nuri̇ Aydin Kama, Nazan Bozkurt
Turkish Journal of Medical Sciences
Significant benefits have been gained with pre or peri-operative nutritional support in surgical patients with malnutrition. Recent studies have also shown that some enteral formulas including certain nutrients like glutamine could provide more benefit than the standard formulas. In this prospective-randomized study, the effects of perioperative oral supplement with enteral formulas containing glutamine in comparison with a standard enteral formula in patients who were operated on for GI malignancies were examined. Thirty-two patients were divided into two groups: the study group was given oral supplement with an elemental diet (Alitraq®) for 7 days preoperatively and 10 days postoperatively as 30-35% …
Observations Of The Changes Occurring In The Rat Trachea Due To Inhalation Of Cigarette Smoke, Aysel Kükner, Hakan Öner, Neri̇man Çolakoğlu, Jale Öner, Enver Ozan, Sema Ozan, Seval Yilmaz
Observations Of The Changes Occurring In The Rat Trachea Due To Inhalation Of Cigarette Smoke, Aysel Kükner, Hakan Öner, Neri̇man Çolakoğlu, Jale Öner, Enver Ozan, Sema Ozan, Seval Yilmaz
Turkish Journal of Medical Sciences
In this study, the tracheal tissues of rats inhaling cigarette smoke passively during different periods were examined by light and electron microscopy. Malonaldehyde, erythrocyte catalase and arginase levels were also measured. Three groups were formed and a total of 15 Wistar male rats weighing 200-250 g were used. Rats assigned to the first and second groups were made to inhale cigarette smoke for 30 and 60 minutes respectively for a total of 3 months. The subjects in the third group were made to inhale clean air as a control. Cigarettes without filter tips were used througout the study. Lit cigarettes …
Smooth Muscle Actin (Sma) Immunoreactivity In Primary Glomerulonephritis (Gn), Duygu Düşmez, Gülfi̇li̇z Gönlüşen, Emel Akoğlu, Sevgi̇ Küllü, İlhan Tuncer
Smooth Muscle Actin (Sma) Immunoreactivity In Primary Glomerulonephritis (Gn), Duygu Düşmez, Gülfi̇li̇z Gönlüşen, Emel Akoğlu, Sevgi̇ Küllü, İlhan Tuncer
Turkish Journal of Medical Sciences
The aims of this study were to determine the role of interstitial and glomerular myofibroblasts in the progression of various glomerulonephritis, and to assess the value of myofibroblasts in determining long-term renal outcome. The biopsy specimens of 42 primary glomerulonephritis cases were reviewed and stained immunohistochemically with alpha smooth muscle actin antibody. The serum creatine level was compared to the pathological changes. The interstitial alpha smooth muscle actin staining correlated with the serum creatine level at the time of biopsy. The glomerular staining, conversely, did not show any relation with renal function. Interstitial myofibroblasts play a role in the development …
A Study On The Rat Stapedial Artery Under The Dissection Microscope, Cahi̇de Ortuğ
A Study On The Rat Stapedial Artery Under The Dissection Microscope, Cahi̇de Ortuğ
Turkish Journal of Medical Sciences
The stapedial artery is a rare anomaly in man. However, an undetected persistence of the artery may cause problems during middle ear surgery. The studies on its course are inadequate. The aim of the present paper is to describe the course of the stapedial artery in rats, through an examination under a dissection microscope.
The Effect Of Sulfur Dioxide On T-Butyl Hydroperoxide Induced Oxidative Stress In Lung Tissues Of Rats, Saadet Gümüşlü, Di̇jle Ki̇pmen Korgun, Süreyya Bi̇lmen, Gülteki̇n Yücel, Pi̇raye Yargiçoğlu, Aysel Ağar
The Effect Of Sulfur Dioxide On T-Butyl Hydroperoxide Induced Oxidative Stress In Lung Tissues Of Rats, Saadet Gümüşlü, Di̇jle Ki̇pmen Korgun, Süreyya Bi̇lmen, Gülteki̇n Yücel, Pi̇raye Yargiçoğlu, Aysel Ağar
Turkish Journal of Medical Sciences
In this study, the effects of sulfur dioxide (SO_2) ,a common pollutant in urban air, on t-butyl hydroperoxide-induced oxidative stress in rat lung tissues were examined. Ten young rats and 10 adult rats were exposed to SO_2 while another 10 young rats and 10 adult rats made up the control groups. Ten ppm SO_2 was administered to the animals of the SO_2 groups in an exposure chamber for one hour a day every day for 6 weeks. The control groups were exposed to filtered air in the same chamber for the same period. At the end of the experimental period, …
In Vivo Interaction Between Cadmium And Essential Trace Elements Copper And Zinc In Rats, H. Hakan Aydin, Canan Çoker, Bi̇ltan Ersöz
In Vivo Interaction Between Cadmium And Essential Trace Elements Copper And Zinc In Rats, H. Hakan Aydin, Canan Çoker, Bi̇ltan Ersöz
Turkish Journal of Medical Sciences
The complex in vivo interaction between Cd, a toxic metal and essential trace elements, mainly Zn and Cu, has not been elucidated yet. The objective being the elucidation of this interrelationship, Cd was subcutaneously administered as CdCI_2 (1 mg/kg/day) for 5 consecutive days to Swiss albino male rats (n=10). After 5 days, the rats were decapitated. Cd, Zn and Cu levels were estimated in hepatic, renal, cardiac and skeletal muscle specimens. Cd was found to be significantly elevated in all tissues (p< 0.001). Zn was increased in hepatic and renal tissues (p< 0.001 and p< 0.05) compared to the controls. Cu was also significantly increased in these tissues. Myocardial and skeletal muscle tissues also manifested a significant increase in Cu and Zn in this group. It is concluded that Cd administration alters the Zn and Cu status in vivo. However, the mechanism underlying the interactions between toxic and essential elements should be further investigated.
Immunohistochemical Expression Of C-Erb-B2, Steroid Receptors And Cathepsin-D In Breast Carcinomas: A Clinicopathologic Trial, Hadi̇ce Eli̇f Peştereli̇, Okan Erdoğan, Bahar Kiliçarslan, Taner Çolak, Evren Tercan, Mustafa Akaydin, Şeyda Karaveli̇
Immunohistochemical Expression Of C-Erb-B2, Steroid Receptors And Cathepsin-D In Breast Carcinomas: A Clinicopathologic Trial, Hadi̇ce Eli̇f Peştereli̇, Okan Erdoğan, Bahar Kiliçarslan, Taner Çolak, Evren Tercan, Mustafa Akaydin, Şeyda Karaveli̇
Turkish Journal of Medical Sciences
Aim: We investigated the role of c-erb-B2, hormone receptors and cathepsin D in breast carcinoma progression and their correlation with each other. Methods: Forty-six breast carcinoma patients, operated on in the deparment of surgery and diagnosed in the pathology department, were classified according to their histopathological characteristics; the results of immunostaining with estrogen and progesterone receptors, c-erb-B2 and cathepsin-D were correlated with the stage and the disease-free survival of the patients. Results: Nuclear positivity was observed in 23 (50 %) cases for estrogen receptor and in 16 (34.8 %) cases for progesterone receptor. There was membranous staining with c-erb-B2 in …
The Short-Term Results Of Intensive Insulin Therapy In Preadolescent Children With Type-1 Diabetes, Ayşenur Ökten, Gülay Kaya, Mukaddes Doğan Kalyoncu, Gamze Çan
The Short-Term Results Of Intensive Insulin Therapy In Preadolescent Children With Type-1 Diabetes, Ayşenur Ökten, Gülay Kaya, Mukaddes Doğan Kalyoncu, Gamze Çan
Turkish Journal of Medical Sciences
Purpose: The aim of this study was to observe the effects of and compliance with an intensive insulin regimen in preadolescent children with type-1 diabetes. Patients and methods: Eleven insulin-dependent diabetic patients, five girls and six boys aged 8 - 11 years (mean 9 years 3 months) with a mean±SD diabetes duration of 2±1.07 years, participated in this study. The results of the intensive insulin regimen were evaluated after one-year follow-up in 11 patients, and in 8 patients at 18 months. In the first year of this study we aimed to bring about higher blood glucose than is generally advised, …
Lung Functions In Workers Exposed To Tobacco Dust, Ahmet Tevfi̇k Sünter, Faruk Bağirici, Ci̇had Dündar, Abdullah Marangoz, Yildiz Pekşen
Lung Functions In Workers Exposed To Tobacco Dust, Ahmet Tevfi̇k Sünter, Faruk Bağirici, Ci̇had Dündar, Abdullah Marangoz, Yildiz Pekşen
Turkish Journal of Medical Sciences
Workers in the tobacco industry are exposed to tobacco dust, which has allergenic and irritative effects on airways. In this study, our aim was to determine whether tobacco dust has any effect on lung functions and volumes. A questionnaire about working conditions was applied to 448 workers, some of which had been exposed to tobacco dust while others had not, and all workers underwent measurements of spirometric flow and volume. Of the study group, 126 workers were exposed to tobacco dust for more than 10 years and 55 were not. All of these 181 workers were also nonsmokers. There were …
Fetal 45,X/46,Xy Mosaicism, Cytogenetic And Morphologic Findings In Pregnancy, Murat Derbent, Banu Bi̇lezi̇kçi̇, İdi̇l Alpas, Volkan Baltaci
Fetal 45,X/46,Xy Mosaicism, Cytogenetic And Morphologic Findings In Pregnancy, Murat Derbent, Banu Bi̇lezi̇kçi̇, İdi̇l Alpas, Volkan Baltaci
Turkish Journal of Medical Sciences
No abstract provided.
Irreversible Blindness: An Unusual Complication Of The Caldwell-Luc Operation, Gülhanim Haciyakupoğlu, Müsli̇me Yalaz, Altan Atakan Özcan, Erol Aksungur
Irreversible Blindness: An Unusual Complication Of The Caldwell-Luc Operation, Gülhanim Haciyakupoğlu, Müsli̇me Yalaz, Altan Atakan Özcan, Erol Aksungur
Turkish Journal of Medical Sciences
No abstract provided.
A Case Of Malignant Hyperthermia During Sevoflurane Anesthesia, Si̇bel Bariş, Deni̇z Karakaya, Fuat Güldoğuş, Bi̇nnur Sarihasan, Ati̇lla Tekat
A Case Of Malignant Hyperthermia During Sevoflurane Anesthesia, Si̇bel Bariş, Deni̇z Karakaya, Fuat Güldoğuş, Bi̇nnur Sarihasan, Ati̇lla Tekat
Turkish Journal of Medical Sciences
No abstract provided.
Hibernoma: A Case Report And Discussion Of A Rare Tumor, Mustafa Kösem, Meti̇n Karakök
Hibernoma: A Case Report And Discussion Of A Rare Tumor, Mustafa Kösem, Meti̇n Karakök
Turkish Journal of Medical Sciences
No abstract provided.
Sialolithiasis (Salivary Stone), Mehmet Dalkiz, Necdet Doğan, Bedri̇ Beydemi̇r
Sialolithiasis (Salivary Stone), Mehmet Dalkiz, Necdet Doğan, Bedri̇ Beydemi̇r
Turkish Journal of Medical Sciences
No abstract provided.
Restriction Fragment Length Polymorphism Analysis (Rflp) Of Some Streptomyces Strains From Soil, Ekrem Atalan
Restriction Fragment Length Polymorphism Analysis (Rflp) Of Some Streptomyces Strains From Soil, Ekrem Atalan
Turkish Journal of Biology
To separate the unknown Streptomyces strains isolated from soil samples, the interspacer regions of 16S-23S rDNA of 14 isolates were amplified with PCR (polymerase chain reaction) and digested with three restriction endonucleases, namely, Bsp143I, HaeIII and MnlI. The restriction patterns were used for RFLP (restriction fragment length polymorphism) analysis. A dendrogram were constructed using the unweighed pair group method using arithmetic averages algorithm (UPGMA) after analysis restriction patterns. Five RFLP groups were obtained anone test strain was left as a single member group. RFLP profile indicated that unknown strains could be identified with data based on the interspacer region of …
Effect Of Boron Application On The Yield And Quality Of Sugar Beet, Sai̇t Gezgi̇n, Mehmet Hamurcu, Mustafa Apaydin
Effect Of Boron Application On The Yield And Quality Of Sugar Beet, Sai̇t Gezgi̇n, Mehmet Hamurcu, Mustafa Apaydin
Turkish Journal of Agriculture and Forestry
This research was conducted to determine the effects of application methods and the levels of boron on the root yield and quality of sugar beet in the Konya-Altınekin plain. The experimental soil was sandy loam, poor in organic matter and rich in calcium carbonate. The soil was alkaline in reaction and sufficient in boron content (0.55 ppm). In this work, three different levels of boron in borax form (0, 0.3 and 0.6 kg B/da) were applied with five different methods (soil, leaf, seed, soil + leaf, seed + leaf). The results showed that the root yield and refined sugar yield …
In Vitro Plantlet Regeneration From Mature Embryos Of Linden (Tilia Platyphyllos Scop.) And Multiplication Of Its Buds, Ali̇ Ömer Üçler, Nuray Mollamehmetoğlu
In Vitro Plantlet Regeneration From Mature Embryos Of Linden (Tilia Platyphyllos Scop.) And Multiplication Of Its Buds, Ali̇ Ömer Üçler, Nuray Mollamehmetoğlu
Turkish Journal of Agriculture and Forestry
In this study, the effects of different sucrose, BAP and Kinetin concentrations in MS medium on plantlet formation, bud formation on the plantlets and development of embryos isolated from the seeds of Tilia platyphyllos under in vitro conditions were investigated. In addition, the effects of different culture times on the development of embryos and plantlet formation were studied. The results indicated that the cultured embryos on the media supplemented with sucrose (10, 20, 30, 40, 50 and 60 g/l) developed plantlets with epicotyls and roots. The best results were obtained on the medium supplemented with 30 g/l of sucrose. Epicotyls …
The Determination Of Some Physical Properties Of Beech Wood (Fagus Orientalis Lipsky.) In The Andırın Region, İbrahi̇m Bektaş, Cengi̇z Güler
The Determination Of Some Physical Properties Of Beech Wood (Fagus Orientalis Lipsky.) In The Andırın Region, İbrahi̇m Bektaş, Cengi̇z Güler
Turkish Journal of Agriculture and Forestry
The main aim of this study was to determine some physicals properties of the beech wood (Fagus orientalis Lipsky.) naturally growing in the Andırın region (the East Mediterranean region), and compare these properties with those of beech wood growing in the Black Sea region. The physical properties investigated were air and oven-dry density, basic density value, tangential, radial, longitudinal and volumetric shrinkage and swelling. The tests of the physical properties were performed on small clean specimens of beech wood selected from the most suitable stands by following the conventional methods. The average air-dry density, oven-dry density, basic density value, volumetric …
Effect Of Glucosidases Enzyme Treatment On Aroma Compounds Of The White Muscat Of Alexandria And Emir Wines, Turgut Cabaroğlu, Ahmet Canbaş
Effect Of Glucosidases Enzyme Treatment On Aroma Compounds Of The White Muscat Of Alexandria And Emir Wines, Turgut Cabaroğlu, Ahmet Canbaş
Turkish Journal of Agriculture and Forestry
The effect of an exogenous commercial enzyme with glycosidase activities on free and glycosidically bound aroma compounds of the white wines obtained from muscat of Alexandria and Emir cultivars was investigated. The fermenting must was divided into two equal parts towards the end of the fermentation and 40 mg/l of enzyme was added to one part. The aroma compounds of the wines were extracted with Amberlite XAD-2 resin and were identified by gas chromatography-mass spectrometry. Their concentrations were determined by gas chromatography. As a result of the enzyme treatment, the concentration of free aroma compounds (terpenes, volatile phenols, C-13 norisoprenoids …
Aplikasi Wayarles Menggunakan Telefon Bimbit Dengan-Wap, Wan Osman Wan Maria
Aplikasi Wayarles Menggunakan Telefon Bimbit Dengan-Wap, Wan Osman Wan Maria
Student Works (2000-2009)
“Wireless Site Solution using WAP-enabled Mobile Phone” is an application developed based on WAP technology. It makes use of the N-tier Client/Server Architecture to provide users especially those who are still new in this technology. With wireless access to manage their daily task and get latest information as well. The main purpose of this project is to provide an alternative for users in managing their daily tasks in some simple clicks and also to allow users to access information in a very interesting way. There are two major modules in this application which are the user module and administrator module. …
Sistem Pembelian Kereta Baru Dalam Talian, Jaafar Muhammad Hanif
Sistem Pembelian Kereta Baru Dalam Talian, Jaafar Muhammad Hanif
Student Works (2000-2009)
Latihan ilmiah merupakan salah satu kursus wajib yang mesti diambil bagi memenuhi keperluan pengijazahan dalam pengajian Sarjana Muda Sains Komputer Universiti Malaya. Bagi memenuhi tujuan ini, saya telah memilih tajuk sistem pembelian kereta baru sebagai tajuk tesis dan penyelia ialah En. Mustaffa Kamal b. Mohd Nor. Dalam membangunakan sesuatu sistem, cadangan projek diperlukan bagi menjelaskan kefahaman pelajar terhadap sistem yang akan dibangunkan. Dalam cadangan projek ini saya akan menerangkan secara ringkas tentang sistem yang akan dibangunkan, bagaimana sistem akan dibangunkan, objektif pembangunan sistem, apakah kelemahan dan kebaikan sistem yang akan dibangunkan, siapakah pengguna-pengguna sistem, peralatan-peralatan yang digunakan dalam pembangunan sistem, …
Web Site And Information System For Idaman Realty, Gopal Krishnan Lavania
Web Site And Information System For Idaman Realty, Gopal Krishnan Lavania
Student Works (2000-2009)
I have chosen this topic of designing a web site for a real estate company as my project. This system which will be developed will give idaman realty an opportunity to have their own web site, whereby they can conduct business and attract customer to their company. This project is done in 2 part, WXET 3181 and WXET 3182. WXET 3181 will involve the system's proposal and documentation. While WXET 3182 will involve designing, implementing, testing and evaluating the system. This project is done as part of fulfilling the requirements for a Bachelor's Degree in Information Technology. I hope this …