Digital Commons Network^™

Effect Of A Single Amino Acid Change In Mhc Class I Molecules On The Rate Of Progression To Aids, Xiaojiang Gao, George W. Nelson, Peter Karacki, Maureen P. Martin, John Phair, Richard A. Kaslow, James J. Goedert, Susan Buchbinder, Keith Hoots, David Vlahov, Stephen J. O'Brien, Mary Carrington

Biology Faculty Articles

Background From studies of genetic polymorphisms and the rate of progression from human immunodeficiency virus type 1 (HIV-1) infection to the acquired immunodeficiency syndrome (AIDS), it appears that the strongest susceptibility is conferred by the major-histocompatibility-complex (MHC) class I type HLA-B*35,Cw*04 allele. However, cytotoxic T-lymphocyte responses have been observed against HIV-1 epitopes presented by HLA-B*3501, the most common HLA-B*35 subtype. We examined subtypes of HLA-B*35 in five cohorts and analyzed the relation of structural differences between HLA-B*35 subtypes to the risk of progression to AIDS. Methods Genotyping of HLA class I loci was performed for 850 patients who seroconverted and …

May 21, 2001 Reporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.

Phytochemistry And Chemosystematics Of Artemisia Arctica In Alaska, Chance W. Riggins

Chemistry and Biochemistry

Artemisia L. (Asteraceae - Anthemideae) is a large and taxonomically complex genus occurring widely throughout the northern hemisphere. Chemical investigations in this genus have mainly been stimulated by the economic and/or medicinal importance of many of its members. This chemical knowledge has also provided useful criteria for resolving systematic uncertainties within the genus. Alaskan Artemisia species are little known chemically despite their historic and contemporary medicinal use. Therefore, an investigation of the chemistry of Alaskan Artemisia arctica was initiated with the dual purpose of searching for structurally novel and/or biologically active compounds and contributing additional criteria for systematic studies of …

May 14, 2001 Reporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.

Ke Alaka'i, Vol. 65, No. 18 (2001-05-09), Brigham Young University Hawaii

Ke Alaka'i

No abstract provided.

The Impact Of Hiv/Aids On Food Production (Focusing Mainly On Rural Farms In Sub-Saharan Africa) And The Effects On The Supply, Demand, And Wages Of Farm Labor, Muhammad Zubair Qamar

Theses & Honors Papers

Utilizing empirical data from studies conducted mainly by international organizations, such as the UNAIDS and the Food and Agriculture Organization , the thesis aims to strengthen the hypothesis that the higher the frequency of HIVIAIDS, mainly in rural African farm communities, the higher the impact there is on food production. Moreover, the supply, demand, and wages of farm labor are also affected by HIV/AIDS. To give a background of the conditions of disease, the first part of the thesis gives an overview of the history of disease. The history and possible origins of HIV/AIDS are delved into, after …

May 7, 2001 Reporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.

The Effects Of Institutionalization On Romanian Children When Adopted Into Families In The United States, Dawn M. Roy

Theses and Dissertations

This study attempts to research the dynamic factors involved in the assessment of children placed in adoptive homes in the United States who were taken from large institutional orphanages in Romania. This paper will discuss various aspects of problems that were encountered by children who lack the stimulation, stability and love that are crucial during the early years of development. It also endeavors to provide interventions that will enable these children to progress along more developmentally appropriate guidelines.

This project utilized a single subject design. The analysis was descriptive in nature. It measured the improvement of mean utterance length. The …

Bjc Today

BJC Today

No abstract provided.

Washington University Record, May 4, 2001

Washington University Record

No abstract provided.

Pacific Sponges May Hold Key To Treating World's Deadliest Diseases, Mitchell Diggs

University of Mississippi News

UNIVERSITY, Miss -- Many people who visit the South Pacific bring back a few shells or other trinkets, but Dr. Mark Hamann doesn't stop there. Returning from a two-week trip to Indonesia and Singapore recently, he brought home nearly 100 pounds of colorful sea sponges.

Arbiter, May 2, Students Of Boise State University

Student Newspapers

No abstract provided.

Growth And Human Development: Comparative Latin American Experience, Gustav Ranis, Frances Stewart

Discussion Papers

No abstract provided.

Mortality In The North Dublin Union During The Great Famine, Timothy W. Guinnane, Cormac Ó Gráda

Discussion Papers

No abstract provided.

Progress Notes, Lehigh Valley Health Network

Progress Notes

No abstract provided.

Hepp News, Vol. 4 No. 5, Hiv & Hepatitis Education Prison Project

Infectious Diseases in Corrections Report (IDCR)

No abstract provided.

Icam-1 Transmembrane Signaling: Involvement Of Taxreb107 In Icam-1-Mediated Signal Transduction, Brian Lee

Yale Medicine Thesis Digital Library

The role of membrane ICAM-1 in intercellular adhesion, through interaction with the leukocyte beta2 integrin receptors LFA-1 and Mac-1, is well established. However, until recently, ICAM-1 was widely regarded as being simply an "anchor" molecule, promoting, for example, firm adhesion of lymphocytes to vascular endothelial cells. The demonstration that ICAM-1 is connected to the actin-based cytoskeleton through interactions with subcortical actin-binding proteins, such as alpha-actinin, enhanced this concept. However, ICAM-1 has been increasingly shown to have signaling properties of its own. Engagement of ICAM-1 extracellularly, either through its natural counter-receptors, LFA-1/Mac-1, or through antibody mediated clustering, can produce numerous changes …

Same Planet - New World?: A Chronicle Of The American Century, Don P. Diffine Ph.D.

Belden Center Books

This book is a normative audit of the past hundred years in the U.S. economy. As we tiptoe into the new millennium, we are the oldest living republic. However, let's remember that our Constitution doesn't guarantee us a good life, prosperous life, a happy life, or even a long life. It only offers the protection of life. We make of our lives what we will. We should bet on the long run future success of American capitalism. If we don't have a future, nobody does.

Greenhouse Gas Emissions Inventory 1990-2000 Full Report, Adam Wilson

The Sustainability Institute Publications

No abstract provided.

Relationship Between Cag Repeats Of The N Terminal Region Of The Androgen Receptor And Body Shape, Michael John Wen

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Androgen receptor (AR) gene CAG polymorphisms may be associated with body shape, and are associated with certain breast and prostate cancers. In addition, body shape is associated with risk for a variety of diseases, including heart disease, diabetes, and certain forms of cancer. The CAG repeat in exon l of the AR gene was quantified using Perkin Elmer Applied Biosystems GeneScan analysis software in 96 and 59 healthy Caucasian men and women, respectively, who were over the age of 50 years. All participants had body measurements taken and donated a blood sample. Waist measurements included circumferences at the 1) umbilicus …

Morphine Enhances The Permeability Across Vascular Endothelial Cell Barriers, Jenine Anday

Seton Hall University Dissertations and Theses (ETDs)

Using three types of in vitro endothelial cell barrier models, we investigated the direct effects and mechanisms of morphine on vascular permeability. Our current studies illustrate LPS induces permeability across these VEC barriers, and is significantly enhanced when co-treated with morphine, displayed using the [ 14 CJ-inulin paracellular marker. Incubation with morphine alone induces permeability in a concentration­ depeodent manner, and is not blocked by the addition of naloxone. Morphine enhances the detrimental effects of LPS on cell viability and alone also decreases endothelial cell viability, concentration-dependently, which is also not affected by naloxone, as demonstrated by the trypan blue …

Legal Issues In Hiv/Aids Prevention And Treatment In The Russian Federation – Summary And Conclusions Of The Boston University Hiv/Aids Project, Wendy K. Mariner

Faculty Scholarship

The Russia Federation faces an urgent need to control the spread of HIV. Although infection has been concentrated primarily among high risk groups so far, the risk that it will spread rapidly throughout the general population is growing daily. Controlling the HIV epidemic requires leadership and strategies that are somewhat different from traditional infectious disease control models because there is no vaccine yet available to prevent disease and people spread infection by engaging in activities that are hidden from public view and not susceptible to simple prohibitions.

Boston University conducted several studies as part of USAID’s HIV/AIDS Strategy to assist …

Clumping Factor A Mediates Binding Of Staphylococcus Aureus To Human Platelets, Ian R. Siboo, Ambrose L. Cheung, Arnold S. Bayer, Paul M. Sullam

Dartmouth Scholarship

The direct binding of bacteria to platelets may be an important virulence mechanism in the pathogenesis of infective endocarditis. We have previously described Staphylococcus aureus strain PS12, a Tn551-derived mutant of strain ISP479, with reduced ability to bind human platelets in vitro. When tested in an animal model of endocarditis, the PS12 strain was less virulent than its parental strain, as measured by bacterial densities in endocardial vegetations and incidence of systemic embolization. We have now characterized the gene disrupted in PS12 and its function in platelet binding. DNA sequencing, Southern blotting, and PCR analysis indicate that PS12 contained two …

Decomposition Of Relations: A New Approach To Constructive Induction In Machine Learning And Data Mining -- An Overview, Marek Perkowski, Stanislaw Grygiel

Electrical and Computer Engineering Faculty Publications and Presentations

This is a review paper that presents work done at Portland State University and associated groups in years 1989 - 2001 in the area of functional decomposition of multivalued functions and relations, as well as some applications of these methods.

April 30, 2001 Reporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.

Washington University Record, April 27, 2001

Washington University Record

No abstract provided.

The Pan American (2001-04-26), Matt Lynch

UTPA Archives - The Pan American Newspaper

49th Year, No. 49

Persistent Fontanelles In Rodent Skulls, Scott Lyell Gardner, Sydney Anderson

Harold W. Manter Laboratory of Parasitology: Faculty Publications

Persistent fenestrae occur between frontal or parietal bones in skulls of various rodents, especially species of Andinomys and Ctenomys. The frequency of occurrence and the shape and position of the fenestrae may vary with age or among individuals, populations, and species. Different families and species from both high and low elevations exhibit fenestrae. They have arisen in several different evolutionary lineages. Genetic factors contribute, but no clear functional significance of the fenestrae has been established.

April 26, 2001, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.

Banner News, Jack Wilson, Katie Prescott, Mary Beth Hanlin, Matthew Rinker, Ted Herrick, Aaron Ladage, Karol King, Michele Thamke, Samantha Schmidt, Darren Johnson, Scott Anderson

Banner News

No abstract provided.