Digital Commons Network^™

Α-Amino-Β-Sulphone Hydroxamates As Potent Mmp-13 Inhibitors That Spare Mmp-1, Daniel P. Becker Ph.D., Thomas E. Barta, Louis Bedell, Gary Decrescenzo, John Freskos, Daniel P. Getman, Susan L. Hockerman, Madeleine Li, Pramod Mehta, Brent Mischke, Grace E. Munie, Craig Swearingen, Clara I. Villamil

Chemistry: Faculty Publications and Other Works

A series of α-amino-β-sulphone hydroxamates was prepared and evaluated for potency versus MMP-13 and selectivity versus MMP-1. Various substituents were employed on the α-amino group (P1 position), as well as different groups attached to the sulphone group extending into P1′. Low nanomolar potency was obtained for MMP-13 with selectivity versus MMP-1 of >1000× for a number of analogues.

α-Amino-β-sulphone hydroxamates were prepared, which are potent MMP-13 inhibitors with selectivity versus MMP-1 of >1000× for a number of analogues. Selected compounds exhibited oral bioavailability.

In Hoc Signo Vinces: Religious Symbolism In The Balkan Wars 1991-1995, Mitja Velikonja

Occasional Papers on Religion in Eastern Europe

No abstract provided.

Richmond Law Magazine: Fall 2001

Richmond Law Magazine

Features:

Bench Marks

"He Really Taught Advocacy"

Learning Opportunities 2001/2002, Illinois Mathematics And Science Academy

Course Catalogs

Students must enroll in a "core" mathematics course each semester, advancing to the highest level possible during their six semesters at IMSA.

The Externality Of Victim Care, Alan J. Meese

Faculty Publications

No abstract provided.

The Advocate (Fall 2001), Lewis & Clark Law School

The Advocate

No abstract provided.

Drama Beat (Fall 2001) | Newsletter, Jacksonville State University

Department of Theatre & Film Performance Archive

15-19 November 2001; "Rumors." This item is contained within the Theatre & Film Production Archive.

The Making Of George Sessions Perry, Garna L. Christian

East Texas Historical Journal

No abstract provided.

Culture In Cowtown: The Amon Carter Musuem, Bart C. Pointer

East Texas Historical Journal

No abstract provided.

Jacob & Joseph, Lawrence Raful

Scholarly Works

No abstract provided.

Book Review: Not Just Women's Work: Relocating Gender In Studies Of Labour Regulation - Reviews Of: Temporary Work: The Gendered Rise Of A Precarious Employment Relationship, By Leah F. Vosko; The Global Construction Of Gender: Home Based Work In The Political Economy Of The 20th Century, By Elisabeth Prugl, Ruth Buchanan

Osgoode Hall Law Journal

No abstract provided.

Alcalá View 2001 18.02, University Of San Diego Publications And Human Resources Offices

Alcalá View (1985-2006)

Survey Helps Plan Next Year's Bash; The Park Ranger Mornings with Otis; For Your Benefit…; SEA Snippets; It's A Date!; In the Spotlight Extraordinary People, Extraordinary Times; Ask H.R.; Milestones; A Note of Thanks; Faculty and Curriculum Development Programs; USD Team Had a lot of Heart; Classifieds

Vaccination Program For Beef Calves (2001 - Clell Bagley), Clell Bagley

All Current Publications

Vaccines are an important tool to use in herd health programs for the protection of animal health. However, vaccines do not prevent all disease by themselves, and should be used in conjunction with good management practices. The timing of vaccination and selection of product are important considerations.

The Origins And Constitutionality Of State Unit Voting In The Electoral College, Matthew J. Festa

Vanderbilt Law Review

On November 1, 2000, a Joint Resolution was introduced in Congress proposing a constitutional amendment to change the Article II system of electing the President and Vice President' by abolishing the Electoral College. Acknowledging the fact that "there have been more congressionally proposed constitutional amendments on this subject than any other," the sponsoring Senator noted that the issue "could become supremely important in a few days," because "we have the possibility that the winning candidate for President might not win the popular vote in our country.' One prominent legal scholar has described the mere possibility of such an event as …

2001 October, Office Of Communications & Marketing, Morehead State University.

Morehead State Press Release Archive, 1961 to the Present

Morehead State University press releases for October of 2001.

Let's Cross Platforms, Miyoung Yoon

Theses

Different platforms and browsers render text and images differently. Therefore, web designers should know how to deal with these types of media. Many web designers use the Macintosh, and the majority of the users are on the PC. This thesis project examines the visual elements of web design consisting of fonts, colors, and graphics and how they change between the PC and Mac. The two major browsers used by people to surf the web are Internet Explorer and Netscape Navigator and they also cause problems with consistency. Resolution differences cause font problems. Knowing the default system resolution to specify with …

Illinois State Magazine, Fall 2001, University Marketing And Communications

Illinois State Magazine (1999-present)

Alumni magazine for Illinois State University

Report, Florida Ornithological Society Conservation Committee, Red-Cockaded Woodpecker Proposal, Circa October 2001, Florida Ornithological Society. Conservation Committee

Florida Ornithological Society - Records - Full Collection

A report from the Florida Ornithological Society's Conservation Committee about the status of the Red-cockaded woodpecker.

Statement, Fall 2001, Office Of Alumni Relations. Morehead State University

Morehead State Alumni Association Publications

Statement Magazine of Morehead State University from Fall of 2001.

The Legal Subject In Exile, Kathryn Abrams

Duke Law Journal

No abstract provided.

Federalism And The Double Standard Of Judicial Review, Lynn A. Baker, Ernest A. Young

Duke Law Journal

From 1937 to 1995, federalism was part of a “Constitution in exile.” Except for the brief interlude of the National League of Cities doctrine2—which, like Napoleon’s ill-fated return from Elba, met with crushing defeat3—the post–New Deal Supreme Court has been almost completely unwilling to enforce constitutional limits on national power vis-à-vis the states. The reason, by all accounts, has much to do with federalism’s historic link to other aspects of our expatriate constitution—e.g., economic substantive due process, legislative nondelegation— which were banished for their collusion against the New Deal.

Charles Hartshorne's Letters To A Young Philosopher: 1979-1995, Donald W. Viney

Faculty Submissions

This book brings together all of the letters exchanged between Charles Hartshorne and Donald W. Viney between 1979 and 1995

The Standardized Fish Bioassay Procedure For Detecting And Culturing Actively Toxic Pfiesteria, Used By Two Reference Laboratories For Atlantic And Gulf Coast States, Joann M. Burkholder, Harold G. Marshall, David W. Seaborn, Nora J. Deamer-Melia

Biological Sciences Faculty Publications

In the absence of purified standards of toxins from Pfiesteria species, appropriately conducted fish bioassays are the "gold standard" that must be used to detect toxic strains of Pfiesteria slop. from natural estuarine water or sediment samples and to culture actively toxic Pfiesteria. In this article, we describe the standardized steps of our fish bioassay as an abbreviated term for a procedure that includes two sets of trials with fish, following the Henle-Koch postulates modified for toxic rather than infectious agents. This procedure was developed in 1991, and has been refined over more than 12 years of experience in …

The Emblem And Motto Of The Congregation Of The Mission, John E. Rybolt C.M., Ph.D.

Vincentian Studies

The emblem of Jesus standing on a globe with his arms stretched downward and the biblical citation Evangelizare pauperibus misit me are the Congregation’s most familiar emblem and motto. They have been known since the time of Vincent de Paul, but have only been used together since the mid-nineteenth century. Their origins and antecedents, along with other emblems and mottos that have been employed, are discussed. Their uses and theological meaning are explained. Twenty-six images are included.

Mandatory Minimum Sentences Coupled With Multi-Facet Interventions: An Effective Response To Domestic Violence, Angela M. Killian

University of the District of Columbia Law Review

No abstract provided.

Ensemble Concerts: Wind Symphony, September 30, 2001, Stephen K. Steele

School of Music Programs

Bone Student Center Ballroom
Sunday Afternoon
September 30, 2001
3:00 p.m.

The First Witness: Amos Root At Huffman Prairie, James Tobin

Following in the Footsteps of the Wright Brothers: Their Sites and Stories

The article, The First Witness: Amos Root at Huffman Prairie, was presented by James Tobin at the Following the Footsteps of the Wright Brothers: Their Sites and Stories Symposium at Wright State University, September 28, 2001. The article discusses how Amos Root witnessed the Wright Brothers flying at Huffman Prairie and his general interest in their inventions. Tobin also discusses the life of Amos Root and how he gained fame through beekeeping.

Over A Herd Of Cattle: The Wright Brothers And The Pursuit Of Flight At Huffman Prairie Flying Field, Elizabeth Fraterrigo

Following in the Footsteps of the Wright Brothers: Their Sites and Stories

The article, 'Over a Herd of Cattle': The Wright Brothers and the Pursuit of Flight at Huffman Prairie Flying Field, by Elizabeth Fraterrigo discusses the role that Huffman Prairie played in the events of the Wright Brothers early attempts at perfecting flight. Fraterrigo explains the use of the field and difficulties faced by the Wright Brothers and the advances that they made due to the flights at Huffman Prairie. The article was presented at the Following the Footsteps of the Wright Brothers: Their Sites and Stories Symposium at Wright State University, September 28, 2001.

Fieldnotes On Interview With Jeanette Corine May, Wife Of Late Walter L. Mayo, Peg Tazewell

Interviews

The interview is conducted at Mayo's house and Jeanette talks about Mayo. The interviewer also takes note of the diferent themes present in Mayo's artwork.

The Good 5 Cent Cigar (09/28/2001), University Of Rhode Island

The Good 5 Cent Cigar (Student Newspaper Archives)

This is a digitized, downloadable version of the University of Rhode Island school newspaper.