Digital Commons Network^™

Identification Of Potential Molecular Biomarkers Of Cadmium Induced Stress In C̲Hironomus Tentans ̲, David Hunter Dyer

Dissertations and Theses @ UNI

The objective of this research was to identify potential molecular biomarkers by looking for differences in the mRNA expression patterns between cadmium exposed and non-exposed freshwater aquatic invertebrate larvae. In the future, genes that indicate sublethal damage to a population at risk could be used to monitor the degradation or regeneration of an ecosystem. For this study, laboratory reared Chironomus tentans were placed in a sublethal concentration of cadmium treated water and the genes turned on in response to the cadmium were isolated from a cDNA subtract library. Six genes were identified and two potential biomarkers of environmental stress, ferritin …

Effects Of Electrical Stimulation On Wound Closure In Mice With Experimental Diabetes Mellitus, Habiba A. Thawer, Pamela E. Houghton, Luther Kloth, Anna Butryn

Physical Therapy Faculty Research and Publications

The purpose of the present study was to examine the effect of electrical stimulation (ES) on the closure of full-thickness excisional wounds in mice with type-1 experimental diabetes mellitus (DM). Alloxon monohydrate (100mg/kg) was used to induce experimental DM in mole CD-1 mice (n = 88). Full-thickness skin excisions (1cm²) in diabetic (urine glucose > 0) and non-diabetic (urine glucose = 0) mice were administered 1, 3, or 5 treatments of ES (200μs, 200 Hz) for 15 minutes, at 0 (sham), 5, 10, or 12.5 volts. Alloxon injection resulted in a positive urine glucose test in 48 mice yielding …

Detection And Modeling Of Radiation Induced Effects In Tissues By Dielectric Spectroscopy, Dorin A. Todor

Physics Theses & Dissertations

The work presented here is applied physics research in the field of radiation treatment. We address the development of a new and innovative method, in vivo and possibly non-invasive, for tumor and healthy tissues control during and after the radiation treatment. The radiation treatment is delivered in an almost standardized manner for particular classes of tumors. The large variance in the individual radio sensitivity of healthy tissues and tumors often leads to local recurrence of neoplastic growth and/or distant metastatic disease which often remains untreated. The method is based on the measurement and analysis of electrical impedance data in …

Transcriptional Regulation Of Chicken Apolipoprotein A-I Gene Expression, Wen Lin Kumfert

Theses and Dissertations in Biomedical Sciences

Deregulation of a set of critical cellular genes has long been speculated as a cause of the oncogenic transformation induced by v-Jun oncoprotein. In the past several years, extensive efforts have been made to identify such genes. Several target genes have been identified that are specifically associated with the v-Jun induced transformation phenotype in chicken embryo fibroblasts (CEF).

We have undertaken the objective to identify and characterize the genes that become deregulated in response to, or as a consequence of, Jun-induced transformation. By exploiting the difference in oncogenic potential between v-Jun and c-Jun in CEF, the chicken apolipoprotein A-I (apoA-I) …

Human Gonadotropin-Releasing Hormone (Hgnrh) Gene Expression And Hormone Regulation In Human Placental Jeg-3 Cells, Heming Zheng

Theses and Dissertations in Biomedical Sciences

Using the human placental choriocarcinoma JEG-3 cell line as an in vitro human placental model, I studied the mechanisms of the tissue-specific expression and steroid hormone regulation of the hGnRH gene in the human placenta. The results showed that all of the previously identified four elements are required for the full activity of the hGnRH upstream promoter in JEG-3 cells, while the element 4 (FP4, −987/−968) is the most important. Studies performed with 5′ end deletion of this region confirmed these observations. Further, supershift assay using Oct-1 antibody demonstrated the involvement of Oct-1 in the FP4 DNA-protein interaction in JEG-3 …

Madaba Plains Project Tall Hisban, 1998, Øystein Sakala Labianca, Paul J. Ray Jr., Bethany Walker

Andrews University Seminary Studies (AUSS)

No abstract provided.

Protein Polymorphism In Two Populations Of The Brown Ear Tick, Rhipicephalus Appendiculatus Neumann (Acari: Ixodidae), F. N. Baliraine, E. O. Osir, S. B. Obuya', F. J. Mulaa

All Peer-Reviewed Publications

Two-dimensional gel electrophoresis was used to compare the protein profiles of two geographically isolated populations of the tick Rliipiccplmlus appcndiciilalus Neumann (Acnri: Ixodidne) in Kenya. Most of the protein spots were common to both populations, but a number were specific to each population. Since proteins are encoded by genes, the presence of populationspecific proteins suggests that there.may be genetic differences between the two populations. It is proposed that some of these population-specific proteins might be related to the differences in susceptibility of the ticks to Thcikria pawn infection. ©2000ICIPE.

Snow!, Enok Mortensen

The Bridge

The winter had been unusually mild. For many years, people had never seen anything like it. The old folks even thought that there was something wrong with such unusual weather. Coal dealers cursed and knocked on their barometers, but the temperature held above freezing and well into December no snow fell. In Grant Park, which Chicago had wrested from Lake Michigan, a faint sun kissed the faded grey lawn and warmed it enough so that fat wealthy women took out their yappy lap dogs. In long uneven rows the homeless lay in rags and stole a belated sleep well into …

Madaba Plains Project 4: The 1992 Season At Tall Al-'Umayri And Subsequent Studies, Larry G. Herr Editor, Douglas R. Clark Editor, Lawrence T. Geraty Editor, Randall W. Younker Editor, Oystein Sakara Labianca Editor

All Books

"The fourth volume of the Madaba Plains Project series entitled Madaba Plains Project 'Umayri 4: The 1992 Season at Tall al-'Umayri and Subsequent Studies. ... This volume is dedicated to His Royal Highness Prince El-Hassan bin Talal of the Hashemite Kingdom of Jordan whose long-standing support of archaeology in Jordan has earned both admiration and deep respect. The field reports examine the Iron II/Persian Administrative Complex (Ch. 3), Western Defense System (Ch. 4), the Lower Southern Terrace (Ch. 5) and the Eastern Shelf (Ch. 6). These include stratigraphic information, section drawings and pottery plates. Detailed photographs and line drawings make …

Creation, Life, And Hope: Essays In Honor Of Jacques B. Doukhan, Jiri Moskala

All Books

No abstract provided.