Digital Commons Network^™

Human Immunodeficiency Virus Neurotropism: An Analysis Of Viral Replication And Cytopathicity For Divergent Strains In Monocytes And Microglia, Anuja Ghorpade, Adeline Nukuna, Myhanh Che, Sheryl Haggerty, Yuri Persidsky, Eboni Carter, Leeroy Carhart, Laura Shafer, Howard Gendelman

Nebraska Center for Virology: Faculty Publications

Productive replication of human immunodeficiency virus type 1 (HIV-1) in brain macrophages and microglia is a critical component of viral neuropathogenesis. However, how virus-macrophage interactions lead to neurological disease remains incompletely understood. Possibly, a differential ability of virus to replicate in brain tissue macrophages versus macrophages in other tissues underlies HIV-1 neurovirulence. To these ends, we established systems for the isolation and propagation of pure populations of human microglia and then analyzed the viral life cycles of divergent HIV-1 strains in these cells and in cultured monocytes by using identical viral inocula and indicator systems. The HIV-1 isolates included those …

Vital Signs, Spring 1998, Boonshoft School Of Medicine

Vital Signs

A twenty four page newsletter created by the Boonshoft School of Medicine to document the current affairs of the school. This issue includes a variety of feature articles, alumni profiles, class notes, and more.

Wsu Research News, Spring 1998, Office Of Research And Sponsored Programs, Wright State University

WSU Research News

A ten page newsletter of the WSU Research News. The WSU Research News was published monthly beginning in June of 1968 and issued by the Office of Research Development. This newsletter was created to provide information to the WSU faculty about the availability of outside funds for research and educational programs, new developments that may affect availability of funds, and general information on research and educational activities at Wright State University.

Adaptive Strategies In The Indian Pharmaceutical Industry, Rishikesha T Krishnan, T R Madanmohan

Working Papers

How do firms react when an industry faces increased competitive pressures due to trade liberalisation? Firms are believed to bring about changes in their technology, marketing and organisation by reorganisation and redeployment of resources, often through exit process (Buffie and Spiller 1986, Ross 1988). Pavitt's (1990) analysis of technological opportunity and innovations, Ettlie and Bridges's (1982) analysis of environmental uncertainty and its impact on technological performance seem to support this. Many research results have observed that environment can affect firms' strategies (Jemison 1981, McArthur and Nystrom 1991), and under conditions of increased uncertainty firms employ innovative strategies (Paine and Anderson …

The Benefits Of Low-Earth Orbiting Satellite Technology For The International Community: Can The Potential Be Realized, Mark Nogueira

Indiana Journal of Global Legal Studies

No abstract provided.

Digest Of The Philadelphia College Of Osteopathic Medicine (Spring 1998), Philadelphia College Of Osteopathic Medicine

Digest

The Spring 1998 issue of the Digest of the Philadelphia College of Osteopathic Medicine includes the following articles:

• Opening Remarks
• PCOM Updates
• Our Centennial
• Planting the Seeds for Better Physician Communication
• Library Steps into 21st Century
• Convention Highlights
• Uncle Manny Leaves a Legacy
• Mission Milestones
• Profiles
• Lights, Camera, Action
• Class Notes
• Just Published
• In Memoriam
• Coming Events

1998 Tenth Annual Imsa Presentation Day, Illinois Mathematics And Science Academy

IMSAloquium Event Booklets

"Research is the fundamental activity of science. By engaging in authentic research, one can better appreciate the concepts and theories underlying science and discover new pathways for improving the human condition."

Globalizing The Environment, David A. Wirth

William & Mary Environmental Law and Policy Review

No abstract provided.

An Analysis Of Fecal Coliform Bacteria As A Water Quality Indicator, Janet Heyl Vail

Dissertations

The focus of this study is to assess the efficacy of fecal coliform bacteria as a microbiological water quality indicator. The scientific and educational context of fecal coliform bacteria is explored through analysis of large sets of water quality data, focused field monitoring projects, and review of commonly used resources for school-based and volunteer water-related studies. Analyzed data sets include long term sampling (10 years), multiple sites, daily samples, storm event samples, and other parameters monitored in parallel with bacteria. Special attention is given to data sets from Kent County, Michigan. A background reference site in Michigan unimpacted by humans …

The Ethics Of Contact Tracing Programs And Their Implications For Women, Nancy E. Kass, Andrea Carlson Gielen

Duke Journal of Gender Law & Policy

No abstract provided.

Piercing The Veil Of Secrecy In Hiv/Aids And Other Sexually Transmitted Diseases: Theories Of Privacy And Disclosure In Partner Notification, Lawrence O. Gostin, James G. Hodge Jr.

Duke Journal of Gender Law & Policy

No abstract provided.

A Waiting Room Of Their Own: The Family Care Network As A Model For Providing Gender-Specific Legal Services To Women With Hiv, Jeffrey Selbin, Mark Del Monte

Duke Journal of Gender Law & Policy

No abstract provided.

Hiv, Women, And Access To Clinical Trials: Tort Liability And Lessons From Des, Anna C. Mastroianni

Duke Journal of Gender Law & Policy

No abstract provided.

Human Immunodeficiency Virus Neurotropism: An Analysis Of Viral Replication And Cytopathicity For Divergent Strains In Monocytes And Microglia, Anuja Ghorpade, Adeline Nukuna, Myhanh Che, Sherryl Haggerty, Yuri Persidsky, Eboni Carter, Leeroy Carhart, Laura Shafer, Howard Gendelman

Nebraska Center for Virology: Faculty Publications

Productive replication of human immunodeficiency virus type 1 (HIV-1) in brain macrophages and microglia is a critical component of viral neuropathogenesis. However, how virus-macrophage interactions lead to neurological disease remains incompletely understood. Possibly, a differential ability of virus to replicate in brain tissue macrophages versus macrophages in other tissues underlies HIV-1 neurovirulence. To these ends, we established systems for the isolation and propagation of pure populations of human microglia and then analyzed the viral life cycles of divergent HIV-1 strains in these cells and in cultured monocytes by using identical viral inocula and indicator systems. The HIV-1 isolates included those …

Species Of Myxobolus (Myxozoa) From The Bulbus Arteriosus Of Centrarchid Fishes In North America, With A Description Of Two New Species, David K. Cone, Robin M. Overstreet

Harold W. Manter Laboratory of Parasitology: Faculty Publications

Three species of Myxobolus (Myxozoa, Myxosporea) occur in heart tissue of centrarchids. Myxobolus paralintoni Li and Desser, 1985 from Lepomis gibbosus in Algonquin Park and in Lake Erie, Ontario, has subcircular spores (in plane of spore length) in frontal view (11-13 μm long, 9-10 μm wide, and 5 μm thick) with a width-to-length ratio of 1:1.2. Myxobolus jollimorei n. sp. from Lepomis macrochirus in Lake Erie and in the Pascagoula River System, Mississippi, has subcircular spores (in plane of spore width) in frontal view (10.0-11.5 μm long, 12.0-14.5 μm wide, and 6.5-8.0 μm thick) with a width-to-length ratio of 1:0.8. …

Occurrence And Morphological Comparisons Of Campula Oblonga (Digenea: Campulidae), Including A Report From An Atypical Host, The Thresher Shark, Alopias Vulpinus [Research Notes], Ann M. Adams, Eric P. Hoberg, D. F. Mcalpine, S. L. Clayden

Harold W. Manter Laboratory of Parasitology: Faculty Publications

New host records for Campula oblonga Cobbold, 1858 from the common dolphin, Delphinus delphis L., and from the thresher shark, Alopias vulpinus (Bonnaterre), are reported herein. Campulids have not been reported previously from a host that was not a marine mammal. The excellent condition and small size of the gravid specimen and the diet and natural history of the thresher shark lead us to conclude that the digene was acquired from the consumption of infected fish. Specimens of C. oblonga from these two hosts and from harbor porpoises, Phocoena phocoena (L.), and from Dall's porpoises, Phocoenoides dalli (True), are compared, …

The Chironian Vol. 115 Spring 1998, New York Medical College

The Chironian

No abstract provided.

Antigen-Specific Cd8+ T Cells Protect Against Lethal Toxoplasmosis In Mice Infected With Neospora Caninum, Lloyd H. Kasper, Imtiaz A. Khan

Dartmouth Scholarship

Neospora caninum is a coccidial protozoan parasite that appears morphologically indistinguishable from Toxoplasma gondii and that infects a large range of mammals. Both inbred and outbred strains of mice exhibit a high degree of resistance to infection with N. caninum. Three inbred strains of mice (A/J, BALB/c, and C57BL/6) that were infected intraperitoneally with N. caninum were protected against a lethal challenge from T. gondii. Vaccine-induced protection was Neospora dose dependent. A rise in the CD8+ T-cell population in mice that had been vaccinated with N. caninum and challenged with T. gondii was observed. Adoptive transfer of CD8+ T-cell splenocytes …

March 30, 1998 Reporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.

The Opinion Volume 38 Number 13 – March 30, 1998, The Opinion

The Opinion Newspaper (all issues)

The Opinion newspaper issue dated March 30, 1998. Includes SBA election insert.

Bjc Today

BJC Today

No abstract provided.

The Bg News March 25, 1998, Bowling Green State University

BG News (Student Newspaper)

The BGSU campus student newspaper. March 25, 1998. Volume 80-Issue 119.

March 23, 1998 Reporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.

Enhancement Of Atp Levels And Glucose Metabolism During An Infection By Chlamydia: Nmr Studies Of Living Cells, David M. Ojcius, H. Degani, Joel Mispelter, Alice Dautry-Varsat

All Dugoni School of Dentistry Faculty Articles

The Chlamydia species are obligate intracellular bacteria that proliferate only within the infected cell. Since the extracellular bacteria are metabolically inert and there are no cell-free systems for characterizingChlamydia metabolism, we studied metabolic changes related to ATP synthesis and glycolysis in HeLa cells infected withChlamydia psittaci during the course of the 2-day infection cycle using noninvasive 31P and 13C NMR methods. We find that the infection stimulates ATP synthesis in the infected cell, with a peak of ATP levels occurring midway through the infection cycle, when most of the metabolically active bacteria are proliferating. The infection also stimulates synthesis of …

The Colby Echo (1998-03-19), Colby College

The Colby Echo

Published by the students of Colby College since 1877, The Colby Echo is the weekly, editorially independent student-run newspaper of Colby College in Waterville, Maine. Published monthly, 1877-1886; semi-monthly, 1886-1897; and weekly, during the academic year, 1898-present.

The Ucf Report, Vol. 20 No. 16, March 6, 1998, University Of Central Florida

The UCF Report

Storms' lesson: take warnings seriously; Seminary-UCF match made in heaven: Partnership prepares missionaries to teach.

Mimicking 'Molecular Machine' May Be Key To Creating An Effective Vaccine Against Hiv/Aids, University Of Montana--Missoula. Office Of University Relations

University of Montana News Releases, 1928, 1956-present

No abstract provided.

Healthy You, Lehigh Valley Health Network

Healthy You

No abstract provided.

Progress Notes, Lehigh Valley Health Network

Progress Notes

No abstract provided.

The Value Of Preventing Cryptosporidium Contamination, Patricia Kocagil, Nadia Demarteau, Ann Fisher, James S. Shortle

RISK: Health, Safety & Environment (1990-2002)

The authors evaluate the need for preventing illnesses and fatalities caused by Cryptospiridium contamination of water supplies based on the impacts of recent and likely future outbreaks.