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Examining The Association Between History Of Cancer Diagnosis And Food Insecurity Among U.S. Adults: A Cross-Sectional Analysis Of The 2024 Nhis, Jacqueline Faerstain, Megan O'Brien Apr 2026

Examining The Association Between History Of Cancer Diagnosis And Food Insecurity Among U.S. Adults: A Cross-Sectional Analysis Of The 2024 Nhis, Jacqueline Faerstain, Megan O'Brien

GW Research Showcase 2021-2026

No abstract provided.


Enhancing Perinatal Mental Healthcare -- The Usefulness Of A Toolkit For Maternity Care Providers To Address Perinatal Mental Health, Claudia Gomez Apr 2026

Enhancing Perinatal Mental Healthcare -- The Usefulness Of A Toolkit For Maternity Care Providers To Address Perinatal Mental Health, Claudia Gomez

GW Research Showcase 2021-2026

No abstract provided.


Oral Health & Academic Stress: Gendered Differences In Dental Habits During Periods Of High Stress, Aviv Shachi, Patrick G. Corr Apr 2026

Oral Health & Academic Stress: Gendered Differences In Dental Habits During Periods Of High Stress, Aviv Shachi, Patrick G. Corr

GW Research Showcase 2021-2026

No abstract provided.


Targeting The Metabolic-Neurodegenerative Axis: In Silico Repurposing Of Fda-Approved Pleiotropic Metabolic Modulators For Alzheimer's Tau Protein, Maanya Chitrapu, Juhi Vora Apr 2026

Targeting The Metabolic-Neurodegenerative Axis: In Silico Repurposing Of Fda-Approved Pleiotropic Metabolic Modulators For Alzheimer's Tau Protein, Maanya Chitrapu, Juhi Vora

Undergraduate Student Symposium

Extensive research has established a link between insulin deficiency and insulin resistance and Alzheimer's Disease (AD) type-neurodegeneration, coining it "Type 3 Diabetes". While research typically focuses on glucose regulation, the comparative structural efficacy of broader metabolic agents against neuropathology remains distinctively underexplored. This study addresses this gap by performing a novel in silico comparison of three drug classes (Glucose, Lipid, and Cardio-Metabolic regulators) to identify superior scaffolds for obstructing the pathological Tau protein, which plays a major role in causing AD through its hyperphosphorylation. The Tau paired helical filament (PDB ID: 5O3L) was retrieved from the RCSB Protein Data Bank. …


University Oral Hygiene Behaviors Compared To The National Population, Noura Naami, Jordan Monteiro, Trisha Jois Apr 2026

University Oral Hygiene Behaviors Compared To The National Population, Noura Naami, Jordan Monteiro, Trisha Jois

Undergraduate Student Symposium

Maintaining optimal oral health is essential for preventing dental caries, periodontal disease, and systemic complications. However, the combined effects of brushing, flossing, and mouthwash, which are common oral practices, remain incompletely understood. While each practice has been studied individually, there is limited data existing that evaluates how different brands and the frequency of use interact to influence the oral environment. In this study, we use a cohort of 40 university aged individuals to examine oral hygiene behaviors compared to the general U.S. population. In regard to flossing, national data suggests that this behavior is the least consistently utilized method of …


The Effects Of Gender Crime Congruency On Jurors' Decisions And Confidence, Elizabeth Avila Apr 2026

The Effects Of Gender Crime Congruency On Jurors' Decisions And Confidence, Elizabeth Avila

Undergraduate Student Symposium

A basic principle of the U.S. court system is that every individual has the right to a fair and unbiased trial. While this is the ideal, it is not always reality. Jurors come in with their own beliefs and attitudes before the trial starts. These preconceived beliefs can jeopardize the integrity of the trial. An example of these beliefs is gender stereotypes. Gender stereotypes can influence a juror's attitude towards a defendant, to either have a more negative or positive view on whether the defendant's gender matched the nature of their crime. This is called gender crime congruency. In this …


Exercise As An Intervention Against Neuroinflammation During Binge Drinking Withdrawal, Shaina Binu, Ellie Wind, Ariana Hernandez, Iliana Uribe, Victoria Pulido-Correa Apr 2026

Exercise As An Intervention Against Neuroinflammation During Binge Drinking Withdrawal, Shaina Binu, Ellie Wind, Ariana Hernandez, Iliana Uribe, Victoria Pulido-Correa

Undergraduate Student Symposium

Binge drinking, a public health concern in the United States, is associated with negative emotional and cognitive effects during alcohol withdrawal. These effects are believed to result from changes in brain regions involved in stress regulation, emotion, and decision-making, including the prefrontal cortex, amygdala, and hippocampus. Alcohol exposure has been shown to increase neuroinflammation in these regions, which may contribute to anxiety-like behaviors and difficulty regulating emotions during withdrawal. In contrast, aerobic exercise is a promising non-pharmacological intervention that has been shown to reduce anxiety and support brain health. This project investigates how exercise can reduce withdrawal-related anxiety-like behaviors, following …


Proximal Power Gains In Football: Position-Specific Adaptations Revealed Through Compositional Data Analysis, Isabella Estrada Hernandez, Alyana Andal Apr 2026

Proximal Power Gains In Football: Position-Specific Adaptations Revealed Through Compositional Data Analysis, Isabella Estrada Hernandez, Alyana Andal

Undergraduate Student Symposium

Training-induced adaptations in joint power distribution during speed running may enhance performance, but how these changes manifest across different American football position groups remains poorly understood. We investigated the influence of training and player position on joint power composition among players training for the National Football League draft. Forty-eight draft-eligible players performed pre- and post-training camp running trials at 23.4 km/h. We used motion capture software and MATLAB to calculate bilateral peak hip, knee, and ankle joint power. Compositional data analysis (CoDA) was used, in which positive/generated and negative/absorbed power compositions were expressed as isometric log-rations: hip versus knee + …


Baseline Emotional Valence Predicts Subsequent Executive Function Task Performance, Andrea Fajardo Aguilar, Alyssa Harris, Isidora Varas-Sanchez, Julia Ribeiro, Dylan Kuni Apr 2026

Baseline Emotional Valence Predicts Subsequent Executive Function Task Performance, Andrea Fajardo Aguilar, Alyssa Harris, Isidora Varas-Sanchez, Julia Ribeiro, Dylan Kuni

Undergraduate Student Symposium

Executive functioning (EF) supports goal-directed behavior and is influenced by affective state. While prior research has largely focused on the effects of emotional valence during task performance, less is known about the influence of pre-task self-reported valence on subsequent EF performance. Our ongoing study will examine whether self-reported ratings of emotional valence assessed prior to the start of a task will predict performance. Participants will report valence ratings during a resting baseline period before performing two EF tasks: the Vertical Stroop and the Go/No-Go. Performance will be assessed using reaction time and accuracy. Regression analyses will be conducted to …


Assessing Recovery In Collegiate Swimmers Through Wearable Technology, Sara Quintero Apr 2026

Assessing Recovery In Collegiate Swimmers Through Wearable Technology, Sara Quintero

Undergraduate Student Symposium

Collegiate swimmers face extreme physiological demands during high-intensity training phases like "Hell Week," a winter training intensive loading microcycle, that makes recovery monitoring critical for maintaining performance. This study investigated the relationship between sleep quality and recovery markers. Specifically, Heart Rate Variability (HRV) and Resting Heart Rate (RHR), in nine female collegiate swimmers (ages 19-23) across all collegiate years. Participants included sprinters, mid-distance, and distance swimmers, leading to varied total yardage across training groups. Over an eight-day period (seven training days and one rest day), data was collected via screenshots from Garmin (n=4) and WHOOP (n=5) wearable devices. Metrics included …


Group Differences In Conflict Processing Between Bilinguals And Monolinguals, Isidora Varas-Sanchez, Dylan Kuni, Julia Ribeiro, Andrea Fajardo Aguilar, Alyssa Harris Apr 2026

Group Differences In Conflict Processing Between Bilinguals And Monolinguals, Isidora Varas-Sanchez, Dylan Kuni, Julia Ribeiro, Andrea Fajardo Aguilar, Alyssa Harris

Undergraduate Student Symposium

There is an ongoing debate in the literature on the existence of a bilingual advantage on tests of attention. Hypothetically, bilinguals have an advantage over monolinguals on tests of attention because both attention and language control share the same inhibitory mechanism. Because bilinguals engage this mechanism more often than monolinguals, inhibitory control is believed to be stronger and confer an advantage. However, research findings on the bilingual advantage are inconsistent and attempts to reproduce prior results have sometimes failed. The argument is that studies may have failed to capture the important aspects of language linked to attention. Prior research from …


Tissue-Specific Stable Isotope Fractionation In Subarctic Pinniped Species, Morgan Michalek Apr 2026

Tissue-Specific Stable Isotope Fractionation In Subarctic Pinniped Species, Morgan Michalek

Undergraduate Student Symposium

Stable carbon (δ13C) and nitrogen (δ15N) isotope ratios are widely used to evaluate marine mammal diet, trophic position, and nutrient assimilation. However, interpretation is often confounded by tissue-specific isotopic discrimination, which alters isotope ratios during nutrient assimilation and tissue synthesis. Quantifying these offsets is essential for ensuring accurate trophic reconstructions across multiple tissues with different biochemical compositions. This study measured δ13 and δ15N values in muscle, blood, blubber, brain, collagen, kidney, liver, skin, fur, and vibrissae of Steller sea lions (Eumentopias jubatus), harbor seals (Phoca vitulina), and northern fur …


Creatine In Dementia And The Aging Brain, Dylan Kuni Apr 2026

Creatine In Dementia And The Aging Brain, Dylan Kuni

Undergraduate Student Symposium

Dementia is a syndrome that interferes with cognitive functions and an individual's ability to function independently. Dementia includes several subtypes caused by different neuropathologies, with Alzheimer's disease (AD) being the most common form. AD is characterized by the accumulation of amyloid beta plaques and neurofibrillary tau tangles in the brain, associated with neuroinflammation, oxidative stress, and deficits in energy metabolism. While treatments for AD exist, the efficacy, safety, and cost are a concern, highlighting the need for additional prevention and treatment strategies. This literature review examines the role of creatine in brain health and disease, including AD and related dementias. …


Ketone Bodies As Regulators Of Cardiac Energy Metabolism And Cardiovascular Signaling, Eera Mehrota, Anika Singh, Meghana Divi, Cynthia Chamoun, Samiksha Chemukula Apr 2026

Ketone Bodies As Regulators Of Cardiac Energy Metabolism And Cardiovascular Signaling, Eera Mehrota, Anika Singh, Meghana Divi, Cynthia Chamoun, Samiksha Chemukula

Undergraduate Student Symposium

The heart has a high and continuous energy demand and depends on metabolic flexibility to maintain function under both physiological and pathological conditions. Ketone bodies, particularly β-hydroxybutyrate, have emerged as important alternative fuels for the myocardium and as biologically active signaling molecules. This review examines how ketone bodies support cardiac energy metabolism and regulate vascular and myocardial biology through intracellular signaling pathways. A narrative synthesis of peer-reviewed literature was conducted, focusing on ketone utilization in healthy and diseased hearts, metabolic remodeling in heart failure, and the non-energetic signaling roles of ketone bodies in cardiovascular tissues. Evidence indicates that ketone bodies …


Developing New Digital Methods To Study And Improve Eyewitness Testimony, Isabella Ryan, Brianna Munoz, Adam Durnin, Tanya Schrader, Joana Vinagre Apr 2026

Developing New Digital Methods To Study And Improve Eyewitness Testimony, Isabella Ryan, Brianna Munoz, Adam Durnin, Tanya Schrader, Joana Vinagre

Undergraduate Student Symposium

Witnesses play a crucial role in criminal investigations. However, their ability to recall important details is influenced by cognitive processes such as memory. To improve eyewitness testimony, psychologists developed science-based interviewing techniques, such as the Cognitive Interview, which are used by police to elicit accurate accounts. We also created new retrieval strategies, namely the Category Clustering Recall (CCR), which has been implemented by agencies such as the Los Angeles Police Department. However, research supporting the use of these techniques predominantly used the mock-witness paradigm, where participants observed a mock-crime on a two-dimensional (2D) screen and recalled it in a controlled …


The Central Role Of Caffeine In Energy Drink Effects, Viviana Valerio, Sarah Bailey Apr 2026

The Central Role Of Caffeine In Energy Drink Effects, Viviana Valerio, Sarah Bailey

Undergraduate Student Symposium

The goal of this study was to assess the effects of caffeine in an energy drink against a caffeine-matched control on attention span. Two double-blind groups of a total of 107 subjects were formed. Each group was either assigned to the energy drink (C4 - Nutrabolt®) or a caffeine-matched control of 200 mg of caffeine. The subjects consumed the caffeine sources and waited 45 minutes. They then completed a psychomotor vigilance test (PVT), Memtrax (memory), handgrip strength, and a wall-sit endurance test. There were no differences in the improvement (pre vs. post) of the PVT test between the caffeine-matched control …


Discovery And Genome Annotation Of Tuti And Charminar: Two Newly Discovered Gordonia Rubripertincta Bacteriophages Apr 2026

Discovery And Genome Annotation Of Tuti And Charminar: Two Newly Discovered Gordonia Rubripertincta Bacteriophages

Undergraduate Student Symposium

As the most abundant organisms, bacteria are both beneficial and harmful, highlighting the significance of regulating their growth. Bacteriophages (phages) are ubiquitous viruses that require a host bacterial organism for replication, making them an essential component of the microbial ecosystem and used as tools for killing bacteria. Since their discovery in 1915, phages have been used in real-world applications including alternatives to antibiotics, diagnostic agents, pest control in agriculture, wastewater treatment, and bioremediation. Since bacteriophages remain mostly undiscovered, continued isolation and genetic characterization of novel phages are essential for advancing scientific knowledge and potential applications. Through Nova Southeastern University's SEA-PHAGES …


Functional Annotation Of Gordonia Phage Minor Tail Proteins Using Alphafold And Structural Homology Searches, Harani Athwale, Mitchell Thenor Apr 2026

Functional Annotation Of Gordonia Phage Minor Tail Proteins Using Alphafold And Structural Homology Searches, Harani Athwale, Mitchell Thenor

Undergraduate Student Symposium

Bacteriophages are viruses that infect bacteria. The basic phage structure consists of a DNA or RNA genome encased in a capsid protein shell. Some may also have a tail, important for attachment and genome delivery into the bacterial host. Recently, the structure of mycobacteriophage Bxb1 was characterized and determined to have 10 minor tail proteins, each assigned a unique function. The genomes of Gordonia rubripertincta phages Fribs8, Genamy16, Alyssamiracle, and NovaSharks were annotated, depicting several minor tai proteins. However, the specific functions were not determined. Therefore, the goal of this research was to assign a specific function to the minor …


Effects Of Invasive Water Hyacinth On Boldness And Habitat Preference In Mosquitofish, Nicolas Borca, Chancellor Rockwell Marks Apr 2026

Effects Of Invasive Water Hyacinth On Boldness And Habitat Preference In Mosquitofish, Nicolas Borca, Chancellor Rockwell Marks

Undergraduate Student Symposium

Eastern mosquitofish (Gambusia holbrooki) are small freshwater fish that play an important role in aquatic food webs. Their behavior, especially boldness and risk-taking, can change depending on the type of habitat they occupy. In this study, we investigated how mosquitofish respond behaviorally to the presence of the floating invasive plant water hyacinth by comparing their boldness, preference for cover, and predation rates between water hyacinth and its native competitor, pennywort. Fish boldness was measured using a two-factor latency experiment. Fish were collected from freshwater locations in South Florida that either had the invasive plant or were free of …


Addressing Burnout In Medical Education: A Meta-Analysis Of Florida Medical School, Riddhi Banjeree Apr 2026

Addressing Burnout In Medical Education: A Meta-Analysis Of Florida Medical School, Riddhi Banjeree

Undergraduate Student Symposium

Burnout and mental health issues in medical students in the United States have become increasingly prominent -- posing challenges for student well-being, patient care, and the future of the physician workforce. Burnout is characterized by emotional exhaustion, depersonalization, and a loss of personal accomplishment. These traits can develop early in med school, perpetuate throughout their training years, and are reinforced by demanding academic workloads, competitive exams, and emotionally taxing clinical experiences. The purpose of this project is to examine mental health, counseling, and wellness resources offered across eight medical schools in Florida - U Miami, UCF, UF, USF, FAU, FIU, …


Virtual Reefscapes: Modeling Fish Abundance On Artificial And Natural Reefs In Broward County, Jesse Caruana Snachkus Apr 2026

Virtual Reefscapes: Modeling Fish Abundance On Artificial And Natural Reefs In Broward County, Jesse Caruana Snachkus

Undergraduate Student Symposium

This project involved constructing a VR simulation of fish abundance on artificial and natural reefs in Broward County. Two environments, SS Tracey, and a section of the Florida Reef Tract, were created to highlight ecological differences between artificial and natural reef habitats. All environments and species models were designed in Blender, a 3D modeling software, and each fish species was animated to showcase naturalistic behavior. The completed assets were then assembled in VR using the Open Brush application. This project integrates art, technology, and ecology to make marine environments more accessible and engaging for a wide audience. A combination of …


Using X-Ray Crystallography To Inform Foldamer Drug Design, Isabella Garcia Apr 2026

Using X-Ray Crystallography To Inform Foldamer Drug Design, Isabella Garcia

Undergraduate Student Symposium

Foldamers are synthetic peptide oligomers that fold into well-defined three-dimensional structures, such as alpha-helices and beta-sheets. The goal of this project is to discover the solid-state confirmation of beta-amino acid foldamers that have potential as therapeutic molecules. This research represents an interdisciplinary collaboration between KAIST, a research university in South Korea, and NSU. We solved the single-crystal X-ray structures of two foldamers and then visualized their secondary structures and intermolecular contacts using Mercury. The first foldamer crystallized in the space group P21212 and demonstrated a continuous alpha-helical secondary structure, with the residue side chains evenly distributed …


Evaluating Item Discrimination And Gender-Based Differential Item Functioning In Safe Sex Behavior Questionnaire (Ssbq), Prarthana Harikrishnan, Xinlei Zhang, Hannah Scheffer Apr 2026

Evaluating Item Discrimination And Gender-Based Differential Item Functioning In Safe Sex Behavior Questionnaire (Ssbq), Prarthana Harikrishnan, Xinlei Zhang, Hannah Scheffer

Undergraduate Student Symposium

Risky sexual behavior can increase rates of sexually transmitted infections (STIs), posing a danger to the health of young adults. The Safe Sex Behavior Questionnaire (SSBQ; Dilorio et al., 1992) is a widely used measure to assess risky sexual behaviors among young adults. However, few studies have evaluated the psychometric properties of the SSBQ, such as how well the survey items discriminate between individuals who engage in safer versus riskier sexual behaviors (discrimination), and whether the items function equivalently for men versus women (differential item functioning). In the current study, we applied psychometric modeling to a dataset of 1,094 young …


Investigating Epigenetic Dysregulation Of Long Non-Coding Rnas In Glioblastoma And Glioma Stem Cells, Pujita Kellampalli, Mansi Gandhi, Dhruv Patel, Nehal Pant, Mihika Mishra, Shehr Bano, Aaron Basnyet Apr 2026

Investigating Epigenetic Dysregulation Of Long Non-Coding Rnas In Glioblastoma And Glioma Stem Cells, Pujita Kellampalli, Mansi Gandhi, Dhruv Patel, Nehal Pant, Mihika Mishra, Shehr Bano, Aaron Basnyet

Undergraduate Student Symposium

Glioblastoma multiforme (GBM) or Grade IV glioma is a very aggressive form of brain tumor with an overall survival rate of 15 months. The tumor contains glioma stem cells (GSCs) that are resistant to existing therapies. Long non-coding RNAs such as DNA methylation are implicated in epigenetic dysregulation of GBM and GSCs. In this study, we screened lncRNAs with altered DNA methylation in both tumor cells and GSCs compared to normal neural cells using 450K methylation array data. We identified 508 methylation sites (320 lncRNAs) that were either hypermethylated (or gained methylation) or hypomethylated (lost methylation) in GBM and GSCs. …


A Descriptive Survey Of Reef Fish Biodiversity At The Erojacks Artificial Reef, Dania Beach, Florida, Daniella Michelle Acosta Reyes Apr 2026

A Descriptive Survey Of Reef Fish Biodiversity At The Erojacks Artificial Reef, Dania Beach, Florida, Daniella Michelle Acosta Reyes

Undergraduate Student Symposium

South Florida has one of the highest biodiversity's of reef-associated fish species in the United States. Reef systems play a crucial role in sustaining regional biodiversity. Ongoing declines in natural coral reef systems caused by climate change, coastal development, and other anthropogenic factors have increased the reliance on artificial reefs as alternative structures for coral and fish communities to aggregate. Artificial reefs play an important role in maintaining marine biodiversity and provide habitat for reef-associated fishes. The Erojacks Reef, an artificial reef system located off the coast of Dania Beach, South Florida acts as a gathering site for reef fishes. …


A Review Of Reproductive Cycling In Batoid Dentition Morphology With New Data On Two Dasyatid Stingrays From The Western North Atlantic, Lacey Adamik Apr 2026

A Review Of Reproductive Cycling In Batoid Dentition Morphology With New Data On Two Dasyatid Stingrays From The Western North Atlantic, Lacey Adamik

Undergraduate Student Symposium

Elasmobranchs continuously replace their teeth throughout their lifespan, allowing changes in tooth morphology associated with feeding and reproduction to occur. In many batoid species, males will bite females during pre-copulatory behavior, placing male dentition under selective pressure to meet the demands of both diet and grasping of females. Previous research has documented sexual dimorphism and seasonal dentition changes in several species of batoids, suggesting that this phenomenon is widespread. Much of this research is observation-based, and quantitative studies of dentition are limited, particularly in pelagic species. Pelagic Stingray (Pteroplatytrygon violacea) specimens were previously collected by commercial fishermen, and …


Modeling The Extracellular Matrix-Like Retinal Protein Pikachurin And Its Binding To Α-Dystroglycan And Gpcr (Gpr179), Mohit Belur, Khushi Raval, Riya Chelagiri, Rani Mehta Apr 2026

Modeling The Extracellular Matrix-Like Retinal Protein Pikachurin And Its Binding To Α-Dystroglycan And Gpcr (Gpr179), Mohit Belur, Khushi Raval, Riya Chelagiri, Rani Mehta

Undergraduate Student Symposium

Pikachurin is an extracellular matrix scaffold protein that links photoreceptor and ON-bipolar cell synapses by bridging the presynaptic dystroglycan complex and the postsynaptic receptor GPR179, ensuring precise synaptic alignment required for vision. Although its role in dystroglycanopathy associated visual phenotypes is well recognized, there is no published structural model showing how pikachurin engages α-dystroglycan or how this may influence GPCR linked synaptic signaling. This study computationally modeled full length Pikachurin using the complete nucleic acid sequence and available Protein Data Bank structures, integrating Jmol, AlphaFold, and literature-based analysis to predict domain organization, Ca2+-binding motifs, and glycan interaction sites …


The Role Of Hip Internal Rotation And Ground Reaction Forces On Lower Back Pain In Amateur Golfers, Katrina Arndt Apr 2026

The Role Of Hip Internal Rotation And Ground Reaction Forces On Lower Back Pain In Amateur Golfers, Katrina Arndt

Undergraduate Student Symposium

Lower back pain (LBP) is the most common musculoskeletal injury amongst golfers; the high velocity and repetitive motion of the golf swing on the lumbar spine leads to substantial compressive and torsional forces, making LBP primarily and overuse injury. An additional risk factor for LBP is limited lead hip internal rotation (LHIR), which forces the lumbar spine to compensate through excessive rotation. The golf swing also relies heavily on the efficient transfer of energy generated from the ground through the lower body, a process quantified by ground reaction forces (GRFs). While existing research has separately examined LBP and GRFs, there …


Disease-Modifying Therapies Targeting Neuroinflammation In Alzheimer's Disease: Evaluation Of Ongoing Clinical Trials, Shree Diora, Reagan Colavita, Christa Torchia Apr 2026

Disease-Modifying Therapies Targeting Neuroinflammation In Alzheimer's Disease: Evaluation Of Ongoing Clinical Trials, Shree Diora, Reagan Colavita, Christa Torchia

Undergraduate Student Symposium

Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline and behavioral changes. While traditionally associated with amyloid-β plaques and tau tangles, growing evidence implicates neuroinflammation as a key driver of disease progression. Microglial, astrocytic, and mast cell activation, along with elevated pro-inflammatory mediators, contribute to synaptic dysfunction and neuronal loss. Targeting these pathways offers promising therapeutic avenues beyond amyloid and tau-centric strategies. This study evaluates the emerging disease-modifying therapies in clinical trials that target neuroinflammation in AD, focusing on mechanisms, trial phases, and emerging clinical findings. The clinical trial website was accessed to find drug therapies under …


Transcranial Magnetic Stimulation For Substance Use Disorder, Sarah Defrant Apr 2026

Transcranial Magnetic Stimulation For Substance Use Disorder, Sarah Defrant

Undergraduate Student Symposium

This review evaluates transcranial magnetic stimulation (TMS) as a supplemental intervention for decreasing substance use disorder (SUD) relapse rates by synthesizing understandings of neurobiological mechanisms and clinical outcomes. TMS stimulates the activity of neural cells in the dorsolateral prefrontal cortex (DLPFC), a small portion of the prefrontal cortex that houses impulse control and decision-making skills. This leads to improved neuroplasticity and dopamine regulation, both of which are disrupted by unregulated substance use. Although TMS is not FDA-approved for substance use disorder, the neurobiological similarities between SUD and its comorbidities like major depressive disorder or anxiety highlight TMS's theoretical potential to …