Digital Commons Network^™

An Unfaltering Step To The End: An Analysis Of Virginia Governor James L. Kemper's Veto Of The 1874 Petersburg Charter, Chandler Lilley

Liberty University Research Week

No abstract provided.

The Mythopoeic Translator In Peter Jackson’S The Fellowship Of The Ring, Alyssa Johnson

Liberty University Research Week

Peter Jackson's "The Lord of the Rings" films are beloved by Tolkien fans around the world. But do they hold true to Tolkien's original vision for the stories? This presentation aims to discuss the mythopoeic elements in Tolkien's books and the way that the films follow those elements through the only thing that films can have that books cannot: music. Howard Shore's film score for "The Lord of the Rings" carries the movies across the divide created by transferring a story from paper to screen. The score creates a sense of wonder and mythopoeia in the viewers that returns beautifully …

Guppy: From Fleet Boat To Modern Submarine, Nathaniel Estrada

Liberty University Research Week

World War II changed everything when it came to American submarine warfare. Before the war, American naval leaders and planners debated over what the purpose of their submarine fleet should be. The more progressive thinkers claimed the submarine would be in-of-itself a decisive combat asset, while the conservative naval minds saw their “fleet boats” as supplementary to the main battle line. When the war ended, the debate was no longer about what role the submarine would play in the great game on the sea. In the Atlantic, the German U-boat fleet of 1,131 submarines would sink 14,878,463 tons of Allied …

Over The Garden Wall And The Divine Comedy: Mchale's Modern Vision Of Purgatory, Gloria Asper

Liberty University Research Week

This paper discusses how the allusions to The Divine Comedy in Patrick McHale’s mini-series Over the Garden Wall (OTGW) influences one’s interpretation of the series. Building off the work of other OTGW scholars such as Willsey and Camacho & Menchero as well as pop culture commentators such as Trey the Explainer, I highlight parallelisms within OTGW as well as reference comments from the creators in order to demonstrate how theoretical concepts in The Divine Comedy shape the understanding of OTGW. Specifically, one such theoretical concept involves Dante’s philosophical belief that the intellect and the will must work together to create …

Mycotoxin Trends In Cannabis Flower And Concentrates In The United States, Kyle Boyar, Yasha Kahn, Michael Esposito, Sukhikh Pavel

Oxford ICSB

Mycotoxins are toxic fungal metabolites that may pose potential health risks in cannabis products, yet limited data exists on their prevalence in regulated markets. This study analyzed multi-state compliance testing data for cannabis flower and concentrates across eleven U.S. states to evaluate detection and failure rates for aflatoxins (B1, B2, G1, and G2) and ochratoxin A. Ochratoxin A was the most frequently detected mycotoxin in both flower and concentrates; however, detections rarely exceeded regulatory action limits, with overall failure rates remaining low at 0.016% for flower and 0.017% for concentrates. After excluding outlier laboratories with unusually high detection rates, true …

Canndor Herbarium: A Comprehensive Herbarium Resource For Cannabis Identity, Diversity, And Botanical Research, Nick Batora, Laura Klein, Kerin Law, Eleanor Kuntz

Oxford ICSB

Decades of cannabis prohibition have created major gaps in our understanding of cannabis biology, especially with regard to the genomic, phenotypic, and germplasm resources that are standard in other agriculturally and medicinally important crops. Herbarium collections, which serve as archival specimens that preserve plant material for long term study, are no exception. Although herbarium specimens are meant to document plant diversity, most collections contain only a narrow sampling of cannabis and do not reflect the extensive variation present in commerce or this species at large. To address this need, the Canndor Herbarium was established in 2016 as the first dedicated …

Association Of Self-Efficacy, Preceptor Teaching, And Role Modeling With Practice Preparedness In Student Nurse Practitioners, Quinton Carroll, Pi-Ming Yeh, Jean Croce Hemphill, Melessia Webb, Alex Sargsyan

Epsilon Sigma at-Large Research Conference

Purpose: Final-semester student nurse practitioners (SNPs) often report unpreparedness for practice. Little is known about which preceptor characteristics prepare students for practice. The purpose of this study was to examine whether final-semester SNPs' practice preparedness is associated with their self-efficacy and most significant preceptor’s clinical teaching effectiveness and role modeling.

Aim: To identify which student and preceptor factors are associated with and predict SNP preparedness.

Methods: Cross-sectional correlational study of final-semester SNPs (N = 83). Participants completed the New Nurse Practitioners’ Practice Preparedness Survey, New General Self-Efficacy Scale, Cleveland Clinic Teaching Effectiveness Instrument, and Role Model Apperception Tool. Analysis …

Mechanistic Insights Of Enterolactone Within 3t3-L1 Adipocyte Cells, Merritt Smith

Liberty University Research Week

Type 2 diabetes mellitus (T2D) is one of the leading causes of morbidity and mortality in the United States, with approximately 25% of healthcare expenditures directed toward its management and associated metabolic complications. In response to the urgent need for novel therapeutic strategies, recent research has focused on bioactive compounds derived from dietary sources. In light of that, we identified the plant lignan matairesinol (MA) and its gut-derived metabolite, enterolactone (ENL), as agents capable of enhancing glucose uptake in 3T3-L1 differentiated adipocytes. These results suggest that enterolactone may represent a promising dietary supplement for improving glycemic control in patients with …

Disability Studies In Historical Context: The Research Behind The Creative Writing Process, Annabelle Welch

Liberty University Research Week

This study examines the process of  writing a short story “The Shoes,” set in New Orleans during World War II, and creating a main character through the lens of research within the field of disability studies. This research is closely intertwined with my creative process of writing “The Shoes.” The first portion of the poster focuses on the city of New Orleans, Louisiana, during America’s involvement in World War II. My aim is to build a foundational understanding of the microculture in that region, especially as it was shaped and molded by the strong presence of soldiers, the heavy hand …

Evaluating Sexual Dimorphism In An Urban Neonate Regina Septemvittata Population, Arleigh Wagoner, Nathan Wilkins

Liberty University Research Week

Regina septemvittata, commonly known as Queensnakes, are broadly distributed across eastern and central North America. In adult Queensnakes, females average a greater snout-vent length (SVL) than males. Since Queensnakes exhibit size dimorphism and have short life spans and low survival rates, it was hypothesized that neonate Queensnakes begin to display a distinct sex-related difference in SVL within their first few months of life. Our study investigated growth rates of neonate Queensnakes by conducting a capture-mark-recapture (CMR) study over a three-month period (August through October; birth to first brumation) in an urban stream in Lynchburg, VA. Captured snakes were measured (SVL), …

An Evaluation Of White-Spotted Bamboo Shark (Chiloscyllium Plagiosum) Development, Madison Ashby, Alexa Ashby, Baylis Huckabay, Cyrus Harris, Emma Bron, Lydia Harris, Maia Dieken, Oliver Thomas, Will Chelberg

Liberty University Research Week

An inhabitant of the north Indo-Pacific Ocean, the whitespotted bamboo shark (Chiloscyllium plagiosum) is a demersal, ambush predator of fish and invertebrates. Despite the known abundance of C. plagiosum, there is limited diagnostic information on their growth beyond embryonic development and hatching. A population of this species under managed care provides a unique opportunity to chart growth from the respective stages of life such as egg hatchling, sub-adult, and adult life stages. Through this research, we set out to chart the growth parameters on three hatchling bamboo sharks from a weekly data collection. These parameters include weight (g), sex, pre-caudal …

Evaluation Of Cadaver Tissue Antigenicity As A Practical Teaching Tool For Immunohistochemistry, Shanice Rerrie, Jumana Rizk, Levon Shukrian, Maria Mendoza Lopez

Liberty University Research Week

Immunohistochemistry (IHC) is a core technique in biomedical research and is increasingly important for teaching at the undergraduate and graduate levels. However, teaching laboratories typically rely on animal-derived tissues because the access to fresh human specimens is restricted due to ethical concerns. The purpose of this study was to evaluate whether cadaveric tissue can retain sufficient antigenicity for immunohistochemical analysis and thereby serve as an effective and ethical teaching resource. Liver lobe and renal cortex samples (approximately 1 cm³) were collected from an 88-year-old female donor. Target proteins were selected for their established roles in vitamin D metabolism and their …

Formation Of Rosette-Like Hierarchical Structures On Cylindrical Titanium Surfaces., Cole Urquhart, Ally Doud, Michael Korn, Hector Medina

Liberty University Research Week

The purpose of this experiment was to characterize titanium-based rosettes and other micro-sized crystal formations on multiple different non-planar titanium surfaces. Rosettes are crystal structures in the titanium sulfate family. They are 20-150µm in diameter and vastly increase the surface area of the places where they are grown, which can lead to various possible applications in future research. The titanium type that was being experimented on was titanium gauze (50µm diameter). To grow titanium-based structures, two steps are involved: etching and crystal formation. Firstly, the titanium material was placed in a centrifuge tube filled with 1mL of 18M (96%) conc. …

A Bloody Window To The Past: Str Analysis Of Dna From A Bloodstained Civil War Surgical Table, Nadia Walter

Liberty University Research Week

This study aimed to generate DNA profiles from the bloody Hillsman House surgical table via STR analysis while also determining the best method of sample collection and analysis from a wooden substrate. During the Battle at Sailor’s Creek in 1865, the historical Hillsman House served as a field hospital where hundreds of Civil War soldiers were treated. In 2016, Jones and McClintock collected and analyzed samples from bloodstains on the floorboards of the house, showing that historical DNA is still viable for profiling. During this process, marks on the floorboard were presumed to be from the surgical table, which was …

Various Animal Species Microscopic Hair Analysis, Bryanna Smith

Liberty University Research Week

This research aims to determine whether animal hair characteristics can reliably differentiate various animal species, a study with potential forensic applications. Both human hair and animal hair are comprised of three key components: the cuticle (the outer coating composed of overlapping scales), the cortex (protein-rich structure that surrounds the medulla and contains pigments) and the medulla (the central core, which may be absent). The goal of this research project is to document data collected from microscopic analysis of a variety of non-domesticated animal hair/fur samples, such as bear, skunk, or wolf, to determine detailed similar and different characteristics between them …

Investigating The Natural Communities And Flora Of Candler’S Mountain, Lydia Harris, Cyrus Harris, Tyler Knick

Liberty University Research Week

Candler’s Mountain is home to a variety of natural communities and flora. With more than 1200 vascular plant species documented in Campbell County, the identification and growing historical record of local flora will support short and long-term recognition of the importance of biodiverse natural communities in central Virginia. This project seeks to (1) document flora diversity in this region, (2) further establish an herbarium teaching and research collection of representative species, and (3) advance our understanding of the flora in relation to natural communities. Identified ecological groups and community types are based upon the Virginia Department of Conservation and Recreation …

Characterization Of Peroxidase From Butternut Squash Skin: Potential Use In Bioremediation, Ava Witkowski

Liberty University Research Week

Peroxidases are present in many diverse plant species and catalyze chemical oxidations, some that may have significance in biotechnological areas like bioremediation. In several recent papers we characterizes a novel peroxidase from the skin of pumpkin that possessed desirable catalytic activities in relation to a class of environmental contaminants call fluorinated phenolics. In the course of these studies, we were able to do genomic analysis on a related plant species curcubita moscata (butternut squash) and identified a peroxidase with very similar sequence. The current study focusses on the characterization of that novel peroxidase in comparison with the pumpkin skin squash. …

Sem-Edx Analysis Of Animal Hairs For The Presence Of Metals, Sydney Stevens, David Green, George Monroe

Liberty University Research Week

No abstract provided.

Comparison Of Hypothalamic And Hippocampal Neurogenesis Across Sexes And Ages Of Mice, Chloe Jensen, Madison Reynolds, Rebecca Kinyon

Liberty University Research Week

Background: The hippocampus is primarily known for its function in learning and memory; thus, it makes sense that this is a well-established highly neurogenic zone. Recent studies have demonstrated that the hypothalamus also has neurogenic properties where there were once believed to be none. Because of these recent findings, our study aims to provide baseline data pertaining to rates of neurogenesis in the hypothalamus in comparison to the hippocampus along with distinguishing differences in these rates between males and females. Methods: Using four mice, three young and one aged female, we cryosectioned the brain to image the hippocampal and hypothalamic …

Spectroscopic Characterization Of Pfas Ligands Binding To Novel Plant Peroxidases, Vladimir Bogatov

Liberty University Research Week

No abstract provided.

Elephant's Toothpaste: A Statistical Investigation Of The Yeast-Catalyzed Decomposition Of Hydrogen Peroxide, Annaliese Defelice

Liberty University Research Week

Catalase is the main enzyme in yeast that catalyzes the popular “elephant’s toothpaste” reaction. Elephant’s toothpaste reactions often proceed using an iodide or yeast catalyst, but iodine is favored for ease of quantitative analysis. There remains little statistical data on the yeast-catalyzed hydrogen decomposition reaction. The relationship between reagent amounts and reaction rate was measured by manipulating reagent quantity while maintaining other variables. The results were graphed and fitted for linearity, indicating the relative relationship between each reagent and the overall reaction rate. There were strong positive correlations between yeast and hydrogen peroxide concentrations and reaction rate. Augmenting the volume …

Allosteric Modulation Of Faah By Tocopherols, Beatrice Pyles

Liberty University Research Week

No abstract provided.

Enzyme Kinetics Of Faah, Susanna Stell, Emma Hooks

Liberty University Research Week

Anandamide (AEA) is an endogenous ethanolamide that functions as a signaling molecule within the endocannabinoid system, a regulatory network processes including pain perception, mood regulation, appetite, and neural signaling. AEA belongs to a broader class of fatty acid ethanolamides naturally present in the body, which also includes palmitoylethanolamide (PEA) and oleoylethanolamide (OEA). The activity of AEA is tightly regulated through enzymatic degradation by fatty acid amide hydrolase (FAAH), which hydrolyzes AEA into arachidonic acid and ethanolamine, thereby terminating its signaling activity. The purpose of this study is to investigate the rate at which AEA is hydrolyzed by the FAAH enzyme …

Pilot Study: Black Tea Extract And Theaflavin Polyphenols Effects On L6 Myotubes, Elizabeth Allen

Liberty University Research Week

This research investigates bioactive polyphenol group theaflavins found in black tea and how they affect Akt signaling in skeletal muscle. The black tea polyphenols are a collection of innate compounds in Camillia sinensis, among them being the theaflavin group which is comprised of four compounds: theaflavin (TF1), theaflavin 3-gallate (TF2A), theaflavin 3’-gallate (TF2B), and theaflavin 3,3’ digallate (TF3) (He, 2017). The theaflavins group has been described as bioactive in a variety of different cellular pathways such as apoptosis, cellular division, gene expression and nutrient regulation (Li et al., 2021)(He, 2017)(Lin et al., 2007).

Previous work by Nagano et al., demonstrated …

Forensic Differentiation Of Feline Hair, Gabriel Dunn

Liberty University Research Week

No abstract provided.

Impacts Of Interspecific Competition On Stress And Body Condition In A Montane Salamander (Plethodon Hubrichti), Jason Porter, Allison Carmen

Liberty University Research Week

No abstract provided.

Quantifying Biogenic Amines In Anaerobic Porcine Liver Decomposition For Improved Pmi Estimation Using Gc/Ms, Shanice Rerrie, Faith Ekoh

Liberty University Research Week

Postmortem interval (PMI) estimation remains a central challenge in forensic science, particularly during the early stages of decomposition. Quantifying biochemical changes during tissue breakdown has emerged as a promising approach to improve accuracy in PMI determination. This study expands on earlier research that quantified the biogenic amines cadaverine (CAD), putrescine (PUT), and methylamine (MEA), which result from bacterial amino acid decarboxylation during decomposition. It specifically examines how these compounds form under anaerobic conditions over a prolonged 30-day period. Porcine liver, serving as a human tissue analog, was decomposed in sealed anaerobic chambers. Tissue samples were collected at regular intervals, homogenized, …

Music Enhances Theta Brainwave Activity Regardless Of Tuning Frequency, Robert Somerville, Davis Raz, Ersilia Mirabelli, Jettson Yarborough, Luc-Shalom Kouame

Liberty University Research Week

No abstract provided.

Differential Effects Of Curcumin And C646 On Mitogenic And Metabolic Signaling In Insulin-Stimulated Hepg2 Cells, Davis Raz, Rachael De Klerk

Liberty University Research Week

Curcumin and C646 both inhibit p300/CBP histone acetyltransferase (HAT) activity, but they differ markedly in their mechanisms, potency, and effects on cellular function. Both compounds have been investigated as modulators of the insulin-signaling pathway and have shown potential for improving insulin-signaling–related defects in experimental models. Our previous findings showed that curcumin positively impacted a metabolic pathway by reducing IRS-1 phosphorylation at S1101, a negative regulatory site, while maintaining downstream PRAS40 and RPS6 phosphorylation. Although C646 also reduced IRS-1 S1101 phosphorylation, it did not preserve downstream insulin signaling as effectively as curcumin. We hypothesized that target proteins within the mitogenic pathway, …

M.E. Bradford And American Conservatism, Avery White

Liberty University Research Week

M.E. Bradford is an often overlooked figure in American Conservatism and his unique brand of Southern traditionalist political thought should be analyzed and understood better.