Digital Commons Network^™

Presenting Complaints Among Women Who Present To A Community Health Center In Gujarat, India, Maria Trinidad Miguel

Undergraduate Student Symposium

Little is known about the frequency of presenting problems among women in rural areas of Gujarat, India have not been reported or investigated carefully. The objective of this secondary data analysis is to determine the prevalence of presenting problems among women who presented to Dr. Kiran C. Patel Multi-Specialty Hospital in Ahwa, Dang District in Gujarat, India. Demographic and descriptive statistics are presented for the analysis of reports of primary complaints recorded in patient charts over a 6-day time period (December 10-14, 2018). Patients were classified by age, gender, chief complaint, and BMI. Results of this research will inform future …

Public And Private Effects Of Cooperation On Survival And Growth, Marla Fortoul, Meghan Haas

Undergraduate Student Symposium

Cooperation plays a significant role in all aspects of life where multiple individuals interact for the purpose of survival. Cheaters do not pay the cost of cooperation and they can take advantage of cooperators. In theory, cheating should undermine cooperation as an evolutionary stable strategy. However, cooperation continues to persist in multiple biological systems. One possibility to explain the stability of cooperation is the use of an impure public good. This public good can be shared amongst everyone in a population (providing a public benefit), and is used to facilitate cooperation. However, there is a private benefit of this public …

Quantifying Neuronal Damage Via Immunofluorescence Staining In Chemotherapy Induced Peripheral Neuropathy (Cipn), Kaylee Shen, Meghana Kethireddy

Undergraduate Student Symposium

Multiple myeloma is the second most common hematological cancer of plasma cells and Bortezomib (BTZ), a proteasome inhibitor, is commonly used to treat this condition. BTZ causes debilitating Chemotherapy Induced Peripheral Neuropathy (CIPN) that results in the dose limitation or discontinuation of chemotherapy. Our study focuses on determining BTZ induced neuronal damage using PC-12 cells, derived from pheochromocytoma found in rats. PC-12 cells qualify as a viable in vitro neuronal model due to their ability to differentiate into neurons with the addition of nerve growth factor (NGF). The neuronal markers including TUBB3 (β-Tubulin), GFAP (Glial Fibrillary Acidic Protein), MBP (Myelin …

Relationship Between Countermovement Jump Power And Kick Start Biomechanics In Elite Swimmers, Caroline Oster, Angela Cicenia

Undergraduate Student Symposium

The counter movement jump (CMJ) is a commonly used test to assess lower body power. It has been shown carryover to grab and track start performances in swimming despite the fact the CMJ is performed vertically and starts are performed horizontally. Kick starts use an adjustable inclined footrest. It is unknown if CMJ is associated with kick start biomechanics. The purpose of this study was to determine the relationship between CMJ and kick start performance. Fourteen elite swimmers (males, 9; females, 5; age, 21.3 ± 1.7 yrs; height, 1.79 ± 0.08 m; mass, 77.1 ± 10.7 kg) participated. CMJ height …

Relationship Between Stance Phase Frontal Plane Kinematics And Initial Impact Forces In Collegiate Cross Country Runners, Deborah Fortino

Undergraduate Student Symposium

Result Size: 437 x 476

Rearfoot eversion (REV) and contralateral pelvis drop (CPD) play a crucial role in force absorption at impact during running. Controlling and adequately absorbing the repetitive vertical ground reaction force (vGRF) at impact is essential in injury prevention. PURPOSE: This study aimed to examine the relationships between vGRF and REV, and vGRF and CPD bilaterally in collegiate cross country runners. METHODS: Eleven asymptomatic (5 females, 6 males) NCAA Division II cross country runners (age, 19.1 ± 1.1 yrs; height, 174.2 ± 11.2 cm; mass 62.2 ± 6.2 kg; 38.3 ± 15.9 miles/wk, treadmill speed, 3.6 ± …

Risk: Health And Self Control, Julieta Murzi Vargas

Undergraduate Student Symposium

Assessing the frequency with which college students undertake behaviors that have long - lasting health impacts could help us establish better preventative programs on campuses. This research will review risky decisions associated with nutrition, sleep habits, chemically-altering substances and their use, sexual safety, and general self-preservation. People are more prone to exhibiting impatience with shortterm decisions, while too much patience for long-term decisions (Mullainathan & Thaler, 2000), therefore students may undertake future risk due to present impatience and underestimation of the weight of the future risk. The purpose of this research is to specify where and what decisions are being …

Spero, Samantha Villarroel

Undergraduate Student Symposium

“Spero” is a short film about a woman who forgets about her passion but is reminded through her memories and finds the importance of self-happiness. The film is directed by Samantha Villarroel. Other crew members and actors include Julian Glasthal, Dekel Nahum, and Zach Matthews.

The Fat Mass And Obesity-Associated Gene (Fto): Can You Overcome Bad Genetics With Diet?, Madaline Kenyon

Undergraduate Student Symposium

A single nucleotide polymorphism (SNP) in the fat mass and obesity-associated (FTO) gene is a strong predictor of obesity in humans. The FTO SNP (rs1421085) results in a T to C nucleotide substitution that may result in an increased risk for obesity in individuals who carry at least one C allele. The purpose of this investigation was to determine if body composition alterations after a 4-week diet differed between those who carried the risky C allele versus those that did not. Thirty two exercisetrained subjects completed a 4-week hypocaloric diet (i.e., decreased energy intake by ~20% from baseline). After the …

The Gap In Healthcare, Rea Ghodasra, Rudresh Patel

Undergraduate Student Symposium

In Hans Rosling’s Factfulness, he discusses “The Gap.” In his opinion, there is no true gap in society, but rather misconceptions. People tend to fail to recognize overlaps when comparing averages. When two averages are separated, they seem to have a big disparity, but in most cases when combined, there is little to no gap. Rosling also delves into the “extremes” of society, the rich and the poor. In most cases, the extremes of society only account for a small percentage of the population. The majority of the population is an average of both extremes, middle-class. Lastly, Rosling discusses …

The Political Reintegration Of Prominent Confederate Generals In The Us During Reconstruction (1865-1877), Steven Sigler

Undergraduate Student Symposium

Confederate statues across the South selectively honor white supremacist generals at the exclusion of those Confederates who endorsed Reconstruction. Further blurring the history of postwar Confederate loyalties, historical literature has not adequately addressed Confederate generals according to their beliefs and actions during the Reconstruction Era. Through the examination of three case studies (Generals James Longstreet, Joseph Wheeler, and Wade Hampton III), this paper identifies three unique groupings of Confederate generals. Some had a change of heart defending freedmen as Republicans, others waited patiently to join Congress as a Democrat, and a vocal majority actively rejected national politics during Reconstruction. These …

Unraveling Gsk-3: A Potential Target In Lung Cancer Cells, Sravani Alla, Mahima Kathiria, Vineela Nagamalla

Undergraduate Student Symposium

Lung cancer is the leading cause of cancer-related deaths among both men and women in the United States. Non-small cell lung cancer (NSCLC) is the most common form of lung cancer, accounting for 80-85% of all lung cancers. Although treatment options, such as chemotherapy, radiation therapy, or surgery, are being used to treat lung cancer patients, the 5-year survival rates in advanced stages of the cancer remains less than 15%. Therefore, there is an increasing need for new potential therapeutic targets and biomarkers in NSCLC cells. GSK-3, a regulatory protein kinase, functions to characterize many behaviors in cancer cells. GSK-3 …

Using Caenorhabditis Elegans And An Engineered Bacterium To Dissect Host Pathogen Avoidance Strategies, Ratnavi Shah, Rachel H. Ghoubrial

Undergraduate Student Symposium

Little is known about how host-pathogen interactions determine avoidance strategies. Bacterial pathogens can infect Caenorhabditis elegans via ingestion. In its natural environment, C. elegans is attracted to bacterial food sources that produce small molecules called chemoattractants. In some instances, chemoattractant are produced by bacterial pathogens. Upon ingesting these pathogens, C. elegans can become infected, and can subsequently perish. However, through aversive learning, C. elegans can learn to associate these chemoattractants with harm. This ultimately causes the worms to avoid consuming the pathogen. Evolutionary constraints have likely shaped the interplay of the attraction and learning dynamics between pathogenic bacteria and C. …

Extraction And Analysis Of Volatile Biomarkers In Oral Disease Using Solid-Phase Microextraction (Spme), Elizabeth Feldman, Sean Ide Bolet, Elizabeth Horta

Undergraduate Student Symposium

Sampling volatile biomarkers (odors) from clinical samples is a noninvasive, inexpensive, and effective method for disease detection. Although odor profiles have been utilized for the detection of cancer, acidosis, diabetes, and specific genetic disorders, their role in detecting progressive diseases is unknown. Therefore, the development of effective diagnostic tools using malodors requires technique validation during all stages of disease progression rather than end stage disease. One such progressive disease associated with overall systemic health is periodontal disease. As the 6th most common chronic disease worldwide, the presence of active end stage periodontitis has been associated with autoimmune disorders, cancer, lung …

Release Kinetics Of Anti-Sema4d Monoclonal Antibody From Alginate Beads, Nicole Levin

Undergraduate Student Symposium

Background/Introduction: The reconstruction of bone in critical size defects presents clinical challenges in cranio and oral maxillofacial surgery. The long-term goal of this project is to regenerate a resilient bone for the repair of these defects. A recent study revaled that Semaphorin 4D (Sema4D), a pleiotropic transmembrane glycoprotein, expressed by osteoclasts inhibits osteoblast differentiation. Our hypothesis holds that local delivery of anti-Sema4D monoclonal antibody (mAb) adjunct to bone-regenerative cell-therapy may enhance osteoblast differentiation. However, currently, no methodology is available for the local mAb delivery. In this study, we intended to develop a novel alginate-based anti-Sema4D-mAb delivery system. Objective: The objective …

The Myth Of The Mother: Gender Stereotypes In Custody Decisions, Anna Susol

Undergraduate Student Symposium

Today, the United States custody system operates under gender-neutral policies, in which the gender of a parent may not be used as a determinant for custody. However, maternal preference, or the tendency for judges to award custody more often to mothers than fathers, is a commonplace practice in the current legal system. This study examines the history of changing custody preferences in order to understand why, in the age of gender equality, the imbalance persists. Historically, custody preferences in the legal system reflect the cultural ethos of a patriarchal society, but major shifts owing to the industrial revolution and in …

Functional Movement Pattern Proficiency Is Similar Across Stroke Type Dominance In Collegiate Swimmers, Jessica Pokryfke

Undergraduate Student Symposium

The swimming strokes are different biomechanically and necessitate specific strength and conditioning programs for injury prevention and performance enhancement. Differences may also exist in functional movement pattern proficiency between swimmers of different strokes. The Functional Movement Screen (FMS) identifies dysfunctional movement patterns and consists of seven tests (deep squat, hurdle step, inline lunge, shoulder mobility, active straight leg raise, trunk stability push-up and rotary stability). Results may guide specific corrective exercise programs that could be implemented into team-based strength and conditioning sessions. Therefore, the aim of this study was to examine differences in functional movement pattern performance between stroke dominance …

Can You Taste Fat? A Study On The Impact Of Fat Perception On Dietary Behaviors And Adiposity, Micaela Sullivan, Alexandra Apetri

Undergraduate Student Symposium

Individuals with a higher sensitivity to the perception of fat in foods may benefit from this ability by making healthier food choices. To investigate the impact of fat perception on eating habits and health, we examined participants’ daily food intake, adiposity, and ability to distinguish between full-fat and low-fat products. Participants completed a 7-day food diary to measure dietary the amounts of daily fat, sugar, sodium, carbohydrates, protein and caloric intake. Height, weight, and hip circumference measurements were used to calculate body mass index (BMI) and body adiposity index (BAI) values. The participants’ perception of fat was measured using a …

Do Markers Of Verbal Confidence Correlate With Effect Size In Studies Of Pollution Bioindicators?, Brianna Law

Undergraduate Student Symposium

Bioindicators are organisms whose status or physiological condition are used to assess the effects of stressors such as pollution on ecosystems. Commonly used bioindicators include population-level responses in environmentally sensitive insects (e.g., Ephemeroptera, Plectoptera, and Trichoptera) and fishes (e.g., slimy sculpins, fish larvae), or specific individual-level responses such as EROD enzyme induction or fecundity. Parasites were first proposed as biological indicators of pollution in the 1990s. Parasites are ubiquitous components of aquatic ecosystems, and are known to respond to pollution: while some parasites increase in abundance in polluted areas, most exhibit decreased abundance, and polluted environments typically have species-poor parasite …

How To Take A Set Mind Out Of Mindset, Krishna Patel

Undergraduate Student Symposium

Millennials are said to be the most depressed of any generation (Denizet-Lewis, 2017). This research seeks to explore how expectations in schools may contribute to widespread depression and anxiety among college students (Agliata & Renk, 2009). Recent research has explored how mindset affects your mental, emotional, and physical health: someone with a fixed mindset believes that an individual’s qualities and traits are set in stone while someone with a growth mindset believes these qualities can be learned with time and experience (Dweck, 2007). Demonstrating how the way an individual thinks can influence the overall quality of their health in terms …

Human Gut Microbiome Composition Is Associated With Perceived Stress And Cortisol, Esha Parikh

Undergraduate Student Symposium

Recent research on the gut microbiome is calling attention to the role that the microbiome-gut-brain axis (MGBA) plays in influencing behavior. One particularly exciting, yet understudied, function of the MGBA is that alterations to the microbiome can increase stress susceptibility through increasing psychological vulnerability. While this notion is interesting, it remains largely unexplored in humans likely owing to the complex, multidisciplinary approach required to provide evidence for such a hypothesis. The current study sought to shed light on this uncertainty through connecting measures of stress and cognition in humans with gut microbiome composition. Seventeen male participants (mean age = 24, …

Metabolic Inactivation Of Angiotensin 1-7 (Ang 1-7), Mahnoor Asif, Christy Abraham

Undergraduate Student Symposium

The renin-angiotensin system (RAS) plays a role in the control of the cardiovascular system by modulating blood pressure. While Angiotensin II (Ang II) serves as a vasoconstrictor and is the most well-known of the RAS peptides, Angiotensin 1-7 (Ang 1-7) is a peptide gaining interest in its countereffects to Ang II and may serve as its antagonist. However, the rapid metabolism and subsequent inactivation of Ang 1-7 precludes its use in radioactive binding assays. For this reason, peptidase inhibitors were added to assays involving ¹²⁵I-Ang1-7 or an analog ¹²⁵I-alamandine. This study uses high pressure liquid chromatography (HPLC) to …

Rate Of Phosphate Uptake By Periphyton In The Everglades, Kiersten Monahan

Undergraduate Student Symposium

Periphyton is an essential source of primary productivity and plays a major role in the removal and short-term storage of phosphorus in the Florida Everglades. In recent decades, runoff from the Everglades Agricultural Area has caused a serious nutrient pollution problem. In the oligotrophic wetlands, the increase of phosphorus leads to the growth of species that disrupts the ecosystem. In order to gauge the response of periphyton to these environmental changes, the rate of phosphate uptake by epipelon, metaphyton, and epiphyton mats are measured following spikes of either 150, 500, or 1000 ppb of potassium phosphate. The experiment was conducted …

The Universal Mass Function And Its Applicability To Non-Cosmic Objects, Kyle Hansotia

Undergraduate Student Symposium

The universe is full of mysteries. One of these mysteries is that all objects in the cosmos—from the smallest meteors to the largest galaxy clusters—are all connected with a single mass function. This mass function is a power law with a constant slope, f(m) = k m ^-2 where is m mass and k is a normalization constant (Binggeli & Hascher 2007, "Is there a Universal Mass Function?" Publications of the Astronomical Society of the Pacific, 119, 592). This means that objects with low masses are much more common than massive objects, and that the fraction of low-to-high mass …

Vegf Induced Endothelial Marker Gene Expression In Periodontal Ligament Derived Stem Cells (Pdlscs), Shreya Patel

Undergraduate Student Symposium

Background: Establishing endothelial-cell mediated vascularization is crucial in bone tissue engineering, as blood vessels are key regulators for newly formed bone homeostasis and growth. Periodontal ligament stem cells (PDLSCs), derived from periodontal ligament tissue can differentiate into a wide range of cell types, including hepatocytes, osteoblasts, chondrocytes, and adipocytes. However, there is not much research focused on their ability to differentiate into endothelial cells. Objective: The objective of this study was to investigate the ability of PDSCs differentiate into endothelial cells. Methodology: Human PDLSCs were harvested from impacted wisdom teeth from NSU clinics. The cells were cultured using standard protocols. …

Ibrutinib Inhibits Human Cd4 T Cell Proliferation, Marla Fortoul

Undergraduate Student Symposium

Ibrutinib, is an orally active agent, which works by covalent irreversible binding to the kinase domain of Bruton’s Tyrosine Kinase (BTK). The drug is of central importance in B cell receptor signaling and is currently used to treat B cells cancers like Chronic Lymphocytic Leukemia and B Cell Lymphoma. In addition to BTK inhibition, it has been hypothesized that Ibrutinib is a target of Interleukin-2 Inducible Kinase (ITK), which is an active agent in T cell malignancies survival and proliferation. The purpose of this experiment was to determine the effect of Ibrutinib on human T cells. Peripheral blood mononuclear cells …

A Step Forward, Rolando Bolanos

Undergraduate Student Symposium

“A Step Forward” is a documentary about the personal journey about me, as I seek to become an officer of the Coast Guard to not only help pay for college, but to seek opportunities unique to that in the military in order to grow as an individual, begin an ambitious career, and to travel the world. I had encountered many challenges along the way, including a lack of confidence, being overweight, and lacking any titles or experience to help solidify my image as a leader. Despite the challenges, I have managed to not only overcome these obstacles, but I have …

Desorption Electrospray Ionization Mass Spectrometry Imaging Of Human Breast Cancer Spheroids, Elaine Ognjanovski, Heather M. Robison, Corryn E. Chini, Troy J. Comi, Seung W. Ryu, Lunan Li

Undergraduate Student Symposium

Endogenous lipid synthesis is up-regulated in cancerous tissue. The role of lipids in oncogene regulation, cancer progression, and tumorigenesis is mostly unknown. It has been well-established that culturing cells in three-dimensions (3D) is a more accurate representation of solid tumors in vivo than traditional 2D cultures. 3D cell cultures (spheroids) replicate gas and nutrient diffusion, gene expression, protein concentrations, intracellular interactions, and cell–extracellular matrix connections observed in primary tumors. Herein, we describe a desorption electrospray ionization mass spectrometry imaging (DESI-MSI) method for mapping the spatial distribution of phospholipids (PL) in human breast cancer cell (BCC) spheroids (<1 mm in diameter). This label-free chemical imaging method identified specific PL species and relative percent compositions that may play a role in biological processes occurring at the outer (e.g. invasion and metastasis) and inner regions of solid breast tumors (e.g. angiogenesis). We also compare the PL composition of BCC spheroids with PL profiles of 2D BCC cultures, identifying PL changes specific to the multi-cellular environment of the spheroid.

Entertainment, Dekel Nahum

Undergraduate Student Symposium

“Entertainment” is a short narrative film about a serial killer who finds his female victims through dating apps. The story will be told from the perspective of the killer, who films his interactions with his victims, as well as their deaths. The film will deal mostly with what happens when he unexpectedly starts to care about one woman he dates, who he ultimately ends up killing. This film is inspired by how much I hate dating apps and how creepy men on the internet are. Some of my influences are the male serial killers in the television shows “Bates Motel” …

Examining The Antibacterial Properties Of Placental Tissue Components, Sujad Younis

Undergraduate Student Symposium

As the use of antibiotics has increased, the rate of antibiotic resistance has grown leading to a pressure to develop new antibiotics. Placental tissue is known to exhibit antimicrobial activity against bacteria, making it a viable candidate for novel antibiotic development. With this knowledge in hand, various components of placental tissue were tested to determine the portions that exhibited antibacterial activity. Dried placental tissue were micronized and rehydrated. The goal of this project was to take the product and test them on multiple bacterial species, some of which are common to human skin. The bacterial species tested were Escherichia coli …

Have More, Stress Less: Relating Perceptions Of Stress To Accumulation Of Different Types Of Resources, Jazmin Bush, Austin Matthies, Avia Sutton

Undergraduate Student Symposium

The concept of a "resource" is central to research in evolutionary biology and psychology. The acquisition, accumulation, and utilization of resources determines an organism’s success in terms of both survival and reproduction, and is related to a wide variety of behaviors. Despite their obvious importance, however, "resources" remain ill-defined in the scientific literature. In some cases, the concept of a resource is captured in broad terms such as "resource accruing potential". In other cases, resources are measured in restrictively specific terms, such as parents' level of education, family income, perceived level of social support, group membership, and so on. To …