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Lead Discovery And Optimization Strategies Towards The Development Of 4(1h)-Quinolones And 1,2,3,4-Tetrahydroacridone Analogs With Antimalarial Activity, Richard Matthew Cross

USF Tampa Graduate Theses and Dissertations

The goal of our research endeavor was to successfully employ modern lead discovery and optimization strategies towards the development and identification of compounds possessing antimalarial activity. Preliminary data from in vitro screening at the Walter Reed Army Institute of Research identified several chemotypes including 4(1H)-quinolones and 1,2,3,4-tetrahydroacridones to have potent antimalarial activities. Multiple synthetic routes were devised and implemented which enabled the rapid preparation and isolation of over 400 structurally diverse 4(1H)-quinolones and 1,2,3,4-tetrahydroacridones.

Our research towards discovering and optimizing antimalarials was inspired from the severe impact malaria has had on our planet especially on impoverished countries. There are over …

Mechanistic Modeling Of Photocatalytic Water Disinfection, Omatoyo Kofi Dalrymple

USF Tampa Graduate Theses and Dissertations

The main goal of this research was to develop a mechanism-based model for photocatalytic disinfection of bacteria in water using suspended catalyst pthesiss in batch reactors. The photocatalytic disinfection process occurs as a semiconductor photocatalyst, most commonly titanium dioxide (TiO₂), is irradiated with light of wavelength less than 380 nm to produce hydroxyl radicals and other highly reactive oxidants which can inactivate microorganisms. Photocatalytic disinfection involves a complex interaction of many fundamental mechanisms such as light absorption and scattering by semiconductor pthesiss, electrochemical surface reactions, and heterogeneous colloidal stability. Current models, based largely on chemical reacting systems, do …

"A Blaze Of Light And Finery": The Victorian Theater And The Victorian Theatrical Novel, Dorinda Mari Davis

USF Tampa Graduate Theses and Dissertations

The concept of the Victorian antitheatrical prejudice is both well-established and well-respected. This paper, however, examining the Victorian theatrical novel and the Victorian theater in terms of that prejudice, finds the ready assumption of the prejudice to be problematic at best. A close look at three novels that together span the early to mid-nineteenth century shows that, far from being ubiquitous and unilateral, antitheatricality was in many cases an anomaly; indeed, many of those novelistic elements that have long been assumed to be antitheatrical address different issues altogether. Employing close readings of the novels--Jane Austen's Mansfield Park, Charles Dickens's …

"Can't Buy Me Wealth": Racial Segregation And Housing Wealth In Hillsborough County, Florida, Natalie Marie Delia Deckard

USF Tampa Graduate Theses and Dissertations

Informed by the literature regarding the gap in wealth between white and non-white households in the United States, as well as the literature on segregation and neighborhood preference, this research explores the home value component of the wealth gap in Hillsborough County, Florida. It finds that homes in Predominantly Black or Hispanic neighborhoods are not only undervalued compared to Predominantly White and heterogeneous neighborhoods, but have appreciated more slowly at least since 2000. The research also finds that buyers identifying as black or Hispanic are more likely than those identifying as white or "other" to purchase homes in Predominantly Black …

Philosophical Precursors To The Radical Enlightenment: Vignettes On The Struggle Between Philosophy And Theology From The Greeks To Leibniz With Special Emphasis On Spinoza, Anthony John Desantis

USF Tampa Graduate Theses and Dissertations

My dissertation lays out some of the chief philosophical precursors to Jonathan Israel's Radical Enlightenment. It investigates the principal question of Will Durant's The Age of Voltaire: "How did it come about that a major part of the educated classes in Europe and America has lost faith in the theology that for fifteen centuries gave supernatural sanctions and supports to the precarious and uncongenial moral code upon which Western civilization has been based?" The aim of this project is both broad and specific: the first is to provide a general history of the philosophical precursors to the Radical Enlightenment up …

The Integration Of African Muslim Minority: A Critique Of French Philosophy And Policy, Amber Nichole Dillender

USF Tampa Graduate Theses and Dissertations

The numerous images of violence perpetrated by radicalized followers of Islam, has highlighted the complexities surrounding assimilation and integration of Muslims in Western society. Since the guest worker recruitment from French African colonies initiated after World War II, France has been witness to the unanticipated development of permanent communities of African laborers, many of whom are Muslim. Despite consistent promotion of French monoculture and specifically the use of the assimilation model for integration, segregation of African Muslims has occurred. Through the construction of a single country case study, I explore integration issues surrounding the French Muslim minority communities. I seek …

A National Survey Of Instructional Strategies Used To Teach Information Systems Courses: An Exploratory Investigation, Yenni Merlin Djajalaksana

USF Tampa Graduate Theses and Dissertations

Many universities and colleges have placed increased emphasis on teaching excellence in higher education. Efforts to promote teaching excellence vary from the development of alternative new pedagogies as well as research exploring strategies to improve existing teaching practices. Logically, different disciplines employ different instructional strategies to prepare their graduates with specific skills, knowledge, and attitudes. This study examined the instructional strategies used most frequently in the information systems discipline and was inspired by Shulman's (2005) concept of signature pedagogies - the unique but pervasive ways of teaching within a discipline or profession.

This dissertation reports a national survey of instructional …

Up In The Air: The Global Economy, Economic Development, And Air Transportation In Tampa Bay, Florida, Clinton M. Elbow

USF Tampa Graduate Theses and Dissertations

A globally integrated economy is one of the most prominent features of globalization and how city stakeholders respond to the global economy varies from city to city. Connecting to the global economy is often portrayed to be necessary for the continued economic development of a metropolitan area. Large transportation infrastructures such as airports represent one of the most visible ways of connecting to the global economy. Decisions made by city stakeholders regarding airports in order to reposition their city in the global economy have profound consequences for its residents. This thesis aims to examine the role played by air transportation …

Shifting Blackness: How The Arts Revolutionize Black Identity In The Postmodern West, Reginald Eldridge Jr

USF Tampa Graduate Theses and Dissertations

The contemporary experiences of racially marginalized people in the West are affected deeply by the hegemonic capitalist Orthodox cultural codes, or episteme, in which blackness operates as the symbol of Chaos. As it relates to people of African descent, these affects are marked by a denial of the black person's full status as an unproblematic subject, by ontological voids arising from the practice of enslavement over the past centuries, and by problems of representation within the West, where examples and points of reference for black identity are always tied up with conflicting interests.

Utilizing Sylvia Wynter's model of the Ceremony …

Impact Of A Wellness Clinic Visit On Cardiovascular Risk Biomarkers In Employees Of A Va Medical Center, Margaret Asomaning

USF Tampa Graduate Theses and Dissertations

Background: Worksite screening programs are increasingly being provided by employers as a means to reduce cardiovascular risk in employees. A screening program that consists of fasting serum analysis of glucose plus a lipid panel is offered yearly to employees at the VA medical center in Tampa. A retrospective study was conducted to determine if a wellness clinic exposure resulted in significant changes in employees' markers of cardiovascular risk.

Methods: Computerized records were used to follow serial outcomes for glucose, triglycerides, HDL cholesterol, and LDL cholesterol in employees whose screening results showed abnormal levels of one or more of …

Captivating The Captors: Re-Defining Masculinity, Identity And Post-Colonialism In Plutarch's Parallel Lives, Andrea Lea Pittard

USF Tampa Graduate Theses and Dissertations

This thesis investigates 1st-2nd century CE biographer and philosopher, Plutarch's, manipulation and construction of gender ideals in three sets of his Parallel Lives, Coriolanus and Alcibiades, Pelopidas and Marcellus, and Phocion and Cato the Younger in which he presented his particular version of the ideal man and route to manhood. Plutarch discouraged traditional paths to gaining masculine status and simultaneously promoted a type of masculinity that benefited other aspects of his identity, particularly promoting his social and economic position and ethnicity. He asserted throughout that martial men were not in control of their emotions and therefore were incomplete men. …

Sequential Anaerobic And Algal Membrane Bioreactor (A2mbr) System For Sustainable Sanitation And Resource Recovery From Domestic Wastewater, Ana Lucia Prieto

USF Tampa Graduate Theses and Dissertations

An innovative wastewater treatment technology was developed to recover renewable resources, such as water, energy and nutrients, from sewage. First, a novel synthetic sewage was evaluated for its suitability to serve as an alternative substrate for lab-scale wastewater treatment (WWT) research. Based on granular dried cat food, Complex Organic Particulate Artificial Sewage (COPAS) is a commercially-available, flexible, and easy to preserve feed. Characteristics of COPAS, namely chemical composition, disintegration/dissolution kinetics, and anaerobic biodegradability, were determined. Anaerobic bioassays indicate that COPAS is highly biodegradable at the concentration used to simulate household sewage (1000 mg/L), with more than 72% of the theoretical …

Realizing Virtuality: Tracing The Contours Of Digital Culture, Nicholas Andrew Riggs

USF Tampa Graduate Theses and Dissertations

People connect digitally through social media, fusing their relationships with meaning in a non-space of relational potential--a translucent and fluctuating enclave where the self becomes elastic. This thesis explores how I have formed bonds in virtual space through ritual interaction. Looking at the ways I learned to use technology through the progression of a close personal relationship, I suggest that social media use is a performance of identity--a virtuality that exposes how people negotiate the digital enclosure of contemporary society. My story is one of digital nativity and reclaiming love through virtual performance. I show how these performances have had …

The Performance Production Process Of An Outstanding High School Choir, Kathy K. Rolsten

USF Tampa Graduate Theses and Dissertations

Despite the interest in and importance of producing high quality choral performance, the question "How is superior performance produced?" has not been addressed in a holistic and naturalistic way. A synthesis of previous research findings suggests that a combination of actions, interactions, relationships, and conditions produce superior choral performance. Yet a holistic examination of this multi-faceted production process has not been conducted. In order to identify all factors contributing to the production of superior performance and how these factors work together, I comprehensively examined an extreme case of superior performance. This extreme case of superior performance was one high school, …

The Relationship Between Statistics Self-Efficacy, Statistics Anxiety, And Performance In An Introductory Graduate Statistics Course, William Ray Schneider

USF Tampa Graduate Theses and Dissertations

The purpose of this study was to determine the relationship between statistics self-efficacy, statistics anxiety, and performance in introductory graduate statistics courses. The study design compared two statistics self-efficacy measures developed by Finney and Schraw (2003), a statistics anxiety measure developed by Cruise and Wilkins (1980), and a course performance measure. To view self-efficacy from two perspectives, the Current Statistics Self-Efficacy (CSSE) assessed student confidence in their ability to complete specific statistics tasks in the present, whereas Self-Efficacy to Learn Statistics (SELS) assessed student confidence in their ability to learn statistics in the future. The performance measure was the combined …

The Impact Of Paternalism And Organizational Collectivism In Multinational And Family-Owned Firms In Turkey, Jennifer Schroeder

USF Tampa Graduate Theses and Dissertations

This correlational study examined the influences of paternalistic leadership behavior (PL) and organizational collectivism (measured at the employee level) on employee reported LMX, job satisfaction and organizational citizenship behaviors (OCBs) in two types of organizations (family-owned firms and multinational organizations) in Turkey. Survey data were collected from (N = 154) employees in family-owned and (N = 159) employees in multinational firms (MNCs). Employees in family-owned firms reported significantly higher levels of PL, organizational collectivism, LMX, and OCBs. Further examination revealed additional differences by organization type, with the family-owned sample showing no significant relationships between study variables and OCBs, in contrast …

Institutional Investors And Corporate Financial Policies, Ricky William Scott

USF Tampa Graduate Theses and Dissertations

Institutional investors influence corporate payout and research and development (R&D) investment policies. Higher payouts are encouraged by institutional investors, especially in firms with high free cash flow and poor investment opportunities. They also positively influence stock repurchases, particularly in firms with high information asymmetry. The substitution of stock repurchases for dividends as a percentage of total payout is encouraged by institutional investors. Institutional owners persuade firm management to increase research and development (R&D) investment overall and specifically in firms with higher stock liquidity, higher information asymmetry, lower free cash flow, and better investment opportunities. Institutional investors decrease agency costs in …

Parent Involvement In Children's Schooling: An Investigation Of Measurement Equivalence Across Ethnic Groups, Heather Marie Scott

USF Tampa Graduate Theses and Dissertations

Epstein et al.'s Theory of Overlapping Spheres of Influence focuses on the interaction and communication, or partnerships, among families, schools, and the community to bring the three closer together. The theory works in conjunction with Epstein's typology of parental involvement, which focuses on six types of involvement that are instrumental to a child's development and his/her school and educational success. These serve as the framework for the study and support the construct of parent's involvement in children's schooling.

The purpose of the current study was to conduct further validation analyses of an inventory designed to measure the construct of parent …

A Multi-Methodological Study Of A Possible Syndemic Among Female Adult Flim Actresses, Candace Danielle Sibley

USF Tampa Graduate Theses and Dissertations

Existing literature provides support for a possible syndemic among adult film actresses. Multiple studies emphasize that a combination of economic, social, and cultural issues work together in tandem to synergistically amplify HIV/STI risk in this vulnerable population. It is critical to acknowledge how the detrimental effects of the high prevalence of substance abuse, psychological distress, intimate partner violence, and childhood sexual abuse work together in a system to heighten HIV/STI risk among adult-film actresses. Additionally, issues including the retrogressive dynamic and unequal power and hegemony in the industry function as facilitators which lower the overall health profile of adult-film actresses. …

El Poder / The Power: Latino/A Literature Inclusion In The Florida High School Language Arts Classroom As A Contributing Deterrent To The Latino/A Dropout Rate, Monica Adriana Sleeter

USF Tampa Graduate Theses and Dissertations

Curricula throughout the country, specifically in the School District of Hillsborough County (SDHC), do not encompass diverse subject matter as it relates to Latino/a students. The primary argument posed in this thesis is that consistent engagement to Latino/a writings in the English language arts classroom can be a positive force that contributes to an increased rate of retention of Latino/a youths in high school and a higher percentage of Latino/a high school graduates. This Latino/a literature can be in the form of supplementary reading material that teachers will have access to that will include Latino/a literature from various authors that …

Perspective Shifting In Relative Clauses By Elementary-Aged Spanish-English Bilinguals: A Cross-Linguistic Study, Xigrid Tayri Soto

USF Tampa Graduate Theses and Dissertations

Language-specific theories of sentence processing suggest that individuals interpret sentences based on the characteristics of their native language (e.g., Bates & MacWhinney, 1989). As such, competing linguistic cues are taken into account (including word order, morphology, and animacy) and the cue selected is most likely to yield a correct interpretation in the native language. However, research in this area has produced conflicting results. MacWhinney (2005) has proposed that examining the role of perspective shifting in sentence comprehension may demonstrate how cognitive and syntactic factors work together to facilitate sentence comprehension. The aim of the current study is to investigate the …

Pilot Assessment Of Novel Membrane Bioreactor Processes - Improvements In Biological Nutrient Removal And Membrane Operation, Shaleena Smith

USF Tampa Graduate Theses and Dissertations

With increasing water reuse applications and upcoming stringent regulations for treated wastewater effluent discharge, wastewater plants need to consider alternative technologies beyond conventional treatment processes. The new regulations, Numeric Nutrient Criteria (NNC), may regulate discharge nitrogen and phosphorus concentrations to as low as 0.5 mg/L as N and 10 μg/L as P respectively. To meet these target requirements, system retrofitting to incorporate chemical or advanced nutrient removal systems possibly with membrane technology will most likely be required. Although microfiltration/ultrafiltration membranes coupled with biological processes, otherwise known as membrane bioreactors (MBR), remove contaminants and suspended solids, nutrient removal is minimal to …

National Identity, Gender, And Genre: The Multiple Marginalization Of Lotte Reiniger And The Adventures Of Prince Achmed (1926), K. Vivian Taylor

USF Tampa Graduate Theses and Dissertations

Contemporary American visual culture is saturated with animation, from websites and advertisements to adult and children's television programs. Animated films have dominated the American box office since Toy Story (1995) and show no signs of relenting, as demonstrated by Up (2009) and Alice in Wonderland (2010). Scholarly interest in animation has paralleled the steady rise of the popularity of the medium. Publications addressing animation have migrated from niche journals, such as such as Animation Journal and Wide Angle, to one of the most mainstream English-language publications, the Modern Language Association's Profession, which included Judith Halberstam's article "Animation" in …

A Comparison Of Latina Women In Centeringpregnancy And Individual Prenatal Care, Tara E. Trudnak

USF Tampa Graduate Theses and Dissertations

CenteringPregnancy is a model of group prenatal care that replaces routine, individual prenatal care. The program brings women together into small groups to receive their care and prenatal education, and is based on three components: risk assessment, education, and support. The model is client-centered, designed to empower pregnant women and support persons, and involves the woman in small group discussions of 8-10 other women of similar gestational age. The group discussions provide support, help women educate each other, and invoke self-monitoring. Currently, there have been few publications that closely examined maternal weight and obesity and associated outcomes in women involved …

The Role Of Program Climate And Socialization In The Retention Of Engineering Undergraduates, Heather Elizabeth Ureksoy

USF Tampa Graduate Theses and Dissertations

Increasing women's participation in the fields of science, technology, engineering and mathematics (STEM) can promote a healthy economy by ensuring a diverse and well-qualified STEM workforce, not only in the quantity of females in the workforce, but diversity in thinking and creativity. It will also send a positive message to young women about the breadth of educational opportunities and career choices they have available to them. However, women continue to participate in engineering education in a far lower rate than men. Attracting and retaining female students has become a challenging problem for the academic engineering community. In this study, a …

School Psychologists' Communication And Collaboration With Community-Based Mental Health Professionals, Audra St. John Walsh

USF Tampa Graduate Theses and Dissertations

Although collaboration between school psychologists and community-based mental health professionals is essential in the provision of comprehensive and effective mental health services for youth with intensive mental health needs, youth may not receive the full benefit of these coordinated efforts, as collaboration may not occur as often as it should. This study investigated the frequency of communication and collaboration between school- and community-based professionals, the purposes and methods of communication, and the benefits and barriers to collaboration. Survey data from 80 members of the Florida Association of School Psychologists were collected and analyzed. Forty-three percent of school psychologists reported communicating …

Painting Parisian Identity: Place And Subjectivity In Fin-De-Siecle Art, Chelsea Anne Watts

USF Tampa Graduate Theses and Dissertations

In this thesis I provide analysis of several nineteenth-century artworks in order to elucidate the connections between place and identity as expressed in visual representations of Paris. I utilize Bakhtin's idea of the dialogical as a means of identifying multiple subject positions that might be accessed by particular individuals who live in socially constructed spaces specific to fin-de-siècle Paris. I discuss the construction of three performed identities unique to nineteenth-century Paris: the Flâneur, the bohemian, and the primitivist. In each chapter I will parse out the social construction of the spaces where these identities existed and were performed, and link …

The African American Women's Summit: A Case Study Of A Professional Development Program Developed By And For African American Women Student Affairs Professionals, Nicole Mary-Ella West

USF Tampa Graduate Theses and Dissertations

While African American women have been participating in American higher education for more than a century, they remain significantly underrepresented among college and university administrators. Researchers have noted that when these women are able to secure administrative positions, many of them contend with intense isolation and marginalization, which compromises their personal well-being and jeopardizes their professional success. Black feminist scholars have suggested that African American women may be assisted by involving themselves in supportive networks that provide them the opportunity to connect with other African American women. Further, these scholars contend that these activities should be facilitated by African American …

Detection Of Polybrominated Diphenyl Ethers In Ambient Air At A Wastewater Treatment Facility In Tampa, Florida, Brenda L. White

USF Tampa Graduate Theses and Dissertations

The goal of this study was to quantify the ambient air concentrations of polybrominated diphenyl ethers (PBDEs) from three locations within the Howard Curren Wastewater Treatment Facility located in Tampa, Florida. PBDEs have been linked to endocrine disruption, cancer, developmental concerns in children, as well as other toxic effects; however their precise roles concerning these deleterious effects remains to be determined. The present study was motivated by these potential health concerns posed by inhalational exposure to PBDEs. Ambient air was monitored with a Tisch Environmental PUF high volume sampler for 48 hours with collection on three types of media-quarts filter, …

A Descriptive Study Of The Factors That Prevent Principal Candidates From Advancement To The Principal Position, Robyn Regina Witcher

USF Tampa Graduate Theses and Dissertations

This qualitative study examined the perceived barriers to the principalship by prepared principal candidates as a means of understanding why some candidates are unsuccessful in acquiring a principalship. The use of a questionnaire, interviews, and reflection postcards served as the data collection methods concerning their lack of success in achieving a principal position. Portraitures were used to illuminate the journey of these candidates as they completed the necessary requirements, developed the skill vital to becoming a principal, and interviewed for prospective openings.

The findings revealed that the barrier to the principalship for these candidates is their own lack of awareness …