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USF Tampa Graduate Theses and Dissertations

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Factors Related To Hearing Aid Use Among Older Adults From Hispanic/Latino Backgrounds: Findings From The Hispanic Community Health Study/Study Of Latinos, Michelle L. Arnold Jul 2018

Factors Related To Hearing Aid Use Among Older Adults From Hispanic/Latino Backgrounds: Findings From The Hispanic Community Health Study/Study Of Latinos, Michelle L. Arnold

USF Tampa Graduate Theses and Dissertations

The purpose of this dissertation was to understand perceived hearing loss and hearing health care use among older adults from Hispanic/Latino backgrounds using the Andersen model of health care utilization as a framework. A cross sectional analysis of audiometric and survey data from the Hispanic Community Health Study/Study of Latinos was used to estimate factors that characterize perceived hearing handicap and hearing aid use, and to determine hearing aid use rates in a large group of older Hispanic/Latino adults. Data came from 6970 adults aged 45 to 76. Results revealed that self-perceived hearing handicap is significantly correlated to measured hearing …


De Mestizas A Indígenas: Reindigenization As A Political Strategy In Ecuador, Pamela X. Pareja Jun 2018

De Mestizas A Indígenas: Reindigenization As A Political Strategy In Ecuador, Pamela X. Pareja

USF Tampa Graduate Theses and Dissertations

The 1990s were a period of intense socio-economic upheaval in Ecuador, in part due to the numerous protests that would come to be known as the Levantamiento Indígena. Notoriously disenfranchised since the bloody conquest of the Americas, peoples of various Indigenous nationalities that reside within Ecuador fought for the constitutional recognition of the nation as both plurinational and multicultural, in order to secure intercultural public policies that would affect patterns of agrarian distribution, indigenous education, health, and overall representation. The prominence of the Indigenous movement and the revalorization of the Indigenous identity throughout Ecuador became an attractive vehicle for which …


The Nutrition Transition Among The Andean Kichwas Of Ecuador, Vanessa Alicia Chee Jun 2018

The Nutrition Transition Among The Andean Kichwas Of Ecuador, Vanessa Alicia Chee

USF Tampa Graduate Theses and Dissertations

The nutrition transition is a global phenomenon in which diets have become increasingly westernized and processed while lifestyles have shifted from labor intensive to sedentary, largely on account of the advent of technology, globalization n and urbanization. Despite the prevalence of this phenomenon, very little is known regarding how the nutrition transition has affected the risk of comorbid chronic diseases among indigenous Kichwas communities in Ecuador. Aims of this study are : 1) Identify specific health outcomes (such as diabetes, hypertension, and high cholesterol) associated with the lifestyle risk factors of the nutrition transition among the Andean Kichwas indigenous population; …


An Analysis Of Organ Donation Presentations On Weibo, Shengfei Li Jun 2018

An Analysis Of Organ Donation Presentations On Weibo, Shengfei Li

USF Tampa Graduate Theses and Dissertations

This thesis analyzes the presentation of organ donation organization on Weibo. This study used content analysis to find out the Love.Hope organ donation organization’s main content of Weibo’s content.

The main content includes six themes. The theme of popularizing organ donation knowledge is the majority. Through analyzing the correlation of content of each themes with shares, likes, and comments. It is concluded that people are more inclined to engage with Weibo posts with popularization of organ donation knowledge and stories of organ donors and recipients, and people also concern about the organ supply and demand situation in China.

It turns …


Ripple Effects Of The Belo Monte Dam: A Syndemic Approach To Addressing Health Impacts For The Downstream Community Of Gurupá, Cynthia A. Pace Jun 2018

Ripple Effects Of The Belo Monte Dam: A Syndemic Approach To Addressing Health Impacts For The Downstream Community Of Gurupá, Cynthia A. Pace

USF Tampa Graduate Theses and Dissertations

This dissertation examines the public health impacts of a large dam project on a downstream community using the framework of Syndemic Theory. The particular focus is the Belo Monte Dam, located in the Brazilian Amazon, and its impact on the community of Gurupá, Pará. At the present time the Belo Monte Dam, which is nearing completion, stands out in scale as being the world’s third largest dam complex. Gurupá is a community well known (and well-studied) in the social science literature as Amazon Town. The aims of this study are to assess the pre-existing public health of Gurupá, as well …


Synthesis, Oxidation, And Distribution Of Polyphenols In Strawberry Fruit During Cold Storage, Katrina E. Kelly Jun 2018

Synthesis, Oxidation, And Distribution Of Polyphenols In Strawberry Fruit During Cold Storage, Katrina E. Kelly

USF Tampa Graduate Theses and Dissertations

Plants inherently produce polyphenols (i.e., antioxidants) as a response to reduce oxidative stress caused by abusive environmental pre- and postharvest conditions. These antioxidants, as well as vitamin C, are present in considerable levels in strawberries; however, excessive oxidative stress brought on by improper postharvest handling conditions can reduce the levels of antioxidants in the fruit and shorten the shelf-life of strawberries. Nevertheless, it may be possible to utilize strawberry’s naturally occurring polyphenols to reduce postharvest stress and extend their shelf life. The polyphenolic profile has been previously investigated in several strawberry cultivars, however no studies have determined the unique polyphenolic …


Caregiver Perception And The Role Of Seasonality In Under-Five Childhood Diarrhea Incidence In Svay Rieng Province, Cambodia, Brian S. Wells Jun 2018

Caregiver Perception And The Role Of Seasonality In Under-Five Childhood Diarrhea Incidence In Svay Rieng Province, Cambodia, Brian S. Wells

USF Tampa Graduate Theses and Dissertations

Diarrheal disease has long been known to be a burden to children worldwide. Although child mortality rates as a result of diarrhea have decreased over the past two decades, overall diarrhea incidence has remained relatively stable. In Cambodia, diarrhea was the third most prevalent outpatient diagnosis for children under five in 2012, with a reported incidence rate of 12 per 100 children, up from 7 per 100 children in 2008 (Ministry of Planning Cambodia, 2012). Cambodia is an agricultural country with 80% of the population living in rural areas (National Institute of Statistics Ministry of Planning, 2013). Many are also …


Perceptions Of Quality Of Life, Peer Relationships, And Health Literacy In Adolescents With Phenylketonuria (Pku), Katherine L. Wesley May 2018

Perceptions Of Quality Of Life, Peer Relationships, And Health Literacy In Adolescents With Phenylketonuria (Pku), Katherine L. Wesley

USF Tampa Graduate Theses and Dissertations

Phenylketonuria (PKU) is a rare inborn error of metabolism that can be managed through lifelong treatment adherence to a restricted diet and supplemental medical formula (Vockley et al., 2014). Untreated PKU can result in severe intellectual disability, anxiety, depression, executive functioning deficits, and seizures (Cappelletti et al., 2013; Moyle et al., 2007). Even individuals who are continuously treated for PKU can experience high rates of anxiety and depression, executive functioning deficits, social difficulties, and lower full-scale IQ scores than their siblings and parents (Bosch et al., 2015; Manti et al., 2016; Waisbren et al., 2007). Additionally, adolescents are at risk …


A Behavioral Analysis Of Households Using Reclaimed Water In Irrigation: Case Of Pinellas County, Florida, Natalie Kuraya-Ziyadeh May 2018

A Behavioral Analysis Of Households Using Reclaimed Water In Irrigation: Case Of Pinellas County, Florida, Natalie Kuraya-Ziyadeh

USF Tampa Graduate Theses and Dissertations

In order to tend to the world’s dwindling freshwater supplies, sustainable alternative methods need to be integrated in order to keep up with the world’s increasing demand. Reclaimed water (RW) is one of the sustainable methods adopted by some Floridian cities such as Tampa, Tallahassee, and St. Pete that provide an alternative water source for non-potable uses. However, despite this alleviating effect RW has on freshwater supplies, it is crucial to recognize the potential harm it poses on neighboring waterbodies due to the residual contaminants it still contains, including Nitrogen (N) and Phosphorous (P). As such, studying residents’ knowledge and …


Do All “Good Mothers” Breastfeed? How African American Mothers’ Values And Experiences Of Early Motherhood Influence Their Infant Feeding Choices, Airia S. Papadopoulos May 2018

Do All “Good Mothers” Breastfeed? How African American Mothers’ Values And Experiences Of Early Motherhood Influence Their Infant Feeding Choices, Airia S. Papadopoulos

USF Tampa Graduate Theses and Dissertations

The food an infant is fed can reflect many things: a source of nutrition, the social and cultural circumstances into which an infant is born, or even a family’s beliefs about the body and breast milk as a source of nutrition. Exclusive breastfeeding, currently the gold standard for infant feeding in the United States (US), is often identified as an expectation in discourses on being a “good mother.” African American mothers in particular are the least likely group in the US to breastfeed in any capacity and many efforts are underway to increase the breastfeeding rates of this population.

This …


Monetary Reinforcement For Increasing Walking In Adults With Intellectual Disabilities, Diego Valbuena Apr 2018

Monetary Reinforcement For Increasing Walking In Adults With Intellectual Disabilities, Diego Valbuena

USF Tampa Graduate Theses and Dissertations

Physical inactivity is a widespread problem associated with numerous health problems. Individuals with intellectual disabilities are at a high risk of living a sedentary lifestyle. Although a few studies have examined interventions consisting of goal-setting and reinforcement for increasing PA, no studies have evaluated the use of monetary reinforcement. Interventions using monetary reinforcement have been shown to be effective for increasing PA with typically developing adults. The present studies evaluated monetary reinforcement for increasing PA in adults with intellectual disabilities. Study 1 evaluate a session-based intervention where participants earned monetary rewards for attaining step count goals as recorded by pedometers. …


Tgf-Β2 In Human Milk Research: Exploration Of A New Field Methodology And New Findings Of Biosimilar Tgf-Β2 In Non-Human Milk, Chlöe A. Sweetman Apr 2018

Tgf-Β2 In Human Milk Research: Exploration Of A New Field Methodology And New Findings Of Biosimilar Tgf-Β2 In Non-Human Milk, Chlöe A. Sweetman

USF Tampa Graduate Theses and Dissertations

Objectives: There are three aims for this thesis: the first is to develop a field and laboratory protocol for the storage and analysis of transforming growth factor–beta 2 (TGF-β2) in human breastmilk; second, to validate this protocol and the immunoassay used to assess this new method; and lastly, to explore the ramifications of biosimilar TGF-β2 across multiple milks on human health, growth, and immunity through the review of laboratory findings and previous literature.

Rational: Little anthropological research has been done on TGF-β2 in human milk. Anthropology as a discipline is well positioned to provide insight into TGF-β2, combining biocultural, evolutionary, …


Assessing Readiness To Seek Formal Mental Health Services: Development And Initial Validation Of The Mental Health Belief Model Assessment (Mhbma), Jennifer A. Greene Mar 2018

Assessing Readiness To Seek Formal Mental Health Services: Development And Initial Validation Of The Mental Health Belief Model Assessment (Mhbma), Jennifer A. Greene

USF Tampa Graduate Theses and Dissertations

Only a small percentage of people with mental health issues utilize mental health services. This would seem contradictory given the increasing understanding of mental disorders, their high prevalence, and associated disability and distress. Research shows that individual level factors, such as perceptions of need, mental health knowledge, mental health attitudes, and mental health literacy, are related to individuals’ decisions to seek mental health services. The Health Belief Model (HBM) posits four types of health beliefs that affect an individual’s health behavior, in this case, the decision to seek mental health services. To date, researchers and clinicians have no assessment tool …


Selection Of Energy Systems In Aquaculture Through A Decision Support Tool Considering Economic And Environmental Sustainability, Youngwoon Kim Mar 2018

Selection Of Energy Systems In Aquaculture Through A Decision Support Tool Considering Economic And Environmental Sustainability, Youngwoon Kim

USF Tampa Graduate Theses and Dissertations

Aquaculture had already been distinguished as an important component of global food security and economics. However, aquaculture has expanded at the cost of natural resources and the environment. The vulnerability of the aquaculture industry due to the consequences of global environmental changes and energy price fluctuations has been addressed in various studies. The identification, planning, and implementation of sustainable energy systems are important to ensure the long term economic and environmental sustainability of aquaculture.

This research investigated sustainable energy systems for aquaculture using a life cycle approach, allowing for the identification of the most sustainable energy options under different geographical …


Molecular Phylogenetics Of Floridian Boletes, Arian Farid Mar 2018

Molecular Phylogenetics Of Floridian Boletes, Arian Farid

USF Tampa Graduate Theses and Dissertations

The boletes are macrofungi which have undergone extensive taxonomic revisions since the advent of molecular tools. To further our understanding of the boletes in peninsular Florida, we sequenced two common Floridian boletes, and analyzed them with molecular phylogenetic tools. Boletus rubricitrinus, a common Florida bolete often found in lawns under Quercus, and likely has a distribution that extends to Texas. Based on ITS and LSU sequences and morphological studies, this species belongs in the genus Pulchroboletus. As the holotype is in poor condition, an epitype is established here. A thorough description of macroscopic and microscopic features is also provided for …


Identification Of Regulatory Mirnas Associated With Ethanol-Induced Microglial Activation Using Integrated Proteomic And Transcriptomic Approaches, Brandi Jo Cook Mar 2018

Identification Of Regulatory Mirnas Associated With Ethanol-Induced Microglial Activation Using Integrated Proteomic And Transcriptomic Approaches, Brandi Jo Cook

USF Tampa Graduate Theses and Dissertations

Chronic consumption of, and acute intoxication from, alcohol can have profound effects on the functional integrity of the central nervous system (CNS). The resident immunomodulatory cells of the CNS, microglia, provide signaling factors with both pro- and anti-inflammatory effects for protection. Microglial activation ranges through a multiplex of phases, of which have yet to be defined when induced by exposure to alcohol, and how the activation impacts surrounding cells. Exposure of alcohol has been revealed to induce an immune response in microglia, which can exhibit characteristics unique to a pro-inflammatory response depending on dose and time of alcohol exposure. To …


Impact Of Obesity And Expression Of Obesity-Related Genes In The Progression Of Prostate Cancer In African American Men, Mmadili Nancy Ilozumba Mar 2018

Impact Of Obesity And Expression Of Obesity-Related Genes In The Progression Of Prostate Cancer In African American Men, Mmadili Nancy Ilozumba

USF Tampa Graduate Theses and Dissertations

In the US, the incidence and mortality rates of prostate cancer (PCa) are higher among African American men compared to European American men. Obesity is an important risk factor of PCa. Obesity is known to alter the gene expression profiles in prostate tumors. This study evaluates the impact of obesity and the expression of obesity-related genes on the progression of PCa in African American men.

The primary outcome of interest is biochemical recurrence (BCR) of PCa. There were 48 African American prostate cancer patients in the study. The tissue samples included 42 normal tissues, 40 Prostate Intraepithelial Neoplasia (PIN) and …


Food Insecurity And Age Of Menarche: Using A Biocultural Approach And Life History Theory To Assess Risks Of Food Insecurity Among Girls In Tampa Bay, Fl, Mecca Burris Mar 2018

Food Insecurity And Age Of Menarche: Using A Biocultural Approach And Life History Theory To Assess Risks Of Food Insecurity Among Girls In Tampa Bay, Fl, Mecca Burris

USF Tampa Graduate Theses and Dissertations

Using life-history theory within a biocultural perspective, this research explores whether household food insecurity correlates with early or delayed menarche among adolescent females in Tampa Bay, Florida. Early onset of puberty and menstruation is connected with numerous health consequences including growth stunting, obesity, type-2 diabetes, adult-onset asthma, reproductive cancers, increased risk for depression, behavioral problems, and early sexual activity which increases the risk for STIs and ovarian cancer. Early menarche also seems to disproportionally impact disadvantaged and minority groups. While there are many known factors that influence age at menarche (e.g.: genetics, diet), little is understood regarding the effect of …


Ecosystem Function And Phenotypic Variation In Spartina Alterniflora Salt Marshes, Sandra E. Voors Mar 2018

Ecosystem Function And Phenotypic Variation In Spartina Alterniflora Salt Marshes, Sandra E. Voors

USF Tampa Graduate Theses and Dissertations

Biodiversity is important to ecosystem function at many scales, and variation functional traits within a species can potentially influence ecosystem functioning by altering nutrient cycling dynamics. High population extinction rates are resulting in a rapid loss of within-species biodiversity, so there is a need to better understand the importance of intraspecific variation to ecosystem-level processes. Tidal salt marshes are ideal ecosystems for investigating intraspecific variation in plant-nutrient relationships because they are dominated by a monoculture of the foundation species Spartina alterniflora, with distinct phenotypes that correspond to environmental gradients across the marsh. We conducted a field survey of existing …


Developing Motion Platform Dynamics For Studying Biomechanical Responses During Exercise For Human Spaceflight Applications, Kaitlin Lostroscio Mar 2018

Developing Motion Platform Dynamics For Studying Biomechanical Responses During Exercise For Human Spaceflight Applications, Kaitlin Lostroscio

USF Tampa Graduate Theses and Dissertations

In future human spaceflight missions, with prolonged exposure to microgravity, resistive and aerobic exercises will be countermeasures for bone loss, muscle loss, and decreased aerobic capacity. Two of the exercises of interest are squats and rowing. The cyclic forces produced during these exercises are at relatively low frequencies which are likely to excite structural resonances of space vehicles. Vibration Isolation Systems (VIS) are being designed to be paired with future exploration exercise devices in order to prevent these cyclic exercise forces from impacting the space vehicle. The VIS may be configured such that a platform supports the human and exercise …


Flames And Frogs – The Impact Of Environmental Disturbances On Host-Parasite Dynamics, Nicole Ortega Mar 2018

Flames And Frogs – The Impact Of Environmental Disturbances On Host-Parasite Dynamics, Nicole Ortega

USF Tampa Graduate Theses and Dissertations

The successful completion of this work is dedicated first to my grandparents for having always shown their unwavering love and encouragement in my journeys (most of which they kindly and politely only pretended to understand) and for having also served as life-long role models who upheld an unparalleled work ethic. To many whom I consider to be my chosen family, especially Ann Williams and Brittany Sears, who kept me laughing, but more importantly, kept my crazy train from derailing during these tumultuous years. To Wayne Price and Tom Jackman, who fostered the success of my career and are the epitome …


Strategies To Adjust For Response Bias In Clinical Trials: A Simulation Study, Victoria R. Swaidan Feb 2018

Strategies To Adjust For Response Bias In Clinical Trials: A Simulation Study, Victoria R. Swaidan

USF Tampa Graduate Theses and Dissertations

Background: Response bias can distort treatment effect estimates and inferences in clinical trials. Although prevention, quantification, and adjustments have been developed, current methods are not applicable when subject-level reliability is used as the measure of response bias. Thus, the objective of the current study is to develop, test, and recommend a series of bias correction strategies for use in these cases. Methods: Monte Carlo simulation and logistic regression modeling were used to develop the strategies, examining the collective impact of sample size (N), effect size (ES), reliability distribution, and response style on estimating the treatment effect size in a series …


Novel Role Of Histone Deacetylase 11 (Hdac11) In Regulating Normal And Malignant Hematopoiesis, Jie Chen Jan 2018

Novel Role Of Histone Deacetylase 11 (Hdac11) In Regulating Normal And Malignant Hematopoiesis, Jie Chen

USF Tampa Graduate Theses and Dissertations

During hematopoiesis, multilineage progenitor cells and the precursors are committed to individual hematopoietic lineages. In normal myelopoiesis, the immature myeloid cells (IMCs) differentiate into macrophages, neutrophils or dendritic cells. However, under tumor burden, these IMCs differentiate into myeloid derived suppressor cells (MDSCs) result in an up-regulation of immune suppressive factors and pro-tumor effect. The development of normal or malignant is tightly controlled by endogenous signals such as transcription factors and epigenetic regulations. HDAC11 is the newest identified members of the histone deacetylase (HDAC) family. Previous study in our group had identified HDAC11 as a negative regulator of interleukin 10 (IL-10) …


Perceptual And Physiologic Analysis Of Dystussia In Amyotrophic Lateral Sclerosis, Stephanie Anne Watts Dec 2017

Perceptual And Physiologic Analysis Of Dystussia In Amyotrophic Lateral Sclerosis, Stephanie Anne Watts

USF Tampa Graduate Theses and Dissertations

Swallowing and cough are two vital functions that are reflexive in nature and are related to each other in terms of shared neural and anatomical space. When a disorder impacts normal and effective swallowing and/or cough, the consequences can be life-threatening. Evaluation and treatment of swallowing and cough disorders can fall under the scope of practice of the speech-language pathologist and speech-language pathologists often are leading professionals. Furthermore, much of the current research on swallowing and cough is spearheaded by speech-language pathologists often working with a multi-disciplinary team. The focus of this dissertation is on the clinical evaluation of cough …


Astaxanthin Attenuates Mptp Induced Neurotoxicity And Modulates Cognitive Function In Aged Mice, Beth Grimmig Dec 2017

Astaxanthin Attenuates Mptp Induced Neurotoxicity And Modulates Cognitive Function In Aged Mice, Beth Grimmig

USF Tampa Graduate Theses and Dissertations

Parkinson’s disease is the second common neurodegenerative disease and is most frequently diagnosed in individuals over 60. There are no available medications that can prevent or restore the loss of neurons that correspond to motor impairments in patients. Identifying novel therapeutic compounds that are capable of slowing and reversing the extensive neurodegeneration that occurs in PD remains an important goal of the field. While basic research has identified potential therapeutic agents, studies often use young model organisms to demonstrate efficacy of the target compound. This approach ignores the impact of the aged CNS on the disease process, and likely contributes …


Spatial-Temporal Distribution Of Mosquito Larval Hot Spots In Papoli, Uganda: A Community-Based Approach To Mosquito Control, Ryan E. Tokarz Nov 2017

Spatial-Temporal Distribution Of Mosquito Larval Hot Spots In Papoli, Uganda: A Community-Based Approach To Mosquito Control, Ryan E. Tokarz

USF Tampa Graduate Theses and Dissertations

Mosquito species of the Anopheles gambaie complex are the predominant vectors of malaria transmission throughout sub-Saharan Africa. These mosquitoes tend to be endophilic, as well as anthropophilic, making them prime candidates for disease transmission. Within the same region, related mosquito vectors play a significant role in the transmission of additional human and zoonotic diseases. Furthermore, mosquito nuisance biting is an immense issue that cannot be ignored in terms of its impact on African communities. Depending on the respective factors involved, mosquito control programs throughout the continent have attempted to tackle these issues in a multitude of ways. This research approached …


Using Green Messages To Cue Recycling Tendencies, Danielle Quichocho Nov 2017

Using Green Messages To Cue Recycling Tendencies, Danielle Quichocho

USF Tampa Graduate Theses and Dissertations

Recycling of common plastics is a practical way to limit the amount of waste that ends up in landfills, and eventually contributes to various forms of pollution. However, statistics indicate that it is not currently a normalized, prioritized behavior. A pilot study indicated that relying only on preexisting frameworks such as the Elaboration Likelihood Model to understand consumer perceptions simply does not encompass the scope of the topic. Consumer experiences with green messages, especially in the current climate of a saturated advertising market are incredibly complex. Understanding these experiences is also currently being impeded by inconsistencies in how researchers in …


Ecological Epigenetics Of Avian Range Expansions, Holly J. Kilvitis Nov 2017

Ecological Epigenetics Of Avian Range Expansions, Holly J. Kilvitis

USF Tampa Graduate Theses and Dissertations

In light of human-mediated environmental change, a fundamental goal for biologists is to determine which phenotypic characteristics enable some individuals, populations or species to be more adept at coping with such change, while rendering others more vulnerable. Studying ongoing range expansions provide a unique opportunity to address this question by allowing documentation of how novel environments shape phenotypic variation on ecological timescales. At range-edges, individuals are exposed to strong selective pressures and population genetic challenges (e.g. bottlenecks and/or founder effects), which make genetic adaptation difficult. Nevertheless, certain species, such as the house sparrow (Passer domesticus), seem to thrive in their …


Hidden: A Case Study On Human Trafficking In Costa Rica, Timothy Adam Golob Nov 2017

Hidden: A Case Study On Human Trafficking In Costa Rica, Timothy Adam Golob

USF Tampa Graduate Theses and Dissertations

This is a case study on human trafficking that was conducted on the small Central American country of Costa Rica via a mixed-methods approach which included document review, surveys, and interviews. It was selected due to Costa Rica’s history of fluctuation between Tier 2 and Tier 2 Watch List status on the Trafficking in Persons Report, issued by the U.S. Department of State, over the last ten years. This ranking average indicates that it is one of the worst performing Central American states in efforts to combat trafficking in persons. This finding breaks with Costa Rica’s traditional placement as one …


Adverse Childhood Experiences And Its Association With Cognitive Impairment In Non- Patient Older Population, Mohini D. Dutt Nov 2017

Adverse Childhood Experiences And Its Association With Cognitive Impairment In Non- Patient Older Population, Mohini D. Dutt

USF Tampa Graduate Theses and Dissertations

This study explores cognitive impairment and its correlation to early- life adverse experiences in non-patient population between the ages of 50 to 65. This developmental approach and observational study design explores cognition in pre-clinical Alzheimer’s disease (AD). Using a standardized neuropsychological instrument, the Montreal Cognitive Assessment (MoCA) and clinically administered questionnaire, the ACE (Adverse Childhood Experiences), I hypothesized that participants with high ACE scores will inversely have low MoCA scores.

My goal was to use a multiple linear regression model with 3 covariates and 1 predictor of interest (ACEs). At 80% power, a sample size of 40 was calculated as …