Digital Commons Network^™

N-Acyl Ciprofloxacins: Synthesis, Antibacterial Activity And Effects On Molecular Loading Of Poly(Vinyl Benzoate) Nanoparticles, Ryan Cormier

USF Tampa Graduate Theses and Dissertations

Bacterial infections are becoming progressively more difficult to treat due to antibiotic resistance and the decreasing rate at which new antibiotics are brought to market. The Turos laboratory has attempted to tackle this problem for the last 15 years with the discovery of N-thiolated β-lactams leading to the design of polyacrylate nanoparticles to deliver these and other drugs. Chapter 1 discusses many reported instances of utilizing different types of polymeric nanoparticles to deliver antibiotics. Poly(lactic-co-glycolic acid) (PLGA), poly(alkyl cyanoacrylate) (PACA), poly(styrene-co-butylacrylate), and chitosan are the main polymers used to make nanoparticles. Chapter 2 describes the synthesis, antibacterial activity, and mechanism …

A Mother's Love: A Narrative Analysis Of Food Advertisements In An African American Targeted Women's Magazine, Janine Danielle Beahm

USF Tampa Graduate Theses and Dissertations

This thesis examines how food advertisers contributed to the cultural identity of the "good mother" in the 1990s and 2000s. It expands on previous research that investigated traditional gender ideologies in food advertisements by narrowing in on the specific stories presented to African American women. It highlights a time when advertisers were responding to the demands of African American activists to recognize the African American consumer, and depict African American characters in a positive light. A narrative method of inquiry is utilized to deconstruct the stories in 117 food advertisements running in Essence magazine (an African American targeted women's magazine) …

Production Of Bioactive Secondary Metabolites By Florida Harmful Bloom Dinoflagellates Karenia Brevis And Pyrodinium Bahamense, Cheska Burleson

USF Tampa Graduate Theses and Dissertations

Despite the critical role algae serve as primary producers, increases or accumulation of certain algae may result in Harmful Algal Blooms (HABs). Algal toxins from these blooms contribute significantly to incidences of food borne illness, and evidence suggests HABs are expanding in frequency and distribution. Mitigation of these HABs without knowledge of the ecological purpose and biochemical regulation of their toxins is highly unlikely. The production, function, and potential of secondary metabolites produced by the dinoflagellates Karenia brevis and Pyrodinium bahamense, were investigated.

Brevetoxins were demonstrated by two different methods to localize within the cytosol of Karenia brevis. …

Responsiveness Of The Federal Health System To The Needs Of 18-45 Year Old Adults With Physical Disabilities In Islamabad, Pakistan, Shaista Habibullah

USF Tampa Graduate Theses and Dissertations

Abstract

The health system has been defined as all people, institutions and resources that undertake actions with the primary intent of improving health, while responsiveness of the health system refers to its objective of responding to the legitimate expectations of the population it serves. Although responsiveness is a non-health objective of the health system, it affects the health status of the population by influencing treatment compliance, patient-provider communication and health services utilization. Furthermore, responsiveness has a fundamental value as it concerns basic human rights of the individuals being served by the health system.

This study was undertaken to determine how …

The Impact Of Arranging Music For The Large Ensemble On The Teacher: A Phenomenological Exploration, James Teodor Lindroth

USF Tampa Graduate Theses and Dissertations

Abstract

The purpose of this study was to examine the phenomenon of what arranging music in the large instrumental ensemble music setting came to mean to the teachers doing the arranging. Four secondary music teachers (N=4) were asked to create a musical arrangement for one of their school ensembles. Over a period of seven weeks, participants rehearsed their arrangement with their students. This study was guided by research on creative identity, the self, and various identity theories from the field of the social sciences. Data were collected by way of in depth semi-constructed interviews, field observations, and journals; and were …

The Walls Are Closing In: Comparing Property Crime Victimization Risk In Gated And Non-Gated Communities, Nicholas Branic

USF Tampa Graduate Theses and Dissertations

In recent years, a growing proportion of the population has moved into gated communities in response to an increasingly pandemic fear of crime. While a sizable body of research has addressed fear of crime and perceived safety in gated communities, few studies have investigated actual rates of victimization. The studies that do compare victimization in gated and non-gated communities tend to be localized assessments and present mixed findings on the effectiveness of community gating as a form of protection from crime.

The present study utilizes a cross-section of National Crime Victimization Survey data to investigate the micro-level effects of living …

Beliefs Of And Attitudes Toward Sexual Violence By A Diverse Group Of Self-Identified Male Collegiate Athletes, Belinda-Rose James

USF Tampa Graduate Theses and Dissertations

The objective of this research was to assess the beliefs of and attitudes towards sexual violence among self-identified male, undergraduate, athletes and non-athletes. Research has shown that there is an association between the subculture of athletics and the beliefs and attitudes towards sexual violence. Male, undergraduate, athletes have disproportionately been reported for sexual violence. This study examined common risk factors attributed to perpetration of sexual violence: rape myth acceptance, lower attitudes toward women, reactive aggression, and physical and verbal sexual coercion. Multiple-level risk factors were studied in order to acquire a comprehensive understanding of what possible associations between male collegiate …

"Free Your Mind . . . And The Rest Will Follow": A Secularly Contemplative Approach To Teaching High School English, Kendra Nicole Bryant

USF Tampa Graduate Theses and Dissertations

The purpose of my research is to provide high school English instructors and students a contemplative writing pedagogy that has the capacity to assist them in calming their bodies and quieting their minds so that they can focus their attention, openly explore self and others, rediscover their creativity, and reawaken their appreciation for the art of writing. Such a pedagogy is supported by mindfulness practices, which are exercises in moment-to-moment awareness that help to detach the practitioner from his or her thoughts. Mindfulness practices include breathing, walking, yoga, body scans, and visualizing; they provide quiet spaces wherein mind, body, and …

Butterbeer, Cauldron Cakes, And Fizzing Whizzbees: Food In J.K. Rowling's Harry Potter Series, Leisa Anne Clark

USF Tampa Graduate Theses and Dissertations

ABSTRACTThis thesis situates the Harry Potter books into the greater body of food studies and into the extant children's literary tradition through an examination of how food can be used to understand cultural identity. Food is a biological need, but because we have created social rules and rituals around food consumption and sharing, there is more to eating than simple nutritional value. The Harry Potter series is as much about overcoming childhood adversity, and good versus evil, as it is about magic, and food in the Harry Potter series is both abundant and relevant to the narrative, context, and themes …

The Role And Regulation Of Nsars: A Cell-Envelope Stress Sensing Two-Component System In Staphylococcus Aureus, Stacey Lynn Kolar

USF Tampa Graduate Theses and Dissertations

Abstract

S. aureus has 16 predicted two-component systems (TCS) that respond to a range of environmental stimuli, and allow for adaptation to stresses. Of these 16, three have no known function, and are not homologous to any other TCS found in closely related organisms. NsaRS is one such element, and belongs to the intramembrane-sensing histidine kinase (IM-HK) family, which is conserved within the Firmicutes. The regulators are defined by a small sensing domain within their histidine kinase, suggesting that they do not sense external signals, but stress in or at the membrane. Our characterization of NsaRS in this work reveals …

Women's Political Representation In Europe: An Analysis Of Structural And Attitudinal Factors, Jenna Elaine Mcculloch

USF Tampa Graduate Theses and Dissertations

In this mixed methods study, I explore the reasons for the low level of women in elected office in Europe. I analyze the impact of three structural factors (number of years since women's suffrage was enacted, type of electoral system, and presence of legal gender quotas) and three attitudinal factors (level of gender equality, percentage of female professionals, and level of religiosity) on the percentage of women in national legislatures in each of the European countries. Specifically, I pose the following research question: Which structural and/or attitudinal factors are more influential for women's political representation in European countries?

In order …

Sigma Factor N (Σn): A Novel Regulator Of Extreme Acid Resistance In Enterohemorrhagic E. Coli O157:H7, Pamela Ann Fay

USF Tampa Graduate Theses and Dissertations

Extreme acid resistance contributes to the successful transmission of enterohemorrhagic E. coli (EHEC) through acidic food matrices and the stomach, allowing it to gain access to the intestine and elicit disease in humans. Alternative sigma factor N (σ^N, encoded by rpoN) was previously identified as a novel regulator of extreme acid resistance in EHEC. This study investigated the role for σ^N and co-expressed products of the rpoN operon in the acid resistance phenotype of EHEC. The results revealed that σ^N primarily controls acid resistance through repression of the glutamate-dependent acid resistance (GDAR) system through control …

Patient Care Provider Safety: Examining One Intervention To Reduce Hospital Violence, Paul Leslie Ford

USF Tampa Graduate Theses and Dissertations

Abstract

In the summer of 2009, Tampa General care providers met with Hospital Administration to express concern that violence on care units was a growing problem and making it difficult to provide quality care. Nurses stated that such violence was one important reason many of their peers choose to retire. Administration took this situation seriously and formed a committee to gather information and submit suggestions to reduce the violence. The committee consisted of representatives from several nursing units, human resources, risk management, security, and administration. Duties assigned included investigation of the actual number of reports on all units and trends. …

An Evaluation Of The Implementation Of "The Happiest Toddler On The Block" Parenting Strategies By Young Mothers, Amye Elizabeth Bock

USF Tampa Graduate Theses and Dissertations

Young parents and their children are considered a high-risk population as they are more likely to lack social support networks, have limited access to opportunities to enhance parenting skills, and are often financially dependent. Young children whose mothers have poor parenting skills are more likely to have persistent problem behavior. Three young mothers living in a transitional housing facility participated in this study. The purpose of this study was to determine if these mothers could implement parenting strategies that are a part of a commercially available parenting book and DVD. This study found that: (1) mothers were able to correctly …

Learning Without Being Taught: A Look At How Schools, The Home And The Neighborhood Influence "Race" Conceptualization, Owen Christopher Gaither

USF Tampa Graduate Theses and Dissertations

ABSTRACT

Where do we get our ideas about the concept of `race'? The conceptualization of `race' has long been a topic of interest in the social sciences and society in general. The word `race' has been used and defined in different ways and different purposes throughout U.S. history. The definition of `race' therefore is arbitrary, changing according to the situation, but the consequences of how the word `race' is used are concrete and effect peoples lives daily. This research, in accord with much of the literature on the topic, shows that public schools play a major role in the conceptualization …

Investigation Into The Mechanism Of Salicylate-Associated Genotypic Antibiotic Resistance In Staphylococcus Aureus, Nada Salah Helal

USF Tampa Graduate Theses and Dissertations

Growth of Staphylococcus aureus with the NSAID salicylate increases phenotypic resistance (SAPAR), and the frequency at which heritable resistance occurs to various antibiotics (SAGAR). This study describes the effect of salicylate on heritable and phenotypic resistance to a set of antibiotics for laboratory and multi-drug resistant strains of S. aureus and investigates the link between resistance and SAGAR. Drug gradient plates were used to determine phenotypic resistance to antibiotics targeting DNA replication, transcription, translation and the cell wall in the presence or absence of salicylate. To measure heritable resistance, mutation frequencies were determined for each antibiotic in the presence and …

Toward A Working Theory Of Neurorhetorics, Jeffrey L. Honnold

USF Tampa Graduate Theses and Dissertations

This piece makes the claim that rhetoric is first philosophy--before philosophy, epistemology, ontology, or any other field--or that rhetoric is, at the least, on equal footing as these fields because:

empathy--and thusly the impulse for communication--is physiologically hardwired into humans; special distinctions between human and animal are largely artificial constructions, as is evidenced by neurosciences; "hard" science, in the form of neurosciences, is providing entrance points & opportunities for rhetoric to raise its status within the academy; and said neurosciences, in addition to empathy studies, have shown strong evidence supporting linguistic and evolutionary links between humans and other species, thereby …

On The Efficiency Of Us Equity Markets, Mikael Carl Erik Bergbrant

USF Tampa Graduate Theses and Dissertations

Most papers in empirical finance implicitly or explicitly assume the same price of risk, for each priced systematic risk factor, across all risky assets within a given domestic market. In doing so, they rely on the assumption that markets are domestically integrated and, as such, that the price of risk is determined independently of individual investors attitude towards risk. This is true in frictionless markets where investors have complete information, homogenous beliefs, and hold the mean-variance efficient combination of the market portfolio and a risk-free asset. However, investors might not hold the market portfolio because of exogenous reasons. In fact, …

A Cross-National Analysis Of The Human Papillomavirus, Sexually Transmitted Infections, And Sexual Behavior Among Men, Euna Marie August

USF Tampa Graduate Theses and Dissertations

There is a paucity of research on the risk for sexually transmitted infections (STIs) and sexual behavior among general populations of men. Research with male populations predominantly has focused on those subgroups considered to be at high risk of disease transmission, such as gay and bisexual men, injection drug users, and adolescents/young adults. Considerably fewer studies have examined factors among men, in general, and heterosexual men, specifically. Therefore, I conducted analyses with a cross-national sample of adult, sexually active men in Brazil, Mexico, and the United States to investigate sexual behaviors and risk factors associated with the human papillomavirus (HPV) …

Dissolved Inorganic Carbon Uptake In Thiomicrospira Crunogena Xcl–2 Is Atp–Sensitive And Enhances Rubisco–Mediated Carbon Fixation, Kristy Jae Menning

USF Tampa Graduate Theses and Dissertations

Many autotrophic organisms living in environments with episodically low dissolved inorganic carbon (DIC) concentrations compensate for these fluctuations by employing a carbon concentrating mechanism (CCM). By utilizing a CCM, these organisms can generate intracellular DIC concentrations much higher than extracellular, thereby providing sufficient substrate for carbon fixation. Carbon concentrating mechanisms have been well-studied in cyanobacteria but studies are lacking in other autotrophs. The gammaproteobacterium Thiomicrospira crunogena XCL-2 is a hydrothermal vent chemolithoautotroph that has a CCM, which is functionally similar to that of cyanobacteria. At hydrothermal vents, DIC concentrations and pH values fluctuate over time, with CO2 concentrations ranging from …

On The Design Of Socially-Aware Distributed Systems, Nicolas Kourtellis

USF Tampa Graduate Theses and Dissertations

Social media services and applications enable billions of users to share an unprecedented amount of social information, which is further augmented by location and collocation information from mobile phones, and can be aggregated to provide an accurate digital representation of the social world. This dissertation argues that extracted social knowledge from this wealth of information can be embedded in the design of novel distributed, socially-aware applications and services, consequently improving system response time, availability and resilience to attacks, and reducing system overhead. To support this thesis, two research avenues are explored.

First, this dissertation presents Prometheus, a socially-aware peer-to-peer service …

Perceived Firm Transparency: Scale And Model Development, Jennifer Dapko

USF Tampa Graduate Theses and Dissertations

In the last few years alone, calls for transparency by consumers have grown louder. No longer are consumers willing to sit back and allow firms to make `closed door' decisions that benefit the company (and its executives) at the expense of consumers and society. This dissertation begins to answer the call for a greater understanding of transparency from both practitioner and academic perspectives. In particular, this dissertation focuses on systematically developing a succinct definition of perceived firm transparency, developing a valid measure of transparency, and empirically testing antecedents and consequences of transparency.

Two studies were conducted to develop the transparency …

Fermentation And Supercritical Extraction Studies Of Açaí Berry, Rosanna Iris Ayala

USF Tampa Graduate Theses and Dissertations

The açaí berry has grown in popularity for dieters and the health conscious. The berry contains high levels of antioxidants. The main anthocyanins are cyanidin-3-rutinoside and cyanidin-3-glucoside. The berries also contain vitamins and nutrients that help boost energy and alertness, and fatty acids that help maintain normal cholesterol levels. As a result of the health benefits of the constituents, the berries are chosen for obtaining the active ingredients by extraction.

The solids left over after extraction still contain nutrients and useful components. There is a possibility of fermenting this residual and creating an açaí berry wine. Açaí berry wine is …

The Role Of Hsp70 In Cancer: A Study Of The Hsp70 / Akt Relationship, John Koren

USF Tampa Graduate Theses and Dissertations

The Hsp70 family of molecular chaperones is essential for

protein folding, re-folding misfolded client proteins, clearance

of aberrant client proteins, and can also inhibit programmed

cell death. There are two major cytosolic members of this

family: the constitutive Hsc70, and the inducible Hsp72. Under

stress conditions the Hsp70 family protects the cell from

protein related damage by the induction of Hsp72. Hsc70 and

Hsp72 are highly homologous with minor differences in

substrate binding. In cancers, Hsp72 is commonly induced and

this induction is thought to aid in cancer cell survival. In these

studies we demonstrate the differential regulation of the …

Expatriates' Acculturation Strategies: Going Beyond "How Adjusted Are You?" To "How Do You Adjust?", Matthew Lineberry

USF Tampa Graduate Theses and Dissertations

Expatriates' degree of adjustment to living and working in a foreign country is well-accepted as an important outcome variable in expatriate management research. However, measures of degree of adjustment do not capture the breadth of strategies expatriates may use to achieve such adjustment, which may be critical for understanding whether expatriates have achieved a healthy and productive orientation to life abroad. Borrowing from research on immigrant populations, this study examines the construct of expatriate acculturation strategies, which characterize expatriates' mode of adjustment along two independent dimensions reflecting maintenance of one's home culture and engagement of the host culture, respectively. One …

The Dark Circle: Spiritualism In Victorian And Neo-Victorian Fiction, Joseph Good

USF Tampa Graduate Theses and Dissertations

This dissertation offers critical and theoretical approaches for understanding depictions of Spiritualism in Victorian and Neo-Victorian fiction. Spiritualism has fascinated and repelled writers since the movement's inception in Hydesville, New York, in 1848, and continues to haunt writers even today. The conclusion of this dissertation follows Spiritualist fiction as it carries over into the Neo-Victorian genre, by discussing how themes and images of Victorian Spiritualism find "life after death" in contemporary work. Spiritualism, once confined to the realm of the arcane and academically obscure, has begun to attract critical attention as more scholars exhume the body of literature left behind …

An Exploration Of Undeclared Students' Expectations Of Experiences For Faculty Interactions And Co-Curricular Involvement, Lorie Anne Kittendorf

USF Tampa Graduate Theses and Dissertations

Student persistence and achievement are areas of significant concern for institutions of higher education. With national college graduation rates hovering in the 50% range, it is important for colleges and universities to understand which student characteristics and campus environments lead to greater success, as well as the expectations students have of the college experience.

Research on undeclared students is vast and dates back more than 70 years, and many of the seminal studies and respected research data have led to the perception that they are at higher risk of attrition and have lower levels of academic achievement than their declared …

What Propels Sexual Homicide Offenders? Testing An Integrated Theory Of Social Learning And Routine Activities Theories, Heng Choon Chan

USF Tampa Graduate Theses and Dissertations

Sexual homicide is a rare occurrence. Little is known about the offending perspective of sexual homicide from a criminological standpoint. Recently, Chan, Heide, and Beauregard (2011) proposed an integrative theoretical framework using concepts and propositions of Social Learning Theory (differential association, definitions, differential reinforcement or punishment, and imitation) and Routine Activities Theory (a motivated offender, an attractive and suitable target, and the absence of a capable guardian or guardianship) to elucidate the sexual homicide offending dynamics. According to this integrative model, the individual-level view of the sexual murderers is explained by …

From Immortal To Mortal: Objectification And Perceptions Of A Woman's Soul, Nathan A. Heflick

USF Tampa Graduate Theses and Dissertations

Abstract

Objectification most literally refers to perceiving a person as an object. Research shows that when people focus on a woman's appearance, compared to her personality, she is perceived of as more of an object (e.g., lower in human nature traits). These objectification effects, however, rarely occur for male targets. Moreover, humans, unlike objects, are typically believed to have a soul, that is, some part of the self that outlasts the death of the physical body and extends into a post-mortem existence (e.g., Heaven). In turn, I hypothesized that women, but not men, would be perceived as having less soul …

Functional Magnetic Nanoparticles, James Gass

USF Tampa Graduate Theses and Dissertations

Nanoparticle system research and characterization is the focal point of this research and dissertation. In the research presented here, magnetite, cobalt, and ferrite nanoparticle systems have been explored in regard to their magnetocaloric effect (MCE) properties, as well as for use in polymer composites. Both areas of study have potential applications across a wide variety of interdisciplinary fields.

Magnetite nanoparticles have been successfully dispersed in a polymer. The surface chemistry of the magnetic nanoparticle proves critical to obtaining a homogenous and well separated high density dispersion in PMMA. Theoretical studies found in the literature have indicated that surface interface energy …