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USF Tampa Graduate Theses and Dissertations

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An Assessment Of Elementary School Children’S Diet And Physical Activity Levels, Karen Tamara Serrano Arce Mar 2016

An Assessment Of Elementary School Children’S Diet And Physical Activity Levels, Karen Tamara Serrano Arce

USF Tampa Graduate Theses and Dissertations

With prevalence rates of obesity among children and adolescents steadily rising, childhood obesity and overweight has become a public health concern. Publically funded elementary schools are in a unique position to provide children with opportunities regarding the promotion of physical activity and healthy nutritional behaviors. Purpose: The purpose of this study was to conduct exploratory research to investigate the dietary habits of elementary school students enrolled in four Hillsborough County Out-of-School Time (HOST) care programs. Methods: The study utilized a quantitative, non-experimental study design. The instruments that were used in this research included a new questionnaire that was titled “All …


A Tourist Performance: Redefining The Tourist Attraction, Brandy Lee Kinkade Mar 2016

A Tourist Performance: Redefining The Tourist Attraction, Brandy Lee Kinkade

USF Tampa Graduate Theses and Dissertations

The aim of this paper is to examine the intersection of tourism and memoirs in the United States specifically how specific travel memoirs function as tourist attractions. This investigation employs performer-centered analysis as a method of inquiry in order to gain insight on tourist experience as well as concepts of travel, imagination and embodiment. The paper also employs MacCannell’s Semiotics of Attraction as a framework to illustrate the presence of the following categories: tourist, sight, and marker. The presence and the relationships established between these categories establish Into Thin Air and Almost Somewhere: Twenty-eight Days on the John Muir Trail …


Anti-Fat Attitudes And Weight Bias Internalization: An Investigation Of How Bmi Impacts Perceptions, Opinions And Attitudes, Laurie Schrider Mar 2016

Anti-Fat Attitudes And Weight Bias Internalization: An Investigation Of How Bmi Impacts Perceptions, Opinions And Attitudes, Laurie Schrider

USF Tampa Graduate Theses and Dissertations

Americans hold negative and judgmental attitudes towards obese and overweight individuals and these anti-fat attitudes and weight stigma have become a damaging form of discrimination. The internalization of weight bias and anti-fat attitudes contributes to negative health outcomes including: feelings of devalue, self-hate, anxiety, depression, body dissatisfaction and eating disturbances. The purpose of this study was to investigate weight bias internalization in individuals who perceive themselves as overweight as well as to examine differences in anti-fat attitudes among normal and overweight individuals. A sample of 202 male and females completed an online survey that assessed anti-fat attitudes via the Anti-Fat …


Effects Of Delay To Reinforcement On Selections For High-Tech And Low-Tech Leisure Items, Yuram Kim Mar 2016

Effects Of Delay To Reinforcement On Selections For High-Tech And Low-Tech Leisure Items, Yuram Kim

USF Tampa Graduate Theses and Dissertations

Many children are exposed to excessively technology. Such use of technology may lead to health issues including obesity, attention deficits, and sleep disorders. Research has shown that parameters of reinforcement, such as quality and delay, may influence how children allocate their preferences. One way to drive preference away from high-tech toys may be to arrange delays to reinforcement following such selections and immediate reinforcement for an alternative response. In Experiment 1, four subjects who preferred high-tech leisure items over low-tech leisure items were identified through the pair-stimulus preference assessments. The results of Experiment 2 indicated that all subjects were sensitive …


The Effect Of Exercise Order On Body Fat Loss During Concurrent Training, Tonya Lee Davis-Miller Mar 2016

The Effect Of Exercise Order On Body Fat Loss During Concurrent Training, Tonya Lee Davis-Miller

USF Tampa Graduate Theses and Dissertations

While the benefits of both cardiovascular exercise and resistance training have been well documented, there is a lack of evidence for the order of exercise that is most effective when both are done in the same day. This study was designed to look at two groups of participants performing both resistance (R) and cardiovascular (C) training in the same day to determine if their order, resistance before cardiovascular (R-C) or cardiovascular before resistance (C-R), matter with regard to changes in body composition, maximal strength, and maximal aerobic capacity. The participants were 17 women between the ages of 30 and 55 …


Assessment Of The Role Of Poly (Adp-Ribose) Polymerase In Drug-Induced Cardiomyopathy, Alexis I. Brinkerhoff Mar 2016

Assessment Of The Role Of Poly (Adp-Ribose) Polymerase In Drug-Induced Cardiomyopathy, Alexis I. Brinkerhoff

USF Tampa Graduate Theses and Dissertations

Drug-induced cardiotoxicity has resulted in a thorough evaluation of patient doses, treatments, and rehabilitation. One of the most commonly prescribed chemotherapeutic agents is cyclophosphamide. The active metabolite, acrolein, is one of the most potent inducers of cardiomyopathy. In this study, research was conducted on the H9c2 (2-1) cardiomyocyte cell line derived from the embryonic myocardium of rattus norvegicus to assess its competency for evaluation of the change in poly (ADP-ribose) polymerase (PARP) activity. The application of this model to study the effects of acrolein on PARP activation was chosen as an ideal determinant of cell damage produced by nitrogen mustards. …


“Even Five Years Ago This Would Have Been Impossible:” Health Care Providers’ Perspectives On Trans* Health Care, Richard S. Henry Mar 2016

“Even Five Years Ago This Would Have Been Impossible:” Health Care Providers’ Perspectives On Trans* Health Care, Richard S. Henry

USF Tampa Graduate Theses and Dissertations

Trans* studies and issues have recently increased in coverage by the media and popular press. With recent changes in the DSM-5 (APA, 2000; APA 2013) and insurance law (HHS, 2014), trans* healthcare has been under increasing scrutiny. While a small number of studies (Bradford, Reisener, Honnold, & Xavier, 2013; Grant et al., 2011; Rounds, McGrath, & Walsh, 2013; Tanner et al., 2014) have documented discrimination and lack of cultural competencies from the perspective of trans* patients, little research exists that examines the training, support, and decision-making processes of medical professionals who treat trans* patients (Snelgrove et al., 2012, p. 2). …


To Utopianize The Mundane: Sound And Image In Country Musicals, Siyuan Ma Mar 2016

To Utopianize The Mundane: Sound And Image In Country Musicals, Siyuan Ma

USF Tampa Graduate Theses and Dissertations

Many consider music, songs, and dance performance as utopian signifiers for cinema, but few has entered the utopian discourse of country musicals, a small genre of cinema usually known as country music films. By closely scrutinizing Pure Country (1992), this thesis aims to reveal how country music—as music numbers and as background cues— integrate and connect the fragmented on-screen world for the country musicals so as to offer audiences a fullness of utopian experience, and how this utopian effect are culturally significant for American audiences due to country music’s unique mechanism of constructing utopia and nostalgia in its past-orientations, sentimentalities, …


Concerns Of Water Scarcity And Water Quality Among Two Andean Communities In Peru, Kelsey Anne Anderson Mar 2016

Concerns Of Water Scarcity And Water Quality Among Two Andean Communities In Peru, Kelsey Anne Anderson

USF Tampa Graduate Theses and Dissertations

This thesis sought to explore the perceptions and experiences of Andean women regarding water quality, water scarcity, and health among two communities in Carhuaz province of Ancash, Peru. Household surveys (n=25), semi-structured interviews (n=10), unstructured interviews (n=2), and participant observation were conducted with local women to investigate their concerns and perceptions of water and health. An additional two unstructured interviews were conducted with a local water authority and doctor in order gain another perspective on the issues of water security and health.

The pressure of a changing climate and of a problematic water governance system in Andean Peru create an …


Constructing The West: The Hired Hand And Mccabe & Mrs. Miller And The Challenge Of Public Space, Eric Ward Ross Mar 2016

Constructing The West: The Hired Hand And Mccabe & Mrs. Miller And The Challenge Of Public Space, Eric Ward Ross

USF Tampa Graduate Theses and Dissertations

The Western has been an important and iconic part of American culture since the opening of the frontier. However, very few scholars have looked closely at the way the genre constructs the past through public and private spaces like frontier towns and settlements.

The 1971 films, The Hired Hand and McCabe & Mrs. Miller are two texts that revitalized, and in the process revised, the Western genre in the early 1970s. My paper examines the ways in which conflicts between public and private spaces in the films reflect the social and cultural conflicts in America at the time. Both films …


"But Our Hands Are Tied": Assessing School Gardening Efforts At Title I Elementary Schools In Pinellas County, Florida, Alexandra Grace Lancey Mar 2016

"But Our Hands Are Tied": Assessing School Gardening Efforts At Title I Elementary Schools In Pinellas County, Florida, Alexandra Grace Lancey

USF Tampa Graduate Theses and Dissertations

This research was designed to understand current school gardening efforts in Pinellas County, Florida. School gardens have become an important aspect of experiential learning and nutrition education in schools throughout the United States. Many not-for-profit organizations have attempted to increase the prevalence and efficacy of school garden programs as a means of providing educational opportunities and working to curb diet-related health issues in children. Most of these organizations are seen as apolitical in nature, because they access mainly private sector funding sources and volunteer support. This provides flexibility for these social projects, but also takes pressure off of the state …


Avatar Self-Identification, Self-Esteem, And Perceived Social Capital In The Real World: A Study Of World Of Warcraft Players And Their Avatars, Melissa Watts Mar 2016

Avatar Self-Identification, Self-Esteem, And Perceived Social Capital In The Real World: A Study Of World Of Warcraft Players And Their Avatars, Melissa Watts

USF Tampa Graduate Theses and Dissertations

This study explored the relationship between people who play massively multiplayer online roleplaying games (MMORPGs) and their avatars, as well as the impact on players’ self-esteem and perceived social capital in the real world. To examine these influences of online video gameplay, this research investigated gamers who play the popular MMORPG, World of Warcraft (WoW). This study employed an online survey made available on Reddit, a widely-used news, entertainment, and social-networking website, in which all the content is user-generated. The research questionnaire was intended to reveal the bond between MMORPG players and their avatars; the study examined how this relationship …


Modeling The Extent Of Virus Removal In Waste Stabilization Ponds To Support Reuse Of Wastewater, Kelly James Vannoy Mar 2016

Modeling The Extent Of Virus Removal In Waste Stabilization Ponds To Support Reuse Of Wastewater, Kelly James Vannoy

USF Tampa Graduate Theses and Dissertations

Waste stabilization ponds (WSPs) are one of the most prevalent types of domestic wastewater treatment technologies employed worldwide, and global stressors such as urbanization, population growth, climate change, and water scarcity have increased the demand for reusing treated wastewater. The safe reuse of treated wastewater in agriculture can ease water scarcity, aid in food production, and reduce environmental degradation from the discharge of wastewater effluent to surface waters. The ability to predict virus concentrations in wastewater effluent is an important criterion for determining whether wastewater is suitable for discharge to the environment or for reuse in agriculture. However, many uncertainties …


Investigating Alternative Subsistence Strategies Among The Homeless Near Tampa, Florida, Matthew Peter Rooney Mar 2016

Investigating Alternative Subsistence Strategies Among The Homeless Near Tampa, Florida, Matthew Peter Rooney

USF Tampa Graduate Theses and Dissertations

Modern homelessness is one of the most pressing social and political problems of our time. Several hundred thousand people experience homelessness in the United States each year, and the U.S. Department of Housing, which attempts to count those people, has admitted that their statistics are conservative estimates at best. A recent archaeological study (Zimmerman et al 2010) examining material culture associated with homeless communities in Indianapolis has suggested that those who are considered chronically homeless have generally abandoned wage labor and are instead pursuing urban foraging as a subsistence strategy. In order to better understand the structures of homeless communities, …


Exciton Dynamics And Many Body Interactions In Layered Semiconducting Materials Revealed With Non-Linear Coherent Spectroscopy, Prasenjit Dey Mar 2016

Exciton Dynamics And Many Body Interactions In Layered Semiconducting Materials Revealed With Non-Linear Coherent Spectroscopy, Prasenjit Dey

USF Tampa Graduate Theses and Dissertations

Atomically thin, semiconducting transition metal dichalogenides (TMDs), a special class of layered semiconductors, that can be shaped as a perfect two dimensional material, have garnered a lot of attention owing to their fascinating electronic properties which are achievable at the extreme nanoscale. In contrast to graphene, the most celebrated two-dimensional (2D) material thus far; TMDs exhibit a direct band gap in the monolayer regime. The presence of a non-zero bandgap along with the broken inversion symmetry in the monolayer limit brands semiconducting TMDs as the perfect candidate for future optoelectronic and valleytronics-based device application. These remarkable discoveries demand exploration of …


Factors Associated With Sexually Transmitted Infections (Stis) And Multiple Sti Co-Infections: Results From The Evri Hiv Prevention Preparedness Trial, Ubin Pokharel Mar 2016

Factors Associated With Sexually Transmitted Infections (Stis) And Multiple Sti Co-Infections: Results From The Evri Hiv Prevention Preparedness Trial, Ubin Pokharel

USF Tampa Graduate Theses and Dissertations

Objective: The objective of this study was to describe the prevalence of sexually transmitted co-infections and assess factors associated with a single infection and co-infections.

Methods: A total of 388 women were included in this study. At enrollment of the EVRI trial women were tested for five STIs: Human papilloma virus (HPV), Chlamydia trachomatis, Neisseria gonorrhoeae, Herpes simplex virus-2 (HSV-2) and Treponema pallidum. Prevalence of STI infections and proportion of women with different combinations of co-infections were calculated. Factors associated with single infection and STI co-infection were assessed using a polytomous logistic regression model and odds ratio …


Incidence, Persistence, And Recurrence Of Anogenital Α- Mucosal Hpv Infections (Hpv 6, 11, 16, 18, 31, 33, 45, 52 And 58), Shitaldas J. Pamnani Mar 2016

Incidence, Persistence, And Recurrence Of Anogenital Α- Mucosal Hpv Infections (Hpv 6, 11, 16, 18, 31, 33, 45, 52 And 58), Shitaldas J. Pamnani

USF Tampa Graduate Theses and Dissertations

Objectives: The aims of this study were to: 1) Assess whether naturally induced anti-HPV antibodies are associated with subsequent acquisition of genital HPV 6, 11, 16, and 18 infections in men, 2) assess the recurrence (redetection) of genital HPV infections of the 9-valent vaccine HPV types and investigate factors associated with recurrent infections among men, and 3) assess the risk of type-specific sequential acquisition of anal HPV infection following a genital HPV infection of the 9-valent vaccine HPV types among men who have sex with women (MSW).

Methods: 4,123 healthy men were followed every six months (median follow-up time 4.1 …


In Search Of Solidarity: Identification Participation In Virtual Fan Communities, Jaime Shamado Robb Mar 2016

In Search Of Solidarity: Identification Participation In Virtual Fan Communities, Jaime Shamado Robb

USF Tampa Graduate Theses and Dissertations

This study questions the way sports fans create (a sense of) community through online conversations. Here, ‘community’ and ‘internet’ are seen as invitational terms that suggest an authentic social interaction. By examining the language used by fans to sustain a sense of solidarity in the virtual realm, this study questions the ways in which rhetoric frames the situation. Participation in the virtual space relies on practices of identification derived from physical engagements. By using a rhetorical approach, this study illuminates the way individual participants operationalize a rhetoric in virtual conversations that spiritualize the fan’s experience at the base of a …


Selective Enhancement Of Macropinocytosis For The Treatment Of Non-Small Cell Lung Cancer, Raul Iglesias Mar 2016

Selective Enhancement Of Macropinocytosis For The Treatment Of Non-Small Cell Lung Cancer, Raul Iglesias

USF Tampa Graduate Theses and Dissertations

Over the past few years, researchers have focused their attention on the development of targeted cancer therapies to minimize the side effects associated with non-targeted treatments such as chemotherapy. Specifically, these approaches have focused on blocking growth factor receptors (GFR) that are overexpressed in cancer cells. In this thesis, we also focus on targeting overexpressed GFR; however, instead of blocking the GFR, our novel approach aims at using them to selectively enhance the endocytotic process of macropinocytosis to deliver peptides that either disrupts the mitochondria or inhibits glycolysis.

Herein, we show the selective enhancement of macropinocytosis by the fusion protein …


Preparation, Change, Retirement, And Future Challenge: The Leadership Experience Of Former Florida College System Presidents, Kevin O'Farrell Mar 2016

Preparation, Change, Retirement, And Future Challenge: The Leadership Experience Of Former Florida College System Presidents, Kevin O'Farrell

USF Tampa Graduate Theses and Dissertations

A leadership emergency is developing in higher education. According the American Association for Community Colleges, by 2022, 75% of current community college presidents intend to retire, and within five years an additional 15% will exit the presidency. As these individuals leave their leadership role, the higher education environment they leave behind will change. Understanding this impending leadership crisis, the purpose of this qualitative interview study was to describe and understand the leadership experience of former Florida College System institution presidents, their perspective and reflection on the institution of the presidency and its evolution, and their thoughts regarding the pertinent challenges …


Production Of Biodiesel From Soybean Oil Using Supercritical Methanol, Shriyash Rajendra Deshpande Mar 2016

Production Of Biodiesel From Soybean Oil Using Supercritical Methanol, Shriyash Rajendra Deshpande

USF Tampa Graduate Theses and Dissertations

The slow yet steady expansion of the global economies, has led to an increased demand for energy and fuel, which would eventually lead to shortage of fossil fuel resources in the near future. Consequently, researchers have been investigating other fuels like biodiesel. Biodiesel refers to the monoalkyl esters which can be derived from a wide range of sources like vegetable oils, animal fats, algae lipids and waste greases. Currently, biodiesel is largely produced by the conventional route, using an acid, a base or an enzyme catalyst. Drawbacks associated with this route result in higher production costs and longer processing times. …


“It’S Not Like A Movie. It’S Not Hollywood:” Competing Narratives Of A Youth Mentoring Organization, Carley Geiss Mar 2016

“It’S Not Like A Movie. It’S Not Hollywood:” Competing Narratives Of A Youth Mentoring Organization, Carley Geiss

USF Tampa Graduate Theses and Dissertations

Direct social service workers face a variety of difficulties including low pay, limited upward mobility, role ambiguity, and emotional exhaustion. This study adds to the understanding of the complexities of front-line service work with an analysis of the storytelling of case managers working with Big Brothers Big Sisters. Interview participants describe a problem of “volunteer expectations,” which they define as related to the organizational storytelling of the program: the images that entice people to volunteer do not match actual volunteer experiences. I argue that glamorized storytelling through marketing and recruitment tactics creates unintended, negative consequences for volunteers and case managers. …


Science, Policy, And Decision Making: A Case Study Of Deliberative Rhetoric And Policymaking For Coastal Adaptation In Southeast Florida, Karen Patricia Langbehn Mar 2016

Science, Policy, And Decision Making: A Case Study Of Deliberative Rhetoric And Policymaking For Coastal Adaptation In Southeast Florida, Karen Patricia Langbehn

USF Tampa Graduate Theses and Dissertations

The purpose of this study was to observe and analyze the process of regional climate adaptation planning and the role of stakeholder deliberation in decision making about adaptation actions. It employed a case study approach based on one of three total study sites of an international, multidisciplinary grant titled, “METROPOLE: An Integrated Framework to Analyze Local Decision Making and Adaptive Capacity to Large-Scale Environmental Change”. The purpose of the case study of this project was to analyze stakeholder deliberation at two workshops at the grant’s Broward County, Florida site regarding two adaptation options: elevation/floodproofing and voluntary buyouts. Analyzing stakeholder deliberation …


"I'M Not Broken": Perspectives Of Students With Disabilities On Identity-Making And Social Inclusion On A College Campus, Melinda Leigh Maconi Mar 2016

"I'M Not Broken": Perspectives Of Students With Disabilities On Identity-Making And Social Inclusion On A College Campus, Melinda Leigh Maconi

USF Tampa Graduate Theses and Dissertations

Narratives help individuals to make sense of their lives and their everyday worlds. Within these narratives, individuals make sense of identities. Historically, people with disabilities have been depicted as helpless victims of their own bodies. However, during the twentieth century, disability rights social movements constructed a counter-narrative, stating that society’s reactions to different bodies was the real source of disability. While this was a positive status change for people with disabilities, it did not do enough to shed the status as victim. Yet many students with disabilities do not see themselves as victims. Therefore, I used narrative analysis to answer …


Containment: A Failed American Foreign Policy And How The Truman Doctrine Led To The Rise In Islamic Extremism In The Muslim World, Christopher Jonathan Gerber Mar 2016

Containment: A Failed American Foreign Policy And How The Truman Doctrine Led To The Rise In Islamic Extremism In The Muslim World, Christopher Jonathan Gerber

USF Tampa Graduate Theses and Dissertations

After World War II the United States, faced with the new Soviet threat of Communism, instituted the foreign policy known as “containment” in order to mitigate the threat to Western European states of Soviet expansionism. After the fall of Communism in the USSR in 1991 that policy was deemed, at once, a success and an anachronism. The power vacuum that the subsequent abandonment of that policy created was most notable in the Islamic states that had served as proxies in the Cold War against Communism. Both the backdrop of containment as well as the withdrawal of that policy served to …


Elastin Like Polypeptides As Drug Delivery Vehicles In Regenerative Medicine Applications, Alex Leonard Mar 2016

Elastin Like Polypeptides As Drug Delivery Vehicles In Regenerative Medicine Applications, Alex Leonard

USF Tampa Graduate Theses and Dissertations

Elastin like polypeptides (ELPs) are a class of naturally derived biomaterials that are non-immunogenic, genetically encodable, and biocompatible making them ideal for a variety of biomedical applications, ranging from drug delivery to tissue engineering. Also, ELPs undergo temperature-mediated inverse phase transitioning, which allows them to be purified in a relatively simple manner from bacterial expression hosts. Being able to genetically encode ELPs allows for the incorporation of bioactive peptides and functionalization of ELPs. This work utilizes ELPs for regenerative medicine and drug delivery.

The goal of the first study was to synthesize a biologically active epidermal growth factor-ELP (EGF-ELP) fusion …


Modeling Food Security, Energy, And Climate And Cultural Impacts Of A Process: The Case Study Of Shea Butter In Sub-Saharan Africa, Colleen Claire Naughton Feb 2016

Modeling Food Security, Energy, And Climate And Cultural Impacts Of A Process: The Case Study Of Shea Butter In Sub-Saharan Africa, Colleen Claire Naughton

USF Tampa Graduate Theses and Dissertations

Millions of people in the world, particularly women and people in sub-Saharan Africa, suffer from hunger and poverty. Three of the major 2015-2030 United Nation’s Sustainable Development Goals (SDGs) aim to eliminate hunger through food security and sustainable agriculture, eradicate poverty, and achieve gender equality through women’s empowerment. Shea trees and their associated fruit and butter can play a major role in each of these three SDGs for women and their families throughout sub-Saharan Africa. Shea trees are located over a wide expanse stretching more than 5,000 kilometers across over eighteen countries in sub-Saharan Africa. These trees produce fruit that …


Population Dynamics And Vulnerability Reduction: The Role Of Non-Profit Organizations Following The 2011 Earthquake In Christchurch, New Zealand, Nicole Suzanne Hutton Feb 2016

Population Dynamics And Vulnerability Reduction: The Role Of Non-Profit Organizations Following The 2011 Earthquake In Christchurch, New Zealand, Nicole Suzanne Hutton

USF Tampa Graduate Theses and Dissertations

With the adoption of neo-liberal policies and the decline in social welfare, non-profit organizations have been increasingly integrated into public service provision. Such changes raise questions regarding formal policies and access for marginalized populations, no more so than in disaster settings as formal disaster management of sexual health services are still vague. This study identifies the role of non-profit organizations in providing public health and social services through the lens of sexual health commitments following the September 2010 Darfield Earthquake and subsequent major aftershock during February 2011 in Christchurch, New Zealand. The primary goals of this study were three fold, …


Dialectical Behavior Therapy In College Counseling Centers: Practical Applications And Theoretical Considerations, Carla Chugani Dec 2015

Dialectical Behavior Therapy In College Counseling Centers: Practical Applications And Theoretical Considerations, Carla Chugani

USF Tampa Graduate Theses and Dissertations

Authors over the last two decades have discussed the myriad of challenges present in managing college students with severe mental health disorders. During the same time period, Marsha Linehan developed dialectical behavior therapy (DBT) as an empirically sound intervention for individuals with suicidal and self-injurious behaviors and this treatment grew to be an evidence-based practice for a range of challenging clinical issues. I argue that one solution to continued increases in college students who present for treatment to their college counseling centers with difficult-to-treat mental health issues, including but not limited to, borderline personality disorder (BPD), is to implement DBT …


Synthesis Of Agents For The Treatment And Analysis Of Tropical Diseases, Jeanine Yacoub Nov 2015

Synthesis Of Agents For The Treatment And Analysis Of Tropical Diseases, Jeanine Yacoub

USF Tampa Graduate Theses and Dissertations

Toxoplasmosis is an opportunistic disease caused by the protozoan parasite Toxoplasma gondii. The parasite is usually staved off by a healthy immune system and remains dormant in the body. In immunocompromised patients, the parasite can become active and spread throughout the body causing symptoms such as encephalitis, cognitive disorders, seizures, and death. Combination drug therapy is the usual treatment for toxoplasmosis; however, patients suffer from problems of intolerance, allergic reactions, and cytotoxicity. In an effort to identify new drug targets for toxoplasmosis, a series of compounds have been synthesized that can be used as tools to probe the unique …