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USF Tampa Graduate Theses and Dissertations

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Exploring The Effects Of Bmi Health Report Card Letters Among 6Th Grade Students And Parents: An Application Of The Social Cognitive Theory, Jenna M. Kaczmarski Nov 2009

Exploring The Effects Of Bmi Health Report Card Letters Among 6Th Grade Students And Parents: An Application Of The Social Cognitive Theory, Jenna M. Kaczmarski

USF Tampa Graduate Theses and Dissertations

In response to the growing child and adolescent obesity epidemic, some states and local school authorities are mandating the measurement of Body Mass Index (BMI). However, there is limited research addressing whether schools are an appropriate setting and the intended as well as unintended effects of sharing this information with parents. Furthermore, there is yet to be conclusive evidence that shows that BMI screening in the school setting is an effective way to improve student BMI status. Therefore, the purpose of this research study was to explore the effects of BMI Health Report Card Letters among 6th grade students and …


Latent Newspaper Functions During The Impact Phase Of Hurricane Katrina, Christina A. Brown Nov 2009

Latent Newspaper Functions During The Impact Phase Of Hurricane Katrina, Christina A. Brown

USF Tampa Graduate Theses and Dissertations

Media is used by audiences for more than its simple role as information provider. Audiences have been found to use news providers output in a multitude of ways. It has been found that some audience members have used such output as a way to gain social capital that aids in the generation of feelings of social cohesion with their community. This has been found to be especially true during the impact phase of a natural disaster, such as a hurricane (Perez-Lugo, 2004). Unfortunately what news providers specifically articulate that might have this latent use by audiences has not been studied …


Gender And Internal Migration In Wuhan, Hubei Province, China: Rural Hometowns, Factory Work, And Urban Experiences, Milena Urszula Janiec-Grygo Nov 2009

Gender And Internal Migration In Wuhan, Hubei Province, China: Rural Hometowns, Factory Work, And Urban Experiences, Milena Urszula Janiec-Grygo

USF Tampa Graduate Theses and Dissertations

This thesis focuses on gender and scale as key aspects of the rural-to-urban migration process in China. Its specific aim is to connect economic and social reasons for rural women's migration towards urban factory work. Contemporary large-scale migration studies show inconsistencies and contradictions concerning reasons for migration, especially as it relates to gender. Thus, migration research often emphasizes the positive social changes experienced by women workers, in effect signaling that the most important needs of women migrants can be satisfied without economic gains. In contrast, the proposed study seeks to show that social and economic reasons intertwine within women's experiences …


Developing Pre-Literacy Skills In Preschool Children: The Utilization Of Parents As A Vital Resource, Ashley N. Sundman Nov 2009

Developing Pre-Literacy Skills In Preschool Children: The Utilization Of Parents As A Vital Resource, Ashley N. Sundman

USF Tampa Graduate Theses and Dissertations

This study examined the effects of a parent-implemented intervention on preschool children's development of letter-naming and phonological awareness skills. Six parent-child dyads with children enrolled in a Head Start Program in West Central Florida were selected to participate in the study. A multiple baseline across participants design was used to evaluate the impact of an intervention package that included activities focusing on: (1) using mnemonics to learn letter names and (2) developing phonological awareness of the onsets of words through parent questioning and feedback. Phonological awareness development was measured using the Dynamic Indicators of Basic Early Literacy Skills First Sound …


Leading Change In Schools: Leadership Practices For A District Supported School-Based Reform Model, Monica C. Verra Nov 2009

Leading Change In Schools: Leadership Practices For A District Supported School-Based Reform Model, Monica C. Verra

USF Tampa Graduate Theses and Dissertations

The reauthorization of the Individual with Disabilities Education Act of 2004 strongly encourages the use of a response-to-intervention (RtI) model to reduce the number of students identified as learning disabled, to increase student achievement, and to close learning gaps between subgroups of students. RtI is based on the systematic assessment of students' responses to high-quality research-based instruction and interventions. The implementation of a research-based school-specific intervention model, such as RtI, may result in significant change for schools and districts.

The purpose of this study was to describe perceptions of the level of change the implementation of RtI represents in a …


Mathematics Education: The Voice Of African American And White Adolescents, Sharondrea R. King Nov 2009

Mathematics Education: The Voice Of African American And White Adolescents, Sharondrea R. King

USF Tampa Graduate Theses and Dissertations

Several studies have provided evidence regarding factors that contribute to the mathematics achievement gap between African American and White students. Byrnes (2003) found that 45%-50% of the difference in White and African American students' performance in mathematics was associated with socioeconomic status, exposure to learning opportunities, and motivational aspects of math while 4.5% was explained by ethnicity. The goal in this mixed method study was to examine the mathematics attitude of African American (n = 22) and White (n = 10) high school students and to allow students to voice what practices and supports they perceived enabled them to learn …


Tracing Anthropogenic Wastes: Detection Of Fluorescent Optical Brighteners In A Gradient Of Natural Organic Matter Fluorescence, Laura Kellie Dixon Nov 2009

Tracing Anthropogenic Wastes: Detection Of Fluorescent Optical Brighteners In A Gradient Of Natural Organic Matter Fluorescence, Laura Kellie Dixon

USF Tampa Graduate Theses and Dissertations

A dual wavelength method was developed for the field detection of optical brighteners

(OBs), fluorescent laundry additives used as indicators of anthropogenic wastes. The

method was quantitative for OBs under variable levels of fluorescent colored dissolved

organic matter (CDOM). Based on excitation at 300-400 nm and 440 and 550 nm

emission, the method assumed a constant ratio of fluorescence due to CDOM alone, even

if absolute amplitude varied. Concentrations of OBs were computed as the difference

between the observed 440 nm emission and the expected CDOM fluorescence at 440 nm,

as extrapolated from the 550 nm fluorescence and established CDOM …


Determinants Of Nutrition Appointment Non-Attendance Among Male Veterans, Claire Fontenot Bell Nov 2009

Determinants Of Nutrition Appointment Non-Attendance Among Male Veterans, Claire Fontenot Bell

USF Tampa Graduate Theses and Dissertations

During fiscal years 2006 and 2007, nearly 1 in 4 Veterans failed to keep their individual nutrition appointments, impeding clinic workflow, productivity, and management of weight and nutrition related health conditions. The purpose of this study was to identify determinants of nutrition appointment attendance in the Veteran population. This study examined the cognitive and structural factors that influence nutrition appointment attendance. Specifically, the study sought to determine: Veteran reported reasons for non-attendance and factors associated with appointment attendance. The research design entailed sequential use of qualitative and quantitative methods. Individual, semi-structured interviews and a mail survey were used to identify …


Effects Of Expectancies And Coping On Pain-Induced Motivation To Smoke, Joseph W. Ditre Nov 2009

Effects Of Expectancies And Coping On Pain-Induced Motivation To Smoke, Joseph W. Ditre

USF Tampa Graduate Theses and Dissertations

The prevalence of tobacco smoking among persons with recurrent pain is approximately twice that observed in the general population. Smoking has been associated with the development and exacerbation of several chronically painful conditions. Conversely, there is both experimental and cross-sectional evidence that pain is a potent motivator of smoking. A recent study provided the first evidence that laboratory-induced pain could elicit increased craving and produce shorter latencies to smoke (Ditre & Brandon, 2008). To further elucidate interrelations between pain and smoking, and to identify potential targets for intervention, the current study tested whether several constructs derived from social-cognitive theory influence …


The Influence Of Perceived Social Support From Parents, Classmates, And Teachers On Early Adolescents’ Mental Health, Tiffany N. White Nov 2009

The Influence Of Perceived Social Support From Parents, Classmates, And Teachers On Early Adolescents’ Mental Health, Tiffany N. White

USF Tampa Graduate Theses and Dissertations

The present study examined the relationships among perceived social support, mental health, and achievement in early adolescents, via analysis of an archival data set consisting of 390 middle school students. Specifically of interest was how various sources of social support (i.e., parent, classmate, and teacher) independently and uniquely predicted pathology (i.e., internalizing and externalizing symptoms) and wellness (i.e., life satisfaction) in youth. This study also examined the role of gender in the relationship between social support and mental health outcomes in order to delineate the specific types of support most salient to boys versus girls. Finally, this study explored the …


The Development Of A Human Polyomavirus Quantitative Pcr Assay To Assess Viral Persistence, Water Quality, And Human Health Risks, Shannon M. Mcquaig Nov 2009

The Development Of A Human Polyomavirus Quantitative Pcr Assay To Assess Viral Persistence, Water Quality, And Human Health Risks, Shannon M. Mcquaig

USF Tampa Graduate Theses and Dissertations

Microbial water quality is generally assessed using fecal indictor organisms; however host-specific microbial source tracking (MST) methodologies can be employed to differentiate sources of fecal pollution. The central goal of this research was to develop and validate a QPCR assay for the quantification of two human-specific polyomaviruses (HPyVs) in environmental water samples. These viruses are prevalent worldwide and produce lifelong, asymptomatic viruria in immunocompetent individuals.

A Taqman® quantitative PCR (QPCR) assay based on the conserved T-antigen of two HPyVs (JCV and BKV) was developed and optimized (Chapter 2). HPyVs were detected in a high proportion of human-associated waste samples (e.g. …


Globalization, Migration And The U.S. Labor Market For Physicians: The Impact Of Immigration On Local Wages, Finnie B. Cook Nov 2009

Globalization, Migration And The U.S. Labor Market For Physicians: The Impact Of Immigration On Local Wages, Finnie B. Cook

USF Tampa Graduate Theses and Dissertations

The healthcare labor market has experienced some significant changes in the last half century, including the establishment of Medicare and Medicaid in 1965, the emergence of managed care in the 1980s, and the worldwide mobility of labor encouraged by globalization. Currently, more than 25% of physicians working in the U.S. are foreign-born. The existing body of literature related to the impact of immigration on local wages has to date found conflicting results. The purpose of this research is to evaluate the impact of immigration of foreign physicians on local physician wages. This study employs physician survey data from the AMA …


Task Oriented Simulation And Control Of A Wheelchair Mounted Robotic Arm, Fabian Farelo Nov 2009

Task Oriented Simulation And Control Of A Wheelchair Mounted Robotic Arm, Fabian Farelo

USF Tampa Graduate Theses and Dissertations

The main objective of my research is to improve the control structure for the new Wheelchair Mounted Robotic Arm (WMRA) to include new algorithms for optimized task execution; that is, making the WMRA a modular task oriented mobile manipulator. The main criterion to be optimized is the fashion in which the wheelchair approaches a final target as well as the starting and final orientation of the wheelchair. This is a novel approach in non-holonomic wheeled manipulators that will help in autonomously executing complex activities of daily living (ADL) tasks.

The WMRA is a 9 degree of freedom system, which provides …


Effects Of Geomorphic Setting On Shallow-Groundwater Exchange And Water Temperature Of Salmon-Bearing Headwater Streams Of The Lower Kenai Peninsula, Alaska, Jason C. Bellino Nov 2009

Effects Of Geomorphic Setting On Shallow-Groundwater Exchange And Water Temperature Of Salmon-Bearing Headwater Streams Of The Lower Kenai Peninsula, Alaska, Jason C. Bellino

USF Tampa Graduate Theses and Dissertations

Temperature is an important physical characteristic of headwater streams that controls the presence and health of juvenile salmonids. Surface water temperature is controlled by many factors including exchanges with groundwater. A study of the hydrology of wetlands associated with headwater streams on the Lower Kenai Peninsula was conducted to determine the effect of geomorphic setting on groundwater discharge to streams and ultimately on in-stream water temperature. Attention was focused on drainage-way and discharge slope wetlands as two end-members of the geomorphic settings of the study area.

Data were collected at 18 study reaches spanning four major watersheds in the study …


Microbial Population Analysis In Leachate From Simulated Solid Waste Bioreactors And Evaluation Of Genetic Relationships And Prevalence Of Vancomycin Resistance Among Environmental Enterococci, Bina S. Nayak Nov 2009

Microbial Population Analysis In Leachate From Simulated Solid Waste Bioreactors And Evaluation Of Genetic Relationships And Prevalence Of Vancomycin Resistance Among Environmental Enterococci, Bina S. Nayak

USF Tampa Graduate Theses and Dissertations

Degradation of the several million tons of solid waste produced in the U.S. annually is microbially mediated, yet little is known about the structure of prokaryotic communities actively involved in the waste degradation process. In the first study, leachates generated during degradation of municipal solid waste (MSW) in the presence (co-disposal) or absence of biosolids were analyzed using laboratory-scale bioreactors over an eight-month period. Archaeal and bacterial community structures were investigated by denaturing gradient gel electrophoresis (DGGE) targeting 16S rRNA genes. Regardless of waste composition, microbial communities in bioreactor leachates exhibited high diversity and temporal trends. Methanogen sequences from a …


Fireproofing The Lawn: Reclaimed Water And Polybrominated Diphenyl Ethers In Tampa Bay, Ryan C. Davis Oct 2009

Fireproofing The Lawn: Reclaimed Water And Polybrominated Diphenyl Ethers In Tampa Bay, Ryan C. Davis

USF Tampa Graduate Theses and Dissertations

Reclaimed water has increased in popularity as a means to recycle water and thus decrease the amount of wasteful water use. This process is widely used in Tampa Bay for watering of lawns. This increase in popularity and use has raised questions as to what contaminants are in the reclaimed water.

The purpose of this study was to analyze reclaimed water for contaminants believed to be detrimental to health and conduct interviews to ascertain perceptions of risk in the local population. As water reuse grows in popularity further research will need to be conducted to address potential human health concerns. …


Mercury Perception, Community Awareness And Sustainability Implications For The Tampa Bay Region, Florida, Trina Halfhide Oct 2009

Mercury Perception, Community Awareness And Sustainability Implications For The Tampa Bay Region, Florida, Trina Halfhide

USF Tampa Graduate Theses and Dissertations

Over one million acres of land and water in Florida has been classified as impaired by mercury. Approximately 80% of national fish advisories are issued due to mercury contamination. There have been a number of consumption advisories in the Tampa Bay Region for locally eaten fish such as largemouth bass (

Micropterus salmoides), bowfin (Amia calva), and alligator gar (Lepisosteus osseus). The main purpose of this study was to determine if there is adequate dissemination of mercury related risk information by government agencies to recreational and subsistence fishermen in the Tampa Bay Region. This research …


Shaping The Dream: A Survey Of Post-World War Ii St. Petersburg, 1946-1963, Jon L. Wilson Oct 2009

Shaping The Dream: A Survey Of Post-World War Ii St. Petersburg, 1946-1963, Jon L. Wilson

USF Tampa Graduate Theses and Dissertations

St. Petersburg stood on the cusp of great change in 1946. Returning veterans sought jobs and housing, and St. Petersburg experienced its first major growth era since the real estate boom of the 1920s. The decade of the 1950s saw the city's population leap from 96,738 to 181,298, an 87 percent increase driven by boosters and national publicity about the city's leisurely ambience. Tract houses replaced remaining pockets of pasture and pine trees as subdivisions sprawled toward the city limits and beyond. On fertile truck-farming acreage called Goose Pond, developers built Central Plaza, a shopping center positioned to drain business …


Additive Latent Variable (Alv) Modeling: Assessing Variation In Intervention Impact In Randomized Field Trials, Peter Ayo Toyinbo Oct 2009

Additive Latent Variable (Alv) Modeling: Assessing Variation In Intervention Impact In Randomized Field Trials, Peter Ayo Toyinbo

USF Tampa Graduate Theses and Dissertations

In order to personalize or tailor treatments to maximize impact among different

subgroups, there is need to model not only the main effects of intervention but also the variation

in intervention impact by baseline individual level risk characteristics. To this end a suitable

statistical model will allow researchers to answer a major research question: who benefits or is

harmed by this intervention program? Commonly in social and psychological research, the

baseline risk may be unobservable and have to be estimated from observed indicators that are

measured with errors; also it may have nonlinear relationship with the outcome. Most of the …


Sugar Ethanol In Florida: Economic, Agricultural, And Environmental Aspects, Joshua F. Berger Oct 2009

Sugar Ethanol In Florida: Economic, Agricultural, And Environmental Aspects, Joshua F. Berger

USF Tampa Graduate Theses and Dissertations

Ethanol production has been widely perceived as a solution to the global energy crisis, with the added benefit of reinvigorating declining agricultural economies. Moves towards dedicating crop production to ethanol however have raised a number of concerns related to its economic and environmental consequences. Missing from this debate is a consideration of the ways in which sugar can be used as a feedstock for ethanol, an issue that is especially pertinent within the state of Florida. The national commitment and scale of corn ethanol production in the U.S. has largely meant a lack of focus on other feedstocks which could …


Cultural Competence In Health Care: A Client-Based Perspective, Karon L. Phillips Oct 2009

Cultural Competence In Health Care: A Client-Based Perspective, Karon L. Phillips

USF Tampa Graduate Theses and Dissertations

In response to the presence of health disparities among a diverse population of older adults, creating culturally competent health care services has emerged as a possible method to help reduce and eventually eliminate inequalities in health care. However, little information exists concerning the effectiveness of cultural competence, and even less is known about how culturally competent clients perceive their providers to be. This dissertation examined a number of indicators related to cultural competence, including the predictors of client-provider racial/ethnic concordance, client perceptions of the interpersonal sensitivity of their health care providers, and the overall satisfaction with care reported by older …


Living With Sugar: Socioeconomic Status And Cultural Beliefs About Type 2 Diabetes Among Afro-Caribbean Women, Chrystal A.S Smith Oct 2009

Living With Sugar: Socioeconomic Status And Cultural Beliefs About Type 2 Diabetes Among Afro-Caribbean Women, Chrystal A.S Smith

USF Tampa Graduate Theses and Dissertations

In the U.S., individuals of Afro-Caribbean and Latino descent are two to three times more likely to develop type 2 diabetes than non-Hispanic whites. Caribbean and Latin America migrants, particularly minority women bear a disproportionate burden of type 2 diabetes and its risk factors. The purpose of this research is to investigate if Afro-Caribbean women share a cultural belief model about type 2 diabetes and how this belief model, along with structural barriers to health care, influence disease risk and management.

A sample of 40 women, primarily Jamaican and Trinidadian, 35 to 90 years of age previously diagnosed with type …


Evaluation Of A Self-Monitoring Program To Increase Treatment Integrity Of Behavior Intervention Plans, Lela E. Taylor Oct 2009

Evaluation Of A Self-Monitoring Program To Increase Treatment Integrity Of Behavior Intervention Plans, Lela E. Taylor

USF Tampa Graduate Theses and Dissertations

The growing number of school-aged children displaying challenging behavior has increased the need for effective interventions. School-based consultants (SBC) report using behavioral consultation to assist teachers in designing behavior intervention plans (BIP) that help students engage in appropriate behavior in the classroom. Research indicates that direct training methods increase teacher's implementation of the BIP. One commonly used direct training method, performance feedback (PF), is used to assess teachers' treatment integrity. Research also indicates that checklists (non-direct measures) are more cost efficient methods. The purpose of this paper was to evaluate a direct training method used to train teachers to self-monitor …


Medicare Part D Program: Prescription Drug Plan Copayment Structure And Premium Sensitivity, Rui Dai Oct 2009

Medicare Part D Program: Prescription Drug Plan Copayment Structure And Premium Sensitivity, Rui Dai

USF Tampa Graduate Theses and Dissertations

Since January 2006 Medicare beneficiaries have the option to purchase prescription drug benefits from Medicare under the Part D program. The addition of outpatient drugs to the Medicare programs reflects Congress’ recognition of the fundamental change in recent years in how medical care is delivered in the U.S. It recognizes the vital role of prescription drugs in the health care delivery system and the need to modernize Medicare to assure their availability to Medicare beneficiaries. The Medicare Prescription Drug Improvement and Modernization Act of 2003 (MMA) created the Medicare drug benefit and specified a standard plan. The law also enables …


Molecular Intervention In Mouse Models Of Amyotrophic Lateral Sclerosis And Alzheimer’S Disease – Neuropathology And Behavior, Steven Prescott Bennett Oct 2009

Molecular Intervention In Mouse Models Of Amyotrophic Lateral Sclerosis And Alzheimer’S Disease – Neuropathology And Behavior, Steven Prescott Bennett

USF Tampa Graduate Theses and Dissertations

Neurodegeneration describes the progressive loss of structure and function of neurons, leading ultimately to cell and organism death. Although the initiating factors of neurodegenerative diseases such as Alzheimer’s, Parkinson’s, Huntington’s, and Amyotrophic Lateral Sclerosis may be different, they share common pathophysiologies. Proteinopathies, as these diseases are now termed, are characterized by atypical deposits of proteins, often due to misfolding. Associated with these deposits are dysfunctional mitochondria, oxidative stress, disrupted axonal transport, inflammation, and apoptotic cell death. If this occurs in motor neurons, as in ALS, ataxia precedes death with little or no change in cognition. On the other hand, if …


Portraits Of Online Teaching And Learning: The Experiences Of An Instructor And Six Graduate Students In A Course Entitled Educating Students With Autism, Sarah R. Semon Oct 2009

Portraits Of Online Teaching And Learning: The Experiences Of An Instructor And Six Graduate Students In A Course Entitled Educating Students With Autism, Sarah R. Semon

USF Tampa Graduate Theses and Dissertations

Throughout the last decade (1999-2009) Florida's Bureau of Exceptional Education Student Services, in partnership with Institutions of Higher Education created the Florida Virtual ESE program to develop and deliver online professional development courses. The state also provided tuition support for teachers to participate in online professional development coursework to earn credentials necessary to be considered Highly Qualified. Online course delivery is thought to be a cost-effective approach to the provision of professional development for in-service teachers. However, there is a need to examine what it takes to create meaningful online learning experiences that facilitate the goals and objectives particular to …


The Effects Of Professional Development Efforts On Educator Beliefs And Perceptions Of Competency Within A School-Based Response To Intervention Model, Joshua Nadeau Oct 2009

The Effects Of Professional Development Efforts On Educator Beliefs And Perceptions Of Competency Within A School-Based Response To Intervention Model, Joshua Nadeau

USF Tampa Graduate Theses and Dissertations

The purpose of this study was to identify and understand relationships between educators' perceived skills, observed practices, and stated beliefs - as well as the impact of evidence-based professional development upon those relationships - during the first year of ongoing school-based implementation for Florida's Statewide Problem- Solving/Response to Intervention (PS/RtI) Project. The PS/RtI model is conceptualized as providing a data-based template to drive student service delivery decisions; as providing a tiered framework of assessment and evaluation to maximize efficiency of allocated school funds; and as defining the determination of eligibility for special education services to be based solely upon a …


Development Of Three Dimensional Fluid-Structure Interaction Models For The Design Of Surface Acoustic Wave Devices: Application To Biosensing And Microfluidic Actuation, Reetu Singh Oct 2009

Development Of Three Dimensional Fluid-Structure Interaction Models For The Design Of Surface Acoustic Wave Devices: Application To Biosensing And Microfluidic Actuation, Reetu Singh

USF Tampa Graduate Theses and Dissertations

Surface acoustic wave (SAW) devices find uses in a plethora of applications including

but not limited to chemical, biological sensing, and microfluidic actuation. The primary aim of

this dissertation is to develop a SAW biosensor, capable of simultaneous detection of target

biomarkers in fluid media at concentrations of picogram/ml to nanogram/ml levels and removal

of non-specific proteins from sensor surface using the process of acoustic streaming, for potential

chemical sensing, medical, and clinical diagnostic applications. The focus is on the development

of three dimensional finite element structural and fluid-structure interaction models to study wave

propagation and acoustic actuation of fluids …


An Exploratory Analysis Of The Ecological Validity Of A Performance-Based Assessment Of Attention, Eun- Yeop Lee Sep 2009

An Exploratory Analysis Of The Ecological Validity Of A Performance-Based Assessment Of Attention, Eun- Yeop Lee

USF Tampa Graduate Theses and Dissertations

Executive functions impact everyday functioning. An individual’s ability to adapt

to and navigate their physical and social environments is largely determined by the ability

to organize oneself, to plan and to coordinate activities. Despite the wide variety of

cognitive tests that assess various aspects of executive function, there has been little work

to validate the use of these measures in predicting real world functioning (Sbordone,

Seyranian, & Ruff, 2000), particularly in children where characterization of executive

function is less specified. Evaluating the ecological validity of neuropsychological tests

has become an increasingly important topic over the past decade (Chaytor & Schmitter- …


Co-Transcriptional Splicing And Functional Role Of Pkcβ In Insulin-Sensitive L6 Skeletal Muscle Cells And 3t3-L1 Adipocytes, Eden Kleiman Sep 2009

Co-Transcriptional Splicing And Functional Role Of Pkcβ In Insulin-Sensitive L6 Skeletal Muscle Cells And 3t3-L1 Adipocytes, Eden Kleiman

USF Tampa Graduate Theses and Dissertations

PKC

βII is alternatively spliced during acute insulin stimulation in L6 skeletal

muscle cells. This PKC

βII isoform is critical in propagating GLUT4 translocation.

PKC

β protein and promoter dysfunction correlate with human insulin resistance. TZD

treatment ameliorates whole-body insulin-resistance. Its primary target is adipocyte

PPAR

γ, which it activates upon binding. This causes both altered circulating serum FFA

concentrations and adipokine secretion profile. How TZDs affect the intracellular

signaling of skeletal muscle cells is unknown. RT-PCR and Western blot analysis

showed that TZDs elevated PKC

βII by a process that involves co-transcriptional splicing.

PGC1

α overexpression most closely resembled …