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Investigation Of Anemarrhena Asphodeloides And Its Constituent Timosaponin-Aiii As Novel, Naturally Derived Adjunctive Therapeutics For The Treatment Of Advanced Pancreatic Cancer, Catherine B. Marelia

USF Tampa Graduate Theses and Dissertations

Pancreatic adenocarcinoma (PDAC) remains one of the most lethal cancer types, with 92% of patients succumbing to the disease within five years. One of the hallmarks of this intractable disease is its nearly universal resistance to chemotherapeutic intervention. The deoxycytidine analog gemcitabine persists as the primary chemotherapy for advanced PDAC patients despite little improvement to its toxicity and tenuous efficacy over the past two decades. Plant-based drug discovery has a longstanding history and has led to some of the most significant drugs of the modern era, including some chemotherapeutic agents like paclitaxel and camptothecin. Our study analyzed the potential inhibitory …

The Role Of Migration-Related Stress In Depression Among Haitian Immigrants In Florida: A Mixed Method Sequential Explanatory Approach, Dany Amanda C. Fanfan

USF Tampa Graduate Theses and Dissertations

Recognizing, appropriately treating depression, and meeting the mental health needs of the growing number of Haitian immigrants in the United States (US), continue to pose a challenge because of differences in culture, beliefs, idiom of distress, expression of depression as well as specific stressors associated with the migration process. Previous studies, while limited, document high levels of depression among Haitian migrants, and postulated that migration-related stress (MRS) may play a significant role. Aspects of the migration process, more specifically stressors endured during settlement in the US may negatively precipitate the development of depression.

This study used a mixed method sequential …

Patient Experiences And Satisfaction With Homeopathic Treatment In Pune, India, Asmita R. Mhaskar

USF Tampa Graduate Theses and Dissertations

Introduction: Global populations are increasingly pursuing Complementary and Alternative Medicines (CAM) as safe, holistic options to attain health and wellness. Homeopathy is one such system of medicine whose demand is growing across the world, with maximum users in India. Yet, patient satisfaction and experiences with Homeopathy have not been addressed comprehensively in India.

Methods: A two-phase, mixed-methods study was designed to assess patient satisfaction and patient experiences with Homeopathic medicines and clinics in Pune, India. Phase I included the design and validation of a survey on Homeopathy specific experiences in English and Marathi for collecting data. Phase II employed a …

The Spectacle Of The Bomb: Rhetorical Analysis Of Risk Of The Nevada Test Site In Technical Communication, Popular Press, And Pop Culture, Tiffany Wilgar

USF Tampa Graduate Theses and Dissertations

This dissertation is a rhetorical analysis of presentations of risk across three different sites of inquiry: technical communication, the popular press, and pop culture. This dissertation focuses on The Nevada Test Site (NTS), a nuclear testing facility near Las Vegas, Nevada, and analyzes presentations of risk in language of the technical report following an NTS accident in December 1970. Project Baneberry, a routine underground nuclear test, became the accident known as "The Baneberry Vent" when it cracked through the earth and vented into the atmosphere, exposing NTS employees and nearby communities to radiation. Presentations of risk in the technical document …

Demonstration Of Monolithic-Silicon Carbide (Sic) Neural Devices, Evans K. Bernardin

USF Tampa Graduate Theses and Dissertations

Brain Machine Interfaces (BMI) provide a communication pathway between the electrical conducting units of the brain (neurons) and external devices. BMI technology may provide improved neurological and physiological functions to patients suffering from disabilities due to damaged nervous systems. Unfortunately, microelectrodes used in Intracortical Neural Interfaces (INI), a subset of the BMI device family, have yet to demonstrate long-term in vivo performance due to material, mechanical and electrical failures. Many state-of-the-art INI devices are constructed using stacks of multiple materials, such as silicon (Si), titanium (Ti), platinum (Pt), parylene C, and polyimide. Not only must each material tolerate the biological …

A Secure Computing Platform For Building Automation Using Microkernel-Based Operating Systems, Xiaolong Wang

USF Tampa Graduate Theses and Dissertations

Building Automation System (BAS) is a complex distributed control system that is widely deployed in commercial, residential, industrial buildings for monitoring and controlling mechanical/electrical equipment. Through increasing industrial and technological advances, the control components of BAS are becoming increasingly interconnected. Along with potential benefits, integration also introduces new attack vectors, which tremendous increases safety and security risks in the control system. Historically, BAS lacks security design and relies on physical isolation and "security through obscurity". These methods are unacceptable with the "smart building" technologies. The industry needs to reevaluate the safety and security of the current building automation system, and …

Structure-Based Design, Synthesis And Applications Of A New Class Of Peptidomimetics: 'Y-Aa Peptides And Their Derivatives, Ma Su

USF Tampa Graduate Theses and Dissertations

Peptidomimetics can mimic hierarchical structures of peptides and proteins. Thus, they are extensively studied for therapeutic applications. To break the limitation of backbones and frameworks and expand the peptidomimetics family, a new class of peptidomimetics - “γ-AApeptides” was developed. Design of γ-AApeptides is based on the chiral peptide nucleic acids (PNAs) backbone.

The World Health Organization estimates that one -third of all deaths in the world are on account of infectious diseases. AMPs are important because of their high activity against broad spectrum microbes, less susceptible to grow resistance and selectivity in binding to bacterial cells over human cells. γ-AApeptides …

The Impact Of Prior-Prior Year On Federal Student Aid Eligibility, Valerie A. Mockus

USF Tampa Graduate Theses and Dissertations

Each year, millions of Americans complete the Free Application for Federal Student Aid (FAFSA) in hopes of securing federal, state, and institutional funding to support their educational goals. The FAFSA recently changed the age of tax data used to determine eligibility for aid, including the Federal Pell Grant—eligibility for which is often used as a proxy for students with the highest need. This study includes a comprehensive review of the extant literature on the subject of prior-prior year. It is also the first look into the actual impact of the recent shift from Prior Year (PY) tax information to Prior-Prior …

Heart Rate Variability Analysis As A Means Of Real-Time Hypercapnia Detection, Joseph Dituri

USF Tampa Graduate Theses and Dissertations

The motivation for this research is the high prevalence experienced by divers of carbon dioxide (CO₂) issues and concerns throughout their lives. Additionally, CO₂ is naturally occurring, the product of oxidative metabolism, and is undetectable to human senses. Current CO₂ sensor or detection technology is limited to high-cost machines such as arterial blood gas monitors and end tidal CO₂ monitors, or more modern technology relying upon bright lights which measure blood flow. The light technology is notoriously unreliable and does not produce a very effective heart beat allowing a user to detect minimal changes. Heart …

Negotiating My Rainbow: A Self-Study Exploring The Relationship Between Beliefs About Identity And Classroom Practice, Amanda Colborne

USF Tampa Graduate Theses and Dissertations

Teachers bring parts of themselves, among them, gender, age, and race into the classroom. In addition to the routine stress of teaching, lesbian, gay, bisexual and transgender (LGBT) people have the added stress of managing the expression of their sexual orientation in the classroom. This study explores the ways in which my own identity as a lesbian influenced my beliefs about teaching, my “pre-active” curricular-instructional decision-making, and my “interactive” curricular-instructional decision-making (Jackson, 1966). A self-study methodology is used to explore these relationships. Data sources include journaling, lesson plan artifacts, student work samples, photographs of my classroom, an observation and critical …

Message Received? The Relationship Between Graphic Warning Labels, Message Framing, And Psychological Responses Among Smokers, John B. Correa

USF Tampa Graduate Theses and Dissertations

Introduction: This study was designed to evaluate the effects of graphic components and message content on daily smokers’ responses to cigarette pack warning labels. It was hypothesized that graphic warning labels (GWLs) would produce increases in state psychological reactance, that loss-framed messages would generate increases in risk perception and psychological reactance, and that GWLs and gain-framed messages would interact to generate increases in motivation to quit smoking when compared to the GWL/loss-framed condition. It was also hypothesized that trait reactance, smoking behavior, and baseline motivation to quit smoking would moderate effects of the warning label exposures.

Method: In a within-subjects …

The Icarus Floating Membrane Photobioreactor For Microalgae Cultivation In Wastewater: Advancing Technology From Lab To Field Prototype, Melanie Pickett

USF Tampa Graduate Theses and Dissertations

The ICARUS membrane photobioreactor, conceptualized and preliminarily tested at the University of South Florida, provides a viable platform for algae cultivation using wastewater as a growth medium. Progression of the technology is tracked using NASA’s Technology Readiness Level scale, and is herein described. Through the work described in this manuscript, the technology has evolved from TRL 3 to TRL 5. Completing the suggested future work will readily move the technology to TRL 6 and beyond.

The first study investigated the co-location of algal cultivation with wastewater treatment. This coupling provides a steady source of water and nutrients for algal growth. …

Validation Of A New Concept For Measuring Respirable Dusts, Xiao Liu

USF Tampa Graduate Theses and Dissertations

Sampling of airborne dust in industry is influenced by the potential health effects associated with human exposure. Health effects depend on mass concentration and particle size which influences the site of pulmonary deposition. Occupational diseases tend to be associated with dust deposition in specific regions of the respiratory tract. The ACGIH size selective TLVs are expressed in three forms: Inhalable Particulate Matter, Thoracic Particulate Matter, and Respirable Particulate Matter. In pneuomoconioses, the amount of dust deposited in the lungs can be estimated by sampling the respirable fraction. Dose-response relationships are derived by relating the health experience of workers to the …

The Politics Of Medicine At The Late Medici Court: The Recipe Collection Of Anna Maria Luisa De’ Medici (1667 – 1743), Ashley Lynn Buchanan

USF Tampa Graduate Theses and Dissertations

This dissertation analyzes the social, cultural, and political significance of recipes at the late Medici court. In doing so, it examines how the late Medici court used medicinal and pharmaceutical patronage to maneuver politically and socially as well as increase the court’s cultural cache throughout Europe. By the beginning of the eighteenth century, it was clear that the Medici line would end and that the Grand Duchy of Tuscany would become a satellite state of a larger European power. Yet while the late Medici court found themselves increasingly sidelined in the cultural and political landscape of Europe, science and medicine …

On The Feasibility Of Profiling, Forecasting And Authenticating Internet Usage Based On Privacy Preserving Netflow Logs, Soheil Sarmadi

USF Tampa Graduate Theses and Dissertations

Understanding Internet user behavior and Internet usage patterns is fundamental in developing future access networks and services that meet technical as well as Internet user needs. User behavior is routinely studied and measured, but with different methods depending on the research discipline of the investigator, and these disciplines rarely cross. We tackle this challenge by developing frameworks that the Internet usage statistics used as the main features in understanding Internet user behaviors, with the purpose of finding a complete picture of the user behavior and working towards a unified analysis methodology. In this dissertation we collected Internet usage statistics via …

Smart Start For Trauma: A Multiple Baseline Design, Sarah E. Dickinson

USF Tampa Graduate Theses and Dissertations

The purpose of this study was to address gaps in the trauma treatment literature related to the expense and inaccessibility of evidence-based interventions for children with disabilities who have experienced trauma. Another aim of this study was to provide additional support for a newly piloted intervention for children with disabilities who have experienced trauma. This intervention is known as Smart Start: Parenting Tools for Children with Developmental Delay, Social-Emotional Concerns, and Trauma. A non-concurrent multiple baseline method was used to determine whether there was a functional relationship between the intervention and children’s challenging behaviors for five caregiver-child dyads. In addition, …

A Collaborative Electronic Behavior Assessment System (Eba): Validation And Evaluation Of Feasibility, Carlos E. Silvestre

USF Tampa Graduate Theses and Dissertations

This study validated and evaluated the feasibility of a web-based electronic behavior assessment system, ‘eBA’, designed to facilitate collaboration between caregivers and service providers (behavior analysts) in conducting indirect functional behavior assessment (FBA). In Phase 1, the content and the web architecture of the eBA were validated and refined through a formative evaluation by five behavior analysts. In Phase 2, the eBA system was pilot tested with 10 service providers and 10 caregivers using a post-test only control group design to examine the efficiency and quality of the system and identify the levels of satisfaction with the system by the …

Evaluating Video Feedback As An Antecedent Or Consequent Event For Improving Performance Of Dance Skills, Kelsey Myers

USF Tampa Graduate Theses and Dissertations

This study used video feedback to compare the effectiveness of antecedent and consequent feedback. Video feedback was used to increase the performance of dance skills of young dancers. A multiple baseline across subjects with an embedded multi-element comparison was used for three female dancers between the ages of 10 and 11 years old. Antecedent video feedback was given immediately before the performance of a target behavior, and consequent video feedback was given immediately after a performance of a different dance skill. The results show that video feedback increased all targeted skills for subjects, however, there were no differentiated results when …

Testing The Validity And Utility Of A Career And Technical Education Programs Of Study Evaluation Instrument, Alisha D. Hyslop

USF Tampa Graduate Theses and Dissertations

The purpose of this study was to build on the research already completed by the Association for Career and Technical Education (ACTE) in the development of ACTE’s quality Program of Study Framework and accompanying evaluation instrument to examine the validity of the instrument’s results and its utility when used independently by local educators in a pilot test. The study used a two-phase mixed-methods design. In the first phase, 39 participating programs were evaluated using the instrument, consisting of 102 items organized into 12 elements. Representatives of participating programs, either teachers or administrators, then provided quantitative and qualitative feedback about the …

Harnessing Social Norms To Increase Men's Interest In Heed Careers, Joanna R. Lawler

USF Tampa Graduate Theses and Dissertations

Men’s underrepresentation in the female-dominated domains of healthcare, early education, and the domestic sphere, or HEED roles, remains a persistent problem despite the fact that such careers often afford more job security and wage growth than blue-collar work. A growing body of evidence suggests that their lack of participation in HEED roles is not merely due to a skills mismatch, but rather an identity mismatch. I hypothesized that using descriptive and injunctive norms to reframe a stereotypically feminine career as more compatible with manhood could effectively reduce this identity mismatch. More specifically, I predicted that using a dynamic descriptive norm …

Managing A Food Health Crisis: Perceptions And Reactions To Different Response Strategies, Yifei Ren

USF Tampa Graduate Theses and Dissertations

Brand crisis could threaten a company with declining public trust and decreased brand reputation (Greyser, 2009). When confronting with a crisis, the organization should respond immediately and properly so that the crisis can be stopped from escalate into a catastrophe (Davies and Walters, 1998). Crisis type can be divided into the victim, the accident or the intentional clusters according to perceived responsibilities the company should shoulder. Based on these factors, the company should select the most appropriate response strategy or a combination of different response strategies to address the crisis situation. In other words, a match between crisis type and …

Exploring Explicit Fanfiction As A Vehicle For Sex Education Among Adolescents And Young Adults, Donna Jeanne Barth

USF Tampa Graduate Theses and Dissertations

Fanfiction consists of works written by amateurs using pre-existing characters and plots, often shared online for free. Although fanfiction began long before the advent of the internet, the worldwide web has created a platform wherein fanfiction is allowed and encouraged to spread almost unconditionally, reaching new populations and rising slowly but surely into the public eye. As the internet has made fanfiction more accessible and public, it has also increased the number of children and young adults involved in the process. And in the unsupervised wilderness of the internet, sexual content is a common feature of fanfiction, with a varying …

Use Of A Towed Camera System Along The West Florida Shelf: A Case Study Of The Florida Middle Grounds Benthic Marine Communities, Katie S. Davis

USF Tampa Graduate Theses and Dissertations

As technologies advance the study of ocean dynamics, new approaches to vexing problems of scale and process are becoming more widely available. Originally conceived as a tool primarily for indexing the abundance of near-bottom fishes, the Camera-based Assessment and Survey System (C-BASS) may also be an effective tool for monitoring benthic invertebrate resources vulnerable to natural and anthropogenic perturbations, and for characterizing the composition of benthic communities to inform spatial management. Using still images derived from the C-BASS video of benthic transects within the Florida Middle Grounds, I documented the abundance of benthic habitat-forming functional groups—sponges, algae, and corals—and noted …

You’Re Not Helping: Unhelpful Workplace Social Support As A Job Stressor, Cheryl E. Gray

USF Tampa Graduate Theses and Dissertations

While support is generally a helpful resource for employees, support can also serve as a job stressor. Unhelpful workplace social support (UWSS) is any action taken by a supervisor and/or colleague that is intended to benefit another worker but is perceived as unhelpful or harmful by the recipient. A series of three studies identified types of UWSS, developed a measure of UWSS, and established a nomological network of variables related to UWSS. In Study 1, critical incidents were collected from 116 employees, and a content analysis revealed 11 distinct categories of UWSS. A measure of UWSS was developed in Study …

Enhanced Co2 Conversion By The Simultaneous Doping Of Co, Fe, And Mn In The B-Site Of A Lanthanum Perovskite, Adela E. Ramos

USF Tampa Graduate Theses and Dissertations

There is a pressing need for carbon dioxide (CO₂) mitigation technologies as increasing emissions continue to threaten our environment. Carbon capture and storage (CCS) alone would not be able to achieve temperature rise below 2 °C. In addition, CCS cost increases considerably for power generation and other industries where CO₂ separation is necessary. Conversion of CO₂ to usable products is the most economical and feasible solution as it could offset CO₂ separation cost. Liquid fuels are an attractive route since it is a commodity used globally and demand increases with population and economic growth. Conversion …

Evaluating Human-Associated Escherichia Coli Marker Genes For Microbial Source Tracking Applications In Florida, Jacob K. Senkbeil

USF Tampa Graduate Theses and Dissertations

Fecal pollution of surface water can lead to human health issues because waterborne transmission of pathogens is a common cause of gastroenteritis. Genetic markers developed for human-associated Escherichia coli (H8, H12, H14, and H24) are promising tools for microbial source tracking (MST) of sewage in environmental waterbodies but are untested in the US. H gene marker performance characteristics (specificity, sensitivity, and prevalence) were assessed, with the goal of developing a quantitative PCR assay for the markers with the best performance. Individual E. coli isolates from reference samples were tested to determine end-point PCR assay performance. Three hundred E. coli strains …

Effects Of Alternative Seating On Children With Disabilities, Jessica Hoofman

USF Tampa Graduate Theses and Dissertations

Children with disabilities in school settings often display problem behavior. These challenging behaviors can be inattention, disruptions in class, difficulties with transitions between tasks, and low task motivation. These types of behaviors can lead to problems for the students with their peers, teachers, and school staff. One way to decrease problem behavior is to implement antecedent manipulations to prevent problem behavior from ever occurring. One type of antecedent manipulation is using alternative seating in the classroom, such as stability balls or stabili-t stools. However, little research has been conducted to evaluate different types of alternative seating, therefore this study used …

Positive Deviance As A Framework For Understanding Motivations And Barriers To Exercise For University Students At Campus Recreation, René Dario Herrera

USF Tampa Graduate Theses and Dissertations

The purpose of this thesis was to use qualitative research methodologies to better understand motivations and barriers to exercise for university students at campus recreation. The secondary purpose was to identify any correlations between physical activity habits and academic success. Ethnographic data obtained from a positive deviance sample and critically analyzed with feminist and postmodern theory could provide additional validation for campus recreation's value in positively contributing to the academic success of university students.

Participant observation, questionnaire, cultural domain analysis, interview, and focus group provided qualitative data.

Results indicate university students who frequent campus recreation to exercise are highly motivated …

Validation Of The Thermal Work Limit (Twl) Against Known Heat Stress Exposures, Danielle L. Kapanowski

USF Tampa Graduate Theses and Dissertations

Workers are exposed to stressful thermal work environments in multiple industries every day. Methods for assessing heat stress often struggle to balance productivity without compromising the health of the workers. The Thermal Work Limit (TWL) is a method that has been adopted in areas outside of the United States as a viable method for heat assessment that combines health with productivity. TWL recommends a maximum metabolic rate for a given set of environmental conditions, clothing ensemble and acclimatization state. The purpose of this paper was to evaluate the validity of the TWL against a set of heat stress data known …

Une Analyse De La Vertu Dans Trois Tragédies Historiques De Pierre Corneille, Mariela Saad-Delgado

USF Tampa Graduate Theses and Dissertations

Theologians, philosophers, moralists, artists, men and women of letters of the seventeenth century were interested in the notion of "virtue" and the place it should occupy in the education of children and in the life of adults. Because of this interest, literary genres of this period, and more specifically plays, provide us with many references of the word "virtue".

This concept is presented as one of the essential characteristics to be found in a hero and a heroine. However, "virtue" is not a constant concept, for its meaning is determined by the socio-political context, the author's philosophy, and the gender …