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USF Tampa Graduate Theses and Dissertations

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System Threats And Gender Differences In Sexism And Gender Stereotypes, Sophie Lois Kuchynka Jan 2015

System Threats And Gender Differences In Sexism And Gender Stereotypes, Sophie Lois Kuchynka

USF Tampa Graduate Theses and Dissertations

In the United States, women’s persistent gains in structural power may cause backlash among those motivated to preserve the status quo. The proposed study examines the conditions that prompt men and women to endorse sexism and promote gender stereotypes. System justification theory proposes that people are motivated to justify the socio-political system that governs them and threats to the stability of their system can increase individual’s motivated defenses. I expect men to show the strongest motivated defenses when the hierarchy is threatened or viewed as unstable, because to protect group-based interests men will reinforce the legitimacy of the system through …


The Role Of Anxiety Sensitivity In The Relationship Between Posttraumatic Stress Symptoms And Negative Outcomes In Trauma-Exposed Adults, Brittany Belle Kugler Jan 2015

The Role Of Anxiety Sensitivity In The Relationship Between Posttraumatic Stress Symptoms And Negative Outcomes In Trauma-Exposed Adults, Brittany Belle Kugler

USF Tampa Graduate Theses and Dissertations

Background: The development of posttraumatic stress symptoms (PTS) following a traumatic event is related to significant functional impairment, diminished quality of life, and physical health issues. Yet it is not entirely clear why some traumatized individuals experience negative outcomes while others do not. The purpose of this study is to determine the role of several influential factors related to PTS severity and negative outcomes, such as diminished quality of life and physical health issues, following traumatic events. Method: One hundred and twenty-two trauma-exposed adults were recruited through the University of South Florida’s SONA system and through flyers on campus. Subjects …


How You Categorize Influences How Helpful You Are: The Effect Of Categorization Mindset On Consumers’ Social Decisions, Hsiao-Ching Kuo Jan 2015

How You Categorize Influences How Helpful You Are: The Effect Of Categorization Mindset On Consumers’ Social Decisions, Hsiao-Ching Kuo

USF Tampa Graduate Theses and Dissertations

This dissertation demonstrates how categorization mindsets (introduced by Ulkumen et al., 2010) moderate the altruistic behavior of consumers in decisions that have consequences to others besides oneself. Categorization mindset refers to a way of thinking about options, and is induced by simple sorting or categorization tasks. Ulkumen et al. (2010) has shown that mindsets can be unidimensional (in terms of being focused on a single, salient dimension) or multidimensional (in that both salient and non-salient dimensions are processed). Across three experiments, this dissertation finds that a multidimensional mindset (compared to a unidimensional mindset) enhances the preference for other-oriented options among …


Schreibersite: Synthesis, Characterization And Corrosion And Possible Implications For Origin Of Life, Nikita Latesha La Cruz Jan 2015

Schreibersite: Synthesis, Characterization And Corrosion And Possible Implications For Origin Of Life, Nikita Latesha La Cruz

USF Tampa Graduate Theses and Dissertations

We present study of the synthesis and reactions of an analog of the meteoritic mineral schreibersite with formula (Fe,Ni)3P, believed to be a prebiotic source of reactive phosphorus that may have prompted the formation of phosphorylated biomolecules near the time of the origin of life (Pasek and Lauretta, 2005). The mineral was synthesized by mixing stoichiometric proportions of elemental iron, nickel and phosphorus and heating in a tube furnace at 820°C for approximately 235 hours under argon or under vacuum, a modification of the method of Skála and Drábek (2002). The mineral was characterized using X-ray diffractometry (XRD), X-ray photoelectron …


Experimental Reporting And Networks Of Political Information: Lorenzo Magalotti's Framing Of Courts And Nature, Bradley L'Herrou Jan 2015

Experimental Reporting And Networks Of Political Information: Lorenzo Magalotti's Framing Of Courts And Nature, Bradley L'Herrou

USF Tampa Graduate Theses and Dissertations

This thesis explores changes in experimental reporting during the scientific revolution of the seventeenth century. In particular, I examine and compare some of the works of Count Lorenzo Magalotti, namely the Saggi di Naturali Esperienza or Essays on Natural Experiments and the Relazione d'Inghilterra. In 1667, as secretary of the Accademia del Cimento – the Tuscan experimental academy founded in 1657 – Magalotti (1637-1712) authored the Saggi, a collection of experimental reports. These reports included extensive written descriptions of experiments along with dozens of engravings depicting the instruments custom-made for the experiments. Magalotti also served as ambassador and agent of …


Historical And Current Population Patterns Of The Staghorn Coral (_Acropora Cervicornis_) In Dry Tortugas National Park, Kaitlyn Lizza Jan 2015

Historical And Current Population Patterns Of The Staghorn Coral (_Acropora Cervicornis_) In Dry Tortugas National Park, Kaitlyn Lizza

USF Tampa Graduate Theses and Dissertations

Acropora cervicornis was once one of the dominant reef building corals of the Caribbean, Florida Keys, and Dry Tortugas (DRTO), but since the 1970’s populations have been decimated throughout their geographic range. Recently, a repopulation was documented through detailed benthic surveys conducted by the U.S. Geological Survey at three locations (Pulaski Shoal, East Key, and Loggerhead Key) within DRTO. Benthic surveys using the U.S Geological Survey’s Along-Track Reef Imaging System (ATRIS) revealed hundreds of previously undocumented colonies.

These discoveries have provided a unique data-set, allowing a comparison between the historical (1883, 1976) and contemporary distributions (2009, 2011) of A. cervicornis. …


'She Shall Not Be Moved': Black Women's Spiritual Practice In Toni Morrison's The Bluest Eye, Beloved, Paradise, And Home, Rondrea Danielle Mathis Jan 2015

'She Shall Not Be Moved': Black Women's Spiritual Practice In Toni Morrison's The Bluest Eye, Beloved, Paradise, And Home, Rondrea Danielle Mathis

USF Tampa Graduate Theses and Dissertations

‘She Shall Not Be Moved’: Black Women’s Spiritual Practice in Toni Morrison’s The Bluest Eye, Beloved, Paradise, and Home argues that from The Bluest Eye, Morrison’s debut novel, to her 2012 novel, Home, Morrison brings her female characters to voice, autonomy, and personal divinity through unconventional spiritual work. The project addresses the history of Black women’s activist and spiritual work, Toni Morrison’s engagement with unconventional spiritual practice, and closes with a personal interrogation of the author’s connection to Black women’s spiritual practice.


Beauty Is Precious, Knowledge Is Power, And Innovation Is Progress: Widely Held Beliefs In Policy Narratives About Oil Spills, Brenda Gale Mason Jan 2015

Beauty Is Precious, Knowledge Is Power, And Innovation Is Progress: Widely Held Beliefs In Policy Narratives About Oil Spills, Brenda Gale Mason

USF Tampa Graduate Theses and Dissertations

Scholars from diverse perspectives have sought to understand the features and mechanisms that influence the design and implementation of public policy. Some (realists) have emphasized the role that material interests have played while others (idealists) have emphasized the influence of subjective ideas on ‘how policy means’ (Yanow 1996). Recently, observers in both camps have demonstrated curiosity in the influence of culture on policymaking and its consequences. Regrettably, this shared concern has not resulted in much collaboration across epistemological divides.

I argue that narrative analysis provides a way to bridge the divides by specifying an interpretive approach that identifies culture as …


Documenting Perceived Effectiveness Of Community-Based Health Promotion Coalitions: A Grounded Theory Approach, Alyssa Brooke Mayer Jan 2015

Documenting Perceived Effectiveness Of Community-Based Health Promotion Coalitions: A Grounded Theory Approach, Alyssa Brooke Mayer

USF Tampa Graduate Theses and Dissertations

Introduction: Community coalitions with public health-related missions are formal, semi-permanent, action-oriented partnerships comprised of community members, representatives of government agencies, policymakers, and academic partners. Despite their potential to promote sustainable change, coalitions have had mixed success in effecting long-term improvements in community health. There is a need to assist them in developing strategies for improving and sustaining their functionality. The purpose of this study was to improve understanding of the elements of coalition success and sustainability that are vital to health-related community-based participatory research.

Methods: Although the literature describes coalition functions for effecting sustainable programs and policies, most research reports …


Effects Of A Brief Relaxation Intervention On Stress-Related Eating, Laura Lynn Mayhew-Purcell Jan 2015

Effects Of A Brief Relaxation Intervention On Stress-Related Eating, Laura Lynn Mayhew-Purcell

USF Tampa Graduate Theses and Dissertations

The experience of stress may contribute to increased food consumption and selection of unhealthy food options. Resource depletion theory suggests stress temporarily depletes resources needed to regulate behavior. Depletions of self-control may result in subsequent failure to regulate eating behaviors, which is particularly salient in restrained eaters. Restraint theory posits people high in dietary restraint require significant effort to control eating. Emotional eating theory further suggests palatable foods may be used to regulate emotional stress reactions. Relaxation exercises to mitigate stress reactions are recommended in eating and weight management programs, but lack quality scientific support. The current study examined the …


Looking At Levels Of Medicalization In The Institutional Narrative Of Substance Use Disorders In The Military, Chase Landes Mccain Jan 2015

Looking At Levels Of Medicalization In The Institutional Narrative Of Substance Use Disorders In The Military, Chase Landes Mccain

USF Tampa Graduate Theses and Dissertations

The purpose of this research is to examine the institutional narrative of substance use disorders (SUDs) in the U.S. military and the extent to which it reflects the medicalization process. Three general research questions guided my analysis of the narrative surrounding SUDs in the military: (1) How does the military characterize the problems and resolutions of SUDs? (2) How and to what extent does this narrative reflect medicalization? (3) What are the limitations inherent in the institutional narrative of SUDs in the military? In order to address these questions, I draw on three conceptual lenses: (1) The work of Loseke …


Assessment Of The Impact Of Attention Deficit Hyperactivity Disorder On Type 1 Diabetes, Kellee Miller Jan 2015

Assessment Of The Impact Of Attention Deficit Hyperactivity Disorder On Type 1 Diabetes, Kellee Miller

USF Tampa Graduate Theses and Dissertations

Individual day-to-day management and effective control of type 1 diabetes (T1D) is ultimately driven by decisions made by the individual. Individuals with attention deficit hyperactivity disorder (ADHD) have a higher tendency to be inattentive, impulsive, and hyperactive. Attention deficits and impulsivity among adolescents and adults with T1D could result in poor diabetes management through infrequent self-monitoring of blood glucose and inadequate insulin dosing – key components of achieving optimal glycemic control.

This study included 7,380 adolescents and young adults, ages 13-25 years, participating in the T1D Exchange clinic registry (median age 17.4 years, duration 7.7 yrs, 50% female, 81% white). …


The Triumvirate Of Intersectionality: A Case Study On The Mobilization Of Domésticas In Brazil, Kristen Lei Nash Jan 2015

The Triumvirate Of Intersectionality: A Case Study On The Mobilization Of Domésticas In Brazil, Kristen Lei Nash

USF Tampa Graduate Theses and Dissertations

In this thesis, I look at the mobilization of the domestic workers in Brazil as a social movement. In Brazil, the domestic workers have managed to organize continuously for over eight decades using both informal and formal mechanisms to connect workers all over the country in unique ways. By viewing these women and the ways in which they have organized in the framework of a social movement, we can begin to identify their repertoires of contention and how those repertoires have contributed to the successes of the movement. In order to guide this investigation, I ask, how has the doméstica …


Obsidian Source Selection In The Early Bronze Age Cyclades, Jessica Anne Morgan Jan 2015

Obsidian Source Selection In The Early Bronze Age Cyclades, Jessica Anne Morgan

USF Tampa Graduate Theses and Dissertations

From excavations of burial complexes of the Early Bronze Age Cyclades (c. 3000-2200 BC) we know that obsidian was just as important and as widely consumed in burial contexts as it was in contemporaneous household contexts; Early Bronze Age Cycladic tomb assemblages are dominated by beautiful obsidian blades produced through a unique knapping technique reserved for burial contexts (Carter 2007; Dickinson 1994). The lack of sourcing studies in the area is an unfortunate pitfall in Aegean archaeology, as understanding patterns of source selection provides us with precious insight into the complex social structures and behaviors that characterized these ancient communities. …


Women’S Use Of And Decision‐Making Regarding Geo‐Social Networking Applications To Arrange Sexual Experiences, Shireen Mary Noble Jan 2015

Women’S Use Of And Decision‐Making Regarding Geo‐Social Networking Applications To Arrange Sexual Experiences, Shireen Mary Noble

USF Tampa Graduate Theses and Dissertations

The purpose of this thesis was to learn more about geo-social networking applications and how they are used by women to meet sexual partners. Currently, there are no known studies that have looked at heterosexually-oriented geo-social networking applications or at the way women have used these apps for heterosexual sexual encounters. This thesis attempts to begin to bridge this gap in the literature.

For the first study, apps were selected based on their appearance in popular media articles about dating applications. Results generally related to online safety concerns, while occasional features were related to sexual safety concerns. Communication options were …


Effects Of Nicotine Withdrawal On Motivation, Reward Sensitivity And Reward-Learning, Jason A. Oliver Jan 2015

Effects Of Nicotine Withdrawal On Motivation, Reward Sensitivity And Reward-Learning, Jason A. Oliver

USF Tampa Graduate Theses and Dissertations

Research on addictive behavior has traditionally emphasized the role that primary reinforcing effects of drugs of abuse plays in the development and maintenance of dependence. However, contemporary behavioral economic theory and animal models of nicotine dependence suggest the need for greater attention to the impact that response to alternative rewards may have on smoking behavior. The present study sought to investigate the impact of nicotine withdrawal on self-report, behavioral and neural indices of motivation, immediate response to rewards and the capacity to learn and modify behavior in response to positive and negative feedback. Heavy smokers (n = 48) completed two …


Undergraduate College Students’ Attitudes About Internet-Based Mental Health Interventions, Kathleen Palmer Jan 2015

Undergraduate College Students’ Attitudes About Internet-Based Mental Health Interventions, Kathleen Palmer

USF Tampa Graduate Theses and Dissertations

Millennial-aged young adults, often referred to as “digital natives,” comprise the typical college-age population, and there has been a growing number college students at risk for mental health problems (Mowbray, Mandiberg, Stein, Kopels, Curlin, Megivern, Strauss, Collins & Lett, 2006; Eisenberg, Gollust, Golberstein & Hefner, 2007). Suicide is the second leading cause of death among college students (Suicide Statistics, 2014); however, their rate of utilizing mental heath counseling is decreasing. Providing the types of mental health services college students are likely to use can mitigate factors thought to impede their use (e.g., stigma, anonymity, confidentiality), as well as help improve …


Nearest Neighbor Foreign Exchange Rate Forecasting With Mahalanobis Distance, Vindya Kumari Pathirana Jan 2015

Nearest Neighbor Foreign Exchange Rate Forecasting With Mahalanobis Distance, Vindya Kumari Pathirana

USF Tampa Graduate Theses and Dissertations

Foreign exchange (FX) rate forecasting has been a challenging area of study in the past. Various linear and nonlinear methods have been used to forecast FX rates. As the currency data are nonlinear and highly correlated, forecasting through nonlinear dynamical systems is becoming more relevant. The nearest neighbor (NN) algorithm is one of the most commonly used nonlinear pattern recognition and forecasting methods that outperforms the available linear forecasting methods for the high frequency foreign exchange data. The basic idea behind the NN is to capture the local behavior of the data by selecting the instances having similar dynamic behavior. …


Feeling At Home With Grief: An Ethnography Of Continuing Bonds And Re-Membering The Deceased, Blake Paxton Jan 2015

Feeling At Home With Grief: An Ethnography Of Continuing Bonds And Re-Membering The Deceased, Blake Paxton

USF Tampa Graduate Theses and Dissertations

Bereavement scholars Silverman, Nickman, and Klass (1996) have argued that rituals to continue a relationship with the deceased do not have to be considered pathological in nature. Since their work, scholars have offered specific strategies for the bereaved to actively construct a bond after death, including telling stories about those who have died, having imagined conversations with the deceased, celebrating their birthdays and anniversaries, and reviewing artifacts that represent or once belonged to them (among other strategies). Hedtke and Winslade (2004) call these “re-membering” processes by which the deceased can regain active membership in their loved ones lives. This dissertation …


Modeling Intrusive Geometries Of A Shallow Crustal Intrusion: New Evidence From Mount Ellsworth, Utah, Nathan Nushart Jan 2015

Modeling Intrusive Geometries Of A Shallow Crustal Intrusion: New Evidence From Mount Ellsworth, Utah, Nathan Nushart

USF Tampa Graduate Theses and Dissertations

Surface displacements resulting from upper-crustal intrusion of melt are a paramount concern for communities and facilities located in or near active volcanic areas (e.g. Campi Flegrei, Yucca Mtn.). Study of active intrusions such as Campi Flegrei, Italy west of Mt. Vesuvius, is limited to remote observations through geophysical/geodetic procedures. While the surface displacement due to melt emplacement at depth can easily be determined, the geometries and depth of intrusions are often based on simplified assumptions (e.g. spheres and prolate or oblate ellipsoids). These models benefit from data constraining both the geometries of the individual intrusions, and the kinematics and mechanics …


Assessment Of Public Health Risks Associated With Petrochemical Emissions Surrounding An Oil Refinery, Erin L. Pulster Jan 2015

Assessment Of Public Health Risks Associated With Petrochemical Emissions Surrounding An Oil Refinery, Erin L. Pulster

USF Tampa Graduate Theses and Dissertations

Refinery operations have been associated with a wide variety of atmospheric emissions consisting of criteria air pollutants, volatile organic components, hazardous air pollutants as well as other pollutants. With approximately 100 oil refineries in the Wider Caribbean region (WCR), hydrocarbons in this region pose significant environmental and human health risks. One of the oldest and largest refineries in the WCR is the Isla Refineriá, which is located on the island of Curaçao, and has been the basis of historical debates and conflict between the public and the local government over the environmental and human health risks. This research aims to …


Help! I Have To Teach Math: The Nature Of A Preservice Teacher's Experiences Enacting Mathematics Instruction In A Final Internship, Lori Rakes Jan 2015

Help! I Have To Teach Math: The Nature Of A Preservice Teacher's Experiences Enacting Mathematics Instruction In A Final Internship, Lori Rakes

USF Tampa Graduate Theses and Dissertations

The purpose of this case study was to better understand the nature of the experiences of a preservice teacher, self-identified as having mathematics anxiety as she planned and implemented instruction during her internship by answering: What is the nature of the experiences of a preservice teacher, self-identified as having mathematics anxiety, as she planned for mathematics instruction during her final internship? What is the nature of the experiences of a preservice teacher, self-identified as having mathematics anxiety, as she implemented mathematics instruction during her final internship? Using an interpretivist approach to a case study inquiry, I used semi-structured interviews, observations, …


Organic-Inorganic Hybrid Materials Based On Oxyanion Linkers For Selective Adsorption Of Polarizable Gases, Mona Hanafy Mohamed Jan 2015

Organic-Inorganic Hybrid Materials Based On Oxyanion Linkers For Selective Adsorption Of Polarizable Gases, Mona Hanafy Mohamed

USF Tampa Graduate Theses and Dissertations

The separation of industrially important gases into pure supplies that can be used for many practical applications is based mainly on energy intensive methods such as the cryogenic distillation which is costly and energy intensive. Therefore other routes have been introduced to industrial separation of gases such as the selective adsorption using porous solid materials. Zeolites and activated carbon are the most widely used recyclable energy-efficient porous solid materials for industrial gas separations, however the low uptake and selectivity hurdles their commercialization in some separation applications. Metal organic frameworks (MOFs) have been extensively studied as solid porous materials in term …


Glaciological Applications Of Terrestrial Radar Interferometry, Denis Voytenko Jan 2015

Glaciological Applications Of Terrestrial Radar Interferometry, Denis Voytenko

USF Tampa Graduate Theses and Dissertations

Terrestrial Radar Interferometry (TRI) is a relatively new ground-based technique that combines the precision and spatial resolution of satellite interferometry with the temporal resolution of GPS. Although TRI has been applied to a variety of fields including bridge and landslide monitoring, it is ideal for studies of the highly-dynamic terminal zones of marine-terminating glaciers, some of which are known to have variable velocities related to calving and/or ocean-forced melting. My TRI instrument is the Gamma Portable Radar Interferometer, which operates at 17.2 GHz (1.74 cm wavelength), has two receiving antennas for DEM (digital elevation model) generation, and images the scenes …


Hpv Vaccine Decision-Making Among Male Sexual Minorities: An Integrative Theoretical Framework For Vaccine Promotion, Christopher W. Wheldon Jan 2015

Hpv Vaccine Decision-Making Among Male Sexual Minorities: An Integrative Theoretical Framework For Vaccine Promotion, Christopher W. Wheldon

USF Tampa Graduate Theses and Dissertations

Men who have sex with men (MSM) are at increased risk of anal cancer as a result of anal HPV infection. Routine HPV vaccination is recommended for all MSM up through age 26; however, vaccine uptake among this population is low. The Integrative Model of Behavioral Prediction (IM) was used to identify, describe, and explain psychosocial factors related to HPV vaccine decision-making for young MSM. A sequential mixed-methods approach consisting of semi-structured interviews, a quantitative survey, and a qualitative open-ended survey was used to address the following aims: (1) Determine salient outcome, normative, efficacy, and control beliefs related to HPV-vaccination …


Achieving Reliable Generation \& Delivery Of Energy Through Robust Optimization, Anna Danandeh Jan 2015

Achieving Reliable Generation \& Delivery Of Energy Through Robust Optimization, Anna Danandeh

USF Tampa Graduate Theses and Dissertations

In this dissertation, we elaborate on the inherent risks and uncertainties in power systems and associated industries, and develop practical solution methods to eliminate their adverse effects.

our research agenda consists of practice-driven problems in different stages of power generation as follows. (1) Affordable fuel procurement through developing a comprehensive fuel supply chain design and operations planning system for electricity generation companies, (2) reliable electricity generation through incorporating dynamic asset rating concept in the unit commitment problem, and (3) efficient demand management through proposing a job scheduling model for effective local generation consumption.

Since reliability cannot be compromised in energy …


Analysis And Energy Reduction Of Humanoid Robot Motions – Stand Up And Sit Down, Ercan Elibol Jan 2015

Analysis And Energy Reduction Of Humanoid Robot Motions – Stand Up And Sit Down, Ercan Elibol

USF Tampa Graduate Theses and Dissertations

This research studies the electrical power reduction and control analysis of various motion tasks of a humanoid robot. These motions include standing up and sitting down. Each motion’s tasks have their stable and unstable phases throughout the complete motion cycle. Unstable phases can be caused by gravity forces and improper handling of the upper body of the humanoid robot leaning too forward or backward. Even though most of the dynamic motions seem to be accomplished very simply by humans; standing up and sitting down could create challenges for humanoid robots. Some of the critical challenges researches face are: dynamic nature …


Evaluating The Social Control Of Banking Crimes: An Examination Of Anti-Money Laundering Deficiencies And Industry Success, Erin M. Mulligan Jan 2015

Evaluating The Social Control Of Banking Crimes: An Examination Of Anti-Money Laundering Deficiencies And Industry Success, Erin M. Mulligan

USF Tampa Graduate Theses and Dissertations

Money laundering is a serious crime with potentially wide ranging consequences that have numerous implications for criminological research. However, criminology rarely explores this crime, nor its potential impact on other more central crimes of interest (e.g. drug trafficking or organized crime). The present study adds to a limited body of literature examining money laundering from a criminological perspective, evaluating aspects of its regulation and social control within the banking industry. Several aspects of regulatory oversight and company dynamics such as fine/settlement size, company size, and the likelihood of non-AML/OFAC violations to predict future AML/OFAC violations were evaluated. These analyses largely …


Analyzing The Effect Of Complaints, Investigation Of Allegations, And Deficiency Citations On The Quality Of Care In United States Nursing Homes (2007 – 2012), Kevin E. Hansen Jan 2015

Analyzing The Effect Of Complaints, Investigation Of Allegations, And Deficiency Citations On The Quality Of Care In United States Nursing Homes (2007 – 2012), Kevin E. Hansen

USF Tampa Graduate Theses and Dissertations

The quality of care in nursing homes has been evaluated from many varying perspectives, but few studies have analyzed quality in light of complaints made to state survey agencies by residents, their family members, or other individuals interacting with the nursing home. This study analyzed complaints, investigation of complaint allegations, and complaint-related deficiency citations to determine their effect, if any, on the quality of care in nationwide nursing homes. Using the Online Survey Certification and Reporting (OSCAR) survey dataset for facility characteristics and the complaint investigation dataset for outcomes of complaint investigation, analyses conducted included descriptives, correlations, conceptual mapping for …


Fabrication Of Tissue Precursors Induced By Shape-Changing Hydrogels, Olukemi O. Akintewe Jan 2015

Fabrication Of Tissue Precursors Induced By Shape-Changing Hydrogels, Olukemi O. Akintewe

USF Tampa Graduate Theses and Dissertations

Scaffold based tissue reconstruction inherently limits regenerative capacity due to inflammatory response and limited cell migration. In contrast, scaffold-free methods promise formation of functional tissues with both reduced adverse host reactions and enhanced integration. Cell-sheet engineering is a well-known bottom-up tissue engineering approach that allows the release of intact cell sheet from a temperature responsive polymer such as poly-N-isopropylacrylamide (pNIPAAm). pNIPAAm is an ideal template for culturing cell sheets because it undergoes a sharp volume-phase transition owing to the hydrophilic and hydrophobic interaction around its lower critical solution temperature (LCST) of 32°C, a temperature close to physiological temperature. Compared to …