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Role Of Hla-Drb1 Fucosylation In Anti-Melanoma Immunity, Daniel K. Lester
Role Of Hla-Drb1 Fucosylation In Anti-Melanoma Immunity, Daniel K. Lester
USF Tampa Graduate Theses and Dissertations
Melanoma is the one of the most lethal skin malignancies due to its ability to rapidly metastasize and evade the immune system. One factor that influences melanoma’s ability to metastasize and evade the immune system is the tumor microenvironment. The tumor microenvironment is a complex ecosystem that consists of melanoma cells interacting with different proteins and cell types such as cytokines, extra cellular matrix proteins, and various immune cells. While different immune cells can have various implications in the tumor microenvironment, some tumor infiltrating lymphocytes (TIL) have the potential to suppress these tumors. Recent therapeutic strategies aim to enhance TILs …
Diet And Salivary Microbiome On Cardiovascular Risk And Glycemic Control In Participants With And Without Type 1 Diabetes: The Cacti Study, Tiantian Pang
USF Tampa Graduate Theses and Dissertations
Introduction: The prevalence of type 1 diabetes mellitus (T1DM) has been increasing drastically in the United States. People with T1DM are at a higher risk of developing diabetes-related complications, including cardiovascular disease (CVD). Diet is one of the most modifiable factors and healthy eating could reduce CVD risk among individuals with T1DM. The current 2015-2020 Dietary Guidelines for Americans focus on overall healthy eating patterns rather than individual foods and nutrients. A healthy dietary pattern or high-quality diet can be measured by diet quality indexes, and generally contains minimal ultra-processed foods (UPF). Although substantial evidence has linked poor diet quality …
The Redesign And Evaluation Of A Higher Education Online Instructor Certification Program, Lindsey W. Mercer
The Redesign And Evaluation Of A Higher Education Online Instructor Certification Program, Lindsey W. Mercer
USF Tampa Graduate Theses and Dissertations
The following exploratory case study is a program evaluation of a certification program for online instructors at a high-enrollment, 4-year research-intensive university in the southeast. Since 2014 the Online Instructor Certification (OIC) has operated as the predominant platform for preparing faculty to teach online at the site of study. The OIC contributes to meeting institutional strategic initiatives including accreditation and goals from the state board of governors. Using the Kirkpatrick training evaluation model, this study evaluated the OIC on the first three levels including how participants perceived the certification (Level 1), what participants learned (Level 2), and how participants applied …
Histone Deacetylase 8 Is A Novel Therapeutic Target For Mantle Cell Lymphoma And Preserves Natural Killer Cell Cytotoxic Function, January M. Watters
Histone Deacetylase 8 Is A Novel Therapeutic Target For Mantle Cell Lymphoma And Preserves Natural Killer Cell Cytotoxic Function, January M. Watters
USF Tampa Graduate Theses and Dissertations
This study demonstrates for the first time that HDAC8 function is critical for MCL survival, and abrogating its activity in human primary NK cells does not interfere with NK IgG antibody directed ADCC therapies ex vivo. Human NK cells, isolated from healthy donors, are highly resistant to HDAC8 inhibitor treatment with PCI-34051. Even at the highest concentration, 20uM, no toxicity was observed. Conversely, MCL cell lines representative of the aggressive MCL subtype, classical MCL, were especially sensitive to PCI-34051, an HDAC8 selective inhibitor, treatment. Blocking HDAC8 activity and/or abrogating expression through shRNA silencing induced significant DNA damage, hyperacetylation of SMC3, …
Understanding And Measuring Family–Teacher Partnerships, Emily L. Baton
Understanding And Measuring Family–Teacher Partnerships, Emily L. Baton
USF Tampa Graduate Theses and Dissertations
It has long been acknowledged that there is an important bond between families and schools that enriches the child’s behavior and academic life. The benefits of parent–school partnerships in a child’s education extend beyond the child, benefitting the families and educational staff as well. Terminology, definitions, and practices within the continuum of parent–school partnerships (Goodall & Montgomery, 2014) currently vary. The three most common term of the continuum are (a) family involvement, (b) family engagement, and (c) parent–school partnerships.Firstly, this dissertation sought to build upon the knowledge around the terminology and definition used to explain families and the education system …
How Feeling Like A Minority Affects Preferences For Autonomous Digital Interfaces, Ye Seul Kim
How Feeling Like A Minority Affects Preferences For Autonomous Digital Interfaces, Ye Seul Kim
USF Tampa Graduate Theses and Dissertations
This dissertation examines the novel aspect of minority perception and how feeling-like-a-minority influences the consumption of digital interfaces in a service context. The focus on the perception of minority consumers is important given greater emphasis on minority-related issues catalyzed by recent social events. Examining the effects on the choice likelihood for digital interfaces such as service robots is also relevant given the increasing widespread use of such technology. The findings across eight studies including six online studies and two field experiments demonstrate that individuals who perceive themselves as a minority in a service setting show defensive behavior by choosing a …
Teaching And Learning Together: Situating Information Literacy In The Library Social Services Landscape Of Practice Through Online Scenario-Game-Based Training, Denise R. Shereff
Teaching And Learning Together: Situating Information Literacy In The Library Social Services Landscape Of Practice Through Online Scenario-Game-Based Training, Denise R. Shereff
USF Tampa Graduate Theses and Dissertations
A scoping literature review and a qualitative case study were conducted in this dissertation research to explore formal information literacy instruction and professional development for librarians and social workers in the context of library social services. This research provides avenues for increasing understanding about how each is prepared to provide mental health and social service information and resources in public libraries.The scoping literature review was conducted on 19 studies published since 2002 focusing on librarians’ roles in information literacy instruction in social worker education. Articles were reviewed according to published Scoping Review guidelines. Trends were described regarding instructional and technological …
Head Movement Behaviors In Various Communication Environments, Angkana Lertpoompunya
Head Movement Behaviors In Various Communication Environments, Angkana Lertpoompunya
USF Tampa Graduate Theses and Dissertations
In a complex environment with only a single-source speech target, modern hearing aids can improve signal-to-noise ratios (SNRs) by using directional microphones, and consequently, improve speech intelligibility. However, in many realistic listening situations where there are multiple sound sources, especially in a turn-taking conversation, improving the SNRs in one location may come at a cost of another equally important location. Critically, the hearing aid user is also unlikely to retain a static head orientation to which the hearing aids reference in these complex environments. For this reason, modern premium hearing aids are now equipped with motion sensors (e.g., accelerometers) to …
Apkcs Role In Neuroblastoma Cell Signaling Cascades And Implications Of Apkcs Inhibitors As Potential Therapeutics, Sloan Breedy
Apkcs Role In Neuroblastoma Cell Signaling Cascades And Implications Of Apkcs Inhibitors As Potential Therapeutics, Sloan Breedy
USF Tampa Graduate Theses and Dissertations
Neuroblastoma (NB) is a cancer that develops in the neuroblasts. It is the most common cancer in children under the age of 1 year, accounting for approximately 6% of all cancers. The prognosis of NB is linked to both age and degree of cell differentiation. This results in a range of survival rates for patients, with outcomes ranging from recurrence and mortality to high survival rates and tumor regression. Our previous work indicated that PKC-ι promotes cell proliferation in NB cells through the PKC-ι/Cdk7/Cdk2 cascade. We report on two atypical protein kinase inhibitors as potential therapeutic candidates against BE(2)-C and …
Eeg Classifier Validation Methods For Neuroprosthetic Hand Development, Keigo Yamauchi
Eeg Classifier Validation Methods For Neuroprosthetic Hand Development, Keigo Yamauchi
USF Tampa Graduate Theses and Dissertations
To date, many challenges have been reported in the development of neuroprosthetic hands using EEG and neural signals. In this study, we report the results of a literature review on Brain Computer Interface (BCI) technology, an investigation of estimation methods using applications in MATLAB, and the results of Electroencephalography (EEG) classification to assist in the development of neural prosthetic hands using biological signals such as EEG. Confusion Matrix was created using Motor Imagery (MI) data as the predictive value, and the average accuracy of more than 90% was obtained for the K-Nearest Neighbor (KNN) and decision tree method. The results …
Young Adult Cancer Patients And Survivors’ Adherence To Healthy Eating And Physical Activity Guidelines, Sandra Soca Lozano
Young Adult Cancer Patients And Survivors’ Adherence To Healthy Eating And Physical Activity Guidelines, Sandra Soca Lozano
USF Tampa Graduate Theses and Dissertations
Many Adolescents and Young Adult (AYA) cancer patients/survivors do not engage in healthy eating and physical activity recommendations. The present study assessed the role of race/ethnicity, health literacy, and home environmental influences and its association with adherence to healthy eating and physical activity. AYA patients/survivors from Moffitt Cancer Center (n = 273) completed an anonymous online survey. Self-reported measures about eating habits, physical activity, health literacy, and social support were used. Black/African Americans reported worse eating habits than White and Hispanic participants. Obese participants showed a similar trend compared to all other Body Mass Index groups. Adherence to physical activity …
Using The Genetic Counseling Skills Checklist To Characterize Prenatal Genetic Counseling, David A. Cline
Using The Genetic Counseling Skills Checklist To Characterize Prenatal Genetic Counseling, David A. Cline
USF Tampa Graduate Theses and Dissertations
Genetic Counseling relies on communication skills to help patients understand and adapt to a genetic disease or risk. However, little is known about which skills are most commonly used or the extent to which genetic counseling sessions vary. A novel process measure titled the "Genetic Counseling Skills Checklist" (GCSC) was developed in a prior pilot study and includes 8 broad categories each consisting of 5-8 skills. This study is the first to apply the final GCSC to characterize 20 mock prenatal sessions conducted by 5 genetic counselors (GCs) for 2 prenatal indications using 3 trained actors as patients. Two experienced …
Comparing Mortality In Response To Simulated Climate Change In The Harvester Ant, Pogonomyrmex Badius, And The Fire Ant, Solenopsis Invicta, Haley Depner
USF Tampa Graduate Theses and Dissertations
With the rapid transport of plants, produce, and goods out of its South American home, the fire ant, Solenopsis invicta, has invaded continents on a global scale. In the United States alone, S. invicta is responsible for an estimated $1 billion in damages annually. In contrast to the invasive fire ant, Florida’s native harvester ant, Pogonomyrmex badius, is a keystone seed disperser, providing seed relocation benefits to Florida’s sandhill wildfire-adapted habitats. Seed relocation reduces seedling competition for nutrients with the parent plant, reduces predation of seeds by rodents, increases nutrient loads associated with ant mound soils, and protects seeds from …
Advocating For Diversity, Equity, And Inclusion: A Study Of The Nhl’S #Hockeyisforeveryone Campaign On Twitter, Jessica Martinez
Advocating For Diversity, Equity, And Inclusion: A Study Of The Nhl’S #Hockeyisforeveryone Campaign On Twitter, Jessica Martinez
USF Tampa Graduate Theses and Dissertations
With more than 6.8 million followers on Twitter (as of Feb. 2023), the National Hockey League (NHL) has a large platform that has the potential to influence societal change not only in the United States and Canada, but also globally. This study aims to understand how corporate social responsibility initiatives pair with diversity, equity, and inclusion (DEI) programs. Furthermore, this research seeks to understand how organizations communicate these messages with their publics through social media. This study specifically examines news frames and charity support behaviors implemented by the NHL in messages about its DEI campaign, “Hockey Is For Everyone,” and …
Identifying Barriers And Facilitators To Family Communication Regarding Genetic Testing For Hereditary Cancer, Andrea K. Shields
Identifying Barriers And Facilitators To Family Communication Regarding Genetic Testing For Hereditary Cancer, Andrea K. Shields
USF Tampa Graduate Theses and Dissertations
Cascade testing, whereby at-risk family members are tested for known pathogenic or likely pathogenic (P/LP) variants in high risk cancer genes, provides the opportunity for changes in medical management (e.g., increased surveillance to detect cancer early or preventative surgery to reduce cancer risk). However, the rates of cascade testing are low which suggests that one-time communication may be insufficient to prompt action among family, and an increase in understanding of how to promote ongoing communication about genetic testing within families is needed. We surveyed individuals with P/LP variants in inherited cancer genes and conducted multiple linear regression with forward analysis …
Bookends: Freemasonry In Russia, Past And Present, James Patrick Greene
Bookends: Freemasonry In Russia, Past And Present, James Patrick Greene
USF Tampa Graduate Theses and Dissertations
This thesis seeks to explore Russian Freemasonry in both the reign of Peter I and in theRussian Federation following the collapse of the Soviet Union, two periods where the relevant scholarship has largely fallen silent. The first chapter argues that early Masonic influences were both present at the court of Peter I and accepted by the Tsar. These intellectual trends, traceable in the libraries, social connections, and writings of individual Jacobites, would reemerge in the institutional Freemasonry in the reign of Catherine II. The printing and translation activities of Novikov and Lopukhin indicate a strong interest in these mystical ideas …
Healthcare Decision Makers' Perspectives On Barriers And Facilitators To Hiring Genetic Counselors In Huntington Disease (Hd) Clinic Settings, Bailey Hummel
USF Tampa Graduate Theses and Dissertations
Huntington disease (HD) is a hereditary, neurodegenerative autosomal dominant disorder for which there are currently no effective options to prevent the onset of symptoms. Although meeting with a genetic counselor (GC) is recommended as part of national guidelines for predictive HD genetic testing and a GC is required for Centers of Excellence, not all HD centers have hired a GC. To explore drivers for, valued outcomes of, and barriers to the creation of GC positions in clinics that treat patients with HD, we conducted semi-structured interviews with 11 individuals involved with HD clinics and/or hiring decisions at 8 clinics across …
Consumer Purchase Intent In Opinion Leader Live Streaming, Jihong Huo
Consumer Purchase Intent In Opinion Leader Live Streaming, Jihong Huo
USF Tampa Graduate Theses and Dissertations
The COVID-19 prompted the live-streaming industry to become popular, and live streaming by opinion leaders became a new way of shopping. In live-streaming by opinion leaders, the time from understanding the product to completing the purchase behavior is short; opinion leaders, in turn, use live-streaming to boost sales and personal exposure. Despite the popularity of opinion leaders' live consumption, there are still relatively few studies on it. Therefore, this paper will study what factors promote consumers' purchase intention during the live streaming of opinion leaders.Using the Stimulus-Organism-Response Model (SOR) as a theoretical framework, this paper uses a quantitative research approach …
Piloting A Spanish-Language Web-Based Tool For Hereditary Cancer Genetic Testing, Gretter Manso
Piloting A Spanish-Language Web-Based Tool For Hereditary Cancer Genetic Testing, Gretter Manso
USF Tampa Graduate Theses and Dissertations
Cancer genetic services (including genetic counseling and testing) help identify patients and families at increased risk of developing cancer so that steps can be taken to reduce risks or find cancers early. Receipt of genetic services in the Hispanic/Latinx population is low due, in part, to a shortage of Spanish-speaking genetic counselors. To address this concern, a 12-minute online tool designed to inform individuals about cancer genetic services was translated into Spanish. The objectives of this pilot study were to determine if the educational tool improves knowledge and informed decision making and to assess usability and appropriateness of the tool …
"Emerging And Submerging": Silence, Commemoration, And Sexual Violence In Minneapolis, Alissa Roy
"Emerging And Submerging": Silence, Commemoration, And Sexual Violence In Minneapolis, Alissa Roy
USF Tampa Graduate Theses and Dissertations
Dedicated in Minneapolis in October 2020, the Survivors Memorial became the first permanent memorial to survivors of sexual violence in the United States. However, as my research reveals, sexual violence has long been a part of the commemorative landscape in northeast Minneapolis. Whereas the Survivors Memorial explicitly commemorates survivors of sexual violence, a much older site, the 1936 Pioneers Monument - commemorates sexual violence through silence. This thesis argues that with the building and dedication of the Survivors Memorial, a different memory than the one embodied within the Pioneers Monument begins to take shape. An older narrative of peaceful conquest …
Framing, Emotion, And Contradiction In The Tampa Bay Times’ Climate Change Coverage, Madison Veeneman
Framing, Emotion, And Contradiction In The Tampa Bay Times’ Climate Change Coverage, Madison Veeneman
USF Tampa Graduate Theses and Dissertations
How the media covers climate change is a crucial issue because it can impact public opinion and influence policy, and local newspapers are an understudied yet essential source of media. Previous media research has utilized framing approaches, considered ideology and hegemony, and begun to seriously examine emotion. The purpose of this research project is to synthesize these approaches to examine how the Tampa Bay Times covers climate change. Using research questions that focus on how the coverage is framed and how emotion is used, I collected two samples of articles from different newspaper sections and conducted textual analysis. I identify …
"Queen Of The Mother-Tucking (Western) World": Authenticity And Nationality On Drag Race, Zane A. Willard
"Queen Of The Mother-Tucking (Western) World": Authenticity And Nationality On Drag Race, Zane A. Willard
USF Tampa Graduate Theses and Dissertations
Against the backdrop of legislation across the United States regulating drag performances, I turn to the reality television (RTV) franchise Drag Race as a popular media site where queer identities are represented. More specifically, I analyze the series RuPaul’s Drag Race: UK vs The World (UKVTW) which is the first series in the franchise to feature participants from different countries competing for the title “Queen of the Mother-Tucking World.” Furthermore, the series suggests it represents “global” drag. Understanding that no singular RTV series can represent a singular global drag identity, I ask: how does the series represent global drag? Turning …
Evaluation Of A Story-Telling Approach To Educate Minority Populations About Inherited Cancer, Celestyn B. Angot
Evaluation Of A Story-Telling Approach To Educate Minority Populations About Inherited Cancer, Celestyn B. Angot
USF Tampa Graduate Theses and Dissertations
Utilization of hereditary cancer genetic counseling and testing services is substantially lower among minority populations compared to white populations due, in part, to lower levels of awareness and knowledge. To help improve awareness, we designed a 7-minute video that uses storytelling to translate knowledge of genetic testing and hereditary cancer to individuals who have a personal history or family history of cancer. Consented participants were asked baseline questions about hereditary cancer and genetic testing, reviewed the video, and provided feedback on its content, understandability, and visual appeal during semi-structured interviews. Data were coded and analyzed to identify themes and determine …
How The Taiwanese Podcast Bailingguo News Framed The 2019 Hong Kong Movement: A Framing Analysis Of The Anti-Extradition Law Amendment Bill, Yu-Fei Chiu
USF Tampa Graduate Theses and Dissertations
Nowadays, people can access different types of media to get information. Podcast is one of them and became more popular in recent years. In Hong Kong, the anti-Extradition Law Amendment Bill movement took place in 2019. In this research, we are looking for the frames that Kylie and Ken as the hosts of the Taiwanese podcast - Bailingguo News used when they talked about the movement. The researcher applied framing theory to conduct this study, using textual analysis to analyze five episodes that mentioned the movement on Hong Kong from Bailingguo News. The researcher extracts the themes in the podcasters' …
The Role Of Eco-Tourism In The Environmental Protection Of The Mountains Of Pamirs, Furough Shakarmamadova
The Role Of Eco-Tourism In The Environmental Protection Of The Mountains Of Pamirs, Furough Shakarmamadova
USF Tampa Graduate Theses and Dissertations
ABSTRACTThe Central Asian nation of Tajikistan became independent in 1991. Tajikistan is a mountainous country with a great potential for tourism development. Nevertheless, there are limitations to the development of eco-tourism. I conducted my study to investigate the potential for developing eco-tourism in the eastern part of Tajikistan (the Pamirs). My overarching question was how does eco-tourism relate to the protection of the environment in Pamirs and can it improve the quality of people's lives? To answer this question, I focused on identifying the Best Management Practices (BMP) of eco-tourism in the region and what specific policies, if any, exist …
The Effects Of An Interactive E-Book On Promoting Idiomatic Competence And Motivation Among L2 Learners Of Arabic Language In Saudi Arabia, Alfaifi Adel
USF Tampa Graduate Theses and Dissertations
Native Arabic speakers used idiomatic expressions such as idioms, formulas, and collocations, in their daily communications. In learning Arabic as a second language (L2), effective communication requires “the ability to understand and use idioms appropriately and accurately in a variety of sociocultural contexts, in a manner like that of native speakers, and with the least amount of mental effort” (Liontas, 2015, p. 441). Yet, promoting L2 idiomatic competence in the classroom and beyond remains a difficult task (Liontas, 2006; Tabatabaei, 2012). The utilization of e-books in the learning environment in L2 teaching in the English language has received much research …
Deconstructing And Decolonizing Identities Of “Gender” And “Sex” When Viewed As Anti-Black: Black Narratives Outside Of The Binary, Didier Salgado
Deconstructing And Decolonizing Identities Of “Gender” And “Sex” When Viewed As Anti-Black: Black Narratives Outside Of The Binary, Didier Salgado
USF Tampa Graduate Theses and Dissertations
How is “Reality” experienced in the Black body? Is “Reality” an objective article which is outside of the realm of personal experience? Assigned sex is often assumed an objective biological phenomenon that exists everywhere and in all communities. Gender is often thought about as a socially constructed form of identity which is expressed in various ways. In this thesis, I critically examine the terror of “reality” on the Black body, looking at the ways that Black people who’ve experienced discomfort with gender and sex categories experience the “world” around them. Diving deeply into their own experiences and the meanings they …
The 'Charm And Distinction' Of Proverbs: The Duality Of The Gem Analogy In Erasmus's Adagia, Blythe Broecker Creelan
The 'Charm And Distinction' Of Proverbs: The Duality Of The Gem Analogy In Erasmus's Adagia, Blythe Broecker Creelan
USF Tampa Graduate Theses and Dissertations
Throughout the Adagia, Erasmus of Rotterdam frequently compares proverbs to precious gems and gemstone jewelry. My interdisciplinary study contributes to the broader discussion of Erasmus’s use of imagery by evaluating the specific qualities Erasmus associates with gemstones as analogous to the qualities he argues synonymously describe proverbs, specifically how both possess and imbue “charm and distinction.” The historical use of gemstones as essential for the display of social status and political power coupled with the contemporaneous belief in amuletic and astral magical properties of gemstones reveals the complex connections Erasmus forges between the qualities of gemstones and proverbs. Erasmus’s marked …
Social Media And Women Empowerment In Nigeria: A Study Of The #Breakthebias Campaign On Facebook, Deborah Osaro Omontese
Social Media And Women Empowerment In Nigeria: A Study Of The #Breakthebias Campaign On Facebook, Deborah Osaro Omontese
USF Tampa Graduate Theses and Dissertations
This paper examines how the March 2022 #BreakTheBias campaign on Facebook was used as an empowerment platform in Nigeria, where women experience gender disparity. Research on the role of social media in women’s empowerment in Nigeria is an area that has not been fully studied. Previous studies have looked at women’s empowerment mainly through an educational or political lens, neglecting how social media have also been effective in empowering women. Other researchers have studied how women utilize social media platforms for leisure, entertainment, and media sharing. In the present study, non-probability sampling was used to identify 20 posts that convey …
Process Automation And Robotics Engineering For Industrial Processing Systems, Drake Stimpson
Process Automation And Robotics Engineering For Industrial Processing Systems, Drake Stimpson
USF Tampa Graduate Theses and Dissertations
Automation in industrial systems applications has emerged as the fundamental solution for improving quality, production rate, and efficiency of a process. Much of the recent popularity surrounding the transition of processes from manually operated tasks to automated systems can be attributed to the concept of Industry 4.0, which outlines the fundamental guidelines for integrating cyber-physical systems into industrial processes. Due to rapid advancement of technology in robotics and automation as well as the increase in accessibility of resources to this technology, the capability to develop automated systems has become feasible for small-scale enterprise. This work presents a two-part initiative to …