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Synthesis Of Novel Sn38-Aspirin Prodrugs For The Treatment Of Hepatocellular Carcinoma, Zhimin Chen, Yi Luo, Aiping Fang, Chen Fan, Chenjuan Zeng
Synthesis Of Novel Sn38-Aspirin Prodrugs For The Treatment Of Hepatocellular Carcinoma, Zhimin Chen, Yi Luo, Aiping Fang, Chen Fan, Chenjuan Zeng
Turkish Journal of Chemistry
Hepatocellular carcinoma (HCC) is the most common primary liver malignancy and is a leading cause of cancer-related death worldwide. However, there is no effective chemotherapeutic treatment for HCC and its prognosis remains poor. Consequently, it is urgent to find an efficient antitumor agent to treat HCC. In this study, 7-ethyl-10-hydroxycamptothecin (SN38), the bioactive metabolite of the anticancer drug irinotecan (CPT-11), which is 100-1000 times more potent than CPT-11, was coupled with aspirin to give 4 prodrugs. Their structures were characterized by $^{1}$H~NMR and elemental analysis. The in vitro anticancer activities of these compounds on two human hepatocellular carcinoma cell lines …
Ion-Pair Based Liquid-Liquid Extraction Of Gold(Iii) From Malonate Media Using 2-Octylaminopyridine As An Extractant: Analysis Of Alloys, Minerals, And Drug Samples, Vishal Suryavanshi, Arjun Kokare, Sunil Zanje, Abhijeet Mulik, Rupali Pawar, Makrand Patil, Ashwini Gaikwad, Mansing Anuse, Ganpatrao Mulik
Ion-Pair Based Liquid-Liquid Extraction Of Gold(Iii) From Malonate Media Using 2-Octylaminopyridine As An Extractant: Analysis Of Alloys, Minerals, And Drug Samples, Vishal Suryavanshi, Arjun Kokare, Sunil Zanje, Abhijeet Mulik, Rupali Pawar, Makrand Patil, Ashwini Gaikwad, Mansing Anuse, Ganpatrao Mulik
Turkish Journal of Chemistry
Liquid-liquid extraction of Au(III) from aqueous sodium malonate medium using 2-octylaminopyridine (2-OAP) as an extractant in xylene was achieved. The current work explored the influence of several experimental parameters such as pH, weak acid concentration, extractant concentration, equilibrium time, stripping agents, and aqueous:organic volume ratio on the extraction of Au(III). The experimental results showed that the Au(III) was quantitatively extracted to about 99.5% by 0.05 M 2-OAP in 0.05 M malonate at 5.0 pH. Ammonia solution was used to strip the gold-loaded organic phase and about 99.5% of Au(III) was reversibly extracted into the aqueous phase. Gold(III) was extracted into …
New $N$-4 Piperazinyl Derivatives Of Norfloxacin: Design, Synthesis, And Correlation Of Calculated Physicochemical Parameters With Antibacterial Activity, Gamal El-Din Abou Rahma, Samar Abbas, Mai Shoman, Ibtihal Samir, Rehab Abd El-Baky
New $N$-4 Piperazinyl Derivatives Of Norfloxacin: Design, Synthesis, And Correlation Of Calculated Physicochemical Parameters With Antibacterial Activity, Gamal El-Din Abou Rahma, Samar Abbas, Mai Shoman, Ibtihal Samir, Rehab Abd El-Baky
Turkish Journal of Chemistry
A group of $N-$4 piperazinyl derivatives of norfloxacin was synthesized and identified by different spectroscopic techniques. The $N-$4 piperazinyl substituent in target compounds 2a-2k, 3a-3c, and 4a and 4b was designed to have different electronic, steric, and physicochemical properties. The antibacterial activity of the newly synthesized compounds was evaluated against Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae, and Staphylococcus aureus strains using norfloxacin as a reference. Results showed that most of the tested compounds had higher activity against E. coli and K. pneumoniae than norfloxacin, whereas only five derivatives were more active against P. aeruginosa. On the other hand, all derivatives …
Synthesis, Characterization, And Evaluation Of Antioxidant Activity Of New $\Gamma $- And $\Delta $-Imino Esters, Hasni̇ye Yaşa
Synthesis, Characterization, And Evaluation Of Antioxidant Activity Of New $\Gamma $- And $\Delta $-Imino Esters, Hasni̇ye Yaşa
Turkish Journal of Chemistry
New Schiff bases were synthesized by condensation of methyl-5-(furan-2-yl)-5-oxopentanoate, methyl-4-(furan-2-yl)-4-oxobutanoate, methyl-5-(thiophene-2-yl)-5-oxopentanoate, and methyl-4-(thiophene-2-yl)-4-oxobutanoate with $p$-anisidine and $n$-butylamine. The structures of these synthesized compounds were clarified on the basis of elemental analysis, IR, $^{1}$H NMR, $^{13}$C NMR, and GC-MS spectroscopic techniques. In addition, antioxidant activity of the synthesized compounds was evaluated on the basis of DPPH radical.
Synthesis, Characterization, And Evaluation Of Toxicity Of Quaternary Ammonium Chlorides Of Glucose-Based Este, Anna Parus, Grzegorz Framski
Synthesis, Characterization, And Evaluation Of Toxicity Of Quaternary Ammonium Chlorides Of Glucose-Based Este, Anna Parus, Grzegorz Framski
Turkish Journal of Chemistry
This study presents the synthesis of glucose-based surfactants including quaternary ammonium salts. Their surface properties and influence on the soil environment were investigated. The synthesized quaternary ammonium chlorides of glucose-based ester exhibited good surface tension reduction properties and formed stable foam in contact with water. The results showed that quaternary ester ammonium salts affect the activation of metals (nickel and cadmium) from the soil matrix after their introduction into the soil environment. This phenomenon can increase the bioavailability of these metals. The introduction of glucose surfactants to the soil increased microorganism activity, which may indicate that these compounds were used …
Syntheses And Characterizations Of Cyclotriphosphazenes Containing A 4-Oxy-1-Naphthaldehyde Group, Hani̇fe İbi̇şoğlu, Esra Tanriverdi̇ Eçi̇k, Gönül Yeni̇lmez Çi̇ftçi̇
Syntheses And Characterizations Of Cyclotriphosphazenes Containing A 4-Oxy-1-Naphthaldehyde Group, Hani̇fe İbi̇şoğlu, Esra Tanriverdi̇ Eçi̇k, Gönül Yeni̇lmez Çi̇ftçi̇
Turkish Journal of Chemistry
The nucleophilic substitution reaction of hexachlorocyclotriphosphazene (N$_{3}$P$_{3}$Cl$_{6}$, trimer) (1) with 4-hydroxy-1-naphthaldehyde (2) has been investigated for the first time. 4$^{{\prime}} $-Oxy-1$^{{\prime}} $-naphthaldehyde substituted mono- (3), bis- (4), and tris- (5) cyclotriphosphazenes were obtained from the nucleophilic substitution of compound 1 with 2 in a 1:2 molar ratio in the presence of Cs$_{2}$CO$_{3}$ in acetone at reflux. The pentakis-(6) and hexakis-substituted (7) cyclotriphosphazenes were prepared from the reaction of 1 with 2 in a 1:7 molar ratio using K$_{2}$CO$_{3}$ as a proton abstractor in tetrahydrofuran at room temperature. The structures of the new compounds (3-7) were determined by elemental analysis, FT-IR, …
Synthesis, Molecular Docking, And Pharmacological Evaluation Of Halobenzodithiophene Derivatives Against Alpha-Glucosidase, Urease, And Free Radical Production, Ghulam Abbas, Zahid Hassan, Ahmed Al-Harrasi, Syed Aun Muhammad, Ahood Juma Al-Quraini1, Zahra Khamis Al-Maani1, Ahmed Mohammed Al-Adawai
Synthesis, Molecular Docking, And Pharmacological Evaluation Of Halobenzodithiophene Derivatives Against Alpha-Glucosidase, Urease, And Free Radical Production, Ghulam Abbas, Zahid Hassan, Ahmed Al-Harrasi, Syed Aun Muhammad, Ahood Juma Al-Quraini1, Zahra Khamis Al-Maani1, Ahmed Mohammed Al-Adawai
Turkish Journal of Chemistry
Benzodithiophenes are heterocyclic compounds that have various medicinal and industrial applications. In the present study, halobenzodithiophene, the simplest benzofused thiophene, and its derivatives were synthesized and evaluated against alpha-glucosidase, urease, and free radical production. In the alpha-glucosidase inhibition assay, compound 2,2-bisbenzothiophne (1) exhibited potent activity with IC$_{50}$ = 135 $\pm $ 0.51 $\mu $M, while its derivative 2,7-bis(butoxycarbonyl)-3,6-dichlorobenzo[1,2-$b$;6,5-$b$']dithiophene (2) exhibited promising inhibition with IC$_{50}$ = 263 $\pm $ 0.32 $\mu $M. In the 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical-scavenging assay, compound 2 exhibited promising activity with IC$_{50}$ = 33 $\pm $ 0.42 $\mu $M, while compound 1 showed moderate inhibition in the urease …
Organic Modification Of Montmorillonite And Effect Of Catalytic Selectivity On Thedimerization Of Unsaturated Fatty Acid, Xue Huang, Guoqiang Yin, Guangzhu Feng
Organic Modification Of Montmorillonite And Effect Of Catalytic Selectivity On Thedimerization Of Unsaturated Fatty Acid, Xue Huang, Guoqiang Yin, Guangzhu Feng
Turkish Journal of Chemistry
This study describes the selective synthesis of C36-dimer fatty acids, by reacting unsaturated fatty acid at 533 K for 6 h in the presence of montmorillonite and lithium chloride as the catalyst and cocatalyst, respectively. The catalytic performance of different montmorillonite and organic modified montmorillonite catalysts was investigated in the dimerization of technical grade unsaturated fatty acid, and the influence of the catalyst structure and composition on the catalytic performance was analyzed. All the samples were characterized by X-ray diffraction (XRD), Fourier transform-infrared spectroscopy (FT-IR), scanning electron microscope (SEM), transmission electron microscopy (TEM), thermogravimetry (TG), and dispersion experiments. The results …
Adsorption Of Anionic And Cationic Dyes On Biochars, Produced By Hydrothermalcarbonization Of Waste Biomass: Effect Of Surface Functionalization And Ionicstrength, Ezgi̇ Çağlar, Yusuf Osman Donar, Ali̇ Sinağ, İbrahi̇m Bi̇roğul, Selva Bi̇lge, Kivanç Aydincak, Oleksii Pliekhov
Adsorption Of Anionic And Cationic Dyes On Biochars, Produced By Hydrothermalcarbonization Of Waste Biomass: Effect Of Surface Functionalization And Ionicstrength, Ezgi̇ Çağlar, Yusuf Osman Donar, Ali̇ Sinağ, İbrahi̇m Bi̇roğul, Selva Bi̇lge, Kivanç Aydincak, Oleksii Pliekhov
Turkish Journal of Chemistry
In this work, surface-functionalization agents and various salts as auxiliaries were used to improve the adsorption capacity of biochars produced via hydrothermal carbonization of glucose, cellulose, and hazelnut shell. The effect of surface functionalization with different acids and bases as well as neutral salts on the adsorption of methylene blue and methyl orange was investigated using Boehm titration, Fourier transform infrared spectroscopy, and X-ray photoelectron spectroscopy techniques. Surface functionalization of biochars leads to an increase in the number of oxygen-containing functional groups on the surface, thus increasing the adsorption capacity. To probe the influence of ionic strength on the adsorption …
Synthesis And Antioxidant, Aggregation, And Electronic Properties Of6-Tert-Butyl-1,4-Benzodioxine Substituted Phthalocyanines, Mehmet Sali̇h Ağirtaş, Beyza Cabi̇r, Selçuk Gümüş, Sadi̇n Özdemi̇r, Abdurrahman Dündar
Synthesis And Antioxidant, Aggregation, And Electronic Properties Of6-Tert-Butyl-1,4-Benzodioxine Substituted Phthalocyanines, Mehmet Sali̇h Ağirtaş, Beyza Cabi̇r, Selçuk Gümüş, Sadi̇n Özdemi̇r, Abdurrahman Dündar
Turkish Journal of Chemistry
As a starting material, 7-tert-butyldibenzo [b,e] [1,4] dioxine-2,3-dicarbonitrile was prepared by the reac- tion of 4-tert-butylcatechol with 4,5-dichlorophthalonitrile. Metallophthalocyanine complexes 4-7 were obtained by cyclotetramerization of 7-tert-butyldibenzo [b,e] [1,4] dioxine-2,3-dicarbonitrile. All compounds were characterized by elemental analysis and other spectroscopic methods (IR, UV/Vis, and $^{1}$H NMR). Phthalocyanine compounds remained nonaggregated in tetrahydrofuran at the studied concentration ranges. Metallophthalocyanines 4-7 were tested for their antioxidant activities. The antioxidant activity processes included evaluation of radical-scavenging activity, chelat- ing activity, and reducing power. These compounds were compared to standard antioxidant ascorbic acid. The electronic data of the new compounds were obtained by computational …
Gas Permeability Of Polydimethylsiloxane Membranes Lled With Clinoptilolite Indifferent Cationic Forms, Çi̇ğdem Atalay-Oral
Gas Permeability Of Polydimethylsiloxane Membranes Lled With Clinoptilolite Indifferent Cationic Forms, Çi̇ğdem Atalay-Oral
Turkish Journal of Chemistry
Zeolite-polymer mixed matrix membranes were prepared by lling polydimethylsiloxane (PDMS) with clinop- tilolite in various cationic forms of K, Mg, H, and Na. The membranes were characterized by scanning electron microscopy as well as measurements of O$_{2}, $N$_{2}$ and CO$_{2}$ gas permeabilities. The results indicated the presence of an optimum zeolite loading in the mixed matrix membranes maximizing permeability. The type of the cationic form of clinoptilolite used affected the permeabilities and ideal selectivities of the zeolite-polymer mixed matrix membranes investigated to some degree and some improvements were obtained when compared to the ideal selectivities of the original polymeric membranes.
Nanocapsulation Of Herbicide Haloxyfop-R-Methyl In Poly(Methyl Methacrylate):Phytotoxicological Effects Of Pure Herbicide And Its Nanocapsulated Form Onduckweed As A Model Macrophyte, Samaneh Torbati, Mehdi Mahmoudian, Neda Alimirzaei
Nanocapsulation Of Herbicide Haloxyfop-R-Methyl In Poly(Methyl Methacrylate):Phytotoxicological Effects Of Pure Herbicide And Its Nanocapsulated Form Onduckweed As A Model Macrophyte, Samaneh Torbati, Mehdi Mahmoudian, Neda Alimirzaei
Turkish Journal of Chemistry
In the present study the nanocapsulation of Haloxyfop-R-methyl in poly(methyl methacrylate) was success- fully performed. Poly(methyl methacrylate)/Haloxyfop-R-methyl nanocapsules were synthesized using a miniemulsion method and their surface morphology was studied by scanning electron microscopy and transition electron microscopy. The chemical characterization of nanocapsules was done by FT-IR spectroscopy. The herbicide loading and encap- sulation efficiency were also analyzed for the herbicide-loaded nanocapsules. In order to evaluate the toxic effects of nanocapsulated herbicide and pure herbicide on Lemna minor L., some physiological effects of these two compounds were investigated. The plant growth rate, photosynthetic pigment contents, and activities of antioxidant enzymes …
Simultaneous Determination Of Azithromycin And Levooxacin In Pharmaceuticalsby Charge Transfer Complexation With Alizarin Red S Using An Absorption-Factormethod, Vijay D. Chavada, Nejal M. Bhatt, Mallika Sanyal, Pranav S. Shrivastav
Simultaneous Determination Of Azithromycin And Levooxacin In Pharmaceuticalsby Charge Transfer Complexation With Alizarin Red S Using An Absorption-Factormethod, Vijay D. Chavada, Nejal M. Bhatt, Mallika Sanyal, Pranav S. Shrivastav
Turkish Journal of Chemistry
A new approach based on a selective charge transfer reaction with alizarin red S is described for the simultaneous determination of azithromycin and levo oxacin in their binary mixtures using an absorption-factor spectrophotometric method. Native absorbance was used for the determination for levo oxacin, while a charge transfer complexation of alizarin red S served as the basis for the quantitation of azithromycin. The reaction of azithromycin with alizarin red S was possible in methanol under neutral conditions within 15 min at 25 ℃. The conditions were suitably optimized for selective complexation of azithromycin with minimal interference from levo oxacin. The …
Physicochemical Characterization Of A Polymeric Conductor: Application To Defluoridation Of Industrial Effluent By Electrodialysis, Maroua Arfaoui, Ali Ouejhani, Bechir Hamrouni
Physicochemical Characterization Of A Polymeric Conductor: Application To Defluoridation Of Industrial Effluent By Electrodialysis, Maroua Arfaoui, Ali Ouejhani, Bechir Hamrouni
Turkish Journal of Chemistry
In many places around the world, the uoride concentration in ground water as raw water is higher than the threshold standard for healthy drinking water. The aim of this work is to study the characteristics of an anionic membrane that will be the subject of an application for de uoridation by electrodialysis. The first objective of this work is to evaluate the physicochemical characteristics of the membrane used in experiments by determination of the exchange capacity, water uptake, ionic conductivity, and transport number (Hittorf method). The second part consists of studying the effect of different parameters such as electrodialysis time, …
Synthesis And Some Optical Results Of Long Chain Substituted Phthalocyanines, İbrahi̇m Özçeşmeci̇, İdri̇s Sorar
Synthesis And Some Optical Results Of Long Chain Substituted Phthalocyanines, İbrahi̇m Özçeşmeci̇, İdri̇s Sorar
Turkish Journal of Chemistry
Four metallo (zinc, copper, vanadyl, and indium) phthalocyanine derivatives bearing four aliphatic (hexylthio) groups were prepared from corresponding phthalonitrile compounds. The metallophthalocyanines were characterized with ultraviolet–visible spectroscopy (UV-Vis), proton nuclear magnetic resonance (1H NMR), Fourier transform-infrared spectroscopy (FT-IR), and mass and elemental analyses techniques. Aggregation properties of metallophthalocyanines in solution were studied in varied concentration ranges. Thin films of metallophthalocyanines were obtained by spin coating technique. Optical measurements showed that transmittance values of metallophthalocyanine thin films obviously changed with respect to the metal ion in the phthalocyanines. Transmittance spectra of the phthalocyanines synthesized using different metal ions showed a variation …
Experimental And Theoretical Studies Of Carbazole-Based Schiff Base As A Fluorescent Fe$^{3+}$ Probe, Hakan Kandemi̇r, Abdulkadi̇r Koçak, Süreyya Oğuz Tümay, Bünyemi̇n Çoşut, Yunus Zorlu, İbrahi̇m Fazil Şengül
Experimental And Theoretical Studies Of Carbazole-Based Schiff Base As A Fluorescent Fe$^{3+}$ Probe, Hakan Kandemi̇r, Abdulkadi̇r Koçak, Süreyya Oğuz Tümay, Bünyemi̇n Çoşut, Yunus Zorlu, İbrahi̇m Fazil Şengül
Turkish Journal of Chemistry
Synthesis of a new (E)-N1-((9-ethyl-9H-carbazol-3-yl)methylene)-5-nitrobenzene-1,2-diamine as a fluorescent chemosensor for selective detection of Fe$^{3+}$ ion over a number of other metal ions is described. The method for the synthesis of the carbazole Schiff base was based on the condensation of carbazole-3-carbaldehyde with 4-nitro-o-phenyldiamine in dimethylformamide in a moderate yield. The structure of the final compound was characterized by $^{1}$H NMR, $^{13}$C NMR, IR, mass spectrometry, and single crystal X-ray diffraction. The final compound exhibited exceptional selective and sensitive turn-on fluorescence response to the Fe$^{3+}$ cation. The fluorescent intensity of the final compound was increased 20-fold and the stoichiometry ratio of …
Voltammetric Determination Of Vanillin In Commercial Food Products Using Overoxidized Poly(Pyrrole) Film-Modified Glassy Carbon Electrodes, Şükri̇ye Ulubay Karabi̇beroğlu, Çağri Ceylan Koçak
Voltammetric Determination Of Vanillin In Commercial Food Products Using Overoxidized Poly(Pyrrole) Film-Modified Glassy Carbon Electrodes, Şükri̇ye Ulubay Karabi̇beroğlu, Çağri Ceylan Koçak
Turkish Journal of Chemistry
In this work, a very simple, rapid, cheap, sensitive, and selective polymer film-modified electrode for vanillin determination in commercial food products was developed via electrochemical polymerization and overoxidation of pyrrole. The formation of both poly(pyrrole) and overoxidized poly(pyrrole) films on a glassy carbon electrode surface was characterized by electrochemical impedance spectroscopy, scanning electron microscopy, and X-ray photoelectron spectroscopy. Under optimized conditions, the calibration graph comprises two linear segments of 0.032-1.500 $\mu $mol L$^{-1}$ and 3.00--150.00 $\mu $mol L$^{-1}$ with a detection limit of 0.012 $\mu $mol L$^{-1}$. The selectivity of the modified electrode was examined in the presence of metals, …
Synthesis And Biological Properties Of Novel1-Methyl-2-(2-(Prop-2-Yn-1-Yloxy)Benzylidene) Hydrazine Analogues, Ari̇f Kivrak, Can Yilmaz, Meti̇n Konuş, Hali̇l Koca, Selahatti̇n Aydemi̇r, Jeger Ali Oagaz
Synthesis And Biological Properties Of Novel1-Methyl-2-(2-(Prop-2-Yn-1-Yloxy)Benzylidene) Hydrazine Analogues, Ari̇f Kivrak, Can Yilmaz, Meti̇n Konuş, Hali̇l Koca, Selahatti̇n Aydemi̇r, Jeger Ali Oagaz
Turkish Journal of Chemistry
1-Methyl-2-(2-(prop-2-yn-1-yloxy)benzylidene)hydrazine analogues were readily prepared in good yields by the reaction of 2-(prop-2-yn-1-yloxy)benzaldehydes and methyl hydrazine. The reaction tolerates a variety of substituents on the 2-hydroxybenzaldehyde to form nitro-, halo-, methoxy-, and naphthyl-substituted 1-methyl-2-(2-(prop-2-yn-1-yloxy)benzylidene)hydrazines. The in vitro antioxidant capacity measurements revealed that among all the analyzed hydrazine analogues that surpassed the Trolox standard, 1-(2-(but-3-ynyl)-5-nitrobenzylidene)-2-methylhydrazine had the maximum value, which was approximately 1.7 times that of Trolox.
Effect Of Ph And $\Beta$-Cyclodextrin On The Photophysical Properties Of Lamotrigine, Raed Ghanem, Fakhri Yousef, Omar Abu Awwad
Effect Of Ph And $\Beta$-Cyclodextrin On The Photophysical Properties Of Lamotrigine, Raed Ghanem, Fakhri Yousef, Omar Abu Awwad
Turkish Journal of Chemistry
Photophysical properties of lamotrigine (LMT) were investigated at different pH values. Lamotrigine exhibited a broad absorption band at 308 nm that was shifted to 268 nm at pH 2.0 due to protonation (HLMT$+)$. Emission spectra of LMT at different pH values showed a single band at 483 nm except for at pH 2.0, where a second band at 502 nm was observed due to the deprotonation from the singlet excited state. LMT pH profile was used to calculate p$K$a of LMT in excited and ground states (p$K$a* $=$ 4.50 and p$K$a $=$ 5.90). Absorption spectra of LMT at different pH …
Nickel(Ii)-Pph$_{3}$ Complexes With Ons And Onn Chelating Thiosemicarbazones: Synthesis And Inhibition Potential On Influenza A Viruses, Şükri̇ye Güveli̇, Kadi̇r Turan, Bahri̇ Ülküseven
Nickel(Ii)-Pph$_{3}$ Complexes With Ons And Onn Chelating Thiosemicarbazones: Synthesis And Inhibition Potential On Influenza A Viruses, Şükri̇ye Güveli̇, Kadi̇r Turan, Bahri̇ Ülküseven
Turkish Journal of Chemistry
Tetra-coordinated nickel(II) complexes of two ONS (1, \2) and seven ONN (3a-3g) chelating 2-hydroxy-3-methoxy-benzaldehyde thiosemicarbazones were synthesized. The dibasic ligands and complexes bearing PPh$_{3}$ as a coligand were characterized by means of analytical and spectroscopic data. Cytotoxic activities of the ligands and nickel(II) complexes were determined using the MTT assay in vitro against MDCK cells, and then all the compounds were tested on influenza virus replication by plaque assays. The compounds showed GI$_{50}$ values varying from concentrations of 15.9 up to 161.8 $\mu$ g/mL for MDCK cells. The plaque assays indicated that one ONS (1) and two ONN (3c and …
Protein Ion-Exchange Chromatography On A Biomacromolecule-Immobilized Monolithic Cryogel, Ahmet Eren Özkan, Idris Guven, Orhan Gezici
Protein Ion-Exchange Chromatography On A Biomacromolecule-Immobilized Monolithic Cryogel, Ahmet Eren Özkan, Idris Guven, Orhan Gezici
Turkish Journal of Chemistry
An efficient and inexpensive monolithic stationary phase (PHEMA-HA) has been prepared through an easy process comprising addition of humic acid (HA) to a mixture of 2-hydroxyethyl methacrylate (HEMA) and N,N'-methylenebisacrylamide (MBAAm) and subsequent radical-polymerization at -20 $^{\circ}$C. The prepared monolithic material was characterized in terms of various techniques and methods such as elemental analysis, FTIR spectroscopy, scanning electron microscopy, mercury porosimetry, hydrolytic stability tests, pH$_{pzc}$ measurements, water-holding capacity, and water permeability. The amount of HA incorporated into the structure was calculated as 45 mg/g from the elemental analysis results. The study was conceptualized on the basis of protein ion-exchange chromatography, …
Sodium Borohydride For The Near-Future Energy: A ''Rough Diamond'' For Turkey, Ümi̇t Bi̇lge Demi̇rci̇
Sodium Borohydride For The Near-Future Energy: A ''Rough Diamond'' For Turkey, Ümi̇t Bi̇lge Demi̇rci̇
Turkish Journal of Chemistry
Boron-based materials are potential solutions in the field of energy. They have been regarded as hydrogen storage materials, liquid fuels of direct liquid-fed fuel cells (DLFCs), electrolytes of battery, and/or energetic substances. A typical example is sodium borohydride (NaBH$_{4}$. In sodium hydroxide-stabilized aqueous solutions, it is seen as an efficient H$_{2}$ generator or a performing fuel of DLFCs. Actually, it plays a wider role; it is also the precursor of several boron-based materials of interest in the field of energy. In other words, it is indirectly considered for other energy applications, i.e. solid electrolytes of all solid-state batteries and hypergolic …
A New Member Of Mo36- Polyoxoanion's Family: Synthesis, Crystal Structure, And Physico-Chemical Properties Of K$_{10}$[Mo$_{36}$O$_{110}$ (Oh)$_{6}$ (H$_{2}$O)$_{12}$].38 H$_{2}$O, Jawaher Baizig, Anissa Haj Abdallah, Amor Haddad
A New Member Of Mo36- Polyoxoanion's Family: Synthesis, Crystal Structure, And Physico-Chemical Properties Of K$_{10}$[Mo$_{36}$O$_{110}$ (Oh)$_{6}$ (H$_{2}$O)$_{12}$].38 H$_{2}$O, Jawaher Baizig, Anissa Haj Abdallah, Amor Haddad
Turkish Journal of Chemistry
The new giant Mo$_{36}$ polyoxomolybdate formulated as K$_{10}$[Mo$_{36}$O$_{110}$(OH)$_{6}$ (H$_{2}$O)$_{12}$].38 H$_{2}$O (1) was isolated by conventional solution method by the reaction of K$_{2}$MoO$_{4}$ and KNO$_{3}$ in aqueous solution (pH = 1.8), at room temperature, and structurally characterized by single-crystal X-ray diffraction methods. The title compound crystallized in the monoclinic system, space group P2$_{1}$/n with unit a = 16.5180 (0) Å, b = 18.4485 (0) Å, c = 24.2424 (0) Å, $\alpha $ = 90.00$^{\circ}$, $\beta $ = 99.51$^{\circ}$, $\gamma $ = 90.00$^{\circ}$, V = 7285.79 (0) Å$^{3}$, and Z = 2. The refinement of the structure led to a residual factor …
Transfer Of The Protonable Surfactant Dipalmitoyl-Phosphatidylcholine Across A Large Liquid/Liquid Interface: A Voltammetric Study, İbrahi̇m Uyanik
Transfer Of The Protonable Surfactant Dipalmitoyl-Phosphatidylcholine Across A Large Liquid/Liquid Interface: A Voltammetric Study, İbrahi̇m Uyanik
Turkish Journal of Chemistry
Adsorption behavior of the zwitterionic phospholipid dipalmitoyl-phosphatidylcholine (DPPC) at the polarizable liquid/liquid interface formed between water and 1,2-dichloroethane electrolyte solutions is studied taking into account both the pH of the aqueous phase and the concentration of the phospholipid in the organic phase by cyclic voltammetry. Experimental results showed that the adsorption of the phospholipid strongly depends on the pH of the aqueous phase, which determines the surface ionization of the polar head of the phospholipid molecule and hence the stability of the adsorbed layer of phospholipids.
Influence Of Manganese Content On The Supercapacitive Performance Of Pbo$_{2}$-Mno$_{2}$ Electrodes, Yingwu Yao, Mengyao Li, Xinghua Zhang, Zunming Lu, Feng Wei
Influence Of Manganese Content On The Supercapacitive Performance Of Pbo$_{2}$-Mno$_{2}$ Electrodes, Yingwu Yao, Mengyao Li, Xinghua Zhang, Zunming Lu, Feng Wei
Turkish Journal of Chemistry
PbO$_{2}$-MnO$_{2}$ electrodes were prepared by electrochemical codeposition methods. The electrodes were characterized by scanning electron microscope, X-ray photoelectron spectroscopy, energy dispersive X-ray spectroscopy, and X-ray diffraction. The content of manganese in the electrodes increased with the increase in manganese ion concentration in the solution, which can reach 48.4%. The codeposition of manganese decreased the grain sizes and formed the porous structure. Cyclic voltammetry and galvanostatic charge-discharge measurements were used to evaluate the influence of manganese content in the electrodes on the specific capacitive performance of PbO$_{2}$-MnO$_{2}$ electrodes. The specific capacitance of PbO$_{2}$-MnO$_{2}$ (48.4%) electrodes could reach 374.5 F g$^{-1}$. The …
The Synthesis Of New Oxindoles As Analogs Of Natural Product 3,3$^\Prime $-Bis(Indolyl)Oxindole And In Vitro Evaluation Of The Enzyme Activity Of G6pd And 6pgd, Si̇nan Bayindir, Adnan Ayna, Yusuf Temel, Mehmet Çi̇ftci̇
The Synthesis Of New Oxindoles As Analogs Of Natural Product 3,3$^\Prime $-Bis(Indolyl)Oxindole And In Vitro Evaluation Of The Enzyme Activity Of G6pd And 6pgd, Si̇nan Bayindir, Adnan Ayna, Yusuf Temel, Mehmet Çi̇ftci̇
Turkish Journal of Chemistry
Natural and synthetic derivatives that contain an indole core are being used in medical treatments and technological processes. Therefore, the development of new synthetic methods for the synthesis of indole derivatives is very popular. In this study, new oxindoles with reaction of 4,7-dihydro-1$H$-indole (2) and isatin (4) were synthesized as analogs of natural product 3,3$^\prime $-bis(indolyl)oxindole. The biological properties of the compounds obtained during this study were also studied, showing that compounds 5, 7, and 12 inhibited the activity of G6PD with an IC$_{50}$ of 99 $\mu $M, 231 $\mu $M, and 304 $\mu $M respectively. The activity of rat …
Oxime-Containing Acetylcholinesterase Reactivators And Their Complexes With Pd(Ii) And Pt(Ii) Ions: Recent Developments, Ivayla Pantcheva, Ahmed Nedzhib, Liudmil Antonov
Oxime-Containing Acetylcholinesterase Reactivators And Their Complexes With Pd(Ii) And Pt(Ii) Ions: Recent Developments, Ivayla Pantcheva, Ahmed Nedzhib, Liudmil Antonov
Turkish Journal of Chemistry
The ability of oxime-containing acetylcholinesterase reactivators BT-07 (K005), BT-08 (K033), BT-07-4M (K074), and obidoxime (H$_{2}$LX$_{2}$, X = Cl$^{-}$, Br$^{-})$ to bind palladium(II) or platinum(II) cations was evaluated in aqueous solutions (pH 7.4) at metal-to-ligand molar ratio varying from 1:10 to 10:1. Spectral changes were monitored within a week after mixing the reagents in the range from 220 nm to 500 nm. Results showed that depending on chemical structure and reaction time, oximes form two complex species of composition, [MHL]$^{3+}$ or [M$_{2}$L]$^{4+}$ (M = Pd(II), Pt(II)). It was also found that complexation of platinum(II) ions proceeds slower as compared to palladium(II). …
Application Of A Pencil Graphite Electrode For Voltammetric Simultaneous Determination Of Ascorbic Acid, Norepinephrine, And Uric Acid In Real Samples, Abdulkadi̇r Levent, Günay Önal
Application Of A Pencil Graphite Electrode For Voltammetric Simultaneous Determination Of Ascorbic Acid, Norepinephrine, And Uric Acid In Real Samples, Abdulkadi̇r Levent, Günay Önal
Turkish Journal of Chemistry
A pencil graphite electrode (PGE) was used for the simultaneous detection of ascorbic acid (AA), norepinephrine (NE), and uric acid (UA) by differential pulse voltammetry and cyclic voltammetry. The anodic peaks of AA, NE, and UA in their mixture can be well separated in 0.1 M Britton--Robinson buffer solution at pH 4.0. The effects of various experimental parameters such as pH, scan rate, and voltammetric parameters on the voltammetric response of these compounds were investigated. Under optimum conditions, linear calibration graphs were obtained from the AA, NE, and UA concentration ranges, which were 100-800 nM, 20-170 nM, and 40-175 nM, …
Adsorptive Properties Of Mesoporous Silica Modified With Lewis Base Molecule And Its Application In The Preconcentration Of Cu(Ii), Co(Ii), And Cd(Ii) From Aqueous Media, Janaíne Do Rócio Ivassechen, Alexandre De Oliveira Jorgetto, Marcos Henrique Pereira Wondracek, Adrielli Cristina Peres Da Silva, Luiz Fabrício Zara, Valber De Albuquerque Pedrosa, Bruno Prior Rocha, Margarida Juri Saeki, Gustavo Rocha Castro
Adsorptive Properties Of Mesoporous Silica Modified With Lewis Base Molecule And Its Application In The Preconcentration Of Cu(Ii), Co(Ii), And Cd(Ii) From Aqueous Media, Janaíne Do Rócio Ivassechen, Alexandre De Oliveira Jorgetto, Marcos Henrique Pereira Wondracek, Adrielli Cristina Peres Da Silva, Luiz Fabrício Zara, Valber De Albuquerque Pedrosa, Bruno Prior Rocha, Margarida Juri Saeki, Gustavo Rocha Castro
Turkish Journal of Chemistry
Cocondensation and postfunctionalization methods were employed to synthesize a mesoporous silica with large surface area (795.1 $\pm $ 1.1 m$^{2}$ g$^{-1})$ modified with 4-amino-5-hydrazino-1,2,4-triazole-3-thiol, which was successfully applied to adsorb and preconcentrate Cu(II), Co(II), and Cd(II) from aqueous media. Infrared spectroscopy of the adsorbent material demonstrated N-H stretching bonds related to primary amines existing in the ligand molecule, elemental analysis revealed the presence of 0.132 mmol g$^{-1}$ of nitrogen, scanning electron microscopy indicated globularly shaped particles with average size of 10 $\mu $m, and the point of zero charge was found to be 7.2. Kinetic data were applied to the …
Removal Of Five Cationic Dyes Using A Resin Coated With Nickel/Nickel Boride Nanoparticles, Merve Çinar, Yasemi̇n İşlek Coşkun, Tüli̇n Deni̇z Çi̇ftçi̇
Removal Of Five Cationic Dyes Using A Resin Coated With Nickel/Nickel Boride Nanoparticles, Merve Çinar, Yasemi̇n İşlek Coşkun, Tüli̇n Deni̇z Çi̇ftçi̇
Turkish Journal of Chemistry
Resins coated with nickel/nickel boride nanoparticles were used to remove brilliant green, methyl violet, methylene blue, phenosafranine, and brilliant cresyl blue from water. The effects of pH, adsorbent dose, contact time, and initial dye concentration on the adsorption efficiencies were investigated. The point of zero charge for the adsorbent was pH 9.5. Isotherm studies were conducted using Langmuir, Freundlich, and Dubinin--Radushkevich models, and thermodynamic studies were also performed. Adsorption of the five dyes was found to obey the Langmuir isotherm model and was endothermic. The maximum adsorption capacities calculated from the Langmuir isotherm were 66.7, 88.5, 144.9, 56.2, and 147.1 …