Digital Commons Network^™

Structural And Functional Insight Of Helicobacter Pylori Translation Initiation Factor If1 (Hpif1) In Protein Biosynthesis And Rational Design Of New Antimicrobial Candidates, Asif Shahriar

Theses and Dissertations

Helicobacter pylori (H. pylori) is a Gram-negative bacterium that colonizes the human gastric mucosa and is associated with peptic ulcer disease and gastric cancer. Bacterial protein synthesis is a fundamental metabolic process occurring in all bacteria and is a validated target of antibiotics; however, the precise structural mechanism of H. pylori protein biosynthesis remains unknown. Protein synthesis contains four stages, and translational initiation is the most important and highly regulated critical step, involving three initiation factors (IF1, IF2, IF3) and other key components. IF1 plays a vital role in regulating this step by binding to the 30S ribosomal subunit cooperatively …

How Can Increased Parental Involvement Facilitate Greater Student Engagement And Academic Success Within One Rgv Middle School, Jaime H. Serna

Theses and Dissertations

The purpose of this study is to explore how can increased parental involvement be encouraged in the K-12 school in the Rio Grande Valley in order to facilitate greater student engagement and academic success. An action research project will be done to explore middle school teachers’ perspectives on parental involvement and the effect it has on student academics. Research will take place in Sunview Middle School were interviews, observations will be conducted to teachers, parental involvement assistant and administrator. Data will assist to improve and promote the parental involvement program to assist all stakeholders and better assist our students.

Geospatial Analysis Based On Hurricane Storm Surge Scenarios On Coastal South Texas And North Mexico, Layda Belia Spor Leal

Theses and Dissertations

The coastal area of the Lower Rio Grande Valley, Texas, and Northern Tamaulipas, Mexico, has historically faced a variety of natural disasters involving flooding hazards, such as hurricanes and tropical storms. These scenarios not only represent imminent danger for the population in the area but can lead to long term effects on the infrastructure located in the impact zone. As such, it is imperative to conduct analysis on not only the specific areas that will be affected, but the severity of flooding that can result after a catastrophic event. Modelling work that simulates the storm surge in case of various …

Red Snapper Abundance, Growth, And Movement At Different Structural Configurations In The Rio Grande Valley Artificial Reef, Marybeth J. Weihbrecht

Theses and Dissertations

The Rio Grande Valley (RGV) artificial reef was built with the goal of providing habitat for reef fish at various life stages. This study used fish trapping to analyze red snapper and grey triggerfish size and abundance in the RGV reef. Mark-recapture of red snapper was utilized to determine growth, movement, and site fidelity within the reef. Nine configurations of patches consisting of varying combinations and densities of concrete pyramids and low-profile modules were surveyed, as well as additional sites of cinder block palettes and concrete railroad ties. Red snapper and triggerfish abundance per trap hour varied significantly by site …

An Investigation Of Standardized Assessment Performance For Middle School Students Before And During The Covid-19 Pandemic, Michael Norman Voth

Theses and Dissertations

The purpose of this study is to examine how the COVID-19 pandemic has affected the learning of students in public education through the analysis of standardized assessment performance before and during COVID-19. The study also compares virtual learning and face-to-face students’ change in performance on the standardized assessments. To answer the research questions, the quantitative research uses 5th and 7th grade math and reading STAAR data from 2019 and 2021 for the same cohort of students at a suburban ISD in Texas. The casual-comparative research study suggests that there is a significant drop in students’ performance on standardized assessments in …

Identifying Direct Foxo Targets Through Chromatin Immunoprecipitation Assays With Sequencing, Alma Lopez

Theses and Dissertations

Glioblastoma Multiforme (GBM) and basal-like breast cancer (BBC) are aggressive cancers associated with poor prognoses. Basal-like breast cancer (BBC) and glioblastoma multiforme (GBM) are poor prognosis cancers that lack effective targeted therapies. A deregulation of FOXOs has been linked to cancer, as they regulate the expression of genes involved in multiple cellular processes. Canonically, the FOXO family of proteins is generally considered tumor suppressors, but evidence suggests that they may be involved in cancer metabolism as well as angiogenesis. Research in our lab has found that these factors play a role in glycolysis and the developmental WNT pathway. Here we …

Teachers’ Perspectives On Multimodal Texts In Middle School Reading Language Arts Classrooms In The Rio Grande Valley, Angelica Montoya Ybarra

Theses and Dissertations

Literacy in the 21st century includes multiple modes of communication that include culturally and linguistic diverse representation. It also includes multimodal texts that use visual, audio, and technological elements to create meaning. The new changing technologies have expanded literacy to more than print and written forms. Literacy instruction has seen pedagogical changes, especially during the COVID-19 pandemic. Educators need to explore new literacy practices that benefit the growing diversity in societies along with the fast-growing technologies. Students need skills and mentoring to navigate digital learning platforms. Literacy in the 21st century includes multimodal texts, technology, nontraditional literacy skills, and multiliteracies. …

Organizational Culture During The Era Of A Black Swan: A Phenomenological Examination Of New Hire Sales Training Within A Medical Diagnostic Company, Maelyn Zweben Lessard

Theses and Dissertations

Traditional sales training in a medical diagnostic organization takes place in multiple locations over the period of many months. New hires attend classes with a set group of other new hire employees establishing a cohort. It is the responsibility of the sales training department and the new hire’s direct supervisor to incorporate training into the organizations culture. This is done by bringing the new hire into the corporate office and, through the months of training, exposing the new hire to leadership, support functions, manufacturing, and multiple departments that will support their job moving forward. COVID-19 created a rapid market increase …

Accident Investigation On In-Flight Loss Of Control Due To Configuration Change On Piper Arrow, Basilio Caruso

Theses and Dissertations

Between 2012 and 2021, NTSB has identified over 2200 accidents due to loss of control. The majority of which happened while flying in the pattern. The most challenging phase of a flight is the take-off and landing. During these phases, the pilot initiates a change of configuration of the airplane by lowering or retracting the flaps. Lowering the flaps slows down the plane and increases the lift of the wing but also changes the longitudinal free response of the aircraft. The pitch changes of the plane require the pilot to promptly compensate to keep straight and level flight and avoid …

A Focus On Followers: Examining Relationships Between Elements Of The Leader-Follower Relationship From The Follower’S Perspective, David James Ross

Theses and Dissertations

This dissertation examines followership style, leadership behaviors, and LMX-quality from the follower’s perspective. This research used Kelley’s followership framework, the full range leadership model, and the LMX-6 instrument to analyze each dimension of the leader-follower relationship. Using a sample of 89 followers from various backgrounds, the study collected data regarding each of the followers’ unique relationships with their leader. These data provided insights into the followers’ current followership style (i.e., their current levels of independent critical thinking and active engagement), their leaders ‘behaviors, and the quality of their individual leader-follower relationship. The researcher used the statistical program JASP to measure …

Flight Test Evaluation Of The B-1b Lancer For The Heavy Bomber Mission, Robert William Gates

Theses and Dissertations

Copyright held by author

Parental Well-Being And Children’S Internalizing Symptoms During The Beginning Of The Covid-19 Pandemic In The United States, Diana Duran

Theses and Dissertations

During the beginning of the COVID-19 pandemic stay-at-home orders in the U.S., many parents of school-age children faced new challenges, such increased child-care demands (Adams, 2021). Prime et al. (2020) theorized these negative pandemic impacts would decrease parents' well-being and thereby impact children's psychological adjustment. This study hypothesized that higher number of negative pandemic impacts would predict worsened stress and relationship satisfaction levels among parents, and that this would in turn predict worsened child internalizing symptoms. 595 U.S. parents of school-age children were recruited online during May 2020. Higher number of negative pandemic impacts predicted worsened parents' stress and relationship …

Evaluating Readiness To Teach Online By Examining The Relationship Between Faculty’S Perceptions Of Importance Of Course Design, Course Communication, Time Management, And Technical Competency, And Their Readiness To Teach Online, Francisco Garcia

Theses and Dissertations

The purpose of this study was to examine faculty’s perceptions of the importance of online teaching competencies and their perceptions of their ability to teach online. Two aspects of readiness are focused on in this framework: 1) faculty attitude on importance of online teaching competencies and 2) faculty perception on their ability to confidently teach online, and four competencies were utilized in this study: Course Design, Course Communication, Time Management, and Technical Competency. A quantitative research design was utilized to analyze data and show the degree of correlation between importance and ability in the four competencies. MANOVA was used to …

Estimating The Functional Consequences Of Intra-Specific Trichome Variation Of Tomato, Solanum Lycopersicum On The Specialist Herbivore, Manduca Sexta, Satinderpal Kaur

Theses and Dissertations

Chapter 1: Plants have a wide array of defenses against herbivores and hence they must confer trade-offs between growth and defense related traits. By using Solanum as a model genus, the major plant defense fitness trade-off hypotheses are reviewed in this chapter along with their assumptions and examples.

Chapter 2: This chapter provides an overview of the enormous intra-specific diversity in trichome morphology in tomato, Solanum lycopersicum. Also, the trichome sub-types are analyzed for the variations in density and dimensions in 10 varieties of tomato by using desktop scanning electron microscope.

Chapter 3: This chapter examines the functional consequences …

Piezoresistivity Of Electrically Conductive Asphalt Concrete, Mateo Schmit Mendoza

Theses and Dissertations

Electrically conductive asphalt concrete is considered as a multifunctional construction material due to its structural and non-structural functions. This study aims to investigate piezoresistivity of conductive asphalt concrete. Piezoresistivity is an electrical property of some materials which electrical resistivity changes with induced strain and subsequently, it has the potential for self-sensing smart technology. Graphite Powder F-516 with various contents was added into the asphalt mixtures to impart the electrical conductivity. Electrochemical impedance spectroscopy (EIS) was selected to measure the electrical properties of the specimens in dry and wet conditions, and low and high temperatures. The impedance measurement shows that the …

Effect Of Brain Injury On Demand Of Alcohol, Whitney Michele Chaney

Theses and Dissertations

Brain injury, or damage to the brain and/or surrounding structures, is listed by the CDC as the leading cause of disability and death in the United States. This kind of injury can result in symptoms that physical, cognitive, and behavioral functioning in those affected. Despite this, current literature reflects a significant deficiency in the understanding and management of behavioral symptoms, that present after the injury, in most neurorehabilitative treatments. This study aimed to investigate whether sustaining a brain injury can effect an individual’s demand intensity for alcohol, if their demand was inelastic, and their probability for misuse of alcohol. To …

Smartphone Video Guidance Sensor In High-Altitude Uav Precision Landing, Joao Leonardo Silva Cotta

Theses and Dissertations

The Smartphone Video Guidance Sensor (SVGS) is an emerging technology developed by NASA Marshall Space Flight Center that uses a vision-based approach to accurately estimate the six-state position and orientation vectors of an illuminated target of known dimensions with respect to a coordinate frame fixed to the camera. SVGS is a software-based sensor that can be deployed using a host platform’s resources (CPU and camera) for proximity operations and formation flight of drones or spacecraft. The SVGS output is calculated based on photogrammetric analysis of the light blobs in each image; its accuracy in linear and angular motion at different …

Results And Simulation Of Active Self-Assembly, Robert M. Alaniz

Theses and Dissertations

Self-assembly is the process by which simple elements in a system organize themselves into more complex structures based on a set of rules that govern their interactions. With many ways to create self-assembling systems, new models of abstraction have also arisen to handle specific mechanisms and procedures. We explore several open problems in the seeded model of Active Self-Assembly, Chemical Reaction Networks, and Surface Chemical Reaction Networks, proving new results while developing a robust simulation environment, AutoTile, to help build and test these results.

Activation Of Opa1 Processing In Differentiated Myoblast Cells, Omar Agustin Carrillo

Theses and Dissertations

Mitochondria are eukaryotic cellular organelles that play a role in energy production, apoptosis, integrated stress response, and aging. Mitochondrial dynamics is the physical fusion (interconnection) and fission (fragmentation) of mitochondria within a cell and tightly regulates mitochondrial functions. Optic atrophy 1 (OPA1) is a dynamin-related GTPase located in the inner mitochondrial membrane, and is responsible for inner mitochondrial membrane fusion. OPA1 exists in five isoforms, the two fusion-active long OPA1 (L-OPA1) and the three fusion-inactive short OPA1 (S-OPA1) isoforms. When the transmembrane potential (∆ψm) is aggravated, the inner membrane metalloprotease OMA1 is activated, causing the complete cleavage of L-OPA1 to …

Evaluation Of Black Holes In An Evolving Universe, John P. Naan

Theses and Dissertations

There are various solutions to the Einstein field equations that represent different physical assumptions, but how to represent multiple black holes within an expanding universe remains an area of open interest. The first step to resolving this question involves evaluating spacetime models that contain a single black hole in an expanding universe. Here, we are primarily interested in understanding the energy distribution of black hole models by solving Einstein's equations using the associated spacetime metric and comparing the propagation of waves within the model against other known spacetime models. Specifically, we will evaluate the combined Schwarschild-de Sitter solution under a …

Near-Optimal Control Of A Quadcopter Using Reinforcement Learning, Alberto Velazquez-Estrada

Theses and Dissertations

This paper presents a novel control method for quadcopters that achieves near-optimal tracking control for input-affine nonlinear quadcopter dynamics. The method uses a reinforcement learning algorithm called Single Network Adaptive Critics (SNAC), which approximates a solution to the discrete-time Hamilton-Jacobi-Bellman (DT-HJB) equation using a single neural network trained offline. The control method involves two SNAC controllers, with the outer loop controlling the linear position and velocities (position control) and the inner loop controlling the angular position and velocities (attitude control). The resulting quadcopter controller provides optimal feedback control and tracks a trajectory for an infinite-horizon, and it is compared with …

A Study To Determine Performance Characteristics Of The Mississippi Cowling - Piper Archer Vs. Piper Warrior, Zilvinas Visockas

Theses and Dissertations

Today, aviation is one of the most technologically advanced and innovative sectors in the world. With fast-depleting natural resources, increasing environmental pollution, and continuous growth in fuel cost, efficiency has become industry’s top priority. Engineers are making gradual improvements that offer overall increase in aircraft’s performance. Drag is critical factor in aviation as it directly impacts aircraft’s fuel efficiency, range, and speed. During the design phase, engineers invest significant effort and expense in attempting to minimize the drag profile by implementing aerodynamic shapes and constantly reducing component weights. One of the real-life examples of such engineering attempts is Piper Archer, …

A Multi-Level Comparison Of Increasing Training Modalities To Train Behavior Analysts To Conduct An Intensive Pediatric Feeding Intervention, Ronald Joseph Clark

Theses and Dissertations

A common focus within behavior analytic clinical practice is to incorporate training with caregivers to promote successful transition of clinical services. In the pediatric feeding literature, for example, training caregivers to ensure maintenance and generalization of the intervention is expected. However, training staff members to provide specific behavioral interventions has received less attention. The current study systematically implemented three levels of training to evaluate the level of intensity required to train behavior analytic staff (i.e., behavior technicians, Registered Behavior Technicians®, and Board-Certified Behavior Analysts®) to implement a feeding protocol with a role play partner. Only one participant met the mastery …

Cfis’ Safety Behaviors At Flight Training Schools: Understanding The Effects Of Personality Traits, Self-Efficacy, Risk Perception, And Safety Climate, Vivek Sharma

Theses and Dissertations

The purpose of the current study was to investigate the relationship between personality traits, affective domain variables, safety climate, and safety behaviors of certified flight instructors (CFIs). Personality traits consisted of the five dimensions of the Big Five personality model, including Extraversion, Neuroticism, Agreeableness, Openness, and Conscientiousness. Affective domain variables included self-efficacy and risk perception. The study used an explanatory correlational design to determine the relationship between the targeted factors and safety behaviors. The dependent variable was CFIs’ safety behaviors. The sample consisted of 134 CFIs who completed all of the study’s protocols. Participants were obtained from a professional flight …

Improving The Learning Efficiency Of Adaptive Optimal Control In Information-Limited Environments, Omar Ghassan Qasem

Theses and Dissertations

This work investigates the adaptive optimal control problems for continuous-time linear and nonlinear systems. A novel adaptive dynamic programming method, namely hybrid iteration (HI) is presented. Different from the existing adaptive dynamic programming methods, i.e., policy iteration (PI) and value iteration (VI), the HI does not require an initial admissible control policy compared to the PI. On the other hand, the HI converges to the optimal control policy in much less learning iterations and CPU time compared to the VI due to the ensured quadratic rate of convergence of the HI method, which is much faster than the sub-linear convergence …

Human Capital Advantage From Fortitude, Resilience, And Perseverance Of Minority Ceos In Stem Organizations: A Phenomenological Study, Torin Mordel Malone

Theses and Dissertations

This research study explored how the inherent lived experiences of minorities can foster the attributes of strength and stamina, collectively referred to as the fortitude, resilience, and perseverance (FRP) of minority executive-level leadership. Specifically, this research considered the lived experiences of ten minority CEOs and assessed the influence of how they lead and communicate within their organizations. The purpose of this qualitative phenomenological study was to discover if and how the attributes of FRP could distinctively serve as a human capital advantage for organizations to consider with regard to utilizing minority executive-level leadership. The implication is that the greater understanding …

Exploring The Role Of Soft Skills Amongst African American Women Navigating Barriers To Achieving Corporate Leadership, Latoya Newell Burke

Theses and Dissertations

This study sought to explore the role of soft skills in African American women's ascension to corporate leadership as they navigate and overcome barriers. The disparity of African American women in corporate leadership is longstanding. African American women's corporate American experience is distinct and often fraught with difficulties. In order to overcome the obstacles they encountered while pursuing executive leadership, this study investigated if soft skills were thought to be a crucial skill required. The study fills a gap in research that addresses African American women specifically. Previous studies have addressed the barriers that African American women face in corporate …

Design And Synthesis Of Novel Peptide-Metal Organic Frameworks, Moustafa Mahmoud Abdel Wahid Hamaad

Theses and Dissertations

Metal-organic frameworks (MOFs) are a class of crystalline porous materials with extended network structures formed through the reticular assembly of inorganic and organic molecular building blocks through strong coordination bonds. Compared to other porous materials, MOFs offer a high degree of structural diversity as their shape and pore size as well as functionality can tuned by the precise selection and design of their metal centers and organic struts. Due to their high surface areas, pore volumes, and the possibility of introduction of a myriad of chemical functionalities in their structures, MOFs have gained popularity for applications in many fields such …

Anti-Doping Crisis In Sports, What's Next? Ion Mobility-Mass Spectrometry For The Study Of Anabolic Androgenic Steroids, Diana Constanza Velosa

Theses and Dissertations

The main objective of this work is to augment both qualitative and quantitative measures of anabolic androgenic steroids (AAS) with ion mobility-mass spectrometry (IM-MS), laying the foundation for implementation into analytical drug testing laboratories. AAS testing requires high sensitivity and specificity. IM-MS is presented as an emerging technology workflow capable of targeted quantification of AAS and structural elucidation for potential unknowns, allowing ions to be separated and characterized based on their rotationally averaged collision cross section (CCS). Chapter 1 provides a background of the basic principles of IMS and the different types of analytical methods used for doping analysis currently …

The Examination Of Factors That Influence Trust In A Multi-Agent Team Context, Cherrise Ficke

Theses and Dissertations

Current dyadic teams in the human-agent teams literature demonstrates that Propensity to Trust in Technology (PTT), previous experience with an agent, levels of autonomy (LOA), workload, and mission performance affect trust and mission performance to some capacity. However, the purpose of this study was to expand this line of research by examining how these factors influence trust and mission performance in a multi unmanned aerial vehicle (UAV) context. To investigate the relationship between these factors and trust, an archival study was conducted using data from a previously-conducted, multi-UAV study. The previous study utilized a within-subjects repeated measures design in which …