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A Systematic Review Of Preferred Practices To Reintegrate Male Opiate Addicts Into Family Relations While In An Evidence-Based Recovery Program, Arkaya Williams-Abbott Jan 2024

A Systematic Review Of Preferred Practices To Reintegrate Male Opiate Addicts Into Family Relations While In An Evidence-Based Recovery Program, Arkaya Williams-Abbott

Theses and Dissertations

Active addiction strains family relationships. The purpose of this study was to conduct a systematic review to determine preferred practices to help reintegrate male opiate addicts into family relations while in an evidence-based recovery program. Twenty-three articles of various methodologies were reviewed. Findings indicated three themes: stigma and men with opioid disorder, how men seek help, and family relationships and role in substance abuse treatment. Findings showed evidence-based programming should ensure training for treatment providers on men’s socialization and how it affects their approach to treatment and lack of willingness to seek help. Effective communication and de-stigmatized language is another …


The School Of SharīʿA Judges: SharīʿA Courts’ Reform And Legal Modernization In Egypt (1907-1927), Yamen Nouh Dec 2023

The School Of SharīʿA Judges: SharīʿA Courts’ Reform And Legal Modernization In Egypt (1907-1927), Yamen Nouh

Theses and Dissertations

This thesis studied the history of the school of sharīʿa judges (1907-1927) as an essential episode of the reform of Sharīʿa courts in Egypt in the early 20th century. The thesis studied the school in connection with the broader context of legal modernization of the Egyptian legal system. The study explored the institutional, pedagogical, and legal aspects of the reform that the school advocated. The study analyzed the impact of the school’s pedagogy on the practice of the Islamic judiciary and the theoretical conception of Sharīʿa. The study used a significant yet understudied historical source: the judicial press. A comparative …


Borophene And Graphene For Non-Enzymatic Biosensor- Ab-Initio Study, Omar A. Ismail Dec 2023

Borophene And Graphene For Non-Enzymatic Biosensor- Ab-Initio Study, Omar A. Ismail

Theses and Dissertations

Non-enzymatic glucose sensing holds promise to overcome limitations associated with glucose oxidase, such as oxygen dependence and short shelf life. This study explores the potential sensing capabilities of borophene and graphene through direct interaction with various compounds, including β-glucose, uric acid, ascorbic acid, fructose, and acetaminophen. Using Density Functional Theory (DFT), we calculated binding energies and the respective Density of States (DOS) for these adsorbates on both graphene and borophene surfaces. Preliminary results suggest that borophene might exhibit nearly twice the affinity for β-glucose compared to graphene. Moreover, the calculated Density of States reveals distinct distortions in the electronic states …


La Incidencia En El Desarrollo De Competencias Digitales De Los Estudiantes De Una Universidad Virtual En Texas, Elga D. Sepulveda Suarez Dec 2023

La Incidencia En El Desarrollo De Competencias Digitales De Los Estudiantes De Una Universidad Virtual En Texas, Elga D. Sepulveda Suarez

Theses and Dissertations

El propósito de este estudio cuantitativo fue indagar en la incidencia en el desarrollo de las competencias digitales de los estudiantes de una universidad virtual en Texas. Durante el mes de marzo del año 2023 se administró un cuestionario a los estudiantes subgraduados con el fin de conocer sobre el desarrollo de las competencias digitales. El estudio reflejó la importancia en buscar herramientas que ayuden a que el estudiante pueda estimular su creatividad, desarrollar su pensamiento crítico y discernir sobre el uso y manejo de herramientas digitales. Esta fue una investigación tuvo un diseño cuantitativo no experimental, tipo transeccional descriptivo. …


Advancing Polymer Sustainability Through Custom Interpenetrating Polymer Network Synthesis, Processing, And Design, Alexandra Maria Lehman-Chong Dec 2023

Advancing Polymer Sustainability Through Custom Interpenetrating Polymer Network Synthesis, Processing, And Design, Alexandra Maria Lehman-Chong

Theses and Dissertations

The need for improving polymer sustainability is as ubiquitous as the role of polymers in modern society. Interpenetrating polymer network (IPN) design flexibility offers opportunities for improved polymer sustainability while balancing desired polymer properties for various applications. This work investigates the structure-property-processing relationships of IPNs judiciously designed under the framework of the polymer life cycle. Sustainable polymer design was largely considered at the feedstock and manufacturing stages while considering overall polymer performance. Chemicals from bio-based feedstocks were used to design a full simultaneous polybenzoxazine-epoxy IPN, focusing on the effects of monomer and polymer structure on polymer properties. Processing-property relationships were …


Fabrication & Characterization Of Hybrid Piezoelectric/Triboelectric Nanocomposite Nanogenerators Via Fusion Deposition Modeling, Khaled El Toukhy Dec 2023

Fabrication & Characterization Of Hybrid Piezoelectric/Triboelectric Nanocomposite Nanogenerators Via Fusion Deposition Modeling, Khaled El Toukhy

Theses and Dissertations

This thesis aims to discuss the potential of using piezoelectric and triboelectric nanogenerators (PTENGs) for energy harvesting, particularly in the sportswear industry. PTENG's main advantage is that it offers good flexibility making it suitable for high-strain applications. The piezoelectric effect is induced by embedding piezoelectric nanofillers into one of the two triboelectric layers. PTENGs can generate both piezoelectric and triboelectric signals when strained resulting in an enhanced output compared to regular piezoelectric nanogenerators (PENGs) and triboelectric nanogenerators (TENGs). TPU was adopted as the matrix for PTENGs advantageous due to their flexibility, low electrical resistivity, and compatibility with additive manufacturing techniques. …


An Inquiry On The Efficacy Of Choice And Preference As Catalysts For The Social And Community Inclusion Of Individuals With Intellectual Disabilities: A Transformative Mixed-Methods Study, Mbuh Godwill Payne Dec 2023

An Inquiry On The Efficacy Of Choice And Preference As Catalysts For The Social And Community Inclusion Of Individuals With Intellectual Disabilities: A Transformative Mixed-Methods Study, Mbuh Godwill Payne

Theses and Dissertations

This dissertation investigates the efficacy of choice and preference as drivers for social and community inclusion among individuals with intellectual disabilities living in supervised apartments. The study unfolds through three distinct stages: Phase 1 - Quantitative, Phase 2 - Qualitative, and Phase 3 - Focus Group Discussions. In the Quantitative Phase, data collection is conducted to lay the foundation for the subsequent Qualitative interviews in Phase 2, which further inform the Focus Group Discussions in Phase 3. The research findings underscore the significance of environmental opportunities and support in facilitating increased social and community inclusion activities among individuals with intellectual …


Investigating Teachers’ Sensemaking Process And Experiences Of Working With Students With Labels Of Autism In Saudi Arabian Public Schools: A Qualitative Collective Case Study, Hind Alharbi Dec 2023

Investigating Teachers’ Sensemaking Process And Experiences Of Working With Students With Labels Of Autism In Saudi Arabian Public Schools: A Qualitative Collective Case Study, Hind Alharbi

Theses and Dissertations

In this dissertation, I conducted a collective qualitative case study to understand the personal experiences and sensemaking processes that teachers developed to educate students with labels of autism in inclusion settings in Riyadh public schools. Specifically, I aimed to understand how teachers’ attitudes, beliefs, and knowledge regarding the inclusion of autistic students explained why teachers did what they did in their school context. In three rounds of semistructured interviews with eight teachers, participants explained their experiences and process of teaching students with autism. Participants also shared documents and artifacts to provide a deeper understanding of the nature of inclusion offered …


A Case For The Negotiation Of Agency By Disenfranchised Subjects In Contemporary Nigerian Literature, Chinelo Eneh Dec 2023

A Case For The Negotiation Of Agency By Disenfranchised Subjects In Contemporary Nigerian Literature, Chinelo Eneh

Theses and Dissertations

This thesis diverges from conventional narratives that predominantly focus on the challenges faced by women and children in Nigeria, particularly in the aftermath of colonial rule. While existing scholarship tends to underscore the myriad difficulties and constraints experienced by these individuals, this study takes a departure from such well-trodden paths. Instead, it endeavors to bring to the forefront the endeavors undertaken by these subjects to assert a measure of agency and autonomy, specifically during two tumultuous periods in Nigeria's history. Through a focused examination of Chimamanda Adichie's "Half of A Yellow Sun" and Adaobi Nwaubani's "Buried Beneath the Baobab Tree," …


Unlocking The Potential Of Earned Value Management In Construction: A Comparative Study, Mohamed Elsaid Dec 2023

Unlocking The Potential Of Earned Value Management In Construction: A Comparative Study, Mohamed Elsaid

Theses and Dissertations

The implementation of earned value management (EVM) in the construction industry faces challenges when it comes to application, accuracy, and interpretability of results, with potential enhancements yet to be realized. In light of technological advancements, there is an opportunity to develop a controlled EVM approach for improved project management. The goal of this research is to enhance the application and accuracy of earned value techniques in Egyptian construction projects through a comprehensive evaluation of Earned Duration, Earned Schedule, and Planned Value methods. The key challenge that is addressed in this research lies in selecting an optimal technique considering the variations …


Inference Methods For Token-Level Topic Assignments With Fixed Topics, Stephen Cowley Dec 2023

Inference Methods For Token-Level Topic Assignments With Fixed Topics, Stephen Cowley

Theses and Dissertations

Topic modeling, an unsupervised technique used to gain high-level understanding of a large collection of documents, often involves two major goals: The discovery of topics used in the corpus (topic-discovery) and the assignment of topics to individual words (token-level topic assignment). While Latent Dirichlet Allocation (LDA) normally performs both of these steps simultaneously, some situations require only the token-level topic assignments, using fixed topics. We evaluate three topic assignment strategies using fixed topics -- Gibbs sampling, iterated conditional modes, and mean field variational inference -- to determine which should be used when only token-level topic assignment is needed. Among these …


The Fineview Dataset: A 3d Scanned Multi-View Object Dataset Of Fine-Grained Category Instances, Suguru Onda Dec 2023

The Fineview Dataset: A 3d Scanned Multi-View Object Dataset Of Fine-Grained Category Instances, Suguru Onda

Theses and Dissertations

In the past decade state-of-the-art deep learning models have shown impressive performance in many computer vision tasks by learning from large and diverse image datasets. Most of these datasets consist of web-scraped image collections. This approach, however, makes it very challenging to obtain desirable data such as multiple views of the same object, 3D geometric information, or camera parameters for a large-scale image dataset. In this paper, we propose a 3D-scanned multi-view 2D image dataset of fine-grained category instances with accurate camera calibration parameters. We describe our bi-directional, multi-camera and 3D scanning system and the data collection pipeline. Our target …


Your Mission, Should You Choose To Attempt It, Is To Save The Mona Lisa! Gamification As A Method For Teaching Art, Caleb Ovard Dec 2023

Your Mission, Should You Choose To Attempt It, Is To Save The Mona Lisa! Gamification As A Method For Teaching Art, Caleb Ovard

Theses and Dissertations

To increase student engagement in their classroom, the author created an art curriculum using gamification methods that incorporates elements of tabletop role-playing games. The Role-playing Art Curriculum is a key element of this thesis. Possible research approaches involving game-based learning and gamification were examined to point toward future research and reflection regarding games and game-like content into an art curriculum. Action research methods were used to create and run the Role-playing Art Curriculum. The author concludes that the gamified curriculum took extra preparation and required more management to run then other traditional art curriculums.


Harnessing The Power Of Student Voice: A Case Study Of Hybrid Proficiency-Based And Co-Created Curriculum And Assessment, Kaitlyn A. Seamons Dec 2023

Harnessing The Power Of Student Voice: A Case Study Of Hybrid Proficiency-Based And Co-Created Curriculum And Assessment, Kaitlyn A. Seamons

Theses and Dissertations

Assessment has become a dirty word in arts education, because art is notoriously difficult to assess. Assessment, which is often disliked or even disavowed by arts educators, due to its history of incompatibility with the idiosyncratic nature of arts learning, should ideally be utilized as a means of measuring student progress and help teachers understand how to help students succeed. While assessment can also be used to evaluate programs and teachers and to compare student successes relative to those of other students, I will be focusing on measuring individual student progress for my thesis and building a curriculum to support …


A Systems Approach To Process Design And Sustainability - Synergy Via Pollution Prevention, Control, And Source Reduction, Emmanuel Apau Aboagye Dec 2023

A Systems Approach To Process Design And Sustainability - Synergy Via Pollution Prevention, Control, And Source Reduction, Emmanuel Apau Aboagye

Theses and Dissertations

Historically, process design prioritized efficiency and profitability, often overlooking environmental and societal implications. However, given the global challenges like climate change and resource scarcity, there is a growing emphasis on embedding sustainability into process design. Adopting a systems-oriented approach provides a comprehensive view, spanning from raw material acquisition to end-of-life product management. Such an approach not only identifies potential sustainability challenges but ensures that solutions foster both environmental responsibility and economic viability. In this study, a comprehensive framework for designing industrial systems is introduced, aiming to encompass the entire lifecycle impacts of chemical processes. The research initially delves into two …


An Advanced Sensor Network To Calculate Net Unit Heat Rate Of A Coal-Fired Boiler In Real-Time For Use In Dynamic Optimization, Keane Christopher Stewart Dec 2023

An Advanced Sensor Network To Calculate Net Unit Heat Rate Of A Coal-Fired Boiler In Real-Time For Use In Dynamic Optimization, Keane Christopher Stewart

Theses and Dissertations

Dynamic operation of dispatchable energy sources is crucial for enabling the efficient integration of intermittent renewable energy into the electricity grid. Coal-fired boilers have been required to increase transient operation as renewable energy expands in order to avoid excess renewable energy going to waste. The frequent transient operation required to meet residual energy demand has created a challenge for coal-fired units to operate efficiently. This work utilizes an Advanced Sensor Network (ASN) to calculate Net Unit Heat Rate (NUHR) of a coal-fired boiler in real time through combustion calculations and statistical correlations to provide the tools for optimizing dynamic operation. …


Synthesis And Characterization Of Porphyrin And Phthalocyanine-Based Photosensitizers For Energy And Biomedical Applications, Mavis Forson Dec 2023

Synthesis And Characterization Of Porphyrin And Phthalocyanine-Based Photosensitizers For Energy And Biomedical Applications, Mavis Forson

Theses and Dissertations

Porphyrins have been widely used as photosensitizers in research due to their important role in many biological processes. Phthalocyanines have also gained interest in biological applications such as photodynamic therapy (PDT). This dissertation is focused on the synthesis of different photosensitizers for various applications. This dissertation's first section focuses on research involving synthesizing covalently bonded donor-acceptor systems as photosensitizers. Specifically in this work, two porphyrin-fullerene dyads were synthesized using a modified tetraphenyl porphyrin with varying bridges between the porphyrin and fullerene. Metal was incorporated in the porphyrin core to enhance the properties of the dyads as photosensitizers. Detailed photophysical properties, …


Improving The Quality Of Micronutrient Food Composition Data In Sub-Saharan Africa Using Predictive Analytics, Junior Mbuyamba Muka Dec 2023

Improving The Quality Of Micronutrient Food Composition Data In Sub-Saharan Africa Using Predictive Analytics, Junior Mbuyamba Muka

Theses and Dissertations

High-quality food composition data are indispensable for decision making in several health, agricultural, and nutrition-related activities. Analytical data are the most accurate type of food composition data (FCD). Yet, most food composition databases (FCDBs) compiled in Sub-Saharan Africa only contain a small amount of analytical data collected from foods consumed in this region. Most of the data are either borrowed / copied from FCDBs collected in other parts of the world, calculated, imputed, or presumed data. Even with these alternative types, FCDBs in Sub-Saharan Africa have not reached a satisfactory level of completeness, as they still have missing data for …


Understanding The Origin, Evolution, And Dynamics Of Transneptunian Binaries, Benjamin C N Proudfoot Dec 2023

Understanding The Origin, Evolution, And Dynamics Of Transneptunian Binaries, Benjamin C N Proudfoot

Theses and Dissertations

This dissertation discusses research that focuses on understanding transneptunian objects (TNOs) using a variety of techniques and approaches. In Chapter 1, I introduce the main concepts used throughout this dissertation and discuss the current understanding of the transneptunian region. In Chapter 2, I discuss my efforts to understand how Neptune's late stages of migration affect the Haumea family, the only known collisional family in the transneptunian region. Using advanced simulations of Neptune migration, I find that the Haumea family can plausibly form before the termination of giant planet migration and show that this extensively mixes the family. The simplest explanation …


Progress Towards The Development Of Asymmetric Conditions For Intramolecular Heteroatom/Dehydro-Diels-Alder Reactions For Synthesizing Furo[3,4-C] Pyranones And Anticancer Podophyllotoxins, Peter Mpaata Dec 2023

Progress Towards The Development Of Asymmetric Conditions For Intramolecular Heteroatom/Dehydro-Diels-Alder Reactions For Synthesizing Furo[3,4-C] Pyranones And Anticancer Podophyllotoxins, Peter Mpaata

Theses and Dissertations

Furo[3,4-c] pyranone is a unique bicyclic molecular structure found in bioactive sesquiterpene isobolivianine and in artificial cytotoxic stilbene derivatives. The structure of furo[3,4-c] pyranone is analogous to cyclopenta[c] pyran structure found in potent cytotoxic iridoids like catapol. Chiral substrates for intramolecular hetero-Diels-Alder (IHDA) reaction have been synthesized in yields ranging from 39% to 81%. These compounds undergo [4+2] cycloaddition via ambimodal/ bispericyclic process to give a mixture of furo[3,4-c] pyranone in yields ranging 40-70% and aryl tetralin lactone derivatives. Density functional theory (DFT) calculations have been performed to gain insight into the mechanism leading to the formation of these compounds. …


Investigating The Geochemical Trends At The Sediment-Water Interface Of The Shallow And Eutrophic Utah Lake, Abidemi Sherif Aremu Dec 2023

Investigating The Geochemical Trends At The Sediment-Water Interface Of The Shallow And Eutrophic Utah Lake, Abidemi Sherif Aremu

Theses and Dissertations

The sources of phosphorus (P) in Utah Lake can be diverse, including natural and anthropogenic point and non-point sources, such as atmospheric deposition, soil erosion, and industrial and urban wastewater effluents. This study collected interface sediments, column water, porewater, and sediment cores across this vast water body. These samples were then analyzed for their mineralogic, organic, and elemental composition to characterize the geochemical nature of water and sediment at the water-sediment interface within Utah Lake. The average concentrations of P and other elements found in the column water of an individual site do not significantly differ across depth suggesting Utah …


Predicting Speaking Proficiency With Fluency Features Using Machine Learning, Ethan D. Erickson Dec 2023

Predicting Speaking Proficiency With Fluency Features Using Machine Learning, Ethan D. Erickson

Theses and Dissertations

This study investigates the interplay between temporal fluency measures, self-assessment, and language proficiency scores in novice- to intermediate- level language learners of Spanish and French. Analyzing data from 163 participants, the research employs both traditional linear regression and advanced XGBoost machine learning models. Findings demonstrate a moderate positive correlation between self-assessment and Oral Proficiency Interview by Computer (OPIc) scores, underscoring the dependable self-awareness of learners. Notably, XGBoost performs as well as linear regression in predicting OPIc scores and has more potential, underlining the efficacy of advanced methodologies. The study identifies Mean Length of Utterance (MLU) as a crucial predictor, highlighting …


Optimal Method To Obtain Soil Strength Properties In Sands For Laterally Loaded Pile Analysis In Lpile, Troy Roger Washburn Dec 2023

Optimal Method To Obtain Soil Strength Properties In Sands For Laterally Loaded Pile Analysis In Lpile, Troy Roger Washburn

Theses and Dissertations

One common software program developed for analyzing single laterally loaded piles is called LPILE. Soil properties are required as input into LPILE. For sands, the soil properties required are effective soil unit weight, γ’; subgrade modulus, k; and the internal friction angle, ϕ’. There are two commonly used methods to obtain ϕ’ and subsequently k: the API method and Bolton method. Fourteen different pile test sites were used in the analysis of the API and Bolton methods to obtain soil strength properties in sands for laterally loaded single pile tests. Between the fourteen pile test sites, a total of 26 …


Local Atomic And Magnetic Structure Of Multiferroic (Sr,Ba)(Mn,Ti)O3, Braedon Jones Dec 2023

Local Atomic And Magnetic Structure Of Multiferroic (Sr,Ba)(Mn,Ti)O3, Braedon Jones

Theses and Dissertations

We present a detailed study of the local atomic and magnetic structure of the type-I multiferroic perovskite system (Sr,Ba)(Mn,Ti)O3 using x-ray and neutron pair distribution function (PDF) analysis, polarized neutron scattering, and muon spin relaxation (μSR) techniques. The atomic PDF analysis reveals widespread nanoscale tetragonal distortions of the crystal structure even in the paraelectric phase with average cubic symmetry, corresponding to incipient ferroelectricity in the local structure. Magnetic PDF analysis, polarized neutron scattering, and μSR likewise confirm the presence of short-range antiferromagnetic correlations in the paramagnetic state, which grow in magnitude as the temperature approaches the magnetic transition. We show …


Mechanical Characterization Of Vertically Aligned Carbon Nanotube Forest Microelectrodes For Neural Interfacing, Spencer Mcleod Roberts Dec 2023

Mechanical Characterization Of Vertically Aligned Carbon Nanotube Forest Microelectrodes For Neural Interfacing, Spencer Mcleod Roberts

Theses and Dissertations

Silicon intracortical microelectrodes arrays (MEA) provide some of the best performance for brain computer interfaces but suffer from lifetime limitations that prevent clinical adoption. A primary contributor of lifetime limitations is the chronic foreign body response (FBR) which remains active in response to the brain tissue strain caused by implanted probes during brain micromotion. Designing probes with softer materials can reduce the chronic FBR and improve device lifetime. A high-aspect ratio CNT MEA could provide several advantages as an intracortical MEA but has yet to be mechanically characterized. CNT MEAs are infiltrated with 3 degrees of carbon infiltration and mechanically …


Motives And Methodologies For Improving 3d Displays, Dylan Charles Barton Dec 2023

Motives And Methodologies For Improving 3d Displays, Dylan Charles Barton

Theses and Dissertations

This work contains two key contributions to the development of 3D displays. First a successful exploratory human trial research study. By comparing multiple real displays in human trials, the factors of ease of use, time, and accuracy were able to be examined in a general setting, instead of isolated to only a specific type of 3D display. These human tests showed that 3D displays in general offer better ease of use and accuracy compared to 2D displays when showing 3D media. This differs from previous studies where only a single display was examined or theoretical papers discussing factors on paper. …


Simulating Government Institutions In Networked Societies, Michael Richards Dec 2023

Simulating Government Institutions In Networked Societies, Michael Richards

Theses and Dissertations

Modern human societies give rise to the expression of complex group dynamics between the members of said society due to the abundance of continued interactions. Of particular interest are how institutions affect these interactions between societal members, alter the resulting group dynamics, and impact society as a whole through their rules. Simulating these dynamics allows for greater insight into how these institutions function and allows researchers to pose interesting questions and test hypotheses within a laboratory setting. We present a novel approach to simulating institutions, particularly governments, within a networked society. This approach builds upon the Junior High Game, which …


Characterization Of Friction At The Tool/Material Interface In Friction Stir Welding, Bryan Gonzalo Ramos Gonzales Dec 2023

Characterization Of Friction At The Tool/Material Interface In Friction Stir Welding, Bryan Gonzalo Ramos Gonzales

Theses and Dissertations

Friction Stir Welding (FSW) process development is very costly, and it is still experimental. A predictive model would optimize the weld by changing parameters and obtaining results that reflect the physical process. Friction is the primary adjustable parameter in FSW modeling. Currently, friction model selection is not physic-based. It is based on what is available and contributes to the best fit between the model and experimental data. The research objective is to characterize the interface tool/base material by studying the effect of tool friction coefficient and thermal properties. This is accomplished by changing welding parameters such as force, rpm, and …


Bridging The Gaps: Characterizing Alzheimer's Disease In Native Hawaiian And Pacific Islander Populations, Justina P. Tavana Dec 2023

Bridging The Gaps: Characterizing Alzheimer's Disease In Native Hawaiian And Pacific Islander Populations, Justina P. Tavana

Theses and Dissertations

This dissertation addresses critical gaps in dementia research in Native Hawaiian and Pacific Islander (NHPI) communities. Focusing on Samoan and Tongan communities, the study successfully adapted and validated the AD8 informant interview and the Clinical Dementia Rating (CDR) scale in native languages, establishing these instruments as reliable tools for detecting cognitive impairment in these populations. The research process prioritized meaningful community engagement and forged partnerships with indigenous professionals, ensuring alignment with and responsiveness to the specific needs of the community. These invaluable connections were the foundation of making this difficult work possible. Subjects assessed with these adapted instruments were enrolled …


Optimal Control Of Ion Exchange Process For Chromate Removal And Protein A Chromatography For Antibody Extraction, Fadi Ghanem Dec 2023

Optimal Control Of Ion Exchange Process For Chromate Removal And Protein A Chromatography For Antibody Extraction, Fadi Ghanem

Theses and Dissertations

Ion exchange resins are widely used in the extraction of hazardous chemicals as well as the recovery of precious molecules. Therefore, an early breakthrough from the resin system can lead to toxic compounds affecting the drinking water quality or inefficient use of costly resins. Hence, accurate modeling of the ion exchange process and control strategy can enable decisions that assist in avoiding leakage when facing fluctuations in the inlet contaminant concentrations. In this work, the ion exchange process is modeled via the method of moments where the system uncertainties are captured via stochastic modeling using Ito processes. The flow rate …