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Engineered Peptide Biomaterials And Synthetic Transmembrane Receptors For Native And Programmable Cell Interactions, Matthias Recktenwald Jun 2025

Engineered Peptide Biomaterials And Synthetic Transmembrane Receptors For Native And Programmable Cell Interactions, Matthias Recktenwald

Theses and Dissertations

Peptide-functionalized biomaterials enable cell-material interactions through peptide-induced activation of native and synthetic receptors. This dissertation expands the clinical potential of biomaterials by harnessing native and synthetic receptor-peptide interactions. Key advancements include: (1) developing a novel method to functionalize rigid biomaterials with peptides, (2) designing antimicrobial peptide-modified hydrogels and plastics, (3) functionalizing hydrogels with N-cadherin peptides to improve stem cell manufacturing, and (4) engineering synthetic mammalian transmembrane receptors that initiate non-native intracellular responses to peptide-ligands. Using thiol-norbornene click chemistry, we functionalized rigid plastics and soft hydrogels using therapeutic peptides with spatial and temporal control. While advances in synthetic biology have enabled …

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New Student Orientation Programs: Understanding The Perceptions And Experiences Of First-Generation Community College Students, April J. Catching Jun 2025

New Student Orientation Programs: Understanding The Perceptions And Experiences Of First-Generation Community College Students, April J. Catching

Theses and Dissertations

This study examines first-generation community college students' perceptions of New Student Orientation programs. The research questions focus on specific aspects of students' experiences and transitions to gain an understanding of their perspectives. The objective is to see if there is a connection between what researchers ascertain are the most valuable experiences for new students and what students feel and perceive while enrolled in their first semester of college. Qualitative data was collected to provide targeted insights for improving orientation programs and practices. The research questions focused on understanding specific aspects of students’ orientation experiences and their impact on their college …

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Can Social And Emotional Lessons Improve Student Behavior In A First Grade Classroom? A Program Evaluation, Tara Freeman Mozee Jun 2025

Can Social And Emotional Lessons Improve Student Behavior In A First Grade Classroom? A Program Evaluation, Tara Freeman Mozee

Theses and Dissertations

This program evaluation discusses how using a social and emotional (SEL) curriculum taught first-grade students how to manage and regulate their behavior in a first-grade classroom. The purpose of this program evaluation was to evaluate if the SEL curriculum helped first-grade students manage and regulate their behavior in the classroom so the teacher would create fewer behavior management plans and spend more time on classroom instruction. The methodology used in this program evaluation was a logic model. This model presented the inputs, activities, outputs, and outcomes of the program evaluation. The implications of this program evaluation are based on the …

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Enhancing Gpr Reliability For Concrete Infrastructure: Integrating Signal Processing And Deep Learning For Defect And Corrosion Assessment, Priyam Chowdhury Jun 2025

Enhancing Gpr Reliability For Concrete Infrastructure: Integrating Signal Processing And Deep Learning For Defect And Corrosion Assessment, Priyam Chowdhury

Theses and Dissertations

This research addresses the critical issue of deteriorating civil infrastructure by utilizing GPR integrated with advanced signal processing and machine learning. Employing the Conquest 100 system, four concrete slab configurations were tested: multi-layer rebar with defects, single- and double-layer rebar setups, varied rebar spacing, and pre-corroded rebars (0–30% mass loss). GPR B-scans collected over 3–60 days demonstrated that detection accuracy varied significantly with curing time, structural complexity, and moisture levels. A custom-developed Python script surpassed EKKO_Project software in rebar localization, achieving lower position errors (0.4–0.7 inches compared to 0.5–1.25 inches). Notably, the amplitude of GPR signals unexpectedly increased with corrosion …

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Heat Pumps And Sustainable Building Operations: An Analysis Of Energy Efficiency, Emissions, And Life Cycle Costs, Mahdiyeh Zafaranchi Jun 2025

Heat Pumps And Sustainable Building Operations: An Analysis Of Energy Efficiency, Emissions, And Life Cycle Costs, Mahdiyeh Zafaranchi

Theses and Dissertations

Heating, ventilation, and air conditioning (HVAC) systems are a major contributor to energy demand. Heat pump technologies, particularly Ground Source Heat Pumps (GSHPs) and Air Source Heat Pumps (ASHPs), have emerged as key solutions to reduce energy use worldwide. However, their adoption is challenged by economic, operational, and environmental trade-offs. This dissertation develops a comprehensive framework for evaluating the energy efficiency, lifecycle emissions, and cost-effectiveness of GSHP and ASHP systems in sustainable building operations. Through advanced energy modeling, lifecycle assessments (LCA), and lifecycle cost (LCC) analyses, this research provides data-driven insights to optimize heat pump system selection. This study is …

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Couples And Pornography: A Dyadic Latent Profile Analysis Of Romantic Partners And Pornography Use, Michelle E. Haddock Edwards Jun 2025

Couples And Pornography: A Dyadic Latent Profile Analysis Of Romantic Partners And Pornography Use, Michelle E. Haddock Edwards

Theses and Dissertations

Research on the outcomes of pornography use for romantic couples has been extensive yet inconclusive. Studies have examined pornography use in a wide variety of contexts, leading to a wide variety of outcomes and well-being. The current study uses latent profile analysis to account for many contextual factors at once, dyadic data to examine the perspective of both partners simultaneously, and a range of individual and relational well-being outcomes to understand how different relational pornography use patterns lead to well-being. Results provided evidence for six unique profiles of couples based on pornography use patterns (personal use frequency, perceived partner use …

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Incorporating Propensity Score Weighting And Nonresposne Adjustments Into Complex Survey Data With Survival Outcomes, Xinrui Shi Jun 2025

Incorporating Propensity Score Weighting And Nonresposne Adjustments Into Complex Survey Data With Survival Outcomes, Xinrui Shi

Theses and Dissertations

Propensity score weighting (PSW) plays a key role in minimizing confounding in observational research, especially when estimating treatment effects for time-to-event outcomes. However, its integration into survey data with complex design – particularly data with multiple stage sampling and censoring – remains underexplored. One significant challenge in such settings is the presence of nonresponse, which can introduce additional bias and complicate the use of standard weight adjustments. Moreover, there has been limited study on how PS weights can be effectively combined with nonresponse weighting adjustments in complex survey data that include survival outcomes. This dissertation aims to extend current methodologies …

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The Development Of The Disclosed Reasons Of Partners' Premature Discontinuation In Couple Therapy Questionnaire (Dropped-Ct), Luca Codeca' Jun 2025

The Development Of The Disclosed Reasons Of Partners' Premature Discontinuation In Couple Therapy Questionnaire (Dropped-Ct), Luca Codeca'

Theses and Dissertations

Premature discontinuation from couple therapy presents a substantial challenge for clients, therapists, and society. Inconsistent data on the frequency and reasons for premature discontinuation may be attributed to a lack of methodological rigor in assessing the phenomenon. This study addresses this gap by developing the Disclosed Reasons Of PrEmature Discontinuation in Couple Therapy Questionnaire (DROPPED-CT), a comprehensive instrument designed to assess the reasons why couples prematurely discontinue therapy. Utilizing a mixed-method approach, the DROPPED-CT was developed through the integration of qualitative and quantitative data. The questionnaire demonstrates strong potential for enhancing the consistency of construct operationalization and improving the comparability …

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University Counseling Center Therapists' Perspectives Of Counseling About Nutrition, Ana Lucia Pacheco Jun 2025

University Counseling Center Therapists' Perspectives Of Counseling About Nutrition, Ana Lucia Pacheco

Theses and Dissertations

This study examined university counseling center therapists' perspectives on discussing nutrition in therapy. Despite the established link between nutrition and mental health, minimal research has explored how therapists approach these discussions. This study used interpretative phenomenological analysis (IPA) to analyze semi-structured interviews with 10 university counseling center therapists from the Mountain West region. Four overarching themes emerged: a deficit view of nutrition, perceived utility, ethical practice, and holistic care. Therapists unanimously recognized the connection between nutrition and mental health and primarily discussed nutrition with clients presenting with eating disorders or disordered eating, those who express interest, or as part of …

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Behavioral Skills Training: Comparing Parent Implementation To Registered Behavior Technician Implementation, Jessica Anderson Jun 2025

Behavioral Skills Training: Comparing Parent Implementation To Registered Behavior Technician Implementation, Jessica Anderson

Theses and Dissertations

Behavioral Skills Training (BST) is an evidence-based practice appropriate for practitioners, parents, clients, and other populations. It is frequently used in Applied Behavior Analysis (ABA) therapy to support and augment skill development. Parent training in ABA has been found to be beneficial, and often critical, in the progress of children with autism spectrum disorder (ASD). While BST is a popular method of parent training, it is unclear how effective this type of training is in comparison to the training given to a Registered Behavior Technician (RBT). This study took place in conjunction with an ABA clinic providing in home therapy. …

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The Influence Of Father Involvement On Early Childhood Outcome In China, Shuiyan Guo Jun 2025

The Influence Of Father Involvement On Early Childhood Outcome In China, Shuiyan Guo

Theses and Dissertations

Using a sample from China, this study examined the influence of father involvement on child outcome in early childhood in areas of internalizing problems, externalizing problems and prosocial behaviors. The participants were drawn from the larger PACIFIC project, a cross-cultural study of family processes in Asia. 479 families with a preschool or kindergarten child living in Beijing and Dalian, China were included in this study. Using multiple regression analysis, result indicated that father involvement was not significantly associated with child’s internalizing problems, externalizing problems, and prosocial behaviors. Moderation analysis was also conducted and found that the effect of father involvement …

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Therapist Experience As A Moderator Of Therapeutic Alliance Across The Course Of Couple Therapy, Julia K. Christensen Jun 2025

Therapist Experience As A Moderator Of Therapeutic Alliance Across The Course Of Couple Therapy, Julia K. Christensen

Theses and Dissertations

Therapeutic alliance is a key predictor of successful couple therapy outcomes. Little research has explored how therapist experience may predict its development. This study was designed to examine whether initial therapeutic alliance scores differ between couple clients of training clinics versus couple clients of community clinics, and whether the rate of change in alliance across sessions varies between these groups. Additionally, I controlled for initial relationship distress. Using dyadic therapy process data for at least one partner of 1,330 couples, a multilevel growth curve model with therapist experience as a moderator was fit to determine the difference in initial therapeutic …

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Reactivity To Environmental And Social Demands In Autistic And Neurotypical Children: More Alike Than Different?, Sarah-Ann Louder James Jun 2025

Reactivity To Environmental And Social Demands In Autistic And Neurotypical Children: More Alike Than Different?, Sarah-Ann Louder James

Theses and Dissertations

Research has increasingly recognized that empathy difficulties between autistic and neurotypical individuals are mutual. As empathy depends on shared understanding, identifying common ground between autistic and neurotypical children is important to foster greater empathy. This study examined reactivity patterns in autistic and neurotypical children to explore how similarities in reactivity might promote empathy across neurodiverse groups. Using a quantitative, survey-based design, parents of 56 children (19 autistic, 37 neurotypical; ages 5-11) completed a novel measure developed for this study, the Reactivity to Scenarios of Differing Intensity (RSDI), which measures children's reactivity to various social and environmental scenarios of differing intensity. …

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Latent Profiles Of Couples' Marital Power And Gender Ideologies: Associations With Physical Intimate Partner Violence, Rylie Speirs Jun 2025

Latent Profiles Of Couples' Marital Power And Gender Ideologies: Associations With Physical Intimate Partner Violence, Rylie Speirs

Theses and Dissertations

This study aims to identify couple typologies regarding gender ideologies and marital power, and investigate how couple typologies relate to sociodemographic characteristics as well as rates of physical intimate partner violence (IPV). Several theoretical approaches connect marital power and gender ideologies to IPV but emphasize different couple typologies. For example, family violence perspectives suggest gender ideology mismatch is a stressor that increases the likelihood of either spouse reporting low power or engaging in physical IPV. Feminist theories add that men may use IPV to maintain patriarchal power dynamics when women deviate from traditional gender norms, emphasizing the risk of IPV …

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Study Of Capital And Operation Costs For Reverse Osmosis Desalination Plants, Habiba Mahdy Mohamed Jun 2025

Study Of Capital And Operation Costs For Reverse Osmosis Desalination Plants, Habiba Mahdy Mohamed

Theses and Dissertations

Desalination is a progressively common solution to supply freshwater in numerous parts of the globe where this resource falls short. Among all desalination techniques, seawater reverse osmosis (SWRO) is the most globally prevalent technology. Evaluating a desalination technology's cost-effectiveness is essential to ensure a well-designed plant can be implemented successfully and within an acceptable budget. In the Egyptian context, where water scarcity heightens the urgency of effective resource allocation, economic indicators such as capital expenditure (CAPEX) and operational expenditure (OPEX) are pivotal in shaping policy and planning decisions. Adopting this integrated financial perspective ensures that desalination projects are not only …

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Unseen Burdens: Exploring Gender Disparities In Infertility Experience And Depressive Symptoms, Khiara Cardoza Brown Jun 2025

Unseen Burdens: Exploring Gender Disparities In Infertility Experience And Depressive Symptoms, Khiara Cardoza Brown

Theses and Dissertations

This study examines how experiences with infertility relate to mental health outcomes among newly married U.S. couples, emphasizing gender differences and the potential moderating role of gender attitudes. Using data from 3,137 individuals in a nationally representative sample, three Actor-Partner Interdependence Models were estimated: first assessing actor and partner effects of infertility on depressive symptoms and subsequently incorporating gender attitudes as moderators. Results indicated a significant actor effect for wives, where infertility was associated with higher levels of depressive symptoms, and this association was significantly stronger for wives than for husbands. No significant effects were found for husbands' infertility and …

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The Case For Visual Art In Overcoming The Double Empathy Problem, Katelyn Milea Rose Nilson Jun 2025

The Case For Visual Art In Overcoming The Double Empathy Problem, Katelyn Milea Rose Nilson

Theses and Dissertations

A person's cognitive environment--made up of their thoughts, experiences, and tendencies--can affect how they empathize with others. Those with significantly different cognitive environments, such as autistic and neurotypical individuals, may have a difficult time empathizing with one another. This study aimed to facilitate empathy between the two groups by aligning their cognitive environments through discussion about visual art. Five autistic neurotypical dyads completed three discussion sessions where they observed and journaled about a piece of art, discussed their thoughts with each other, and filled out a questionnaire about their experience. All participants also completed a post-study interview. Data from questionnaires, …

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Modeling The Mark 26 Guided Missile Launching System: Exploring Its Role In U.S. Naval Doctrine In The Late Cold War, Ryan Matthew Cabico Jun 2025

Modeling The Mark 26 Guided Missile Launching System: Exploring Its Role In U.S. Naval Doctrine In The Late Cold War, Ryan Matthew Cabico

Theses and Dissertations

The Mark 26 Guided Missile Launch System was an innovative and modular upgrade from previous systems for the United States Navy at a critical development point during the Cold War. Its incorporation into the Virginia-Class, especially the USS Arkansas, exemplified the rapidly evolving scope and demands of naval warfare in the modern era, and the requirements of individual vessels and component parts of the Navy to fulfill U.S. naval doctrine in this era. This same rapid evolution in technology and the global political landscape would ultimately seal the fate of the Mark 26 and USS Arkansas, with their designed innovations …

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Comparing Emotional Facial Expressions Produced During Personal Narrative Discourse By People With And Without Aphasia, Chloe K. Houghton Jun 2025

Comparing Emotional Facial Expressions Produced During Personal Narrative Discourse By People With And Without Aphasia, Chloe K. Houghton

Theses and Dissertations

This study investigated the differences in emotional facial expressivity between people with aphasia (PWA) and control participants during emotional discourse tasks. Participants consisted of 26 PWA and 26 control participants from Aphasia Talk Bank who retold a stroke or illness story and an important life event story, totaling 104 video files. Undergraduate research assistants were trained to code emotional facial expressions according to valence, intensity, and duration utilizing a modified Facial Expression Coding System (FACES; Kring & Sloan, 1991). Dependent variables included positive frequency, negative frequency, positive intensity, and negative intensity. Results from this study demonstrate that female participants used …

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A Multiple Case Study On Cisgender Women Experiences In Electrical And Computer Engineering And Computer Science Majors, Alena Marie Degeorge Jun 2025

A Multiple Case Study On Cisgender Women Experiences In Electrical And Computer Engineering And Computer Science Majors, Alena Marie Degeorge

Theses and Dissertations

Gender disparities are found in Science, Technology, Engineering, and Math (STEM) education because of gender norms and stereotypes that project the ideology that men are better at those subjects than women. Women who pursue a college education in STEM encounter barriers that influence them to switch to a non-STEM-related major making them part of the leaky pipeline. This case study examines the experiences that junior and senior cisgender women have while pursuing an electrical and computer engineering or computer science degree and how they overcome barriers they encounter to continue their educational pursuits in a Computer Science and Engineering (CSE) …

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Understanding The Perceptions Of Campus Racial Climate Of Black Undergraduate Students At A Pwi, Solana Reyes Jun 2025

Understanding The Perceptions Of Campus Racial Climate Of Black Undergraduate Students At A Pwi, Solana Reyes

Theses and Dissertations

The study explores the perceptions of Black undergraduate students regarding the racial climate at a predominantly white institution (PWI). Utilizing quantitative methodologies, the research examines how Black students experience and interpret interactions, institutional policies, and campus culture as they navigate spaces often characterized by racial homogeneity. Key areas of focus include feelings of belonging, exposure to microaggressions, access to culturally relevant resources, and the role of peer and faculty support in shaping these experiences. Findings reveal a complex interplay of support and alienation, with participants reporting both affirming and discriminatory experiences. Many students highlighted the significance of student-led cultural organizations …

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From One Campus To Another: Transfer Student Journeys, Meocha Dozier-Pendleton Jun 2025

From One Campus To Another: Transfer Student Journeys, Meocha Dozier-Pendleton

Theses and Dissertations

Community college systems offer accessible and affordable postsecondary education, with nearly half of all undergraduates attending public institutions opting for community colleges, particularly low-income, minority, and first-generation students. Less than 35% of students will reach the goal of transferring to a four-year institution within six years even though 80% of community college students intend to (Jabbar et al, 2019). This thesis explores the experiences of transfer students as they transition from one institution to another, focusing on the challenges they face and the support systems they rely on during this process. Focusing on transfer students can provide insights into why …

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Investigating Solvent Effects On Crystallization Kinetics, Ibrahim Joel Jun 2025

Investigating Solvent Effects On Crystallization Kinetics, Ibrahim Joel

Theses and Dissertations

The use of crystallization for separation is not a recent phenomenon. However, the development of efficient crystallization processes is continually being challenged by the complexity and high cost of new drug substances, coupled with stringent regulatory requirements, which add to the uncertainty surrounding drug launches by pharmaceutical enterprises. Accurate characterization of crystallization kinetics is a key step in crystallizer design, which can be influenced by several factors, including process conditions, scale, and the measurement techniques used for tracking particle evolution. These factors often lead to inconsistencies between kinetic studies, hindering rapid implementation within industrial contexts. This thesis presents a case …

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Efficient Signal Synthesis For Data Augmentation Using Generative Ai, Yagna Veera Narayan Kaasaragadda Jun 2025

Efficient Signal Synthesis For Data Augmentation Using Generative Ai, Yagna Veera Narayan Kaasaragadda

Theses and Dissertations

Modern signal processing AI applications face increasing demands for diverse training data while operating under computational constraints. State-of-the-art generative models, though effective, often require prohibitive resources, limiting their deployment in real-time or embedded systems. This thesis proposes a computationally efficient framework for synthetic signal generation using a two-stage architecture that combines a Vector Quantized Variational Autoencoder (VQ-VAE) with either a decoder-only transformer or a discrete diffusion model. The VQ-VAE encodes high-dimensional signals into discrete latent tokens, significantly reducing model complexity while enabling symbolic sequence modeling. These discrete representations are then modeled using transformer-based autoregressive models or Score Entropy Discrete Diffusion …

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Advances In And Applications Of Capillary Scale Liquid Chromatography, Samuel William Foster Jun 2025

Advances In And Applications Of Capillary Scale Liquid Chromatography, Samuel William Foster

Theses and Dissertations

Analytical-scale high performance liquid chromatography (HPLC) is one of the most widely used analytical techniques in the world. Efforts have been made to reduce the mobile phase consumption of HPLC by reducing the inner diameter (I.D.) of the column. By using capillary-scale columns (< 0.5 mm I.D.), separations can be performed with orders of magnitude less solvent consumption. This work describes advances made to capillary scale instrumentation as well as applications enabled by these advances. A compact capillary-scale LC was used for the analysis of numerous pharmaceutical and illicit drug compounds for point of need analysis. A miniaturized mass spectrometer was coupled to this instrument for on-line reaction monitoring within a standard chemical fume hood. Kinetic profiles of commercially available capillary columns were developed in order to provide guidance to others during column selection. The implementation of a column oven improved the analysis of large biopharmaceuticals. Several critical quality attributes of monoclonal antibodies including fragmentation, charge variants, and glycosylation profiles were able to be determined on the capillary scale. These results will help to make capillary-scale liquid chromatography a more viable solution for chromatographic analysis.

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From Lists To Infinite Scroll: A Comparative Analysis Of Youtube’S Two Recommendation Algorithms, Selimhan Dagtas Jun 2025

From Lists To Infinite Scroll: A Comparative Analysis Of Youtube’S Two Recommendation Algorithms, Selimhan Dagtas

Theses and Dissertations

As social media platforms increasingly dominate information consumption, the role of recommendation algorithms in determining user experience has grown both in complexity and impact. This thesis investigates the behavioral patterns and algorithmic preferences embedded within YouTube’s recommendation systems, comparing long- form videos with the rapidly growing category of short-form content, YouTube Shorts. Through a combination of automated data collection, engagement metric analysis, emotional sentiment detection, and toxicity assessment, this study analyzes the evolution of content over successive recommendation depths. Using a controlled digital environment, the research explores how content recommendations change in response to user behavior, including varying watch times …

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Exploring Soft Polymeric Nanoparticles For Targeted Biomolecule Delivery In Plant Cells, Mohammad Rashid Jun 2025

Exploring Soft Polymeric Nanoparticles For Targeted Biomolecule Delivery In Plant Cells, Mohammad Rashid

Theses and Dissertations

Safe and efficient agricultural practices require innovative technologies. Nanotechnology offers promising solutions for advancing plant agriculture by enabling the targeted delivery of biomolecules such as agrochemicals and nucleic acids. This study focuses on developing a safe nanotechnological approach for delivering molecules of interest into plant cells. We investigated the ability of four types of polymeric nanoparticles such as Polyethylene glycol N, Nʹ-dibutylethylenediamine (PEG-DB), Polyethylene glycol 2-pyrrolidin-1-yl-ethyl-amine (PEG-PY), Polyethyleneimine (PEI), Arabinoxylan (AX)+, and Zein+ to form conjugates with plasmid DNA (pDNA). Our findings confirm that plant-derived cationic nanopolymers, AX+ and Zein+, effectively bind negatively charged pDNA (pGFPGUSPlus) carrying a GFP reporter …

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Constraining Nuclear Data Uncertainty Requirements For The 19F(A, N)22Na Reaction For Non-Proliferation Applications, Tyler R. M. Smith Jun 2025

Constraining Nuclear Data Uncertainty Requirements For The 19F(A, N)22Na Reaction For Non-Proliferation Applications, Tyler R. M. Smith

Theses and Dissertations

This thesis explores the requirements on nuclear data uncertainties needed for the use of the 19F(α, n)22Na reaction for nuclear non-proliferation applications. An overview of how neutrons are produced from alpha decays in a UF6 medium is discussed. Calculation demonstrate the role nuclear data uncertainties effect the neutron yield and energy spectra as a function of enrichment.

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Equiangularity From Compatible Orthobiangularity, Tyler J. Myers Jun 2025

Equiangularity From Compatible Orthobiangularity, Tyler J. Myers

Theses and Dissertations

An equiangular tight frame (ETF) is an equal norm sequence of vectors in a Hilbert space whose coherence achieves equality in the Welch bound. Such sequences necessarily have minimal coherence and thus are, in some sense, as "spread out" in space as possible. ETFs have a variety of applications, such as compressed sensing and waveform design. The main problem in the study of ETFs is determining the pairs (D, N) for which an ETF with N vectors in a D-dimensional space exists. Real ETFs are moreover equivalent to a special subset of a well-studied class of graphs known as strongly …

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Isotope Production Modeling In Sodium-Cooled Fast Reactors, Aaron W. Burkhardt Jun 2025

Isotope Production Modeling In Sodium-Cooled Fast Reactors, Aaron W. Burkhardt

Theses and Dissertations

The accurate prediction of isotopic compositions in Sodium-Cooled Fast Reactors (SFRs) is essential for nuclear forensic analyses and international nuclear treaty monitoring, particularly with the increased global deployment of Generation-IV reactors. This research developed and validated a detailed computational model tailored specifically to the Prototype Fast Breeder Reactor (PFBR), employing advanced Monte Carlo neutron transport methods, sophisticated burnup modeling, and variance reduction techniques. Validation against empirical data from the Experimental Breeder Reactor-II confirmed the model’s accuracy, producing a comprehensive database of isotopic compositions across 301 assembly locations and 580 isotopes through the reactor’s initial operation and equilibrium cycle. The model …

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