Digital Commons Network^™

Liminality And Space In The Iliad And The Heike Monogatari, Jade Simmons

Theses and Dissertations

Both the Iliad and the Heike monogatari have received scholarly attention throughout the years, though rarely in comparison with one another. A few scholars, such as Tyler Creer and Naoko Yamagata, have attempted to examine the two side by side, but very little work has been done beyond their respective analyses. This is unsurprising as a cursory glance at the two texts suggests that they are too separated by time and space to warrant closer examination. I argue, however, that there is great value in analyzing the two side by side. Indeed, a closer look at these texts reveals that …

Improving Electrochemical Measurements And Informing Future Reprocessing Of Advanced Nuclear Fuels, J. Marvin Torrie

Theses and Dissertations

This research promotes the application of molten salts through developing analytical tools in electroanalytical studies and in the data analysis of vapor pressure data. The electrochemical community lacks standardized, stable, and repeatable reference electrode designs which threaten the reliability of measured thermophysical properties and repeatability of published studies. This work confirms the application of a saturated reference electrode design for molten chlorides systems that outperforms traditional Ag+/Ag reference electrodes. In the field of thermal physical property measurements, vapor pressure data for chloride salts are diffused throughout the literature, uncertainty quantification is absent or limited, and all previous studies rely on …

A Masked-Perturbation Model For Destabilization Security Games In Feedback Systems, Gabriel Michael Perry

Theses and Dissertations

In this thesis, we present a mathematical formulation for increasing cyberphysical system security. This model allows a system administrator to use assumptions about exposed signals to derive defense strategies meant to mitigate the system's vulnerability to feedback perturbation attacks. We begin with a survey of game theory with the goal of building the concepts of resource and security games. We then introduce our model, which is a security game; targets in this game are exposed signals in the model map of the system, and resources are perturbed or introduced dynamical relationships between these signals. This formulation, called the masked-perturbation model, …

Improving Reclamation Seeding Success Through Seed Technologies, Surface Preparation, And Microbial Inoculants, Josh M. De Santiago Lazalde

Theses and Dissertations

Revegetation of reclaimed lands is often limited by poor seed placement, unfavorable surface conditions, and reduced biological activity, particularly on steep or physically degraded substrates where broadcast seeding is commonly used. Improving early seeding establishment under these conditions requires approaches that address both physical and biological barriers to seedling development. We evaluated the effectiveness of surface preparation, seed technologies, and microbial inoculants for improving plant establishment in field and greenhouse settings relevant to mineland reclamation. At the field scale (Chapter 1), we investigated the effects of chain harrowing and seed enhancement treatments on the establishment of grasses, forbs, and shrubs …

Answers “Go By Water”: Felt Knowledge As An Alternative Epistemology In Othello, Annalisa Gulbrandsen

Theses and Dissertations

William Shakespeare's Othello is fundamentally a play about epistemology--how does one know what he/she knows amidst the sea of words, evidence, and misdirection? Traditionally, the problem of knowledge in Othello has been treated as an intellectual problem of the mind. However, this thesis argues that the play purposefully draws attention to the limits of what the mind can know by way of the eye (what is seen) and ear (what is spoken or heard), instead offering an alternative epistemology that is felt through embodiment. When Desdemona's words no longer have the power to affect what Othello believes, Desdemona's answers to …

Studies On The Contribution Of Osh6 To The Functions Of Late Endosomes, William King

Theses and Dissertations

The late endosome (LE) is a hub organelle connecting endocytic, biosynthetic, exocytotic, and autophagic vesicle traffic pathways. Malfunctions of LEs are associated with multiple age dependent diseases such as Parkinson’s disease (PD). Despite this significance, how cells refurbish lipids and proteins to LEs to maintain their sustained activities are not clear. Previous studies in the model organism budding yeast show that up-regulation of a lipid transporter Osh6 (PERG6-OSH6) accumulates phosphatidylinositol-4-phosphate (PI4P) on the trans-Golgi network. It also promotes vacuole fusion and maintains the robustness of vacuoles in aged cells. Since LEs are the organelle between the TGN and vacuoles in …

Model Unification: A Systematic Approach For The Cluster Expansion, Kolten Barfuss

Theses and Dissertations

A systematic approach for model unification of cluster expansion models is developed and demonstrated. The method builds on previous work with the Manifold Boundary Approximation Method (MBAM) to identify supremal models. The work is motivated by the exercise of unifying cluster expansion models – characterized by Π matrices – for two binary alloys that share one atomic species to form a model for the ternary alloy. The result is the Supremal Π Algorithm, a systematic unification algorithm that relies on an MBAM-informed understanding of models and on the singular value decomposition. The algorithm yields ΠΛ, a Π matrix for the …

Impacts Of Arbuscular Mycorrhizal Fungi And Novel Soil Amendments On Perennial Grass Establishment In Mineland Soils, Melissa M. Burrell

Theses and Dissertations

Establishing perennial vegetation on mine waste materials is one of the primary challenges in mine land reclamation. Waste rock and mine tailing substrates typically lack the physical structure, nutrient availability, and biological communities necessary to support plant establishment and long-term ecosystem recovery. As a result, revegetation efforts often experience poor seeding success and limited plant persistence despite intensive management efforts. These studies investigated two complementary strategies to improve perennial grass establishment in degraded mine substrates: restoring mycorrhizal associations and enhancing soil function through soil amendments. The first study examined the role of arbuscular mycorrhizal fungi (AMF) in facilitating plant establishment …

Metonymy In Sound: A Neurolinguistic Study Of Al-Mullalah Soundscape Using Fnirs, Rand Naser Muflih

Theses and Dissertations

This thesis offers an interdisciplinary exploration of the semantic and neurolinguistic development of Al-Mullalah, a traditional Palestinian "coded" song type. By combining metonymy, soundscape analysis, and functional neuroimaging, the study traces the evolution of Al-Mullalah from a localized, covert means of communication tied to historical struggle to a globally recognized auditory symbol of collective resilience. The research uses a multi-method approach. First, soundscape analysis demonstrates how Al-Mullalah functions within Palestinian aural counterpublics, strengthening communal memory through various uses. Second, a qualitative analysis of semantics and themes examines how the text's metonymic structures change over time. Lastly, a Functional Near-Infrared Spectroscopy …

Tracing Microplastics From Polymer-Coated Urea: Urban To Agricultural Pathways And Environmental Fate, Caden Joseph Seely

Theses and Dissertations

Polymer-coated urea (PCU) is widely used as a slow-release nitrogen (N) fertilizer because it improves N use efficiency and reduces losses through leaching, denitrification, and volatilization. However, the polymer coating raises concerns about potential microplastic (MP) transport to surface waters following fertilizer application. This thesis evaluates the off-site transport of MPs and associated nutrient and sediment losses from PCU in both urban landscape and agricultural systems. In the urban landscape study, treatments included sod, mulched beds, and water-efficient ground cover receiving uncoated urea, PCU, or liquid slow-release N at 225 kg N ha⁻¹ (with reduced rates for beds and ground …

Optimizing Seedling Emergence In Sagebrush-Steppe Restoration: The Role Of Sowing Depth, Seed Coatings, And Microsite Amendments, John Thomas Stromberg

Theses and Dissertations

Seedling survival of fall-sown seeds over the winter and subsequent emergence in spring is a major demographic bottleneck limiting recruitment in dryland restoration. Deeper sowing can place seeds in a more favorable soil environment with more stable moisture and moderated temperatures, but emergence from these depths is often constrained by the greater distance seedlings must grow to reach the surface and by mechanical resistance in the upper soil layer. In the first chapter of this thesis, we evaluated the use of a slow-release gibberellic acid (GA₃) polymer seed coating to aid in seedling emergence from deeper sowing depths. We compared …

Toward Human-Like Robot Behavior In Co-Manipulation: Learning From Human Dyad Performance, Adam Kenneth Jackson

Theses and Dissertations

Co-manipulation requires two or more agents to coordinate through a shared object while exchanging information through motion and force. Although this capability is routine for humans, robotic systems still struggle to participate in such interaction naturally and effectively. This thesis addresses that gap by studying human co-manipulation behavior, developing methods to quantify performance, collecting a leader-follower dataset that isolates haptic communication, and training data-driven controllers from human demonstrations. First, cumulative and real-time metrics were developed to quantify human dyad performance. In particular, the behavioral modes "quickly" and "smoothly" were formulated as measurable performance objectives using completion time and squared jerk. …

Biophysical Insights Into A Cryptic, Hydrophobic Binding Site On Pcna, Alexis Dispensa

Theses and Dissertations

Proteins are dynamic molecules whose functional landscapes extend beyond static structural representations. Transient cryptic pockets (buried cavities that emerge through protein motion) represent underexplored targets for allosteric regulation and drug discovery. General anesthetics are small, lipophilic, weakly polar molecules that are well suited to partition into such hydrophobic sites. In this work, environment-sensitive fluorescence, photoaffinity labeling, mass spectrometry, mutational analysis, and microsecond molecular dynamics simulations were integrated to discover and characterize a cryptic, highly apolar binding site within the hydrophobic core of human proliferating cell nuclear antigen (PCNA), a central scaffold in DNA replication and repair. Using the solvatochromic fluorescent …

Family Processes As A Protective Factor Between Adverse Childhood Experiences And Adolescent Delinquency, Tessa Johnson

Theses and Dissertations

This study explores whether family processes (i.e., parental attachment and parental discipline/monitoring) serve as protective factors between the relationship of adverse childhood experiences (ACEs) and adolescent delinquency. Prior research has established an association between ACEs and many negative life outcomes, including delinquent behavior, while strong parental attachment and parental discipline/monitoring are linked to lower rates of delinquency. However, the interplay of these three factors has been understudied. Drawing on data from the 2024 Florida Youth Substance Abuse Survey (FYSAS) (N=22,016), this study examines the relationship between ACEs, family processes, and delinquency using negative binomial regression models. Results indicate that parental …

Hybrid Bermudagrass Dormancy Management In A Cool-Season Climate, Clarissa H. Peterson

Theses and Dissertations

Hybrid bermudagrass (Cynodon dactylon [L.] Pers. × C. transvaalensis Burtt Davy) (HBG) is a water efficient warm-season turfgrass increasingly adopted in cool-season and semi-arid regions due to climate change and the demand for reduced irrigation inputs. However, prolonged winter dormancy limits its visual quality (verdure) and seasonal performance. This thesis evaluated multiple management strategies to modify dormancy dynamics and improve off-season turf quality in a cool-season environment. Field experiments assessed the effects of growth covers, fertilizers, colorants, surfactants, organic acids, and overseeding with cool-season species on HBG dormancy over two seasons. Dormancy responses were quantified using normalized difference vegetation index …

Advancing Cyclic Ion Mobility Mass Spectrometry For Structural Characterization, Isomer Discrimination And Gas-Phase Ion Chemistry, Sudam Shivaji Mane

Theses and Dissertations

This dissertation focuses on the development and application of high-resolution ion mobility-mass spectrometry (IMS-MS) methodologies for gas-phase separation and structural characterization of small molecules, with particular emphasis on epimers, positional isomers, and protomers. In addition to structural separations, this work investigates fundamental aspects of gas-phase ion chemistry using IMS-MS in combination with collision-induced ion activation and dissociation techniques. Advanced separations were performed using cyclic traveling-wave ion mobility spectrometry (cyclic TWIMS), implemented in a commercial cyclic ion mobility-mass spectrometry (cIMS) platform, to systematically evaluate both the capabilities and limitations of high-resolution IMS in resolving subtle structural differences. Initial studies demonstrated that, …

Redox Reprogramming In Neurogenesis: Candidate Developmental Switches And Targets Of Oxidative Toxicity In The Redox Proteome, Ryan Jacob Summerhays

Theses and Dissertations

Neurogenic differentiation requires coordinated redox regulation, yet how reversible cysteine oxidation is remodeled at proteome scale during this process remains poorly defined. Here, we asked whether differentiation is associated with selective, site-specific changes in reversible cysteine oxidation and whether oxidative stress reveals developmentally conditioned vulnerabilities within this redox landscape. To address this, we applied a discovery-oriented, proteome-scale redox profiling strategy that quantifies condition-dependent changes in reversible cysteine oxidation using CysPAT labeling, phosphopeptide enrichment, and multiplexed TMT mass spectrometry. Neurogenic differentiation was characterized by reproducible, bidirectional, and highly site-specific remodeling of reversible cysteine oxidation at discrete regulatory nodes, as well as …

Practical, Scalable, And Cost-Effective Nanolc-Ms Workflow For Single-Cell Proteomics, Siqi Huang

Theses and Dissertations

Single-cell proteomics provides a novel research strategy for decoding cellular heterogeneity, revealing the molecular mechanisms of rare cell subpopulations, and studying the dynamic responses of cells to external stimuli. However, compared to transcriptomics, single-cell proteomics faces even more challenging technical challenges: extremely low protein amount in single cells, wide dynamic range, significant adsorptive losses during sample preparation, and the complex matrix and trace sample injection demanding extremely high stability and sensitivity from the separation and detection systems. Mass spectrometry-based bottom-up proteomics has become an important tool for analyzing complex biological systems, and nano-flow liquid chromatography-mass spectrometry (nanoLC-MS) exhibits unique advantages …

Differentials As Models: Constructing A Differentials-Within-Limits Framework For First-Year Calculus And Examining Students' Understanding Of Limits, Differentials, And Derivatives Within It, Alexander A. Swindler

Theses and Dissertations

Work in first-year calculus has clearly shown the power that treating differentials (such as dx) as tiny quantities affords for first-year calculus learning, yet a traditional limits-based approach leaves no room for them. While some researchers have loosely described informal differentials and limits within the same paradigm, their actual conceptual definitions and relationships have not been explicitly constructed. Continued progress in this area could benefit from theoretical consideration of (a) providing clearer intuitive definitions for differentials inside a limits-based approach to calculus, and (b) defining more exactly the relationships between differentials and limits. In this study, I propose a theoretical …

Transcriptomic Analysis Of Xeroderma Pigmentosum Group C Skin Samples, Austen N. Gleave

Theses and Dissertations

Xeroderma Pigmentosum is a rare genetic disorder caused by defective DNA damage repair enzymes. This condition results in an increased risk of developing skin cancer and other symptoms in those affected. In this thesis, we examined the effects of Xeroderma Pigmentosum on gene expression in patient skin biopsy samples. To accomplish this, we utilized statistical analysis of spatial transcriptomic and single-cell RNA sequencing techniques to discover differences between patient and heterozygous carrier skin samples. We found that the skin samples from Xeroderma Pigmentosum patients showed elevated levels of inflammation, immune activation, and cellular stress, while the carrier skin samples leaned …

The Role Of Emerin In Myogenic Differentiation, Nicholas Marano

Theses and Dissertations

The nucleus harbors genetic material encapsulated by the nuclear envelope which is composed of an inner and outer nuclear membrane. The establishment and organization of chromatin at the INM is essential for cell fate during the differentiation program. Integral INM proteins are responsible for chromatin organization at the nuclear envelope. Emerin is a highly conserved type II integral INM protein with roles in chromatin organization, cell signaling, and nuclear structure. Mutations in the emerin gene cause Emery Dreifuss Muscular Dystrophy 1 (EDMD1). Emerin is ubiquitously expressed, but loss of emerin function affects specifically skeletal muscle and cardiac tissue. The precise …

Bridging The Gap: A Mixed-Methods Study Exploring The Relationships Between Student-Teacher Demographic Mismatch And Students’ Perceptions Of Fairness, Inclusion, And Achievement, Nicholas Nahrwold

Theses and Dissertations

This study examines the relationships between student-teacher demographic mismatch and students’ perceptions of fairness, inclusion, and achievement. The purpose of this research was to determine how race, gender, and SES mismatch between students and teachers is related to their feelings of belonging and academic outcomes. A mixed-methods study was conducted involving a combination of survey data, student performance records, and student interviews. Results from the study indicated a relationship between student-teacher gender match and GPA, student-teacher racial match and GPA, and student-teacher racial match and attendance outcomes. Although not statistically significant, the data collected also highlighted trends between student-teacher SES …

An Interpretable Hybrid Deep And Reinforcement Learning Paradigm For Glioma Prognosis, Renuga Devi M Ms

Theses and Dissertations

Brain tumors are highly aggressive and lethal types of cancer, particularly gliomas. These cancerous growths show complicated pathophysiological behaviours and with poor prognosis despite therapeutic advances. Due to their biological differences and infiltrating growth, as well as overlapping radiological characteristics, they pose great difficulty in diagnosis, grading, and survival prediction. Artificial intelligence technology, which includes machine learning , deep learning, and reinforcement learning has developed into a new paradigm for the automation of brain tumor diagnostics and personalized treatment. The main goal of this study is to create an integrated AI-based framework that can perform brain tumor segmentation, grading and …

Development Of Deep Fused Neural Architecture For Ancient Tamil Palm-Leaf Manuscript Recognition, Hariharan P Mr

Theses and Dissertations

Digitizing Tamil palm-leaf manuscripts is important for education, communication, and the preservation of cultural heritage. The complex structure of the Tamil script, the wide range of handwriting styles, and the degradation seen in ancient Tamil palm-leaf manuscripts make these texts very difficult to read and understand. Digital Image Processing (DIP), document analysis techniques, and traditional Optical Character Recognition (OCR) are unable to handle noise, background interference, faded ink, and limited labelled data, motivating the need for robust, effective Deep Learning (DL)- based solutions.

As a prerequisite to understanding and designing effective recognition systems for ancient manuscripts, this thesis first examines …

Database-Driven Revelations In Epilepsy: Patient Reporting Accuracy And The Circadian Timing Of Seizures, Ithay Biton

Theses and Dissertations

For over thirty years, patients have been visiting the Arkansas Epilepsy Program for diagnosis and treatment for seizures and seizure-like episodes. As part of their clinical evaluation, patients often undergo ambulatory EEG (electroencephalogram) monitoring. This routine process produces valuable data for treating the patient. In this study, over 2000 ambulatory EEG reports from 1998 to 2016 were reviewed. A large database of seizures was created from the reports, with information on 407 patients, 1611 EEG-confirmed seizures, and 1726 patient-reported seizures (IRB Protocol #17-093). The database was used to address two important issues in epilepsy. The first topic of the study …

Tunable 3d-Printed Biomaterials For Perfused In Vitro Models Of The Blood-Brain Barrier, Louis Salvatore Paone

Theses and Dissertations

In vitro models have tremendous utility for improving our understanding of complex physiological and pathophysiological processes in a more controlled environment than animal models, in addition to incorporating human cells to overcome species-specific disparities. This dissertation describes innovations in biomaterial-based fabrication processes that advance in vitro models of the blood-brain barrier, providing the opportunity to evaluate the effects of cell-matrix interactions on barrier integrity, additives to reduce viscous drag of blood flow, and molecular mechanisms underlying the cellular response to amyloid beta in the context of Alzheimer’s disease. The core technology underlying this advance is a biomaterial compatible with digital …

Jackfruit Peel Valorization Through An Integrated Biorefinery Approach, Rohil Kumar K Mr

Theses and Dissertations

Jackfruit (Artocarpus heterophyllus) peel (JFP), an abundantly available lignocellulosic biomass, remains largely underutilized despite being rich in cellulose, hemicellulose, lignin, and pectin. In India, approximately 13,460 hectares are under jackfruit cultivation, with Panruti in Tamil Nadu as a major production zone. The discarded peel often contributes to environmental pollution and greenhouse gas emissions. The present study emphasizes sustainable valorization of JFP through an integrated biorefinery framework for generating value-added bioproducts.

Major biopolymers, cellulose, hemicellulose, lignin, and pectin were extracted and fractionated, followed by detailed physicochemical characterization using FTIR, NMR, XRD, SEM, TGA, DSC, GPC, and BET analyses. Pectin extraction with …

Gendered Harms In Armed Conflict: International Legal Responses To The Gendered Effects Of The War In Sudan, Naima Dams

Theses and Dissertations

This thesis interrogates how international law conceptualizes, prosecutes, and ultimately limits the understanding of sexual violence in contexts of war and displacement. Drawing on feminist legal theory, postcolonial critique, and ethnographic fieldwork with Sudanese women displaced in Egypt, it questions the dominant legal framing of conflict-related sexual violence (CRSV) as episodic, exceptional, and individualized. Instead, it reveals sexual violence as structural, continuous, and embedded in the everyday realities of racialized, gendered, and colonial harm.

Through ethnographical narratives, the study exposes how survivors' experiences often exceed the legibility frameworks of humanitarian and legal institutions, which prioritize spectacular, forensic evidence over slow, …

Development Of An Ensemble Biosensor For Fatty Acids And Enhancing The Antibiotic Properties Of Meropenem With Hydrophobic Ion Paring And Nsf National I-Corps Experience And Commercialization Roadmap For The Paper Based Ensemble Biosensor For Ibs, Krishna Paul

Theses and Dissertations

This thesis integrates three interconnected studies focused on advancing biomedical diagnostics and therapeutic formulation. Primary task was developing an ensemble biosensor for multiplex fatty acid detection using protein - fluorophore interactions. A fluorescence matrix of BSA and FABP with 1,8-ANS, 2-AC, and fluorescein differentiated eight fatty acids with 94.59% accuracy. Validation in H. pylori positive stool samples confirmed its sensitivity and specificity with potentiality as a non-invasive diagnostic platform for Gastrointestinal and chronic diseases. The second project explores Hydrophobic Ion Pairing (HIP) to enhance the lipophilicity and bioactivity of the β-lactam antibiotic meropenem. HIP complexes with hydrophobic counter-ions improved stability, …

Deciphering Feup–Feuq Signaling: Mechanistic Analysis Of A Newly Identified Regulatory Module In Agrobacterium Tumefaciens, Michelle Charae Brock

Theses and Dissertations

Two-component systems (TCS) are widespread signal transduction pathways that enable bacteria to sense and respond to environmental changes with precision. TCS are fundamentally important to prokaryotes because they provide a rapid and efficient means of converting environmental stimuli into coordinated cellular responses. Unlike eukaryotes, which rely on multilayered signaling cascades and compartmentalized organelles, bacteria must interpret and react to changing conditions directly at the cell envelope. TCS allow prokaryotes to detect shifts in nutrients, osmolarity, pH, redox status, host-derived antimicrobials or competing microbes. This forces an immediate adjustment in gene expression programs to promote survival. Agrobacterium tumefaciens, a model organism …