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Articles 15991 - 16020 of 19641
Full-Text Articles in Entire DC Network
Mechanisms Of Accumulation And Biological Consequences Of Polynuclear Platinum Compounds, Peyman Kabolizadeh
Mechanisms Of Accumulation And Biological Consequences Of Polynuclear Platinum Compounds, Peyman Kabolizadeh
Theses and Dissertations
The novel trinuclear complex, BBR3464 has undergone Phase II clinical trials and been shown to have greater cytotoxicity and cellular uptake than clinical anticancer platinum drugs such as cisplatin, oxaliplatin and carboplatin. The clinical efficacy of cisplatin, oxaliplatin and carboplatin is limited due to acquired resistance and dose limiting side effects. The three major pharmacological factors contributing to the intrinsic cytotoxicity of, and cellular resistance to, platinum drugs are (i) cellular uptake and efflux of platinum; (ii) the frequency and nature of Pt-DNA adducts; and (iii) deactivating metabolic reactions with sulfur-containing nucleophiles. Since decreased cellular uptake of platinum drugs is …
A Comparison Of The Pectoral Spines In Virginia Catfishes, Amanda Dawn Duvall
A Comparison Of The Pectoral Spines In Virginia Catfishes, Amanda Dawn Duvall
Theses and Dissertations
Catfish pectoral spines are an anti-predator defense mechanism. They can be bound or locked, making the fish harder to swallow, or used to produce distress calls by rubbing ridges on the dorsal process against a channel in the wall of the pectoral girdle. Growth of the pectoral spine and girdle were examined in relation to fish size within and across species that occur throughout central and eastern Virginia. These included blue catfish (Ictalurus furcatus), channel catfish (Ictalurus punctatus), white catfish (Ameiurus catus), brown bullheads (Ameiurus nebulosus), yellow bullheads (Ameiurus natalis), flathead catfish (Pylodictis olivaris), margined madtom (Noturus insignis), and tadpole …
The Influence Of Adenoviral Infection And The Group Via Calcium-Independent Phospholipase A2 On Hepatic Lipid Metabolism, William Palmer Wilkins Iii
The Influence Of Adenoviral Infection And The Group Via Calcium-Independent Phospholipase A2 On Hepatic Lipid Metabolism, William Palmer Wilkins Iii
Theses and Dissertations
Sterol regulatory element-binding proteins (SREBP) are transcription factors that regulate genes involved in lipid metabolism especially in the liver. Therefore, hepatic SREBP is significant regulator of systemic lipid metabolism. Evidence demonstrates that insulin and dietary unsaturated fatty acid (UFA) regulate SREBP1 expression and subsequent SREBP1-mediated gene transcription, events that in many instances result in modulation of systemic fatty acid and triglyceride (TG) homeostasis. A series of investigations was designed to uncover novel regulators of SREBP1. Dietary and exogenous addition of UFA has been shown to regulate SREBP function yet, an endogenous source of UFA capable of modulating SREBP remains elusive. …
Interleukin-10 Suppresses Mast Cell Ige Receptor Expression And Signaling In Vitro And In Vivo, Sarah B. Kennedy
Interleukin-10 Suppresses Mast Cell Ige Receptor Expression And Signaling In Vitro And In Vivo, Sarah B. Kennedy
Theses and Dissertations
Background: Mast cells are known for their role in allergy, asthma, and systemic anaphylaxis, and have been shown to play a role in inflammatory disease. Interleukin-10 can regulate inflammatory responses both in vitro and in vivo, and may be a natural regulator of mast cell activation.Objective: To examine Interleukin-10 mediated regulation of FcεRI expression and related downstream signaling molecules, and to determine how this affects mast cell function in vitro and in vivo.Methods: Mast cell FcεRI expression was evaluated with and without IL-10 treatment in human lung and skin mast cells, and on peritoneal mast cells from mice overexpressing IL-10 …
Seeing It Straight, Heather Harvey
Seeing It Straight, Heather Harvey
Theses and Dissertations
This Master of Fine Arts thesis is divided into four main sections:FAITH and DISBELIEF: In which I reckon with the implications of faith versus rationality as a secular nontheistic artist. IDEAS: The central locus of my work is a place of indeterminacy between what is known/familiar and what is just one step outside of that. This has nothing to do with mysticism, science fiction, or anything else unmoored from established fact. Section also touches on the particular vantage of a female artist with working class roots.THE WORK: Selection of work made during graduate school, and the the guiding thoughts behind …
Concurrent Whitening And Orthodontic Treatment, Jason Thomas Gladwell
Concurrent Whitening And Orthodontic Treatment, Jason Thomas Gladwell
Theses and Dissertations
The aim was to evaluate whether a whitening system, when used during the final stages of orthodontics, would yield results comparable to whitening alone. Patients were assigned to either the control (n=20) or experimental (n=26) groups. At T1, patients were given a ten day supply of Trèswhite⢠by Opalescence®, instructions on use, and initial shade determination was made and photographs were taken. At T2 and T3, shade determination was accomplished and updated photographs were taken. Whitening of the teeth occurred in both groups on average, but significantly more whitening was experienced in the experimental group (p < 0.004). An average of 87% of teeth whitened during orthodontic treatment compared to 97% of control teeth (p < 0.01) were judged to be uniform in appearance. In conclusion, the data do not contraindicate the concurrent accomplishment of teeth whitening during orthodontic treatment.
Data Fusion Of Complementary Information From Parietal And Occipital Event Related Potentials For Early Diagnosis Of Alzheimer's Disease, Nicholas Stepenosky
Data Fusion Of Complementary Information From Parietal And Occipital Event Related Potentials For Early Diagnosis Of Alzheimer's Disease, Nicholas Stepenosky
Theses and Dissertations
The number of the elderly population affected by Alzheimer's disease is rapidly rising. The need to find an accurate, inexpensive, and non-intrusive procedure that can be made available to community healthcare providers for the early diagnosis of Alzheimer's disease is becoming an increasingly urgent public health concern. Several recent studies have looked at analyzing electroencephalogram signals through the use of many signal processing techniques. While their methods show great promise, the final outcome of these studies has been largely inconclusive. The inherent difficulty of the problem may be the cause of this outcome, but most likely it is due to …
Assessing Perceived Marriage Education Needs And Interests Of Latino Individuals In Utah County, Utah, Iliana Snyder
Assessing Perceived Marriage Education Needs And Interests Of Latino Individuals In Utah County, Utah, Iliana Snyder
Theses and Dissertations
This study utilized focus groups to assess the perceived needs and interests for marriage education among single and married Latino individuals residing in Utah County, Utah as well as the identification of common themes and differences for this population. Male and female groups at various points in the marital developmental life stage were studied including high school students (15-18 years of age), single never married young adults (19-30 years of age), committed (engaged or cohabiting) adults, married persons recently transitioning to parenting, and married people with children. The sample consisted of 10 groups, 5 female and 5 male. In addition, …
Life Stories Of Nikkeijin Seeking Better Opportunities: The Motivation Of Brazilian Immigrants In Japan, Marisa Utida Bellini
Life Stories Of Nikkeijin Seeking Better Opportunities: The Motivation Of Brazilian Immigrants In Japan, Marisa Utida Bellini
Theses and Dissertations
The immigration of Brazilian-Japanese to Japan has started as recently as the early 1980s as a result of an economic downturn in Brazil and labor shortages in Japan. In a recent study published by the Ministry of Justice in Japan, there are about 250,000 Brazilians currently working throughout Japan. Even though most of the Brazilians are second or third generation of Japanese descent, they are not fluent in Japanese, thus resulting in many cultural problems and misunderstandings. Some research has examined about the immigration of Brazilians (nikkeijin) to Japan, but none has investigated their acquisition of Japanese as a second …
Screencrayons: Using Screen Captures For Annotation And Research, Trent Alan Taufer
Screencrayons: Using Screen Captures For Annotation And Research, Trent Alan Taufer
Theses and Dissertations
In a world full of digital information we should be able to easily collect, organize, annotate, and leverage information from many different sources. This should be easy to do and not interrupt our normal workflow. A system to support information collection and organization should be user-friendly and as unobtrusive as possible, while still allowing for flexible and intelligent annotation. It should also be able to leverage the inherent information content of a collection of annotated information. We present a system that will demonstrate how these ideas can come together to make information collection easier and more productive. The system facilitates …
Multiscale Structure-Function Relations Of A Tendon, Lakiesha Nicole Williams
Multiscale Structure-Function Relations Of A Tendon, Lakiesha Nicole Williams
Theses and Dissertations
In 1998, the United States National Committee on Biomechanics (USNCB) established an evolving discipline called Functional Tissue Engineering (FTE). In establishing this discipline, the goals of the USNCB were to advance FTE by increasing awareness among tissue engineers about the importance of restoring function when engineering tissue constructs. Another goal was to encourage tissue engineers to incorporate these functional criteria in the design, manufacturing and optimization of tissue engineered constructs. Based on this motivation, an investigation of the structure and mechanical properties of the rabbit patellar tendon will be executed, with the ultimate goal of creating a multiscale soft tissue …
Single-Step Treatment Of 2,4-Dinitrotoluene Via Zero-Valent Metal Reduction And Chemical Oxidation, J. Mathew Thomas
Single-Step Treatment Of 2,4-Dinitrotoluene Via Zero-Valent Metal Reduction And Chemical Oxidation, J. Mathew Thomas
Theses and Dissertations
Many nitroaromatic compounds (NACs) are considered toxic and potential carcinogens. The purpose of this study was to develop an integrated reductive/oxidative process for treating NAC contaminated waters. The process consists of the combination of zero-valent manganese or iron and a hydroxyl radical based treatment technique. Corrosion promoters were added to the contaminated water to minimize passivation of the metallic species. Water contaminated with 2,4-dinitrotoluen (DNT) was treated with the integrated process using a recirculating batch reactor. It was demonstrated that addition of corrosion promoters to the contaminated water enhanced the rate of reaction of 2,4-DNT with zero-valent iron or manganese. …
Bacterial Source Tracking Of A Watershed Impacted By Cattle Pastures, Celina Phelps
Bacterial Source Tracking Of A Watershed Impacted By Cattle Pastures, Celina Phelps
Theses and Dissertations
Pathogenic microorganisms introduced by cattle may be transported to distant locations via watershed runoff. Escherichia coli, Enterococcus spp., and Streptococcus spp. are a few species present in runoff from land impacted by humans, cattle, and wildlife. Initial data reveals that E. coli concentrations in water are greater in areas impacted by cattle than by humans. And, wildlife contributes greater concentration fluctuations than either humans or cattle. When cattle are removed from a pasture, the bacterial concentrations rapidly decrease; however, slight variations in cattle herd size do not appear to significantly influence these counts. Amplified fragment length polymorphisms (AFLP) and repeated-sequence …
Clustering Multiple Contextually Related Heterogeneous Datasets, Mahmood Hossain
Clustering Multiple Contextually Related Heterogeneous Datasets, Mahmood Hossain
Theses and Dissertations
Traditional clustering is typically based on a single feature set. In some domains, several feature sets may be available to represent the same objects, but it may not be easy to compute a useful and effective integrated feature set. We hypothesize that clustering individual datasets and then combining them using a suitable ensemble algorithm will yield better quality clusters compared to the individual clustering or clustering based on an integrated feature set. We present two classes of algorithms to address the problem of combining the results of clustering obtained from multiple related datasets where the datasets represent identical or overlapping …
Effective Modeling Of Agricultural Practices Within Large-Scale Hydrologic And Water Quality Simulations, Zhijun Liu
Effective Modeling Of Agricultural Practices Within Large-Scale Hydrologic And Water Quality Simulations, Zhijun Liu
Theses and Dissertations
The previously developed watershed hydrological and water quality model for St. Louis Bay watershed by Kieffer (2002) was refined and calibrated. The aspects of model development refinement included development of fertilization-related nutrient input parameters, evaluation of nutrient input methods, development of plant uptake-related nutrient input parameters, non-cropland simulation using PQUAL module, and recalibration of hydrology in Jourdan River. The related information of typical cropland management practice based on consultation from Mississippi State University Extention Service personnel was integrated into the watershed model. In addition, the Mississippi Department of Environmental Quality (MDEQ) observed water quality data were analyzed to evaluate the …
Angiotensin Ii Mediated Regulation Of Signal Transduction In Metabolic Syndrome And Cancer, Ravindra Bharatrao Kolhe
Angiotensin Ii Mediated Regulation Of Signal Transduction In Metabolic Syndrome And Cancer, Ravindra Bharatrao Kolhe
Theses and Dissertations
Patients suffering from hypertension often develop non-Insulin dependent diabetes mellitus (NIDDM), a condition caused by Insulin resistance. Though these patients have normal Insulin receptor (IR) and high levels of Insulin in blood, they fail to have IR-mediated signaling essential for glucose uptake and availability. NIDDM usually begins as insulin resistance, a condition in which Insulin Receptor (IR)-mediated signaling that leads to glucose uptake and glucose availability to cells is inhibited even in the presence of high levels of Insulin in blood. Mechanisms for the development of this Insulin resistance in patients suffering from hypertension are unclear. Angiotensin II (Ang II) …
The Chemical And Mechanical Effects Of Binding Chitosan To Implant Quality Titanium, Holly Joy Martin
The Chemical And Mechanical Effects Of Binding Chitosan To Implant Quality Titanium, Holly Joy Martin
Theses and Dissertations
Biomedical implants are commonly made from commercially pure titanium and other metal alloys, which are chosen for their strength and density. To improve the stability and promote bone cell growth into the implant, efforts to bond coatings to metal have been extensively studied. Many coatings used are considered bioactive, which promote the adhesion and growth of the bone cells surrounding the implant [A.1]. Of these, the most commonly investigated coating is a ceramic called hydroxyapatite, which is brittle, leading to flaking and inadequate bone cell growth [A.2]. Alternate bioactive coatings are being examined, including chitosan, the deacetylated form of chitin. …
Effects Of Vasoactive Agents On The Mechanical Properties Of Aortic Heart Valve Leaflets, Rebecca Lynn Pounders Mathis
Effects Of Vasoactive Agents On The Mechanical Properties Of Aortic Heart Valve Leaflets, Rebecca Lynn Pounders Mathis
Theses and Dissertations
Heart valve disease is currently one of the leading forms of heart disease. Current literature has shown that endothelin I, angiotension II and 5-HT are vasoactive agents which cause concentration dependent contractions in aortic valve leaflet tissue. This study tested the mechanical properties of leaflets cut in the radial direction after they were exposed to the agents at varied concentrations or for 0.5, 6 or 24 hours. The elastic modulus, ultimate tensile strength and the yield strength were calculated. In the time trials the elastic modulus and the ultimate tensile strength both showed a significant increase at 24-hours. However, there …
Heat Transfer And Friction In Helically-Finned Tubes Using Artificial Neural Networks, Gregory J. Zdaniuk
Heat Transfer And Friction In Helically-Finned Tubes Using Artificial Neural Networks, Gregory J. Zdaniuk
Theses and Dissertations
The last few decades have seen a significant development of complex heat transfer enhancement geometries such as a helicallyinned tube. The arising problem is that as the fins become more complex, so does the prediction of their performance. In addition to discussing existing prediction tools, this dissertation demonstrates the successful use of artificial neural networks as a correlating method for experimentally- measured heat transfer and friction data of helicallyinned tubes.
Design Drawing In Instructional Design At Brigham Young University's Center For Instructional Design: A Case Study, S. Todd Stubbs
Design Drawing In Instructional Design At Brigham Young University's Center For Instructional Design: A Case Study, S. Todd Stubbs
Theses and Dissertations
The purpose of this study is to compare the use of design drawing in design fields such as architecture, engineering, and industrial design with its use in instructional design (ID). This study was conducted in three parts: first, a review of literature to understand the role and value design drawing plays in non-ID fields; second, a search for design drawing in the literature of ID; and third, observations of actual use of design drawing in ID in the field. For the first part, the literature of design studies was reviewed regarding design drawing. For the second part, the literature review …
Development Of A Health Management Information System For The Mountain Gorilla (Gorilla Beringei), Richard Brian Minnis
Development Of A Health Management Information System For The Mountain Gorilla (Gorilla Beringei), Richard Brian Minnis
Theses and Dissertations
The Mountain Gorillas of Central Africa are one of the most highly endangered species in the world, with only 740 individuals surviving. One of the greatest threats to this species is disease. Health of wildlife is continually garnering more attention in the public arena due to recent outbreaks of diseases such as West Nile and High Pathogenic Avian Influenza. However, no system currently exists to facilitate the management and analysis of wildlife health data. The research conducted herein was the development and testing of a health information monitoring system for the mountain gorillas entitled Internet-supported Management Program to Assist Conservation …
Effectiveness Of Postharvest Sanitation Treatments On Microbial Load Of Blueberries, Wei-Chun Chen
Effectiveness Of Postharvest Sanitation Treatments On Microbial Load Of Blueberries, Wei-Chun Chen
Theses and Dissertations
The purpose of this study was to determine the quality and microbial load of blueberries at different maturity stages, to develop the effective microbial recovery method and to compare sanitation postharvest treatments on microbial counts of blueberries. The soluble solids and the sugar to acid ratio increased, while pH and TA decreased with maturity. Ripe berries had lower yeast and mold counts (YMC) at other maturity stages, but there were no differences on aerobic plate counts (APC). The medium pH was lower for stomaching and blending than hand massaged samples. This leads to higher recovery of microorganisms by massaging. Sodium …
Establishment Of Blackberries And Detection And Management Of Raspberry Crown Borer, Edward Heard
Establishment Of Blackberries And Detection And Management Of Raspberry Crown Borer, Edward Heard
Theses and Dissertations
Evaluations of tactics for detection and management of raspberry crown borer, RCB, Pennisettia marginata (Harris) on blackberries were performed in Mississippi from January 2005 - July 2006. Randomized split plots with infested blackberries and certified nursery stock of two recommended cultivars, thorny ?Chickasaw? and thornless ?Apache? were planted. Pest management tactics targeting RCB included drenches: chemical insecticide bifenthrin, recently registered for RCB management; experimental pesticide E2Y45; and entomopathogenic nematodes Steinernema feltiae. Insect pheromones (E,Z)3-13-octadecadien-1-ol and (E,Z)3-13-octadecadien-1-yl-acetate were evaluated as RCB lures. Effects of fungicides captan, pyraclostrobin + boscalid, lime-sulfur and insecticide acetamiprid on viability and infectivity of entomopathogenic nematode species, …
Innovative Scintillating Optical Fibers For Detecting/Monitoring Gamma Radiation, Ashwini Jayaprakash
Innovative Scintillating Optical Fibers For Detecting/Monitoring Gamma Radiation, Ashwini Jayaprakash
Theses and Dissertations
A scintillating optical fiber sensor of this work consists of a scintillating optical fiber, connected to a photomultiplier tube (PMT) via a conventional silica optical fiber. When a gamma ray impinges on the scintillating optical fiber, photons are generated inside the fiber. The photons are trapped inside the fiber and guided through the PMT. The PMT output signal is acquired by a computer. Two types of scintillating optical fibers sensors were developed for gamma ray detection. The first one is a silica optical fiber doped with an inorganic scintillating agent. The second one is a liquid core waveguide optical fiber …
Field Emergence Of Horseweed [Conyza Canadensis (L.) Cronq.] And Control Utilizing Tillage And Herbicides, Thomas William Eubank
Field Emergence Of Horseweed [Conyza Canadensis (L.) Cronq.] And Control Utilizing Tillage And Herbicides, Thomas William Eubank
Theses and Dissertations
Horseweed has been documented in 70 countries and 40 different crops around the world and is listed as being a problem weed in no-till production systems. Horseweed has developed resistance to many herbicide modes of action including glycine. Field experiments were conducted from 2004 to 2006 in the Mississippi Delta to evaluate the field emergence of horseweed and most effective treatment programs for its control. Field emergence of horseweed was observed occurring primarily in the fall of the year, September through early November, when temperatures were between 15.6 to 23.4 C with later flushes occurring from late January through early …
Body Mass Index And Percent Body Fat As Determined By Bioelectrical Impedance Analysis In Children, 7-9 Years Of Age, Patrick Alan Grady
Body Mass Index And Percent Body Fat As Determined By Bioelectrical Impedance Analysis In Children, 7-9 Years Of Age, Patrick Alan Grady
Theses and Dissertations
The purpose of this study was to examine the prevalence of overweight and report mean Body Mass Index (BMI) and percent body fat (%BF) in Black and non-Black children, 7-9 years of age. The study involved 172 students divided as follows: 56 (32.6%) Black females, 45 (26.2%) Black males, 34 (19.7%) non-Black females, and 37 (21.5%) non-Black males. Percent body fat (%BF) was determined by bioelectrical impedance analysis (BIA). Body mass index was calculated as weight (kg)/height (m)². Black females had a statistically greater BMI (19.3 ± 4.8) and %BF (25.7 ± 10.6) than all other groups. Prevalence of at-riskor-overweight …
Functional Role Of Recombinant Cysteine Protease On Spodoptera Frugiperda Peritrophic Matrix, Srinidi Mohan
Functional Role Of Recombinant Cysteine Protease On Spodoptera Frugiperda Peritrophic Matrix, Srinidi Mohan
Theses and Dissertations
Fall armyworm larvae (FAW), which are serious pests in the southern United States, show retarded growth when they feed on insect-resistant maize inbreds Mp704 and Mp708. These maize genotypes are not only resistant to FAW, but to a number of other lepidopteran pests. In these genotypes, a unique, extracellular, 33-KDa cysteine protease (Mir1-CP) rapidly accumulates in the whorl in response to insect feeding. Initial morphological studies on larvae feeding on resistant maize plants over-expressing the cysteine protease showed severe damage in insect?s first line of defense, the peritrophic matrix (PM). But it is not known whether the cysteine protease has …
Sds-Page And Western Blotting Analyses Of Internalin A In Listeria Monocytogenes And Listeria Spp, Bang-Yuan Chen
Sds-Page And Western Blotting Analyses Of Internalin A In Listeria Monocytogenes And Listeria Spp, Bang-Yuan Chen
Theses and Dissertations
Attachment strength of Listeria spp. and their InlA expression was assessed. Listeria monocytogenes 19111 exhibited the strongest attachment strength with L. monocytogenes 19115, L. grayi, L. innocua, and L. monocytogenes 7644 being the weakest. InlA expression was not detected in silver stained SDS gels but was detected in Western blotting images. Internalin A was only detected in protein extracts of L. monocytogenes 19111 and 7644 with band intensities of 50.1 and 2.5 pixels, respectively. Greater InlA expression was correlated with higher attachment strength in L. monocytogenes 19111. Listeria monocytogenes 19115 did not express InlA but it had a stronger attachment …
Impact Of Foliar Fungicides On Yield And Net Returns In Soybeans, Benjamin L. Spinks
Impact Of Foliar Fungicides On Yield And Net Returns In Soybeans, Benjamin L. Spinks
Theses and Dissertations
Field studies were conducted in 2003, 2004, and 2005 in the Mississippi delta at 12 locations across common production practices to evaluate the impact of 12 single applications of fungicides at the R3 and R5 growth stage on soybean yield, seed quality, and net returns. Averaged across locations, azoxystrobin alone and mixed with other fungicides increased yields 161 to 343 kg/ha compared to the nontreated control. Fungicide applications made at R3-R4 were more efficacious and resulted in larger yield increases than applications made at R5-R6. Plots treated at the R3-R4 growth stage with 0.11kg ai/ha azoxystrobin alone or in combination …
Influence Of Food-Grade Ingredients On Offlavor Compounds In Catfish Fillets, Sovann Kin
Influence Of Food-Grade Ingredients On Offlavor Compounds In Catfish Fillets, Sovann Kin
Theses and Dissertations
The purpose of this study was to screen the effect of some food-grade ingredients on the off-odors caused by geosmin and 2-methylisoborneol (MIB) compounds in catfish fillets by sensory evaluation. The study revealed that geosmin and MIB odor intensity were reduced to different degrees when fillets were dipped in lime flavor (94% and 67%, respectively), 0.5% acetic acid (AA) (70% and 16%, respectively), hardwood liquid smoke (98% and 86%, respectively), or hickory liquid smoke (98% and 100% respectively) in cooked products. A 0.5% AA proved to be effective in decreasing odor intensity of geosmin (70%) in cooked products, whereas lime …