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Medication-Related Problems In Older Adults: A Focus On Underuse Of Warfarin And Warfarin-Antibiotic Interactions, Parinaz K. Ghaswalla Dec 2011

Medication-Related Problems In Older Adults: A Focus On Underuse Of Warfarin And Warfarin-Antibiotic Interactions, Parinaz K. Ghaswalla

Theses and Dissertations

The work presented in this dissertation focuses on two important medication-related problems in older adults, that is, untreated indication and drug-drug interactions, specifically with respect to a high-risk medication such as warfarin. Warfarin is a challenge to use in clinical practice due to its narrow therapeutic index, variability in dose-response and its interactions with numerous foods and drugs. This dissertation presents the research from two projects. In the first project the prevalence and predictors of warfarin use in nursing home (NH) residents with atrial fibrillation (AF), and use of secondary stroke prevention strategies was determined, in order to understand the …

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Assessing Parental Involvement In Type 1 Diabetes Management During Adolescence, Elizabeth M. Robinson Dec 2011

Assessing Parental Involvement In Type 1 Diabetes Management During Adolescence, Elizabeth M. Robinson

Theses and Dissertations

Type 1 diabetes is one of the most common pediatric chronic illnesses. Adolescents are at risk for poorer glycemic control; however, youth whose parents remain involved in diabetes care are in better control. The current study examined parental involvement (PI) using a multi-method, multi-source approach in a sample of 255 youth (Age M = 12.83). The Diabetes Family Responsibility Questionnaire, Parental Monitoring of Diabetes Care Scale, and 24-Hour Diabetes Interview assessed two types of PI, parental responsibility and parental monitoring. Global and specific assessment served to cross-corroborate indicators of PI related to HbA1c. Higher levels of monitoring related to lower …

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Characterization Of Two Genes For Resistance To Aflatoxin Accumulation In Maize (Zea Mays L.), John Erik Mylroie Dec 2011

Characterization Of Two Genes For Resistance To Aflatoxin Accumulation In Maize (Zea Mays L.), John Erik Mylroie

Theses and Dissertations

Maize (Zea mays L.) is one of the world’s largest food crops and thus any pathogens of maize are of great importance. Aspergillus flavus is one of these pathogens and it produces a carcinogenic metabolite called aflatoxin. Efforts to reduce infection by A. flavus and subsequent aflatoxin accumulation include the development of maize lines resistant to aflatoxin accumulation. However, resistant lines that have been developed contain agronomically unfavorable traits. Gene-based markers would allow for easier transfer of resistance from resistant inbred lines into maize lines with good agronomic traits. The focus of this research was the development of gene-based markers …

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Differences In Fatty Acid Content Of Homogenized And Non-Homogenized Milk From Holstein And Jersey Cows, Amanda Jean Frahm Dec 2011

Differences In Fatty Acid Content Of Homogenized And Non-Homogenized Milk From Holstein And Jersey Cows, Amanda Jean Frahm

Theses and Dissertations

The objective of this study was to investigate fatty acid concentrations of homogenized and non-homogenized milk from Jersey and Holstein cows. Twenty-two, lactating Holstein (n=11) and Jersey (n=11) cows were fed the same ration with Calan® gates twice daily. Jerseys were fed 25kg DM and Holsteins were fed 30 kg DM. Feed offered was adjusted daily according to previous day orts amount. Body weight and measurements, blood, and ruminal samples were collected weekly as were feed and orts samples. Ruminal fluid was collected from six Holstein and six Jersey cows weekly (n=42). Milk weights were collected daily and samples were …

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Evaluation Of Otter Trawls And Trotlines For Catching Pallid Sturgeon In The Freelowing Lower Mississippi River, Patrick Peterson Mirick Dec 2011

Evaluation Of Otter Trawls And Trotlines For Catching Pallid Sturgeon In The Freelowing Lower Mississippi River, Patrick Peterson Mirick

Theses and Dissertations

Stock assessment and behavioral studies are needed to identify habitat use and population dynamics of endangered pallid sturgeon Scahphirhynchus albus in the freelowing lower Mississippi River; however, effective sampling methods have not been evaluated. Trotlines and otter trawls were consequently fished year-round to determine the more effective gear and to determine effects of environmental variables on catch rates. Trotlines were more effective for catching large (> 600 mm FL) pallid sturgeon and neither gear was effective for catching small (100-600 mm FL) pallid sturgeon. Greater predicted probabilities of catching large pallid sturgeon with trotlines were in 9-19 °C water temperatures, …

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Exploring The 'Moment Of Knowing' And Double-Consciousness In Nella Larsen's Passing, Carina Lewis Dec 2011

Exploring The 'Moment Of Knowing' And Double-Consciousness In Nella Larsen's Passing, Carina Lewis

Theses and Dissertations

This essay explores early twentieth century African American literature to investigate issues related to identity formation. It uses W.E.B. Du Bois’s The Souls of Black Folk and Frantz Fanon’s Black Skin, White Masks to introduce and define the socio-psychological concept of the moment of knowing, an original component of this work. The concept is composed of two occurrences: alienation and self-alienation, which can be observed and examined in nonictional and fictional texts. Within the framework of multicultural theory, the moment of knowing along with double-consciousness are explored in a close reading of Nella Larsen’s 1929 novel Passing. In conclusion, the …

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In-Situ Catalytic Upgrading Of Pyrolysis Vapor, Vamshi Krishna Guda Dec 2011

In-Situ Catalytic Upgrading Of Pyrolysis Vapor, Vamshi Krishna Guda

Theses and Dissertations

The rising fuel prices, environmental concerns over the emission of greenhouse gases, and the limited availability of fossil fuels led to the current focus on developing alternative fuel sources that are sustainable and environmentally benign. Lignocellulosic biomass, due to its high carbon value, abundance and for being greenhouse gas neutral, is a promising alternative energy resource. Fast pyrolysis of lignocellulosic biomass produces high energy density liquid fuel, called bio-oil, which has the potential as transportation fuel. But, crude bio-oils are chemically complex liquids with high oxygen contents (40 % oxygen content), high viscosity, low pH, low thermal stability, and poor …

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Life History Studies Of Two Digenetic Trematodes, Bolbophorus Damnificus And An Unknown Clinostomoid Species, That Infect Channel Catfish Ictalurus Punctatus, Cynthia Michelle Doffitt Dec 2011

Life History Studies Of Two Digenetic Trematodes, Bolbophorus Damnificus And An Unknown Clinostomoid Species, That Infect Channel Catfish Ictalurus Punctatus, Cynthia Michelle Doffitt

Theses and Dissertations

The commercial production of channel catfish (Ictalurus punctatus) is major industry in Mississippi. Infections of channel catfish with the digenetic trematode Bolbophorus damnificus have often been associated with heavy economic losses in the industry. To efficiently control transmission of this trematode, the avian hosts need to be identified. In the first study, two American white pelicans, two double-crested cormorants, two great blue herons, and two great egrets were fed channel catfish infected with B. damnificus metacercariae. The presence of Bolbophorus damnificus ova in pelican feces at three days post infection (dpi) indicated the pelicans had patent infections. Mature B. damnificus …

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Human Predation Risk Effects On Adult, Male White-Tailed Deer Antipredator Behavior, Andrew Richard Little Dec 2011

Human Predation Risk Effects On Adult, Male White-Tailed Deer Antipredator Behavior, Andrew Richard Little

Theses and Dissertations

Recreational hunters play an important role in managing white-tailed deer (Odocoileus virginianus); however, the potential for deer to alter behaviors to avoid hunters has not been addressed within the risk-allocation hypothesis. I evaluated magnitude (i.e., hunter density) and temporal variation (i.e., time of day and initial and prolonged exposure) in human predation risk on movements, resource selection, and observation rates of 37 adult male deer in southern Oklahoma. Deer recognized human predation risk by increasing diel path complexity and use of security cover with greater hunter density. Moreover, deer reduced movement rates and tortuosity while seeking out areas with security …

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Ann-Based Fault Classification And Location On Mvdc Cables Of Shipboard Power Systems, Naveen Kumar Chanda Dec 2011

Ann-Based Fault Classification And Location On Mvdc Cables Of Shipboard Power Systems, Naveen Kumar Chanda

Theses and Dissertations

Uninterrupted power supply is an important requirement for electric ship since it has to confront frequent travel and hostilities. However, the occurrence of faults in the shipboard power systems interrupts the power service continuity and leads to the severe damage on the electrical equipments. Faults need to be quickly detected and isolated in order to restore the power supply and prevent the massive cascading outage effect on the electrical equipments. This thesis presents an Artificial Neural Network (ANN) based method for the fault classification and location in MVDC shipboard power systems using the transient information in the fault voltage and …

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Functional Characterization Of The Ocfc Gene And Optimization Of Medium Components And Culture Condition For Occidiofungin Production By Burkholderia Contaminans Strain Ms14, Kuan-Chih Chen Dec 2011

Functional Characterization Of The Ocfc Gene And Optimization Of Medium Components And Culture Condition For Occidiofungin Production By Burkholderia Contaminans Strain Ms14, Kuan-Chih Chen

Theses and Dissertations

he 56-kb ocfC gene cluster is required for occidiofungin production by Burkholderia contaminans strain MS14. However, the function of the ocfC gene remains unknown. Sequence analysis showed the putative protein encoded by ocfC shares significant identities to glycosyltransferase. Plate bioassays showed that occidiofungin production by the ocfC mutant (ocfC::nptII) was significantly reduced as compared with strain MS14. The occidiofungin produced by the ocfC mutant is xyloseree, which suggests the ocfC gene encodes a xylosyltransferase to add a xylose to the peptide backbone. Single variant optimization of culture condition and medium compositions was also performed in this study. The results indicated …

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Prey Specificity Of Thanasimus Dubius Between Latent And Intermediate Phases Of Southern Pine Beetle, Ryann Skiles Campbell Dec 2011

Prey Specificity Of Thanasimus Dubius Between Latent And Intermediate Phases Of Southern Pine Beetle, Ryann Skiles Campbell

Theses and Dissertations

This study investigates the pheromone preference of a bark beetle predator Thanasimus dubius between latent and intermediate phases of southern pine beetle. Two trap treatments were set up in each SPB phase. Standard Lindgren funnel traps were baited with either SPB lures or Ips lures. The number of T. dubius caught in each trap was recorded and data was analyzed using both the Mann Whitney U test and a two-way factorial ANOVA. Thanasimus dubius showed no variation in SPB pheromone preference but did show a slight increase in preference for Ips pheromones in intermediate phase areas. A protocol was developed …

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Study Of Excited Superdeformed Bands In 154dy And High-Spin Spectroscopy Of 171hf, Qurant Ul Ann Ijaz Dec 2011

Study Of Excited Superdeformed Bands In 154dy And High-Spin Spectroscopy Of 171hf, Qurant Ul Ann Ijaz

Theses and Dissertations

The first project in this dissertation involves the search for and the study of excited superdeformed (SD) rotational bands in 154Dy. The data was obtained from an experiment at the 88-inch cyclotron of the Lawrence Berkeley National Laboratory via the fusion evaporation reaction 122Sn(36S, 4n) and using the Gammasphere spectrometer array to probe the high-spin states in 154Dy. With the help of large Compton-suppressed spectrometers such as GAMMASPHERE in the USA and EUROBALL in Europe, superdeformed nuclei have been identified in several regions of the chart of nuclides including 151Dy, 153Dy, 154Dy and 155Dy. The 154Dy nucleus, located in the …

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Study Of Food Digestion And Morphology Of Subterranean Termites From Mississippi, Timothy Joseph Arquette Dec 2011

Study Of Food Digestion And Morphology Of Subterranean Termites From Mississippi, Timothy Joseph Arquette

Theses and Dissertations

The overall aim of this study was to provide new and updated information about subterranean termite morphology and digestive physiology. Scanning electron microscopy was used to obtain high resolution images of morphological features of the termite cuticle not discernable by light microscopy. In addition, digital scanning electron micrographs clearly show the appearance of wood particles recovered from the termite digestive tract at different stages of digestion. The ability of termites to obtain and conserve nitrogen in their diet was demonstrated by establishing whether the insect can digest chitin, as well as from determination of levels of soluble proteins and uric …

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Surface-Enhanced Raman Spectroscopy Of Thiobarbituric Acid (Tba) And Tba Reactive Compounds, Pravindya Rukshani Haputhanthri Dec 2011

Surface-Enhanced Raman Spectroscopy Of Thiobarbituric Acid (Tba) And Tba Reactive Compounds, Pravindya Rukshani Haputhanthri

Theses and Dissertations

Malondialdehyde (MDA) is the commonly accepted biomarker of lipid peroxidation. We reported the surface-enhanced Raman (SERS) detection of MDA using Thiobarbituric acid (TBA) as a molecular probe. The lowest concentration of HPLC purified TBA-MDA adduct that can be determined with reasonable signal to noise ratio is 0.45 nM. The specificity of the SERS technique has been demonstrated by comparing the SERS spectrum of TBA-MDA adduct with other TBA-aldehyde adducts. As a small organosulfur compound, TBA exhibits tremendous structural complexity. Discussed in this thesis is the drastic pH and concentration dependence of TBA SERS spectral features. To understand the origins of …

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Retained Woody Structure In 1-Year-Old Loblolly Pine Plantations In Mississippi, Louisiana, And Arkansas, Justin Neu Dec 2011

Retained Woody Structure In 1-Year-Old Loblolly Pine Plantations In Mississippi, Louisiana, And Arkansas, Justin Neu

Theses and Dissertations

I evaluated effects of 4 common site preparation techniques on residual structure while comparing 2 techniques commonly used to estimate CWD volume in Southeast loblolly pine (Pinus taeda) commercial pine plantations in 2 ecoprovinces. The strip plot method (SPM) estimated greater volume than the line intercept method (LIM; 9.7 m3/ha and 11.4 m3/ha respectively). The SPM had lesser volume estimate variability and appears more appropriate for the Southeast. Mechanical sites had the greatest densities of green trees and fewest snag retention and overall were least decayed. Chemical preparation combinations had lesser green tree densities but greater snag densities. Piled CWD …

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Peripheral And Placental Immunology In The Feline Immunodeficiency Virus (Fiv)-Infected Cat Model, Crystal Elizabeth Boudreaux Dec 2011

Peripheral And Placental Immunology In The Feline Immunodeficiency Virus (Fiv)-Infected Cat Model, Crystal Elizabeth Boudreaux

Theses and Dissertations

We are using the feline immunodeficiency virus (FIV)-infected cat to model HIV mother-to-child-transmission (MTCT). Vertical transmission of either virus may result not only in infected offspring, but also failed pregnancy.In HIV infections, maternal hematological and virological parameters predict MTCT.We hypothesized that such parameters would likewise be predictors of FIV vertical transfer. We inoculated ten cats with FIV-B-2542; 10 cats were uninoculated. Cats were allowed to breed naturally. Fetuses were delivered at approximately week 3 (early) gestation by cesarean section. Fetal and placental tissues were collected.Blood samples were collected from the day of inoculation through delivery. We quantified CD4:CD8 T cell …

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Activated Sludge As Renewable Fuels And Oleochemicals Feedstock, Emmanuel Durante Revellame Dec 2011

Activated Sludge As Renewable Fuels And Oleochemicals Feedstock, Emmanuel Durante Revellame

Theses and Dissertations

The utilization of activated sludge as feedstock for biofuel and oleochemical production was investigated. Initial studies included optimization of biodiesel production from this feedstock through in situ transesterification. Results of these studies indicated that activated sludge biodiesel is not economically viable. This was primarily due to relatively low yields and the high economics of feedstock dewatering. Strategies to increase biofuel yield from activated sludge were then evaluated. Bacterial species present in activated sludge are known to produce a wide variety of lipidic compounds as carbon and energy storage material and as components of their cellular structures. In addition to lipidic …

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An Economic Analysis Of Health, Savings, And Labor In Relation To Gender, Comfort Febisola Ricketts Dec 2011

An Economic Analysis Of Health, Savings, And Labor In Relation To Gender, Comfort Febisola Ricketts

Theses and Dissertations

This dissertation is divided into five chapters consisting of three short essays that concentrate on economic analysis of health, savings and labor. The first essay is aimed at investigating the influence of increased work hours on individuals’ health and how this may differ between males and females. It is expected that increased hours of work will have a negative impact on health but this impact may be stronger for females. In the second essay, the relationship between individuals’ health and savings behavior is analyzed. Healthy individuals are expected to be more productive, earn higher incomes, and have lower medical expenditures …

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A Genomic And Transcriptomic Analysis Of Wood Decay And Copper Tolerance In The Brown Rot Fungus Fibroporia Radiculosa, Juliet D. Tang Dec 2011

A Genomic And Transcriptomic Analysis Of Wood Decay And Copper Tolerance In The Brown Rot Fungus Fibroporia Radiculosa, Juliet D. Tang

Theses and Dissertations

Brown rot fungi are notoriously copper-tolerant, which makes them difficult to control with copper-based wood preservatives. Brown rot fungi are also unique because they have evolved a bilateral strategy for decay. Their initial attack involves the production of hydroxyl free radicals to increase wood porosity, followed by an enzymatic onslaught of glycoside hydrolases that free the sugars locked within cellulose and hemicellulose. Our molecular understanding of these biological processes, however, has been hampered by our limited knowledge of the underlying genetic mechanisms. To address this knowledge gap, high-throughput, short-read sequencing was used to conduct a comprehensive analysis of the genomics …

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The 3d Dynamics Of The Cosserat Rod As Applied To Continuum Robotics, Charles Rees Jones Dec 2011

The 3d Dynamics Of The Cosserat Rod As Applied To Continuum Robotics, Charles Rees Jones

Theses and Dissertations

In the effort to simulate the biologically inspired continuum robot’s dynamic capabilities, researchers have been faced with the daunting task of simulating—in real-time—the complete three dimensional dynamics of the the “beam-like” structure which includes the three “stiff” degrees-ofreedom transverse and dilational shear. Therefore, researchers have traditionally limited the difficulty of the problem with simplifying assumptions. This study, however, puts forward a solution which makes no simplifying assumptions and trades off only the real-time requirement of the desired solution. The solution is a Finite Difference Time Domain method employing an explicit single step method with cheap right hands sides. The cheap …

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Thermoregulation, Risk, And Den Stability Influence Grizzly Bear Den-Site Selection, Nathan Steven Libal Dec 2011

Thermoregulation, Risk, And Den Stability Influence Grizzly Bear Den-Site Selection, Nathan Steven Libal

Theses and Dissertations

Grizzly bear (Ursus arctos) den-site selection may be influenced by multiple factors at varying spatial extents. To test for hierarchical selection, I compared grizzly bear den sites (n = 21) to random locations in the Southern Lakes, Yukon at two scales: mesoscale (within 1 km of dens) and microscale (within 100 m of dens). I observed selection for den opening slope, pixel slope, soil content, and horizontal cover at the mesoscale. At the microscale, I observed selection for opening slope and horizontal cover. To further test the role of security and the sex hypothesis of sexual segregation, I compared adult …

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Variability Of Sediment Nutrients And Benthic Macro-Invertebrates In Recreational Fishing Ponds, Tyler James Stubbs Dec 2011

Variability Of Sediment Nutrients And Benthic Macro-Invertebrates In Recreational Fishing Ponds, Tyler James Stubbs

Theses and Dissertations

The overall objective of this study was to identify trends of sediment nutrients and benthic macro-invertebrates in recreational fishing ponds. The Ekman dredge and the Yabby pump, also were compared for benthic macro-invertebrate sampling effectiveness. Large ranges in the coefficient of variation for Pw (52 – 123.9), C:N (13.4 – 124), density (61.5 – 98.5), and diversity (67 – 142) indicated significant spatial variability within and among ponds. Invertebrate familial diversity was the only variable that did not show any significant temporal variation (H = 4.31, P = 0.230). Results from the gear comparison indicated no differences between the Ekman …

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Regulation Of Selective Delignification In The White-Rot Decay Fungus Phanerochaete Chrysosporium, Leslie Anne Parker Dec 2011

Regulation Of Selective Delignification In The White-Rot Decay Fungus Phanerochaete Chrysosporium, Leslie Anne Parker

Theses and Dissertations

To gain a better understanding of the mechanisms by which the white-rot decay fungus Phanerochaete chrysosporium regulates selective delignification versus simultaneous decay, differential gene expression of its two key enzymes were measured over the course of aspen and birch wood decay tests. The type of decay was determined by differential staining and scanning electron microscopy. Real-time qPCR assessed gene expression of four lignin peroxidase genes and two manganese peroxidase genes at each stage of decay. Differential expression was significant in the mnp2 gene between aspen and birch decay tests during incipient decay; abundant expression of mnp2 in aspen corresponded to …

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Detection And Classification Of Buried Radioactive Materials, Wei Wei Dec 2011

Detection And Classification Of Buried Radioactive Materials, Wei Wei

Theses and Dissertations

This dissertation develops new approaches for detection and classification of buried radioactive materials. Different spectral transformation methods are proposed to effectively suppress noise and to better distinguish signal features in the transformed space. The contributions of this dissertation are detailed as follows. 1) Propose an unsupervised method for buried radioactive material detection. In the experiments, the original Reed-Xiaoli (RX) algorithm performs similarly as the gross count (GC) method; however, the constrained energy minimization (CEM) method performs better if using feature vectors selected from the RX output. Thus, an unsupervised method is developed by combining the RX and CEM methods, which …

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Measurement Of Trace Environmental Contaminants Using Cavity Ringdown Spectroscopy, Susan Theresa Scherrer Dec 2011

Measurement Of Trace Environmental Contaminants Using Cavity Ringdown Spectroscopy, Susan Theresa Scherrer

Theses and Dissertations

Environmental contamination has become a significant threat to the health and well-being of mankind as well as to the environment, prompting the establishment and implementation of stringent environmental regulations. The ability to accurately detect and quantify contaminants, such as mercury (Hg), uranium (U), and volatile organic compounds (VOCs), in real-time, in situ is of significant importance to monitoring and remediation efforts. In an effort to develop a real-time, fast-response detector that is portable, highly sensitive, and cost efficient, this research explored the feasibility of utilizing cavity ringdown spectroscopy (CRDS) in conjunction with various plasma sources and vacuum cavities to accurately …

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Development Of A Novel Approach To Assess Qualitative And Quantitative Dynamics Associated With The Subcutaneous Or Intramuscular Administration Of Pharmaceuticals And Associated Parenteral Delivery Systems, Eric Edwards Dec 2011

Development Of A Novel Approach To Assess Qualitative And Quantitative Dynamics Associated With The Subcutaneous Or Intramuscular Administration Of Pharmaceuticals And Associated Parenteral Delivery Systems, Eric Edwards

Theses and Dissertations

There has been a significant increase in the number of injectable pharmaceutical products over the last decade that have been incorporated into unique delivery systems such as pen injectors, auto-injectors, or pre-filled syringes. The advancement of these delivery systems and the paradigm shift towards administration of injectables in the out-of-hospital or home setting have introduced variables that can affect the bioavailability of injectable drugs and potential pharmacologic outcomes. An approach that allows for the qualitative and quantitative dispersion assessment of an injectable at the moment of tissue deposition coupled with an assessment of systemic exposure parameters could provide substantial information …

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Evaluation Of Brook Trout (Salvelinus Fontinalis) Introductions And Re-Introductions Into Four Virginia Blue Ridge Mountain Streams, Michael Isel Iii Dec 2011

Evaluation Of Brook Trout (Salvelinus Fontinalis) Introductions And Re-Introductions Into Four Virginia Blue Ridge Mountain Streams, Michael Isel Iii

Theses and Dissertations

Approximately 100 brook trout were transplanted into each of four Virginia streams in September 2008. Garth Run and Kinsey Run were re-introductions, and Wildcat Hollow and Sweet Run were new introductions. Single pass electrofishing (EF) surveys were conducted with a backpack electrofisher five times during the study. Selected trout > 70 mm but < 100 mm and all trout > 100 mm received a Biomark® 134.2 kHz passive integrated transponder (PIT) tag to identify individual fish upon recapture. Trout were present in all streams almost three years post introductions. Catches decreased across the first four surveys. Young of year catch rates severely decreased from June 2009 (n = …

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Synthesis And Characterization Of Highly Porous Borazine-Linked Polymers Via Dehydrogenation/Dehydrocoupling Of Borane-Amine Adducts And Their Applications To Gas Storage, Karl Jackson Dec 2011

Synthesis And Characterization Of Highly Porous Borazine-Linked Polymers Via Dehydrogenation/Dehydrocoupling Of Borane-Amine Adducts And Their Applications To Gas Storage, Karl Jackson

Theses and Dissertations

A new class of porous polymers has been designed and successfully synthesized by thermal dehydrogenation of several polytopic arylamine-borane adducts and has been designated Borazine-Linked Polymers (BLPs). The polymers reported are constructed of linear, triangular, and tetrahedral amine building units to form 2D and 3D frameworks. The boron sites of the pores are aligned with hydrogen atoms contrasted with the recently reported halogenated BLPs which consist of pore channels aligned with bromine or chlorine atoms. One of the reported BLPs, BLP-2(H), was proven to be crystalline by PXRD, matching the experimental pattern to theoretical patterns calculated from modeled structures. BLPs …

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Regulation Of High Light Responses In Synechocystis Sp. Pcc6803, Waqar Majeed Dec 2011

Regulation Of High Light Responses In Synechocystis Sp. Pcc6803, Waqar Majeed

Theses and Dissertations

Cyanobacteria have evolved various acclimation mechanisms to enable them to thrive under harsh environmental conditions. There are a total of more than 80 sensory kinases and response regulators on the genome of the cyanobacterium Synechocystis sp. PCC 6803, which coordinate the molecular responses to changes in environmental conditions. However, it is not clearly understood how these regulators control the stress-responsive genes. This dissertation focuses on analysis of the functions of two regulators, RpaA and DspA, by targeted mutagenesis. Upon deletion of RpaA, a significant reduction in chlorophyll fluorescence from photosystem I at 77K was observed in whole cells and the …

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