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Comparing Various Physiological System Adaptations Following 8 Weeks Of Resistance Training With Or Without Bfr In Older Males, Ricardo Parra

Theses and Dissertations

PURPOSE: The purpose of this study was to compare the effects of 8 weeks of resistance exercise training with and without BFR on: 1), arterial elasticity and hemodynamics (e.g., blood pressure and resting heart rate), 2) muscular force production (e.g., maximal voluntary contraction, force production, electromyography, and estimated one-repetition maximum) in males between the 50 to 70 years of age.

RESULTS: Significant condition difference for reflection magnitude occurred in BFR group (p < 0.05). Significant time*condition effect occurred in Leg Press 1RM, Leg Extension 1RM, Leg Curl 1RM, Chest Press 1RM, and Shoulder Press 1RM (p < 0.05). Significant condition* time interaction occurred for Isokinetic Leg Extension Test (60°/s) (p < 0.05). A significant time*condition interaction occurred during Maximal Voluntary Contraction (MVC) – Root Mean Square for both vastus medialis and vastus lateralis (p < 0.05). A significant time main effect occurred in the BFR group for the amplitude mean of the MVC in the vastus medialis and vastus lateralis (p < 0.05). A significant time main effect occurred for median frequency of the MVC (p < 0.05). A significant difference in Estimated Visceral Adipose Tissue occurred in the BFR group (p < 0.05). A significant condition*time interaction occurred in arm fat percentage (p < 0.05). The BFR group had significantly less fat tissue (%) in the left arm (p < 0.01) and in the right arm (p = 0.04). A significant time*main effect occurred in the total lean tissue for the left side of the body (p = 0.04).

CONCLUSION: Using BFR resistance training at a low intensity can achieve similar adaptations seen at high intensities while reducing the risk of injury that comes with heavier loads.

Biological Sex Differences In The Monodelphis Domestica: Investigating Behavioral Responses In Environmental Enrichment And Conditioned Place Preference Paradigms, Katelynn M. Renteria

Theses and Dissertations

The Monodelphis domestica, commonly known as the grey short-tailed opossum, has become an increasingly frequented animal model for areas of psychological study, including comparative psychology. Despite the growing interest in utilizing the Monodelphis as an animal model, several areas of research remain limited in what has been studied. This includes associative learning and the effects of environmental enrichment on the Monodelphis. This study novelly incorporates the two using environmental enrichment with the conditioned place preference (CPP) paradigm to both diversify associative learning literature and expand existing knowledge on the Monodelphis domestica. The CPP paradigm included interactive objects as environmental …

Cellular Migration As A Function Of Magnetic Field Intervention, Amy Marie Vecheck

Theses and Dissertations

This work aims to assess cellular migration in three-dimensional structures as a function of Zeeman resonance. By using Zeeman resonance to initialize intersystem crossing of electrons, also known as the Radical Pair Mechanism, bioenergetics processes would be modulated. Processes such as oxygen consumption rate and extracellular acidification rate are indicative of cellular respiration and glycolysis and can be altered based on the orientation of the magnetic field applied: parallel and perpendicular, respectively. This study focused on the parallel orientation and looked to used Zeeman resonance to increase flavin adenosine dinucleotide, which results in preventing the breakdown of F-actin. Cellular viability …

Age-Related Differences In Food-Specific Inhibitory Control: Electrophysiological And Behavioral Evidence In Healthy Aging, Whitney D. Allen

Theses and Dissertations

The number of older adults is estimated to double from 52 million to 95 million by 2060. Approximately 80-85% of older adults are diagnosed with a chronic health condition. Many of these chronic health conditions are influenced by diet and exercise, suggesting improved diet and eating behaviors could improve health-related outcomes. One factor that might improve dietary habits in older adults is food-related inhibitory control. We tested whether food-related inhibitory control, using behavioral (response time, error rate) and scalp-recorded event-related potential (ERP; N2 and P3 components) measures of food-related inhibitory control differed between younger and older adults over age 55. …

Using Movement To Infer Critical Life History Events In Mule Deer: Parturition And Natal Dispersal, Tabitha A. Hughes

Theses and Dissertations

The advent of GPS tracking technology has revolutionized the field of wildlife research. The ability to obtain fine-scale location data from collared animals allows for increased understanding of life-history events that have previously been difficult to research. An excellent candidate species for telemetry-based research is mule deer (Odocoileus hemionus). Mule deer are an important species economically due to their position as a harvested species. Additionally, they play an important role in the ecosystems they occupy; therefore information regarding important life history events would improve conservation and management efforts for this species. Our objectives were to use GPS tracking technology to …

Localized Heat Therapy Improves Mitochondrial Function In Human Skeletal Muscle, Erik D. Marchant

Theses and Dissertations

Physical activity results in various types of stress in skeletal muscle including energetic, oxidative, and heat stress. Acute exposure to stress impairs skeletal muscle mitochondrial function. In contrast, chronic intermittent exposure to mild stress through exercise training results in increased mitochondrial content and respiratory capacity. While oxidative and energetic stress have received much attention regarding their long-term effect on skeletal muscle mitochondria, heat stress is not well understood. The purpose of this work was to investigate the effects of localized heat therapy on human skeletal muscle mitochondria, and to compare these effects to those of high-intensity interval exercise training. To …

Older Adults Home-Based Care In Cairo: Asset Mapping Towards Community Development, Yomna El-Taweel

Theses and Dissertations

The health and economic consequences of the rapid growth of the older adults’ population above 60 have led to new and more flexible forms of care, including home-based care. In Cairo, Egypt, there seems to be a high demand and preference for home-based care services over other care services like nursing homes. From a policy makers’ perspective, older adults’ needs are sometimes approached in a deficit-oriented way. This might contribute to the disempowerment of older adults and make them feel like people with needs that can only be met by external support. This mixed-method study aimed to contribute to the …

Monitoring Of Foraging Sites For Ungulates Within Alpine Plant Communities And Establishment Of Long-Term Monitoring Plots For Rare Castilleja Parvula Var. Parvula In The Tushar Mountains, Utah, Heather Shipp

Theses and Dissertations

The Tushar Mountains of Utah provide essential alpine habitat to a variety of flora and fauna, including 27 endemic plant species and several ungulates (mountain goats, deer, elk, cattle). These ungulates were observed throughout two growing seasons and field analyses were conducted to assess foraging selection. Overall, most ungulates, especially large nursery herds, tended to prefer foraging amongst alpine regions within the Bullion volcanic of the Tushars, which is characterized by denser vegetation than the Belknap volcanic region. Mountain goats and deer were most frequently observed foraging within the Tushar alpine habitat; however, elk and domestic cattle were also observed. …

Implementation Of A Genome-Wide Survey Of Induced Mutations To Identify Agronomically Valuable Variants In Chenopodium Quinoa, Andrew Alarcon Parker

Theses and Dissertations

Quinoa has been utilized for millennia in the Andes region of South America as a nutritious and hardy food crop. In recent years interest in quinoa has grown as need increases for an alternative to traditional cereal crops that can tolerate marginal environments while offering superior nutrition. Growers outside the Andes have experienced several complications adopting quinoa, including undesirable secondary metabolites, poor yield, lodging, and height inconsistency. Unfortunately, access to native ecotypes for crop improvement is limited, and desirable traits are difficult to introduce into available quinoa cultivars because of its allotetraploid genome and tendency to self-pollinate. A genome-wide survey …

Self Reported Cardiovascular Health And Health Behaviors In Women Veterans, Seth Byland

Theses and Dissertations

Objective: The purpose of this study is to describe self-reported cardiovascular health (CVH) and health behaviors in women veterans (WV). A cardiovascular score will be adapted from the existing American Heart Association CVH score. This score will be used to describe CVH in WV.

Methods: Data was collected from WV using an anonymous online survey. This survey asked questions about CVH, CVH behavior, and military specific questions. CVH scoring was determined by asking 6 questions that scored individuals for a total score from 0 to 12, with 12 being most ideal for CVH health. Scores were tallied and mean scores …

Exploration Of The Role Of Neighborhood Residential Segregation By Race And Ethnicity In Obesity Risk Among School-Aged, Melissa L. Fair

Theses and Dissertations

Youth obesity prevalence remains high, despite decades of intervention. Grounded in the social ecological model, neighborhoods and schools are important settings in addressing the complex systems that influence obesity. Contributing to disparities, by race/ethnicity, Black and Hispanic youth are more likely to live in segregated neighborhoods and attend segregated schools, which are also more likely to have high rates of poverty and are less likely to have high quality nutrition and built environments. Leveraging data from local school district (district and state department of education) and national datasets (ACS, Childhood Opportunity Index 2.0), this study examined the associations between school …

Perspectives About Food Safety In Diverse Low- And Middle-Income Countries, Sejla Isanovic

Theses and Dissertations

Concerns about unsafe food influence food choice, and consumption of unsafe foods increases morbidity and mortality, particularly in low- and middle-income countries. Actions to ensure safety of food are dominated by mitigation of biological and chemical hazards through supply-side risk management, disregarding individuals’ experiences and perspectives of food safety. We aimed to identify and categorize perspectives about food safety in five countries. Five Drivers of Food Choice projects provided transcripts from 17 focus groups discussions and 303 interviews in Kenya, Ghana, India, Guinea, and Vietnam. We analyzed transcripts using a priori and emergent codes. Individuals constructed meaning about food safety …

Understanding The Genomic Influence And Virulence Capabilities Of Environmentally Isolated Vibrios, Shannon Elizabeth Pipes

Theses and Dissertations

The genus Vibrio consists of Gram-negative bacteria that possess a curved rod shape and are routinely isolated from estuarine and coastal salt water. Vibrio cholerae, Vibrio parahaemolyticus, and Vibrio vulnificus are the major three species that contribute to human disease worldwide, and a variety of other Vibrio species contribute to persistent problems in the aquaculture and fishing industries. The CDC estimates that vibrios cause 80,000 cases of disease each year in the United States alone, however, this number is thought to be underestimated, since some disease is only self-limiting, meaning patients may not seek medical treatment and have …

Predicting Lower Body Soft Tissue Injuries In American Football With Gps Data, Nicholas Tice

Theses and Dissertations

It is of utmost importance to sports organizations that they keep their players as healthy as possible and contributing to the success of the team. Advancements in technology and investments by sports clubs have allowed researchers to better understand the role of load management in high-level athletes to mitigate injury risk. Through GPS tracking data provided by a collaborating Division I American college football team, we seek to predict lower body soft tissue injuries in future training sessions and reduce the number of potentially avoidable injuries within the organization. The difficulty of analyzing the injury data set is that the …

S-Equol: A Novel Therapeutic For Hiv-1 Induced Gut Dysbiosis, Mason T. Rodriguez

Theses and Dissertations

HIV-1 infection affects approximately 38 million people around the world. The advent of cART has greatly improved the quality of life of infected individuals; however, roughly 50% of these individuals will still experience HIV-1 associated neurocognitive disorders (HAND). Additionally, the gut microbiome has been reported to be dysbiotic in HIV-1 infected individuals, regardless of adherence to cART. Current research has pointed to the gut-brain-microbiota axis as a potential target to treat both cognitive deficits and microbial changes. The present study investigated S-equol (SE) as a potential therapeutic for HAND by modulating the gut microbiome. The study included 21 HIV-1 Tg …

Mining For Progress: Copper, Conflict, And Corporate Social Responsibility, Fritz Culp

Theses and Dissertations

My dissertation examines how transnational mega-mines efface non-Western ways of knowing and being from the Andes. A growing branch of research is questioning the socio-environmental impacts of mining and the influence of regulatory institutions. Despite remarkable scholarship on the ongoing environmentalism of modern-mining, little critical attention has been given to the industry’s pivot to ‘sustainable’ development and its objectives that remain epistemologically centered on the West. My project addresses these gaps by examining Las Bambas—a large-scale copper mine located in South-Central Peru—and its contrasting objectives that emphasize both environmental ‘conservation’ and the ‘modernization’ of non-Western spaces. Building upon the critical …

Homestead Vegetable And Poultry Production And Related Practices: An Assessment In Nepal, Shiva Bhandari

Theses and Dissertations

Consumption of nutrients-rich foods like diverse vegetables, eggs, and meat throughout a year remains a challenge in low- and middle-income countries due to poor availability, accessibility, and affordability. One important way to overcome the challenge is to promote households’ own production of these foods and encourage individuals to consume. Improving household production of the foods necessitates understanding whether active participation and performance of frontline workers in the communities and performing improved production-related practices can translate into improved production of nutrients-rich foods. This study had two specific aims. The first aim was to examine demographic, socio-economic, and programmatic determinants of active …

Moderating Effects Of Parental Feeding Practices And Emotional Eating On Dietary Intake Among Overweight African American Adolescents, Mary Quattlebaum

Theses and Dissertations

This study examined the effects of parental feeding practices and adolescent emotional eating (EE) on dietary outcomes among overweight African American adolescents. Based on Family Systems Theory, it was hypothesized that parental feeding practices, such as parental monitoring and responsibility, would buffer the effects of EE on poor dietary quality, whereas practices such as concern about a child’s weight, restriction, and pressure-to-eat would exacerbate this relationship. Adolescents (N = 127; Mage = 12.83 ۫.74; MBMI % = 96.61 ± 4.14) provided baseline data from the Families Improving Together (FIT) for a Weight Loss trial and an ancillary study. Dietary outcomes …

Associations Between Child Characteristics And Maternal Mental Health In Families Of Children With Autism, Fragile X Syndrome, And Autism Associated With Fragile X Syndrome, Tiffany Nicole Worley

Theses and Dissertations

The present study examined the association between various child characteristics and maternal mental health concerns in three high-risk groups of mothers ± those of children with non-syndromic autism spectrum disorder (NSASD), mothers of children with fragile X syndrome (FXS), and mothers of children with fragile X syndrome and autism (FXS+ASD). Research has shown that mothers of children with NSASD and FXS are thought to share a degree of genetic vulnerability to mental health concerns it is key to examine the various other factors that may contribute to difficulties within the family system and maternal stress, depression, and anxiety.

Participants for …

The Submission Of A Section 513(G) Request For Information, Morgan Ashley Lano

Theses and Dissertations

The Food and Drug Administration designates all medical devices into one of three general classes contingent on their intended use, indications for use, and potential risk to the user. This classification dictates the further path the device must take to be approved for the commercial market. Section 513(g) of the Federal Food, Drug, and Cosmetic Act (21 U.S.C. 360c(g)) is submitted in order to gain the agency’s unofficial classification and suggested regulatory requirements. The Coagulation Companion (MicroVide) is a device designed to fluorescently quantify a key enzyme involved in the coagulation cascade, plasmin, in pediatric patients. clot formation and degradation …

“That Was Denied Thee On Earth”: An Intersectional Bioarchaeology Of Institutionalized Euro-American Women Throughout 19Th And 20Th-Century America, Madeline Maria Atwell

Theses and Dissertations

In the mid 19th-century, American state-supported insane asylums, later renamed state mental hospitals in the 20th-century, were constructed to house and humanely treat individuals perceived to be socially deviant or mentally and physically ill. Women were particularly vulnerable to undue institutionalization because of the prevailing patriarchal gender ideology within medical and colloquial spheres that contributed to the perception that they were biologically pathological. This dissertation interprets the findings of combined archival, historical, and osteological analysis from two U.S. skeletal collections: The Colorado State Insane Asylum (CSIA) Collection and the Hamann-Todd Human Osteological Collection (HT), to examine the embodied, physiological impact …

Longitudinal Relation Of Dietary Quality And Hemoglobin A1c In Youth And Young Adults With Diabetes, Hope Bercaw

Theses and Dissertations

Background Hemoglobin A1c (HbA1c) is a clinical measure of glycemic control among people with diabetes and is associated with health outcomes such as cardiovascular disease. It is possible to decrease HbA1c by improving diet, but it is largely unknown which dietary components are most important in targeting glycemic control.

Objective This study aims to examine whether changes in diet quality across diabetes duration, assessed with the 2015-Healthy Eating Index (HEI), are associated with HbA1c in youth and young adults (YYA) with type 1 (T1D) and type 2 diabetes (T2D). Additionally, we aim to assess whether these relationships differ when dietary …

Nutritional Messaging: To Eat Or Not To Eat?, Christina Triptow

Theses and Dissertations

There is a great deal of diet-specific processed foods on the market today. With so many options it can become difficult for consumers to decide what products to purchase. This situation is further intensified by the plethora of contradictory messages found in food advertising, especially in weight loss and dieting food advertising, but also seen in government nutrition campaigns and all over the internet on platforms like social media, blogs, and so forth. These messages can be confusing and frustrating for consumers as they try to decipher which foods they should eat to reach their health or weight loss goals. …

The Inhibition Of Valproic Acid-Induced Negative Neurodevelopmental Outcomes Through Nrf2-Mediated Redox Regulation, Ted Brenton Piorczynski

Theses and Dissertations

Valproic acid (VPA) is a commonly prescribed antiepileptic drug that causes negative neurodevelopmental outcomes, including neural tube defects (NTDs) and neurodevelopmental disorders, in fetuses exposed to it. While the exact mechanism by which VPA causes defects is unknown, research has shown that VPA increases the production of reactive oxygen species (ROS) that lead to redox dysregulation. We hypothesize that VPA causes negative neurodevelopmental outcomes through the disruption of redox-sensitive signaling pathways that are critical for proper embryonic development, and that protection from the VPA-induced redox disruption may decrease the prevalence of the observed defects. Time-bred mice were treated with 3H-1,2-dithiole-3-thione …

Evaluation Of Bmi, Diet Quality, Alcohol Intake, And Physical Activity In Cancer Survivors: Is There An Association With Primary Source Of Nutrition Advice?, Zachary J. Heindl

Theses and Dissertations

Objective: The purpose of this study was to determine if cancer survivors are meeting nutrition and physical activity recommendations presented by the ACS. The association between a survivor’s primary source of nutrition advice and these factors was also assessed. Method: A sample of 132 cancer survivors was recruited through social media. Inclusion criteria included: United States citizenship, at least 18 years of age, and diagnosis of cancer or malignancy by a health care professional. A one-time, self-administered survey was distributed via Qualtrics. The Dietary Screener Questionnaire was utilized to determine average daily consumption of fruits and vegetables and the weekly …

Relative Energy Deficiency In Sport ( Red -S ) Risk Factors Among Collegiate Athletes, Hope K. Metz

Theses and Dissertations

BACKGROUND: Low energy availability is a topic of concern for recreational and elite athletes alike due to its negative impact on both physiology and performance. The introduction of the Relative Energy Deficiency in Sport model by the International Olympic Committee in 2014 highlighted the widespread effects of poor fueling on an athlete’s overall health. Unfortunately, RED-S is not typically detected until the athlete has already suffered significant health or performance detriments from inadequate calorie intake. PURPOSE: The purpose of this study is to examine the prevalence of risk factors associated with RED-S among collegiate athletes and evaluate the potential need …

The Differential Effects Of Prenatal Exercise Training Type On Maternal Glucose Metabolism: A Secondary Data Analysis Of A Prospective Randomized Controlled Trial, Stephanie Prostko

Theses and Dissertations

Gestational diabetes mellitus (GDM) complicates 10-12% of pregnancies worldwide and poses significant, immediate, and long-term health risks to both the mom and baby. Importantly, consistent research demonstrates participating in sufficient levels of exercise during pregnancy may effectively manage maternal glucose levels, thereby potentially decreasing the risk of GDM. Most of these studies however, restricted their investigations to exposing pregnant women only to aerobic exercise. Previous studies in non-pregnant populations showed various exercise training types, such as resistance and combined (resistance + aerobic) training, elicited positive, independent effects on glucose metabolism, yet similar effects in pregnant women are unclear. PURPOSE: To …

The Effects Of Victimization And Trauma On Well-Being, Physical Health Nutritional Habits, And Resting Heart Rate (Rhr) Based On Gender And Sexual Orientation, Mary Hannah Hughes

Theses and Dissertations

There is a well-established and growing body of research dedicated to understanding the influence of past victimization on physical health outcomes. Consequently, knowledge on identifying how past victimization types influence each domain of physical health and if these outcomes differ by gender and sexual orientation remains largely absent within literature. Therefore, the purpose of the following study is to expound upon victimization literature by examining the physical health outcomes associated with different victimization types and to examine how these factors differ by both gender and sexual orientation with regard to victimization type (personal, property, and stalking). Guided by both life-course …

Evaluating Nutrition Knowledge In Parents And Its Relation To Childhood Obesity, Rachael Shangraw

Theses and Dissertations

This study aims to evaluate the relationship between parental nutrition knowledge and their child’s body mass index (BMI) to identify variables that are associated with increased obesity in American children. A cross-sectional study design was employed with a convenience sample of 464 parents of children between the ages of 2 and 12. Parents completed a GNKQ-R (General Nutrition Knowledge Questionnaire – Revised) survey to measure nutrition knowledge. Parents reported their child’s height and weight which was later calculated and categorized according to the Center for Disease Control’s BMI-for-age growth chart. The Kolmogorov-Smirnov Test for Normality was conducted to examine the …

Behavioral And Physiological Effects Of Heavy Metals On Fish: A Review And Preliminary Results, Diana V. Morales

Theses and Dissertations

Pollution, specifically heavy metal pollution, in various bodies of water has been a significant issue for decades. Research has been conducted on heavy metals and their effects on the environment, larger fish species, and humans since the 1970s (Skidmore, 1964; Adeniyi et al., 2007; Adeosun et al., 2015; Bawuro et al., 2018). It is known that zinc is a neurotoxin in some species and causes harm to the environment. It is also known that it causes harm to people if it is ingested or if they are exposed to it for long periods of time (Mahurpawar, 2015; Mizuno and Kawahara, …