Digital Commons Network^™

Establishing Sustainable Community Garden Interventions With Aid From Health Promotion Organizations, Rachel Joann Buenemann

Theses and Dissertations

Community garden interventions provide policy, system and environmental change at the community level to establish health behaviors, which act in contest to obesity risk factors. Limited research examines factors, which influence the sustainability of community garden interventions. Therefore, in this study, a sample of 10 Midwestern community gardens associated through funding from a health promotion organization in 2013, collected data through the interviewing and surveying of 10 garden administrators and surveying of 12 garden volunteers. The study identified garden benefits perceived by garden administrators and volunteers to include contributions to social justice, continued education, enhanced social cohesion, increased access to …

Do Healthcare Professionals With High Weight Biases Provide Different Quality Of Care To Obese Compared To Normal Weight Patients?, Justine Leigh Seymour

Theses and Dissertations

Though weight bias has been acknowledged in the health field, it is less understood if and how weight bias affects quality of care. The purpose of this study was to determine if weight bias exhibited by healthcare professionals (HCPs) impacts quality of healthcare provided to obese individuals. HCPs (n=220; 88% female, 87% nurses) in the Midwest region of the United States were recruited to complete an online survey. Participants completed the Attitude Towards Obese Persons scale (ATOP) to assess weight bias and responded to hypothetical patient scenarios to evaluate quality of care. A median split was calculated for ATOP scores …

Predicting Cardiovascular Fitness In Ethnic Minority Youth: A Comparison Of Demographic, Body Composition, And Physical Activity Variables, Steven Arcidiacono

Theses and Dissertations

Prevalence of obesity, low physical activity, and poor physical fitness of youth in the United States are increasingly poor and in need of intervention to prevent later concerns like hypertension. The overall goal of this dissertation was to examine which factors weigh heaviest in predicting cardiovascular fitness in diverse youth, and how we might measure those factors by maximizing clinical utility and psychometric properties. The sample was gathered from a larger study examining physical activity in youth from Miami-Dade county enrolled in out-of-school programs. Participants (N = 58) were aged 6-17 and comprised exclusively of Hispanic and Non-Hispanic Black children …

Ptsd Subtypes, Depressive Presentation, Dissociation, And Cognitive Appraisals And Their Impact On Cardiovascular Reactivity Responses To Stress, Dyona Augustin

Theses and Dissertations

Both posttraumatic stress disorder (PTSD) and major depressive disorder (MDD) are related to an increased risk for cardiovascular disease (CVD), with links to ischemic heart disease, myocardial infarction, cardiac mortality, and other cardiac conditions. Given that these disorders are associated with increased medical costs, disability, and employer burden, research has investigated which factors increase the likelihood that one will develop CVD. While one hypothesis suggests that individuals who exhibit exaggerated responses to stress are at greater risk of developing CVD, individuals with PTSD/depression have been shown to exhibit both exaggerated and blunted stress responses. The purpose of the present study …

The Impact Of Objective Quality Ratings On Patient Selection Of Community Pharmacies: A Discrete Choice Experiment And Latent Class Analysis, Julie A. Patterson

Theses and Dissertations

Background: Pharmacy-related performance measures have gained significant attention in the transition to value-based healthcare. Pharmacy-level quality measures, including those developed by the Pharmacy Quality Alliance, are not yet publicly accessible. However, the publication of report cards for individual pharmacies has been discussed as a way to help direct patients towards high-quality pharmacies. This study aimed to measure the relative strength of patient preferences for community pharmacy attributes, including pharmacy quality. Additionally, this study aimed to identify and describe community pharmacy market segments based on patient preferences for pharmacy attributes.

Methods: This study elicited patient preferences for community pharmacy attributes …

Buy For The Sake Of Your Baby: Guardian Consumerism In Twentieth Century America, Mark Vandriel

Theses and Dissertations

“Buy For the Sake of Your Baby” argues that consumerism for infants in twentieth century America was an exceptional type of consumer society. Because the parents who bought the consumer goods could not effectively communicate with their children who used these products, parents frequently purchased items for their babies as acts of good parenting. These parent consumers wanted to do what was right for their children, but because they could not effectively communicate with their children, they were particularly susceptible to influence from outside groups. Businesses, nongovernmental organizations, and the federal government recognized throughout the twentieth century how to effectively …

The Role Of Exercise Dose On Ghrelin Concentration In Postmenopausal Women, Kimberly Bowyer

Theses and Dissertations

Introduction: As obesity continues to be a major public health concern, exercise is continually at the forefront of combating this epidemic. This thesis aims to examine how two different doses of exercise may affect the “hunger hormone”, ghrelin; in postmenopausal, non-obese women. Methods: 54 non-obese postmenopausal women were randomly assigned to either a higher dose (energy expenditure = 14 kilocalories/per kilogram of body weight/per week) or lower dose (energy expenditure = 8 kcal/kg/week) aerobic exercise training group for 16 weeks. Fasting blood samples were taken at baseline and at post intervention for analysis of ghrelin via multiplex immunoassay. Results: Only …

Association Of Freestanding Dialysis Facility Size, Quality Incentive Program Scores And Patient Survival, Fozia Ajmal

Theses and Dissertations

Background

In 2011, The Centers for Medicare and Medicaid Services (CMS) has introduced a bundled payment reform along with a Quality Incentive Program (QIP) to bring efficiency in End stage renal disease (ESRD) care. The QIP rates facilities using clinical and reporting criteria, but misses out on patient outcomes. It penalizes facilities not achieving a target score by 0-2% of payments. The small facilities are expected to be impacted more by a reduction in payments. We determined the association between ESRD facility size and QIP scores and the association between QIP scores and patient survival.

Methods

We used the Medicare …

Best Practice For Screening Adult Patients With Psoriasis For Polyautoimmunity: Celiac Disease, Rheumatoid Arthritis And Crohn’S Disease, Susan Danielle Ashbaugh

Theses and Dissertations

The purpose of this quality improvement project was to determine if screening primary care patients with psoriasis will improve early detection of celiac disease (CD), rheumatoid arthritis, and Crohn’s disease (CrD). The aim of this project is to assess the utility of early screening in patients with psoriasis in order to facilitate earlier diagnosis of CD, RA and CrD, which would consequently initiate earlier treatment and improve long-term patient outcomes. Genetic and population-based studies suggest that individuals with psoriasis have a greater risk of also having CrD, CD or RA, than do individuals without psoriasis. The literature also suggests that …

The Regulation Of Glycoprotein130 Dependent Inflammatory Cytokines One Basal And Mechanical Stimuli Induced Protein Synthesis In Myotubes And Skeletal Muscles, Song Gao

Theses and Dissertations

Maintaining skeletal muscle mass has a well-documented role in health and quality of life. Two members of IL-6 family of cytokines, IL-6 and LIF, and have a paradoxical role in skeletal muscle mass regulation: short term elevation of IL-6 and LIF plays a key role in mechanical stimuli induced muscle growth and muscle hypertrophy, while the long term elevated IL-6 and LIF regulate muscle wasting during cancer cachexia by disrupting muscle protein turnover regulation. The regulation of muscle protein synthesis is an important determinant of mechanical stimuli induced muscle hypertrophy and muscle wasting during cancer cachexia. IL-6 family of cytokines …

Embodied Madness: Contextualizing Biological Stress Among 19th And 20th-Century Institutionalized Euro-American Women, Madeline M. Atwell

Theses and Dissertations

The late 19th and early 20th-centuries in the United States were periods in which white women of middle and low socio-economic status were admitted into insane asylums at a higher rate than men for the first time in recorded history. An existent body of literature helps us to comprehend the social and cultural climate in which the institutionalization of women was both acceptable and commonplace; yet few studies have paired this research with the information that can be revealed on the bones of those institutionalized. A sample of 53 institutionalized women from the Robert J. Terry Anatomical Collection were analyzed …

Losing Weight With Five A’S (5 A’S): Assess, Advise, Agree, Assist, Arrange Framework And Motivational Interviewing (Mi) For Health Behavior Change Counseling, Jacqueline Baer

Theses and Dissertations

According to the Centers for Disease Control and Prevention (CDC), obesity has reached epidemic levels and has associated with increased risk of morbidity and mortality rates. The increasing prevalence of obesity is a major public health concern. Researchers calculate that health care costs are 44% higher among moderately and severely obese older persons than for persons at normal weights. Seventy-five percent of African American (AA) women are overweight and obese according to data from the CDC and The State of Obesity: Better Policies for a Healthier America. Compared to any other racial ethnic group, AA women are more likely to …

Prenatal Methylmercury Exposure Through Rice Consumption In Rural China, Chuan Hong

Theses and Dissertations

Background: Methylmercury is one of the most toxic forms of mercury, which severely afflicts the developing fetus. Methylmercury exposure occurs not only through fish consumption but also through rice consumption. However, rice does not contain the same beneficial micronutrients that fish/shellfish has. Therefore, prenatal methylmercury exposure through maternal rice consumption may potentially increase adverse health effects on the developing fetus.

Objectives: The purpose of this dissertation was to investigate the magnitude of prenatal methylmercury exposure through rice consumption and the relationship between maternal mercury biomarkers and birth outcomes.

Methods: A total of 398 pregnant women were recruited at parturition in …

Depressive Symptoms Association With Health Outcomes And Treatment In Older Americans With Diabetes, Lashonda Jovon Williams

Theses and Dissertations

Introduction: Diabetes remains the 7th leading cause of death in the United States. Diabetes is a major public health concern of its own, but when you add the comorbidity of depression, diabetes outcomes are amplified. This dissertation examines how depressive symptomatology and treatment for depression are associated with selfreported health (SRH) and diabetes control.

Methods: Chi-square and logistic regression were used to analyze data from the Health and Retirement Study (2012). We assessed the associations between SRH and diabetes control with depressive symptomatology data.

Results: In our sample (n=4374), 19% of respondents reported high depressive symptomatology and …

Early Life Factors And Health Outcomes In Children And Mothers, Olubunmi Olufunke Orekoya

Theses and Dissertations

This dissertation focused on early life exposures and their impact on children and mothers’ health. It consists of three distinct studies with an overarching goal of understanding how early life factors influence health outcomes among children and mothers. The broad aims are: 1) to examine the association between maternal gestational weight gain and offspring weight at 1 year, while assessing the mediating role of birth weight; 2) to determine the association between breastfeeding practices and development of allergic conditions (eczema/skin allergy, hay fever/respiratory allergy, and asthma); and 3) to examine the association between breastfeeding and postpartum weight retention at 12 …

Picturing Rest: A Photovoice Study Of African American Women’S Perceptions And Practices Of Rest, Eboni T. Herbert Harris

Theses and Dissertations

African American women are consistently identified as being less likely to participate in sustained leisure time physical activity (Tussing-Humphreys, Fitzgibbon, Kong, & Odoms-young, 2013), yet more likely to be overweight or obese (Levi, Segal, Laurent, & Rayburn, 2014). There has been a wide range of initiatives directed towards preventing and/or reducing obesity among African Americans, such as targeted physical activity and nutrition interventions involving goal setting, group and individualized counseling, and social support. Previous research focused on African American women’s perceptions toward physical activity, nutrition, and weight; emphasize the consideration of cultural attitudes like placing a high value on rest …

Exploring Spatial Patterning And The Impact Of Obesogenic Built Environments For Youth Obesity, S. Morgan Hughey

Theses and Dissertations

Youth obesity is a major public health concern due to an array of physical, social, and psychological health consequences. Residential location, often referred to as ‘place’, has continued to emerge as a key health determinant with studies showing that where a child lives impacts their health. Environments where it is easy for individuals to have low levels of physical activity – either by discouraging active behavior or promoting sedentary behavior – and easy for individuals to consume unhealthful foods – either by the limited availability of healthful foods or increased availability of unhealthy foods – have been coined ‘obesogenic’. Additional …

Evaluating A Community-Based Program Within Multi-Ethnic Communities: Examining The Outreach And Engagement Program Of Mecca, Sheva Assar

Theses and Dissertations

The present study includes a program evaluation to assess the extent to which a community based multiethnic program, specifically the Outreach & Engagement (O&E) Program of the Multi-Ethnic Collaborative of Community Agencies (MECCA) adhered to Community-Based Participatory Research (CBPR) principles as intended in its development and implementation. A post-reflection discussion, which included questions that were guided by the Community-Based Participatory Research Evidence-Based Curriculum, with the O&E Program Evaluator determined the extent to which each CBPR principle was fulfilled. Thematic findings from the post-reflection discussion highlighted many strengths, as well as areas of improvement within the research-community partnerships. MECCA’s O&E Program …

Success Strategies Of First-Generation Foreign-Born Leaders, Verzhine Julfayan-Gregorian

Theses and Dissertations

The United States of America is a country of immigrants, where people and groups representing different nationalities have immigrated in search of a better life and opportunities. Among those immigrants are the Armenian people, who immigrated to the United States fleeing wars and Genocide. This study explores the first-generation foreign-born leaders of Armenian descent who came to the United States in search of opportunities, education, happiness, and success. The study examines the success strategies employed by first-generation, foreign-born leaders. This phenomenological study concentrates on the common experiences of the selected 15 participants. To answer the four research questions, 15 foreign-born, …

Exploration Of The Impact Of Childhood Obesity And The Correlation With Parents, Emilee L. Leslie

Theses and Dissertations

This review and analysis explored the prevalence of childhood obesity within the United States and other countries around the world, as well as the correlation between childhood obesity and parents. Method: I originally planned to conduct a survey study within the Muscogee-Columbus County School District (MCSD); however, I was unable to get the correct signatures in order to proceed with the Institutional Review Board (IRB) approval process. At that time I got approval from the Honors Dean and my Thesis Director to conduct an in-depth literature review and analysis on the impact of childhood obesity and the correlation with parents. …

When Women Win: Prominent Leadership Traits That Contributed To The Successful Election Of Women In California, Diandra Simone Bremond

Theses and Dissertations

This qualitative study identifies prominent leadership traits that contributed to women’s successful election in California. Moreover, this study discovers how intelligence, self-confidence, determination, integrity, and sociability contribute to California women’s success. The research design was a qualitative narrative study. Women elected officials in local, state, and federal legislatures in California were the participants. The conceptual framework served as a basis for the purpose and research questions. Semi-structured questions were utilized to interview women elected officials in California to identify leadership traits that contributed to their successful election. Following an extensive literature review, an expert panel of researchers ascertained the validity …

Assessing The Well-Being Koreans And Korean Americans: Psychometric Validation Study For A Multidimensional Assessment Of Well-Being, Esther Lee

Theses and Dissertations

Current measures of well-being have most commonly been developed to measure well-being in a manner consistent with how it is conceptualized in individualistic, Western cultures. The Multidimensional Well-Being Assessment (MWA) was developed based on the multidimensional contextual model of well-being and is intentionally culturally inclusive. A non-random sample of 259 Koreans and Korean Americans participated in a study to examine the psychometric properties of the MWA. In addition, a number of demographic variables (e.g., gender, age, immigration status, and financial status) were evaluated to explore correlates of well-being. The MWA demonstrated robust internal consistency as well as strong validity with …

We Shall Overcome: A Phenomenological Study Of The Role Academic, Social And Family Factors Have On English Learners' Decision To Pursue Higher Education, Jennifer L. Huang

Theses and Dissertations

The attainment of a college degree has long been a part of the American dream. For the English learner, however, reaching this goal is a task fraught with difficulty. Yet, as the participants in this study demonstrate, it is possible. In this qualitative, phenomenological study of seven current community college students who graduated from a Southern California high school, not yet proficient in the English language, the researcher sought to identify the factors that both encouraged and discouraged their decision to pursue higher education. This study collected original data on factors within the school setting, peers, family and personal characteristics …

Belle Isle, Point Lookout, The Press And The Government: The Press And Reality Of Civil War Prison Camps, Marlea S. Donaho

Theses and Dissertations

The study of Civil War prisons is relatively new within the broader study of the Civil War. What little study there is tends to focus on bigger prison camps. It has been established in the historiography that prisoners suffered across the divided nation, but it has not been ascertained how the decisions and policies of the government, as well as the role of the press in those decisions, effected the daily lives of Civil War prisoners. Belle Isle, a Confederate Prison, and Point Lookout, a Union prison, will be analyzed for key differences to provide a fuller picture of life …

Characterization Of Staphylococcal Nuclease And Tudor Domain Containing Protein 1 (Snd1) As A Molecular Target In Hepatocellular Carcinoma And Non-Alcoholic Steatohepatitis, Nidhi H. Jariwala

Theses and Dissertations

CHARACTERIZATION OF STAPHYLOCOCCAL NUCLEASE AND TUDOR DOMAIN CONTAINING PROTEIN 1 (SND1) AS A MOLECULAR TARGET IN HEPATOCELLULAR CARCINOMA AND NON-ALCOHOLIC STEATOHEPATITIS

Nidhi Jariwala, PhD

A dissertation submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy in Integrative Life Sciences

Virginia Commonwealth University, 2017

Devanand Sarkar, M.B.B.S., PhD.

Associate Professor, Department of Human and Molecular Genetics

Virginia Commonwealth University

Richmond, Virginia

SND1, a subunit of the miRNA regulatory complex RISC, has been implicated as an oncogene in hepatocellular carcinoma (HCC). Oncoprotein SND1 regulates gene expression at a post-transcriptional level in multiple cancers including hepatocellular carcinoma (HCC). …

The Anatomy Of Cbpr: A Case Study Of Cbpr Implementation For Health Promotion With The Peer Community, Cory R. Cummings

Theses and Dissertations

This case study is a qualitative examination of a health promotion project conducted in collaboration with members of the mental health peer community. More specifically, it explores the community based participatory research (CBPR) implementation process used to conduct this health promotion project to gain a deeper understanding of the mechanisms at work in the implementation process. While there has been considerable attention to the principles that guide CBPR (Braun et al., 2012; Israel et al., 2008; LaVeaux & Christopher, 2009), there remains important work to be done in bridging these principles to implementation; what processes or mechanisms translate these principles …

Amixicile Inhibits Anaerobic Bacteria Within An Oral Microbiome Derived From Patients With Chronic Periodontitis, Kane Ramsey

Theses and Dissertations

Periodontitis is a chronic inflammatory disease caused by pathogenic bacteria residing in a complex biofilm within a susceptible host. Amixicile is a non-toxic, readily bioavailable novel antimicrobial that targets strict anaerobes through inhibition of the activity of Pyruvate Ferredoxin Oxidoreductase (PFOR), a major enzyme mediating oxidative decarboxylation of pyruvate. Our study aimed to evaluate the efficacy of amixicile, when compared to metronidazole, in inhibiting the growth of bacteria present in a microbiome harvested from patients with chronic periodontitis.

Plaque samples were harvested from patients with severe chronic periodontitis and cultured under anaerobic conditions. The microbiomes were grown in the presence …

Come Fly With Me: Using Amixicile To Target Periodontal Pathogens And Elucidating The Innate Immune Response In Drosophila Melanogaster, Kathryn Sinclair

Theses and Dissertations

Periodontal diseases (PD) affect 46% of American adults over age 30. These diseases cause symptoms including bleeding and swelling of the gums, bone resorption, and tooth loss, that affect quality of life and have a high economic burden. Periodontal diseases are caused by an imbalance in the oral microbiome, from a healthy state that contains anti-inflammatory commensals like Streptococcus gordonii and mitis, to a diseased state that has pro-inflammatory anaerobic pathogens including Porphyromonas gingivalis, Prevotella intermedia, Fusobacterium nucleatum, and Tannerella forsythia. The latter initiate disease progression in the oral cavity. However, it’s the host immune …

Service-Learning: An Interpretive Case Study Of Teachers’ Perspectives And Planning Strategies, Cory Susanne Miller

Theses and Dissertations

This interpretive case study focused on elementary teachers who were implementing a service-learning project in their classroom. Research suggests that service-learning is beneficial for students and is becoming more prevalent in high schools and universities. Current literature, however, provides little evidence for the use of service-learning at the elementary level. The purpose of this study was to explore and gain insight in to how elementary school teachers use service learning and to examine underlying factors that shape and influence how teachers plan for and implement service learning projects. This study aims to provide a planning model to support elementary teachers …

Creating Equitable Access Pathways For All Students In South Carolina? A Study Of Sc International Baccalaureate Diploma Programs, Diane D. Padula

Theses and Dissertations

This case study adds insight to the idea of equitable access as it relates to advanced coursework available to students in public high schools in South Carolina. The International Baccalaureate Diploma Program (IBDP) has become a viable choice since secondary-level magnet programs in SC have taken root for over thirty years. The IBDP originally developed in SC to attract the global elite, however in the recent decade, the IBDP has morphed into a program meant for all students. The concept of IB for All is marketed as a college readiness program within South Carolina IBDP schools. Access is multidimensional; it …