Digital Commons Network^™

Development Of Raman Spectroscopic Methods To Analyze Chemical, Biological, And Physical Constituents For Food Safety And Quality, Hannah C. Broadbent

Theses and Dissertations

Ensuring food safety and quality is crucial for consumer health, satisfaction, and regulatory compliance. This study aims to develop rapid, reliable methods for detecting food constituents (i.e. lactose), pathogens (i.e. Listeria monocytogenes), and contaminants (i.e. micro- and nano-plastics) using Raman spectroscopy. With advantages like high specificity, minimal sample preparation, and fast analysis, Raman spectroscopy offers a promising alternative to traditional methods. This research explores its application in assessing chemical, biological, and physical properties of food to enhance safety and quality monitoring. Lactose-free products are increasingly popular due to the global prevalence of lactose intolerance, creating a need for effective verification …

The Impact Of Sensory Sensitivity On Nutritional Outcomes In Children With Neurodevelopmental Disorders, Rachel M. Qualley

Theses and Dissertations

Background/Objective: Children with neurodevelopmental disorders (NDDs) are at increased risk of malnutrition due to restrictive dietary patterns and behavioral difficulties at mealtimes. Research suggests that heightened sensory sensitivity, a characteristic accompanying several of these disorders, may be a contributing factor. However, the effects of sensory sensitivity on nutritional outcomes across distinct NDDs have not been fully explored. This review aims to examine the relationship between sensory sensitivity and nutritional status, food preferences, and eating behaviors in children with NDDs, specifically investigating how atypical sensory processing might influence dietary intake.

Methods: A literature search was conducted using Google Scholar, PubMed, …

Dietary Patterns And Their Effects On C-Reactive Protein Regarding Female Reproductive Disorders, Mckenzie Moe

Theses and Dissertations

Objectives: Chronic inflammation, as indicated by elevated C-reactive protein (CRP), plays a critical role in women’s reproductive health disorders. CRP is one of the most common biomarkers of inflammation. Dietary components, lifestyle factors, and women’s reproductive health disorders are major components that influence the levels of CRP within the body. Other influential factors include injury, infection, and illness. The purpose of this review is to explore the findings of literature available on nutrition interventions for CRP levels in consideration of women's reproductive disorders.

Methods: This narrative review examines the works of 15 articles, including 10 cross-sectional and five longitudinal designs. …

The Role Of Almonds In Exercise Recovery And Athletic Performance, Kathryn M. Trochman

Theses and Dissertations

Objectives: During exercise, many trained athletes and physically active adults experience symptoms of exercise-induced muscle damage (EIMD). The effects of EIMD can cause limitations in athletic performance and increased duration of exercise recovery. Nutritional interventions have shown results in improving the duration of recovery. However, there are few studies completed on common food items. This review aims to examine the role of almonds in exercise recovery and athletic performance. Methods: A literature search was conducted utilizing Google Scholar, PubMed, CINAHL Ultimate, and reference hand searching. The search parameters included the dietary intervention of almonds for trained athletes and physically active …

Development Of A Qualitative Spot Assay For Zinc Detection In Fortified Cereal Grain Matrices, Ashley L. Lamborn

Theses and Dissertations

The present thesis is a compilation of a literature review, journal manuscript, and two standard operating procedures (SOP) on the qualitative determination of zinc in fortified cereal grain products and matrices. The literature review addresses the premise of the research as well as potential solutions for the development of a rapid qualitative spot assay for zinc determination. Quality assurance assays affirm the presence of micronutrients in food fortification initiatives, but no rapid qualitative spot methods for the assessment of zinc currently exist. Chromogenic reagents that may perform a key role in the rapid determination of zinc are identified. The journal …

Analysis Of Nitrogen Accumulation And Gene Expression In Hydroponically-Grown Chenopodium Genotypes, Teal Kalt

Theses and Dissertations

Nitrogen (N) is an essential macronutrient required by all plants to complete their life cycles. Inefficient N uptake contributes to over fertilization and subsequent environmental and sustainability issues resulting in the need for improved nitrogen use efficiency (NUE). Chenopodium quinoa is a resilient pseudocereal crop that is relatively adapted to N-deficient soils. Previous studies have uncovered the unique genetic structure of quinoa and its physiological responses to N availability; however, gaps remain in understanding its molecular mechanisms for NUE. This study investigates four quinoa genotypes (Real-1, 0654, KU-2, and QQ74) hydroponically grown in N-deficient conditions. RNA sequencing (RNA-seq) analysis identified …

Barriers In Receiving A Diagnosis Of Sanfilippo Syndrome: Perceptions From Healthcare Providers And Caregivers, Cassidy Lena

Theses and Dissertations

Sanfilippo syndrome (MPS III) is a rare, degenerative condition characterized by symptoms impacting neurological functioning, behavior, and quality of life. Diagnosis is often not made until three to six years of age, but comprehensive and effective symptom management have been reported to optimize patient longevity. The aim of this study was to identify barriers to diagnosis and the corresponding impact on patients. This study surveyed healthcare providers and caregivers of individuals with Sanfilippo syndrome. Both quantitative and qualitative methods were employed to assess provider knowledge and comfortability in managing Sanfilippo syndrome. Additionally, it explored caregiver perspectives on healthcare system navigation, …

Building Trustable Methods For Group Recommendations: Advancing Fairness And Robustness Across Domains, Siva Likitha Valluru

Theses and Dissertations

On the internet, where the number of available choices for information is exponentially growing, there is a need to prioritize and deliver relevant results to users efficiently, on demand. Recommendation systems (RSs) address that need by searching through and filtering large amounts of dynamically generated information and providing users with recommendations tailored to them. These systems have primarily focused on (1) single-user models, where recommendations are tailored towards a specific individual, or (2) single-item models, where items are recommended based on a broader appeal to users and similarities in item metadata, in the past. In many real-world scenarios, however, recommendation …

Phytochemicals And Human Health, Erin Kelley Richards

Theses and Dissertations

This review explores the intricate relationship between phytochemical intake and human health. It first highlights the contrast between the phytochemical-poor Standard American Diet (SAD) and ancestral diets rich in diverse plant and animal foods. The classification, sources, and health benefits of various phytochemicals, including polyphenols, flavonoids, alkaloids, and terpenes are described and discussed. The bioavailability of these compounds and their interactions with the gut microbiome are elucidated, emphasizing on their potential in modulating multiple pathways associated with aging and chronic diseases. The 12 hallmarks of aging and how phytochemicals may influence these hallmarks are reviewed. While exploring the potential benefits …

The Association Between Parent’S Mobile Device Use And Physical Activity, Sydney Hill

Theses and Dissertations

Background. The rapid increase in mobile technology has allowed smartphones to be used almost anywhere, but a potential disadvantage of these mobile devices is the displacement of physical activity. Parents of young children are already struggling to reach higher intensities of physical activity and mobile devices might make this worse. However, most existing research on similar topics look at adults without children or uses subjective measures only. Therefore, this study aims to (1) quantify objective mobile device use from a sample of parents with preschool age children; (2) describe the duration and intensity of parents’ physical activity and inactive behavior; …

Associations Between Cardiovascular Disease And Utilization Of Dental Preventive And Periodontic Services, Amirhossein Fakhre Yaseri

Theses and Dissertations

Cardiovascular disease (CVD), including coronary artery disease, heart failure, myocardial infarction, and stroke, remains a leading cause of global mortality, with approximately 20.5 million deaths in 2021. Despite advancements in medical science, CVD prevalence continues to rise, underscoring the need for preventive approaches and increased awareness. CVD is closely associated with oral diseases, and poor oral health is linked to worse cardiovascular outcomes. This study investigates the association between CVD and the utilization of dental preventive and periodontal services using data from the Dental Experience and Research Exchange (DERE) database, which aggregates clinical data from dental practices across the U.S. …

The Effects Of Acute Nutrient Intake On Raw Segmental Bioelectrical Impedance Values And Fluid Shifts In Premenopausal Women, Callie Unrein

Theses and Dissertations

Background: Raw bioimpedance measures—impedance (Z), resistance (R), reactance (Xc), and phase angle (PhA)—are emerging tools to assess hydration, cellular integrity, and muscle quality. While multifrequency bioimpedance analysis (MF-BIA) can detect acute physiological shifts, its sensitivity to nutrient intake, especially across hormonal phases in women, remains underexplored. Purpose: This study investigated how essential amino acids (EAA), carbohydrates (CHO), and water (CON) influence postprandial segmental bioimpedance and fluid distribution in healthy women, and whether these responses vary by menstrual hormone phase. Methods: Twenty-two recreationally active women (18–40 years) underwent serial MF-BIA (InBody 970) assessments during high- and low-hormone phases, randomized to one …

From Pregnancy To Postpartum: A Longitudinal Analysis Of Maternal Depressive Symptoms And Hemoglobin Concentration In Uttar Pradesh, India, Abdullah Nurus Salam Khan

Theses and Dissertations

Background: Perinatal depression and maternal anemia impact maternal health, pregnancy outcomes, and infant growth in low- and middle-income countries. This study examines the prevalence and risk factors of these conditions during pregnancy and postpartum in rural Uttar Pradesh, India. Methods: A prospective cohort study was conducted among 475 pregnant women recruited during early pregnancy (≤20 weeks gestation) and followed through late pregnancy (≥27 weeks) and postpartum (< 42 days of childbirth). The outcome variables were, i) depressive symptoms, assessed using the Edinburgh Postnatal Depression Scale (EPDS), and ii) hemoglobin concentrations, measured using HemoCue Hb 301 analyzer from capillary blood. Multivariable linear regression examined associations of the outcome variables with sociodemographic, obstetric, nutritional, interpersonal, and perinatal factors. Path analysis evaluated direct and indirect paths influencing postpartum hemoglobin. Results: Prevalence of probable depression (EPDS score≥13) peaked in early pregnancy (24%) and declined in late pregnancy (17%) and postpartum (4%). Mean hemoglobin declined from early (10.5 g/dL) to late pregnancy (9.7 g/dL), and partially recovering in postpartum (10.4 g/dL). Household food insecurity was associated with higher depressive symptoms during pregnancy and postpartum (early pregnancy:β=2.61, p=0.011; late pregnancy:β=2.84, p< 0.001; postpartum:β=1.40, p=0.023). Psychological intimate partner violence was associated with greater depressive symptoms in early pregnancy (β=3.19, p=0.001). Receiving more antenatal visits was associated with decrease in depressive symptoms in late pregnancy (β=-0.46, p=0.001) and hemoglobin at postpartum (β=-0.11, p=0.070). Consumption of more food groups was associated with increase in depressive symptoms (β=0.63, p=0.004) and hemoglobin in late pregnancy (β=0.10, p=0.026). Iron folic acid (IFA) consumption was associated with increase in hemoglobin in late pregnancy (β=0.01, p< 0.001) and postpartum (β=0.004, p=0.031). Experiencing postpartum health complications was associated with increase in depressive symptoms (β=0.41, p=0.013) and decrease in hemoglobin concentrations (β=-0.18, p=0.036). Antenatal hemoglobin concentrations mediated the associations of IFA supplementation and dietary diversity with postpartum concentrations. Conclusion: Perinatal depression was associated with socioeconomic vulnerabilities, food insecurity, and intimate partner violence, while hemoglobin concentrations were associated with maternal nutrition and perinatal care. Integrating mental health services and comprehensive nutrition interventions into antenatal and postpartum care can improve psychological and physical well-being of mothers during and after pregnancy.

The Role Of B Cells In Promoting Lipid Absorption By Promoting Lacteal Development, Kenny Johnson

Theses and Dissertations

The absorption of dietary lipids in the gut is necessary to maintain the metabolic tone of tissues. Inflammation in the gut can cause defects in lipid absorption, which can result in tissue wasting, otherwise known as cachexia. Cachexia is commonly observed in patients with inflammatory bowel disease and cancer patients. The underlying cause of cachexia is unknown, and there are currently no effective therapeutic options available to treat it. Lymphatic drainage in the small intestine (SI) is specialized to promote the transport of dietary lipids into circulation. Lacteals are blunt-ended lymphatic vessels localized to the central axes of villi in …

Adolescent Sleep Health, Mental Health, And Cardiovascular Disease Risk In Adulthood, Prince Nii Ossah Addo

Theses and Dissertations

Background: Insufficient sleep and poor sleep quality are major public health issues among adolescents in the United States (U.S.). Mental health and substance use challenges are also common among adolescents, particularly those with sleep problems. Although exposures in adolescence have been evidenced to significantly impact future health, little is known about how adolescent sleep health, mental health, and substance use influence future cardiovascular disease (CVD) risk. We, therefore, examined the association between sleep health in adolescence and CVD risk in adulthood and assessed whether the association is mediated by depressive symptoms and substance use in adolescents. Further, we explored the …

Child-Caregiver Relational Closeness And Child Mental Health In Nonparental Care Settings, Amanda Stafford Mcrell

Theses and Dissertations

This dissertation examines child-caregiver relational closeness and child mental health within nonparental care systems in Low- and Middle-Income countries (LMICs). Five key factors impacting the well-being of orphaned, separated, and vulnerable children in LMICs are explored using the Positive Outcomes for Orphans (POFO) dataset: child maltreatment, social support, child-caregiver relationships, and nonparental care systems. First, I examined the relationship between maltreatment, social support, and mental well-being. Findings showed that maltreatment was associated with lower mental well-being, where social support (emotional support, tangible support, positive social support) was associated with greater mental well-being, even in the concurrent presence of maltreatment. Second, …

A Study To Identify The Causal Rare Genetic Variants In Primary Open And Closed Angle Glaucoma, Pseudoexfoliation Syndrome, And Associated Glaucoma, Suganya K

Theses and Dissertations

BACKGROUND: Glaucoma is the second most common cause of blindness globally typically diagnosed with a triad of clinical symptoms of increased intraocular pressure (IOP) with associated optic disc, optic nerve head (ONH) changes, and visual field defects. Genetic and environmental factors are some of the strong aetiology factors for glaucoma and identification of these factors has a potential implication in the management of the disease and its outcome. There is a paradigm shift towards understanding the genetics of glaucoma, wherein the variants in the nuclear, mitochondrial genome and other regulatory regions are being identified as contributing risk factors.

METHODOLOGY AND …

A Randomized Controlled Study Of Heart Rate Variability Biofeedback In An Older Adult Sample, Whitney D. Allen

Theses and Dissertations

Heart rate variability biofeedback (HRVB) is a controlled breathing treatment designed to increase the variation in consecutive heartbeats leading to improved regulation of one's autonomic nervous system thereby improving one's ability to self-regulate and maintain homeostasis. Changes in heart rate variability (HRV) are seen in those of increased age and lower HRV is associated with poorer outcomes (e.g., increased mortality, worse emotional functioning, cardiovascular risk factors). As such, older adults are a group that stands to benefit from HRVB principles. The current randomized control trial was designed to understand the impact of HRVB in an older adult population on resting …

1 Studying The Determinants Of Successful Aging: Diet, Lifestyle, And Social Relations In Egypt, Fayrouz Shaltout

Theses and Dissertations

Abstract

Background

The global population is aging rapidly, with projections indicating that by 2050, one in six people will be over the age of 65. In Egypt, the aging population, particularly those aged 60 and above, is expected to grow significantly, posing a growing public health concern. Unhealthful diets (that are associated with overweight and obesity), are one of the main reasons associated with non-communicable diseases (e.g., diabetes and cardiovascular diseases) are major risk factors for poor aging outcomes. Despite this, there is limited research on the specific determinants of successful aging (SA) in Egypt, especially among individuals aged 50 …

Integrating Planetary Health Into Public Health Education For Sustainable Healthcare Practices, Eman Aboualy

Theses and Dissertations

Introduction: Integrating planetary health in public health education became an urgent global call for action since the WHO announced that the climate change and environmental degradation are the most threat facing the humanity in the recent decades (1). According to that, many countries are developing strategies for counteracting and mitigating the impact of climate change and restore the planetary health. These strategies are including policy drafting and preparing their public health professionals to recognize and address the health effects of environmental change, promote practices for sustainable healthcare. Although Egypt is formulating different policies to cope with and respond to the …

The Effect Of China’S Universal Two-Child Policy On Female Employment: A Mixed-Methods Analysis Of Labor Market Outcomes, Sijia Zhao

Theses and Dissertations

This study analyzes the effects of China's Universal Two-Child Policy, enacted in 2016, on women's employment outcomes. The implementation of this policy has highlighted the challenges women face in the labor market, revealing a significant disparity between the policy's effects and expectations, as evidenced by the simultaneous occurrence of low fertility intentions and employment difficulties. This research employs a mixed methodology to systematically evaluate the policy's effects on the quality and stability of women's employment while also investigating the underlying mechanisms of this impact. The research indicates that the Universal Two-Child Policy adversely affects women's employment performance in multiple dimensions. …

Menstrual Poverty In Egypt: Padding The Way To Period Equity, Sara Hesham Nasr

Theses and Dissertations

With approximately 800 million women menstruating daily worldwide, a significant portion of this demographic experiences barriers to accessing sanitary products. In Egypt, despite having around third of the population in reproductive age and menstruating monthly, an economic turmoil in 2017 opted the government to label menstrual products as luxury items and the prices have increased since then.

The current study aimed to investigate menstrual poverty in Egypt, focusing on the economic and social challenges faced by women during menstruation. Key objectives include assessing the financial challenges related to menstruation, exploring existing policies aimed at alleviating these challenges, and proposing evidence-based …

A Qualitative Program Evaluation Of A Community College Mentoring And Advising Initiative For First-Time, Full-Time African American Men, Duane Westley Reid

Theses and Dissertations

Duane W. Reid A QUALATATIVE PROGRAM EVALUATION OF A COMMUNITY COLLEGE MENTORING AND ADVISING INITIATIVE FOR FIRST-TIME, FULL-TIME AFRICAN AMERICAN MEN 2024-2025 Monica Reid Kerrigan, Ed.D. Doctor of Education This study examines the experiences of African American male students within the Operation Achievement initiative at Unique College, a community college in New Jersey with an enrollment of over 8,000 students across its four campuses, located in both urban and suburban settings. The educational challenges faced by African American male students have been widely researched, with many studies highlighting the risk factors that hinder their academic achievement. Variables such as race …

Integrated Agricultural Interventions And Women’S Empowerment\ A Case Study Of “She Feeds The World” – “Aysheen Bekhirha” Program In Egypt, Pakinam Shibl

Theses and Dissertations

“She Feeds the World” program is a program that empowers women in farming communities by integrating them into the agricultural value chain. With increased access to essential resources such as land, seeds, water, and technical training, women are expected to actualize their full potential and generate more income. This paper explores the intersection of societal mobilization and economic development through a case study of the “Aysheen Bekhirha” program. By drawing on primary sources, the researcher aims to provide insights into the program’s multifaceted approach and its impact on economic and social outcomes. The analysis focuses on the significance of women’s …

Evaluating The Performance Of Broccoli (Brassica Oleracea Var. Italica) In The Sandponics System Using Brackish Water With Biochar And Compost, Gabriel Oyebode

Theses and Dissertations

Some of the most pronounced effects of climate change on agricultural output include the depletion of freshwater resources and heightened salinization of arable land, especially in arid and semi-arid regions, adversely affecting crop yields. Many economic vegetable crops including members of the brassica family are sensitive to salt-stress. The use of organic soil amendments such as biochar and compost as complimentary nutrient sources in the sandponics system can improve the performance of crops. The study aimed to evaluate the effect of organic amendment on the growth performance and yield of broccoli and Nile tilapia (Oreochromis niloticus) under brackish …

Daily Pain Experiences And Coping Approaches Among Women In Midlife With Elevated Risk For Cardiovascular Disease, Laura Travers

Theses and Dissertations

Millions of adults experience significant pain each year, costing individuals and our economy millions of dollars in lost productivity and negatively impacting quality of life. Pain is more common among women than men and is a known barrier to women’s physical activity (PA) engagement. Yet, PA helps manage pain and buffer against conditions such as cardiovascular disease (CVD). For women in midlife with CVD risk factors (e.g., hypertension), little is known about daily pain fluctuation and the coping skills employed to manage pain. The current study examined daily pain and pain coping experiences among women ages 40-60 with one or …

Victim/Perpetrator, David D. Moy

Theses and Dissertations

Throughout this text, David Moy will discuss the inner working of his investigation on image overload and materialization. Through tactics of blurring, erasure, and layering he achieves obfuscation in his printed media. In doing so, he questions the compounding nature of image/text that negate themselves in the larger context of time in the digital age.

The Role Of Colleges Of Pharmacy In Student Mental Health Support, Diana J. Patino

Theses and Dissertations

The college journey is not easy, particularly within the pharmacy program— students undergo significant transitions that include meeting new rigor levels and pace in professional coursework, establishing new peers and faculty relationships, and coping with high stress levels (Choi et al., 2019). This qualitative case study will investigate how a pharmacy program and its associated resources relate to student mental health support and how pharmacy students perceive the importance of mental health initiatives in their academic program experience.

Evolution Of Chitinases In Amphibians: A Multi-Faceted Group Of Enzymes With Dual Function In Digestion And At The Forefront Against Fungal Infections, Devashri Narayan

Theses and Dissertations

Chitinases are essential enzymes found in living organisms such as amphibians, and they ensure that amphibians survive in their varied ecosystems. They are crucial in the digestion and immunity of most organisms, including plants and animals. Chitinases’ diversity of functions is a testament to their evolutionary adaptability. The primary function of chitinases is the breakdown of chitin, a complex polymer of saccharides often found in the exoskeleton of insects and the walls of fungi. Amphibians that feed on insects make use of chitinases to hydrolyze chitin into simpler sugars that can be easily absorbed to extract the necessary nutrients from …

The Effects Of Exosomes In Lead And Lps Induced Inflammation In Microglia, Yitzchak Lax

Theses and Dissertations

Exosomes are membrane bound subcellular vesicles formed through membrane budding of a cell and play important roles in cell-cell communication. Studies have demonstrated inflammatory changes in various cell types depending on the etiology of the exosomes such as exosomes from cancer cells or exosomes derived from mesenchymal stem cells. The purpose of this study was to determine the inflammatory consequences of exosomes in microglial cells following exposure to lead, lipopolysaccharides (LPS) and lead+LPS. The cultured mouse microglial cells were treated at 0.01 μM, 0.1 μM and 1 μM of lead,- three environmentally relevant levels and LPS was used at 10 …