Digital Commons Network^™

Synthesis And Biological Evaluation Of Sparsomycin Analogues, Scherer Preston Sanders

Theses and Dissertations

In 1962, Owen, Dietz, and Camiener reported the isolation of a new antitumor antibiotic from the culture filtrate of Streptomyces sparsogenes. The structure of the crystalline antibiotic, named sparsomycin, remained elusive until 1970, when Wiley and MacKellar reported results of spectroscopic and degradation studies which elucidated the structure. In addition to the molecular structure, investigators have examined the mechanism of action, toxicity, and related analogues, striving to establish sparsomycin or a synthetic analogue's usefulness as an effective chemotherapeutic agent.

The initial pharmacological evaluation of sparsomycin revealed it possessed activity against KB human epidermoid carcinoma cells, a variety of gram-negative and …

Alterations In Cerebellar Basket, Stellate And Purkinje Cell Dendritic Development Produced By Zinc Deficiency In The Suckling Rat., Christopher Lee Dvergsten

Theses and Dissertations

Rat pups suckled to severely zinc deficient mothers from birth were killed at 21 days of age. The cerebella were then examined by light and electron microscopy. Dendritic development was analyzed on Golgi-stained sections both qualitatively and quantitatively. Impaired pup growth, alopecia, hunched back posture and decreased femur zinc were seen in zinc deficient pups. Zinc deficiency impaired cerebellar development. The cerebellum was smaller and had fewer granule cells. The molecular layer was thinner and there was a persistence of the external granule cell layer. The normal cytoarchitecture of the cerebellar cortex was maintained in zinc deficient pups; however, basket, …

Audience Participation In A Production Of Canterbury Tales For Children, Jean Pendray Logan

Theses and Dissertations

No abstract provided.

Earth Thermal Storage : Prediction And Verification, Norman R. Cox

Theses and Dissertations

No abstract provided.

Long Ago And Far Away: Distancing In Young Children's Stories., Beth Colleen Anderson

Theses and Dissertations

This study investigated the concept of distancing within the oral stories of 36 children, ages three to five. Distancing was conceptualized, in part, as young children's increasing capacity with age to incorporate fantasy material exceeding the boundaries of their direct experience and to achieve self-other differentiation within the discourse form of stories.The study focused on three research questions: (1) What strategies do young children use to achieve distancing within their oral stories? (2) Do these strategies vary with age? (3) Is the ability to achieve distancing related to other measures of language fluency? The author created a distancing rating scale …

Reductive Denitrogenation Mechanisms Of Aromatic Amines., Vijay Raju Srinivas

Theses and Dissertations

High temperature-high pressure reactions were done with N,N-dimethylaniline and related compounds to study the cleavage of the aromatic and aliphatic C-N bonds, for denitrogenation under coal liquefaction conditions. Reactions were run in a pair of 250-ml Hastelloy 'C' autoclaves and in 12-ml stainless steel autoclaves designed in our laboratory. The range of temperatures studied was 425(DEGREES)C-450(DEGREES)C and that of pressure was 0-1500 psi (initial).The mechanism of the cleavage of both the aromatic C-N bond and the alkyl C-N bond have been postulated. The two sets of conditions studied were; (i) those which excluded any form of sulfur and (ii) those …

Perceptions Of Watergate Among Adolescents, Lade Stuart

Theses and Dissertations

No abstract provided.

The Influence Of Daylength, Temperature And Salinity On The Gametogenic Cycle Of The Banded Killifish, F̲U̲N̲D̲U̲L̲U̲S̲ D̲I̲A̲P̲H̲A̲N̲U̲S̲, David A. Porter

Theses and Dissertations

No abstract provided.

A Study Of Divorced Mormon Women In Salt Lake County: The Extent To Which They Use The Agencies And Institutions Available To Help Meet Personal, Financial, And Employment Needs, Melinda G. Stapley

Theses and Dissertations

The purpose of this study was to (a) describe the characteristics of divorced Mormon women residing in Salt Lake County, (b) determine the extent to which these women were aware of and used government, private, and Mormon church agencies after divorce in helping them solve their problems, and (c) determine the extent these women felt each agency was effective.

Responses from the questionnaire indicated that more than half of these women could be categorized as displaced homemakers. Results showed significant decreases in income before and after divorce. The women in this study had higher than national average occupational levels and …

Measuring The Reading Level Of Lds Materials: A Supplement To The Dale Word List, Linda Stahle

Theses and Dissertations

The purpose of this study was to supplement the Dale word list with a list of terms that are familiar to most members of the Church of Jesus Christ of Latter-day Saints and thus increase the precision of the Dale-Chall readability formula when it is applied to LDS materials. The Dale word list consists of 3,000 words that are familiar to 80 percent of fourth graders. The procedure involved identifying non-Dale words that occur frequently in LDS church publications and testing them on LDS fourth graders in a three-alternative multiple-choice format.

Of the 850 words tested, 249 were identified correctly …

Isolation And Differentiation Of Group B Streptococci From Non-Group B Streptococci On A New Selective And Differential Primary Culture Medium, Bette Rose Wojack

Theses and Dissertations

No abstract provided.

An Analysis Of Selected Undergraduate Student Developmental Programs Designed Especially For Disadvantaged Students, June K. Parisien Randall

Theses and Dissertations

No abstract provided.

The United States House Of Representatives : An Organizational Analysis, Edith L. Lowery

Theses and Dissertations

No abstract provided.

Public Employment Vs. Private Employment : Is The Grass Really Greener On The Other Side?, Richard A. Espeland

Theses and Dissertations

No abstract provided.

A Descriptive Study Of The Administrative Structure And Programs For Women's Athletics In Selected Universities In North And South Dakota, Patricia A. Leno

Theses and Dissertations

No abstract provided.

Enterotoxin Production By S̲T̲A̲P̲H̲Y̲L̲O̲C̲O̲C̲C̲U̲S̲ A̲U̲R̲E̲U̲S̲ Isolates Obtained From Nursing Homes, Gregory D. Greek

Theses and Dissertations

No abstract provided.

An Experimental Study For Improving Halftone Print Quality Using The Diffusion Transfer Process, Gregory W. Carnehl

Theses and Dissertations

No abstract provided.

An Analysis Of The Effect Of Immediate Corrective Feedback Administered As A Study Aid To Undergraduate Medical Technology Students, Constance Anne Bak

Theses and Dissertations

Twenty-six undergraduate medical technology students at Virginia Commonwealth University were provided with a Hemestasis Study Guide to use during this unit and in preparing for an exam in this area. The study guide contained fifty objective-related questions in multiple-choice format. Answers were printed in latent image and included positive reinforcement for correct selections and remediation for incorrect ones. Thus the student received immediate feedback concerning his response to each question.

An examination grade continuum was plotted for this class utilizing all exam grades in the Hematology course. A similar continuum was plotted for each of the three previous classes. (These …

Genetic Studies Of Questionnaire Data From A Residential School For The Deaf, Frederick Robert Bieber

Theses and Dissertations

A self-administered thirteen page Hearing Loss Questionnaire (HLQ) was designed in order to systematically collect medical and family history data on deaf children and their families. Data were collected from over 400 families with one or more children enrolled in September 1979 at the Maryland School for the Deaf (MSD). Almost 70% of the parents provided pedigree and family history information by completing the detailed HLQ. Computer analyses of the collected data allowed a thorough examination of almost 200 medical and family history variables, providing useful reference data on the MSD probands. Parental responses to a four-step rating scale of …

Solubilization And Partial Characterization Of An Activity Regulating Complement Activation From Membranes Of Raji And Tonsil Cells, Patricia L. Carlson

Theses and Dissertations

Complement is one of the major innate nonspecific mechanisms for host defense in serum. More than a dozen proteins have been isolated from serum which have a function in either the activation or regulation of complement action. Complement is similar to the coagulation sequence in that it comprises a number of precursor proenzymes in plasma that are sequentially cleaved to generate biologically and enzymatically active proteins.

Anticipating The Future: Minot State College In The Decade Of The 80'S., Ellen Jane Kegel

Theses and Dissertations

This study concerns the efforts of Minot State College, one of North Dakota's state-supported institutions of higher education, to conduct long-range planning activities, to generate its institutional plan for the 80's, and to define its mission in response to a mandate from the state's Board of Higher Education. To facilitate these efforts the college employed the author as planning coordinator for the project from October 1979 through June 1980.One of the challenges of the study was to use well the planning model specified by the Board. A Futures Creating Paradigm: A Guide to Long-range Planning from the Future for the …

Relationships Between Sex-Role And Selected Self-Concept Dimensions For Male And Female College Students., Randolph Charles Moredock

Theses and Dissertations

Problem. The purpose of the study was to examine the relationship between sex-role and self-concept for males and females, and to translate the findings into statements about male and female self-concept patterns. The null hypotheses tested were: (1)No relationship exists between sex-role and self-concept for males. (2)No relationship exists between sex-role and self-concept for females. (3)When males and females are compared across sex, sex-role, and sex by sex-role, no differences in self-concept exist.Procedure. The subjects, 90 males and 126 females, were undergraduate volunteers at the University of North Dakota. Each subject completed the Tennessee Self Concept Scale (TSCS) and Bem …

Vachel Lindsay: The Dispersed And Prepared Audience., Kenneth Peder Peeders

Theses and Dissertations

Vachel Lindsay travelled thousands of miles, subjected himself to a grueling schedule of public appearances and stressed the oral presentation of his poetry over and above simple publication alone. In so doing, he set himself apart from others in the New Poetry movement which began during the second decade of this century. This study documents Lindsay's uniqueness.It does so by exploring, in chapter one, his search for an audience, first, through publication in magazines and through the publication of a volume of his verse, and, second, through oral presentation. It establishes Lindsay's early interest in the voice-to-ear approach and presents …

Length Of Time For College Graduates To Obtain Employment And Selected Job Related Variables., Jole Ann Williams

Theses and Dissertations

The purpose of this study was to determine if there is a significant relationship between the length of time it takes Trinity University graduates to become employed and the identified job related variables and combinations of variables. The job related sets of variables are: (1)background variables, (2)variables related to academic major and grade point average, (3)variables related to employment seeking behaviors influencing job attainment, (4)variables related to ethnic background and socio-economic status, and (5)variables related to geographic and organization size preference.The group surveyed in this study was the Trinity University graduates who had received bachelor's degrees in December 1978, May …

Study Of The Optical Constants Of Bismuth Tellurium Sulfide., Vinod Kumar Nangia

Theses and Dissertations

Experimental measurements of the optical reflectance of bismuth tellurium sulfide, Bi(,2)(Te(,1-x)S(,x))(,3); x = 0.48 were carried out both at normal and oblique incidence angles over a range of wavelengths. Bismuth tellurium sulfide is a uniaxial crystal that grows as a layered structure in sets of five atomic layers called quintuple layers. These layers are perpendicular to the optic axis of the crystal. Due to week Van der Waals bonds between the adjacent quintuple layers, the crystal cleaves easily along these layers and presents atomically smooth surfaces for reflectance studies. The measured reflectance spectra were analyzed by two different methods to …

An Analysis Of Alternative Educational Delivery Systems In Northwestern Minnesota., Adeline Katie Jaeger

Theses and Dissertations

The study purpose was to learn the perceived general desirability and also the perceived specific feasibility of nineteen alternative educational delivery ideas, many of which required inter-district cooperation. The population included individuals who had formally served the fifty-two school districts of northwestern Minnesota as representatives for areawide educational planning, or as superintendents of schools, or as both superintendents and representatives. The instrument used to gather data was based upon delivery ideas which resulted from long-range educational planning activities. These activities had been mandated by the Minnesota Legislature in 1976.Five research questions considered (1) role of the respondent during planning, (2) …

Effectiveness Of The North Dakota Highway Patrol Personnel Selection Standards, Susanna Wittmier

Theses and Dissertations

No abstract provided.

The Electrochemistry Of Amines And Carbonium Ions In Room Temperature Aluminum Chloride : N-Butylpyridinium Chloride Molten Salts, Garth D. Luer

Theses and Dissertations

No abstract provided.

Biogeochemical Relationships Of Sulfur-Oxidizing Soil Bacteria Adjacent To Lignite-Fired Power Plants In Western North Dakota, Wayne L. Moe

Theses and Dissertations

No abstract provided.

Factors Influencing Soil Respiration On Native Mixed-Grass Prairies And Reclaimed Mine Sites, David A. Bolt

Theses and Dissertations

No abstract provided.