Digital Commons Network^™

Student Perceptions Of The Effectiveness Of Collegiate Recovery Programs And Collegiate Recovery Communities, Michael Anthony Herold

Theses and Dissertations

Research on the objective effectiveness of Collegiate Recovery Programs and Collegiate Recovery Communities (CRPs / CRCs) has shown success in maintaining recovery and improving academic outcomes for college students in recovery, but research on the experiences of this population is starting to emerge. This study used a mixed-method design to investigate the perceptions of members of CRPs / CRCs regarding the impact of participation on their recovery from substance abuse and their overall quality of life. Thirty-one participants completed the Drug Avoidance Self-Efficacy Scale (DASES) and the Quality of Life Index – Generic Version iii (QLI). Paired samples t-tests were …

Examining Factors Among People With Opioid Use Disorder And Comorbid Mental Health Disorders, Tori Denae Livingston

Theses and Dissertations

Opioid use disorder (OUD) affects over two million Americans, and over 42,000 Americans perished of opioid overdoses in 2016 (Volkow et al., 2019). During the initial years of the opioid crisis, overdose deaths were primarily attributed to prescription analgesics, heroin, and synthetic opioids. However, it was illicit prescription opioid painkiller use that ranked highest in terms of fatalities (Volkow et al., 2019). The increasing prevalence of opioid use among individuals with mental health disorders is in stark contrast to the ongoing opioid crisis (Prince, 2019). Additionally, there is evidence that individuals undergoing substance use treatment and concurrently suffering from a …

Professional Development, Digital Platforms, And Middle School Education During Covid-19, Cynthia Susan Castro

Theses and Dissertations

The COVID-19 outbreak shifted towards online learning, requiring educators and administrators to adapt to new digital platforms and technologies quickly. The purpose of this quantitative study is to examine whether there is a significant difference in the frequency of use of digital platforms among middle schools. Secondly, it explores the relationship between teachers' attendance at professional development sessions and their integration of Nearpod lessons during the pandemic. Lastly, it investigates the relationship between the time campus principals invested in technology-related professional development and teachers' adoption of digital platforms at their respective campuses. Surveys and administrative records were …

Chemical Investigation Of Dichloromethane Extract Of Aloe Vera Peels: An Agricultural Waste, Nazmul Huda

Theses and Dissertations

Aloe barbadensis Miller, commonly called Aloe Vera, is a widely popular succulent plant species cultivated across subtropical regions worldwide from India to the Tex-Mex border. Besides its historical uses, Aloe juice has garnered attention as a potential remedy for various ailments, particularly in treating various skin conditions and facilitating wound recovery, including obesity, diabetes, hepatitis, Crohn's disease, and ulcerative colitis. Regrettably, the agricultural practice following sap extraction involves discarding Aloe vera peels, constituting agricultural waste. As part of our continuous research on extraction, isolation, separation, and spectral characterization of value-added chemicals present in waste botanicals herein, …

Age-Related Oligodendrocyte Lineage And Learning Abnormalities Driven By Nf1 Mutation In Mice, Saul Lopez

Theses and Dissertations

Neurofibromatosis Type 1 (NF1) is an autosomal dominant disease caused by mutations in the NF1 gene, on chromosome 17. NF1 patients suffer from a number of neurological issues including learning deficits and increased risk of age-related dementia. Additionally, NF1 patients present with multiple white matter and myelin abnormalities. Whether and how myelin abnormalities impact learning in NF1 is not known; therefore, we aimed to gain insights on potential links between Nf1 mutation and learning issues Unpublished data indicate that NF1 female-but not male- mice with Nf1+/- germline mutation show defects in a myelin-regulated learning/memory test (the complex wheel; CW) at …

Federated Active Learning For Network Intrusion Detection, Matthew D. R. Sauer

Theses and Dissertations

This thesis addresses challenges with detecting attacks on computer networks within a Federated Learning (FL) framework, when labeled instances are few. We explore the integration of active learning (AL) and semi-supervised learning (SSL). AL efficiently uses data that would otherwise be wasted or require substantial time for labeling. SSL provides capacity to train models that have a limited amount of labeled data, by utilizing additional unlabeled data that is available. We show how FL combined with AL or SSL can realize a detection system that adapts and trains quickly to new networks, reducing the total amount of data labeling needed. …

The Association Between Immigration And Recidivism Among Juveniles: Exploring The Effects Of Acculturation, Moral Disengagement, Employment And Community Involvement., Juanita Mirekuaa Sefa

Theses and Dissertations

The topic of immigration remains a highly debated issue, particularly in light of rising worldwide migration and its potential impacts on crime rates. This study aims to investigate the association between immigration and recidivism among juveniles and the mediating effects of acculturation, moral disengagement, employment, and involvement in community activities on recidivism. The data for this study is drawn from the Pathways to Desistance study of serious adolescent offenders. It follows approximately 1354 serious adolescent offenders, of which 210 are second-generation and 83 are first-generation immigrants. Recidivism was measured using a period of twelve months. Findings indicated that second-generation immigrants …

The Lived Experiences Of Esl Nontraditional Rrts While Preparing To Challenge The National Board For Respiratory Care Clinical Simulation Exam, Jose A. Lammoglia

Theses and Dissertations

This applied dissertation was designed to provide information to respiratory therapy graduates from two-year associate in science programs, faculty, and administrators about

the cognitive and noncognitive strategies employed by graduates to prepare and pass the CSE. To date, no available information on the role played by the lived experiences of RT graduates while preparing to challenge the CSE. The researcher developed a questionnaire to conduct a qualitative phenomenological descriptive lived experience survey of ESL Hispanic nontraditional graduates from associate of science programs in South Florida who took the NBRC national board examinations between January 2015 and March 2022.

An analysis …

Recommendations For The Mental Health Treatment Of Human Trafficking Survivors, Christina M. Tsoi

Theses and Dissertations

Human trafficking is a worldwide problem that places those trafficked at very high risk for multiple adverse outcomes, including mental illness. Although research on human trafficking has become abundant in other academic disciplines (e.g., sociology, public health, criminology, social work), psychology research specific to the mental health treatment of survivors remains limited. Objective: The purpose of this study was to gather recommendations from mental health professionals for the mental health treatment of trafficking survivors. Method: This paper reviewed extant literature regarding human trafficking and current mental health treatment provided to survivors. Semi-structured interviews were conducted with 21 mental health professionals …

Rage In Chronic Pulmonary Inflammation And Obstetric Complications, Katrina Lynn Curtis

Theses and Dissertations

The receptor for advanced glycation end-products (RAGE) is a transmembrane cell surface protein of the immunoglobulin superfamily that acts as part of both the innate and adaptive immune system. RAGE is highly expressed in lung tissue and is therefore of interest in the pulmonary immune response. Specifically, RAGE mediates several cell-signaling responses such as inflammation and apoptosis. This work sought to elucidate the role of RAGE in the setting of chronic pulmonary irritation such as that found in long-term exposure to secondhand smoke (SHS). This irritation has several shared characteristics with lung diseases such as chronic obstructive pulmonary disease (COPD) …

Reframing Writing Teachers As Writers: Using Online Messages As Teaching Tools During Crisis And Beyond, Emily Capan

Theses and Dissertations

College writing teachers compose and write professionally often in our positions, but how often are we recognized as writers and not only as teachers of writers? During the sudden shift to emergency online learning during the COVID-19-interupted Spring 2020 semester, online communication became the primary, if not the only, way that college writing instructors were able to communicate with undergraduate students. Relying on surveys, interviews, and written artifacts, this dissertation investigates how college writing instructors at one Midwestern university learned to compose crisis communication messages to students in 2020–and what we have continued to learn and practice as online communicators …

Prosodic Pitch And Intensity In Autistic Individuals, Cassidy Gooch

Theses and Dissertations

This study is an examination of how prosodic pitch and intensity compare in autistic individuals and neurotypical individuals. Ten-minute recordings of casual conversation were taken and analyzed. Participants included 11 autistic individuals and 11 neurotypical individuals with six males and five females in each group. The Autism Diagnostic Observation Schedule, 2nd Edition (ADOS-2; Lord et al., 2012) prosody rating scale was used to collect a perceptual evaluation of each participan's prosody, and Praat acoustic analysis software was used to collect measures of pitch and intensity over the 10-minute period to investigate how speech characteristics change with conversation partner familiarity. Results …

Stability, Longevity, And Regulatory Bionetworks, Christian N. K. Anderson

Theses and Dissertations

Genome-wide studies of diseases and chronic conditions frequently fail to uncover marked or consistent differences in RNA or protein concentrations. However, the developing field of kinetic proteomics has made promising discoveries in differences in the turnover rate of these same proteins, even when concentrations were not necessarily different. The situation can theoretically be modeled mathematically using bifurcation equations, but uncovering the proper form of these is difficult. To this end, we developed TWIG, a method for characterizing bifurcations that leverages information geometry to identify drivers of complex systems. Using this, we characterized the bifurcation and stability properties of all 132 …

Seeking Connection By Forsaking Self: Associations Of Autonomy And Relatedness With Self-Silencing And Emotional Fusion, Amber A. Price

Theses and Dissertations

Humans innately feel a desire for connection, but in its pursuit, some may inadvertently thwart the very connection they seek. One way this may happen is through forsaking a sense of autonomy in favor of relatedness using behaviors such as self- silencing (stifling the self to preserve a relationship) and emotional fusion (relying on validation from others). To better understand how these four variables—autonomy, relatedness, self-silencing and emotional fusion—function together, I used latent profile analysis to identify classes among US adults in long-term relationships (n = 1065). Separate classes were identified for men and women. I then used the Bolck-Croon-Hagenaars …

Assessing Organizational Policy: Preferred Practices For Regulating Vaping In The Work Environment, Ayesha T. Kirk

Theses and Dissertations

Employee vaping negatively affects organizations in terms of costs, productivity, employee health, and workplace safety. The purpose of this qualitative dissertation study was to assess organizational policies to determine preferred practices to regulate vaping in the work environment. Open-ended questionnaires with 18 human resources administrators, combined with a literature review, yielded data on best practices for organizational policies regulating vaping in the work environment.

The data collected in this qualitative dissertation study were extracted from a structured survey questionnaire comprising 16 questions about vaping and tobacco usage in the workplace. The findings demonstrated that vaping and the use of tobacco …

Mechanisms, Evolution, And Rapid Diagnosis Of Carbapenem Resistance, Taalin Shale Hoj

Theses and Dissertations

An estimated 70% of bacterial infections in the United States are resistant to first-line antibiotics. Of these, among the most difficult to treat are highly resistant to carbapenems, an antibiotic class used as a last resort. Septicemia, particularly when caused by a carbapenem-resistant organism, is among the most challenging clinical scenarios to treat, with an overall mortality rate of carbapenem-resistant septicemias 63.8%. Encouragingly, if effective antimicrobial treatment begins within 1-3 hours of septic shock onset, patient survival rates are around 80%. The first section of this work describes a real-time PCR-based assay that when coupled with existing bacteria-blood separation technology, …

Elucidating The Architecture Of The Tclijn Complex That Converts Cysteine To Thiazoles In The Biosynthesis Of Micrococcin, Diana G. Calvopina Chavez

Theses and Dissertations

Thiopeptides are a family of antimicrobial peptides that are characterized for having sulfur-containing heterocycles, and for being highly post-translationally modified. Numerous thiopeptides have been identified; almost all of which inhibit protein synthesis in gram-positive bacteria. These intrinsic antimicrobial properties make thiopeptides promising candidates for the development of new antibiotics. The antimicrobial peptide micrococcin is a thiopeptide that is synthesized by the ribosome and undergoes several post-translational modifications (PTMs). Micrococcin is formed from a precursor peptide, TclE. TclE comprises an N-terminal leader (35-AA) that is crucial for recognition of the PTM machinery, alongside a C-terminal core sequence (14-AA) that undergoes multiple …

The Experiences Of Microaggressions Among Latiné Health Service Graduate Students And The Supervisory Relationship, Mackenzie Callahan

Theses and Dissertations

Although data has shown that psychology graduate programs are actively recruiting more Students of Color every year, there is not as much evidence that these programs are able to adequately support these students once they arrive. The purpose of the current study is to examine how Latiné graduate students’ experiences of microaggressions from their supervisor affects their supervisory relationship, as well as their perceptions of their graduate program climate. I collected survey data from 80 Latiné psychology graduate students from across the United States and conducted small focus groups with five participants. I found that exposure to microaggressions within supervision …

Analysis Of Benefits Of Udot's Expanded Incident Management Team Program, Joel Clegg Hyer

Theses and Dissertations

In 2019, the Utah Department of Transportation (UDOT) funded a research study evaluating the performance measures of UDOT's expanded Incident Management Team (IMT) program. The number of IMTs patrolling Utah roadways increased from 13 to 25 between 2018 and 2020. Crash data were collected from the Utah Highway Patrol's Computer Aided Dispatch database and from the UDOT TransSuite database to compare IMT performance measures between the two years and to evaluate the benefits of the expanded IMT program. However, these data were compromised due to the effects of the COVID-19 pandemic. This study collected data for 2022 using the same …

Manipulating And Assaying Chromatin Architecture Around Enhancer Elements In Vivo, John Lawrence Carter

Theses and Dissertations

There are about 20,000 genes in the human genome. The lowly nematode worm, C. elegans, has about the same number of genes. How could two organisms that are so different arise from a similar number of genes? The answer is epigenetics, or the factors that help control when and where genes are expressed. There are many layers that comprise the epigenetic control of genes. One of which is the structure or architecture of chromatin. Chromatin is a complex of DNA and proteins. Histone proteins with DNA wrapped around them form the fundamental component of chromatin, the nucleosome. Chromatin exists in …

Monitoring Brain Region-Specific Control Of Protein Turnover And Concentration Using Proteomics, Rebecca Suzanne Burlett

Theses and Dissertations

Regulation of metabolism is vital to health and lies at the core of many different diseases. The breakdown of metabolisms' regulation within the brain can lead to neurological disease like Alzheimer's Disease (AD). AD is known to affect brain regions responsible for memory and memory processing like the hippocampus and entorhinal cortex. The regulation of these regions' protein quality, synthesis, and degradation deviate from 'normal' or 'healthy' levels when AD is happening. It is known there is a breakdown of regulation in those regions; however, little is known about the specifics of regulation in healthy brains regions or how it …

Dispensing With Humans In Human-Computer Interaction Research, Courtni L. Byun

Theses and Dissertations

Machine Learning models have become more advanced than could have been supposed even a few years ago, often surpassing human performance on many tasks. Large language models (LLM) can produce text indistinguishable from human-produced text. This begs the question, how necessary are humans - even for tasks where humans appear indispensable? Qualitative Analysis (QA) is integral to human-computer interaction research, requiring both human-produced data and human analysis of that data to illuminate human opinions about and experiences with technology. We use GPT-3 and ChatGPT to replace human analysis and then to dispense with human-produced text altogether. We find GPT-3 is …

Inconsistent Correlation And Momenta: A New Approach To Portfolio Allocation, David Kercher

Theses and Dissertations

Correlated stocks should, in equilibrium, have correlated momenta, but in practice momenta do not always correlate. We use short-term inconsistencies between correlations and momenta to predict price corrections, produce more meaningful investment indicators, and improve upon accepted investing strategies. In particular, our approaches integrate inconsistencies within an entire security class rather than relying only on individual or pairwise security data. We use this theory to improve upon not only the standard momentum portfolio but also Pair Trading and Momentum Reversion methods. This results in three strategies for portfolio allocation that outperforms overlying indices and market benchmarks by 5%-10% in annual …

Cell Of Origin Identification Using Methylation Signatures From Seminal Cell-Free Dna And Heterogenous Cellular Mixtures, Ryan Barney

Theses and Dissertations

Infertility is an issue for approximately 12% of couples attempting to have a child. Of this group, 50% of the cases are due to male factor infertility. There are many reasons for decreased fecundity in men, but there remains 10% to 15% of infertile men that are diagnosed with the most severe form of infertility, non-obstructive azoospermia (NOA). A diagnosis of NOA implies the lack of sperm cells in the ejaculate with no physiological reason. The current diagnostic test and treatment consist of microscopic examination of seminal fluid and a biopsy to extract any viable sperm from the testis. This …

The Influence Of The “Hayah Karima” Initiative On The Standard Of Living Of Egyptian Citizens: Evidence From The Menofia Governorate, Merihan Sharara

Theses and Dissertations

Social protection programs have been used in several developing countries in order to aid in their development efforts. In Egypt, “Hayah Karima”, an initiative which represents a developmental initiative endorsed by Egypt’s President Al-Sisi, aims to minimize the developmental gaps among citizens in terms of standards of living. “Hayah Karima” is based on governmental finance in partnership with the private sector. This paper covers this initiative and its different aspects as well as their possible impact on the standards of living for citizens in El- Menofia Governorate. The paper also includes 71 surveys conducted with different partners and beneficiaries of …

The Social & Economic Impact Of Two-Year And Community Colleges On African Americans In The Central Mississippi Region, Bryan Winfred Massey Sr

Theses and Dissertations

The purpose of this study is to examine the social and economic impact of two-year and community colleges on minorities particularly African Americans who are earning a certificate, transfer credits to a four-year institution, or an Associate of Arts or Science Degree. The proposed research is a qualitative case study investigating the social and economic impact of two-year junior institutions that award certificates of learning and community colleges that award Associated Degrees to African Americans in the Southern Mississippi Delta Region. The primary focus of this case study will be the alumni for community colleges in the central part of …

Dynamic Regulation Of Store-Operated Calcium Entry By Protein S-Acylation, Goutham Kodakandla

Theses and Dissertations

Calcium plays a pivotal role in many physiological functions in cells. Cytosolic calcium levels are finely tuned by calcium ion channels, pumps, and intracellular organelles. Store-operated calcium entry (SOCE) is when depletion of endoplasmic reticulum (ER) calcium stores activates a calcium sensor known as stromal interaction molecule 1 (STIM1). Activation of STIM1 leads to a conformational change from a compact state to an extended state. This extended state of STIM1 allows it to bind to a calcium channel in the plasma membrane (PM) known as Orai1. The binding of Orai1 and STIM1 leads to opening of Orai1 channels and calcium …

Developing 3d Printed Integrated Microfluidic Devices For Microchip Electrophoresis Separation Of Preterm Birth Biomarkers, Joule E. Esene

Theses and Dissertations

Preterm birth is a global health challenge and the leading cause of neonatal mortality. Each year, about 15 million babies are born preterm globally. Traditional tools that have been exploited for the detection of preterm birth biomarkers are expensive, time consuming, or lack multiplexing capabilities. The work described in this dissertation highlights techniques developed to detect preterm birth biomarkers rapidly and accurately in the effort to mitigate preterm birth risk. In this dissertation, I first demonstrated the use of stereolithography digital light processing-based 3D printing and microfluidics for the development of microfluidic devices that had microvalves for fluid control. I …

A Definition Of Reliable Water Supply For Public Water Systems, Easton Hopkins

Theses and Dissertations

"Reliable water supply" does not have a universal definition in Utah, or the Western United States, where water resources are limited and such a definition would be especially useful. Utah's three water agencies and 500 public water systems have no consistent method to define, evaluate, and report it, potentially leading to an inability to meet regulatory water demands. We propose a unified definition of reliable water supply for Utah's public water suppliers that can also be used elsewhere. The qualitative definition we propose is necessary to precede quantitative evaluations, set policy, and provide consistency to water resources management in Utah. …

Is Coping Enough? Examining Coping And Burnout Among Educators In A Pandemic, Caitlyn Jezowit

Theses and Dissertations

Coronavirus-19 (COVID-19) intensified workplace stressors for educators worldwide. A teacher’s job demands and resources contribute to workplace stress, which can lead to burnout and can have negative effects on the school environment, student outcomes, and turnover intentions. Coping strategies and one’s coping self-efficacy are critical to stress management. This study examined how teachers perceive their coping strategies and abilities, and their job characteristics during the pandemic. The current study also explored the associations among the perceived impact of COVID-19, job demands and resources, coping, burnout symptoms, and turnover intentions. In this study, 198 teachers completed a survey about their perceptions …