Digital Commons Network^™

Effects Of Mindfulness Training On Prosocial Responses In Intergroup Relations: A Pilot Randomized Controlled Trial, Denise Yiran Zheng

Theses and Dissertations

Based on social identity theory and intergroup emotions theory, individuals feel for and act toward others based on their group-based social identities. Recent research shows that mindfulness can enhance prosocial responses toward others across group divides. The current research examined the effects of mindfulness training on prosocial behavior in intergroup relations where such behavior is difficult (e.g., with marginalized or devalued social groups). The study also examined potential mechanisms, namely state empathic concern and appraisal, that may explain how mindfulness increases prosocial behavior toward outgroups. This study compared the effects of a 2-week mindfulness training to a matched coping training …

Outcomes Of Anterior Crossbite Correction On Alveolar Bone Morphology In Patients With Cleft Lip And Palate, Katherine J. Hayes

Theses and Dissertations

Objective: To determine if patients with cleft lip and/or cleft palate (CLP) with dental correction of the anterior crossbite during growth display differences in alveolar bone thickness around the maxillary central incisors compared to patients without crossbite correction.

Methods: This retrospective study evaluated post-treatment cone beam computed tomography (CBCT) images of growing patients with CLP with anterior crossbites who underwent Phase I orthodontic treatment (n=32). CBCTs were sorted by whether the crossbite was corrected (n=16) or not corrected (n=16) during Phase I. Alveolar bone thickness was measured on the buccal and palatal aspects of the central incisors at 3 mm, …

The Effects Of Various Nanoplastics On The Inflammatory Response In Primary Alveolar Epithelial Cells, Eunice J. Pak

Theses and Dissertations

As plastic pollution begins to multiply in the environment and the workplace, gradual degradation of these plastics creates an unseen threat to biological health: nanoplastics. These nanoplastics are common in day-to-day life, and have been found in various internal organs of the human body. The biological and health effects of these nanoplastics are still widely unknown, and only recently has research focused on the impacts of these particles on human health at the cellular level.

In this thesis, poly(methyl methacrylate) and three forms of polystyrene (carboxyl-modified, amine-modified, and neutral surface charge) have been tested on submerged primary C57BL/6 mouse alveolar …

The Effect Of Experienced Compassion At Work On Nursing Home Certified Nursing Assistants' Well-Being And Turnover Intentions, Kristin M. Macdonald

Theses and Dissertations

Statement of problem and objectives: Could experienced compassion at work alleviate nursing home certified nursing assistant (CNA) burnout? This study investigates whether experienced compassion at work predicts higher well-being (meaningfulness of work, psychological vitality, and resilience) for CNAs, and if well-being predicts lower turnover intentions.

Procedure followed: This is a prospective, observational, survey-based study with three timepoint data collection. Convenience sampling of Kansas and Virginia NHs was conducted (n=13). All CNAs working at the NHs were study eligible. CNAs received gift cards with laddered incentives for ongoing participation. There was in-person administration of a CNA survey at each timepoint. …

Planning Growth Management; The Rapid Urbanization Of Loudoun County, Virginia, Shaianna Trump

Theses and Dissertations

As the population grows, planners and politicians must decide how to direct growth. This thesis analyzes how growth management can control land use and development using Loudoun County, Virginia, as a case study. By looking at how Loudoun County has implemented growth management policies, a case can be made for why governments should look to growth management to manage growth pressures. This thesis looks at the past and present growth management policies in Loudoun County and analyzes the County’s 2019 Comprehensive Plan.

How To Forget, Jesse D. Hoyle

Theses and Dissertations

How To Forget was born from a need to give tangible form to the psychic residue left behind by a life lived. Through the use of silk-screening of red clay mud onto ink-jet photographs, archival textiles, and site-specific installations, I attempt to tie and/or divorce myself from my own and my family's extended history and examine the function of memory within the dynamics of the archive. How To Forget takes a non-linear, non-chronological approach to this examination, compressing decades of time and space through the manipulation of the archive and my own self-portraiture, designed specifically to deny myself from its …

The Effect Of 17Β Estradiol On Local Production Of Active Vitamin D3 Metabolites In Laryngeal Squamous Cell Carcinoma, Tillat Batool

Theses and Dissertations

Laryngeal squamous cell carcinoma (LSCC) has garnered attention as a sex-hormone-dependent cancer with notable responsiveness to 17β-estradiol (E₂), in which it’s tumorigenesis can be mediated through estrogen receptors (ER). The ESR1 gene encodes for the classical full-length ERα66, as well as splice variants ERα36 and ERα46. Previous studies have shown that an active vitamin D₃metabolite, 24R,25(OH)₂D_3. has pro-tumorigenic or anti-tumorigenic responses in LSCC cells with different ER profiles, and that the tumor cells have the capability of localized production of vitamin D metabolites at the cellular level when treated with 25(OH)D₃-d6 …

Obstacles To And Facilitators Of Services In Child Welfare In The Context Of The Family First Prevention Services Act, Juliet Wu

Theses and Dissertations

The child welfare system has generally focused on child wellbeing and protection in the context of abuse or neglect allegation, supporting caregivers with child rearing, and finding a stable, permanent home for children. Because children and caregivers involved with the child welfare system typically have complex needs, public departments of social services often collaborate with other entities to provide services to families. However, connecting families to services has often been difficult, with many barriers along the way that prevent families from receiving the services they need. The enactment of the Family First Prevention Services Act (FFPSA) in 2018 aimed to …

Re-Programming Transcription Factor Function For Neuroscience Research Of Addiction: Investigating The Role Of Zinc Finger Proteins In Driving Cocaine Reinforcement In Mice, Joseph A. Picone

Theses and Dissertations

Administration of addictive drugs like cocaine or morphine initiates aberrant gene transcription within brain reward circuitry neurons, which contributes to the lasting behavioral maladaptations that define addiction. The drug-induced expression and function of key brain transcription factors (TFs) is one major mechanism through which these drugs are able to regulate transcription, and as a consequence, lasting damaging drug-related behaviors including compulsive drug use. The goal of this dissertation is to more fully understand the molecular mechanistic drug-specific actions of TFs within the rodent nucleus accumbens (NAc). The findings from these studies could serve as the basis to identify novel candidate …

The Cultural Adaptation Of An Eating Disorders Assessment Tool For South Asian American Women, Neha J. Goel

Theses and Dissertations

South Asians (SAs) are less likely to be screened, referred, and treated for eating disorders (EDs), although they experience these serious health conditions at rates similar to those of their White counterparts. Available ED assessment tools do not adequately capture cultural nuances in the presentation of eating psychopathology in SAs. Thus, the current study culturally adapted the Eating Disorder Examination-Questionnaire (EDE-Q) to enhance its validity, applicability, and cultural relevance for SA women living in the US. During the cultural adaptation phase, the principal investigator consulted with participant experts (N=24) and research experts (n=4) to create the …

A Multilevel, Mixed Methods Examination Of Food Insecurity, Housing Instability, And Cardiovascular Health, Sarah Collins

Theses and Dissertations

BACKGROUND

Housing instability and food access are both robust risk factors for cardiovascular disease (CVD), which claims more lives annually in the U.S. than cancer and chronic lung disease combined. We hypothesized that experiencing both housing instability and food insecurity would have an additive effect on CVD risk, resulting in elevated blood pressure (BP) and perceived stress among young adults (YA).

METHODS

This research examined the relationships between food insecurity, housing instability, stress, and cardiovascular disease risk through three aims. First, multivariate linear regression was used to assess associations among YA, focusing on eviction, food insecurity, and blood pressure. Second, …

Transgender Perceptions Of Breast Health Care And Utilization Of Preventative Breast Imaging Services, Cherish Parham

Theses and Dissertations

Little information exists on transgender patient perceptions of breast imaging care at mammography facilities. The purpose of this descriptive phenomenological study was to understand the lived experiences of transgender patients at mammography facilities, their knowledge of breast care, and how these experiences have shaped their perceptions of the breast imaging community and attitude toward breast cancer screening. By applying the revised the Gelberg-Andersen Behavioral Model for Vulnerable Populations, this study addressed factors specific to the transgender population that may affect their healthcare utilization and how that impacts health outcomes. Researchers collected data from transgender/non-binary individuals in the Richmond, Virginia region …

Efficient Connectivity Management And Path Planning For Iot And Uav Networks, Amirahmad Chapnevis

Theses and Dissertations

This dissertation explores how to better manage resources in mobile networks, especially for enhancing the performance of Unmanned Aerial Vehicles (UAV)-supported IoT networks. We explored ways to set up a flexible communication architecture that can handle large IoT deployments by making good use of mobile core network resources like bearers and data paths. We developed strategies that meet the needs of IoT networks and enhance network performance. We also developed and tested a system that combines traffic from several mobile devices that use the same user identity and network resources within the core mobile network. We used everyday smartphones, SIM …

Analyzing The Role Of Slc25a32 In Hepatocellular Carcinoma, Mimansha Shah

Theses and Dissertations

Hepatocellular carcinoma (HCC) is the most common primary liver cancer and a leading cause of cancer-related deaths worldwide. Despite advances in understanding its molecular pathogenesis, treatment options for HCC remain limited, highlighting the need for identifying novel therapeutic targets. This study investigates the role of SLC25A32, a mitochondrial transporter gene located on chromosome 8q22.3, in HCC progression. SLC25A32 is involved in the transport of tetrahydrofolate (THF) and flavin adenine dinucleotide (FAD) into mitochondria, playing a crucial role in one-carbon metabolism and redox balance. Using CRISPR/Cas9 technology, we generated potential SLC25A32 knockout clones in the HCC cell line Huh-7. Quantitative PCR …

Shape Inverse Prediction Of Magnetic Field-Actuated Soft Robots By Neural Network Machine Learning, Lineth J. Perez Monsalve

Theses and Dissertations

Soft robotics has drawn tremendous interest in recent years because the compliance and motion of soft robotics enable biocompatibility and versatility for many applications, such as human-machine interaction, wearable and assistive devices, and health monitoring. This study introduces a novel predictive modeling approach using neural networks for shape control of magnetic soft robots. The robots are made of silicone materials embedded with hard magnetic particles, which respond to the external magnetic field provided by a ring-type of permanent magnet. These robots, free from physical connections to external devices, i.e., non-tethered actuation, hold significant potential for applications in healthcare, such as …

Role Of Human Intermediate Form Prl Receptor I-Tail In The Pathogenesis Of Breast Cancer, Shanwei Shen

Theses and Dissertations

Breast cancer continues to be the second most common cancer in women in the United States. The neuroendocrine hormone human prolactin (hPRL) plays an important role in normal mammary gland development and growth, stimulating normal breast tissue proliferation and differentiation. Considerable evidence has shown that hPRL is involved in the malignant transformation of human breast tissue. hPRL enhances viability, invasiveness, and proliferation of breast cancer cells in vitro. Evidence from epidemiologic and genetic studies also implicates role of hPRL in the pathogenesis of breast cancer. Its cognate receptor the human prolactin receptor (hPRLr) is required for the action of hPRL. …

Opioid System's Potential Involvement In Ketamine's Cognitive And Antidepressant-Like Effects In Rats, Fan Zhang

Theses and Dissertations

Depression stands as one of the most pervasive mental health challenges worldwide, including the United States. Conventional antidepressants typically display a delayed onset of therapeutic action (4-8 weeks) and lack efficacy in a substantial portion of patients (over 40% of depressed patients are treatment-resistant). The dissociative anesthetic ketamine, which is a glutamatergic N-methyl-D-aspartate (NMDA) antagonist, has emerged as a promising novel treatment due to its rapid and prolonged antidepressant effects, and it is especially beneficial for treatment-resistant depression. Nevertheless, the precise neurochemical mechanisms underlying ketamine’s antidepressant properties remain elusive, hampering the development of safer and more efficacious treatments. The present …

The Relationship Between Material Circumstances And Primary Care Utilization After Enrollment In Virginia’S Medicaid Expansion, Hannah Shadowen

Theses and Dissertations

Health and health equity encompass not only healthcare but individual level material circumstances like food and housing, neighborhood level conditions like local consequences of residential segregation, and state and federal policies like Medicaid expansion. However, we are just beginning to understand how state level health insurance policy changes operate in the relationship between material circumstances, healthcare use, and health outcomes. This work focuses on newly enrolled Virginia Medicaid expansion members by using both claims data and survey data collected at the point individuals enrolled in Medicaid expansion and a year after Medicaid coverage.

Paper 1 asks if newly enrolled Medicaid …

Bayesian Estimation Of Hierarchical Linear Models From Incomplete Data: Cluster-Level Non-Linear Effects And Small Sample Sizes, Dongho Shin

Theses and Dissertations

We consider Bayesian estimation of a hierarchical linear model (HLM) from small sample sizes. The continuous response Y and covariates C are partially observed and assumed missing at random. With C having linear effects, the HLM may be efficiently estimated by available methods. When C includes cluster-level covariates having interactive or other nonlinear effects given small sample sizes, however, maximum likelihood estimation is suboptimal, and existing Gibbs samplers are based on a Bayesian joint distribution compatible with the HLM, but impute missing values of C by a Metropolis algorithm via a proposal density having a constant variance while the target …

Development Of Novel Hydrogel Materials For Viscoelastically Accurate Brain Phantoms, Lila G. Schandler

Theses and Dissertations

Current methods such as concussion tests and Magnetic Resonance Imaging (MRI) scans only reveal structural damage post-injury. Creating an anatomically accurate model of the brain that mimics brain structure and viscoelastic properties will further allow medical professionals to analyze concussion events and create curated and personalized plans of recovery for a patient’s unique brain injury.

Values have been established for the necessary viscoelastic properties (time constants and elasticity) to mimic the native human brain tissue such as grey matter and white matter. The mechanical properties of the hydrogel are tunable by varying the concentration of Phytagel (PHY), a protein binding …

Observed Parent And Child Differences In Black Mothers Of Children With And Without Attention-Deficit/Hyperactivity Disorder, Sydney E. Padgett

Theses and Dissertations

Attention-Deficit/Hyperactivity Disorder (ADHD) is childhood's most common neuro- developmental disorder, mainly distinguished by a pattern of inattention, hyperactivity and/or impulsivity. Compared to the plethora of research on White children with ADHD, the research on Black children with ADHD is limited. Looking more closely at the functions related to parenting children with ADHD, there is even less information known on the interactions between Black children and their parents compared to White children and their parents. The primary aim of the thesis study was to compare observed parenting and child behaviors between Black mother/child dyads of children with and without ADHD. This …

Factors That Influence The Use Of Culturally Relevant And Responsive Pedagogies For Elementary School Leaders, Stephanie Lindstrom

Theses and Dissertations

The presence of minority students in public schools has highlighted the need for teachers and school leaders to seek and implement exclusive instructional strategies that will foster cultural diversity. The climate, culture, and vision of a school are a direct reflection of the school’s leadership. The purpose of this study was to explore the cultural readiness of elementary school leaders, as measured by the cultural readiness leadership scale (CRLS), and their beliefs and perceptions of culturally relevant and responsive practices. The foundational philosophy used to support this research was the transformational leadership theory. The research methodology entailed a mixed-method approach …

How Do Elementary Induction Teachers Perceive Video Coaching As A Job-Embedded Professional Development Strategy?, Ursala Maddox Davis

Theses and Dissertations

This qualitative narrative case study examines the perceptions of elementary school induction teachers on video coaching as a job-embedded professional development strategy. The research was conducted with 12 induction teachers from an urban school district in Georgia, utilizing questionnaires, focus groups, and individual interviews. Nine teachers participated in focus groups, and four in individual interviews. Initially, teachers expressed negative views about video coaching, primarily due to discomfort with being recorded. However, over time, increased self-reflection and structured mentor feedback led to a positive shift in perceptions. Teachers reported heightened self-awareness, instructional improvements, and a stronger emotional connection to their teaching …

Academic Performance And Educator Efficacy In Supporting Military-Connected Adolescents Among High Schools In A Georgia School District, Megan Louise Jones

Theses and Dissertations

The effects of a parent’s military service on their children are well-researched in the post-9/11 era, particularly for elementary-aged students. However, research involving adolescents is much narrower, despite 25% of all military dependents ranging between 9th and 12th grade. These students are already enduring major changes as adolescents, but military-connected adolescents are also navigating the many stressors of their family’s military affiliation. These students are oftentimes burdened by frequent moves, parental deployment, and acclimation to their circumstances. While the military family is acutely aware of the heightened stressors that potentially create chaos among the family unit, teachers’ awareness of these …

Photovoice As A Reflective Pedagogy For Undergraduate Community Psychology Students, Shereé Bielecki

Theses and Dissertations

This descriptive qualitative study was designed to understand the experiences of former Community Psychology (CP) undergraduate students who participated in a degree program at a California university. The purpose of this qualitative study is to explore how former Community Psychology undergraduate students describe their experiences using reflective Photovoice activities to learn about and become involved in social justice. The theoretical frameworks that informed this study were in social justice theory, pedagogical practices related to teaching social justice using Photovoice, and the practice of self-reflection in college classrooms. Two primary research questions guide the inquiry: 1) How do former Community Psychology …

Leadership In Social Service Non-Profit Organizations: An Interpreative Phenomenlogical Analysis Of Executive Leadership High Attrition Levels And Proposals For Change, Stephanie Fredericka Wanza

Theses and Dissertations

The purpose of this study is to address how leaders who are employed at non-profit organizations can utilize change management frameworks, leadership style, strategic planning and organizational best practices to reduce attrition levels at their organizations. The focus of this study is three-fold: a) to understand why high attrition takes place at non-profits; identify what change model/s, types of leadership styles and best practices can be effective in reducing leader attrition, b) explore the development of a leadership framework by understanding how to manage change at nonprofits through the Carnall (1986), Shields (1999) and Cummings and Worley (2009) change management …

How Political Elite Leverage Twitter To Polarize America, Woodson Morris Hobbs V

Theses and Dissertations

While social media has changed how humans use the internet, Twitter has drastically reformed how individuals worldwide receive their news. As news outlets fail to keep up with the rapid dissemination of information online, Twitter has become a sounding board for the political elite who leverage the platform's immediacy and virality. This study, using Quantitative Ethnography's Epistemic Network Analysis, seeks to determine if the political elite, specifically members of Congress, are leveraging Twitter to spread polarizing information to strengthen their base. In this study, extensive coding of select members of the 118th Congress was completed and compared to Voteview.com's DW-Nominate …

A Systematic Review Of Risk And Protective Factors For Mental Health Among Latinx College Students, Melissa Gavilanes

Theses and Dissertations

A quantitative studies systematic review with narrative synthesis was conducted to explore the risk and protective factors among Latinx college students’ mental health. This systematic review also aimed to identify the relevant demographic variability to the mental health of Latinx college students, and the relationship between mental health and academic performance within this population. Data was collected from four electronic databases and included peer-reviewed articles published between 2000 and 2022, conducted within the United States, participants over the age of 17, and samples comprised of or including Latinx college students. Studies utilizing quantitative designs, and quantitative portions of mixed method …

Psychological Safety During The Covid-19 Pandemic Restrictions-A U.S. Healthcare Context, Mary Jean Brown

Theses and Dissertations

The pandemic forced many employees to transition to remote work, leading to concerns about the economic impact and inequities between remote and on-site workers. The shift to remote work has raised psychological safety issues, work-life balance, and employee engagement. The virtual workspace created during the pandemic has highlighted communication challenges, interpersonal dynamics, and maintaining boundaries between work and personal life. Through a quantitative approach, this study explored changes in perceived psychological safety, its relation to the psychosocial impact of COVID-19, and demographic factors, offering the opportunity to gain insights into this unprecedented experience during a global pandemic. Findings showed that …

Beyond The Classroom: Unraveling The Impact Of Student Engagement On Graduation Rates In New York City, Kimberly Mccall

Theses and Dissertations

This study critically examined the impact of student engagement on high school graduation rates amidst the educational disruptions ushered in by the COVID-19 pandemic, with a concentrated focus on the United States. It evaluated the essential engagement factors--rigorous instruction, collaborative teaching, supportive environments, and trust--and their role in addressing disparities in graduation outcomes (New York City Panorama, 2022; Wang & Degol, 2014). Anchored in the theoretical frameworks of Bronfenbrenner’s ecological systems theory (Bronfenbrenner, 1979), social-emotional learning theory (Durlak et al., 2011; Williamson et al., 2015), and Vygotsky’s sociocultural theory (Vygotsky, 1987), this research utilized a comprehensive quantitative analysis of data …