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Algal Community Investigations: Present Day To Year-2100 For Mississippi Lakes And The Western Mississippi Sound, Emma Madison Tucker Dec 2024

Algal Community Investigations: Present Day To Year-2100 For Mississippi Lakes And The Western Mississippi Sound, Emma Madison Tucker

Theses and Dissertations

Algae play a key role in the aquatic environment as primary producers; however, they can form harmful algal blooms that are detrimental to the aquatic environment, people, and even the economy. It is generally believed that climate change will influence future algal blooms. The first study estimated algae community in three freshwater locations in Mississippi, Desoto Lake, White’s Creek Lake, and Columbus Lake, and one saline location, Western Mississippi Sound, using modern and new tools of the autonomous surface vessel, FlowCam, and EcoTaxa. From those results and leading into the second study was the application of four climate scenarios on …


Identification And Characterization Of The Antimicrobial Activities Of Pseudomonas Sp. Strain Wp18, Emma Suzanne Willis Dec 2024

Identification And Characterization Of The Antimicrobial Activities Of Pseudomonas Sp. Strain Wp18, Emma Suzanne Willis

Theses and Dissertations

Strain WP18 was isolated from disease suppressive soil of a soybean rhizosphere in the Mississippi Delta. Phylogenetic analysis supported that strain WP18 could represent a novel species within the genus Pseudomonas. This conclusion is supported by genome-wide bioinformatic analyses such as average nucleotide identity and genome to genome distance calculations. Further studies are needed to claim a novel bacterial species, which include cell fatty profiles, fingerprinting analysis, and polar lipid analysis based on the International Code for Nomenclature of Prokaryotes. Strain WP18 showed a broad-spectrum of antimicrobial activity against plant pathogenic bacteria and fungi that are economically important in agriculture, …


Projecting Land Cover Changes And Impacts On Bird Conservation Using Geographic Information System, Remote Sensing And A Cellular Automata – Artificial Neural Network Model In Nairobi National Park, Kenya., Frank Juma Ong'ondo Dec 2024

Projecting Land Cover Changes And Impacts On Bird Conservation Using Geographic Information System, Remote Sensing And A Cellular Automata – Artificial Neural Network Model In Nairobi National Park, Kenya., Frank Juma Ong'ondo

Theses and Dissertations

This study examines land cover changes and their projected future impacts on bird species conservation in and around Nairobi National Park, Kenya. 2016 and 2023 Satellite imagery, analyzed through Google Earth Engine and the MOLUSCE plugin were used to assess changes in five land cover types: grassland, shrubland, forest, urban, and water. Bird population data from the Kenya Bird Map were used to evaluate birds' responses to land cover changes. Birds were categorized into five habitat guilds—grassland-dependent, shrubland-dependent, forest-dependent, water-dependent, and urban-dependent bird species. Between 2016 and 2023, grassland and shrubland decreased by 14.21% and 5.54%, respectively, and urban increased …


Exploring Single Particles Through Optical Trapping And Advanced Laser Spectroscopy Techniques, Haifa Hassan Alali Dec 2024

Exploring Single Particles Through Optical Trapping And Advanced Laser Spectroscopy Techniques, Haifa Hassan Alali

Theses and Dissertations

This dissertation explores the innovative integration of optical trapping (OT) with advanced laser spectroscopy techniques to investigate the physicochemical properties of single particles from a variety of atmospheric aerosols, such as bioaerosols, terrestrial dust, and extraterrestrial dust. Each technique offers unique insights, significantly enhancing our understanding of these critical atmospheric components. The first work focuses on employing OT in conjunction with cavity ringdown spectroscopy (OT-CRDS) to measure the single-particle extinction of interplanetary dust particles at ultraviolet wavelengths (~308 nm). This method allows for the stable trapping of individual dust particles in air, facilitating precise characterization with minimal external interference. Our …


Mass Timber Utilization In Architecture: Carbon Sequestration, Building Materials And Construction Practices, Jacob Alan Gines Dec 2024

Mass Timber Utilization In Architecture: Carbon Sequestration, Building Materials And Construction Practices, Jacob Alan Gines

Theses and Dissertations

The built environment must innovate and adopt new materials and construction practices in order to meet current and forecasted environmental challenges, economic uncertainties and construction pressures. The specification of mass timber materials and building assemblies will play a major role in addressing these issues. The objectives of this research are fourfold: 1) Develop a deeper understanding among construction professionals of the role mass timber buildings can have in greatly reducing CO2 emissions through the use of renewable forest products and the storage of carbon in buildings; 2) Provide insights into the utilization of mass timber products for architectural application that …


Evaluating The Emergent Wetland Plant Juncus Effusus As A Tool In Phytoremediation Of Nitrogen And Copper, Jacob Aaron Hockensmith Dec 2024

Evaluating The Emergent Wetland Plant Juncus Effusus As A Tool In Phytoremediation Of Nitrogen And Copper, Jacob Aaron Hockensmith

Theses and Dissertations

Eutrophication is an increasing issue around the globe, including the Lower Mississippi Alluvial Valley where excess nitrogen runs into the Mississippi River and subsequently the Gulf of Mexico. The restoration of wetlands is one method that has been developed to help reduce nitrogen runoff, however, species selection should be done carefully as species selected must not only remove nitrogen but be able to compete with established species. Chapter II of this thesis investigates whether J. effusus is a viable candidate for use in this role. Additionally, copper contamination around the globe is increasing due to a variety of anthropogenic sources. …


Changing Attitudes And Increasing Fruit And Vegetable Intake Of Elementary-Aged Children Through School Gardens, Hayley Rae Meriwether Dec 2024

Changing Attitudes And Increasing Fruit And Vegetable Intake Of Elementary-Aged Children Through School Gardens, Hayley Rae Meriwether

Theses and Dissertations

Fruit and vegetable consumption is critical for children’s health, yet many fail to meet recommended intake levels. School gardens have the potential to increase consumption and improve attitudes toward fruits and vegetables. This study examined the impact of a school gardening program on children’s attitudes and consumption of fruits and vegetables using a pre- and post-test design. While most children reported enjoying gardening and trying new produce, no significant changes were observed in overall attitudes or consumption patterns after the intervention. However, increased consumption of apples and green beans was noted. The findings suggest that while school gardens can spark …


The Plastics Crisis: Responsible Recycling In Civil Engineering And Infrastructure, Jason Howell Stewart Dec 2024

The Plastics Crisis: Responsible Recycling In Civil Engineering And Infrastructure, Jason Howell Stewart

Theses and Dissertations

A global plastics crisis exists with around 400 million metric tons (MMT) of plastics production and 350 MMT of plastics waste generated annually around the globe. Plastics are durable and essentially non-biodegradable, so they accumulate in both terrestrial and marine environments as pollution and within landfills without breaking down over time. Plastics are ubiquitous in 21st-century society and culture, comprising essential elements in most industries including packaging, transportation, electrical/electronics, and building/construction. The role of civil engineering and infrastructure in addressing the plastics crisis was specifically explored. Responsible plastics recycling yields products with improved engineering properties, performance characteristics, marketability, and/or manufacturing …


An Analysis Of Suspension Days Among Students In Special Education And General Education In A Rural School District, Lakesia Falanda Bryant Dec 2024

An Analysis Of Suspension Days Among Students In Special Education And General Education In A Rural School District, Lakesia Falanda Bryant

Theses and Dissertations

An Analysis of Suspension Days Among Students in Special Education and General Education in A Rural School District, is designed to look at those disciplinary trends that directly affect our most vulnerable population of students, with an emphasis on suspension, expulsions and the rates at which special education students are suspended and/or expelled as compared to their non-disabled peers in a rural district in Mississippi. As the Mississippi State Department of Education cited this district for its high rate of suspension and/or expulsions of students with Individualized Educational Plans, this study is of significant importance in identifying those factors that …


Applied Behavior Analysis: Perspectives Of Mississippi Students Before They Enter The Educational Behavioral Consulting Field, Lauren Ashley Besong Dec 2024

Applied Behavior Analysis: Perspectives Of Mississippi Students Before They Enter The Educational Behavioral Consulting Field, Lauren Ashley Besong

Theses and Dissertations

This thesis analyzes how prospective Applied Behavior Analysis (ABA) professionals are enculturated through their educational pathways at one public university in Mississippi. I surveyed 24 current and prior students of the ABA program, as well as interviewed 1 prior and 10 current ABA students. Findings captured their perceptions of the field they are entering, through their experiences within the program. Results found that the ABA field appears to be split in a dual identity, existing in both educational and clinical spaces. Results showed that external perceptions of the institution viewed the ABA program as more clinical, while the students were …


Effects Of Eugenol And Carvacrol In Combination Against Salmonella In Hummus, Lauryn Ashley Heidelberg Dec 2024

Effects Of Eugenol And Carvacrol In Combination Against Salmonella In Hummus, Lauryn Ashley Heidelberg

Theses and Dissertations

Hummus consumption has risen but multiple foodborne outbreaks due to Salmonella contamination have been reported. Essential oils (EOs) eugenol and carvacrol have been found to inhibit the growth and survival of Salmonella in food products. The objective was to evaluate antibacterial properties of various concentrations of eugenol (EU) and carvacrol (CA), alone or in combination (EUCA) against Salmonella in vitro and in hummus. Eugenol demonstrated a MIC of 0.125 mg/mL and an MBC of 0.25 mg/mL, while carvacrol showed a MIC of 0.0625 mg/mL and an MBC of 0.125 mg/mL. In the hummus study, 2% EUCA was the most effective …


Identification Of Bacterial Species Composition And Diversity Of Chicken Breast Meat During Processing., Lizzie Raquel Zaldivar Dec 2024

Identification Of Bacterial Species Composition And Diversity Of Chicken Breast Meat During Processing., Lizzie Raquel Zaldivar

Theses and Dissertations

Understanding the bacterial profile of chicken during processing is essential to identify spoilage-related bacteria. Using advanced methods like Oxford Nanopore sequencing, specific bacterial species on chicken meat can be identified. This study aimed to characterize bacterial composition and diversity on chicken breast during processing. Results showed a reduction in aerobic bacteria, E. coli, coliform, and lactic acid bacteria counts. However, three thermophilic bacteria, Anoxybacillus contaminants, Neobacillus thermocopriae, and Anoxybacillus flavithermus, dominated across processing steps. Notably, Pseudomonas species were undetected by conventional plating but identified via Nanopore sequencing, highlighting the need for molecular detection methods. Although antimicrobial interventions significantly reduced bacterial …


The Effect Of Teacher Efficacy On Career Technical Education Program Participation In Select Mississippi Schools, Lori Parkman Nail Dec 2024

The Effect Of Teacher Efficacy On Career Technical Education Program Participation In Select Mississippi Schools, Lori Parkman Nail

Theses and Dissertations

The primary purpose of this study was to determine to what degree school staff understood the benefits and outcomes of Career Technical Education programs and how this level of understanding impacted Career Technical Education program enrollment in five selected schools in Mississippi. The levels of understanding keyed in on three pivotal factors. First, perceptions of the availability and accessibility of Career Technical Education programs to students in the participating schools were measured. Second, the perceptions of the benefits students reap from being involved in Career Technical Education programs were examined. Next, the perceptions of the benefits Career Technical Education programs …


Greener On The Other Side: Latinx Migrants’ Perspectives On The Importance Of Climate Change On Their Decisions To Relocate To Mississippi, Maria Claire Regalado Schrupp Dec 2024

Greener On The Other Side: Latinx Migrants’ Perspectives On The Importance Of Climate Change On Their Decisions To Relocate To Mississippi, Maria Claire Regalado Schrupp

Theses and Dissertations

As climate change continues to progress and impact people around the world, its impact on human migration has become a topic of increasing study and discussion. Debates over climate migration terminology and the extent to which it is a useful area of study have emerged in recent years. Yet, the opinions of migrants themselves are often missing from these conversations. Using mixed methods, this study uncovers the extent to which migrants from Latin America view climate change as relevant to their own migrations and, which factors, if not climate change, are most prevalent in inducing international migration to the United …


Description And Influence Of Diseases On The East Mississippi Catfish Industry, And The Role Of Clay Minerals, Iron, And Aluminum Salts In The Susceptibility Of Channel Catfish To Aeromonas Hydrophila And Edwardsiella Ictaluri, Mark Alan Peterman Dec 2024

Description And Influence Of Diseases On The East Mississippi Catfish Industry, And The Role Of Clay Minerals, Iron, And Aluminum Salts In The Susceptibility Of Channel Catfish To Aeromonas Hydrophila And Edwardsiella Ictaluri, Mark Alan Peterman

Theses and Dissertations

In 2014, a virulent clonal group of Aeromonas hydrophila (VAH) was the predominant disease impacting the east Mississippi (EMS) commercial catfish industry. The EMS aquatic ambulatory service observed an area not prone to VAH outbreaks. In addition, frequent underestimations of the scope and economic impact of the EMS catfish industry and its diseases warranted a descriptive effort. Therefore, the EMS catfish industry, its economic impact, the diseases of this region and their economic impact were described. Further, differences in water and geological chemistry of the area not prone to VAH outbreaks, and the sensitivity of VAH and Edwardsiella ictaluri to …


Development And Changes Over Time Of A Granola Bar Formulated With Sweet Potatoes, Meredith Kate Maynard Dec 2024

Development And Changes Over Time Of A Granola Bar Formulated With Sweet Potatoes, Meredith Kate Maynard

Theses and Dissertations

Sweet potatoes are a worldwide staple crop and granola bars are popular with consumers. This study aims to create a granola bar utilizing sweet potatoes and to assess its changes over time. Initial formulations tested minimum and maximum concentration of sweet potato (SP) puree, formulations, cooking type and time/temperature, humectants and preservatives. Bars containing 30 and 45% SP butter were chosen. Changes over time and descriptive sensory evaluation were conducted every 14d for 70d, with four treatments: a control bar and a bar with a preservative, each held at 25°C and 47°C. Water activity and moisture decreased by 0.05 and …


Invasive Bigheaded Carp Distribution Patterns In Oxbow Lakes Of The Lower Mississippi Alluvial Valley, Michaela Ann Palmieri Dec 2024

Invasive Bigheaded Carp Distribution Patterns In Oxbow Lakes Of The Lower Mississippi Alluvial Valley, Michaela Ann Palmieri

Theses and Dissertations

Large populations of Silver Carp (Hypophthalmichthys molitrix) and Bighead Carp (H. nobilis), collectively called bigheaded carps, may have significant impacts where they are invasive. In the Lower Mississippi Alluvial Valley (LMAV), bigheaded carps have been documented in major rivers; however, knowledge of their distribution in oxbow lakes is lacking. Species distribution models are tools that can be used to estimate species distribution with presence data and environmental variables. As a cost-effective alternative to onsite sampling, I administered a questionnaire to biologists to inventory bigheaded carp presence and obtained environmental data from existing datasets. I used Maximum Entropy (Maxent) to illustrate …


Reclaiming The Journey: A Phenomenological Study Of Black Lactation Professionals, Deandra Monet Kees Dec 2024

Reclaiming The Journey: A Phenomenological Study Of Black Lactation Professionals, Deandra Monet Kees

Theses and Dissertations

This study examined Black lactation professionals’ lived experiences navigating the human lactation workforce. Grounded in hermeneutic phenomenology and guided by Black feminist thought and critical race theory, this research unveiled the impact of various barriers that play a role in human lactation. While evidence cites the importance of human milk feeding, the voices of Black lactation professionals are often overlooked and marginalized, resulting in limited representation of Black lactation training practices. This study aimed to address a critical gap in the literature by centering the voices of Black lactation professionals. This research was conducted utilizing semi-structured interviews and a focus …


Evaluation Of Soybean (Glycine Max L.) Seed Inoculation With Bradyrhizobium Japonicum And Bacillus Subtilis On Yield And Root System Architecture: A Herbicide Carryover Perspective, Ncomiwe Andile Maphalala Dec 2024

Evaluation Of Soybean (Glycine Max L.) Seed Inoculation With Bradyrhizobium Japonicum And Bacillus Subtilis On Yield And Root System Architecture: A Herbicide Carryover Perspective, Ncomiwe Andile Maphalala

Theses and Dissertations

Reducing herbicide carryover in soybean production is imperative to sustain future soybean cropping systems in Mississippi and the rest of the world. This research was conducted to determine the response of inoculated soybean to corn (Zea mays L.) residual herbicides. The herbicide treatments included aatrex (atrazine), callisto (mesotrione), lexar (atrazine+mesotrione+s-metolachlor), and steadfast (nicosulfuron+rimsulfuron) at 100%, 75%, 50%, and 25% of the total label rate. Inoculant treatments were Bradyrhizobium japonicum, Bacillus subtilis, and no inoculant. Bacterial inoculants positively impacted most shoot and root growth parameters, significantly increasing depending on the herbicide x inoculant treatment combination and its rate. B.japonicum alone and …


Beyond The Classroom: Leveraging P-12 Education Brand Equity To Cultivate Community Capitals And Drive Economic Growth In Rural Mississippi, Patrick Braden Miller Dec 2024

Beyond The Classroom: Leveraging P-12 Education Brand Equity To Cultivate Community Capitals And Drive Economic Growth In Rural Mississippi, Patrick Braden Miller

Theses and Dissertations

This dissertation explores the relationship between education brand equity and community-economic development in rural Mississippi as a result of a consumer-oriented approach to education and manifested through the modern school choice movement. A survey of public school superintendents (n=28) found a statistically positive correlation, suggesting that a strong school brand leads to increased community-economic development. The Community Capitals Framework suggests this connection is due to interconnected capitals like human and social capital but helps other capitals rise as well. Additionally, superintendents overwhelmingly agreed collaboration between education and community-economic development is essential. The research also examined perceptions of school choice. Superintendents’responses …


Serving Students With Specific Learning Disabilities: Identifying Prevalent Eligibility Practices In Mississippi, Phyllis Marie Yucatonis Dec 2024

Serving Students With Specific Learning Disabilities: Identifying Prevalent Eligibility Practices In Mississippi, Phyllis Marie Yucatonis

Theses and Dissertations

This study investigated the determination eligibility practices for Specific Learning Disabilities (SLD) within Mississippi school districts, framed by the Individuals with Disabilities Education Act 2004 (IDEA) and Mississippi Department of Education (MDE) guidelines. A survey of 139 educational professionals in Mississippi offered insights into the methods preferred for determining SLD eligibility and the decision-making factors at the district level. The study examined commonly used methods for determining SLD, the challenges faced during the process, the need for professional development, the impact of educator demographics on SLD determination eligibility and general satisfaction with the SLD eligibility determination process. It also explored …


Evaluation Of The Physical And Mechanical Properties Of Hardwoods And Softwood Cross Laminated Timber, Richard Olakunle Omotayo Dec 2024

Evaluation Of The Physical And Mechanical Properties Of Hardwoods And Softwood Cross Laminated Timber, Richard Olakunle Omotayo

Theses and Dissertations

This thesis is focused on the evaluation of cross laminated timber made from southern pine lumber and low-grade hardwood species (which included red oak, sweetgum, and yellow poplar) growing in the southeastern part of the United States. The properties of interest were density, modulus of elasticity (MOE), modulus of rupture (MOR) and dynamic modulus of elasticity (dMOE). Mechanical testing using static bending technique was used to determine MOE and MOR and non-destructive technique (NDT) was used to predict dMOE. The results from mechanical testing showed that over 98% of low-grade hardwood CLT samples exceeded 8300 MPa. This proved the suitability …


Investigations Of Guayule Resin As A Wood Protectant, Queen Aguma Dec 2024

Investigations Of Guayule Resin As A Wood Protectant, Queen Aguma

Theses and Dissertations

Wood products are subject to deterioration by numerous processes, as a biological material. Today, a significant area of preservative development is the utilization of existing plant residues that have water-repelling, antibacterial, antifungal, and insecticidal properties as components of wood protectants. Parthenium argentatum, known as guayule (wy-oo-lee), is a promising wood protectant due to its resin. However, the resin's complicated chemical, physical, and solvent-resistant properties make it difficult to use. The primary goal of this study was to eliminate the use of any solvent and rely on thermal modification only to fractionate usable compounds from guayule resin. Utilizing heated dialysis and …


Deep Learning - Based Automated Detection And Classification Of Foreign Materials In Poultry Using Color And Hyperspectral Imaging, Rohini Maram Dec 2024

Deep Learning - Based Automated Detection And Classification Of Foreign Materials In Poultry Using Color And Hyperspectral Imaging, Rohini Maram

Theses and Dissertations

This thesis explores the use of Deep learning for detection and classification of small foreign materials (FMs) in poultry meat using color and hyperspectral imagery (HSI). The study employs You only look once (YOLO) object detection models on color images for precise localization, and one-dimensional convolutional neural network (1D CNN), two-dimensional convolutional neural network (2D CNN) was used on HSI (600 – 1700 nm) for classification. Twelve different FMs commonly known as polymers including PVC, PET, LDPE and HDPE, were examined using 52 color and 52 hyperspectral images. Four YOLO models (v5x, v7x, v8x, v10x) were implemented, trained, tested and …


Survival Analysis In The Presence Of Independent Or Dependent Censoring, Sakie Jaladha Arachchige Dec 2024

Survival Analysis In The Presence Of Independent Or Dependent Censoring, Sakie Jaladha Arachchige

Theses and Dissertations

This dissertation has three parts. The first part proposes a two-stage estimation procedure for a copula-based model with semi-competing risks data, where the nonterminal event is subject to dependent censoring by the terminal event. Under a copula-based model, the marginal survival functions of individual event times are specified by semiparametric transformation models, and a parametric copula function specifies the between-event dependence. The parameters associated with the marginal of the terminal event are first estimated, and the marginal parameters for the non-terminal event time and the copula parameter are second estimated via maximizing a pseudo-likelihood function based on the joint distribution …


Innovative Methyl Bromide Alternatives: Efficacy Of Acetic Acid Coated Ham Nets And Carboxymethyl Cellulose Films In Inhibiting Mite Infestations On Dry-Cured Ham, Sawyer Wyatt Smith Dec 2024

Innovative Methyl Bromide Alternatives: Efficacy Of Acetic Acid Coated Ham Nets And Carboxymethyl Cellulose Films In Inhibiting Mite Infestations On Dry-Cured Ham, Sawyer Wyatt Smith

Theses and Dissertations

Dry-cured hams may become infested with Tyrophagus putrescentiae (ham mites) during the aging process. Traditionally, methyl bromide (MB) fumigation has been used to control these infestations, but its phase-out due to environmental concerns has prompted the need for alternative methods. This study evaluated the effectiveness of acetic acid-coated ham nets and carboxymethyl cellulose (CMC)-based edible films with propylene glycol (PG) in mitigating mite infestations. Laboratory trials assessed the impact of these treatments on mite orientation, reproduction, infestation rates, and sensory quality. Results indicate that CMC films were effective at controlling mite growth and reproduction with minimal sensory impact. In contrast, …


Habitat Suitability Modeling For Optimizing Stand Initiation And Restoration Efforts Of Economically And Ecologically Important Hardwoods, Segun Michael Adeyemo Dec 2024

Habitat Suitability Modeling For Optimizing Stand Initiation And Restoration Efforts Of Economically And Ecologically Important Hardwoods, Segun Michael Adeyemo

Theses and Dissertations

This dissertation addresses critical challenges in forest management and restoration in the Lower Mississippi Alluvial Valley (LMAV) through a series of interconnected studies focused on improving habitat suitability modeling and growth prediction for oak species. The research employs advanced modeling techniques to enhance our understanding of species-habitat relationships and forest dynamics in the context of climate change. Initial studies focused on developing ensemble habitat suitability models for American chestnut (Castanea dentata) and butternut (Juglans cinerea), two historically important but currently threatened tree species. These models predict suitable habitats and potential range shifts under various climate change scenarios, highlighting the species' …


The Legal Environment Associated With Disputes From Conservation Easements On Private Property In The United States Of America, Thera J. Mullen Dec 2024

The Legal Environment Associated With Disputes From Conservation Easements On Private Property In The United States Of America, Thera J. Mullen

Theses and Dissertations

Conservation of natural resources on private land helps protect property against increasing civilization needs. Integrating conservation with property rights is necessary to understand conservation easements' implications as legally binding agreements. Conservation easements, used by different agencies, allow the land to remain privately owned while protecting natural conservation qualities. The legal aspects involve both creating the contract and enforcing it. Litigation becomes involved when the parties of the easement start to have disagreements. Little literature is currently present on this topic, so this study analyzed and summarized legal disputes related to conservation easements being implemented on private property. Some potential implications …


Review Of Inverter Functionality Requirements In Ieee 1547 For Voltage Fault Ride-Through, Tyler Coby Jonathan May Dec 2024

Review Of Inverter Functionality Requirements In Ieee 1547 For Voltage Fault Ride-Through, Tyler Coby Jonathan May

Theses and Dissertations

The introduction of Distributed Energy Resources such as energy storage systems, solar, and wind create system dynamics which modern electric grids cannot reliably handle in such large quantities without properly coordinated protections. One such tool is the concept of Fault Ride Through, which allows a system to continue operation during a long-term minor or short-term major disturbance. Standards are in place to control and monitor the operation and recovery of this capability but are meant to be minimum or maximum requirements. Since these standards must be used nationally, or sometimes internationally, they tend to be left very flexible. The rise …


Sulfhydryl-Containing Compounds And Iron Homeostasis: Mechanisms Of Labile Iron Pool Dysregulation And Consequences For Cellular Health, Steven Lowell Mann Christiansen Dec 2024

Sulfhydryl-Containing Compounds And Iron Homeostasis: Mechanisms Of Labile Iron Pool Dysregulation And Consequences For Cellular Health, Steven Lowell Mann Christiansen

Theses and Dissertations

While iron's unique coordination chemistry and redox activity have resulted in its broad incorporation into biological systems, dysfunction in key iron-regulating mechanisms can transform these biochemical advantages into factors that contribute to several pathological conditions. This dissertation explores the complex interactions between iron and sulfhydryl-containing compounds (SCCs), with particular focus on glutathione's (GSH) role in stabilizing iron reactivity juxtaposed with homocysteine's (Hcy) ability to disrupt iron homeostasis and promote disease progression. Through rigorous biochemical analysis and experimentation, we demonstrate that Hcy disrupts iron regulation through several mechanisms: (1) Hcy competitively displaces protective iron-binding molecules in the Labile Iron Pool (LIP), …