Digital Commons Network^™

Functional Dissection Of The Periplasmic Domain Of Rcsd, The Phosphotransfer Protein Of Escherichia Coli Rcs System, Abdelraouf Dapour

Theses and Dissertations

Microbial resistance to antibiotics poses a major health threat worldwide, prompting the scientific community to dedicate considerable efforts toward understanding the molecular mechanisms underlying this resistance. The Gram-negative cell envelope serves as a formidable barrier to environmental stressors and numerous antimicrobials. In E. coli and other enterobacteria, the Rcs system (Regulator of capsule synthesis) is a crucial two-component signalling pathway that plays a critical role in maintaining the integrity of the bacterial envelope. One unique aspect of the Rcs system is the involvement of several auxiliary proteins in its signalling cascade. Among them, RcsD, an inner membrane 100 kDa protein, …

Sustainability Transformation For Healthcare Facilities Following Net Zero Model, Esraa Elmitainy

Theses and Dissertations

The healthcare industry is a field undergoing huge development. Focused on SDG 3 “Good Health and Well-being”, the healthcare industry, as the main health service provider, was marked by experts as a sector that should lead sustainable development by example. The current work aims to formulate a sustainability rating system for new and existing healthcare facilities to encourage the Egyptian healthcare industry to move towards sustainability according to net zero concepts. Additionally, the transition to net zero waste is investigated though experimental work to test the possibility of utilizing sterilized medical waste in cement-based bricks.

The rating system starts with …

Rethinking Rupture And Continuity: Al-Jarād And Khamāsīn, Two Poetry Magazines Of The Egyptian 1990s, Caroline Benson

Theses and Dissertations

This thesis analyzes two Egyptian poetry magazines, al-Jarād and Khamāsīn, to enrich critical understanding of the Egyptian literary 1990s. It uses The Rules of Art: Genesis and Structure of the Literary Field (Les Règles de l’art: Genèse et structure du champ littéraire), Pierre Bourdieu’s 1992 sociological study of the literary field, as a theoretical framework. Numerous scholars have noted that the “nineties generation” is known for its aversion to politics, ideologies, and collectivities; its rupture with stylistic and thematic conventions of its predecessors; and its turn away from the “major issues” (al-qaḍāyah al-kubrā) of the …

Assessing Egypt’S Readiness To Introduce Program And Performance-Based Budgeting, Eman Negm

Theses and Dissertations

Program and performance-based budgeting is one of the recent and most controversial developments in the Egyptian budgetary system. As a results-based budgeting methodology, it can potentially support the government's endeavors to enhance the efficiency and effectiveness of public expenditures and improve the overall levels of transparency and accountability. As per the new Unified Finance Law, Egypt is preparing for the full implementation of the program and performance budgeting reform to start in FY 2027-2028. The main objective of this study is to assess the readiness of Egypt to introduce program and performance-based budgeting based on six main assessment pillars which …

Breaking Taboos: Syrian Women Reshaping Gender Roles In Zarqa, Jordan, Farah Qonaish

Theses and Dissertations

This research explores the changes in gender roles among Syrian refugee women in Jordan. Since 2011, more than a million Syrian refugees have settled in Jordan. Around 83% of Syrian refugees have resided in host communities in Jordan and around 70% of the Syrian population come from the rural areas in Syria refugees. Syrian refugees have experienced change on different levels of their lives since the beginning of the displacement. This ethnographic study was conducted in Zarqa, a major city in the middle region of Jordan, and a major host community for Syrian refugees in Jordan. The city is known …

Unveiling The Public Sector Hold: Egyptian Women And Work-Life Balance, Safa Gadelhak

Theses and Dissertations

Educated women in Egypt view the public sector as their preferred employer, irrespective of their educational level or recent efforts towards women empowerment and the rise of digitization. This study attempts to understand the perceptions of working women, through analyzing their reasons whether prominent or underlying to make this career choice. To better understand this behavior, twenty semi-structured interviews and two focus group discussions were conducted with a total of thirty women from both public and private sectors. The findings revealed that women gravitate towards the public sector mainly because of five reasons: (a) convenient working conditions, (b) feeling stuck, …

Expectations Versus Reality In New Cairo's Gated Communities: An Interdisciplinary Analysis Of Socio-Spatial Features, Ala'a Marwan

Theses and Dissertations

This research aims to introduce a new framework to identify the disparities between gated community residents’ experiences and real estate developers' visions towards the development. As New Cairo experiences significant growth, many residents are increasingly relocating to gated communities. It has become crucial to assess users’ expectations before moving and their lived experience post-moving to allocate the gaps between their expectations and reality, otherwise, the GC developments will grow apart from users’ updated preferences. The research focuses on the socio-spatial qualities such as accessibility to services and facilities, community interaction, and vast green areas between buildings for privacy, all of …

Evaluating The Performance Of Broccoli (Brassica Oleracea Var. Italica) In The Sandponics System Using Brackish Water With Biochar And Compost, Gabriel Oyebode

Theses and Dissertations

Some of the most pronounced effects of climate change on agricultural output include the depletion of freshwater resources and heightened salinization of arable land, especially in arid and semi-arid regions, adversely affecting crop yields. Many economic vegetable crops including members of the brassica family are sensitive to salt-stress. The use of organic soil amendments such as biochar and compost as complimentary nutrient sources in the sandponics system can improve the performance of crops. The study aimed to evaluate the effect of organic amendment on the growth performance and yield of broccoli and Nile tilapia (Oreochromis niloticus) under brackish …

The Role Of Social Support In Protecting Against Perinatal Depression Among Egyptian Women, Radwa Raafat Abdelshafi

Theses and Dissertations

Perinatal Depression (PND) is a global public health issue affecting many women as they transition to motherhood, and carrying detrimental consequences for both mothers and infants. Research in low and middle-income countries shows higher PND prevalence rates than in high-income and Western countries. In addition, social support has been shown to strongly protect or reduce the impact of PND. This study aimed to address a gap in research on PND in Egypt, and to build an understanding of the social support ecological system of new mothers. A survey was conducted with 81 first-time middle-class mothers living in Greater Cairo between …

The Principles Of Islamic Moral Philosophy And The Possibility Of Re-Conceptualizing Classical Islamic Aesthetics Of Architecture, Muhammad Feteha

Theses and Dissertations

This study is primarily concerned with the intersection of the moral and aesthetic theories of Abū Ḥāmid al-Ghazālī (d. 1111). Al-Ghazālī’s theory of aesthetics has been the subject of thorough scholarly investigations and diverse interpretations in the field of Islamic art history since the 1940s. This thesis critiques the premises upon which the use of al-Ghazālī’s writings in studies of Islamic art and architecture were built. It suggests that they lead to what could be described as “the contradiction of unethical beauty.” To overcome this contradiction, it offers a comprehensive interpretation of al-Ghazālī’s aesthetics through analyzing the concept ḥusn in …

Determinants Of Physicians' Brain Drain In Egypt, Mennatallah Elbeheiry

Theses and Dissertations

Egypt is enduring a significant shortage of physicians, despite the annual graduation of approximately 10,000 medical students from its 27 medical schools. In 2016, the physician density was alarmingly low, with only one doctor per 12,285 people. This shortage is exacerbated by a physicians’ brain drain, as Egypt is a leading exporter of physicians to countries like the United Kingdom and Australia. As of 2020, the Egyptian Medical Syndicate reported 212,835 registered physicians, yet 56 percent of them work abroad, and only about 62,000 are actively employed in public hospitals, serving a population of over 110 million. The government’s efforts …

The Role Of Biofilm Matrix On The Growth, Survival, And Diagnosis In Enterobacteriaceae, Kavi Bharathi R

Theses and Dissertations

Bacteria in nature live together encased in a matrix creating community ecosystems called biofilms, this structured space protects them from hostile environments. This study aimed to understand the role of the biofilm matrix in the growth and survival of Enterobacteriaceae. Our hypothesis proposes that subgroups of individuals within a biofilm can specialize in the production of different matrix components.

Matrix expression is metabolically costly, despite its unicellular simplicity, microbes can coordinate complex behaviour like sharing of matrix between producers and non-producers as an adept evolutionary strategy. Their resilience to stress during biofilm formation was studied to assess their abilities to …

Assessment Of Risk Factor Prediction Using Machine Learning Techniques And Hybrid Approach Based On Soft Sets, Menaga A

Theses and Dissertations

Cardiovascular diseases (CVDs) are the leading cause of mortality worldwide, and India reports a significantly high death rate due to its large population base and the increasing prevalence of non-communicable diseases. National statistics indicate that 20–27% of deaths in India are attributed to CVDs, with the proportion steadily rising over the years. Recognizing the urgency of early detection and risk prevention, the World Health Organization (WHO) introduced “The Global Action Plan for the Prevention and Control of Non-Communicable Diseases (2013–2020),” emphasizing early identification, risk reduction, and timely treatment. In this context, decision-making applications have gained importance across domains especially healthcare …

Behavioral And Neuroactivational Correlates Of Psychosocial Stress-Induced Cocaine Seeking In The Rat, Nicole Hinds

Theses and Dissertations

Abstract Nicole Maria Hinds BEHAVIORAL AND NEUROACTIVATIONAL CORRELATES OF PSYCHOSOCIAL STRESS-INDUCED COCAINE SEEKING IN THE RAT 2024 Molecular Cell Biology & Neuroscience Doctor of Philosophy Cocaine Use Disorder is characterized by a high risk for relapse that can persist over extended periods of abstinence. Psychosocial stressors are well-established to promote drug craving and relapse in humans but have rarely been employed in preclinical relapse models. Consequently, the underlying neural circuitry by which these stressors drive cocaine seeking has not yet been thoroughly explored. This project aimed to identify brain regions recruited during psychosocial stress-induced cocaine seeking in rats, with a …

A Precoding, Companding, And Nonlinearity Reduction Approach To Optimize High-Speed Ado-Ofdm For Visible Light Communication, Swaminathan S

Theses and Dissertations

Using light-emitting diodes (LEDs) for data transfer, visible light communication (VLC) presents a strong substitute for radio frequency communication. Yet, because of the non-linearity of LEDs, conventional Orthogonal Frequency-Division Multiplexing (OFDM) approaches in VLC are limited regarding spectrum efficiency, peak-to-average power ratio (PAPR), and system linearity. Multi-carrier asymmetrically Clipped Optical OFDM (MADO-OFDM) is introduced in this study. For VLC operations based on Optical Orthogonal Frequency Division Multiplexing (O-OFDM), a model-driven Deep Learning (DL) approach has been presented. Utilizing an Auto Encoder (AE) network technology reduced the non-linearity of the LEDs. A proposed improved ADO-OFDM protocol, called MADO-OFDM, adaptively modifies the …

Optimizing The Pass Program: Using Improvement Science To Enhance Holistic Support For First-Year Medical Students, Suzanne Julia Mosko

Theses and Dissertations

Medical students often face unique academic and personal challenges that can hinder their success and well-being, particularly in the first year. This dissertation examines the impact of the Proactive Academic Support System (PASS) Program, a program designed to provide timely, holistic support to first-year medical students. Guided by improvement science and the Universal Design Principles for Student Development Programs and Services framework, the study implemented two change ideas aimed at reducing the time between grade release and PASS meeting completion, thereby enhancing communication and engagement with students. The study focuses on one Plan Do Study Act (PDSA) cycle that assessed …

Daily Pain Experiences And Coping Approaches Among Women In Midlife With Elevated Risk For Cardiovascular Disease, Laura Travers

Theses and Dissertations

Millions of adults experience significant pain each year, costing individuals and our economy millions of dollars in lost productivity and negatively impacting quality of life. Pain is more common among women than men and is a known barrier to women’s physical activity (PA) engagement. Yet, PA helps manage pain and buffer against conditions such as cardiovascular disease (CVD). For women in midlife with CVD risk factors (e.g., hypertension), little is known about daily pain fluctuation and the coping skills employed to manage pain. The current study examined daily pain and pain coping experiences among women ages 40-60 with one or …

Using Rna-Sequencing To Explore Mechanistic Markers, New Therapeutics, And Immune Imbalance: A Study Of Cancer And Autoimmunity Through The Lens Of Triple Negative Breast Cancer, Systemic Lupus Erythematosus, And B-Cell Non-Hodgkin's Lymphoma, Naomi Lydia Rapier-Sharman

Theses and Dissertations

Cancer and autoimmune diseases both impose a substantial healthcare burden on the US and world populations. In 2016, there were over 17 million cases of cancer, leading to nearly nine million deaths. Additionally, autoimmune diseases cause substantial mortality and morbidity and are present in 3-5% of the general population. Despite the increased attention scientists now give diseases that are impacted by immune imbalance, we have yet to find regimens to treat the core cause(s) of tissue dysfunction without drastically decreasing the quality of life for many patients with either cancer or autoimmune disease. For instance, anti-CD19 Chimeric Antigen Receptor (CAR) …

Customized Feminine Hygiene Wash Containing Postbiotics From Lactobacillus Spp. To Treat Urinary Tract Infections (Uti), Veena G. Nair

Theses and Dissertations

Probiotics, which support host health by maintaining normal microbial flora, offer a promising approach for preventing recurrent infections. To evaluate the prophylactic potential of vaginal probiotics against urinary tract infections (UTIs), we conducted a study on 54 healthy South Indian women aged 18–40 who visited the Obstetrics and Gynaecology outpatient clinic at Trichy SRM Medical College and Research Centre between June and July 2022. Vaginal swabs were collected following ethical guidelines, and commensal microbiota were isolated for probiotic characterization, with the broader objective of developing a customized feminine hygiene wash enriched with vaginal postbiotics.

Lactobacilli cell-free supernatant (CFS) demonstrated potent …

Using Satellite Image Segmentation To Detect Trails, Jeremy Reynolds

Theses and Dissertations

This masters thesis proposes an innovative approach to satellite image segmentation by focusing on the detection and mapping of walking, hiking, and biking trails. The motivation behind this project comes from the underexplored area in segmentation techniques for trail identification and offers potential benefits for urban planning, environmental monitoring, and public health. The problem statement addresses the need for a model that can differentiate between various trail types and other natural or man-made elements. The project aims for efficiency and scalability in processing satellite imagery across different compute hardware. The work details several stages: researching existing segmentation techniques, specifically road …

Autistic Female University Students And Their Experiences With Depression: An Interpretative Phenomenological Analysis, Rosemarie Joy Hopkins Keenan

Theses and Dissertations

Autism spectrum disorder (autism) can have significant impacts on the lives of those who experience it. However, as autism can affect each person in unique ways, the exact impacts of the condition on a person's experiences are not well understood. This is especially the case for women and girls with autism, who are on diagnosed later in life and have historically been neglected in research studies when compared to autistic men and boys. Autistic people are underrepresented in university populations, and characteristics of a university education present new challenges for autistic students. Little research has been done to inform supports …

A Randomized Trial Of Heart Rate Variability Biofeedback Following Traumatic Brain Injury, Leah D. Talbert

Theses and Dissertations

Traumatic brain injury (TBI) affects over 1.7 million people annually in the U.S., often leading to autonomic nervous system (ANS) dysregulation and reduced heart rate variability (HRV), which may impact cognitive performance. This study investigated whether HRV biofeedback (HRV-B) improves HRV at rest and recovery after stress in individuals with TBI. Secondary aims examined links between HRV improvements and reductions in physical symptoms, enhanced emotional functioning, and better cognitive performance, as well as the role of practice adherence in moderating HRV-B effects. This randomized controlled trial compared HRV-B treatment to a sham control using a pre- and post-assessment design. Of …

The Latter-Day Saint Indian Placement Program: An Examination Through An Experiential Lens, Quinn Elise Christiansen

Theses and Dissertations

The Indian Placement Program, operated by the LDS Church from around 1947 to 2000, was influenced by the Church's belief in a connection between Native Americans to a Book of Mormon group known as the Lamanites. This group held a special status within the LDS Church because of their believed Israelite heritage as well as a prophecy promising their conversion in the last days. Spencer W. Kimball, motivated by both personal goals and his authority within the LDS Church, expanded on a successful experience of a young Native girl, Helen John, growing it into the broader Indian Placement Program. This …

The Epiphany, Maja-Lisa Flodin-Ali

Theses and Dissertations

Maja-Lisa Flodin-Ali explores her interest in constructing spaces and occupying sets, while navigating the complexities of living with a mood disorder. She draws parallels between the multilayered nature of New York City and the layers of her own identity, retracing her personal history and examining its impact on her art practice. By engaging with classic narratives, such as Alice in Wonderland and The Wizard of Oz, Flodin-Ali reframes her journey and personal history, using these stories as a lens to explore healthier and more sustainable approaches to making.

Victim/Perpetrator, David D. Moy

Theses and Dissertations

Throughout this text, David Moy will discuss the inner working of his investigation on image overload and materialization. Through tactics of blurring, erasure, and layering he achieves obfuscation in his printed media. In doing so, he questions the compounding nature of image/text that negate themselves in the larger context of time in the digital age.

Xxx, Samuel Tucker Claxton

Theses and Dissertations

In XXX Tucker correlates the rise in online hookup apps and the fall of queer nightlife spaces to show how the internet has affected gay cruising spaces. They relate their installation-based work to the ideas of liminal spaces and Jean Baudrillard's

hyperreal. Further, they contextualize their practice within the scope of Robert Grober's work.

Geospatial Machine Learning Approaches For Studying Urbanization Impact, Surface Reflectance Patterns, And Groundwater Health Risks, Bibhash Nath

Theses and Dissertations

Geospatial machine learning techniques have been used to study: the impact of urbanization on land use and land cover change, surface reflectance patterns in boreal regions, and groundwater health risks from arsenic in India. These studies combined spatial data, remote sensing, and predictive models to gain valuable insights for sustainable living and protecting human health.

Identifying Personality In Reptiles And Assessing Welfare Implications For Their Roles As Ambassador Animals In An Educational Setting, Valery Gonzalez

Theses and Dissertations

This study examined behavioral variability and personality in 13 reptiles used as ambassador animals at the American Museum of Natural History. Observations across seasons and novel object tests revealed individual differences, behavioral components, and correlations. Findings emphasize reptilian complexity, highlighting welfare implications while underscoring the need for further research.

Examining Risk Factors For Comorbidity Between Posttraumatic Stress Disorder And Obsessive-Compulsive Disorder In A Sample Of Trauma-Exposed Transgender Adults, Dylan Seeley

Theses and Dissertations

Comorbid PTSD-OCD post trauma exposure is understudied. Little research examines specific risk factors and marginalized populations. This study examined gender-based victimization, emotional avoidance, and executive functioning as risk factors. Findings suggest gender-based victimization is a unique gender minority stressor that may pose significant risk for transgender populations.

Factors Associated With Intimate Partner Violence Among Non-Binary Individuals Assigned Male At Birth (Nbamab), Ahmad Z. Mouazzen

Theses and Dissertations

One hundred-fifty partnered Nonbinary assigned male at birth (NBAMAB) people completed an online survey assessing experiences of intimate partner violence (IPV), and associated factors, including mental health, internalized and anticipated stigma, and relationship power and functioning. The results contribute to understanding of IPV among NBAMAB people, with further research suggested.