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The Association Of Anxiety, Familial Dysfunction, And Child Emotion Regulation Between Family Therapy Sessions 1 And 4, Kaelie Noel Lemmon Aug 2025

The Association Of Anxiety, Familial Dysfunction, And Child Emotion Regulation Between Family Therapy Sessions 1 And 4, Kaelie Noel Lemmon

Theses and Dissertations

Few studies address how relational factors may be interdependent and impact child-focused problems that could be collectively addressed in systemic family therapy. The current study utilized a cross-lagged panel model to explore the associations of parental anxiety, familial dysfunction, and child emotion regulation between four family therapy sessions. The study included 224 parents who sought family therapy and participated in the Marriage and Family Therapy Practice Research Network (MFT-PRN). Data were collected at two time points across four family therapy sessions. The findings indicated that higher levels of parental anxiety at intake were associated with higher familial dysfunction at session …


Investigating Radiation Induced Rowhammer And Retention Failures In Dram, Tyler Ricks Aug 2025

Investigating Radiation Induced Rowhammer And Retention Failures In Dram, Tyler Ricks

Theses and Dissertations

It is desirable for DRAM devices to be used in harsh radiation environments. Exposure to radiation causes DRAM cells to lose their retention time as their ability to store charge effectively declines. Exposure also worsens the effect of disturbance that causes neighboring cells to flip when a row is opened multiple times: an effect known as the Row Hammer Effect. This thesis evaluates the impact of radiation-induced memory cell degradation by comparing memory cell's retention time and their resilience to the row hammer vulnerability. Three generations of DRAM were placed under a neutron radiation beam. Sections of the irradiated devices …


Ai-Enabled Innovations In Automated Essay Scoring And Feedback Systems, Michael J. Murff Aug 2025

Ai-Enabled Innovations In Automated Essay Scoring And Feedback Systems, Michael J. Murff

Theses and Dissertations

This dissertation examines the evolution and educational implementation of Automated Essay Scoring (AES) systems, with particular focus on generative artificial intelligence integration in educational assessment. Through a two-article format, this research addresses the persistent gap between technical capability and educational adoption that has characterized AES development over seven decades. The first article presents a comprehensive methodological review analyzing 122 studies spanning AES evolution from foundational computational linguistics through contemporary hybrid systems. Despite achieving strong correlations with human scoring, modern AES systems face resistance due to validity concerns and misalignment with pedagogical values, revealing an "adoption paradox" where technical sophistication often …


First-Year Writing Student Perceptions Of Graduate Student Instructor Authority, Lacey Madison Hamilton Aug 2025

First-Year Writing Student Perceptions Of Graduate Student Instructor Authority, Lacey Madison Hamilton

Theses and Dissertations

Graduate student instructors (GSIs) are trusted to teach first-year writing (FYW) courses across U.S. campuses, yet many still wonder how their undergraduate students actually perceive their authority, especially when they're new to teaching or sharing a classroom with full-time faculty. While previous research has explored how GSIs view their own authority and how institutional structures shape their roles, we know far less about what students of these GSIs think. This study aims to fill that gap. Building on Reed and Ostenson's work in Big Comp, I conducted a mixed-methods study in Fall 2024 to hear directly from FYW students about …


Chemically Mediated Communication In Mound-Building Termites, Sree Subha Ramaswamy Aug 2025

Chemically Mediated Communication In Mound-Building Termites, Sree Subha Ramaswamy

Theses and Dissertations

Nest-building in social insects requires layered communication to coordinate complex, functional structures for housing, protection, storage, and homeostasis. This is especially striking in mound-building termites, which construct and repair large mounds collectively despite lacking image-forming eyes. This thesis investigates how Odontotermes obesus achieves such coordination through chemical communication embedded in soil.

Using controlled two-choice assays with manipulated soils, I separated airborne volatile signals from contact non-volatile signals by baking to remove volatiles, a mesh assay that presented volatile cues without contact, and solvent extraction with reapplication of contact cues. I quantified responses in major-only, minor-only, and mixed groups at two …


Compact Heterogeneous Architectures And Algorithmic Methods For Enhanced Real-Time Digital True Time Delay Beamforming And Radar Applications, Nathan Lynn Burnett Aug 2025

Compact Heterogeneous Architectures And Algorithmic Methods For Enhanced Real-Time Digital True Time Delay Beamforming And Radar Applications, Nathan Lynn Burnett

Theses and Dissertations

Modern radar and signal processing systems require efficient computational architectures to handle increasing data rates while still being able to maintain dynamic configurability and complex tasks. This thesis presents and explores hardware and algorithmic approaches addressing these demands across several different applications. First, a low-cost tracking platform and architecture for unmanned aerial vehicles (UAVs) is developed, which provides detection and tracking capabilities, compliant with new FAA remote ID regulations. Second, a GPU-FPGA based digital true time delay beamformer is implemented to achieve real-time wideband radio frequency interference (RFI) mitigation. Specifically this beamformer explores weight calculation and calibration through particle swarm …


Is Social Media Use A Reason For Socially Withdrawn Individuals' Mental Health Difficulties?, Angela Grundvig Aug 2025

Is Social Media Use A Reason For Socially Withdrawn Individuals' Mental Health Difficulties?, Angela Grundvig

Theses and Dissertations

Studies have found a link between subtypes of social withdrawal and internalizing problems throughout most of the lifespan. However, the work conducted in adolescence is much more limited including a lack of work examining factors that might mediate the association between forms of social withdrawal and internalizing problems. Social comparison may be one way in which social withdrawal predicts internalizing problems. There has been research showing that social media usage is associated with internalizing problems. The purpose of this study was to assess (a) the associations between three subtypes of social withdrawal (shyness, avoidance, and unsociability), respectively, and indices of …


Versatile Waveform Generation And Clocking Techniques For Rfsoc-Based Digital Designs, Michael David Jones Aug 2025

Versatile Waveform Generation And Clocking Techniques For Rfsoc-Based Digital Designs, Michael David Jones

Theses and Dissertations

Within an ever-evolving radio-frequency (RF) environment, designers are required to adapt systems to increasingly constricted parameters. The available tools continually grow to match this need, but so does the complexity in using them. The radio-frequency system-on-chip (RFSoC) is an innovation that combines a field-programmable gate array (FPGA) with an integrated RF chain. Designing with an RFSoC allows for high-precision data transmission, sampling, and processing, but it can be difficult and time-consuming to develop specialized circuits. The open-source CASPER project aims to provide a library of abstracted block-design components to simplify the design process. An arbitrary waveform generator (AWG) is created …


Attachment Or Aversion: A Study Of The Effects Of Parental Technoference On Child Emotion Knowledge, Brooklyn Coleman Aug 2025

Attachment Or Aversion: A Study Of The Effects Of Parental Technoference On Child Emotion Knowledge, Brooklyn Coleman

Theses and Dissertations

Young children's understanding of emotions is heavily socialized by their parents. Through interactions with parents, children learn what emotions look like, when they are expressed, and how they are labeled (Laible, 2004a). Interruptions to interactions between children and parents have the potential to influence the development of children's emotion knowledge. According to the DREAMER framework, how one family member uses media and technology can influence other family members (Barr et al., 2024). Technoference (i.e., digital distraction while with others) is one example of how media might interrupt family life and influence child development as a whole. The current study examined …


An Evaluation Of The Mississippi 4-H/Ffa Replacement Beef Heifer Development Contest, Lindsey V. Pansano Aug 2025

An Evaluation Of The Mississippi 4-H/Ffa Replacement Beef Heifer Development Contest, Lindsey V. Pansano

Theses and Dissertations

The Mississippi 4-H/FFA Replacement Beef Heifer Development Contest began in 2008 to provide youth with a contest to showcase their managerial skills relating to beef cattle. This study examined the impact of contest participation on development of life skills, technical skills, and choice of occupation. Youth and parents/guardians reported slight to moderate improvement in life skills. The same groups also agreed that technical skills were improved through contest participation. While most youth did not consider the contest to impact their choice of occupation, all indicated that they are currently involved in the beef cattle industry as adults. Overall, these results …


“It Just Builds Character”: Building The Bullying Myths Scale, Jessica Weiss Utley Aug 2025

“It Just Builds Character”: Building The Bullying Myths Scale, Jessica Weiss Utley

Theses and Dissertations

Approximately 20% of American children and adolescents report being victims of bullying each year (Irwin et al., 2022). Bullying victimization is linked to serious behavioral and psychological outcomes, like depression, anxiety, self-harm, and suicide (e.g., Chou et al., 2020; John et al., 2018; Mulder et al., 2017; Schoeler et al., 2018). Despite these sobering data, misconceptions continue to portray bullying as a normal part of growing up, that it is trivial in nature, and that some kids deserve to be bullied (Dawes et al., 2022; Kulig et al., 2008). This study tested the validity and efficacy of the Bullying Myths …


The Evaluation Of Tetflupyrolimet In Rice (Oryza Sativa), Dalton Ryan Whitt Aug 2025

The Evaluation Of Tetflupyrolimet In Rice (Oryza Sativa), Dalton Ryan Whitt

Theses and Dissertations

The evolution of resistance to many herbicide modes of action (MOA) threatens the utility of synthetic herbicides. Barnyardgrass control in rice has become increasingly difficult due to resistance to common herbicides, and no novel MOA has been introduced in 30 years. FMC Corporation recently discovered tetflupyrolimet (Dodhylex™ active), a Group 28 herbicide that inhibits dihydroorotate dehydrogenase. In 2023 and 2024, studies were conducted at the Delta Research and Extension Center in Stoneville, MS, to evaluate tetflupyrolimet for midsouthern U.S. rice production. The first study evaluated barnyardgrass control and rice tolerance with single and sequential applications of tetflupyrolimet with clomazone and …


Load Balancing For Stream Processing In Edge Computing, Faiza Akram Aug 2025

Load Balancing For Stream Processing In Edge Computing, Faiza Akram

Theses and Dissertations

Unlike cloud-based systems, where resources are centralized for data processing and located at a distance from the source, leading to an increase in the response time, edge computing emerges as a transformative paradigm that processes the data closer to the sources to meet the application’s service requirements. Since the resources in edge computing are distributed and limited, load balancing is crucial. To ensure the prevention of bottlenecks and failures in resource-constrained environments, load balancing is an important aspect of edge computing as it optimizes resource utilization while maintaining the requirements of low-latency applications, improved fault tolerance, energy efficiency, adaptability, scalability, …


Integrated Analysis Of Untargeted Liver, Serum Metabolome And Gut Microbiome Following Selenium Deficiency Diet In Selenoh Knockout And Wildtype Mice, Richard Eugene Baird Aug 2025

Integrated Analysis Of Untargeted Liver, Serum Metabolome And Gut Microbiome Following Selenium Deficiency Diet In Selenoh Knockout And Wildtype Mice, Richard Eugene Baird

Theses and Dissertations

Selenoprotein H (SELENOH) is an oxidoreductase located in the nucleolus, and its biochemical levels decrease with selenium (Se) deficiency, as reported in mammalian research. This current investigation aimed to understand the impact of nutritional Se deficiency on gut microbial composition and metabolomic profiles. The Firmicutes/Bacteroidota (F/B) ratio, linked to various health conditions, was balanced for wildtype (WT) mice (1.06). In contrast, selenoh knockout (KO) mice associated with dietary Se deprivation had a significantly (p < 0.002) lower ratio (0.56), suggesting dysbiosis. It is believed that SELENOH levels decreased due to the Se deficient diet, and the selenoh KO mice exhibited alterations in microbial community composition and metabolite profiles, as supported by correlative analyses. With respect to the bacterial communities, significant differences between diets occurred for three taxa, including Akkemansia mucinphila, Bacteroides caecimuris, and Parabacteroides goldsteinii. Candida tropicalis, Malassezia restricta, and Cyberlindnera jadinii were three abundant fungal yeasts. Only Cyberlindnera jadinii exhibited significantly greater relative abundance between genotypes and was more abundant in the selenoh KO versus WT mice. Correlation analyses between bacterial and fungal taxa revealed both positive and negative relationships, but no specific trends were observed. The liver and serum metabolomic data contained similar amino acids, lipids, proteins, and carbohydrates. Using NMR spectroscopy, 112 liver metabolites were detected, while GC-TOF-MS analysis of the serum revealed the presence of 172, comprising both polar and nonpolar compounds. The metabolite levels varied significantly when analyzed using multivariate models such as PCA and PLS-DA (VIP scores), particularly for glucose, taurine, lactate, and UDP-glucose, which are associated with energy production and cellular health. Overall, the Se deficient diet had the most significant impact on the microbial community structure and the concentration of key metabolites within liver tissues and serum. Correlation analyses conducted across studies revealed significant linear relationships between metabolites and the microbiome. However, these differences were associated with bacterial and fungal taxa containing low relative abundances. Based on these findings, further investigation into the impact of SELENOH homeostasis on microbial and metabolite profiles should be conducted using selenoh KO mice under various nutritional Se dietary levels.


Autonomous Generation Of Ids Rules From Threat Intelligence, Azim Bazarov Aug 2025

Autonomous Generation Of Ids Rules From Threat Intelligence, Azim Bazarov

Theses and Dissertations

Signature-based Intrusion Detection Systems (IDS) detect malicious activities by matching network or host activity against predefined rules. These rules are derived from Cyber Threat Intelligence (CTI), which includes attack signatures and behavioral patterns obtained through automated tools and manual threat analysis, such as sandboxing. The CTI is then transformed into actionable rules for the IDS engine, enabling real-time detection and prevention of threats. The constant evolution of cyber threats necessitates frequent rule updates, which delay deployment time and weaken overall security readiness. Recent advancements in autonomous agentic systems powered by Large Language Models (LLMs) offer the potential for automatic IDS …


Variables That Affect Designers’ Use Of Edible Planting In Residential Landscape Design, Emily Margaret Butler Aug 2025

Variables That Affect Designers’ Use Of Edible Planting In Residential Landscape Design, Emily Margaret Butler

Theses and Dissertations

Edible landscaping or “foodscaping” has had a resurgence into the mainstream. Though many trailblazers aim to encourage edible landscaping through homeowners and renters, there seems to be a lack of initiative from designers. To identify the variables that can affect a designer’s use of edible planting in the residential Southeastern United States, research and statistical methods were employed. Beyond interviewing an expert in the field of edible planting in the residential space, a survey consisting of both Likert and open-ended questions was sent to licensed landscape architects in the Southeastern U.S. The survey was conducted using Qualtrics and analyzed using …


Creating A Framework For Offering Alternative Credentials At Mississippi State University, Marian Montgomery Chancellor Aug 2025

Creating A Framework For Offering Alternative Credentials At Mississippi State University, Marian Montgomery Chancellor

Theses and Dissertations

As workforce demands evolve and learners seek more flexible, skills-focused education options, Mississippi State University’s College of Professional and Continuing Studies (CPCS) must innovate to remain responsive and competitive. This capstone project explores how MSU can design and implement a scalable framework for micro-credentials that align with employer needs, faculty expertise, and adult learner goals. Grounded in qualitative research, including interviews with faculty and industry leaders, the study identifies key workforce gaps—particularly in communication, leadership, and technical skills—and outlines a 6-stage development lifecycle for credential creation. Findings emphasize the importance of industry collaboration, applied learning, and policy support. The resulting …


Winter Waterfowl Forage Production In Managed Coastal Wetlands Of The South Atlantic Region: Improving Inputs For Bioenergetics Modeling Used In Regional Conservation Planning, Stephen Andrew Clements Aug 2025

Winter Waterfowl Forage Production In Managed Coastal Wetlands Of The South Atlantic Region: Improving Inputs For Bioenergetics Modeling Used In Regional Conservation Planning, Stephen Andrew Clements

Theses and Dissertations

Under the assumption that food is limiting to non-breeding waterfowl, Migratory Bird Joint Ventures frequently use daily-ration bioenergetics models to inform wetland conservation objectives. Two essential components of these models include estimates of energy supply (i.e., energetic density) of wetlands used by waterfowl and accurate spatial data layers to determine wetland area. Managed impoundments are important wetland resources for migrating and wintering waterfowl in the South Atlantic Region. However, there is little understanding of the energetic density available to waterfowl in these wetlands regionally, and until recently, a database of digitized impoundments was unavailable for developing a spatial data layer. …


Soil Ethics In Practice: Harvesting Conservation Choices Among Puerto Rican Coffee Farmers, Patricia Marie Cordero-Irizarry Aug 2025

Soil Ethics In Practice: Harvesting Conservation Choices Among Puerto Rican Coffee Farmers, Patricia Marie Cordero-Irizarry

Theses and Dissertations

Coffee farming in Puerto Rico has declined over recent decades, partly due to deteriorating soil quality. However, the decision-making process behind farmers’ adoption of soil conservation practices remains unclear, particularly the overlooked role of soil ethics, which emphasizes the moral principles guiding human relationships with the soil. This mixed-methods study examined coffee farmers’ adoption of soil conservation practices by integrating the Values-Beliefs-Norms (VBN) theory and a newly developed Soil Ethics Survey (SES) instrument for the quantitative component, while using Decision-Making Theory and Social Cognitive Theory to qualitatively explore how farmers’ experiences and reflections shape their soil ethics. Quantitative findings revealed …


Improving Engagement Through Readers' Theater: A Systematic Literature Review And Teacher Process Portfolio With Program Proposal, Karen K. Crum Aug 2025

Improving Engagement Through Readers' Theater: A Systematic Literature Review And Teacher Process Portfolio With Program Proposal, Karen K. Crum

Theses and Dissertations

This project investigated the impact of Readers’ Theater on elementary students’ attitudes toward reading, the teacher’s perception of effectiveness of Readers’ Theater as a tool to improve reading comprehension, and students’ test-related anxiety, within the context of the Mississippi Academic Assessment Program (MAAP) mandated by the Literacy-Based Promotion Act. While existing literature has highlighted Readers’ Theater as an effective instructional strategy that engages reluctant readers and enhances both reading fluency and comprehension through repeated, performance-based readings, gaps in current research exist regarding Readers’ Theater effectiveness as an instructional strategy to mitigate reading- and test-anxiety. Through research questions focused on how …


Social Validity Of Functional Analysis Variations, Rita M. Druffner Aug 2025

Social Validity Of Functional Analysis Variations, Rita M. Druffner

Theses and Dissertations

The functional analysis was developed to systematically identify the antecedent and consequent conditions mediating challenging behavior. Modifications to the traditional procedures have been developed to address barriers to implementation, including duration, environmental control, and safety. Much of the research surrounding functional analyses addresses effectiveness, barriers to implementation, and practitioner acceptability. However, there is a lack of research assessing caregiver social validity of functional analysis procedures. Social validity is the assessment of the goals, procedures, and outcomes of behavior analytic practice. Even though there has been advocacy for including measures of social within behavior analytic research and practice, there is limited …


Evaluation Of Furrow-Irrigation And Agronomic Management In Mississippi Rice (Oryza Sativa L.), Thomas W. Eubank Iv Aug 2025

Evaluation Of Furrow-Irrigation And Agronomic Management In Mississippi Rice (Oryza Sativa L.), Thomas W. Eubank Iv

Theses and Dissertations

A new non-transgenic rice has been developed called ROXY, which is resistant to formulations of oxyfluorfen. Utilizing the ROXY rice production system in a furrow-irrigated system could help combat troublesome terrestrial weeds and be a viable option for producers. To evaluate the performance of oxyfluorfen in furrow-irrigated ROXY rice production system, two concurrent field studies were conducted at the Delta Research and Extension Center in Stoneville, MS, from 2022 to 2024. The first study evaluated residual grass and broadleaf weed control with oxyfluorfen applied delayed-preemergence (DPRE). Factor A was oxyfluorfen rates of 0, 700, and 981 g ai ha-1. Factor …


Regulating Artificial Intelligence In The U.S.: A Historical-Innovation-Inspired Framework, Di Kevin Gao Aug 2025

Regulating Artificial Intelligence In The U.S.: A Historical-Innovation-Inspired Framework, Di Kevin Gao

Theses and Dissertations

The emergence of OpenAI\textquotesingle s ChatGPT has marked the dawn of a new Artificial Intelligence (AI) era, unleashing a wave of user excitement, moral panic, and apocalyptic warnings. Yet, these concerns have done little to slow the breakneck pace of AI development and deployment. Should the United States adopt the European Union\textquotesingle s top-down, legislation-first approach, or follow the United Kingdom\textquotesingle s bottom-up, court-driven model? This research draws from historical legislative parallels in the U.S. By examining past regulatory frameworks for disruptive technologies, including electricity, automobiles, the telephone, broadband internet, nuclear technology, cryptocurrency, commodity futures, modern pharmaceuticals, and social media, …


Understanding How Nws Meteorologists Tailor Hazardous Weather Messaging To Core Partners And Identify Local Vulnerabilities, Allison Camille Harvey Aug 2025

Understanding How Nws Meteorologists Tailor Hazardous Weather Messaging To Core Partners And Identify Local Vulnerabilities, Allison Camille Harvey

Theses and Dissertations

Over the past few decades, the National Weather Service (NWS) has continued to improve impact-based decision support services (IDSS) efforts to strengthen communication with core partners. This study addressed how a new spatially hazard-specific vulnerability tool called the Brief Vulnerability Overview Tool (BVOT) may impact how NWS meteorologists tailor messaging to their core partners. It was found that relationship building between NWS meteorologists and core partners is key to enhancing trust, especially during blue sky days. This was done by learning core partners’ needs, thresholds, and communication styles when presenting weather information. Core partners also noticed cues from NWS meteorologists …


Towards Applying Artificial Intelligence To Solve Np-Complete Problems Using Quantum Computing, Andrew Robert Haverly Aug 2025

Towards Applying Artificial Intelligence To Solve Np-Complete Problems Using Quantum Computing, Andrew Robert Haverly

Theses and Dissertations

This dissertation explores the methodology for more thoroughly entangling artificial intelligence and quantum computing. This is explored through a background search of problems solved using Grover’s quantum algorithm, a new quantum protein folding and drug discovery algorithm, using Grover’s algorithm to train quantum artificial neural networks, using quantum artificial neural networks for reinforcement learning, mapping classical assembly instructions to quantum circuits to make quantum programming easier, and using prompt engineering to get a classical artificial intelligence agent to solve an NP-Complete problem using a Grover’s algorithm. This method not only simplifies the creation of algorithms but also opens new avenues …


Tabletop Role-Playing Games As A Therapeutic Intervention: Translating Ttrpgs To Therapy, Joanne Adelle Hillerman Aug 2025

Tabletop Role-Playing Games As A Therapeutic Intervention: Translating Ttrpgs To Therapy, Joanne Adelle Hillerman

Theses and Dissertations

The purpose of this study was to examine the aspects of tabletop role-playing games, or TTRPGs, that are appealing to therapists, aspects of TTRPGs that may be challenging for therapists to implement, and to identify outside factors that may associated with therapists’ interest in using TTRPGs. This study used the technology acceptance model (Davis, 1989) as a theoretical framework. A sample of therapists and mental health workers (N = 102) answered survey questions on their perceptions of the ease-of-use and usefulness of TTRPGs in therapy, their likelihood to use TTRPGs in therapy, and additional items measuring outside influences on their …


Topnet R1: A Multi-Stage Ai Framework For Topic Discovery In Scientific Abstracts, Md Elias Hossain Aug 2025

Topnet R1: A Multi-Stage Ai Framework For Topic Discovery In Scientific Abstracts, Md Elias Hossain

Theses and Dissertations

Scientific abstracts are rich sources of knowledge, yet extracting meaningful topics remains challenging due to limitations in existing topic modeling techniques. Traditional methods often struggle with interpretability, scalability, and contextual understanding. To overcome these issues, we introduce TopNet R1, a multi-stage ensemble framework that integrates traditional topic models with contextual embeddings from Bidirectional Encoder Representations from Transformers (BERT) and Generative Pre-trained Transformer 4 (GPT-4) large language models (LLMs). Top- Net R1 operates in three phases: (1) topic generation using Latent Dirichlet Allocation (LDA), Non-Negative Matrix Factorization (NMF), Latent Semantic Analysis (LSA), and Hierarchical Dirichlet Process (HDP); (2) LLM-assisted pattern recognition …


Documenting Children’S Use, Physical Activity, And Social Play In Tom Lee Park’S Playscape, Laurel Kelton Aug 2025

Documenting Children’S Use, Physical Activity, And Social Play In Tom Lee Park’S Playscape, Laurel Kelton

Theses and Dissertations

The benefits of nature and physical activity on children’s health and development are well documented. However, many children lack access to nature and physical activity. Researchers have found that “innovative playgrounds” —which, by definition, are more likely to include natural elements that facilitate nature immersion— are associated with increased physical activity and duration of stay. This thesis is a case study of a public innovative playground at Tom Lee Park. It sought to understand the playground’s areas and physical characteristics that have higher levels of use, physical activity, and social play and longer durations of stay. Data was collected over …


Synthetic Mrna Induced Tf1.17-Specific Antibody Response Against Tritrichomonas Foetus For Preputial Delivery In Bulls, Kenzie Mcatee Aug 2025

Synthetic Mrna Induced Tf1.17-Specific Antibody Response Against Tritrichomonas Foetus For Preputial Delivery In Bulls, Kenzie Mcatee

Theses and Dissertations

Bovine trichomoniasis, caused by Tritrichomonas foetus, remains a persistent reproductive disease in cattle due to asymptomatic carriage in bulls and lack of effective treatments. This thesis evaluated the use of synthetic mRNA to drive expression of TF1.17- specific antibodies, targeting a conserved surface adhesin essential for parasite colonization. Membrane-anchored and secreted IgG1 constructs were transfected into bovine kidney cells, resulting in time-dependent antibody expression verified via NanoLuc luminescence. In vivo, aerosolized mRNA administration to bull calves led to localized antibody expression in preputial secretions. Although immunofluorescence assays detected fluorescence signal, high background limited interpretation of specific binding to T. foetus. …


Family Matters: How Caregiver Influence And Internal Locus Of Control Relate To Academics, Maia Mclin Aug 2025

Family Matters: How Caregiver Influence And Internal Locus Of Control Relate To Academics, Maia Mclin

Theses and Dissertations

Academics in college predicts life outcomes; students from lower socioeconomic status (SES) backgrounds often face greater challenges. One such population, consisting of many individuals from marginalized backgrounds, are those raised by nontraditional parents. This study investigated predictors of academics among 357 college students, examining authoritative parenting style, intrinsic motivation, academic locus of control (LoC), SES, and caregiver type (parental vs. non-traditional). Academics was assessed using two composite scores: 'academic knowledge' (GPA/ACT) and 'compensatory attention' (working memory via n-back task accuracy and attention/concentration via SMALSI-C). Hierarchical regressions revealed that higher authoritative parenting, higher SES, and being raised by biological parents significantly …