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Differential Regulation Of Mlc20 Phosphorylation In Tonic And Phasic Smooth Muscles Of The Stomach, Othman Al-Shboul
Differential Regulation Of Mlc20 Phosphorylation In Tonic And Phasic Smooth Muscles Of The Stomach, Othman Al-Shboul
Theses and Dissertations
Gastrointestinal (GI) smooth muscle possesses distinct regional and functional properties that distinguish it from other types of visceral and vascular smooth muscle. On the basis of electrical properties and contractile phenotype, GI smooth muscles have been classified into phasic (non-sphinteric) and tonic (sphinteric) smooth muscles. The biochemical basis of phasic and tonic phenotypes of smooth muscle is not clear and is the major question of inquiry of the present study. Phosphorylation of Ser19 on the 20 kDa myosin light chain (MLC) is essential for acto-myosin interaction and contraction in both phasic and tonic muscles. The levels of MLC20 phosphorylation are …
Between The Camera And The Gun: The Problem Of Epistemic Violence In Their Eyes Were Watching God, Katherine Ann Rich
Between The Camera And The Gun: The Problem Of Epistemic Violence In Their Eyes Were Watching God, Katherine Ann Rich
Theses and Dissertations
Since the 75th anniversary of the 1928 Okeechobee Hurricane in 2003, a growing number of journalists and historians writing about the disaster have incorporated Zora Neale Hurston's 1937 novel Their Eyes Were Watching God as part of the official historical record of the hurricane. These writers often border on depicting Their Eyes as the authentic experience of black migrant workers impacted by the hurricane and subsequent flood. Within the novel itself, however, Hurston theorizes on the potential epistemic violence that occurs when a piece of evidence—a photograph, fallen body, or verbal artifact—is used to judge a person. Without a person's …
Longitudinal Changes In The Corpus Callosum Following Pediatric Traumatic Brain Injury As Assessed By Volumetric Mri And Diffusion Tensor Imaging, Trevor Chuang Kuo Wu
Longitudinal Changes In The Corpus Callosum Following Pediatric Traumatic Brain Injury As Assessed By Volumetric Mri And Diffusion Tensor Imaging, Trevor Chuang Kuo Wu
Theses and Dissertations
Atrophy of the corpus callosum (CC) is a documented consequence of moderate-to-severe traumatic brain injury (TBI), which has been expressed as volume loss using quantitative magnetic resonance imaging (MRI). Other advanced imaging modalities such as diffusion tensor imaging (DTI) have also detected white matter microstructural alteration following TBI in the CC. The manner and degree to which macrostructural changes such as volume and microstructural changes develop over time following pediatric TBI and their relation to a measure of processing speed is the focus of this longitudinal investigation. As such, DTI and volumetric changes of the CC in participants with TBI …
Iain Baxter& And N.E. Thing Co.: A Study In Pop-Inflected Conceptual Art, Dennis Durham
Iain Baxter& And N.E. Thing Co.: A Study In Pop-Inflected Conceptual Art, Dennis Durham
Theses and Dissertations
The Canadian artist IAIN BAXTER&, known before 2005 as Iain Baxter, created an innovative Conceptual Art practice in the mid-60s that continues to make important contributions even today. He has maintained a strong collaborative element in his art, as witnessed by his role in the short-lived group IT (1965) and N.E. THING CO. (1966-1978)--an actual incorporated company consisting of BAXTER& and his first wife, Ingrid Baxter as chief officers--and by the addition of an ampersand to his legal name in 2005 to signify the open-ended quality of his work that relies on viewers‘ contributions to help determine its meaning. This …
Experimental Investigation Of Natural Fiber Reinforced Composite, Irene Samy Fahim
Experimental Investigation Of Natural Fiber Reinforced Composite, Irene Samy Fahim
Theses and Dissertations
There is a growing use of polymers in different applications worldwide. This phenomenon resulted in an enormous increase in the amount of plastic waste. These wastes have significant impacts on the environment including pollution and depletion of resources. Recycling plastic waste and reusing it helps in alleviating environmental degradation. The amount of recycled plastics all over the world not utilized is huge. U.S.A recycled 5.7% of the total plastics generated and Western Europe recycled 39% of total amount of plastics consumed [1]. This research studies the potential usage of virgin and recycled polymer reinforced with natural fiber such as rice …
Journey, Michael Mcgaugh
Journey, Michael Mcgaugh
Theses and Dissertations
My art explores the traditional elements of line, value, and texture. I use pencil and charcoal to create my drawings, and use the computer to alter and enhance my photographs. I also explore the relationships created through the combination of traditional and digital processes. Through the process of drawing, scanning, and layering images on the computer, I reveal details created by the contrast of these media. My goal is to successfully combine and balance traditional art practices with digital technology.
Characterization And Genetic Analysis Of The Cellulolytic Microorganism Thermobifida Fusca, Yu Deng
Characterization And Genetic Analysis Of The Cellulolytic Microorganism Thermobifida Fusca, Yu Deng
Theses and Dissertations
Currently, one of the hurdles hindering efficient production of cellulosic biofuel is the recalcitrant nature of cellulose to hydrolysis. A wide variety of cellulase enzymes are found natively in microorganisms that can potentially be used to effectively hydrolyze cellulose to fermentable sugars. Thermobifida fusca is a high G-C content, thermophilic, gram-positive soil actinobacterium with high cellulolytic activity. The phenomenological and mechanistic parameters affecting cellulase activity were studied in T. fusca and two mechanisms have been found: 1) transcriptions of cellulase-related genes were not closely associated with measured differences in cellulase activity and 2) cellular energetics (intracellular ATP) correlated more closely …
This Time Tomorrow And Other Painted Stories, Faylinda Kodis
This Time Tomorrow And Other Painted Stories, Faylinda Kodis
Theses and Dissertations
My visual vocabulary is drawn from the language of fairytales and dreams and includes animals, birds, tambourines, scrolled railings, clumps of flowers, clocks, bubbles, and people. I include symbols that resonate for me or, through its shape, solve a formal compositional problem. The images are pieced together in a collage-like manner and juxtaposed without regard to real world concerns of place, size, and scale. The resulting stories have a surreal appearance. My goal is to create drawings and paintings that reveal a personal, expressive reality.
Localization Of Open Educational Resources (Oer) In Nepal: Strategies Of Himalayan Knowledge-Workers, Tiffany Ivins
Localization Of Open Educational Resources (Oer) In Nepal: Strategies Of Himalayan Knowledge-Workers, Tiffany Ivins
Theses and Dissertations
This dissertation examines localization of Open Educational Resources (OER) in Himalayan community technology centers of Nepal. Specifically, I examine strategies and practices that local knowledge-workers utilize in order to localize educational content for the disparate needs, interests, and ability-levels of learners in rural villages. This study draws on insights from non-formal education (NFE) stakeholders in Nepal, including government, UN, international and national NGOs, local knowledge-workers, and learners from different villages. I specifically focus on a sample of seven technology centers to better understand how localization is defined, designed, and executed at a ground level. I illuminate obstacles knowledge-workers face while …
De Novo Genome Assembly And Snp Marker Development Of Pyrenophora Semeniperda, Marcus Makina Soliai
De Novo Genome Assembly And Snp Marker Development Of Pyrenophora Semeniperda, Marcus Makina Soliai
Theses and Dissertations
Pyrenophora semeniperda (anamorph Drechslera campulata) is a necrotrophic fungal seed pathogen of a variety of grass genra and species, including Bromus tectorum, an exotic grass that has invaded many natural ecosystems of the U.S. Intermountain West. As a natural seed pathogen of B. tectorum, P. semeniperda has potential as a biocontrol agent due to its effectiveness at killing dormant B. tectorum seeds; however, few genetic resources exist for this fungus. Here, the genome assembly of a P. semeniperda isolate using 454 GS-FLX genomic and paired-end pyrosequencing techniques is presented. The total assembly is 32.5 Mb and contains …
A Gis-Based Data Model And Tools For Analysis And Visualization Of Levee Breaching Using The Gssha Model, Hoang Luu Tran
A Gis-Based Data Model And Tools For Analysis And Visualization Of Levee Breaching Using The Gssha Model, Hoang Luu Tran
Theses and Dissertations
Levee breaching is the most frequent and dangerous form of levee failure. A levee breach occurs when floodwater breaks through part of the levee creating an opening for water to flood the protected area. According to National Committee on Levee Safety (NCLS), a reasonable upper limit for damage resulting from levee breaching is around $10 billion per year during 1998 and 2007. This number excludes hurricanes Katrina and Rita in 2005 which resulted in economic damages estimated to be more than $200 billion dollar and a loss of more than 1800 lives. In response to these catastrophic failures, the U.S. …
Usage And Development Of Molecular Markers For Investigation Of The Population And Ecological Genetics Of Bromus Tectorum L., Keith R. Merrill
Usage And Development Of Molecular Markers For Investigation Of The Population And Ecological Genetics Of Bromus Tectorum L., Keith R. Merrill
Theses and Dissertations
This thesis includes two studies: The first examined patterns of neutral genetic diversity within Bromus tectorum L. across the IMW region, and uses patterns of microsatellite (SSR) genotype distribution to make inferences about the respective roles of adaptively significant genetic variation, adaptive phenotypic plasticity, and facultative outcrossing in the ongoing invasion and recent range expansion of B. tectorum. It has been previously demonstrated that, due to extremely low outcrossing rates, it is possible to characterize individual genotypes of this species using four SSR loci. We sampled 20 individuals from each of 96 B. tectorum populations (classified by region and …
Apparent Competition With Bromus Tectorum Through Pyrenophora Semeniperda Reduces Establishment Of Native Grasses, Katherine Temus Merrill
Apparent Competition With Bromus Tectorum Through Pyrenophora Semeniperda Reduces Establishment Of Native Grasses, Katherine Temus Merrill
Theses and Dissertations
Contributing to the success of Bromus tectorum in the Intermountain West may be a mechanism called apparent competition, which occurs when one species increases the pressure of a consumer on a second species. This indirect interaction has been documented only a few times in invasive plant systems, and never in a fungal pathosystem. We examined the effects of the invasive annual Bromus tectorum and predation by the seed pathogen Pyrenophora semeniperda on seedling emergence and survival for two native grasses (Pseudoroegneria spicata and Elymus elymoides), by manipulating B. tectorum densities and P. semeniperda inoculum loads in randomized plots. …
A Proteolytic Process To Simulate The Mechanics Of Disc Dengeration In Bovine Cadaveric Tissue, Timothy A. Bishop
A Proteolytic Process To Simulate The Mechanics Of Disc Dengeration In Bovine Cadaveric Tissue, Timothy A. Bishop
Theses and Dissertations
Purpose. The present work hypothesized that proteolytic dissolution of intervertebral discs could induce biomechanical change comparable to the change observed in natural disc degeneration. A method to do such could be utilized for in vitro research where intersample differences in geometry and chemical makeup render it difficult to compare and aggregate results into generalized conclusions.
Methods. Forty-one bovine coccygeal intervertebral discs were isolated with individual functional spinal units. Samples were loaded in three modes: compression/tension, flexion/extension, and axial rotation. The anulus fibrosus of each disc was injected with 200µl trypsin or fetal bovine serum (control) and incubated for an allotted …
Developing Methods To Assess The Potential Effects Of Global Climate Change On Deer Creek Reservoir Using Water Quality Modeling, Reed Earl Chilton
Developing Methods To Assess The Potential Effects Of Global Climate Change On Deer Creek Reservoir Using Water Quality Modeling, Reed Earl Chilton
Theses and Dissertations
To evaluate the potential impacts of future climate change on a temperate reservoir, I used a calibrated water quality and hydrodynamic model validated using three years of data (2007-2009) from Deer Creek Reservoir (Utah). I evaluated the changes due to altered air temperatures, inflow rates, and nutrient loads that might occur under Global Climate Change (GCC). I developed methods to study GCC on reservoirs. I produced Average Water Temperature Plots, Stratification Plots, and Total Concentration Plots. Average Water Temperature Plots show the sensitivity of the water temperature to various parameters. Stratification Plots quantify stratification length and strength as well as …
Culvert Roughness Elements For Native Utah Fish Passage: Phase I, Lindsay D. Esplin
Culvert Roughness Elements For Native Utah Fish Passage: Phase I, Lindsay D. Esplin
Theses and Dissertations
Culverts can increase stream velocities as a result of reduced waterway areas and prevent upstream passage of small non-salmonid fish such as the Native Utah Leatherside chub (Gila copei) and Longnose dace (Rhinichthyscataractae). To mitigate this problem, current culvert design standards for fish passage match sustained fish swim speeds with average cross sectional velocity through the culvert. Such policies dictate relatively large barrels and do not recognize the role of reduced velocity zones near culvert boundaries. Obstacles and streambed substrate create turbulent regions with lower velocity zones that can increase upstream fish passage. A comparison of …
Easy To Find: Creating Query-Based Multi-Document Summaries To Enhance Web Search, Rani Majed Qumsiyeh
Easy To Find: Creating Query-Based Multi-Document Summaries To Enhance Web Search, Rani Majed Qumsiyeh
Theses and Dissertations
Current web search engines, such as Google, Yahoo!, and Bing, rank the set of documents S retrieved in response to a user query Q and display each document with a title and a snippet, which serves as an abstract of the corresponding document in S. Snippets, however, are not as useful as they are designed for, i.e., to assist search engine users to quickly identify results of interest, if they exist, without browsing through the documents in S, since they (i) often include very similar information and (ii) do not capture the main content of the corresponding documents. …
The Portrayal Of Older Characters In Popular Children's Books: A Content Analysis From 2000 To 2010., Jesica L. Danowski
The Portrayal Of Older Characters In Popular Children's Books: A Content Analysis From 2000 To 2010., Jesica L. Danowski
Theses and Dissertations
While picture books are often viewed as educational resources for young readers, it is crucial to not overlook the images and content this literary medium contains. Research suggests that repetitive messages encompassing a stereotypical nature cultivate lasting impressions on young audiences. One portrayal often associated with negative implications is the depictions of older characters in children's first literature. This investigation analyzed a selection of picture books from the New York Times best sellers list, the Book Sense best sellers list, and the Caldecott award winners for the years 2000–2010. In an attempt to provide a time spectrum communicating the levels …
Human Endogenous Sodium Pump Inhibitors Measurement, Source, Synthesis And Regulation, Jie Ma
Human Endogenous Sodium Pump Inhibitors Measurement, Source, Synthesis And Regulation, Jie Ma
Theses and Dissertations
The sodium pump (SP or Na+,K+-ATPase) is a membrane embedded protein complex that pumps 3 sodium ions out and 2 potassium ions into the cell per cycle and in so doing creates a cell membrane electrochemical potential. The membrane potential is critical for any functional cell. In the vasculature, reduction in the voltage potential causes vascular smooth muscle contraction and a narrowing of blood vessels (vasoconstriction) which can lead to increased blood pressure (hypertension). Substantial research over the past several decades has provided a vast amount of research on SP inhibitors, sometimes called endogenous digitalis-like factors (EDLF). Increased levels of …
The Effects Of Acute And Chronic Nicotine On Gaba And Dopamine Neurons In The Midbrain Ventral Tegmental Area, Devin Hardy Taylor
The Effects Of Acute And Chronic Nicotine On Gaba And Dopamine Neurons In The Midbrain Ventral Tegmental Area, Devin Hardy Taylor
Theses and Dissertations
Nicotine (NIC) abuse involves activation of midbrain dopamine (DA) neurons and NIC addiction involves neuroadaptive changes in the mesolimbic DA reward system. GABA neurons in the midbrain ventral tegmental area (VTA) express α4β2-containing nicotinic acetylcholine receptors (nAChRs), whose activation increases GABAergic input to DA neurons. However, this initial effect is decreased after chronic NIC treatment (as in the case of smokers) by inducing nAChR desensitization. Thus, GABA neuron inhibition results in increased DA release in limbic structures such as the nucleus accumbens. To support this hypothesis, we evaluated the effects of acute and chronic NIC on GAD-67 positive neurons in …
Biological Investigation Of The Stimulated Flapping Motions Of The Moth, Manduca Sexta, Travis B. Tubbs
Biological Investigation Of The Stimulated Flapping Motions Of The Moth, Manduca Sexta, Travis B. Tubbs
Theses and Dissertations
No abstract provided.
Evaluation Of Xmx/2l-Mil Virtual Impactor Performance And Capture And Retention Of Aerosol Particles In Two Different Collection Media, Jon E. Black
Theses and Dissertations
The United States Air Force uses the XMX/2L-MIL (XMX) high volume air sampler to collect samples for biological analysis. The XMX uses a virtual impactor to concentrate particles 1.0 to 10 μm in size into a secondary flow prior to sample collection using a liquid impinger in a collection tube. There are no known published studies regarding virtual impactor inter-instrument variability, effect of reducing the secondary flow on particle concentration, or capture and retention efficiency (CRE) of particles in the collection media performance characteristics when using the XMX. These performance characteristics were evaluated by lofting test aerosols of Arizona Road …
Development Of Optimized Guidelines For Therapeutic Strategies For Organophosphate Poisoning, Craig A. Holder
Development Of Optimized Guidelines For Therapeutic Strategies For Organophosphate Poisoning, Craig A. Holder
Theses and Dissertations
Organophosphates such as nerve agents have been used on several occasions in the past to inflict harm upon military and civilian populations in various parts of the world. The threat of these chemicals use against the military and civilians continues today, and the suggested treatment guidelines available may be ineffective or possibly cause harm. The guidelines investigated during the research presented here all included the use of two antidotes, atropine and oxime. The efficacy of oximes has been questioned and it has been suggested that they may cause harm to the patient. Both atropine and oxime are issued to military …
Modeling Vertical Flow Treatment Wetland Hydraulics To Optimize Treatment Efficiency, David T. Roen Ii
Modeling Vertical Flow Treatment Wetland Hydraulics To Optimize Treatment Efficiency, David T. Roen Ii
Theses and Dissertations
An upward Vertical Flow Treatment Wetland (uVFTW) at Wright Patterson AFB designed to bioremediate contaminated groundwater exhibits hydraulic short-circuiting. Prior studies estimated that groundwater flowed through less than 50% of the wetland’s volume, and that the mean residence time was significantly less than the nominal residence time, which was calculated assuming flow through the entire wetland volume. The objective of this research was to investigate how uVFTW hydraulics affects treatment efficiency, and to propose design strategies to maximize treatment efficiency. A groundwater flow and contaminant transport model of a uVFTW that couples hydraulics and degradation kinetics was built and applied …
Characterization Of Graphite Composite Material Particulates From Usaf Aircraft Maintenance Operations, Richard E. Yon
Characterization Of Graphite Composite Material Particulates From Usaf Aircraft Maintenance Operations, Richard E. Yon
Theses and Dissertations
Due to the benefits of their material properties, advanced composite materials (ACM) are increasingly being used as structural components on aircraft, especially within the United States Air Force. As a result, the potential exists for occupational exposures to structural maintenance employees while repairing and fabricating aircraft components. Two field studies were conducted for this thesis in order to characterize ACM aerosol size distribution, determine the feasibility of utilizing direct reading instruments (DRIs) in the field, and ensure workers are protected with adequate controls. In order to characterize exposure, traditional integrated air sampling and DRIs were positioned together near an ACM …
The Origins Of The Maya: A Comparative Analysis Of Narratives, Thomasina Ilene Morris
The Origins Of The Maya: A Comparative Analysis Of Narratives, Thomasina Ilene Morris
Theses and Dissertations
The purpose of this thesis is to document the changes in archaeological origin narratives concerning the lowland Preclassic Maya. This was accomplished by tracking the changes in four major narratives over several decades. These narratives include Herbert J. Spinden's Ancient Civilizations of Mexico and Central America; The Ancient Maya written by Sylvanus G. Morley, with additional editors, George Brainerd, Robert J. Sharer, and Loa Traxler; Michael D. Coe's The Maya, and Richard E.W. Adams's Prehistoric Mesoamerica. The specific parts of the narratives analyzed were the origins of agriculture, ceramic technology, writing, and monumental architecture. Changes in metaphorical language …
Characterization And In Vitro Toxicity Of Copper Nanoparticles (Cu-Nps) In Murine Neuroblastoma (N2a) Cells, Sitao Veronica Brownheim
Characterization And In Vitro Toxicity Of Copper Nanoparticles (Cu-Nps) In Murine Neuroblastoma (N2a) Cells, Sitao Veronica Brownheim
Theses and Dissertations
Nanomaterials, classified as materials within the 1 - 100 nanometer range, have seemingly endless applications. It is very important to the Air Force to increase the understanding of Cu-NPs and the possible health impacts from nanomaterial exposure prior to wide-spread industry and military use. Therefore, the purpose of this research is to thoroughly characterize the properties of three different copper samples upon suspension into aqueous solutions over time: Cu-NPs (Cu 25 nm), CuO-NPs (CuO 40 nm), and Cu-MSP (Cu 500nm). Additionally, this research seeks to observe in vitro effects upon murine neuroblastoma cells (N2A) by these three types of particles …
A Systems Architecture And Advanced Sensors Application For Real-Time Aircraft Structural Health Monitoring, Hyoungjin Shin, Edward C. Beckett
A Systems Architecture And Advanced Sensors Application For Real-Time Aircraft Structural Health Monitoring, Hyoungjin Shin, Edward C. Beckett
Theses and Dissertations
Aircraft are being pushed beyond their original service life, increasing the potential for structural failures. A catastrophic in flight failure of an F-15 bulkhead and severe cracking in the C-130 Wing rainbow fitting are two recent examples that have caused major problems for the Air Force. Previous Aircraft Structural Health Monitoring Systems research primarily explored using a system during the ground maintenance phase. This research will explore a Real-Time Aircraft Structural Health Monitoring System (RTASHMS) that includes a ground phase as well as an in-flight phase. The RTASHMS will continuously analyze structural hot spots, detect critical structural damage or cracks …
Experimental Measurements Of Store Separation Using Dry Ice Models In A Subsonic Flow, Michael C. Paul
Experimental Measurements Of Store Separation Using Dry Ice Models In A Subsonic Flow, Michael C. Paul
Theses and Dissertations
Testing free-drop store separation from a cavity in wind tunnels proves a difficult task because the models are typically destroyed during the test. Furthermore, there is potential for damage to wind tunnel components. Prior work has shown that small dry ice models released within the test section do not cause damage to the AFIT pressure-vacuum wind tunnel components or vacuum chamber. Rather, the dry ice models break apart and sublimate harmlessly into gaseous carbon dioxide. Therefore, this study was undertaken to determine whether dry ice models might prove useful in free-drop store separation testing. A generic aircraft cavity was constructed …
Sizing Analysis For Aircraft Utilizing Hybrid-Electronic Propulsion Systems, Matthew D. Rippl
Sizing Analysis For Aircraft Utilizing Hybrid-Electronic Propulsion Systems, Matthew D. Rippl
Theses and Dissertations
A submerged inlet investigation, using flow control in the form of discrete blowing, examined proximity and jet directionality to improve compressor face uniformity. The flow control locations were at the head of the ramp and part way down the ramp, providing four configurations under examination. Laser Doppler velocimetry (LDV)measurements at the throat determined the effect of the flow control based on the statistical velocity measurements. Blowing at closer proximity to the throat and targeting the largest velocity deficit region provided the best results. The airspeed and inlet velocity simulated takeoff and landing conditions; velocities ranged from Mach 0.1-0.3 at the …