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Force Optimization And Flow Field Characterization From A Flapping Wing Mechanism, Nathaniel Stephen Naegle

Theses and Dissertations

Flapping flight shows promise for micro air vehicle design because flapping wings provide superior aerodynamic performance than that of fixed wings and rotors at low Reynolds numbers. In these flight regimes, unsteady effects become increasingly important. This thesis explores some of the unsteady effects that provide additional lift to flapping wings through an experiment-based optimization of the kinematics of a flapping wing mechanism in a water tunnel. The mechanism wings and flow environment were scaled to simulate the flight of the hawkmoth (Manduca sexta) at hovering or near-hovering speeds. The optimization was repeated using rigid and flexible wings …

The Unclothed Body In Francisco Goya's The Disasters Of War, Elizabeth Sanderford

Theses and Dissertations

Francisco Goya (1746-1828) created a series of prints entitled The Disasters of War (1810-1820) (Los Desastres de la Guerra) depicting the Napoleonic Wars in Spain, the famine that subsequently occurred in Madrid, and symbolic representations similar to his print series Los Caprichos (1797-1799). This thesis will consider Goya’s use of the unclothed human body in his series of prints The Disasters of War. This thesis will place these representations within the contexts of other works produced by Goya that portray the unclothed figures, as well as within the Spanish artistic tradition of Goya’s time. Through this investigation, I will situate …

On The Genetic And Environmental Associations Between Body Composition, Depression Symptoms And Smoking Behavior., Roseann Peterson

Theses and Dissertations

Obesity is a serious public health crisis and recent estimates of its incidence are the highest in United States history, with 35% and 17% of American adults and children affected, respectively. The clinical definition of adult obesity is operationalized as a body mass index (BMI) greater than 30 kg/m2. Although the prevalence of common obesity has increased dramatically over the past 30 years–largely thought to be due to changes in the environment, such as high calorie diets and sedentary lifestyles—twin and family studies have shown consistently that relative body weight is under considerable genetic influence in both children and adults, …

Demographic And Genetic Consequences Of Small Population Size In Remnant Populations Of Arabis Georgiana Harper (Georgia Rockcress), Alicia M. Garcia

Theses and Dissertations

The goal of this thesis is to provide a greater scientific understanding of the demographic and genetic consequences of small population size in remnant populations of Arabis georgiana Harper (Georgia Rockcress). Specifically, 1 ) traits associated with phenological progression, fitness and reproductive success were compared between naturally occurring "native" plants and plants grown ex situ and subsequently restored to one of the largest remaining populations of A. georgiana, and 2) a preliminary analysis of population genetic structure in remnant populations across the species' range was performed. In addition to updating census information on remnant populations of A. georgiana, chapter one …

Supporting Children's Grief After A Death: A Guide For School Psychologists, Catherine Alexandra Bergeson

Theses and Dissertations

The death of a loved one is a significant stressor for children. Most children are exposed to grief at an early age. Without necessary support and guidance, children are much more susceptible to negative emotional, cognitive, and developmental effects. Expressive therapies such as bibliotherapy are supposed to provide a safe and healthy outlet for children's grief. However, school psychologists have limited pre-service training and readily available resources to effectively address children's death-related grief. This study included a survey of school psychologists from the National Association of School Psychologists (NASP) Crisis Management Group. Of the 431 potential members, 22% (N=95) responded …

Examining Alcohol Dependence And Its Correlates From A Genetically Informative Perspective, Laura Hack

Theses and Dissertations

Alcohol dependence (AD) is a serious and common public health problem that contributes to great societal, medical, and legal costs. It has taken work from multiple disciplines, including developmental psychology, genetic epidemiology, and molecular genetics, to achieve our current understanding of environmental and genetic risk factors for AD as well as its variable developmental trajectories. Nevertheless, there is still much to be learned in order to improve treatment outcomes. One approach to augmenting our understanding of this disorder is through genetically informative study designs that either examine risk in aggregate or assess specific susceptibility variants. In this dissertation, we utilize …

A Glyph And Animation-Based Visualization System For Evaluation And Comparison Of Soccer Players, Edward Burns

Theses and Dissertations

The dimensionality of soccer statistics relating to both player and goalkeeper specific data can be difficult to interpret. Attempting to formulate an analysis of large sums of soccer statistics can be extremely challenging if the data is not presented graphically. As a result, we developed an application, titled Soccer Scoop, which provides two separate visualizations that can aid a soccer team manager. With this application, a team manager can compare two players on different teams, analyze a particular player before signing them to a contract, measure the performance of a particular player at different positions, generate practice exercises, and determine …

Application Of Seawinds Scatterometer Data To The Study Of Antarctic Icebergs, Keith Mitchell Stuart

Theses and Dissertations

Knowledge of iceberg location and size is important for safety reasons as well as for understanding many geophysical and biological processes. This dissertation analyzes large tabular icebergs in the Southern Ocean using the SeaWinds scatterometer. SeaWinds is a spaceborne radar designed to measure the microwave backscatter from the Earth's surface. Using resolution-enhancement techniques, backscatter measurements are processed into backscatter images in which icebergs can be observed. An iceberg detection methodology is formalized using daily scatterometer images. Radar profiles from common Antarctic scatterers are quantified and an iceberg detection methodology is formalized using daily scatterometer images. Iceberg positions are determined in …

Using Genetic Information In Risk Prediction For Alcohol Dependence, Jia Yan

Theses and Dissertations

Family-based and genome-wide association studies (GWAS) of alcohol dependence (AD) have reported numerous associated variants. The clinical validity of these variants for predicting AD compared to family history has not yet been reported. These studies aim to explore the aggregate impact of multiple genetic variants with small effect sizes on risk prediction in order to provide a clinical interpretation of genetic contributions to AD. Data simulations showed that given AD’s prevalence and heritability, a risk prediction model incorporating all genetic contributions would have an area under the receiver operating characteristic curve (AUC) approaching 0.80, which is often a target AUC …

Novel Discretization Schemes For The Numerical Simulation Of Membrane Dynamics, Kyle F. Kolsti

Theses and Dissertations

Motivated by the demands of simulating flapping wings of Micro Air Vehicles, novel numerical methods were developed and evaluated for the dynamic simulation of membranes. For linear membranes, a mixed-form time-continuous Galerkin method was employed using trilinear space-time elements, and the entire space-time domain was discretized and solved simultaneously. For geometrically nonlinear membranes, the model incorporated two new schemes that were independently developed and evaluated. Time marching was performed using quintic Hermite polynomials uniquely determined by end-point jerk constraints. The single-step, implicit scheme was significantly more accurate than the most common Newmark schemes. For a simple harmonic oscillator, the scheme …

Using Public Relations Techniques To Market Organic Food: Understanding Consumer Buying Behavior, Catherine Girone

Theses and Dissertations

The purposes of this research were to determine which consumers tend to purchase fresh organic food and which consumers tend to purchase packaged organic food, which type of messaging organic food distributors rely on to entice customers and which messages work most effectively to promote organic food consumption, and which channels different organic consumers use to gain knowledge about organic food. Implications for organic food marketing are discussed.

Role Of Autophagy In The Response Of Hs578t Breast Tumor Cells To Radiation, Shweta Chakradeo

Theses and Dissertations

Breast cancer is the most commonly observed cancer type in women and is the second leading cause of cancer death in women. Radiation can be used to debulk tumors prior to surgery as well as to treat patients after surgery and/or chemotherapy. Previous studies from our laboratory have shown that the anti –malarial drug chloroquine sensitizes breast cancer cell lines to radiation by suppression of autophagy which is a conservative catabolic process that can be cytoprotective. The scientific literature has demonstrated that many tumor cell systems undergo cytoprotective autophagy and that pharmacological or genetic inhibition of autophagy leads to other …

Ground Vehicle Navigation Using Magnetic Field Variation, Jeremiah A. Shockley

Theses and Dissertations

The Earth's magnetic field has been the bedrock of navigation for centuries. The latest research highlights the uniqueness of magnetic field measurements based on position due to large scale variations as well as localized perturbations. These observable changes in the Earth's magnetic field as a function of position provide distinct information which can be used for navigation. This dissertation describes ground vehicle navigation exploiting variation in Earth's magnetic field using a self-contained navigation system consisting of only a magnetometer and magnetic field maps. In order to achieve navigation, effective calibration enables repeatable magnetic field measurements from different vehicles and facilitates …

Public Relations 'Tech'niques: Vocational School Recruitment, Rachel Graeff

Theses and Dissertations

The problem is that the large majority of high school graduates pursue four-year college degrees when there are not enough professional jobs that require four-year degrees but rather require workers to have job-specific skills. These skills are taught by vocational schools at both the high school and the post-secondary levels. The purpose of this study was to determine what public relations techniques vocational schools use and how they can improve on these techniques to increase enrollment. Six in-depth interviews were conducted with PR/marketing practitioners at vocational schools to find out what techniques and channels their school uses to attract students. …

Using Facebook To Improve Social Communication Skills Of Students With Autism Spectrum Disorders, Genna Graham

Theses and Dissertations

Facebook is a popular social media website that allows people to interact with friends and loved ones from far away and around the world. With its growing popularity, this study was conducted to examine if Facebook would improve social communication skills of students with Autism Spectrum Disorders. A total of nine students with ASD on two school campuses participated in the study. A multiple baseline single subject design across settings was used. During the baseline, students were observed and their initiation and reciprocation in communication with peers and teachers were recorded. During the intervention, students were instructed to use Facebook …

Post-Translational Regulation Of The Dopamine Transporter, Amy E. Moritz

Theses and Dissertations

The dopamine transporter (DAT) is an integral membrane phosphoprotein found on dopaminergic neurons that mediates the presynaptic reuptake of dopamine and is a site of action for psychostimulants. Numerous DAT functions including efflux, uptake activity, and surface expression are regulated by protein kinase C (PKC) through unknown mechanisms. Basal and PKC stimulated phosphorylation of DAT occurs on multiple serines in the distal N-terminus, but the exact sites modified and the kinases involved are unknown. To address these issues, we examined in vitro phosphorylation of a recombinant DAT N-terminal tail peptide (NDAT). We found that NDAT is phosphorylated at multiple sites …

Using Macroinvertebrate Community Composition To Distinguish Between Natural And Anthropogenic Sedimentation, Amanda E. Schutt

Theses and Dissertations

Excess fine sediment from human activity is a major pollutant to streams across the U.S.; however, distinguishing human-induced sedimentation from natural fine sediment is complex. The U.S. Environmental Protection Agency recently implemented a protocol for the quantitative field assessment of human-induced sedimentation using measurements of stream geomorphology. Macroinvertebrate community composition, streambed sediment stability, and sediment composition were studied at 49 sites in the James River watershed in central Virginia. Sediment composition was found to be a stronger driver of community composition than sediment stability. Although I was not able to show that macroinvertebrate metrics were related to sediment stability independently …

Keratin 6 As A Potential Biomarker Of Bladder Cancer Induced By Heavy Metals, Arsenic And Cadmium, Ling Cao

Theses and Dissertations

Arsenic and cadmium (Cd2+) are environmental carcinogens that have been implicated in the development of bladder cancer. However, there are no good in vitro model systems to study the development of bladder cancer caused by these carcinogens. Previous studies from this laboratory have shown that arsenite (As3+) and Cd2+ exposure can cause direct malignant transformation of an immortalized human urothelial cell line, the UROtsa. In the present study the repeatability of the transformation process was examined by isolating and characterizing 6 additional Cd2+- transformed lines and 5 additional As3+- transformed cell lines. All the transformed cell lines formed tumors when …

Virtual And Traditional Slides For Teaching Cellular Morphology To Medical Laboratory Science Undergraduates: A Comparative Study Of Performance Outcomes, Retention, And Self-Efficacy Beliefs, Brooke L. Solberg

Theses and Dissertations

As a result of massive retirement and educational program expense and closure, the field of Medical Laboratory Science (MLS) is facing a critical workforce shortage. Combatting this issue by increasing undergraduate class size is a difficult proposition due to the intense psychomotor curricular requirements of MLS programs. Technological advances in the realm of virtual microscopy, however, provide an opportunity to reach more students by delivering psychomotor components in less restrictive formats. The purpose of this study was to analyze pedagogical comparability of virtual slides and traditional slides regarding immediate and delayed performance, self-efficacy perceptions, student opinion, and faculty observations. Specifically, …

Preemptive Ketamine Administration, Carisa Zarr

Theses and Dissertations

Optimal pain management for the surgical patient is challenging for anesthesia providers. Finding new and improved methods of relieving surgical pain and evolving new techniques is an area of much research. The concept of preemptive analgesia suggests that the best postoperative pain management begins preoperatively (Morgan, Mikhail, & Murray, 2009). Preemptive administration of analgesic medications is used to stop pain from starting by blocking the nervous system's usual response to pain. This preemptive approach is thought to prevent wind up after the noxious stimulus of a surgical incision and can help prevent heightened sensitivity and lasting pain after surgery

Ketamine …

Loss Of The Lipopolysaccharide Core Biosynthesis Rfad Gene Increases Antimicrobial Chemokine Binding And Bacterial Susceptibility To Ccl28 And Polymyxin: A Model For Understanding The Interface Of Antimicrobial Chemokines And Bacterial Host Defense Avoidance Mechanisms, Cynthia S. Lew

Theses and Dissertations

In order to better understand the mechanism of antimicrobial chemokine activity, including binding to and killing of bacteria, random transposon mutagenesis was performed in Yersinia pseudotuberculosis. Resulting mutants were screened for increased binding to chemokine and high binding clones were selected for further study. One mutant, designated mutant 27, was found to have a single insertion mutation in the rfaD gene. The rfaD gene product is involved in heptose biosynthesis, one of the sugars of the inner core oligosaccharide of Gram- negative lipopolysaccharide (LPS). Mutant 27 was found to bind both CCL25 and CCL28, two antimicrobial chemokines, more efficiently than …

Using Student Response System (Srs) To Reduce Off-Task Behavior Of Students With Behavior Problems, Mary Johnson

Theses and Dissertations

The purpose of the present study was to examine the effect of clickers on decreasing off-task behavior of students with behavior problems in Language and math classes. A total of five students and one special education teacher in a self-contained classroom participated in the study. A single-subject research design with ABAB phases was used. An online program called "Class Dojo" was used to record study behavior with a chart immediately to show their on-task and off-task behavior. During the baseline, student behavior was recorded in both Language and math classes for 5 days. During the intervention phase, each participating student …

Role Of Nicotinic Acetylcholine Receptors In Experimental Colitis, Shakir Alsharari

Theses and Dissertations

Substantial evidence in the literature shows that tobacco smoking has complex and divergent effects on inflammatory bowel diseases (IBD). It ameliorates ulcerative colitis (UC); whereas it aggravates the risk of Crohn’s disease (CD) and affects the disease course and severity. Studies have shown that nicotine has a positive influence on symptoms of UC. Also, it is demonstrated that nicotinic acetylcholine receptor, especially α7 subunit plays an essential component in the vagus nerve-based cholinergic anti-inflammatory effects. In the present study, we explored the effect of nicotine and α7 nicotinic agonists treatment in the DSS colitis mouse model. We also investigated the …

Influence Of Electrostatic Charge Upon The Deposition Behavior Of Pharmaceutical Aerosols Within Cascade Impactors, Megha Mohan

Theses and Dissertations

Cascade impactors, routinely used for in vitro particle size characterization of pharmaceutical aerosols, are calibrated using dilute, charge-neutralized, monodisperse aerosols. But pharmaceutical aerosols are known to generate concentrated, inherently charged, polydisperse aerosol clouds. A computational model of the Andersen Cascade Impactor (ACI) suggested that the presence of charge on aerosol particles may influence their deposition within the ACI, but experimental validation of the model is warranted. This dissertation investigates the influence of electrostatic charge upon the deposition behavior of aerosols within cascade impactors, to address the impact of charge on particle size characterization. The influence of applied charge upon the …

Membrane Properties Involved In Calcium-Stimulated Microparticle Release From The Plasma Membranes Of S49 Lymphoma Cells, Lauryl Elizabeth Campbell

Theses and Dissertations

The mechanism of microparticle shedding from the plasma membrane of calcium-loaded cells has been investigated in erythrocytes and platelets. Recent studies have revealed the physiological and clinical importance of microparticle release from nucleated cells such as lymphocytes and endothelium. The experiments of this study were designed to address whether simple mechanisms discovered in platelets and erythrocytes also apply to the more complex nucleated cells. Four such mechanisms were addressed: potassium efflux, transbilayer phosphatidylserine migration, cytoskeleton degradation, and membrane lipid order. The rate and amount of microparticle release in the presence of a calcium ionophore, ionomycin, was assayed by light scatter …

Mechanical Properties Of Porcine Muscle In Compression And Tension With Microstructural Analysis, Renee Brook Pietsch

Theses and Dissertations

A need exists for a more robust method of evaluating musculoskeletal injuries resulting from impact conditions, particularly blasts. Computational modeling is a promising method of achieving this goal. The accuracy of a model depends on high quality mechanical properties for each component. This study examined the mechanical properties of porcine muscle along with structure property relationships. Fresh muscle was tested in compression and tension at strain rates of 0.1 s-1, 0.01 s-1, and 0.001 s-1. Viscoelastic properties were observed including strain rate dependency, stress state dependency, anisotropy, relaxation, and hysteresis. Image analysis was conducted in compression on controls, 30% strain, …

Micromechanical Analysis Of Cells From Hyperelastosis Cutis (Hc) Affected And Carrier Horses, Kenyatta Shanika Williams Washington

Theses and Dissertations

Equine hyperelastosis cutis (HC or HERDA), a connective tissue disorder in American Quarter Horses, results in hyperelastic skin with poor wound healing. Similar conditions are found in many species and all forms display decreased skin tensile strength. Fibroblasts produce collagen and elastin fibers, forming networks, providing the dermis with strength, and elasticity. This study aims to carry out a 3-part evaluation between horse skin fibroblast (cells from horses affected with HERDA, cells from horses that are carriers of HERDA (recessive HERDA gene), and cells from horses that are normal (neither affected or carriers of HERDA); Studies include: 1. Cell proliferation …

Potential Of Great Egrets To Be Vectors For The Transmission Of S Virulent Strain Of Aeromonas Hydrophila Between Channel Catfish Culture Pond, Madison Mccall Jubirt

Theses and Dissertations

Aeromonas hydrophila is a Gram-negative, rod shaped, facultative anaerobic bacterium that is ubiquitous to freshwater and slightly brackish aquatic environments and can cause infections in fish, humans, reptiles, and avian species. Recent severe outbreaks of disease in catfish aquaculture have been associated with a highly virulent Aeromonas hydrophila strain (VAH) that is genetically distinct from less virulent strains. Given that A. hydrophila is known to infect birds, we hypothesized that fish eating birds may serve as a reservoir for VAH and spread the pathogen by flying to uninfected ponds. Great Egrets were used in this transmission model because these wading …

Multi-Scale Den-Site Selection By American Black Bears In Mississippi, Brittany Winchester Waller

Theses and Dissertations

Dens are a critical component of black bear (Ursus americanus) habitat, yet scale-dependent den-site selection has received limited attention. Natural and anthropogenic factors (e.g., vegetation, roads) may also influence bear den-site selection. I quantified black bear denning chronology and den use and evaluated multi-scale den-site selection in Mississippi, USA during 2005–2011. Females entered dens earlier than males and emerged later; multiple den use by both sexes in a single winter was common. I recorded equal numbers of tree and ground dens, with ground dens at higher elevations surrounded by dense vegetation. Chronology and other denning characteristics of bears in Mississippi …

Educational And Informational Delivery Method Preferences Of Mississippi Beef Cattle Producers, Garrett Michael Steede

Theses and Dissertations

Due to the production costs associated with beef cattle production, it is important to equip beef cattle producers with sound, research-driven information to aid in the decision making process regarding their operation. Extension personnel as well as other organizations involved with beef cattle producers should be knowledgeable of the audience that they are disseminating information to and how this audience prefers to receive information. Knowing the demographics and educational and informational needs of the audience helps shape programming endeavors to meet the needs of the audience. The beef cattle producers surveyed indicated that they preferred to receive information from farm …