Digital Commons Network^™

Emotional Bond Between The Creator And The Avatar: Changes In Behavioral Intentions To Engage In Alcohol-Related Traffic Risk Behaviors, Hokyung Kim

Theses and Dissertations

The present study examines the joint impact of relationship with one's avatar and negative consequences to the avatar on changing behavioral intentions (CBI) in terms of alcohol-impaired driving. Avatars are users' visual self-representation in a virtual world, and play a major role to build the users' digital identity. One hundred eleven participants volunteered to participate in several experimental conditions where the degree of choice of avatar features and the degree of active control of the avatar were manipulated in Second Life, an immersive 3D virtual environment. Participants who were allowed to customize their avatar viewed their avatar more similar and …

Playing At History: Resurrection Man And Historiographic Game Design, Jessica Ethel Tompkins

Theses and Dissertations

This thesis investigates historical representation in video games and argues that two types dominate: 1) a semantic approach that engages players with the past via visual expressions; and 2) a cause and effect simulation approach that positions players in the context of historically situated possibilities. However, The author posits that the expressive power of video game worlds and mechanics afford deeper potentials for historical engagements. The author pursues a game design approach that takes seriously representations of the past and player inquiry at the forefront of the experience.

The historically contextualized video game is frequently discussed in the context of …

Gestational Weight Gain And The Risk Of Obesity Among Preschool Children: Is This Mediated Through Birth Weight?, Nomathamsanqa Louise Mgutshini

Theses and Dissertations

Data from the 2001 Early Childhood Longitudinal Study Birth- Cohort were used to examine the association between maternal gestational weight gain (GWG) and the risk of obesity in the offspring, and the possible mediating role of birth weight. The Centers for Disease Control growth 2000 reference charts and child's height and weight measured at age 4 or 5 years old were used to determine child body mass index (BMI) Z-scores or obesity status (greater than or equal to the 95th percentile). Multiple linear or logistic regression models were used to adjust for maternal age, race, education, smoking status and prepregnancy …

Diethylstilbestrol (Des) Mediates Immune Suppression Via Modulation Of Microrna Expression In Mice, Martine Menard

Theses and Dissertations

Diethylstilbestrol (DES) is a synthetic compound and considered as an endocrine disruptor that interferes with the normal development of human organs and even immune tissues. DES has been investigated for its immunosuppressive effects, thymic atrophy, and various types of cancer including breast cancer, ovarian cancer, uterine cancer, etc. In this study, we investigated DES regulated mechanisms in T cells and examined whether DES exposure of T cells leads immune suppression and affects immune functions. To this end, we investigated the effect of DES on T cells in vitro and specifically examined DES-induced apoptosis in T cells, expression of genes involved …

Synaptic Organization Of Noradrenergic And Opioid Circuitry In The Basolateral Amygdala: Anatomical Correlates Of Memory Consolidation, Jingyi Zhang

Theses and Dissertations

The studies comprising this dissertation were designed to investigate the synaptic organization of norepinephrine and opioid system in the anterior subdivision of the basolateral nucleus of amygdala (BLa) in rat. Light and electron microscopy were combined with immunohistochemistry to determine the synaptic incidence and postsynaptic targets of noradrenergic axon terminals, to localize mu opioid receptor at the ultrastructural level and to determine whether there is convergence of norepinephrine inputs and enkephalin inputs in the BLa. It was determined that about half of the norepinephrine inputs formed synapses in the BLa and the main postsynaptic targets were small caliber CAMK+ dendritic …

Novel Conditioning Protocols Focusing On Oxygen Manipulation To Enhance Stem Cell Transplantation, Brandon William Hanna

Theses and Dissertations

Musculoskeletal tissue engineering involves the creation of multiple tissue types that interact together to form a particular function related to motion and maintaining the body's frame. In order to create a fully functional musculoskeletal system, a concrete method for the creation of the different tissue types must first be completed. Of the different tissue components related to the function of a musculoskeletal system, these studies deal with preconditioning circumstances of stem cells that will differentiate into cartilage and bone. These studies also deal with methods for the creation of functional bone and cartilage to be combined for the creation of …

Rhetorical Ripples: The Church Of The Subgenius, Kenneth Burke & Comic, Symbolic Tinkering, Lee A. Carleton

Theses and Dissertations

Humor has long been an effective way to engage difficult sociopolitical topics in a way that avoids polemical confrontation and provides opportunity for pleasure, catharsis and self-knowledge. In the context of today’s polarized politics and protest, creative satirical performance that deploys “symbolic tinkering” can provide a “comic frame of reference” that, according to Kenneth Burke, more effectively conveys its message while providing reflexive insight. The satirical Church of the SubGenius naturally practices this rhetorical frame in their multimedia creations. Using the lens of Burke’s Attitudes Toward History, this essay is an analysis of SubGenius rhetoric with a focus on …

The E-Volving Picturebook: Examining The Impact Of New E-Media/Technologies On Its Form, Content And Function (And On The Child Reader), Stella K. Reinhard

Theses and Dissertations

The technology of the codex book and the habit of reading appear to be under attack currently for a variety of reasons explored in the Introduction of this Dissertation. One natural response to attack is a resulting effort to adapt in a bid to survive. Noël Carroll, leading American philosopher in the contemporary philosophy of art, touches on this concept in his discussion of the evolution of a new medium in his article, “Medium Specificity Arguments and Self-Consciously Invented Arts: Film, Video, and Photography,” from his Cambridge University Press 1996 text, Theorizing the Moving Image. Carroll proposes that any …

The Effect Of Obesity On Il-1Β, Il-1ra, And Leptin Following Acute Mental Stress, Heather Caslin

Theses and Dissertations

Research regarding the development of cardiovascular disease (CVD) is important because CVD is the leading cause of death in the United States (US) and many countries abroad. Risk factors, such as obesity and psychological stress, should be studied in order to understand contributing factors for CVD and the cellular mechanisms which link risk factors with the development of disease. Specifically, the combined influence of multiple risk factors on inflammation is of interest because many individuals have more than one risk factor, which additively increases an individual’s risk for CVD. Obesity is already characterized by disordered inflammation, which suggests that the …

Regulation Of Ykl-40 In Sterile Inflammation And Its Role In Glioblastoma In Vivo, Reetika Bhardwaj

Theses and Dissertations

YKL-40 is a secreted glycoprotein, which is a shared biomarker of chronic inflammation and oncogenic transformation. Indeed, YKL-40 expression is up-regulated in many diseases including multiple sclerosis, Alzheimer disease, viral encephalitis, HIV-associated dementia, brain infarction, and traumatic brain injury. YKL-40 is also expressed by several solid tumors, such as osteosarcoma, ovarian carcinoma and glioblastoma multiforme (GBM). It promotes the migration and invasion of astrocytes as well as GBM cells. Serum YKL-40 levels have been shown to directly correlate with tumor grade and potentially tumor burden in GBM. In contrast to the numerous reports documenting elevated expression of YKL-40, relatively little …

Vintage Anxiety, Bradford Pearce

Theses and Dissertations

Poems

"Mining" For A Reference Condition In Southern West Virginia Streams, Matthew Rouch

Theses and Dissertations

Quarterly samples were used to estimate assemblage-level (all species combined) fish production within three minimally-impacted, southern West Virginia streams. The total annual fish production estimate was highest in Slaunch Fork (37.52 kg∙ha^-1∙y^-1), a tributary of the Tug Fork River, and lowest in Cabin Creek (10.59 kg∙ha^-1∙y^-1), a Guyandotte River tributary. Creek Chub Semotilus atromaculatus, Mottled Sculpin Cottus bairdii and Blacknose Dace Rhinicthys atratulus were the most abundant species among sites, accounting for >90% of all sampled individuals. Reference condition criteria were also selected and metrics calculated for each of the three …

Examining The Effects Of Human-Animal Interaction On Individuals With Developmental Disabilities, Jennie Feinstein

Theses and Dissertations

Companion animals play a pivotal role in typical human development. It remains unknown how animals affect individuals with developmental disabilities. Based on the knowledge that companion animals help typically developing individuals, this research examined the effects of human-animal interactions on individuals with developmental disabilities.

Human-animal interactions are based on the Biophilia hypothesis, an assertion that an emotional and beneficial relationship exists between humans and nature, in which there is an “innate tendency to focus on life and lifelike processes.” These are the shared, dynamic associations between people and animals, and the effects of those relationships on health and well-being. Sparse …

Clarissa's Suffering: Theorizing Sympathy And Physical Pain In The Eighteenth Century, Audrey Hungerpiller

Theses and Dissertations

This thesis examines theories of pain in the eighteenth century, and what it meant to sympathize with the pain of another. I begin briefly with the theories of Descartes and his adherents before focusing on David Hartley and John Locke. Physicians and natural philosophers of the period understood pain as a pure mechanism of the nervous system, confined to the tubelike fibers that run through the body. Naturally everyone feels pain by some means, whether illness or injury, so men ought to be able to sympathize with the afflictions of others. Yet, according to Adam Smith in The Theory of …

Anthropogenic Ecological Impacts Of 17th And 18th Century Chickasaw Through A Study Of Faunal Remains, Marybeth Harte

Theses and Dissertations

A diachronic analysis of five faunal assemblages from Chickasaw sites is carried out to evaluate their anthropogenic ecological impacts during the colonial time period (A.D. 1650-1750). Change in faunal exploitation, diversity measures and disturbance taxa frequencies are analyzed to gauge these impacts. A comparison with late Mississippian period faunal use provides a benchmark to examine how shifts in the cultural system initiated new ecological impacts. Results from the faunal analysis are also compared with reports of faunal utilization and landscape management practices in the historical record. These reports provide a basis for assessing change in prey preferences according to the …

The Development Of A Performance Progression For Science Teachers' Implementation Of Model-Based Teaching, Christopher Bogiages

Theses and Dissertations

The Next Generation Science Standards (NGSS) call for science teachers to implement pedagogical strategies that can approximate authentic scientific practices. One such strategy, Model-Based Teaching, engages students in learning the disciplinary core ideas of science through the process of developing and using Scientific Models. Model-Based Teaching is a difficult pedagogical strategy for teachers to learn and implement. Factors such as Knowledge of Scientific Models and Modeling (KSM), understanding of the Nature of Science (NOS), and use of questioning to facilitate whole class discussions play important roles in the development of teachers' ability to implement Model-Based Teaching. This study employed a …

The Charleston "School Of Slavery": Race, Religion, And Community In The Capital Of Southern Civilization, Eric Rose

Theses and Dissertations

This dissertation explores the interracial religious communities of antebellum South Carolina to highlight patterns of racial consciousness and nation-building and demonstrate that the southern path to modernity was much closer to that of their northern contemporaries than previously recognized. The ready-made system of human classification inherent in racial slavery did not insulate southerners from the modern impulses that transfigured northern racial relations; instead, this dissertation argues that Carolinians white and black, free and slave, participated in a discourse of religious modernization that redirected the potentially destabilizing social implications of evangelicalism and progress into an idealized community structure that served the …

What Stages In The Phenology Of Corn Are The Most Correlated With Rainfed Corn Yields In The Corn Belt Using Remote Sensing?, Zachary Lee Braun

Theses and Dissertations

Two weekly and freely available remotely sensed vegetation indices, Vegetation Condition Index (VCI) and Temperature Condition Index (TCI), were assessed for state level corn yield correlation in the Corn Belt region of the United States for the years of 2007-2013. VCI and TCI were 16-km pixels which are derived from the Advanced Very High Resolution Radiometer (AVHRR). Corn pixels were identified by downloading yearly USDA Cropscape pixels for corn in each state. Irrigated corn pixels were removed by using the 2007 Irrigated Agriculture Dataset developed by Pervez and Brown (2010) as a mask. Corn pixels were then resampled to 16-km …

Role Of Bipa As A Modulator Of Gene Expression And Ribosome Assembly In Escherichia Coli, Promisree Choudhury

Theses and Dissertations

In Escherichia coli, ribosomes are the basic protein-synthesizing cellular machines. Hence, regulation of ribosome synthesis and assembly as well as regulation of protein translation are very important for bacterial cells. However, the cellular mechanisms of both these processes are not yet completely understood and thus both are active fields of research. It has been suggested that the BipA protein is involved in the regulation of both these processes. The research described here focused on understanding the cellular function(s) of BipA in regulating protein synthesis and ribosome assembly.

BipA is a member of the elongation factor family of translational GTPases …

Software Documentation Guidelines For Maintainability, Justin Roger Huber

Theses and Dissertations

Software maintenance is the final stage in the software engineering process; and can also be the longest and most costly. The ability of, and ease in which software upkeep and change is performed is an important software quality attribute called maintainability. Software maintenance however is an expensive process in both time and financial cost and can account for a majority of a system's overall lifetime cost. It would be beneficial then to have a set of guidelines for obtaining a higher degree of maintainability in software before and after its release and evolution stage in order to limit the cost …

Teaching Vocabulary Through Weekly Spelling Lessons: An Efficacy Study, Elizabeth Lindsey

Theses and Dissertations

In recent years, research has proved that vocabulary knowledge is highly correlated with reading comprehension and academic success. Despite the importance of vocabulary instruction, teachers are lacking a cohesive approach. Teachers are concerned about the quality and quantity of vocabulary instruction in the classroom. The purpose of this study was to determine if students in the Grand Forks Public Schools were learning their vocabulary words through indirect instruction using the Scott Foresman's Reading Street program. Twenty-seven fourth grade students were given clinical vocabulary assessments, as well as a researcher-designed assessment to determine percentage of vocabulary words known. Results indicated that …

Attention, Please, Abbey Marie Numedahl

Theses and Dissertations

A thesis of short fiction that examines the lives of contemporary American women through five short stories.

Analysis Of Multi-Platform Mobile Application Development, Courtney B. Thaden

Theses and Dissertations

The variety of mobile devices and their operating platforms has rapidly increased. With this increase come separate standards, programming languages, and distribution markets. Typically developers want to deliver their products to a variety of users encompassing various platforms; however choosing to develop using a native program for a platform can delay the development and release on another platform. Multi-platform development applications were created in order to deploy applications to various platforms in a more timely and cost efficient manner by using a single code base.

The purpose of this study was to investigate the multi-platform development applications MoSync, Appcelerator, and …

Restoration, Presence And Computer Use: How Computer Displays Incorporating Restorative Environments Effect Users' Sense Of Restoration And Presence, Jacob Bell

Theses and Dissertations

Recent technological advances provide opportunities for computer users to replace

desktop pictures with dynamic, audio-visual recordings. Such advances provide researchers with opportunities to better understand how specific video content may effect users' sense of restoration and presence. As described within Attention Restoration Theory, those perceiving restorative environments, which are found primarily within nature-based environments, experience a sense of restoration. Yet, prior research has largely focused on singular, and to an extent, non-interactive displays of restorative environments. The current research further investigated the restorative potential of environments having incorporated interactive, computer-based displays, with animated audio-visual environments. Participants were assigned to either …

Impacts Of Gas And Oil Development On Sharp-Tailed Grouse (Tympanuchus Phasianellus) Nest Success And Predator Dynamics In Western North Dakota, Paul Curtis Burr

Theses and Dissertations

Recent advancements in extraction technologies are resulting in rapid increases of gas and oil development in western North Dakota. This expansion of energy development may have unknown effects on local wildlife populations and the ecological interactions within and among species. Sharp-tailed grouse (Tympanuchus phasianellus) are a popular upland game bird species that rely on grassland habitat found throughout the state. Potential impacts of gas and oil development on the nest success of sharp-tailed grouse is an area of particular interest as it is an important factor in avian reproduction. Similarly, it is equally important to understand the impacts …

Attachment Sites Of Irreversible Cocaine Analogs On The Dopamine Transporter, Rejwi Acharya Dahal

Theses and Dissertations

The dopamine transporter (DAT) is an integral membrane protein that reuptakes dopamine (DA) from the extracellular space into the presynaptic neuron. DAT regulates dopaminergic neurotransmission as it maintains homeostatic synaptic DA levels in the brain. Psychostimulants such as cocaine disrupt DA homeostasis as it binds to DAT and prevents reuptake of DA. Excess DA in the synapse leads to prolonged dopaminergic neurotransmission, which is associated with cocaine related euphoria often leading to addiction.

The DAT consists of 12 transmembrane domains (TMs) with N- and C-termini facing the cytoplasm. TMs 1, 3, 6, and 8 make up the core of the …

Therapeutic Igy: Safe, Diverse, And Effective For Use Against Viral Targets, Nicole Noel Haese

Theses and Dissertations

Passive antibody treatments are used to target infectious disease, toxins, venoms, and cancer antigens. Recently, there has been an increased interest in the use of avian-derived antibody treatments such as IgY. IgY is the primary serum antibody isotype present in the avian system, and IgY treatments have already been demonstrated to be effective against a variety of bacterial and viral infectious agents. There are two forms of IgY expressed in anseriformes birds, a full length IgY that is functionally similar to mammalian IgG, and an alternatively spliced IgY, IgY(ÄFc), that is comparable to the mammalian F(ab')2 fragment. The difference in …

Part I: An Approach To The Synthesis Of Plakortethers A-E Part Ii: Rhodium-Catalyzed Intramolecular C-H Insertion On Diazosulfonates And Its Synthetic Applications, Duminda Shiromalee Liyanage

Theses and Dissertations

This research work consists of two independent studies. The first study is the development of a synthetic route to plakortethers A-E along with possible derivatives. The second study focuses on the synthetic applications of rhodium-catalyzed intramolecular C-H insertion on diazosulfonates.

Plakortethers (A-G) represent a set of marine natural products, which contain of a characteristic tetrasubstituted tetrahydrofuran fragment. This group of compounds was isolated from the Caribbean sponge Plakortis simplex. Their selective cytotoxic activity against the RAW 264-7 cell lines (murine macrophage) makes them promising candidates for biological studies and, along with their unusual structure, warrants the synthesis of these natural …

Effect Of A Nutrition Program On Eating Habits In Female Collegiate Athletes, Jorid Dagfinrud Oiestad

Theses and Dissertations

In the present study, an intervention took place using two female collegiate NCAA Division 1 (D1) teams. One team was randomized to be the experimental group, receiving the intervention of the 6-week nutrition education class Fueling for Performance (FFP). And the other team served as the control group, receiving no treatment. The purpose was to examine the effect of the FFP intervention on energy balance, body composition and self-efficacy compared to the control group, pre- and post- intervention.

The participants provided pre- and post intervention data through 3-day food records entered in MyPlate Super Tracker, wearing of a BodyMedia Senswear …

The Instruction Of Mindfulness: Developing Standards And Objectives For Mindfulness Training In Graduate Programs, Crystal Rofkahr

Theses and Dissertations

Mindfulness is an effective therapeutic tool for multiple disorders and

conditions. A set of standards, methods, assessments, and teacher characteristics had

not been formulated to effectively teach future mental health providers mindfulness.

This study utilized a Delphi Method to meet this need in the field. This methodology

was used to assemble a panel of experts to provide data on the best practices in teaching

mindfulness. The experts participated in three rounds of data collection. They provided

information pertaining to their ideal and real teaching standards, methods, and

assessments. They, then, narrowed down the concepts in each domain until consensus

was …