Digital Commons Network^™

Customized Feminine Hygiene Wash Containing Postbiotics From Lactobacillus Spp. To Treat Urinary Tract Infections (Uti), Veena G. Nair

Theses and Dissertations

Probiotics, which support host health by maintaining normal microbial flora, offer a promising approach for preventing recurrent infections. To evaluate the prophylactic potential of vaginal probiotics against urinary tract infections (UTIs), we conducted a study on 54 healthy South Indian women aged 18–40 who visited the Obstetrics and Gynaecology outpatient clinic at Trichy SRM Medical College and Research Centre between June and July 2022. Vaginal swabs were collected following ethical guidelines, and commensal microbiota were isolated for probiotic characterization, with the broader objective of developing a customized feminine hygiene wash enriched with vaginal postbiotics.

Lactobacilli cell-free supernatant (CFS) demonstrated potent …

Using Satellite Image Segmentation To Detect Trails, Jeremy Reynolds

Theses and Dissertations

This masters thesis proposes an innovative approach to satellite image segmentation by focusing on the detection and mapping of walking, hiking, and biking trails. The motivation behind this project comes from the underexplored area in segmentation techniques for trail identification and offers potential benefits for urban planning, environmental monitoring, and public health. The problem statement addresses the need for a model that can differentiate between various trail types and other natural or man-made elements. The project aims for efficiency and scalability in processing satellite imagery across different compute hardware. The work details several stages: researching existing segmentation techniques, specifically road …

Investigating The Thermodynamic Properties Of Fat10 And Fat10ylated Proteins, Aravind R

Theses and Dissertations

Degradation of proteins by the proteasome is crucial in regulating protein levels in the cell. Post-translational modifications, such as ubiquitylation and Fat10ylation, trigger proteasomal degradation of the substrate proteins. While ubiquitylation orchestrates multiple cellular processes, Fat10ylation is primarily involved in the inflammatory response. Unlike ubiquitin, recycled upon substrate degradation, Fat10 is degraded along with its substrate. Although the thermodynamic properties of the substrate are critical for effective proteasomal degradation, they remain poorly understood for the Fat10-proteasome pathway.

Here, we demonstrate that Fat10 exhibits markedly lower thermodynamic stability and faster unfolding kinetics compared to ubiquitin. This is due to the absence …

Rhythm Machine: Polyrhythmic Dimensions, James Elam

Theses and Dissertations

James Elam combines visual and aural mediums with technology to capture and manipulate sound. Here, Elam discusses how the repetitive elements in his work serve a practical purpose and add a conceptual and tactile layer to his sculptures and echo the hypnotic qualities in his DJ practice.

Ultraviolent, Jin Mateo Kim

Theses and Dissertations

How do you reconceive yourself in a society that has failed you? Jin Mateo Kim's works examine the reckoning of self-conception in postwar youth subculture of the 1960s.

To Swallow The Stars, Catie Dillon

Theses and Dissertations

Through abstract paintings of illuminated voids, Catie Dillon explores ideas of interconnectedness. In "To Swallow the Stars", she traces the layers of her process, examining the function of gesture, color, light, and space as a means to capture the ineffable.

You Are Not A Good Photographer, Byungsuk Yoon

Theses and Dissertations

This paper examines the medium of photography as a dynamic space for exploring the interplay between reality, memory, and imagination. It positions photography as an imperfect medium that operates on the boundary between predictability and uncertainty, embracing its inherent limitations as a source of creative potential. By addressing the tension between subjective experience and objective reality, this study redefines photography as a tool for continuous questioning and reinterpretation, highlighting its role in navigating the gaps between what is seen and what is imagined.

The Epiphany, Maja-Lisa Flodin-Ali

Theses and Dissertations

Maja-Lisa Flodin-Ali explores her interest in constructing spaces and occupying sets, while navigating the complexities of living with a mood disorder. She draws parallels between the multilayered nature of New York City and the layers of her own identity, retracing her personal history and examining its impact on her art practice. By engaging with classic narratives, such as Alice in Wonderland and The Wizard of Oz, Flodin-Ali reframes her journey and personal history, using these stories as a lens to explore healthier and more sustainable approaches to making.

Shapes That Hide Their Shadows, Jennifer Blaine

Theses and Dissertations

shapes that hide their shadows concerns itself with the mutability of memory. The complexities of girlhood to womanhood, and the way we are shaped by place and space, are explored through the artist recounting childhood memories connected to her grandparents' hometowns. Divided into three different sections, the artist discusses drawing as medium, creating a lexicon through using visual symbols, and the logistics of building your own archive.

The Farthest I Can Sense Time, Danielle Alhassid

Theses and Dissertations

This thesis examines the experiences of immigration, identity, and language through the lens of diasporic memory and intergenerational storytelling. At its core lies Communion of Empty Mouths (2024), a multi-channel video installation exploring the physical, communal, and ephemeral dimensions of language development and loss. The work juxtaposes live animation, tactile materials like ceramics, and experimental soundscapes to delve into the ancestral and embodied nature of linguistic expression.

Anchored in Yiddish poet Celia Dropkin’s text My Hands and inspired by familial narratives, the thesis critiques hierarchical and gendered dimensions of language, focusing on Yiddish as a diasporic medium of resistance and …

Xxx, Samuel Tucker Claxton

Theses and Dissertations

In XXX Tucker correlates the rise in online hookup apps and the fall of queer nightlife spaces to show how the internet has affected gay cruising spaces. They relate their installation-based work to the ideas of liminal spaces and Jean Baudrillard's

hyperreal. Further, they contextualize their practice within the scope of Robert Grober's work.

“Watch Me!” The Impact Of Training Experience On Dogs Social Referencing Human Emotional Cues, Madison Murray

Theses and Dissertations

Dogs utilized human facial expression and vocal tone to drive decision making during a novel object choice task, displaying a preference for negatively valenced objects. Training experience was not correlated to dog likelihood to social reference.

Resurrection In The Regensburg Pendant: Materials And Iconography, Devotional Object As Sacred Jewelry, Margarita Benacerraf

Theses and Dissertations

The Regensburg butterfly (1310-1320), an exquisitely crafted reliquary pendant, was found in the head of a fourteenth-century crucifix in 1991. The locket’s butterfly shape—and the ways in which the butterfly serves as a metaphor for Christ’s redemption—remains a fascinating window into late medieval Christianity and devotional practices in the medieval world.

Identifying Personality In Reptiles And Assessing Welfare Implications For Their Roles As Ambassador Animals In An Educational Setting, Valery Gonzalez

Theses and Dissertations

This study examined behavioral variability and personality in 13 reptiles used as ambassador animals at the American Museum of Natural History. Observations across seasons and novel object tests revealed individual differences, behavioral components, and correlations. Findings emphasize reptilian complexity, highlighting welfare implications while underscoring the need for further research.

Serious Music With Bea Witkin: An Upper West Side Audio Walk, Megan Hattie Stahl

Theses and Dissertations

Serious Music with Bea Witkin is a site-specific audio walk on New York City’s Upper West Side produced by Megan Hattie Stahl. This immersive, musical documentary explores and extends the life and work of composer Beatrice Witkin (1916-1990). Across four stationary chapters and three walking interludes, participants follow a one-mile route from Riverside Park to Straus Park by way of Witkin’s longtime residence on West End Avenue. Through guided narration, archival music, interviews and recordings of contemporary musicians sight-reading a 1985 string quartet piece by Witkin, Serious Music invites listeners to consider where music begins and ends.

Witkin, who graduated …

Activism Within The Music And Recorded Sound Archive, Julius Tanner

Theses and Dissertations

This thesis explores the integration of applied ethnomusicology within the recorded sound archive of the New York Public Library. The process of repatriating recorded sound through community engagement lead to the development and eventual reparative work of outdated subject headings and other descriptive language within the archive. This thesis also explores how cultural preservation of similar non-physical fields such as naming conventions within linguistics and the development of gastronationalism combats globalization and ultimately colonization.

Structures Of Feeling: Zoe Leonard And The Photographic Archive, Anika Zempleni

Theses and Dissertations

This thesis examines Zoe Leonard’s work with photographic archives. Focusing on three of Leonard’s archive-based projects—The Fae Richards Photo Archive (1993-96), You see I am here after all (2008), and In the Wake (2015-16)—this thesis argues that these works are connected through frameworks of feeling and subjectivity.

Aesthetics And Hidden Orientalism In Chicago's Nickerson Mansion, Julie Treumann

Theses and Dissertations

This thesis offers new research on the Sitting Room at the Nickerson Mansion, an 1883 Gilded Age-era house in Chicago, IL. As a rare extant example of neo-Islamic interior design, it provides a new lens on Orientalism in American domestic architecture and a new perspective on Mrs. Nickerson, a little-known female tastemaker of her time.

Equity's Garden, Nicole A. Barreras

Theses and Dissertations

Equity’s Garden is a narrative-driven video game that explores fairness and communication through the framework of a community garden. Players take on the role of the director of a garden's allocation committee, responsible for distributing planting spaces among neighborhood residents. Through branching storylines, players navigate the consequences of their decisions.

You Get That From Me, Robyn Duncan

Theses and Dissertations

You Get That From Me is a mixed-media, collage-based film that integrates personal portraits, allegorical maps, and digital collages with spoken narration to craft a stylistic memoir of a pivotal period in my life: the transition from childhood to motherhood.

Social Networks And Behavioral Adaptation Of Serrano Horses In A Rewilding Initiative In Spain, Ashley Bruno

Theses and Dissertations

Rewilding is a conservation measure that involves actively relocating species or restricting human land use to improve ecosystem sustainability. However, critics raise concerns that rewilding privileges ecosystem function over endangered species. Due to a lack of monitoring around species’ relocations, uncertainty lies in ecological outcomes and psychological, social, cultural impacts on affected animals. For this project, we collaborated with the non-profit Rewilding Europe that sought to conserve Serrano horses (Equus caballus), an ancient and under-studied breed of Spanish horse by relocating 11 individuals to a protected site in Guadalajara, Spain in June 2022. Our research aimed to address …

Testing Mediation Models Of Antisocial Behavior In The Context Of Parental Criminal Justice System Involvement, David Alfonso Tio

Theses and Dissertations

Parental criminal justice system involvement (CJSI) affects a significant portion of our children in a multitude of ways, including increasing the child’s risk for developing antisocial behaviors and, in doing so, perpetuating the intergenerational cycle of criminal offending that uniquely and unjustly afflicts marginalized communities of color and leaves behind what many have termed the ‘hidden victims’ of CJSI. This dissertation aimed to answer two research questions: 1. Does the division into two categories, the aggression, and rule breaking dimensions, provide a superior fitting model than the more commonly used unidimensional measure?; 2. Is it more accurate to model the …

Evolution Of Chitinases In Amphibians: A Multi-Faceted Group Of Enzymes With Dual Function In Digestion And At The Forefront Against Fungal Infections, Devashri Narayan

Theses and Dissertations

Chitinases are essential enzymes found in living organisms such as amphibians, and they ensure that amphibians survive in their varied ecosystems. They are crucial in the digestion and immunity of most organisms, including plants and animals. Chitinases’ diversity of functions is a testament to their evolutionary adaptability. The primary function of chitinases is the breakdown of chitin, a complex polymer of saccharides often found in the exoskeleton of insects and the walls of fungi. Amphibians that feed on insects make use of chitinases to hydrolyze chitin into simpler sugars that can be easily absorbed to extract the necessary nutrients from …

The Perceived Knowledge Of Effects Of Radiological Effects Amongst Radiologic Professionals, Kenneth Martinucci

Theses and Dissertations

X-ray, an accidental discovery in 1895, has been used to diagnose and treat various ailments. Despite the benefits of X-rays, it has been established that the radiation has the potential to cause harm to individuals and even death following its use. The harm associated with radiation has been evidenced in various historical tragedies globally, including the Chernobyl accidents, the Goiania accidents, and even the atomic bombings in Hiroshima and Nagasaki. These incidents highlight the potential hazards associated with radiation use. Individuals exposed to the radiation from the incidents had higher risks of cancer, neurological dysfunctions, congenital disabilities, predispositions to cardiovascular …

Mechanism Of Napthenic Acid Binding To Dissolved Organic Matter, Clarissa Jules

Theses and Dissertations

The oil sands in Alberta, Canada are being destroyed by oil extraction because remediation methods have proven largely ineffective. One toxic byproduct of oil extraction is a family of cyclical surfactant organic acids known as naphthenic acids (NAs). They are toxic to aquatic life, including fish, frogs, and aquatic birds. It is suspected that NAs bind to humic acid, a major organic component of soil, in dissolved organic matter in natural water, making them difficult to remove by conventional remediation methods. This problem prompts the following question: what is the binding mechanism between NAs and humic acid when dissolved in …

Improving The Safety Of N,N-Dimethylacetamide As A Potential Treatment For Preterm Birth Using A Vaginal Nanoformulation, Asad Mir

Theses and Dissertations

With no available treatment for preterm birth, the field of reproductive medicine has been repurposing small molecule candidates into vaginal nanoformulations as potential treatments for the condition. The commercial solvent N,N-Dimethylacetamide (DMA) has previously been shown to delay and prevent inflammation-induced preterm birth in a mouse model. A vaginal nanoformulation of DMA loaded into a self-nanoemulsifying drug delivery system (SNEEDS) was studied to see if it can also be efficacious. A side by-side histological comparison was done in the more pertinent tissues of the reproductive tract between the traditional formulation of DMA given intraperitoneally (IP) and the vaginal nanoformulation of …

Knocking Down Floral Symmetry Genes In Fedia Graciloflora (Caprifoliaceae), Jacob Vinson

Theses and Dissertations

Throughout angiosperm evolution, shifts between radial (actinomorphic) and bilateral (zygomorphic) symmetry have occurred repeatedly, often correlating with increased pollinator specialization and diversification. Evidence shows that the transcription factor CYCLOIDEA (CYC) plays a role in establishing the dorsoventral identity of a flower, leading to the formation of bilateral symmetry. Previous work in the lab used Virus-Induced Gene Silencing (VIGS) to transiently suppress the expression of four paralogous CYC genes: CYC2A, CYC2B, CYC3A, and CYC3B, in the non-model organism Fedia graciliflora (Caprifoliaceae), a species with strongly bilaterally symmetrical flowers nested within the more radially symmetric Valerianella. This study investigates the contributions of …

From Scars Into Stars: Transforming The Pain Of Trauma Into Purpose In Academic Writing, Joseph B. Weisler

Theses and Dissertations

This dissertation argues for the value of acknowledging students' emotions in the writing classroom, inspired by a pedagogy which has generated extensive controversy over the past 30 years. This project investigates how writing teachers might carefully allow students to harness their emotional reactions as they write. My project’s first chapter defends the value of victims' stories and the ''talking cure,'' following an explanation of how this psychological work would be introduced to a classroom setting, and with what tools, recognizing the potential disruptions that trauma may bring to a learning space. My second chapter turns to writing teachers who have …

Enhancing Emergency Response To The Active Shooter With Nims, Edwin A. Vazquez

Theses and Dissertations

The purpose of the following study is to identify components of the National Incident Management System (NIMS) that can be used to improve first responder deployment in critical incidents, such as in the occurrence of an Active Shooter (AS) and Active Deadly Threat (ADT). The Incident Command System (ICS), a component of NIMS, is the on-scene emergency management organization designed to aid in managing resources during planned and unplanned catastrophic events. An AS/ADT incident is typically planned by the perpetrator and unexpected to first responders, leaving them with limited time to respond to and neutralize this type of threat effectively. …

Aligning Exons, Introns, And Flanking Regions Of Cyc And Cuc Genes In Lonicera (Caprifoliaceae), Mark Mordukhay

Theses and Dissertations

The genus Lonicera (Caprifoliaceae) exhibits great diversity in floral symmetry, petal fusion, and organ arrangement, making it an ideal system for exploring the genetic basis of morphological evolution. We focus here on the roles of CYC and CUC gene families, (CYC2A, CYC2B, CYC3A, CYC3B, CUC2A, and CUC2B) and their potential contributions in shaping floral symmetry and organ fusion. The data set included nucleotide sequences from over 90 Lonicera species, extracted from samples collected from natural habitats or herbaria and then sequenced. A custom bioinformatics pipeline was developed in R using Bioconductor packages to automate BLAST searches, filter results, scan for …